DK201600379A1

DK201600379A1 - Detumescence Odynolysis Ointment

Info

Publication number: DK201600379A1
Application number: DKPA201600379A
Authority: DK
Inventors: Xiaoying Liu
Original assignee: Tingen Tech Co Ltd
Priority date: 2015-11-02
Filing date: 2016-06-24
Publication date: 2017-05-15
Also published as: DE102016002122A1; KR20170051126A

Description

DETUMESCENCE ODYNOLYSIS OINTMENT TECHNICAL FIELD

The present invention discloses a detumescence odynolysis ointment. BACKGROUND

Chinese medicine treatment of traumatic injury has several thousands of years of history. The traumatic injury usually refers to soft tissue injury caused by external force action or overexerting in the case of improper posture, and is expressed as swelling and pain. In the field of traditional Chinese medicine, all of muscle and bone injury, ecchymoma, vital energy and blood at odds, main and collateral channels blocking, and visceral organ damage are uniformly called traumatic injury. In the prior art, a fuming and washing medical composition prepared from Angelica sinensis, Panax notoginseng, flos carthami, Radix Paeoniae Alba, Radix Achyranthis Bidentatae, myrrh, frankincense and trogopterus dung, is selected for treatment, which has the effect in promoting circulation and removing stasis, relieving pain and eliminating swelling; but it is only palliative. When the traumatic injury just occurs, patients often suffer from unbearable pain, and hope to adopt some effective treatment methods to relieve pain, so they tend to use fuming and washing medicine to perform fuming and washing immediately, this behavior easily results in intensive dilation of blood vessel in the wounded part, to thereby aggravate errhysis and edema, which not only will lead to soft tissue adhesion and partial function weakening, but also easily aggravate pain feeling. Existing correct behavior of cold compress can cause vasoconstriction in the wounded part, and reduce bleeding, swelling and pain, however, its alleviation capacity is limited, the patients still have to endure severe pain, resulting in inconvenience for the normal physical activities.

Therefore, it is necessary to develop a detumescence odynolysis ointment which can be used immediately when traumatic injury just occurs, to relieve pain in time, promote vasoconstriction and further inhibit the occurrence of bleeding and swelling.

SUMMARY OF THE INVENTION

The present invention aims at providing a detumescence odynolysis ointment having good comprehensive pharmaceutical property and good treatment effect, and prepared by taking dog leg bone as main raw material, and combining the effects of traditional medicinal materials and research achievements of modem pharmacology.

For this purpose, the present invention discloses a detumescence odynolysis ointment, comprising by weight parts: dog leg bone 20-35, ground beetle 10-15, goat blood 6-10, menthol 4-8, Semen Brassicae 4-8, frankincense 1-3, cinnabar 1-3, Sanguinem Draconis 1-3, and honey 3-5.

According to one embodiment of the present invention, the detumescence odynolysis ointment comprises by weight parts: dog leg-bone 21, ground beetle 11, goat blood 6, menthol 5, Semen Brassicae 5, frankincense 1, cinnabar 1, Sanguinem Draconis 1, and honey 3.

According to one embodiment of the present invention, the detumescence odynolysis ointment comprises by weight parts: dog leg-bone 26, ground beetle 12, goat blood 7, menthol 6, Semen Brassicae 5, frankincense 2, cinnabar 1, Sanguinem Draconis 2, and honey 4.

According to one embodiment of the present invention, the detumescence odynolysis ointment comprises by weight parts: dog leg- bone 33, ground beetle 14, goat blood 8, menthol 7, Semen Brassicae 6, frankincense 2, cinnabar 2, Sanguinem Draconis 2, and honey 5.

According to one embodiment of the present invention, the detumescence odynolysis ointment further comprises by weight parts: akebiaquinata 3-8.

The above detumescence odynolysis ointment is prepared and administrated as follows : weighing all of the raw materials according to their weight parts, mixing and grinding the same to obtain a paste; weighing appropriate amounts of sesame oil and yellow lead, and decocting the same to obtain a black factice; weighing 5kg of the black factice, gently heating it to melt, adding 1.5kg of the ground Chinese medicine paste, and uniformly stirring; spreading 20-30g of the Chinese medicine ointment on a soft cloth, and pasting it at the swelling and pain position, replaced once for every day, and a treatment course of 5 times of administration.

The raw materials of detumescence odynolysis ointment have the pharmacological performances as follows:

Dog leg-bone: The bone of Canidae animal-dog, has solid sclerotin, not very heavy weight, color of white or pale yellow, not even cross section, and not obvious inner net-like medulla. After a dog is killed, the muscles on its bone is removed, and the bone is air dried in a place with good ventilation; the bone cannot be solarized, to avoid oil leaking and color changing. It has the effect in tonifying spleen and main and collateral channels, invigorating the circulation of blood, and promote tissue regeneration.

