CN104398699A - Traditional Chinese medicine composition for treating varicosity - Google Patents

Traditional Chinese medicine composition for treating varicosity Download PDF

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CN104398699A
CN104398699A CN201410653668.6A CN201410653668A CN104398699A CN 104398699 A CN104398699 A CN 104398699A CN 201410653668 A CN201410653668 A CN 201410653668A CN 104398699 A CN104398699 A CN 104398699A
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chinese medicine
medicine composition
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崔合芳
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Abstract

The invention discloses a traditional Chinese medicine composition for treating varicosity and belongs to the field of traditional Chinese medicines. The medicine comprises Chinese angelica, rhizoma corydalis, carthamus tinctorius, olibanum, panax notoginseng, leech, lumbricus, achyranthes bidentata, dandelion, a root of Chinese pulsatilla, morinda officinalis, homalomena occulta, honeysuckle, radix scrophulariae, radix paeoniae alba, a sophora flower, liquorice and the like. The medicine has significant effects of promoting blood circulation and easing a pain, significant, safe and reliable curative effects, and wide clinical application prospects.

Description

One treats cirsoid Chinese medicine composition
Technical field
The invention belongs to tcm field, particularly one treats cirsoid Chinese medicine composition.
Background technology
Varicosis is commonly called as, and " fried muscle lower limb " is the modal disease of Venous system, the main cause formed is because congenital vascular wall film is weaker or the identical posture of long-time maintenance seldom changes, blood accumulation lower limb, destroying vein valve when accumulating over a long period and to produce venous pressure too high, is the symptom of blood vessel enhancement skin surface.If treat not in time, can venous injury be caused, occur the symptom such as phlebothrombosis, edema, hemorrhage, ulcer, not only affect attractive in appearance, and have a strong impact on work and the life of patient.
Current treatment varicosis many employings operative therapy, namely makes veins of lower extremity endarterectomy.Modus operandi not only brings certain misery to patient, and costly, cure rate is low.Pharmacotherapy does not also have effect preferably medicine at present, for the traditional Chinese medical science, controls mainly with heat clearing and damp drying in the past, and the treatment of ignore removing heat from blood, invigorate blood circulation, detoxifying, therefore therapeutic effect is poor.
CN201410310453 discloses the Chinese medicine being used for the treatment of varicose veins of the lower extremity, and its formula is: Rhizoma Corydalis 9 ~ 13%, Herba Erodii 6 ~ 9%, Herba Artemisiae Anomalae 5 ~ 10%, Herba Schizonepetae 5 ~ 8%, Caulis Trachelospermi 4 ~ 8%, Radix Tripterygii Wilfordii 5 ~ 7%, Radix Ranunculi Ternati 4 ~ 7%, Radix Et Rhizoma Rhei 4 ~ 6%, Rhizoma Osmundae 4 ~ 7%, Radix Arnebiae (Radix Lithospermi) 2 ~ 5%, Radix et Rhizoma Thalictri 3 ~ 5%, thorn fossilia dentis mastodi 2 ~ 5%, Indigo Naturalis 2 ~ 5%, reed Ba Zi 3 ~ 5%, Cortex Pseudolaricis 3 ~ 5%, Cortex erythrinae 4 ~ 6%, Radix Et Rhizoma Nardostachyos 3 ~ 6%, Fructus Rubi 2 ~ 5%.
CN20041004360 discloses one and treats cirsoid Chinese medicine, is prepared from by Radix Angelicae Sinensis 15g, Radix Astragali 20g, pollen 10g, Radix Paeoniae Rubra 10g, Olibanum 10g, Myrrha 10g, Squama Manis 10g, Herba Schizonepetae 15g, Radix Saposhnikoviae 15g, Radix Aconiti 6g, Pericarpium Citri Reticulatae 10g, Fructus Chaenomelis 10g, Radix Stephaniae Tetrandrae 10g, Radix Glycyrrhizae 6g, Radix Cyathulae 10g.Cure mainly because of cold-damp invasion and attack, the varicose veins of the lower extremity stagnated caused by venation, and form congestion or lump, time serious, form the class diseases such as ulcer.
Summary of the invention
In order to make up the deficiencies in the prior art, the invention provides one and treat cirsoid Chinese medicine composition, it is evident in efficacy, safe and reliable, has wide potential applicability in clinical practice.
Technical scheme of the present invention is:
One treats cirsoid Chinese medicine composition, and this Chinese medicine composition is made up of the raw material of following weight portion: Radix Angelicae Sinensis 10-20 part, Rhizoma Corydalis 10-20 part, Flos Carthami 8-15 part, Olibanum 10-20 part, Radix Notoginseng 10-20 part, Hirudo 5-10 part, Pheretima 8-15 part, Radix Achyranthis Bidentatae 10-20 part, Herba Taraxaci 20-30 part, Radix Pulsatillae 10-20 part, Radix Morindae Officinalis 10-15 part, Rhizoma Homalomenae 10-15 part, Flos Lonicerae 20-30 part, Radix Scrophulariae 8-15 part, Radix Paeoniae Alba 10-20 part, Flos Sophorae 10-20 part, Radix Glycyrrhizae 10-20 part.
