CN1879791A - A nasal drop for treating rhinitis and method for preparing same - Google Patents

A nasal drop for treating rhinitis and method for preparing same Download PDF

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Publication number
CN1879791A
CN1879791A CNA2006100437803A CN200610043780A CN1879791A CN 1879791 A CN1879791 A CN 1879791A CN A2006100437803 A CNA2006100437803 A CN A2006100437803A CN 200610043780 A CN200610043780 A CN 200610043780A CN 1879791 A CN1879791 A CN 1879791A
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herba
fructus
rhinitis
flos
drop
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CNA2006100437803A
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CN100423752C (en
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白安福
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Shandong Bigao Pharmaceutical Co., Ltd.
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白安福
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Abstract

Disclosed is a drop agent for treating rhinitis and its preparing process, wherein the medicament comprises cocklebur fruit 18-30g, magnolia flower 9-15g, spearmint 9-15g, dahurian angelica root 9-15g, asarum herb 2-6g, gamene 12-20g, honeysuckle flower 12-20g, wild chrysanthemum flower 12-20g, licorice root 12-20g, herba schizonepetae 12-20g, Chinese ephedra 6-12g, yellow corktree bark 9-15g, anemarrhena rhizome 9-15g, schisandra fruit 12-20g, borneo camphor 8-12g, musk 0.4-0.8g and sesame oil 500g.

