CN104383221A - Wet tissue additive solution for stopping itching and eliminating swelling after mosquito bites - Google Patents
Wet tissue additive solution for stopping itching and eliminating swelling after mosquito bites Download PDFInfo
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses a wet tissue additive solution for stopping itching and eliminating swelling after mosquito bites, and relates to the technical field of wet tissue production. The wet tissue additive solution is prepared from the following raw materials in parts by mass: 50-60 parts of aloe extractive, 40-50 parts of purslane extractive, 30-35 parts of garlic extractive, 15-20 parts of almond oil, 15-20 parts of lemon oil, 10-20 parts of lavender oil, 10-20 parts of eucalyptus oil, 25-35 parts of chlorophytum leaves, 20-30 parts of white pepper, 20-30 parts of paris polyphylla, 15-20 parts of clove, 15-20 parts of menthol, 20-25 parts of jasmine flower, 10-15 parts of shaddock peel, 5-10 parts of cape jasmine, 5-10 parts of calamine and 5-10 parts of herba siegesbeckiae. The wet tissue additive solution is free of any side effect on a human body, has a small irritating smell, can quickly stop itching and eliminate swelling after the mosquito bites, can prevent the mosquito bites once again, and has a good therapeutic effect.
Description
Technical field:
The present invention relates to wet tissue production technical field, be specifically related to a kind of wet tissue annex solution for relieving itching and eliminating swelling after mosquito bite.
Background technology:
In the summer of sweltering heat, mosquito is more, and people keep away in daily life unavoidably by mosquito bite.Bearing a pretty, delicate skin of infant is the main invasion object of mosquito, the skin after biting there will be red, swollen, bitterly, the symptom such as to itch, brought great puzzlement.Although commercially available floral water class medicine has anophelifuge, the effect such as antipruritic, to the alleviation after mosquito bite and skin restitution little.
Summary of the invention:
Technical problem to be solved by this invention is that providing a kind of is that main component, preparation technology are simply for the wet tissue annex solution of relieving itching and eliminating swelling after mosquito bite with natural Chinese medicinal herb.
Technical problem to be solved by this invention adopts following technical scheme to realize:
For a wet tissue annex solution for relieving itching and eliminating swelling after mosquito bite, be made up of the raw material of following mass fraction:
Aloe extract 50-60 part, Herba portulacae extract 40-50 part, Bulbus Allii extract 30-35 part, almond oil 15-20 part, Fructus Citri Limoniae oil 15-20 part, Oleum lavandula angustifolia 10-20 part, eucalyptus oil 10-20 part, bracketplant leaf 25-35 part, Radix orixae japonicae 20-30 part, Rhizoma Paridis 20-30 part, Flos Caryophylli 15-20 part, Mentholum 15-20 part, Flos Jasmini Sambac 20-25 part, pomelo peel 10-15 part, Fructus Gardeniae 5-10 part, Calamina 5-10 Fen, Herba Siegesbeckiae 5-10 part.
For a preparation method for the wet tissue annex solution of relieving itching and eliminating swelling after mosquito bite, comprise the steps:
(1) dry after first whole medical material being cleaned, in proportion Radix orixae japonicae, Rhizoma Paridis, Flos Caryophylli, Flos Jasmini Sambac and Fructus Gardeniae are joined in ultrasonic extraction tank, then the ethanol that volumetric concentration is 80%-90% is added, through three supersound extraction, filtration, merging filtrate;
(2) filtrate decompression Distillation recovery ethanol to purity step (1) prepared is 60%-65%, and after leaving standstill 12-24h subsequently, filtering precipitates and obtains medicinal liquid I;
(3) in proportion bracketplant leaf, pomelo peel, Calamina He Herba Siegesbeckiae are joined in multi-function extractor, add the pure water higher than medical material surface 3-5cm simultaneously, fluidized state is heated to after soaking 30-60min, keep 60-90min, filter liquor after being cooled to 30-40 DEG C subsequently, namely filtrate obtain medicinal liquid II after being concentrated into half volume;
(4) medicinal liquid I and medicinal liquid II is joined in mixer, then Aloe extract, Herba portulacae extract, Bulbus Allii extract, almond oil, Fructus Citri Limoniae oil, Oleum lavandula angustifolia, eucalyptus oil and Mentholum is added in proportion, mixture is fully uniformly mixed after being warming up to 50-60 DEG C, cools, lower the temperature and obtain target annex solution after mix homogeneously.
The weight ratio of described step (1) Chinese crude drug and ethanol is 1:10-20.
In described step (1), the operating temperature of ultrasonic extraction tank is room temperature, and operating frequency is 40KW, and each extraction time is 30-45min.
Described annex solution needs to carry out radiation sterilization before using.
The invention has the beneficial effects as follows: the present invention take natural Chinese medicinal herb as primary raw material, extract obtained annex solution without any side effects to human body, penetrating odor is little, can carry out relieving itching and eliminating swelling fast to the affected part after mosquito bite, and can prevent again biting of mosquito, therapeutic effect is good; And preparation method simply, farthest extracts the effective ingredient in Chinese herbal medicine, reduces production cost, good economy performance.