As the preferred embodiment of in above-mentioned Chinese medicine composition, this Chinese medicine composition, is made up of the raw material of following weight portion: Radix Angelicae Sinensis 15 parts, Rhizoma Corydalis 15 parts, 12 parts, Flos Carthami, Olibanum 15 parts, Radix Notoginseng 15 parts, Hirudo 8 parts, Pheretima 11 parts, Radix Achyranthis Bidentatae 15 parts, Herba Taraxaci 25 parts, the Radix Pulsatillae 15 parts, Radix Morindae Officinalis 12 parts, Rhizoma Homalomenae 12 parts, Flos Lonicerae 25 parts, Radix Scrophulariae 13 parts, the Radix Paeoniae Alba 15 parts, 15 parts, Flos Sophorae, 15 parts, Radix Glycyrrhizae.
Present invention also offers a kind of preparation method of above-mentioned Chinese medicine composition, it mainly comprises following step: get the above-mentioned traditional Chinese medicine powder of recipe quantity and be broken into powder, the alcoholic solution that volumetric concentration is 40% ~ 95% is added according to 4 ~ 10 times of powder gross weight, reflux, extract, three times, each return time is 2 ~ 5h, filters, filtrate recycling ethanol, cold filtration, washes with water, namely obtains Chinese medical concrete after drying; Those skilled in the art can technically prepare conventional Chinese medicine oral formulations clinically, as tablet, capsule etc. in this preparation method.
Source and the function of the present invention's Chinese crude drug used cure mainly:
Radix Angelicae Sinensis: hematonic; Enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation, cure mainly all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.Select the dry root of umbelliferae angelica.
Rhizoma Corydalis: invigorate blood circulation; Dissipating blood stasis; Regulate the flow of vital energy; Pain relieving.The all pains of main trusted subordinate's waist knee joint; Menoxenia; Lump in the abdomen; Metrorrhagia; Puerperal blood faints; Lochiorrhea; Traumatic injury.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.Select the dry tuber of papaveraceae plant corydalis.
Flos Carthami: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury, be suitable for various varicosis, peripheral neuritis, blood circulation is bad, lower limb numbness or the congestion such as livid purple.Select the dried floral of feverfew Flos Carthami.
Olibanum: regulating qi and activating blood, analgesic therapy, chases after poison, has strong bacteriostasis, and effectively can kill infusorian.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.Select the scented resin containing volatile oil of olive subject plant Olibanum wood output.
Radix Notoginseng: there is dissipating blood stasis hemostasis, effect of subduing swelling and relieving pain.Cure mainly spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, and breast ventral spine pain, tumbling down swells and ache.Select the dry root of Umbellales panax araliaceae plant.
Hirudo: containing hirudin, can delay and hinder blood coagulation, thus having blood coagulation resisting function.There is the effect such as treatment apoplexy, hypertension, the clear stasis of blood, amenorrhea, traumatic injury.At control cardiovascular and cerebrovascular disease and anticancer aspect, there is specially good effect.
Pheretima: i.e. Lumbricus, have heat clearing away, endogenous wind stopping, relieving asthma, dredging collateral, diuresis effect.Modern pharmacological research also proves, the multiple pharmacological effect such as Pheretima truly has antipyretic, calm, convulsion, relievings asthma, blood pressure lowering.Cure mainly high fanatical dry, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, hemiplegia etc.Select former medicine to wash dirt, pick up rapidly, dry.
Radix Achyranthis Bidentatae: invigorating the liver and kidney; Bone and muscle strengthening; Promoting blood circulation to restore menstrual flow; Ignite (blood) descending; Inducing diuresis for treating stranguria syndrome.Cure mainly soreness of waist and knee joint; Flaccidity and weakness of the lower limbs; Amenorrhea due to stagnation of blood; Dysmenorrhea; Puerperal abdominal pain due to blood stasis; Lump in the abdomen; Retention of placenta; Pyretic stranguria; Stranguria with blood; Traumatic injury; Carbuncle malignant boil; Laryngopharynx swelling and pain.Select the root of amaranthaceous plant Radix Achyranthis Bidentatae.