Description

A kind of phinamide for the treatment of rhinitis and preparation method thereof
Technical field
The present invention relates to a kind of medicament for the treatment of rhinitis, relate in particular to a kind of phinamide for the treatment of rhinitis and preparation method thereof.
Background technology
Rhinitis is meant that inflammation appears in nasal membrane, show as that nasal mucosa hyperemia, swelling, concha nasalis plumpness, air spots, nasal conchae hypertrophy or polypoid change, nasal cavity has purulent secretion, nasal obstruction, headache, malaise, limbs pain, watery nasal discharge, olfactory sensation and hypomnesis, closed rhinolalia etc. often appear in the patient.Can cause other complication as untimely correct treatment, as nasopharyngitis, sinusitis, catarrhal otitis media, suppurative otitis media, nasal deafness, the concurrent meningitis of frontal sinusitis even malignant change takes place for another example.At present, the medicine that is used for the treatment of rhinitis is a lot, and curative effect is different, and is all not ideal enough.The side effect that has curative effect big, that have is lower, the course of treatment long and easily recurrence.The purpose of this invention is to provide a kind of having no side effect, medicament of the treatment rhinitis of curative effect height, short treating period and difficult recurrence and preparation method thereof.
Summary of the invention
Phinamide of treatment rhinitis and preparation method thereof
The drop of treatment rhinitis is made up of following parts of medicines by weight:
Fructus Xanthii 18~30g Flos Magnoliae 9~15g Herba Menthae 9~15g
The Radix Angelicae Dahuricae 9~15g Herba Asari 2~6g Radix Rubiae 12~20g
Flos Lonicerae 12~20g Flos Chrysanthemi Indici 12~20g Radix Glycyrrhizae 12~20g
Herba Schizonepetae 12~20g Herba Ephedrae 6~12g Cortex Phellodendri 9~15g
The Rhizoma Anemarrhenae 9~15g Fructus Schisandrae Chinensis 12~20g Fructus Chebulae 12~20g
The fresh Oleum Sesami 500g of Borneolum Syntheticum 8~12g Moschus 0.4~0.8g
The preparation method of the drop of treatment rhinitis:
Earlier Fructus Xanthii in the prescription being put into stainless-steel pan fries little Jiao with slow fire and comes off to burr, remove burr impurity then, pulverize Fructus Xanthii, add Flos Magnoliae, Herba Menthae, the Radix Angelicae Dahuricae, Herba Asari, Radix Rubiae, Flos Lonicerae, Flos Chrysanthemi Indici, Radix Glycyrrhizae, Herba Schizonepetae, Herba Ephedrae, Cortex Phellodendri, the Rhizoma Anemarrhenae, Fructus Schisandrae Chinensis, Fructus Chebulae.More than 15 the flavor Chinese medicines add in the stainless-steel pan together, add fresh Oleum Sesami, add a cover and soaked 50~70 minutes, kept 12~15 minutes when being heated to boiling with slow fire, filtered while hot is separated medicine oil, medicinal residues, treat to add in the sterile sterile chamber rapidly when medicine oil is cooled to 65~75 ℃, add Borneolum Syntheticum, Moschus, seal, use the sterile chamber packing after cooling to room temperature, every bottled 15 milliliters, be the drop for the treatment of rhinitis.
The side separates:
Fructus Xanthii in the side, Herba Schizonepetae, Herba Ephedrae, Flos Magnoliae, the Radix Angelicae Dahuricae, all effects such as a surname's clearing the nasal passage, expelling pathogenic wind and eliminating dampness, diaphoresis, disinfection, detumescence, granulation promoting are arranged.
Radix Glycyrrhizae, Flos Lonicerae, Flos Chrysanthemi Indici have heat-clearing and toxic substances removing in the side, and relieving spasm to stop pain has specially good effect to sore swollen toxin.
Flos Magnoliae contains volatile oil in the side, and the effect of the nasal mucosa vessels of contraction is arranged, stuffy nose relieving sterilization, detumescence and apocenosis.
Rhizoma Anemarrhenae heat clearing away in the side, YIN nourishing, pathogenic fire reducing, antibiotic, antiinflammatory
Cortex Phellodendri heat-clearing and toxic substances removing in the side is treated skin ulcer
Radix Rubiae removing heat from blood, hemostasis, blood circulation promoting and blood stasis dispelling in the side
Borneolum Syntheticum, Moschus causing resuscitation with aromatic drugs, stuffy nose relieving, pain relieving, hemostasis and anti-inflammation in the side
Above medicine is got the medicinal liquid that makes with fresh Oleum sesami through heating to explode, and behind the collunarium nasal mucosa hematoma is had the oxidation Absorption, enhances metabolism and quickens to finish.This medicament heat-clearing and toxic substances removing, expelling wind and removing dampness, activating blood circulation to dissipate blood stasis, the evacuation of pus granulation promoting, a surname's clearing the nasal passage, pain relieving, hemostasis, antipruritic.To reach the purpose of treatment rhinitis, its unique significant curative effect is arranged with above-mentioned phinamide treatment chronic rhinitis, sinusitis.
Below by embodiment in detail, the present invention is described in detail.
Example:
Phinamide of treatment rhinitis and preparation method thereof
The drop of treatment rhinitis is made up of following parts of medicines by weight:
Fructus Xanthii 18~30g Flos Magnoliae 9~15g Herba Menthae 9~15g
The Radix Angelicae Dahuricae 9~15g Herba Asari 2~6g Radix Rubiae 12~20g
Flos Lonicerae 12~20g Flos Chrysanthemi Indici 12~20g Radix Glycyrrhizae 12~20g
Herba Schizonepetae 12~20g Herba Ephedrae 6~12g Cortex Phellodendri 9~15g
The Rhizoma Anemarrhenae 9~15g Fructus Schisandrae Chinensis 12~20g Fructus Chebulae 12~20g
The fresh Oleum Sesami 500g of Borneolum Syntheticum 8~12g Moschus 0.4~0.8g
The preparation method of the drop of treatment rhinitis
