CN103041171B - Medicine for treatment of menopause vertigo - Google Patents

Medicine for treatment of menopause vertigo Download PDF

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CN103041171B
CN103041171B CN201210583644.9A CN201210583644A CN103041171B CN 103041171 B CN103041171 B CN 103041171B CN 201210583644 A CN201210583644 A CN 201210583644A CN 103041171 B CN103041171 B CN 103041171B
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parts
medicine
treatment
climacteric
vertigo
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CN103041171A (en
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张引民
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Abstract

The invention discloses medicine for treatment of menopause vertigo, which aims to solve the problem of treatment of menopause vertigo, and is characterized by being prepared by processing various Chinese medicines. The material formula comprises the following raw materials in proportion by weight: 10-20 parts of loofah sponge, 8-15 parts of edible tulip, 8-15 parts of glabrous sarcandra herb, 6-10 parts of windpipe trachea, 6-10 parts of pawpaw, 8-15 parts of inula helenium, 6-10 parts of herb of rose glorybind, 3-6 parts of cassia twig and 3-6 parts of chalcanthite. The clinical experiment proves that the medicine has the characteristics of good curative effect and higher safety for treatment of menopause vertigo, and is worthy of clinical application and popularization.

Description

A kind of dizzy medicine of climacteric for the treatment of
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of dizzy medicine of climacteric for the treatment of.
Background technology
Vertigo is orientation or the para equilibrium of human body to spatial relationship, is in fact also non-existent self or outdoor scene illusion of movement of one.Cause that dizzy disease is a lot, except OtorhinolaryngologicDiseases Diseases, also relate to the disease of internal medicine, Neurology Department and orthopaedics.Must, dizzy two classes that are divided into: 1. also around i.e. property, vestibule peripheral vertigo of true vertigo, be paroxysmal foreign object or the rotation of itself, topple over sense, degenerate and feel, severe symptoms, how with significantly feeling sick, the vegetative nerve symptom such as vomiting, persistent period is short, and to a few hours, seldom exceed a couple of days or several weeks person tens of seconds; 2. nonsystemic vertigo is also central, nonsystemic vertigo, be foreign object or the sense that shambles of self, or rock left and right or front and back, while watching mobiles attentively, or increase the weight of under noisy environment, symptom is lighter, the vegetative nerve symptom that occurs together is not obvious, persistent period is longer, can reach the several months long, is more common in the illness such as brain and eye.
Climacteric is dizzy belongs to a kind of more special dizzy.So-called climacteric, is that women progresses into senile transition stage (between about 45~55 years old) from period of sexual maturity (period of duration), is an important and especially significantly stage of physiological change in human senility process.The a series of changes that bring to body because of hypo-ovaria, wherein a kind of symptom is dizzy, this kind dizzy shows as dizzy, the outdoor scene rotation of breaking out, dare not open eyes, generally with feeling sick, be in a cold sweat, the symptom such as pale complexion, after outbreak, recover normal, audition and vestibular function examination are all normal, and this kind of dizzy outbreak repeatedly, are difficult to automatic control.The very complexity of pathogenesis that climacteric is dizzy, relevant with the vascular dysfunctions of cerebral circulation, there is autonomic nervous dysfunction's situation in some cases.