Ground beetle (name from traditional Chinese medicine): The dried body of female insect of the family Corydiidae Eupolyphaga Sinensis

Walker or Steleophaga Plancyi (Boleny). After the female insect is caught, it is scalded in boiling water to die, and then followed by drying in the sun or stove drying. It is distributed in Hebei, Shanxi, Gansu, Qinghai, Shandong, Henan, Jiangsu, Zhejiang, Hunan, etc. It has the effect in breaking blood and removing stasis, and promoting reunion of fractured bones; and is used for the treatment of traumatic injury, injury of tendon and muscle, fracture, blood stasis and amenorrhea, postpartum stasis and stomachache, and lump in the abdomen.

Goat blood: its preparation method is recorded in “YUE XI OU JI”, “BEN JING FENG YUAN”, and “GANG MU SHI ΥΓ of Chinese document “BEN CAO HUI YAN”.

Menthol: is a chemical medicine, extracted from the leaf and stem of mint, white crystal, and main ingredient of mint essential oil, and has molecular formula of C10H20O. In the world, India is a major producer of natural mint. Both menthol and racemic menthol can be used as an odorant of toothpaste, perfume, drink and candy. In medicine, it can be applied to the skin or mucosa as stimulating drug, to exert the effects of refreshing and relieving itching; it can also be taken orally as carminative medicine for headache, rhinitis, pharyngitis and laryngitis. The ester thereof is used for perfume and medicine.

Semen Brassicae: Latin name of Semen sinapis. It is dried matured seed of annual or biennial plant-Sinapis alba L.in Brassicaceae. It has spherical shape, off-white or pale yellow surface, thin and crisp seed coat, oiliness, odorless smell, bitter taste, and can be used as medicine. It is mainly produced in Anhui, Henan, Sichuan, Shandong, etc., and cultivated in various places of China.

Frankincense: traditional Chinese medicine name, is a resin exudated from the bark of Boswellia carterii Birdw. in Burseraceae and congener plant- Boswellia bhaurdajiana Birdw. It is classified into Somalian frankincense and Ethiopian frankincense, each being classified into frankincense bead and original frankincense.

Cinnabar: has many aliases such as vermillion, is a natural ore of mercuric sulfide (HgS), bright red, has adamantine luster or metallic luster, and belongs to trigonal system. The main ingredient of the cinnabar is mercuric sulfide, but usually mixed up with realgar, apatite, asphaltene, etc. The sedative and hypnotic effect of the cinnabar have not been confirmed. It does have detoxifying effect and preservative effect, can inhibit or kill skin bacteria and parasite. It is a compound of mercury, which has special affinity with mercapto in proteins and can inhibit various enzymes and activities at high concentration. After entering into the human body, mercury is mainly distributed in the liver and kidney, to thereby cause liver and kidney damage; it also can pass through the blood-brain barrier, and directly damage the central nervous system.

Sanguinem Draconis: (name from traditional Chinese medicine), is prepared by processing resin exudated from the fruit of Arecaceae plant-Daemonorop draco. It is distributed in Indonesia, Java, Sumatra, Borneo, etc.; has the effect in invigorating the circulation of blood and relieving pain, dispersing blood stasis and stop bleeding, promoting tissue regeneration and astringing ulcer; and can be used for the treatment of traumatic injury, heart and abdomen blood pain, traumatic bleeding, no astringing of swelling and ulcer on the body surface.

Honey: brewed in honeycomb in which nectar collected from flowers of bloomer by bee is located.

Akebiaquinata (name from traditional Chinese medicine): is a dried rattan of Lardizabalaceae plant-Akebia quinata (Thunb.) Decne., Akebia tri-foliata (Thunb.) Koidz., or Akebia tri-foliata (Thunb.) Koidz.; or

Australis (Diels) Rehd. It is harvested in autumn, and prepared by cutting to obtain a stem part, removing withes and drying in the shade.

The detumescence odynolysis ointment provided in the present invention has special effects for sprain, contusion, fracture, nonunion, difficult joint bending after plaster immobilization or operation, waist sprain, sprained ankle, ischialgia, ligamentous injury, pulled muscle, tendon injury, meniscus injury and soft tissue injury.

Other features and advantages of the present invention will be described in detail in a subsequent section of the specific embodiments.

DETAILED DESCRIPTION OF THE EMBODIMENTS

The present invention provides many applicable inventive concepts, which can be widely embodied in the specific context. Specific examples described in the following embodiments of the present invention are only as exemplary illustrations for the specific implementation of the present invention, and are not constructed to limit the scope of the present invention.

Without loss of generality, the present invention discloses a detumescence odynolysis ointment, comprising by weight parts: dog leg bone 20-35, ground beetle 10-15, goat blood 6-10, menthol 4-8, Semen Brassicae 4-8, frankincense 1-3, cinnabar 1-3, Sanguinem Draconis 1-3, and honey 3-5.

Wherein, all the above raw materials can be commercially available finished products, and also can be obtained with common preparation method, for example, can be prepared by drying and pulverizing crude materials into commonly-used powder in the art. The drying method can be baking or naturally drying, and preferably naturally drying. The pulverizing method can be a commonly-used method in the field of traditional Chinese medicine, and the average particle size of the pulverized materials is preferably 20-30 mesh, and more preferably 20 mesh.

