CN104383385A - Wet tissue additive solution for treating traumatic injuries and preparation method thereof - Google Patents
Wet tissue additive solution for treating traumatic injuries and preparation method thereof Download PDFInfo
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- CN104383385A CN104383385A CN201410577328.XA CN201410577328A CN104383385A CN 104383385 A CN104383385 A CN 104383385A CN 201410577328 A CN201410577328 A CN 201410577328A CN 104383385 A CN104383385 A CN 104383385A
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
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Abstract
The invention discloses a wet tissue additive solution for treating traumatic injuries and a preparation method thereof, and relates to the technical field of wet tissue production. The wet tissue additive solution is prepared from the following raw materials in parts by mass: 50-60 parts of curculigo sinensis, 40-50 parts of dipsacus asperoides, 30-40 parts of aconitum brachypodum, 30-40 parts of rhizoma drynariae, 30-40 parts of radix angelicae, 20-25 parts of reineckea herb, 20-30 parts of radix paeoniae rubra, 30-40 parts of frankincense, 15-30 parts of sangusis draconis, 10-20 parts of myrrh, 15-20 parts of artemisia anomala, 15-25 parts of muskmelon seeds, 20-30 parts of semen brassicae, 20-30 parts of radix zanthoxyli, 10-20 parts of moutan bark, 15-20 parts of rhizoma sparganii, 10-15 parts of ardisia quinquegona and 10-15 parts of mint. The wet tissue additive solution takes natural Chinese herbal components as raw materials, and effective components enter a body through skin, so that not only a role of local treatment can be played, but also an aim of systematic treatment can be achieved; the wet tissue additive solution takes effect fast, has no adverse reaction, and is convenient to carry about and use.
Description
Technical field:
The present invention relates to wet tissue production technical field, be specifically related to a kind of wet tissue annex solution being used for the treatment of traumatic injury and preparation method thereof.
Background technology:
Traumatic injury is a kind of burst disease of harmful to human.Along with socioeconomic fast development, the facility of commercial scale and traffic, sprains and the ratio of fracturing increases day by day, and affect the normal work of people, severe patient even can fall lifelong disability, makes troubles to patient, causes burden also to family and society.The main method of current treatment traumatic injury makes to fix the affected part of fracture patient, and by normal healing, doctor trained in Western medicine often adopts the methods such as reset, planter cast, Over-articular fixation in treatment, and patient suffering can be made large, and the course for the treatment of is long.Existing Chinese traditional treatment method is the method that employing resets, Chinese medicine for oral administration adds Dressed plaster, and its defect is that curative effect is slow, weak effect, and drug use is inconvenient, and containing noxious substance lead in Dressed plaster, easily causes skin allergy and human injury.
Summary of the invention:
Technical problem to be solved by this invention is to provide a kind of nonirritant, evident in efficacy and technique wet tissue annex solution being simply used for the treatment of traumatic injury and preparation method thereof.
Technical problem to be solved by this invention adopts following technical scheme to realize:
Be used for the treatment of a wet tissue annex solution for traumatic injury, be made up of the raw material of following mass fraction:
Rhizoma Curculiginis (processed with wine) 50-60 part, Radix Dipsaci 40-50 part, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 30-40 part, Rhizoma Drynariae 30-40 part, Radix Angelicae Dahuricae 30-40 part, Herba Reineckeae Carneae 20-25 part, Radix Paeoniae Rubra 20-30 part, Olibanum 30-40 part, Sanguis Draxonis 15-30 part, Myrrha 10-20 part, Herba Artemisiae Anomalae 15-20 part, Semen Melo 15-25 part, Semen Sinapis Albae 20-30 part, Radix Zanthoxyli 20-30 part, Cortex Moutan 10-20 part, Rhizoma Sparganii 15-20 part, DALUOSAN 10-15 part, Herba Menthae 10-15 part.