The dizzy treatment of current clinical climacteric is main mainly with treatment climacteric syndrome, still lacks dizzy medicine of simple treatment climacteric, or it is dizzy to select the medicine of the common vertigo for the treatment of to treat climacteric.Chinese medicine adopts the medicine of suppressing the hyperactive liver and subsiding YANG or kidney tonifying, essence replenishing more, there is following defect but above therapeutic scheme treatment climacteric is dizzy: 1. dizzy with dizzy pathogenesis is not identical climacteric, climacteric is dizzy relevant with the vascular dysfunctions of cerebral circulation, time or vasospasm, cerebral tissue ischemia and sending out, time or excessive with vasodilation, brain perfusion increases suddenly relevant; 2. suppressing the hyperactive liver and subsiding YANG medicine, as Cornu Saigae Tataricae, Carapax Eretmochelydis, Ramulus Uncariae Cum Uncis, Concha Haliotidis, and relieving spasm by subduing liver-wind class medicine, as Rhizoma Gastrodiae, Bombyx Batryticatus, Scorpio, for climacteric dizzy card easily cause and exceed the proper limits in righting a wrong, cause brain hemoperfusion obstacle; 3. automatic regulation function dizzy and cerebral circulation is not normal relevant climacteric, and this point is not all paid close attention in Western medicine and Chinese medicine treatment.
Summary of the invention
Technical assignment of the present invention is for above the deficiencies in the prior art, provides a kind of curative effect sure dizzy medicine for the treatment of climacteric.
The technical scheme that the present invention solves its technical problem is: a kind of dizzy medicine of climacteric for the treatment of, it is characterized in that being processed by plurality of Chinese, its composition of raw materials and weight proportion are: 10 ~ 20 parts of Retinervus Luffae Fructuss, 8 ~ 15 parts of Pseudobulbus Cremastrae Seu Pleioness, 8 ~ 15 parts of Herba Sarcandraes, 6 ~ 10 parts of Rhizoma Paridis, 6 ~ 10 parts of Fructus Chaenomeliss, 8 ~ 15 parts of Radix Inulaes, 6 ~ 10 parts of Herba Calystegiae Japonicae, 3 ~ 6 parts of Ramulus Cinnamomi, 3 ~ 6 parts, stone gallbladder.
Its optimum weight proportioning is: 15 parts of Retinervus Luffae Fructuss, 10 parts of Pseudobulbus Cremastrae Seu Pleioness, 10 parts of Herba Sarcandraes, 8 parts of Rhizoma Paridis, 8 parts of Fructus Chaenomeliss, 10 parts of Radix Inulaes, 8 parts of Herba Calystegiae Japonicae, 5 parts of Ramulus Cinnamomi, 5 parts, stone gallbladder.
Wherein said: Retinervus Luffae Fructus is the vascular bundle of the dry mature fruit of cucurbitaceous plant Fructus Luffae Luffa cylindrica (L.) Roem..Sweet, flat.Return lung, stomach, Liver Channel.Merit can dredging collateral, invigorates blood circulation, and dispels the wind.
Pseudobulbus Cremastrae Seu Pleiones is orchid Cremastra appendiculata Cremastra appendiculata (D.Don) Makino, pleione bulbocodioides Pleione bulbocodioides(Franch.) the dry pseudobulb of Rolfe or Pleione yunnanensis Pleione yunnanensis Rolfe.Nature and flavor are sweet, micro-pungent, cold.Enter liver, stomach warp.Merit can heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.
Herba Sarcandrae is the dry Herb of Chloranthaceae plant plait Corallium Japonicum Kishinouye Sarcandra glabra (Thunb.) Nakai.Bitter, pungent, flat.GUIXIN, Liver Channel.Merit can clearing away heat and cooling blood, the speckle removing of invigorating blood circulation, dispelling wind and removing obstruction in the collateral.
Rhizoma Paridis is the rhizome of liliaceous plant Rhizoma Paridis Paris polyphylla Sm..Hardship, is slightly cold.Slightly poisonous.Enter Liver Channel.Merit can heat-clearing and toxic substances removing, detumescence, spasmolytic.
Fructus Chaenomelis is the dry almost ripe fruit of rosaceous plant chaenomeles lagenaria Chaenomeles speciosa.Nature and flavor acid, temperature.Return liver, spleen channel.Merit can suppressing the hyperactive liver relaxing muscles and tendons, stomach function regulating removing dampness.
Radix Inulae is the dry root of feverfew Radix Inulae or Radix Inulae.Pungent, bitter, temperature.Return liver, spleen channel.Merit can invigorating the spleen and regulating the stomach, promoting the flow of QI for relieving the stagnancy, and pain relieving is antiabortive.
Herba Calystegiae Japonicae is root and the herb of convolvulaceous plant Japan day sword Calystegia dahurica (Herb.) Choisy.Sweet, cold.Merit can heat clearing away, YIN nourishing, blood pressure lowering, diuresis.
Ramulus Cinnamomi is the withe of canella Cortex Cinnamomi Cinnamomum cassia Presl.Nature and flavor acrid, sweet, warm.Enter the heart, lung, urinary bladder channel.Merit can relieving the exterior syndrome by diaphoresis, promoting the flow of QI-blood by warming the meridian, activating YANG and prormoting functioning of QI.
Stone gallbladder is natural or made aqueous sulfuric acid copper crystalline solid.Sour, pungent, cold.Removing the necrotic tissue; Removing toxic substances.
