CN108392445B - Herbal antipruritic lotion - Google Patents

Herbal antipruritic lotion Download PDF

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CN108392445B
CN108392445B CN201810311446.4A CN201810311446A CN108392445B CN 108392445 B CN108392445 B CN 108392445B CN 201810311446 A CN201810311446 A CN 201810311446A CN 108392445 B CN108392445 B CN 108392445B
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extract
herbal
borneol
phenoxyethanol
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CN108392445A (en
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Zhang Fumu
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Chengdu Shuhetai Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q13/00Formulations or additives for perfume preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/02Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
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  • Pest Control & Pesticides (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Chemical & Material Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
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  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses herbal antipruritic liquid which comprises the following raw materials in parts by weight: 15-25 parts of perilla extract, 15-25 parts of purslane extract, 5-15 parts of forsythia extract, 5-15 parts of gardenia extract, 5-15 parts of chamomile extract, 10-40 parts of alcohol, 1-4 parts of borneol, 1-5 parts of levomenthol and 0.2-1 part of phenoxyethanol. The invention is a pure herbal essence formula, natural herbal stock solution does not contain allergic and irritant components such as essence, camphor and the like, is mild and natural, has fragrant smell, quickly relieves discomfort caused by mosquito bites, relieves itching and protects the skin.

Description

Herbal antipruritic lotion
Technical Field
The invention relates to the field of cosmetics, and discloses herbal antipruritic lotion.
Background
Mosquito bites have plagued people's lives and can transmit diseases such as malaria, filariasis, epidemic encephalitis B, dengue fever and the like, causing serious public health problems.
At present, a plurality of mosquito repelling products such as mosquito coils, mosquito repelling toilet water, mosquito repelling liquid, mosquito repelling bracelets and the like are available in the market, the mosquito repelling work is better, but the phenomenon of mosquito biting can be avoided.
Itching relieving and swelling eliminating after mosquito bites in summer, the traditional domestic products comprise cooling oil, essential balm, Liushen toilet water, electrodeless paste (containing hormone) and other products, the cooling feeling is very sufficient, but the itching relieving and swelling eliminating effects are not ideal; foreign products including Japanese dripless, American radix Lithospermi cream, Australia papaya cream, Youxielin all-purpose cream, etc. have good effects, but are high in price.
Disclosure of Invention
Based on the above, there is a need for a herbal antipruritic lotion, which adopts a pure herbal essence formula, contains no allergic and irritant components such as essence and camphor, is mild and natural, has a fragrant smell, quickly relieves discomfort caused by mosquito bites, and has the effects of relieving itching and protecting skin.
The technical scheme of the invention is as follows:
the herbal antipruritic lotion comprises the following raw materials in parts by weight: 15-25 parts of perilla extract, 15-25 parts of purslane extract, 5-15 parts of forsythia extract, 5-15 parts of gardenia extract, 5-15 parts of chamomile extract, 10-40 parts of alcohol, 1-4 parts of borneol, 1-5 parts of levomenthol and 0.2-1 part of phenoxyethanol.
Preferably, the raw materials comprise perilla extract, purslane extractive, forsythia extractive, gardenia extractive, chamomile extractive, alcohol, borneol, levomenthol and phenoxyethanol, and the formula ratio by weight is as follows: 18-22 parts of perilla extract, 18-22 parts of purslane extract, 8-12 parts of forsythia extract, 8-12 parts of gardenia extract, 8-12 parts of chamomile extract, 28-32 parts of alcohol, 1-2 parts of borneol, 1-2 parts of levomenthol and 0.5-1 part of phenoxyethanol.
In the technical scheme, the herbal antipruritic lotion is prepared by mixing and stirring perilla extract, purslane extractive, forsythia extractive, gardenia extractive, chamomile extractive, alcohol, borneol, levomenthol and phenoxyethanol; wherein:
the perilla mainly contains volatile components such as perillaldehyde and limonene and flavonoid compounds such as perillarin, luteolin, apigenin and apigenin, can resist oxygen free radicals and superoxide anions, and has an anti-aging effect; if it is bitten by mosquito, fresh folium Perillae can be mashed and applied with the composition for relieving pain and itching.
Purslane, also called Wuxing grass, Changming vegetable and the like, is rich in a large amount of compounds such as flavonoid, adrenaline, polysaccharide, various vitamins, amino acid and the like, is mainly used for resisting allergy, inflammation and inflammation, resisting various external irritation on the skin, clearing away heat and toxic materials, cooling blood and reducing swelling, can be externally used for treating sores, ulcers, carbuncles, furuncles, erysipelas, tinea, mosquito bites and the like, and has the function of removing acne. "Primary disease formula" cloud: all sores and itching sores belong to heart fire, purslane is pungent and cold and can cool blood and dissipate heat, so that symptoms, carbuncle sores, furuncles, white baldness and thirty-six kinds of wind-induced sores are mainly caused, swelling and treatment are caused by pounding for application, root-pulling is treated by swelling and dispersing, and malignant substances are all removed by juicing and taking, and the external and internal application are also required; recorded in Zhao Zhang Han nan clinical experience Collection, the purslane washing prescription has the effects of clearing heat and removing toxicity, and removing dampness and relieving itching, and is mainly used for treating acute eczema, allergic dermatitis, contact dermatitis (eczema), erysipelas and impetigo herpetifomis (impetigo).
Fructus forsythiae, its fruit can be used as medicine, contain effective cost such as forsythol, sterol compound, saponin (without hemolytic), flavonol glycoside and malpigenin, wherein saponin and flavonol glycoside can promote the formation of inflammatory barrier, reduce capillary permeability, reduce inflammatory exudation, eliminate local red swelling caused by acne, can keep normal skin, reduce the occurrence of acne and folliculitis.
The michelia alba contains substances such as aromatic volatile oil, antioxidant, bacteriocin and the like, has fragrant smell, and can relax stress, stabilize emotion and make people happy. The Michelia alba is used for caring skin, and has effects of keeping moisture and preventing allergy; balancing sebum secretion, preventing and treating acne, and is helpful for oil and dry skin; activating aged skin cells, promoting skin blood circulation, and whitening skin; has the function of recovering regeneration, and is suitable for massaging scar skin.
