CN104398611A - Traditional Chinese medicinal preparation for treating solar dermatitis - Google Patents
Traditional Chinese medicinal preparation for treating solar dermatitis Download PDFInfo
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- CN104398611A CN104398611A CN201410745379.9A CN201410745379A CN104398611A CN 104398611 A CN104398611 A CN 104398611A CN 201410745379 A CN201410745379 A CN 201410745379A CN 104398611 A CN104398611 A CN 104398611A
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- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/232—Angelica
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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Abstract
The invention provides a traditional Chinese medicinal preparation for treating solar dermatitis. The traditional Chinese medicinal preparation is prepared from zaocys dhumnades, angelica dahurica, peach seeds, portulaca oleracea, dark plum fruits, mint, platycodon grandiflorus, mulberry leaves, scorched hawthorn fruits, raw licorice and chrysanthemum, and each medicament synergistically acts to achieve the effects of expelling wind, calming endogenous wind, dispersing blood stasis, dredging collaterals, clearing heat, treating poison, caring skin and resisting allergy, so that the aim of conditioning and treating solar dermatitis is fulfilled. Clinical observation results show that the traditional Chinese medicinal preparation has clear conditioning and treatment effects on solar dermatitis, and also has good treatment effects on chronic dermatitis caused by various factors.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation being used for the treatment of dermatitis, particularly relate to a kind of Chinese medicine preparation for the treatment of solar dermatitis, belong to the field of Chinese medicines.
Background technology
Solarized dermatitis and solar dermatitis, also known as sunburn or sunburn, be a kind of acute inflammatory reaction that normal skin produces after being exposed to the sun, show as erythema, edema, vesicle and pigmentation, desquamation.Primary disease the end of spring and the beginning of summer is common, is apt to occur in child, women, slider and water surface worker, and the intensity of its reaction is relevant with light intensity, irradiation time, the individual colour of skin, body constitution, race etc.The action spectrum mainly UVB of solarized dermatitis, normal skin makes intradermal various kinds of cell discharge the inflammatory mediators such as histamine, 5-hydroxy tryptamine, kassinin kinin through ultraviolet radiation, makes intradermal vasodilation, permeability increase.
The clinical manifestation of solarized dermatitis: after shining red-letter day spring and summer more than a few hours to ten hour, occur boundary clearly erythema, cerise at exposure position, vesicle, erosion can appear in severe patient; Erythema color is shown in dimmed, desquamation subsequently, leaves pigmentation or goes down.Conscious burn feeling or sensation of pricking, often affect sleep.The lighter fully recovered in 2 ~ 3 days, and severe patient could recover for about one week.Few patients can be occurred together conjunctival congestion, blepharoedema.The wide person of Exposure to Sunlight area, can cause General Symptoms, as heating, fear of cold, headache, weak, nauseating and general malaise etc.
At present, the medicine of solarized dermatitis is treated: the lighter's antihistaminic, severe one or curative effect not good enough person's low-dose Oral glucocorticoid, aspirin or indomethacin.These medicines are mostly hormone medicine, life-time service, not only cause certain damage to skin, other organ, and can not from the skin quality of radical change to sun sensitivity.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation being used for the treatment of chronic dermatitis.
Chinese medicine preparation of the present invention, carry out compatibility with Zaocys, the Radix Angelicae Dahuricae, Semen Persicae, Herba Portulacae, Fructus Mume, Herba Menthae, Radix Platycodonis, Folium Mori, Fructus Crataegi (parched to brown), Radix Glycyrrhizae, Flos Chrysanthemi for raw material, effect of each medicine is produced collaborative, play altogether and search that wind relieves dizziness, high fever, infantile convulsions, epilepsy, etc., disperse blood stasis and dredge collateral, heat clearing away treat poison, treat the function of skin antiallergic, thus the conditioning realized chronic dermatitis and therapeutic purposes.