Composition principle: climacteric is dizzy belongs to a kind of more special dizzy.Pathogenesis is very complicated, and relevant with the vascular dysfunctions of cerebral circulation, some cases exists autonomic nervous dysfunction's situation.It is dizzy that the clinical common medicine with the common vertigo for the treatment of is treated climacteric.Chinese medicine adopts the medicine of suppressing the hyperactive liver and subsiding YANG or kidney tonifying, essence replenishing more, there is following defect but above therapeutic scheme treatment climacteric is dizzy: 1. dizzy with dizzy pathogenesis is not identical climacteric, climacteric is dizzy relevant with the vascular dysfunctions of cerebral circulation, time or vasospasm, cerebral tissue ischemia and sending out, time or excessive with vasodilation, brain perfusion increases suddenly relevant; 2. suppressing the hyperactive liver and subsiding YANG medicine, as Cornu Saigae Tataricae, Carapax Eretmochelydis, Ramulus Uncariae Cum Uncis, Concha Haliotidis, and relieving spasm by subduing liver-wind class medicine, as Rhizoma Gastrodiae, Bombyx Batryticatus, Scorpio, for climacteric dizzy card easily cause and exceed the proper limits in righting a wrong, cause brain hemoperfusion obstacle; 3. automatic regulation function dizzy and cerebral circulation is not normal relevant climacteric, and this point is not all paid close attention in Western medicine and Chinese medicine treatment.Therefore the object of the invention is: the 1. dual regulation of the side's of utilization Chinese medicine, the cerebrovascular of adjusting overdistension or excess shrinkage recovers; 2. reinvent the automatic regulation function of cerebral circulation; 3. protect the hemoperfusion of the heart, brain.
The present invention compared with the prior art, has following characteristics.
1, prescription uniqueness: the unbalance pathogenesis of automatic regulation function of dizzy cerebral circulation is started with for climacteric, and dredging collateral dispels the wind, suppressing the hyperactive liver relaxing muscles and tendons, assistant is with removing pathogenic heat from blood and toxic substance from the body.Prescription avoids using special blood circulation promoting medicine, as Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Radix Angelicae Sinensis, Flos Carthami etc., because said medicine is too moved blood, easily adds the risk of cerebral hemorrhage; Avoid using the medicine of suppressing the hyperactive liver to arrest the wind syndrome YANG hyperactivity suppressing, as Cornu Saigae Tataricae, Carapax Eretmochelydis, Ramulus Uncariae Cum Uncis, Concha Haliotidis, SHENGLONGMU, Concha Margaritifera, Magnetitum etc., its reason is such medicine sinking gesture weight, easily causes cerebral hyoperfusion, causes cerebral infarction.
2, get Retinervus Luffae Fructus, Pseudobulbus Cremastrae Seu Pleiones, Herba Sarcandrae three herbal medicines and share the merit that plays altogether dredging collateral side, and so-called dredging collateral, for medicine channels helps the meaning of its operation; Dredging collateral medicine has logical extremity channels, Tongxinluo, logical liver and gall network, logical spleen kidney network etc., and the Retinervus Luffae Fructus property of medicine is frivolous, walk women's head-ornaments and enter brain, and all right promoting blood circulation by removing wind of Retinervus Luffae Fructus, and Pseudobulbus Cremastrae Seu Pleiones sending up the lucid YANG the turbid descending the moon, although pharmacopeia is recorded its " heat-clearing and toxic substances removing; eliminating carbuncle eliminating stagnation ", inventor tests and shows for many years, and Pseudobulbus Cremastrae Seu Pleiones is for climacteric patient, cerebrovascular is had to two-way regulating function, and the cerebrovascular that can adjust overdistension or excess shrinkage recovers; Herba Sarcandrae clearing away heat and cooling blood, the speckle removing of invigorating blood circulation enters heart network, can effectively prevent the heart perfusion deficiency that excessive blood pressure lowering causes, and has reduced the risk of secondary heart infarction.
3, supplementary drug thing: Rhizoma Paridis heat-clearing and toxic substances removing is got by side, the in addition all right spasmolytic of this medicine; Fructus Chaenomelis suppressing the hyperactive liver relaxing muscles and tendons, can also alleviate cause because climacteric is dizzy nervous; Radix Inulae invigorating the spleen and regulating the stomach, promoting the flow of QI for relieving the stagnancy, can alleviate climacteric gastrointestinal symptoms; Herba Calystegiae Japonicae GUIXIN kidney channel, promoting blood circulation to remove obstruction in the collateral, can prevent heart, renal perfusion deficiency effectively.