The described wet tissue annex solution being used for the treatment of traumatic injury is made up of the raw material of following mass fraction:
Rhizoma Curculiginis (processed with wine) 55 parts, Radix Dipsaci 45 parts, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 30 parts, Rhizoma Drynariae 35 parts, the Radix Angelicae Dahuricae 40 parts, Herba Reineckeae Carneae 22 parts, Radix Paeoniae Rubra 25 parts, Olibanum 30 parts, Sanguis Draxonis 25 parts, Myrrha 15 parts, Herba Artemisiae Anomalae 18 parts, Semen Melo 20 parts, Semen Sinapis Albae 25 parts, Radix Zanthoxyli 25 parts, Cortex Moutan 15 parts, Rhizoma Sparganii 18 parts, DALUOSAN 12 parts, Herba Menthae 15 parts.
Be used for the treatment of a preparation method for the wet tissue annex solution of traumatic injury, comprise the following steps:
(1) dry after all medical materials being cleaned, take Rhizoma Curculiginis (processed with wine), Radix Dipsaci, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Rhizoma Drynariae, Cortex Moutan and Rhizoma Sparganii in proportion, respectively by its dozen of powder, cross 40 mesh sieves, then by all medicated powder mixing after sieving;
(2) join in ultrasonic extraction tank by mixed powder, then add the ethanol that volumetric concentration is 85%-95%, through three supersound extraction, filter to get filtrate I;
(3) Testa Tritici is joined in medicine roasting machine, fry and add the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Semen Melo and Semen Sinapis Albae in proportion to when playing cigarette, fry to all medical materials loose in yellow or buff, after being cooled to 30-40 DEG C, screen out Testa Tritici;
(4) medical material processed through step (3) is joined in extraction pot, and the pure water added higher than medical material surface 5-10cm, be heated to fluidized state after soaking 60-90min, keep 60-90min, be cooled to 30-40 DEG C subsequently, filter to get filtrate II;
(5) Herba Reineckeae Carneae, Herba Artemisiae Anomalae, Olibanum, Sanguis Draxonis, Myrrha, Radix Zanthoxyli, DALUOSAN and Herba Menthae is taken in proportion, joined in extraction pot, and the pure water added higher than medical material surface 5-10cm, fluidized state is heated to after soaking 60-90min, keep 90-120min, be cooled to 30-40 DEG C subsequently, filter to get filtrate III;
(6) filtrate I, filtrate II and filtrate II I are joined in mixer, stirred at ambient temperature, after abundant mix homogeneously, obtain annex solution.
The amount ratio of described step (2) Chinese crude drug and ethanol is 1:10-15.
The invention has the beneficial effects as follows: the present invention adopts natural Chinese medicinal herb composition to be raw material, the obtained wet tissue with treatment traumatic injury effect, active ingredient enters health through skin, can play local therapeutic effects, can reach again the object for the treatment of whole body; Onset speed is fast, has no untoward reaction, and carries with easy to use.
Detailed description of the invention:
The technological means realized to make the present invention, creation characteristic, reaching object and effect is easy to understand, below in conjunction with specific embodiment, setting forth the present invention further.
Embodiment 1:
Be used for the treatment of a wet tissue annex solution for traumatic injury, be made up of the raw material of following mass fraction: Rhizoma Curculiginis (processed with wine) 50 parts, Radix Dipsaci 40 parts, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 30 parts, Rhizoma Drynariae 30 parts, the Radix Angelicae Dahuricae 30 parts, Herba Reineckeae Carneae 20 parts, Radix Paeoniae Rubra 20 parts, Olibanum 30 parts, Sanguis Draxonis 15 parts, Myrrha 10 parts, Herba Artemisiae Anomalae 15 parts, Semen Melo 15 parts, Semen Sinapis Albae 20 parts, Radix Zanthoxyli 20 parts, Cortex Moutan 10 parts, Rhizoma Sparganii 15 parts, DALUOSAN 10 parts, Herba Menthae 10 parts.