The present invention, according to the pathological characters of the many stasis of bloods of chronic dermatitis prolonged illness, pathogen usually intruding into collateral in protracted disease, adds that the morbidity nothing that allergy has " wind " locates feature surely, is monarch drug, searches wind, dredging collateral, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. with Zaocys.With the Radix Angelicae Dahuricae, Semen Persicae for ministerial drug, blood circulation promoting and blood stasis dispelling, loose wind are sensible, and strengthening monarch drug is by dispeling the wind with antianaphylactic effect.With the Radix Angelicae Dahuricae, Semen Persicae for ministerial drug, blood circulation promoting and blood stasis dispelling, loose wind are sensible, and strengthening monarch drug is by dispeling the wind with antianaphylactic effect.With Herba Portulacae, Fructus Mume, Herba Menthae, Radix Platycodonis, Folium Mori for adjuvant drug, heat-clearing and toxic substances removing, the treatment poison that dispels the wind, convergence skin protection, foster skin treat skin, directly act on chronic dermatitis, object of going directly.With Fructus Crataegi (parched to brown), Radix Glycyrrhizae, Flos Chrysanthemi for making medicine, from interior solution its poison, change its stasis of blood, clearly its heat, lose its poison.Full side gathers altogether and searches that wind relieves dizziness, high fever, infantile convulsions, epilepsy, etc., disperse blood stasis and dredge collateral, heat clearing away are treated poison, treated the function of skin antiallergic.
Chinese medicine preparation of the present invention carries out proportioning by following weight portion: Zaocys 20-30 part, Radix Angelicae Dahuricae 25-35 part, Semen Persicae 15-25 part, Herba Portulacae 15-25 part, Fructus Mume 5-15 part, Herba Menthae 5-15 part, Radix Platycodonis 5-15 part, Folium Mori 5-15 part, Fructus Crataegi (parched to brown) 5-15 part, Radix Glycyrrhizae 5-15 part, Flos Chrysanthemi 5-15 part.
Optimum ratio: Zaocys 20-26 part, Radix Angelicae Dahuricae 28-32 part, Semen Persicae 17-23 part, Herba Portulacae 18-22 part, Fructus Mume 7-12 part, Herba Menthae 7-12 part, Radix Platycodonis 7-12 part, Folium Mori 7-12 part, Fructus Crataegi (parched to brown) 7-12 part, Radix Glycyrrhizae 7-12 part, Flos Chrysanthemi 7-12 part.
Optimum proportioning: Zaocys 24 parts, the Radix Angelicae Dahuricae 30 parts, 20 parts, Semen Persicae, Herba Portulacae 20 parts, Fructus Mume 10 parts, Herba Menthae 10 parts, Radix Platycodonis 10 parts, 10 parts, Folium Mori, Fructus Crataegi (parched to brown) 10 parts, Radix Glycyrrhizae 10 parts, Flos Chrysanthemi 10 parts.
The oral preparations that Health-protection traditional Chinese medicinal preparation of the present invention can be prepared into by the common process of pharmaceutics and adjuvant, as capsule, granule, tablet or oral liquid etc.
Below for solar dermatitis, by clinical observation and statistics, the effect to Health-protection traditional Chinese medicinal preparation treatment chronic dermatitis of the present invention is described.
1, clinical observation object: typical daylight dermatitis patients 50 example selecting clinical diagnosis, man, female has, the age 20-60 year.
2, clinical symptoms: after Exposure to Sunlight, erythema, edema or vesicle appear in local skin.
3, Therapeutic Method: take granules medicine of the present invention.Specification: 6g/ bag, 30 bags/box.Usage: each one bag sooner or later, warm water is directly taken after mixing it with water, or melts oral.The course for the treatment of: 15 days 1 cycles, overview 1-2 cycle.
4, criterion is treated: cure: erythema, edema or vesicle disappear completely; Nothing is burnt, pain; Pigmentation spots is dimmed gradually.Effective: erythema, edema or vesicle obviously disappear substantially; Substantially without burning, pain.Invalid: erythema, edema or vesicle do not disappear; Burn, pain is obvious.
5, measurement result: cure: 42 examples, account for 84%, effectively: 8 examples, account for 16%, invalid 0 example.Total effective rate 100%.
Above-mentioned clinical observation result shows, Chinese medicine preparation of the present invention has good therapeutical effect for solar dermatitis, and the chronic dermatitis simultaneously caused for a variety of causes also has good therapeutic effect.
Detailed description of the invention
Below by specific embodiment, the proportioning raw materials of pharmaceutical preparation of the present invention, preparation and usage and dosage are described further.