4, using corrigent: the disease of hyperactivity of YANG due to deficiency of YIN is used Ramulus Cinnamomi promoting the flow of QI-blood by warming the meridian, and activating YANG and prormoting functioning of QI, belongs to using corrigent, this using corrigent, except activating yang network, also has the meaning of pregnant sun in the moon.
5, stone gallbladder is aqueous sulfuric acid copper crystalline solid, in we, uses, and is to separate out copper ion in its decoction process, experiment showed, that copper ion can increase our drug effect.
6, medicine material consumption of the present invention is groped in a large number to sum up through inventor and is drawn, each raw material consumption is for all to have good curative effect in following weight parts scope.
Detailed description of the invention
Below in conjunction with practical situation, the specific embodiment of the present invention is elaborated.
Embodiment 1, crude drug weight proportion: Retinervus Luffae Fructus 10g, Pseudobulbus Cremastrae Seu Pleiones 8g, Herba Sarcandrae 8g, Rhizoma Paridis 6g, Fructus Chaenomelis 6g, Radix Inulae 8g, Herba Calystegiae Japonicae 6g, Ramulus Cinnamomi 3g, stone gallbladder 3g.
Embodiment 2, crude drug weight proportion: Retinervus Luffae Fructus 20g, Pseudobulbus Cremastrae Seu Pleiones 15g, Herba Sarcandrae 15g, Rhizoma Paridis 10g, Fructus Chaenomelis 10g, Radix Inulae 15g, Herba Calystegiae Japonicae 10g, Ramulus Cinnamomi 6g, stone gallbladder 6g.
Embodiment 3, crude drug weight proportion: Retinervus Luffae Fructus 15g, Pseudobulbus Cremastrae Seu Pleiones 10g, Herba Sarcandrae 10g, Rhizoma Paridis 8g, Fructus Chaenomelis 8g, Radix Inulae 10g, Herba Calystegiae Japonicae 8g, Ramulus Cinnamomi 5g, stone gallbladder 5g.
When use, Chinese medicine Retinervus Luffae Fructus of the present invention, Pseudobulbus Cremastrae Seu Pleiones, Herba Sarcandrae, Rhizoma Paridis, Fructus Chaenomelis, Radix Inulae, Herba Calystegiae Japonicae, stone gallbladder, Ramulus Cinnamomi are decocted with water to twice, merging filtrate, a point morning and evening takes.Or make the dosage form such as oral liquid and use.
Effective combination of said medicine, coordinates mutually, can effectively reach dizzy object for the treatment of climacteric, and side effect is less.The above results is that clinical data fully proves, interrelated data is as follows, and wherein drugs use is the crude drug weight proportion in embodiment 3.
1 object and method.
1.1 objects: be that in January, a 2008 ~ 2011 year JIUYUE is made a definite diagnosis climacteric patients with vertigo 42 examples, patient all meets climacteric Diagnosis of Vertigo standard, and the equal nutriture of each case is good, and blood glucose, blood fat and hepatic and renal function are all in normal range.
1.2 method.
1.2.1 research method: 42 routine patients are divided into matched group 22 example and experimental group 20 examples at random, and it is oral that matched group gives blood-nourishing and brain-refreshing granules, vitamin B and oryzanol; Experimental group is adopting the embodiment of the present invention 3 gained extract orals.
1.2.2 safety evaluatio: all carry out the monitorings such as blood, urine, stool routine, liver, renal function, electrocardiogram before and after medication.
1.2.3 statistical analysis: carry out statistical analysis with SPSS 13.0, P<0.05 indicates significant.
2 results.
2.1 therapeutic evaluatioies: after treatment 7d, matched group total effective rate is 63.64%(14/22), treatment group total effective rate is 90.00%(18/20), two groups of comparisons, have obvious significant difference (P<0.05).
2.2 relapse rate comparisons: follow up a case by regular visits to half a year, half a year, internal reference group had 72.73%(16/22) Patients on Recurrence, and treatment group has 25.00%(5/20) Patients on Recurrence, two groups of comparisons, have obvious significant difference (P<0.01).
2.3 untoward reaction: two groups all do not occur obvious adverse reaction record.
3. conclusion.
This result of study prompting, the present invention treats climacteric and dizzyly has good effect and a higher feature of safety, clinic application, promotes.