Carry out the preparation of wet tissue annex solution according to aforementioned proportion, concrete steps are as follows:
(1) dry after all medical materials being cleaned, take Rhizoma Curculiginis (processed with wine), Radix Dipsaci, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Rhizoma Drynariae, Cortex Moutan and Rhizoma Sparganii in proportion, respectively by its dozen of powder, cross 40 mesh sieves, then by all medicated powder mixing after sieving;
(2) join in ultrasonic extraction tank by mixed powder, then add the ethanol that volumetric concentration is 85%-95%, through three supersound extraction, filter to get filtrate I;
(3) Testa Tritici is joined in medicine roasting machine, fry and add the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Semen Melo and Semen Sinapis Albae in proportion to when playing cigarette, fry to all medical materials loose in yellow or buff, after being cooled to 30-40 DEG C, screen out Testa Tritici;
(4) medical material processed through step (3) is joined in extraction pot, and the pure water added higher than medical material surface 5-10cm, be heated to fluidized state after soaking 60-90min, keep 60-90min, be cooled to 30-40 DEG C subsequently, filter to get filtrate II;
(5) Herba Reineckeae Carneae, Herba Artemisiae Anomalae, Olibanum, Sanguis Draxonis, Myrrha, Radix Zanthoxyli, DALUOSAN and Herba Menthae is taken in proportion, joined in extraction pot, and the pure water added higher than medical material surface 5-10cm, fluidized state is heated to after soaking 60-90min, keep 90-120min, be cooled to 30-40 DEG C subsequently, filter to get filtrate III;
(6) filtrate I, filtrate II and filtrate II I are joined in mixer, stirred at ambient temperature, after abundant mix homogeneously, obtain annex solution.
Embodiment 2:
Be used for the treatment of a wet tissue annex solution for traumatic injury, be made up of the raw material of following mass fraction: Rhizoma Curculiginis (processed with wine) 55 parts, Radix Dipsaci 45 parts, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 30 parts, Rhizoma Drynariae 35 parts, the Radix Angelicae Dahuricae 40 parts, Herba Reineckeae Carneae 22 parts, Radix Paeoniae Rubra 25 parts, Olibanum 30 parts, Sanguis Draxonis 25 parts, Myrrha 15 parts, Herba Artemisiae Anomalae 18 parts, Semen Melo 20 parts, Semen Sinapis Albae 25 parts, Radix Zanthoxyli 25 parts, Cortex Moutan 15 parts, Rhizoma Sparganii 18 parts, DALUOSAN 12 parts, Herba Menthae 15 parts.
The preparation method of the present embodiment wet tissue annex solution is identical with embodiment 1.
Embodiment 3:
Be used for the treatment of a wet tissue annex solution for traumatic injury, be made up of the raw material of following mass fraction: Rhizoma Curculiginis (processed with wine) 60 parts, Radix Dipsaci 50 parts, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 40 parts, Rhizoma Drynariae 40 parts, the Radix Angelicae Dahuricae 40 parts, Herba Reineckeae Carneae 25 parts, Radix Paeoniae Rubra 30 parts, Olibanum 40 parts, Sanguis Draxonis 30 parts, Myrrha 20 parts, Herba Artemisiae Anomalae 20 parts, Semen Melo 25 parts, Semen Sinapis Albae 30 parts, Radix Zanthoxyli 30 parts, Cortex Moutan 20 parts, Rhizoma Sparganii 20 parts, DALUOSAN 15 parts, Herba Menthae 15 parts.
The preparation method of the present embodiment wet tissue annex solution is identical with embodiment 1.
Product of the present invention is carried out animal safety test:
An intact skin irritant test: erythema and edema phenomenon all do not appear in experimental animal skin, one time intact skin irritant reaction top is " 0 ", belongs to nonirritant.
Skin allergy test: erythema and edema reaction all do not appear in experimental animal skin, and sensitization rate is 0%, by this wet tissue annex solution sensitization intensity of sensitization strength grading standard rating for having no skin allergic reaction.
Toxicity: be LD to chmice acute Oral toxicity
50>5000mg/kgBM, belongs to nontoxic level.
For showing that wet tissue annex solution of the present invention is to the therapeutic effect of traumatic injury, the present inventor carries out clinical trial to 100 routine cases, wherein male 56 people, women 44 people, and the age is between 5-68 year.The wet tissue that the application of the invention annex solution is made, 96 people thoroughly cure, and cure rate reaches 96%.
More than show and describe ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.Application claims protection domain is defined by appending claims and equivalent thereof.