Chamomile, known as "miracle flower" from ancient times, contains volatile oil, choline, stachydrine, amino acids, flavonoids, vitamin B1, chrysanthemum lactone, chrysanthenone, chrysanthenol and other components in its extract, and has the functions of resisting oxidation, resisting blood vessel proliferation, diminishing inflammation, resisting allergy and resisting virus.
Borneol and levomenthol can improve the cooling and itching relieving effects. Wherein the levo-menthol has antipruritic, analgesic, antiseptic, irritant, anesthetic, refreshing and anti-inflammatory effects, and can be used for treating headache, neuralgia, pruritus, airway inflammation, atrophic rhinitis and hoarseness; borneol can be used for treating block pattern coma, conjunctival congestion with swelling and pain, sore throat, aphtha, sore and ulcer with swelling and pain, unhealing after ulceration, etc.
Phenoxyethanol is used as fixative, insect repellant, disinfectant and antiseptic.
The alcohol is used for dissolving Borneolum Syntheticum, levomenthol and phenoxyethanol, and has disinfectant and antibacterial effects.
The invention has the beneficial effects that: the invention is a pure herbal essence formula, natural herbal stock solution does not contain allergic and irritant components such as essence, camphor and the like, is mild and natural, has fragrant smell, quickly relieves discomfort caused by mosquito bites, relieves itching and protects the skin.
Detailed Description
The following provides a detailed description of embodiments of the invention.
Example 1
The herbal antipruritic lotion comprises the following raw materials in parts by weight: 15g of perilla extract, 15g of purslane extractive solution, 5g of forsythia extract, 5g of gardenia extract, 5g of chamomile extract, 10g of alcohol, 1g of borneol, 1g of levorotatory menthol and 0.2g of phenoxyethanol.
Example 2
The herbal antipruritic lotion comprises the following raw materials in parts by weight: 25g of perilla extract, 25g of purslane extractive solution, 15g of forsythia extract, 15g of gardenia extract, 15g of chamomile extract, 40g of alcohol, 4g of borneol, 5g of levorotatory menthol and 1.2g of phenoxyethanol.
Example 3
The herbal antipruritic lotion comprises the following raw materials in parts by weight: 21g of perilla extract, 21g of purslane extractive solution, 12g of forsythia extract, 12g of gardenia extract, 12g of chamomile extract, 25g of alcohol, 2.5g of borneol, 3g of levomenthol and 1g of phenoxyethanol.
Example 4
The herbal antipruritic lotion comprises the following raw materials in parts by weight: 18g of perilla extract, 18g of purslane extractive solution, 8g of forsythia extract, 8g of gardenia extract, 8g of chamomile extract, 28g of alcohol, 1g of borneol, 1g of levorotatory menthol and 0.5g of phenoxyethanol.
Example 5
The herbal antipruritic lotion comprises the following raw materials in parts by weight: 22g of perilla extract, 22g of purslane extractive solution, 12g of forsythia extract, 12g of gardenia extract, 12g of chamomile extractive solution, 32g of alcohol, 2g of borneol, 2g of levomenthol and 1g of phenoxyethanol.
Example 6
The herbal antipruritic lotion comprises the following raw materials in parts by weight: 20g of perilla extract, 20g of purslane extractive solution, 10g of forsythia extract, 10g of gardenia extract, 10g of chamomile extract, 30g of alcohol, 1.5g of borneol, 1.5g of levomenthol and 0.75g of phenoxyethanol.
Example 7
A preparation method of herbal antipruritic lotion comprises the following steps:
a. respectively taking 20g of perilla extract, 20g of purslane extractive, 10g of forsythia extract, 10g of gardenia extractive and 10g of chamomile extractive according to the weight, and uniformly stirring at room temperature to obtain synthetic liquid A;
b. taking 30g of alcohol according to the weight, adding a mixture of 0.75g of phenoxyethanol, 1.5g of levomenthol and 1.5g of borneol, and stirring again to dissolve uniformly to prepare synthetic liquid B;
c. and mixing the liquid A and the liquid B to obtain the herbal itching relieving lotion.
Example 8
A preparation method of herbal itching relieving paste comprises the following steps:
a. taking 20g of purple perilla, 20g of purslane, 20g of weeping forsythia, 10g of michelia alba and 10g of chamomile according to the weight, and adding 1000g of olive oil;
b. extracting for 50 minutes under the action of extraction equipment and ultrasonic waves, and taking 150g of solution;
c. heating the solution to 50 ℃, then dissolving 30g of beeswax, adding 1g of borneol, 1g of levo-menthol and 1.5g of phenoxyethanol, fully and uniformly dissolving, and naturally cooling to obtain the herbal itching relieving ointment.
In the experimental process, 60 patients are taken as experimental objects, wherein the experimental objects comprise 30 male patients, 30 female patients, 10 children aged 0-5 years, 10 children aged 6-11 years, 10 children aged 12-17 years, 10 young children aged 18-29 years, 10 middle aged 30-55 years and 10 old patients aged 56-80 years; the preparation method comprises the following steps of randomly dividing 60 patients into three groups, wherein each group comprises 10 men and women, and comprises a model group, a control group and a treatment group, wherein the model group members do not use any itching relieving products, the control group members use conventional itching relieving products (such as floral water, Manxifulon peppermint cream and the like), and the treatment group members use the herbal itching relieving lotion; the control group and the treatment group begin to use corresponding itching-relieving products to be smeared on mosquito bite parts once at the same time, and the average scratching times (shown in table 1), the skin swelling rate (shown in table 2) and the skin allergy condition (shown in table 3) of each group at each stage are recorded;
Figure BDA0001622463440000061
TABLE 1
Figure BDA0001622463440000062
TABLE 2
Figure BDA0001622463440000063
TABLE 3
The above data show that: the herbal itching relieving lotion has remarkable effects on relieving itching, resisting inflammation, reducing swelling and the like, is a pure herbal essence formula, is a natural herbal stock solution, does not contain allergic and stimulating components such as essence, camphor and the like, is mild and natural, has fragrant smell, has no irritation to skin, can quickly relieve discomfort caused by mosquito bites, relieves itching, protects skin and quickly reduces swelling; provides a better pharmacodynamic basis for treating pruritus caused by mosquito bites.
The above-mentioned embodiments only express the specific embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the present invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention.