Earlier Fructus Xanthii in the prescription being put into stainless-steel pan fries little Jiao with slow fire and comes off to burr, remove burr impurity then, pulverize Fructus Xanthii, add Flos Magnoliae, Herba Menthae, the Radix Angelicae Dahuricae, Herba Asari, Radix Rubiae, Flos Lonicerae, Flos Chrysanthemi Indici, Radix Glycyrrhizae, Herba Schizonepetae, Herba Ephedrae, Cortex Phellodendri, the Rhizoma Anemarrhenae, Fructus Schisandrae Chinensis, Fructus Chebulae.Last 15 flavor Chinese medicines add in the stainless-steel pan together, add fresh Oleum Sesami, add a cover and soaked 50~70 minutes, kept 12~15 minutes when being heated to boiling with slow fire, filtered while hot is separated medicine oil, medicinal residues, treat to add in the sterile sterile chamber rapidly when medicine oil is cooled to 65~75 ℃, add Borneolum Syntheticum, Moschus, seal, use the sterile chamber packing after cooling to room temperature, every bottled 15 milliliters, be the drop for the treatment of rhinitis
Example two:
The drop of treatment rhinitis is made up of the medicine of following weight fraction:
Fructus Xanthii 18~22g Flos Magnoliae 10~13g Herba Menthae 11~13g
The Radix Angelicae Dahuricae 9~15g Herba Asari 3~5g Radix Rubiae 13~18g
Flos Lonicerae 13~18g Flos Chrysanthemi Indici 13~18g Radix Glycyrrhizae 13~18g
Herba Schizonepetae 13~18g Herba Ephedrae 8~10g Cortex Phellodendri 10~13g
The Rhizoma Anemarrhenae 10~13g Fructus Schisandrae Chinensis 13~17g Fructus Chebulae 12~17g
The fresh Oleum Sesami 500g of Borneolum Syntheticum 9~11g Moschus 0.4~0.8g
The medicaments preparation method of treatment rhinitis
Preparation method is with embodiment one.
Example three:
The drop of treatment rhinitis is made up of the medicine of following weight fraction:
Fructus Xanthii 20g Flos Magnoliae 12g Herba Menthae 12g Radix Angelicae Dahuricae 12g
Herba Asari 5g Radix Rubiae 15g Flos Lonicerae 15g Flos Chrysanthemi Indici 15g
Radix Glycyrrhizae 15g Herba Schizonepetae 15g Herba Ephedrae 9g Cortex Phellodendri 12g
The Rhizoma Anemarrhenae 12g 15g Fructus Chebulae 15g Borneolum Syntheticum 10g that distinguishes the flavor of
The fresh Oleum Sesami 500g of Moschus 0.6g
The preparation method of the drop of treatment rhinitis
Preparation method is with embodiment one.
Use the drop that the present invention treats rhinitis, accepted rhinitis patient 469 examples altogether for medical treatment from 2000 to 2005, male patient's 203 examples wherein, female patient 266 examples, 8 years old of age minimum, maximum 76 years old, and 469 routine patients are carried out follow-up investigation, clinical cure 382 examples, cure rate reaches 81.4%, effective 76 examples, invalid 11 examples, total effective rate 97.6%.The continuous drop 3-4 of patient with slight symptoms days take effect, and a week takes a turn for the better, recovery from illness in 15 days, the recovery from illness in 28 days of the continuous drop of patient with severe symptoms.Through 6-12 month tracing observation, phinamide did not have any untoward reaction, and non-stimulated symptom takes place, and proved that pure Chinese medicine phinamide treatment chronic rhinitis, allergic rhinitis, sinusitis are evident in efficacy, safe and reliable.
Model case:
Case one, Lee * *, woman 37 years old, year surplus in the of ill ten, the no olfactory sensation of having a headache, hypomnesis, suppurating property nasal mucus (wipe noses with 2~3 bag toilet papers every day) is not treated through hospital of a few family and is cured.Came here on January 20th, 2003, check and find the hyperemia of bilateral concha nasalis, enlargement has the purulence nasal mucus, and stench flavor is arranged.Get the phinamide drop, headache symptom complete obiteration in 3 days, nasal cavity is unobstructed, 15 days no purulence nasal mucus have olfactory sensation, after drop one all drug withdrawals again, do not have recurrence through visiting tour in 2 years, fully recover.
Case two: the king *, the man, 15 years old, 2000 was chronic rhinitis through local hospital diagnosis, and nasal obstruction, headache, dizziness are arranged, and suppurating property nasal mucus was taken out and to be groaned nose once in every 3-5 minute, and appearance is very painful, and the head of a family is invalid to seeking medical advice everywhere.On March 16th, 2003 is with phinamide drop 9 days, various transference cures, and recovery from illness is followed up a case by regular visits to and was not had recurrence in 2 years.
Case three: Lee *, woman 16 years old, middle school student suffered from rhinitis 3 years, and often tinnitus is accompanied in headache, and December in 2003 this patient's severe headache on the 16th can't be given a lesson, and asks for leave and is in.The head of a family is very worried, and evening on the 16th, the patient came here to remove the phinamide drop, and second day, the headache transference cure was returned to school on class, the back recovery from illness of two weeks.
Case four: Lee * *, man 31 years old suffered from allergic rhinitis 5 years, headache, and violent sneeze, nasal obstruction, flowing water sample tears, rhinocnesmus, tinnitus, hypomnesis drops tears.Fully recover with two week of the phinamide drop back that the present invention makes.
Case five: open * *, man 76 years old suffers from chronic rhinitis, and sinusitis 17 years was once done the puncture antral drainage, was shown effect severe headache, suppurating property nasal mucus, frowziness repeatedly again in nearly 2 years in 1991.Check to find the hyperemia of bilateral nasal mucosa, swelling, be nodositas, nasal cavity has purulent secretion, uses the phinamide drop on March 2nd, 2005, recovery from illness in 20 days there is not recurrence so far.

