CN104382009A - Health care tablets using VC and curcumin as components of main drugs - Google Patents
Health care tablets using VC and curcumin as components of main drugs Download PDFInfo
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- 235000012754 curcumin Nutrition 0.000 title claims abstract description 80
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
Abstract
The present invention belongs to the technical filed of health care products, and discloses compositions of health care tablets with certain efficacy using VC and curcumin as components of main drugs and a preparation method thereof. The components of main drugs include Turmeric rhizome powder 10-80%, curcumin 5-75% and VC 5-20%. Pharmaceutical acceptable auxiliary materials and excipients are added into the components of main drugs and then the mixture is pressed into tablets. The health care tablets have features of easily available raw materials, low production cost, non-toxic side effects, safety eating, convenient storage, carryover and use.
Description
Technical field
The invention belongs to field of health care products, be specifically related to a kind of with vitamin C and curcumin be the health care tablet of main ingredient composition constituent and preparation method.
Background technology
Turmeric is that Zingiber ginger belongs to herbaceos perennial, is the plant of integration of drinking and medicinal herbs, is also the food additives at home and abroad all allowing to use simultaneously.Containing a large amount of curcumins in the rhizome of turmeric, it is the strongest natural antibacterial agent.The death of tumour cell can be promoted, stop the generation of angiocardiopathy, development.
Our said curcumin, typically refer to the mixture of curcumin, Demethoxycurcumin, Bisdemethoxycurcumin, curcumin is wherein most important active component.Curcumin has anti-breast cancer and prostate cancer, prevention senile dementia, and reducing blood lipid, promoting blood circulation and removing obstruction in channels, anti-oxidant, anti-inflammatory and cholagogic such as to protect the liver at physiology and the pharmacological action.
Modern medicine thinks that the curcumin composition in turmeric is slightly acid phenolic substance, has and promotes that macrophage is formed, thus improve the function of immunity of organisms.This immunocyte can remove amyloplaste (a kind of energy forms the brain plaque material be associated with senile dementia), thus reaches effect of prevention and therapy senile dementia.Now prove that curcumin has good effect to the generation and development that prevent breast cancer and prostate cancer; Simultaneously curcumin also have that cholagogic protects the liver, reducing blood lipid, promoting blood circulation and removing obstruction in channels, anti-oxidant, antiatherosclerosis and the physiology such as anti-inflammatory, anti AIDS virus, pharmacological action.
Chinese always have the custom utilizing food to carry out self health care, are commonly called as " dietotherapy ".During spring and autumn, Confucius just advocates: " often eat and do not remove ginger." meaning: people should eat ginger every day throughout the year.It is said that Confucius just has and chew several pieces custom of ginger every day after meal.Among the people have saying of " three ginger, being better than and drinking ginseng soup morning " and " ginger glabrousleaf asiabell root in October "." winter eats the radish summer and eats ginger, and doctor Lao does not write out a prescription to also have " every day three ginger, not labor doctor prescribed prescription "." proverb such as " often eat ginger, be not afraid of hardships ".Ginger in life, except being used as flavor enhancement, pot foods, also demonstrates local flavor and the glamour of its uniqueness in beauty treatment, health care.Ginger is hot in nature, and taste is pungent.Return spleen, stomach, the heart, lung channel.Effect: Wen Zhong, Hui Yang, warming lung to reduce watery phlegm.There are loose cold sweating, preventing phlegm from forming and stopping coughing and the multiple efficacies such as stomach, preventing or arresting vomiting.It is dry that rhizome has promoting qi circulation and relieving pain, dysmenorrhoea breaks blood, effects such as Liao Paralysis of dispeling the wind.Rhizoma zingiberis head enters taste, hotly by taste cold-evil, can help the yang-energy of taste with it.Commonly use and control taste sympotoms caused by cold factors, disease sees epigastric pain, vomiting is had loose bowels.In every case taste sympotoms caused by cold factors, be no matter invade in exogeneous cold or YANG QI deficiency all applicable.Therefore, develop a kind of health care tablet based on curcumin, necessarily have market widely, be bound to be subject to acceptance and the accreditation of consumers in general.