Claims (1)

1. The herbal antipruritic lotion is characterized by comprising the following raw materials in parts by weight: 18-22 parts of perilla extract, 18-22 parts of purslane extract, 8-12 parts of forsythia extract, 8-12 parts of gardenia extract, 8-12 parts of chamomile extract, 28-32 parts of alcohol, 1-2 parts of borneol, 1-2 parts of levomenthol and 0.5-1 part of phenoxyethanol.
CN201810311446.4A 2018-04-09 2018-04-09 Herbal antipruritic lotion Expired - Fee Related CN108392445B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109044909A (en) * 2018-09-12 2018-12-21 广西古瑶方药妆研发科技有限公司 A kind of natural sponge gourd bleeding water whitening foster skin Essence
CN108852956A (en) * 2018-10-08 2018-11-23 广东云瑶生物医药科技有限公司 Borneol facial mask liquid and preparation method thereof
CN111110758B (en) * 2018-10-31 2021-12-07 西南民族大学 Ointment and application thereof
CN112472757A (en) * 2020-12-21 2021-03-12 韩兵 Bee venom spray disinfectant and preparation method thereof
CN114617140A (en) * 2022-03-19 2022-06-14 陇东学院 Traditional Chinese medicine compound thyme cream capable of repelling mosquitoes, diminishing inflammation and relieving itching and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101293076A (en) * 2007-04-28 2008-10-29 肖旭 Pruritic and detumescence externally used liquid medicine of hyacinth orinntal composition
CN104958516A (en) * 2015-06-03 2015-10-07 刘强 Detumescence and itching relieving liquid
CN106511183A (en) * 2016-12-24 2017-03-22 江西宜信堂医疗科技有限公司 Mosquito-repelling toilet water and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101293076A (en) * 2007-04-28 2008-10-29 肖旭 Pruritic and detumescence externally used liquid medicine of hyacinth orinntal composition
CN104958516A (en) * 2015-06-03 2015-10-07 刘强 Detumescence and itching relieving liquid
CN106511183A (en) * 2016-12-24 2017-03-22 江西宜信堂医疗科技有限公司 Mosquito-repelling toilet water and preparation method thereof

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