Claims (4)
1. be used for the treatment of a wet tissue annex solution for traumatic injury, it is characterized in that, be made up of the raw material of following mass fraction:
Rhizoma Curculiginis (processed with wine) 50-60 part, Radix Dipsaci 40-50 part, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 30-40 part, Rhizoma Drynariae 30-40 part, Radix Angelicae Dahuricae 30-40 part, Herba Reineckeae Carneae 20-25 part, Radix Paeoniae Rubra 20-30 part, Olibanum 30-40 part, Sanguis Draxonis 15-30 part, Myrrha 10-20 part, Herba Artemisiae Anomalae 15-20 part, Semen Melo 15-25 part, Semen Sinapis Albae 20-30 part, Radix Zanthoxyli 20-30 part, Cortex Moutan 10-20 part, Rhizoma Sparganii 15-20 part, DALUOSAN 10-15 part, Herba Menthae 10-15 part.
2. a kind of wet tissue annex solution being used for the treatment of traumatic injury according to claim 1, it is characterized in that, described in be used for the treatment of traumatic injury wet tissue annex solution be made up of the raw material of following mass fraction: Rhizoma Curculiginis (processed with wine) 55 parts, Radix Dipsaci 45 parts, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 30 parts, Rhizoma Drynariae 35 parts, the Radix Angelicae Dahuricae 40 parts, Herba Reineckeae Carneae 22 parts, Radix Paeoniae Rubra 25 parts, Olibanum 30 parts, Sanguis Draxonis 25 parts, Myrrha 15 parts, Herba Artemisiae Anomalae 18 parts, Semen Melo 20 parts, Semen Sinapis Albae 25 parts, Radix Zanthoxyli 25 parts, Cortex Moutan 15 parts, Rhizoma Sparganii 18 parts, DALUOSAN 12 parts, Herba Menthae 15 parts.
3. be used for the treatment of a preparation method for the wet tissue annex solution of traumatic injury, it is characterized in that, comprise the following steps:
(1) dry after all medical materials being cleaned, take 50-60 part Rhizoma Curculiginis (processed with wine), 40-50 part Radix Dipsaci, 30-40 part Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), 30-40 part Rhizoma Drynariae, 10-20 part Cortex Moutan and 15-20 part Rhizoma Sparganii, respectively by its dozen of powder, cross 40 mesh sieves, then by all medicated powder mixing after sieving;
(2) join in ultrasonic extraction tank by mixed powder, then add the ethanol that volumetric concentration is 85%-95%, through three supersound extraction, filter to get filtrate I;
(3) Testa Tritici is joined in medicine roasting machine, fry and add 30-40 part Radix Angelicae Dahuricae, 20-30 part Radix Paeoniae Rubra, 15-25 part Semen Melo and 20-30 part Semen Sinapis Albae in proportion to when playing cigarette, fry to all medical materials loose in yellow or buff, after being cooled to 30-40 DEG C, screen out Testa Tritici;
(4) medical material processed through step (3) is joined in extraction pot, and the pure water added higher than medical material surface 5-10cm, be heated to fluidized state after soaking 60-90min, keep 60-90min, be cooled to 30-40 DEG C subsequently, filter to get filtrate II;
(5) 20-25 part Herba Reineckeae Carneae, 15-20 part Herba Artemisiae Anomalae, 30-40 part Olibanum, 15-30 part Sanguis Draxonis, 10-20 part Myrrha, 20-30 part Radix Zanthoxyli, 10-15 part DALUOSAN and 10-15 part Herba Menthae is taken in proportion, joined in extraction pot, and the pure water added higher than medical material surface 5-10cm, fluidized state is heated to after soaking 60-90min, keep 90-120min, be cooled to 30-40 DEG C subsequently, filter to get filtrate III;
(6) filtrate I, filtrate II and filtrate II I are joined in mixer, stirred at ambient temperature, after abundant mix homogeneously, obtain annex solution.
4. a kind of preparation method being used for the treatment of the wet tissue annex solution of traumatic injury according to claim 3, is characterized in that: the amount ratio of described step (2) Chinese crude drug and ethanol is 1:10-15.
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