" flu " is always divided into " anemopyretic cold " and " anemofrigid cold " by the traditional Chinese medical science, and anemopyretic cold belongs to Yangming Channel disease, caused by evil criminal's table of wind-heat, lung qi are become estranged.Be more common in hot season in summer, treatment adopts wind-dispelling heat-dissipating more.Mostly anemofrigid cold is because of affection by exopathogenic cold-wind, and namely wind is suffered from cold and the flu that causes, and the autumn and winter occur more.Its symptom is that aversion to cold weighs, aches all over, runny nose of having a stuffy nose, bring up phlegm when one coughs.The white the tip of the tongue of tongue is not red, floating and tense pulse or floating slow.Anemofrigid cold treatment on based on sweating.Adopt among the people drinks ginger decoction or other easily make the soup class of people's sweating more, and namely sweating recovers.Active ingredient in turmeric is curcumin, has the effect of inducing sweat and dispelling exogenous evils, has certain therapeutic action to anemofrigid cold.In anemofrigid cold autumn and winter occurred frequently and spring, often take the effect can played preventing cold and improve immunity.
Vitamin C is water miscible antioxidant, has important Physiology and biochemistry effect to body itself.Such as: the biosynthesis 1. promoting ossein, be beneficial to the healing of tissue injury, promote the synthesis of collagen, prevent bleeding gums; Promote the growth of tooth and bone, prevent joint and pain in waist and lower extremities.2. promote the metabolism of tyrosine and tryptophan in amino acid, extend the human body life-span, strengthen the human body anti-stress ability of environment and immunity to external world.3. the utilization of iron, calcium and folic acid is improved.Improve the metabolism of fat and lipoid particularly cholesterol, prevent cardiovascular disease.4. prevention of arterial sclerosis.The excretion of cholesterol can be promoted, prevent cholesterol from depositing at Wall of Artery, the atheromatous plaque of deposition even can be made to dissolve.5. antioxidant action.Other antioxidant can be protected, as VitAVitE, unrighted acid etc., prevent the injury of radical pair human body.In addition, vitamin C also has certain face-nursing function, suppresses the increase of pigment, make freckle thin out, have whitening, reduces the effect of pore and adjustment dermatoglyph.
The effect of curcumin is wide, good effect.Be typical functional dietotherapy product, but there is certain seasonality due to the product ginger of China, store difficulty comparatively large, and edible process is too complicated, is not easy to long-term, regular and takes at any time, therefore, have impact on its marketability.
At present, mostly the turmeric powder that can buy of market and the health product containing curcumin are imported product.Product category is enriched, and have curcumin capsule, tablet, tea and drinks, primary efficacy is hepatoprotective effect.But because the solubization of turmeric powder and curcumin is poor, and the features such as easy decomposition, greatly hinder the application of curcumin in functional food and health products.The market prospects developing this series health-care products with independent intellectual property right and nutriment are fine.
China enters aging society, health care, improves quality of life and more and more becomes the requirement of people to health products and functional food.The incidence of disease of senile dementia increases in China fast with the speed of annual 14%, curcumin be generally acknowledge at present to the effective native compound of prevention and therapy senile dementia.Therefore, the release of such health products and functional food is bound to be subject to the welcome in market.
Summary of the invention
Primary and foremost purpose of the present invention is to provide a kind of based on vitamin C and curcumin, has the tablet of certain health-care efficacy.Add VC in this tablet, not only can stop the oxidation Decomposition of curcumin active ingredient, make that its original cholagogic protects the liver, reducing blood lipid, increase immunity, skin maintenance, anti-breast cancer and the effect such as prostate cancer, antifatigue be guaranteed.Meanwhile, the synergy of curcumin and VC, to prevention and the generation and the development that stop senile dementia, and all has well treatment and preventive effect to anemofrigid cold.This tablet has raw material and is easy to get, and low production cost, has no side effect, edible safety, is convenient to store, the feature such as carry and take, can long-term taking and obvious health-care efficacy.