Claims (2)

1. treat dizzy medicine of climacteric for one kind, it is characterized in that being processed by plurality of Chinese, its composition of raw materials and weight proportion are: 10 ~ 20 parts of Retinervus Luffae Fructuss, 8 ~ 15 parts of Pseudobulbus Cremastrae Seu Pleioness, 8 ~ 15 parts of Herba Sarcandraes, 6 ~ 10 parts of Rhizoma Paridis, 6 ~ 10 parts of Fructus Chaenomeliss, 8 ~ 15 parts of Radix Inulaes, 6 ~ 10 parts of Herba Calystegiae Japonicae, 3 ~ 6 parts of Ramulus Cinnamomi, 3 ~ 6 parts, stone gallbladder.
2. a kind of dizzy medicine of climacteric for the treatment of according to claim 1, is characterized in that its weight proportion is: 15 parts of Retinervus Luffae Fructuss, 10 parts of Pseudobulbus Cremastrae Seu Pleioness, 10 parts of Herba Sarcandraes, 8 parts of Rhizoma Paridis, 8 parts of Fructus Chaenomeliss, 10 parts of Radix Inulaes, 8 parts of Herba Calystegiae Japonicae, 5 parts of Ramulus Cinnamomi, 5 parts, stone gallbladder.
CN201210583644.9A 2012-12-31 2012-12-31 Medicine for treatment of menopause vertigo Expired - Fee Related CN103041171B (en)

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Publication number Priority date Publication date Assignee Title
CN102258703A (en) * 2011-09-09 2011-11-30 李海涛 Traditional Chinese medicine for treating vertigo

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102258703A (en) * 2011-09-09 2011-11-30 李海涛 Traditional Chinese medicine for treating vertigo

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
李德祥等.辨证治疗妇女更年期眩晕136例.《江苏中医》.1998,第19卷(第11期),28.
辨证治疗妇女更年期眩晕136例;李德祥等;《江苏中医》;19981231;第19卷(第11期);28 *

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