For further implementing above technical solution, the preparation method and administration method of above detumescence odynolysis ointment are as follows: weighing all of the raw materials according to their weight parts, mixing and grinding the same to obtain a paste; weighing appropriate amounts of sesame oil and yellow lead, and decocting the same to obtain a black factice; weighing 5kg of the black factice, gently heating it to melt, adding 1.5kg of the ground Chinese medicine paste, and uniformly stirring; spreading 20-30g of the Chinese medicine ointment on a soft cloth, and pasting it at the swelling and pain position, replaced once for every day, and a treatment course of 5 times of administration.

It should be noted that since the production process of above black factice belongs to the prior art, the relevant details thereof are not described herein. The present invention only utilizes the glutinousness of the black factice to adhere the ointment at swelling and pain position.

One day of administration of above detumescence odynolysis ointment can produce the desired result, two days of administration thereof can remarkably alleviate the symptom, two courses of treatment can allow a patient to recover capacity for action, and four courses of treatment can allow a patient to recover to health.

Below, the present invention will be described in more detail through the examples.

Examples 1-5

Examples 1-5 are used to illustrate the detumescence odynolysis ointment provided in the present invention.

According to the weight parts listed in Table 1, detumescence odynolysis ointments 1-5 are obtained.

Table 1

Experimental examples 1-5

Experimental examples 1-5 are used to illustrate the treatment effect of the Detumescence odynolysis ointment provided in the present invention. (1) The alleviation effect for sprain and contusion 150 male and female patients (in the age range of 30-70) with the sprain and contusion at different degrees are selected, and randomly divided into five groups, with 30 patients in each group. The Detumescence odynolysis ointments 1-5 are used in the five groups, respectively. For administration, the Detumescence odynolysis ointment is pasted at the injury positions (replaced once a day, a treatment course of 5 times), and after 4 courses of treatment, the effects are observed, wherein compared with a condition before administration, the patient whose symptom completely disappears is marked as o, the patient whose symptom is remarkably alleviated is marked as Δ, and the patient whose symptom has no remarkable alleviation is marked as x, and the treatment effects are shown in Table 2.

Table 2

(2) The alleviation effect for fracture, nonunion, difficult joint bending after plaster immobilization or operation 150 male and female patients (in the age range of 35-65) with above symptoms at different degrees are selected, and randomly divided into five groups, with 30 patients in each group. The Detumescence odynolysis ointments 1-5 are used in the five groups, respectively. For administration, the Detumescence odynolysis ointment is pasted at the injury positions (replaced once a day, a treatment course of 5 times), and after 4 courses of treatment, the effects are observed, wherein compared with a condition before administration, the patient whose symptom completely disappears is marked as o, the patient whose symptom is remarkably alleviated is marked as Δ, and the patient whose symptom has no remarkable alleviation is marked as x, and the treatment effects are shown in Table 3.

Table 3

(3) The alleviation effect for waist sprain, sprained ankle, ischialgia, ligamentous injury, pulled muscle, tendon injury, meniscus injury and soft tissue injury 150 male and female patients (in the age range of 55-70) with above symptoms at different degrees are selected, and randomly divided into five groups, with 30 patients in each group. The Detumescence odynolysis ointments 1-5 are used in the five groups, respectively. For administration, the Detumescence odynolysis ointment is pasted at the injury positions (replaced once a day, a treatment course of 5 times), and after 4 courses of treatment, the effects are observed, wherein compared with a condition before administration, the patient whose symptom completely disappears is marked as o, the patient whose symptom is remarkably alleviated is marked as Δ, and the patient whose symptom has no remarkable alleviation is marked as x, and the treatment effects are shown in Table 4.

Table 4

It can be seen from above test results of the test examples that: the detumescence odynolysis ointment provided in the present invention has special effects for sprain, contusion, fracture, nonunion, difficult joint bending after plaster immobilization or operation, waist sprain, sprained ankle, ischialgia, ligamentous injury, pulled muscle, tendon injury, meniscus injury and soft tissue injury.

Claims

1. A detumescence odynolysis ointment, comprising by weight parts: dog leg-bone 20-35, ground beetle 10-15, goat blood 6-10, menthol 4-8, Semen Brassicae 4-8, frankincense 1-3, cinnabar 1-3, Sanguinem Draconis 1-3, and honey 3- 5.

2. The detumescence odynolysis ointment according to claim 1, comprising by weight parts: dog leg-bone 21, ground beetle 11, goat blood 6, menthol 5, Semen Brassicae 5, frankincense 1, cinnabar 1, Sanguinem Draconis 1, and honey 3.

3. The detumescence odynolysis ointment according to claim 1, comprising by weight parts: dog leg-bone 26, ground beetle 12, goat blood 7, menthol 6, Semen Brassicae 5, frankincense 2, cinnabar 1, Sanguinem Draconis 2, and honey 4.

4. The detumescence odynolysis ointment according to claim 1, comprising by weight parts: dog leg-bone 33, ground beetle 14, goat blood 8, menthol 7, Semen Brassicae 6, frankincense 2, cinnabar 2, Sanguinem Draconis 2, and honey 5.

5. The detumescence odynolysis ointment according to any one of claims 1-4, further comprising by weight parts: akebiaquinata 3-8.