The object of the present invention is to provide above-mentioned a kind of with VC and curcumin be the health care tablet of main ingredient composition constituent and preparation method.
Object of the present invention is achieved through the following technical solutions:
A kind of health care tablet being main ingredient composition with VC and curcumin is by following constituent and preparation method:
Main ingredient raw materials by weight is turmeric rhizome powder: 10-80%, curcumin: 5-75%, VC:5-20%, add pharmaceutical adjunct compressing tablet and get final product.
Curcumin rhizome powder of the present invention, comes from the stem of turmeric plant, root.Curcumin is for buy from market.
Tablet provided by the invention, comprising VC, curcumin or turmeric rhizome powder.
Tablet provided by the invention, wherein also comprises the acceptable auxiliary material of pharmacy and excipient.
Tablet provided by the invention, comprising appropriate VC, turmeric rhizome powder or curcumin.
Tablet provided by the invention, wherein active component is made up of turmeric rhizome powder, curcumin and VC, and the weight proportion of three is: turmeric rhizome powder: 10-80%, curcumin: 5-75%, VC:5-20%.Supplementary element has filler, flavor enhancement, excipient, salty sweet conditioning agent, pH value equilibrium modifier and disintegrant, above composition compressing tablet and get final product.
In turmeric rhizome powder and curcumin, add VC, be the synergy in view of curcumin and VC and BA.First, VC is water miscible antioxidant, and its interpolation can protect curcumin effectively, suppresses the oxidation Sum decomposition of curcumin.Secondly, effect such as anti-stress ability and immunity of the enhancing human body that VC has environment to external world, it is the conventional adding ingredient in current nearly all compound cold drug, the use in conjunction of curcumin and VC in the present invention, the original inducing sweat and dispelling exogenous evils function of curcumin is further strengthened, makes it have prevention and therapy meaning to anemofrigid cold.
the present invention has the following advantages and effect relative to prior art tool:
The health care tablet that is main ingredient composition with VC and curcumin of the present invention, in sheet, content (every hectogram) the comparatively fresh turmeric of curcumin is high by 82%; Comparatively rhizoma zingiberis is yellow high by 68%.Turmeric is originally relieved the effect of alcohol, protects the liver, antifatigue, develop immunitypty, reducing blood lipid function promoted, ensure its health-care efficacy.
The health care tablet that is main ingredient composition with VC and curcumin of the present invention, the use in conjunction of curcumin and VC, can protect curcumin effectively, suppresses the oxidation Sum decomposition of curcumin.Adding the curcumin of VC, more not add the curcumin content of Vc high by 38%.Illustrate that VC effectively prevents the oxidation Sum decomposition of curcumin.
The health care tablet that is main ingredient composition with VC and curcumin of the present invention, the use in conjunction of VC and curcumin, makes curcumin effect in loose cold sweating, preventing phlegm from forming and stopping coughing be effectively improved; Make the patient of anemofrigid cold, especially when first sense chill, coordinate the patient taking this tablet, the course of disease shortens 36.6%, and greatly alleviates " flu " symptom of patient.
The health care tablet that is main ingredient composition with VC and curcumin of the present invention, add disintegrant, make curcumin more easily water-soluble, thus, can improve curcumin content in tablets, in this tablet, the content of curcumin improves 56% compared with the content of curcumin granule.
The health care tablet that is main ingredient composition with VC and curcumin of the present invention, curcumin can by tongue, pharyngeally carry out first time and absorb, the infiltration rate of this tablet curcumin comparatively curcumin capsule improves 33%, the absorption Quality advance 38% of curcumin.
The health care tablet that is main ingredient composition with VC and curcumin of the present invention, the use in conjunction of curcumin and VC, not only stops the oxidation Decomposition of the active ingredient of curcumin.Make that the original cholagogic of curcumin protects the liver, reducing blood lipid, increase immunity, skin maintenance, anti-breast cancer and the effect such as prostate cancer, antifatigue be guaranteed.Meanwhile, to prevention and stop the generation of senile dementia and development function remarkable; To anemofrigid cold, there is good adjuvant treatment effect.This tablet has raw material and is easy to get, and low production cost, has no side effect, edible safety, can the feature such as long-term taking and obvious health-care efficacy.