Herba Taraxaci: there is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, effect of inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.Be selected from the herb of dry Herba Taraxaci.
The Radix Pulsatillae: there is heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, effect of removing dampness and killing parasites.Note controls pyretic toxicity dysentery, epistaxis, internal hemorrhoid with bleeding, leukorrhagia, pudendal pruritus, carbuncle skin ulcer, scrofula.Select the dry root of the ranunculaceae plant Radix Pulsatillae.
Radix Morindae Officinalis: kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, cold womb is infertile, menoxenia, and few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity is soft.Select the dry root of Maguireothamnus speciosus Radix Morindae Officinalis.
Rhizoma Homalomenae: wind-damp dispelling, strengthening bone and muscle, pain relieving, detumescence.Dispelling the wind and dampness pathogens arthralgia pain, podomere is ached, and muscles and bones flaccidity is soft, stomachache, and carbuncle skin ulcer swells.For rheumatic arthralgia, chills and pain of the waist and kness, lower limb contracture numbness.Araeceae is selected to put down a dry rhizome for taro platymiscium Rhizoma Homalomenae.
Flos Lonicerae: heat-clearing and toxic substances removing, wind-heat dissipating, Flos Lonicerae can promote the release of adrenocortical hormone, has obvious inhibitory action to inflammation.For carbuncle furuncle, sore throat, erysipelas, warm blood fulminant dysentery, anemopyretic cold, epidemic febrile disease is generated heat.Select the flower that the dry flower of caprifoliaceae plant Radix Ophiopogonis or band are just opened.
Radix Scrophulariae: removing heat from blood YIN nourishing, eliminating fire and detoxication.Cure mainly: warm febrile disease and nutrient blood, fever of the body, excessive thirst, crimson tongue, send out speckle, hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency not awake, Tianjin hinder constipation, order puckery dim-sighted, throat larynx swells and ache, scrofula sucutaneous nodule, skin sore.Select the dry root of goatweed Radix Scrophulariae.
The Radix Paeoniae Alba: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.Select the dry root of ranunculaceae plant Radix Paeoniae.
Flos Sophorae: be Chinese medicine, the function of tool cooling blood for hemostasis, purging liver-fire.The property of Flos Sophorae bitter cold is comparatively strong, is longer than purging liver-fire, clearing away heat and cooling blood.Be used for bleeding due to blood-heat, liver-heat conjunctival congestion, have a headache dizzy, sore swells and ache
Radix Glycyrrhizae: raw with cooler, can eliminating fire and detoxication, relieving spasm to stop pain; Process with partially warm, can fall apart exterior cold, invigorating the spleen and replenishing QI.In addition, Radix Glycyrrhizae is also good at being in harmonious proportion the property of medicine, separates the poison of hundred medicines.Select the dry rhizome of glycyrrhizic legume.
Chinese medicine composition of the present invention, in treatment varicosis, compared with prior art has following advantage:
Medicine medicine source of the present invention is wide, is easy to get, cheap, and Chinese medicine composition effect of the present invention is comprehensive, and medication effect is better, has no side effect.
Detailed description of the invention
The present invention is further described below by way of specific embodiment:
(1) example of formulations part
embodiment 1 Chinese medicine composition of the present invention and preparation technology
The weight portion of Chinese medicinal components:: Radix Angelicae Sinensis 15 parts, Rhizoma Corydalis 15 parts, 12 parts, Flos Carthami, Olibanum 15 parts, Radix Notoginseng 15 parts, Hirudo 8 parts, Pheretima 11 parts, Radix Achyranthis Bidentatae 15 parts, Herba Taraxaci 25 parts, the Radix Pulsatillae 15 parts, Radix Morindae Officinalis 12 parts, Rhizoma Homalomenae 12 parts, Flos Lonicerae 25 parts, Radix Scrophulariae 13 parts, the Radix Paeoniae Alba 15 parts, 15 parts, Flos Sophorae, 15 parts, Radix Glycyrrhizae.
Get the above-mentioned Chinese crude drug of recipe quantity and be broken into coarse powder, add according to 6 times of coarse powder gross weight the alcoholic solution that volumetric concentration is 70%, reflux, extract, three times, each return time is 2.5h, and filter, filtrate recycling ethanol, namely obtains Chinese medical concrete after drying; Conventional Chinese medicine tablet is clinically prepared according to the preparation method of this area.Crude drug content is about 0.3g crude drug/grain.