Detailed description of the invention:
The technological means realized to make the present invention, creation characteristic, reaching object and effect is easy to understand, below in conjunction with specific embodiment, setting forth the present invention further.
Embodiment 1
For a wet tissue annex solution for relieving itching and eliminating swelling after mosquito bite, be made up of the raw material of following mass fraction: Aloe extract 50 parts, Herba portulacae extract 40 parts, Bulbus Allii extract 30 parts, almond oil 15 parts, Fructus Citri Limoniae oil 15 parts, Oleum lavandula angustifolia 10 parts, eucalyptus oil 10 parts, 25 parts, bracketplant leaf, Radix orixae japonicae 20 parts, Rhizoma Paridis 20 parts, Flos Caryophylli 15 parts, Mentholum 15 parts, Flos Jasmini Sambac 20 parts, pomelo peel 10 parts, Fructus Gardeniae 5 parts, Calamina 5 Fen, Herba Siegesbeckiae 5 parts.
According to the wet tissue annex solution of above-mentioned formula for the preparation of relieving itching and eliminating swelling after mosquito bite, comprise the steps:
(1) dry after first whole medical material being cleaned, in proportion Radix orixae japonicae, Rhizoma Paridis, Flos Caryophylli, Flos Jasmini Sambac and Fructus Gardeniae are joined in ultrasonic extraction tank, then the ethanol that volumetric concentration is 80%-90% is added, through three supersound extraction, filtration, merging filtrate, the weight ratio of its Chinese crude drug and ethanol is 1:15, and the operating temperature of ultrasonic extraction tank is room temperature, operating frequency is 40KW, and each extraction time is 45min;
(2) filtrate decompression Distillation recovery ethanol to purity step (1) prepared is 60%-65%, and after leaving standstill 12-24h subsequently, filtering precipitates and obtains medicinal liquid I;
(3) in proportion bracketplant leaf, pomelo peel, Calamina He Herba Siegesbeckiae are joined in multi-function extractor, add the pure water higher than medical material surface 3-5cm simultaneously, fluidized state is heated to after soaking 30-60min, keep 60-90min, filter liquor after being cooled to 30-40 DEG C subsequently, namely filtrate obtain medicinal liquid II after being concentrated into half volume;
(4) medicinal liquid I and medicinal liquid II is joined in mixer, then Aloe extract, Herba portulacae extract, Bulbus Allii extract, almond oil, Fructus Citri Limoniae oil, Oleum lavandula angustifolia, eucalyptus oil and Mentholum is added in proportion, mixture is fully uniformly mixed after being warming up to 50-60 DEG C, cools, lower the temperature and obtain target annex solution after mix homogeneously.
It should be noted that annex solution will carry out radiation sterilization before using.
Embodiment 2
For a wet tissue annex solution for relieving itching and eliminating swelling after mosquito bite, be made up of the raw material of following mass fraction: Aloe extract 55 parts, Herba portulacae extract 45 parts, Bulbus Allii extract 35 parts, almond oil 20 parts, Fructus Citri Limoniae oil 15 parts, Oleum lavandula angustifolia 15 parts, eucalyptus oil 15 parts, 30 parts, bracketplant leaf, Radix orixae japonicae 25 parts, Rhizoma Paridis 25 parts, Flos Caryophylli 20 parts, Mentholum 15 parts, Flos Jasmini Sambac 20 parts, pomelo peel 12 parts, Fructus Gardeniae 8 parts, Calamina 7 Fen, Herba Siegesbeckiae 7 parts.
The wet tissue annex solution preparation method of the present embodiment is with embodiment 1.
Embodiment 3
For a wet tissue annex solution for relieving itching and eliminating swelling after mosquito bite, be made up of the raw material of following mass fraction: Aloe extract 60 parts, Herba portulacae extract 50 parts, Bulbus Allii extract 35 parts, almond oil 20 parts, Fructus Citri Limoniae oil 20 parts, Oleum lavandula angustifolia 20 parts, eucalyptus oil 20 parts, 35 parts, bracketplant leaf, Radix orixae japonicae 30 parts, Rhizoma Paridis 30 parts, Flos Caryophylli 20 parts, Mentholum 20 parts, Flos Jasmini Sambac 25 parts, pomelo peel 15 parts, Fructus Gardeniae 10 parts, Calamina 10 Fen, Herba Siegesbeckiae 10 parts.
The wet tissue annex solution preparation method of the present embodiment is with embodiment 1, and wherein the ultrasonic extraction time is 30min.
An intact skin irritant test: erythema and edema phenomenon all do not appear in experimental animal skin, one time intact skin irritant reaction top is " 0 ", belongs to nonirritant.
Skin allergy test: erythema and edema reaction all do not appear in experimental animal skin, and sensitization rate is 0%, by this wet tissue annex solution sensitization intensity of sensitization strength grading standard rating for having no skin allergic reaction.