The preparation of embodiment 1, granules medicine
Composition of raw materials: Zaocys 24 parts, the Radix Angelicae Dahuricae 30 parts, 20 parts, Semen Persicae, Herba Portulacae 20 parts, Fructus Mume 10 parts, Herba Menthae 10 parts, Radix Platycodonis 10 parts, 10 parts, Folium Mori, Fructus Crataegi (parched to brown) 10 parts, Radix Glycyrrhizae 10 parts, Flos Chrysanthemi 10 parts;
Preparation technology: prepare the common process of granule by pharmaceutics and adjuvant is prepared from;
Specification: 6g/ bag;
Usage and dosage: each 1 time sooner or later, each serving 6g; 15 days 1 cycles, the overview 1-2 cycle.
The preparation of embodiment 2, capsule medicine
Composition of raw materials: Zaocys 26 parts, the Radix Angelicae Dahuricae 32 parts, 23 parts, Semen Persicae, Herba Portulacae 22 parts, Fructus Mume 12 parts, Herba Menthae 12 parts, Radix Platycodonis 12 parts, 12 parts, Folium Mori, Fructus Crataegi (parched to brown) 12 parts, Radix Glycyrrhizae 12 parts, Flos Chrysanthemi 12 parts;
Preparation technology: prepare the common process of capsule by pharmaceutics and adjuvant is prepared from;
Specification: every 0.3g;
Usage and dosage: each 1 time sooner or later, each serving 1.5g; 15 days 1 cycles, the overview 1-2 cycle.
The preparation of embodiment 3, tablet medicine
Composition of raw materials: Zaocys 20 parts, the Radix Angelicae Dahuricae 28 parts, 17 parts, Semen Persicae, Herba Portulacae 18 parts, Fructus Mume 7 parts, Herba Menthae 7 parts, Radix Platycodonis 7 parts, 7 parts, Folium Mori, Fructus Crataegi (parched to brown) 7 parts, Radix Glycyrrhizae 7 parts, Flos Chrysanthemi 7 parts;
Preparation technology: prepare the common process of tablet by pharmaceutics and adjuvant is prepared from;
Specification: every sheet 1.0g;
Usage and dosage: each 1 time sooner or later, each serving 5.0g; 15 days 1 cycles, the overview 1-2 cycle.
The preparation of embodiment 4, pill medicine
Composition of raw materials: Zaocys 30 parts, the Radix Angelicae Dahuricae 35 parts, 25 parts, Semen Persicae, Herba Portulacae 25 parts, Fructus Mume 15 parts, Herba Menthae 15 parts, Radix Platycodonis 15 parts, 15 parts, Folium Mori, Fructus Crataegi (parched to brown) 15 parts, Radix Glycyrrhizae 15 parts, Flos Chrysanthemi 15 parts;
Preparation technology: prepare the common process of pill by pharmaceutics and adjuvant is prepared from;
Specification: every 0.05g;
Usage and dosage: each 1 time sooner or later, each serving 3.0g; 15 days 1 cycles, the overview 1-2 cycle.
The preparation of embodiment 5, oral liquid
Composition of raw materials: Zaocys 20 parts, the Radix Angelicae Dahuricae 25 parts, 15 parts, Semen Persicae, Herba Portulacae 15 parts, Fructus Mume 5 parts, Herba Menthae 5 parts, Radix Platycodonis 5 parts, 5 parts, Folium Mori, Fructus Crataegi (parched to brown) 5 parts, Radix Glycyrrhizae 5 parts, Flos Chrysanthemi 5 parts;
Preparation technology: prepare the common process of oral liquid by pharmaceutics and adjuvant is prepared from;
Specification: every bottle of 10ml;
Usage and dosage: each 1 time sooner or later, each serving 20ml.15 days 1 cycles, the overview 1-2 cycle.
In the various embodiments described above, each proportioning raw materials is all with parts by weight.
Claims (5)
1. one kind is used for the treatment of the Chinese medicine preparation of solar dermatitis, with Zaocys, the Radix Angelicae Dahuricae, Semen Persicae, Herba Portulacae, Fructus Mume, Herba Menthae, Radix Platycodonis, Folium Mori, Fructus Crataegi (parched to brown), Radix Glycyrrhizae, Flos Chrysanthemi for raw material, the oral preparations be prepared into by common process and the adjuvant of pharmaceutics.