embodiment 2 Chinese medicine composition of the present invention and preparation technology
The weight portion of Chinese medicinal components: Radix Angelicae Sinensis 10 parts, Rhizoma Corydalis 10 parts, 8 parts, Flos Carthami, Olibanum 10 parts, Radix Notoginseng 10 parts, Hirudo 5 parts, Pheretima 8 parts, Radix Achyranthis Bidentatae 10 parts, Herba Taraxaci 20 parts, the Radix Pulsatillae 10 parts, Radix Morindae Officinalis 10 parts, Rhizoma Homalomenae 10 parts, Flos Lonicerae 20 parts, Radix Scrophulariae 8 parts, the Radix Paeoniae Alba 10 parts, 10 parts, Flos Sophorae, 10 parts, Radix Glycyrrhizae.
Get the above-mentioned Chinese crude drug of recipe quantity and be broken into coarse powder, add according to 10 times of coarse powder gross weight the alcoholic solution that volumetric concentration is 90%, reflux, extract, three times, each return time is 2.5h, and filter, filtrate recycling ethanol, namely obtains Chinese medical concrete after drying; Conventional Chinese medicine tablet is clinically prepared according to the preparation method of this area.Crude drug content is about 0.3g crude drug/grain.
embodiment 3 Chinese medicine composition of the present invention and preparation technology
The weight portion of Chinese medicinal components: Radix Angelicae Sinensis 20 parts, Rhizoma Corydalis 20 parts, 15 parts, Flos Carthami, Olibanum 20 parts, Radix Notoginseng 20 parts, Hirudo 10 parts, Pheretima 15 parts, Radix Achyranthis Bidentatae 20 parts, Herba Taraxaci 30 parts, the Radix Pulsatillae 20 parts, Radix Morindae Officinalis 15 parts, Rhizoma Homalomenae 15 parts, Flos Lonicerae 30 parts, Radix Scrophulariae 15 parts, the Radix Paeoniae Alba 20 parts, 20 parts, Flos Sophorae, 20 parts, Radix Glycyrrhizae.
Preparation method is with embodiment 1.
(2) test examples part
Embodiment 4 Chinese medicine composition of the present invention is to the effectiveness study of varicose vein patients
1, experimenter's data
Experimenter is all from the varicose vein patients that certain the People's Hospital of city second accepted for medical treatment year February in February, 2011 to 2014.
Patients is:
1, superficial blood vessel varicose as Lumbricus, obviously protrudes skin, and varicose is bulk or nodositas;
2, leg has sour swollen sense, and evening is heavy, and morning is light, and skin has pigmentation, is a bit darkish in color, and skin has desquamation, pruritus, and ankle has edema;
3, have ascites, hepatosplenomegaly, hematemesis, melena, two lower limb extensive edema limb pain, aggravates during motion, pain time sometimes static, and night increases the weight of;
4, limbs have the sensation of difference, and limbs feel cold, limbs hectic fever, and suffering limb attenuates, and thicker skin has prickling sensation, titillation, feeling of numbness, burning sensation;
5, skin temperature raises, and has the sense of pain pain and tenderness;
6, toe (finger) first thickens, distortion, poor growth or stopping;
7, with gangrene and ulcer.
Therefrom filter out be applicable to doing clinical trial patient 120 example, wherein man 82 example, age 35-65 year, female 38 example, age 33-60 year.
2, medication is tested
Investigational agent: the tablet obtained by the embodiment of the present invention 1, specification: amount to crude drug amount and be about 0.3g crude drug/grain.
3, testing program
Tablet obtained by the oral embodiment of the present invention 1 of experimenter, each 2, every day 2 times.Within 4 weeks, be a course for the treatment of, treat 4 courses for the treatment of continuously.In medication process, the treatment such as itemized record adverse reactions of patients, physical recovery situation, medication impression situation.
4, evaluation criterion
(1) cure: varicosis symptom disappears completely, and make a definite diagnosis through doctor and return to one's perfect health.
(2) effective: varicosis symptom has improvement in various degree or alleviation.
(3) invalid: varicosis symptom is without any improvement, even more serious.
(4) untoward reaction: because of uncomfortable caused by drug administration or cause former disease other symptoms concurrent.
5, logging and analysis
Table 1 analysis of statistical results table
6, conclusion (of pressure testing)
As can be seen from statistical result, the tested patients taking Chinese medicine preparation of the present invention has no adverse reaction, cure rate 40%, total effective rate 92.5%.Visible, Chinese medicine composition of the present invention is used for the treatment of varicosis and has very significant curative effect, and technical advantage clearly.