Claims (4)

1, a kind of drop for the treatment of rhinitis, it is characterized in that: it is made up of following parts of medicines by weight:
Fructus Xanthii 18~30g Flos Magnoliae 9~15g Herba Menthae 9~15g
The Radix Angelicae Dahuricae 9~15g Herba Asari 2~6g Radix Rubiae 12~20g
Flos Lonicerae 12~20g Flos Chrysanthemi Indici 12~20g Radix Glycyrrhizae 12~20g
Herba Schizonepetae 12~20g Herba Ephedrae 6~12g Cortex Phellodendri 9~15g
The Rhizoma Anemarrhenae 9~15g Fructus Schisandrae Chinensis 12~20g Fructus Chebulae 12~20g
The fresh Oleum Sesami 500g of Borneolum Syntheticum 8~12g Moschus 0.4~0.8g
2, a kind of drop for the treatment of rhinitis, it is characterized in that: it is made up of following parts of medicines by weight:
Fructus Xanthii 18~22g Flos Magnoliae 10~13g Herba Menthae 11~13g
The Radix Angelicae Dahuricae 9~15g Herba Asari 3~5g Radix Rubiae 13~18g
Flos Lonicerae 13~18g Flos Chrysanthemi Indici 13~18g Radix Glycyrrhizae 13~18g
Herba Schizonepetae 13~18g Herba Ephedrae 8~10g Cortex Phellodendri 10~13g
The Rhizoma Anemarrhenae 10~13g Fructus Schisandrae Chinensis 13~17g Fructus Chebulae 12~17g
The fresh Oleum Sesami 500g of Borneolum Syntheticum 9~11g Moschus 0.4~0.8g
3, a kind of drop for the treatment of rhinitis, it is characterized in that: it is made up of following parts of medicines by weight:
Fructus Xanthii 20g Flos Magnoliae 12g Herba Menthae 12g Radix Angelicae Dahuricae 12g
Herba Asari 5g Radix Rubiae 15g Flos Lonicerae 15g Flos Chrysanthemi Indici 15g
Radix Glycyrrhizae 15g Herba Schizonepetae 15g Herba Ephedrae 9g Cortex Phellodendri 12g
Rhizoma Anemarrhenae 12g Fructus Schisandrae Chinensis 15g Fructus Chebulae 15g Borneolum Syntheticum 10g
The fresh Oleum Sesami 500g of Moschus 0.6g
4, a kind of preparation method for the treatment of the drop of rhinitis: it is characterized in that: earlier Fructus Xanthii in the prescription is put into stainless-steel pan and fry little Jiao with slow fire and come off to burr, remove burr impurity then, pulverize Fructus Xanthii, add Flos Magnoliae, Herba Menthae, the Radix Angelicae Dahuricae, Herba Asari, Radix Rubiae, Flos Lonicerae, Flos Chrysanthemi Indici, Radix Glycyrrhizae, Herba Schizonepetae, Herba Ephedrae, Cortex Phellodendri, the Rhizoma Anemarrhenae, Fructus Schisandrae Chinensis, Fructus Chebulae.More than 15 the flavor Chinese medicines add in the stainless-steel pan together, add fresh Oleum Sesami, add a cover and soaked 50~70 minutes, kept 12~15 minutes when being heated to boiling with slow fire, filtered while hot is separated medicine oil, medicinal residues, treats to add in the sterile sterile chamber rapidly when medicine oil is cooled to 65~75 ℃, add Borneolum Syntheticum, Moschus, seal, use the sterile chamber packing after cooling to room temperature, be the drop finished product of treatment rhinitis.
CNB2006100437803A 2006-04-28 2006-04-28 A nasal drop for treating rhinitis and method for preparing same Expired - Fee Related CN100423752C (en)