2. be used for the treatment of the Chinese medicine preparation of solar dermatitis as claimed in claim 1, it is characterized in that: each raw material carries out proportioning by following weight portion: Zaocys 20-30 part, Radix Angelicae Dahuricae 25-35 part, Semen Persicae 15-25 part, Herba Portulacae 15-25 part, Fructus Mume 5-15 part, Herba Menthae 5-15 part, Radix Platycodonis 5-15 part, Folium Mori 5-15 part, Fructus Crataegi (parched to brown) 5-15 part, Radix Glycyrrhizae 5-15 part, Flos Chrysanthemi 5-15 part.
3. be used for the treatment of the Chinese medicine preparation of solar dermatitis as claimed in claim 1, it is characterized in that: each raw material carries out proportioning by following weight portion: Zaocys 20-26 part, Radix Angelicae Dahuricae 28-32 part, Semen Persicae 17-23 part, Herba Portulacae 18-22 part, Fructus Mume 7-12 part, Herba Menthae 7-12 part, Radix Platycodonis 7-12 part, Folium Mori 7-12 part, Fructus Crataegi (parched to brown) 7-12 part, Radix Glycyrrhizae 7-12 part, Flos Chrysanthemi 7-12 part.
4. be used for the treatment of the Chinese medicine preparation of solar dermatitis as claimed in claim 1, it is characterized in that: each raw material carries out proportioning by following weight portion: Zaocys 24 parts, the Radix Angelicae Dahuricae 30 parts, 20 parts, Semen Persicae, Herba Portulacae 20 parts, Fructus Mume 10 parts, Herba Menthae 10 parts, Radix Platycodonis 10 parts, 10 parts, Folium Mori, Fructus Crataegi (parched to brown) 10 parts, Radix Glycyrrhizae 10 parts, Flos Chrysanthemi 10 parts.
5. be used for the treatment of the Chinese medicine preparation of solar dermatitis as claimed in claim 1, it is characterized in that: described oral preparations is capsule, granule, pill, tablet or oral liquid.
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| CN201410745379.9A CN104398611A (en) | 2014-12-09 | 2014-12-09 | Traditional Chinese medicinal preparation for treating solar dermatitis |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410745379.9A CN104398611A (en) | 2014-12-09 | 2014-12-09 | Traditional Chinese medicinal preparation for treating solar dermatitis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108465061A (en) * | 2018-06-01 | 2018-08-31 | 四川省中医药科学院 | It is a kind of to be used to treat pharmaceutical composition of Facial Recurrent Dermatitis and its preparation method and application |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102988564A (en) * | 2012-11-22 | 2013-03-27 | 王雪娟 | Traditional Chinese medicine composition for treating solar dermatitis |
| CN103263623A (en) * | 2013-04-22 | 2013-08-28 | 缪友道 | Traditional Chinese medicine for treating solar dermatitis |
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- 2014-12-09 CN CN201410745379.9A patent/CN104398611A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102988564A (en) * | 2012-11-22 | 2013-03-27 | 王雪娟 | Traditional Chinese medicine composition for treating solar dermatitis |
| CN103263623A (en) * | 2013-04-22 | 2013-08-28 | 缪友道 | Traditional Chinese medicine for treating solar dermatitis |
Non-Patent Citations (3)
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| 匡德芳、谷朝霞: "清热除湿汤治疗日光性皮炎15例疗效观察", 《牡丹江医学院学报》 * |
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| 詹文涛、孟如主编: "《难治病中医证治精华》", 28 February 2001, 云南科技出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108465061A (en) * | 2018-06-01 | 2018-08-31 | 四川省中医药科学院 | It is a kind of to be used to treat pharmaceutical composition of Facial Recurrent Dermatitis and its preparation method and application |
| CN108465061B (en) * | 2018-06-01 | 2021-03-30 | 四川省中医药科学院 | Pharmaceutical composition for treating recurrent facial dermatitis and preparation method and application thereof |
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Application publication date: 20150311 |