Claims (5)

1. treat a cirsoid Chinese medicine composition, it is characterized in that being prepared from by the Chinese crude drug of following weight portion: Radix Angelicae Sinensis 10-20 part, Rhizoma Corydalis 10-20 part, Flos Carthami 8-15 part, Olibanum 10-20 part, Radix Notoginseng 10-20 part, Hirudo 5-10 part, Pheretima 8-15 part, Radix Achyranthis Bidentatae 10-20 part, Herba Taraxaci 20-30 part, Radix Pulsatillae 10-20 part, Radix Morindae Officinalis 10-15 part, Rhizoma Homalomenae 10-15 part, Flos Lonicerae 20-30 part, Radix Scrophulariae 8-15 part, Radix Paeoniae Alba 10-20 part, Flos Sophorae 10-20 part, Radix Glycyrrhizae 10-20 part.
2. the cirsoid Chinese medicine composition for the treatment of according to claim 1, is characterized in that being prepared from by the Chinese crude drug of following weight portion: Radix Angelicae Sinensis 15 parts, Rhizoma Corydalis 15 parts, 12 parts, Flos Carthami, Olibanum 15 parts, Radix Notoginseng 15 parts, Hirudo 8 parts, Pheretima 11 parts, Radix Achyranthis Bidentatae 15 parts, Herba Taraxaci 25 parts, the Radix Pulsatillae 15 parts, Radix Morindae Officinalis 12 parts, Rhizoma Homalomenae 12 parts, Flos Lonicerae 25 parts, Radix Scrophulariae 13 parts, the Radix Paeoniae Alba 15 parts, 15 parts, Flos Sophorae, 15 parts, Radix Glycyrrhizae.
3. the cirsoid Chinese medicine composition for the treatment of according to claim 1 and 2, is characterized in that: described Chinese medicine composition is oral formulations.
4. the cirsoid Chinese medicine composition for the treatment of according to claim 3, is characterized in that: described Chinese medicine composition is tablet or capsule.
5. the application of the cirsoid Chinese medicine composition of the treatment described in claim 1 or 2 in the cirsoid medicine of preparation treatment.
CN201410653668.6A 2014-11-18 2014-11-18 Traditional Chinese medicine composition for treating varicosity Withdrawn CN104398699A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177135A (en) * 2016-08-10 2016-12-07 徐柳 One is used for treating cirsoid medicine and preparation method thereof, application

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103860741A (en) * 2012-12-13 2014-06-18 青岛信立德中药技术研究开发有限公司 Lower limb varicose vein treatment traditional Chinese medicine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103860741A (en) * 2012-12-13 2014-06-18 青岛信立德中药技术研究开发有限公司 Lower limb varicose vein treatment traditional Chinese medicine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177135A (en) * 2016-08-10 2016-12-07 徐柳 One is used for treating cirsoid medicine and preparation method thereof, application
CN106177135B (en) * 2016-08-10 2020-04-17 徐柳 Medicine for treating varicosity and preparation method and application thereof

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Application publication date: 20150311