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CN100423752C CN100423752C (en) 2008-10-08

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101288706B (en) * 2008-05-21 2011-07-20 迟静 Xanthium sibiricum honey compound soup for treating nasal sinusitis
CN101884727B (en) * 2009-05-12 2011-11-16 牛继明 Traditional Chinese medicine for treating rhinitis
CN102266393A (en) * 2011-08-03 2011-12-07 周永琴 External application medicament for treating allergic rhinitis and preparation method thereof
CN102988949A (en) * 2012-12-06 2013-03-27 刘春秀 Medicament for treating rhinitis
CN103830522A (en) * 2013-12-06 2014-06-04 济南新起点医药科技有限公司 Traditional Chinese medicine composition for treating rhinitis
CN103989788A (en) * 2014-05-29 2014-08-20 高广忠 Traditional Chinese medicine dropping liquid for treating rhinitis and preparation method thereof
CN104083498A (en) * 2014-06-30 2014-10-08 马文 Rhinitis ointment
CN105770232A (en) * 2016-05-23 2016-07-20 宋慧丽 Traditional Chinese medicine drops for treating rhinitis
CN107412456A (en) * 2017-05-05 2017-12-01 王效峰 Liquor-rhinitis, preparation method and applications
CN108992488A (en) * 2018-09-11 2018-12-14 张运鹏 A kind of Chinese medicine that treating rhinitis chronic and preparation method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1480189A (en) * 2003-07-10 2004-03-10 姜延德 Medication for treating rhinitis

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101288706B (en) * 2008-05-21 2011-07-20 迟静 Xanthium sibiricum honey compound soup for treating nasal sinusitis
CN101884727B (en) * 2009-05-12 2011-11-16 牛继明 Traditional Chinese medicine for treating rhinitis
CN102266393A (en) * 2011-08-03 2011-12-07 周永琴 External application medicament for treating allergic rhinitis and preparation method thereof
CN102266393B (en) * 2011-08-03 2013-04-03 周永琴 External application medicament for treating allergic rhinitis and preparation method thereof
CN102988949A (en) * 2012-12-06 2013-03-27 刘春秀 Medicament for treating rhinitis
CN102988949B (en) * 2012-12-06 2014-04-16 刘春秀 Medicament for treating rhinitis
CN103830522A (en) * 2013-12-06 2014-06-04 济南新起点医药科技有限公司 Traditional Chinese medicine composition for treating rhinitis
CN103989788A (en) * 2014-05-29 2014-08-20 高广忠 Traditional Chinese medicine dropping liquid for treating rhinitis and preparation method thereof
CN103989788B (en) * 2014-05-29 2016-04-27 高广忠 Chinese medicine dropping for the treatment of rhinitis and preparation method thereof
CN104083498A (en) * 2014-06-30 2014-10-08 马文 Rhinitis ointment
CN104083498B (en) * 2014-06-30 2016-08-24 马文 A kind of rhinitis ointment
CN105770232A (en) * 2016-05-23 2016-07-20 宋慧丽 Traditional Chinese medicine drops for treating rhinitis
CN107412456A (en) * 2017-05-05 2017-12-01 王效峰 Liquor-rhinitis, preparation method and applications
CN108992488A (en) * 2018-09-11 2018-12-14 张运鹏 A kind of Chinese medicine that treating rhinitis chronic and preparation method

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