Toxicity: be LD to chmice acute Oral toxicity
50>5000mg/kg BM, belongs to nontoxic level.
For illustrating that wet tissue annex solution of the present invention has good relieving itching and eliminating swelling effect to the affected part after mosquito bite, our company chooses the patient of 50 ages between 5 months-65 years old and tests, result of the test shows: evident in efficacy, the pastel delicate fragrance of abnormal smells from the patient, patient all can adapt to, without any untoward reaction, after using 3-5 time, all can fully recover in affected part, and can prevent mosquito again biting affected part.
More than show and describe ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.Application claims protection domain is defined by appending claims and equivalent thereof.
Claims (4)
1. for a wet tissue annex solution for relieving itching and eliminating swelling after mosquito bite, it is characterized in that, be made up of the raw material of following mass fraction:
Aloe extract 50-60 part, Herba portulacae extract 40-50 part, Bulbus Allii extract 30-35 part, almond oil 15-20 part, Fructus Citri Limoniae oil 15-20 part, Oleum lavandula angustifolia 10-20 part, eucalyptus oil 10-20 part, bracketplant leaf 25-35 part, Radix orixae japonicae 20-30 part, Rhizoma Paridis 20-30 part, Flos Caryophylli 15-20 part, Mentholum 15-20 part, Flos Jasmini Sambac 20-25 part, pomelo peel 10-15 part, Fructus Gardeniae 5-10 part, Calamina 5-10 Fen, Herba Siegesbeckiae 5-10 part.
2. a kind of wet tissue annex solution for relieving itching and eliminating swelling after mosquito bite according to claim 1, it is characterized in that, preparation method comprises the steps:
(1) dry after first whole medical material being cleaned, in proportion Radix orixae japonicae, Rhizoma Paridis, Flos Caryophylli, Flos Jasmini Sambac and Fructus Gardeniae are joined in ultrasonic extraction tank, then the ethanol that volumetric concentration is 80%-90% is added, through three supersound extraction, filtration, merging filtrate;
(2) filtrate decompression Distillation recovery ethanol to purity step (1) prepared is 60%-65%, and after leaving standstill 12-24h subsequently, filtering precipitates and obtains medicinal liquid I;
(3) in proportion bracketplant leaf, pomelo peel, Calamina He Herba Siegesbeckiae are joined in multi-function extractor, add the pure water higher than medical material surface 3-5cm simultaneously, fluidized state is heated to after soaking 30-60min, keep 60-90min, filter liquor after being cooled to 30-40 DEG C subsequently, namely filtrate obtain medicinal liquid II after being concentrated into half volume;
(4) medicinal liquid I and medicinal liquid II is joined in mixer, then Aloe extract, Herba portulacae extract, Bulbus Allii extract, almond oil, Fructus Citri Limoniae oil, Oleum lavandula angustifolia, eucalyptus oil and Mentholum is added in proportion, mixture is fully uniformly mixed after being warming up to 50-60 DEG C, cools, lower the temperature and obtain target annex solution after mix homogeneously.
3. the preparation method of a kind of wet tissue annex solution for relieving itching and eliminating swelling after mosquito bite according to claim 2, it is characterized in that: the weight ratio of described step (1) Chinese crude drug and ethanol is 1:10-20, the operating temperature of ultrasonic extraction tank is room temperature, operating frequency is 40KW, and each extraction time is 30-45min.
4. the preparation method of a kind of wet tissue annex solution for relieving itching and eliminating swelling after mosquito bite according to claim 2, is characterized in that: described annex solution needs to carry out radiation sterilization before using.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410577347.2A CN104383221A (en) | 2014-10-24 | 2014-10-24 | Wet tissue additive solution for stopping itching and eliminating swelling after mosquito bites |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410577347.2A CN104383221A (en) | 2014-10-24 | 2014-10-24 | Wet tissue additive solution for stopping itching and eliminating swelling after mosquito bites |
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| Publication Number | Publication Date |
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| CN104383221A true CN104383221A (en) | 2015-03-04 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410577347.2A Pending CN104383221A (en) | 2014-10-24 | 2014-10-24 | Wet tissue additive solution for stopping itching and eliminating swelling after mosquito bites |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104958516A (en) * | 2015-06-03 | 2015-10-07 | 刘强 | Detumescence and itching relieving liquid |
| CN111588672A (en) * | 2020-06-30 | 2020-08-28 | 河北农业大学 | Edible itching-relieving emulsion for mosquito bites and preparation method thereof |
-
2014
- 2014-10-24 CN CN201410577347.2A patent/CN104383221A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104958516A (en) * | 2015-06-03 | 2015-10-07 | 刘强 | Detumescence and itching relieving liquid |
| CN111588672A (en) * | 2020-06-30 | 2020-08-28 | 河北农业大学 | Edible itching-relieving emulsion for mosquito bites and preparation method thereof |
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Application publication date: 20150304 |