Detailed description of the invention
Be described in further detail the present invention below in conjunction with embodiment, but embodiments of the present invention are not limited only to this, embodiment does not limit in any form the present invention.
Embodiment 1
A kind of with VC and curcumin be the health care tablet of main ingredient composition constituent and preparation method:
Active component is according to turmeric rhizome powder in percentage by weight (0.5g/ sheet): 80%; Curcumin: 5%; Vitamin C: 15%; Add pharmaceutical adjunct compressing tablet and get final product.
Embodiment 2
With the health care tablet that VC and curcumin are main ingredient composition, active component is according to turmeric rhizome powder in percentage by weight (0.5g/ sheet): 10%; Curcumin: 75%; Vitamin C: 15%; Add pharmaceutical adjunct compressing tablet and get final product.
Embodiment 3
With the health care tablet that VC and curcumin are main ingredient composition, active component is according to turmeric rhizome powder in percentage by weight (0.5g/ sheet): 40%; Curcumin: 40%; Vitamin C: 20%; Add pharmaceutical adjunct compressing tablet and get final product.
Embodiment 4
With the health care tablet that VC and curcumin are main ingredient composition, active component is according to turmeric rhizome powder in percentage by weight (0.5g/ sheet): 35%; Curcumin: 55%; Vitamin C: 10%; Add pharmaceutical adjunct compressing tablet and get final product.
Embodiment 5
With the health-care agent sheet that VC and curcumin are main ingredient composition, active component is according to turmeric rhizome powder in percentage by weight (0.5g/ sheet): 65%; Curcumin: 30%; Vitamin C: 5%; Add pharmaceutical adjunct compressing tablet and get final product.
Embodiment 6
Tablet obtained by embodiment 1-5, carry out Double-blind randomized clinical trial by the patient of anemofrigid cold, experimental program is:
(1) only conventional therapy is carried out;
(2) on the basis of (1), the tablet taken obtained by embodiment 1 is increased, every day 2 times, each 2;
(3) on the basis of (1), the tablet taken obtained by embodiment 2 is increased, every day 2 times, each 2;
(4) on the basis of (1), the tablet taken obtained by embodiment 3 is increased, every day 2 times, each 2;
(5) on the basis of (1), the tablet taken obtained by embodiment 4 is increased, every day 2 times, each 2;
(6) on the basis of (1), the tablet taken obtained by embodiment 5 is increased, every day 2 times, each 2;
Result of the test shows, scheme 2 shortens 37.5% compared with the course of disease of scheme 1; Scheme 3 shortens 37.3% compared with the course of disease of scheme 1; Scheme 4 comparatively scheme 1 shortens 38.1%; Scheme 5 shortens 37.9% compared with the course of disease of scheme 1; Scheme 6 shortens 36.9% compared with the course of disease of scheme 1; The above results illustrates, the tablet obtained by embodiment 1-5, efficient close in supplemental treatment anemofrigid cold process, curative effect is substantially identical.
Tablet obtained by embodiment 1-5, carry out Double-blind randomized clinical trial by the patient of anemofrigid cold, testing program is:
(1) only conventional therapy is carried out;
(2) on the basis of (1), the tablet taken obtained by embodiment 1-5 is increased, every day 2 times, each 2;
(3) on the basis of (1), increase and take VC, (use amount is equal with VC in (2));
(4) on the basis of (1), increase and take curcumin; (use amount is equal with curcumin in (2));
Result of the test is: the result for the treatment of of scheme 2 is best, and scheme 2 shortens 36.6% compared with the course of disease of scheme 1, and patients symptomatic significantly alleviates.Scheme 2 shortens 26.3% compared with the course of disease of scheme 3, and patients symptomatic alleviates to some extent.Scheme 2 shortens 17.3% compared with the course of disease of scheme 4, and patients symptomatic has and necessarily alleviates.Above-mentioned result of the test shows, tablet in treatment Be very effective of the present invention improves.
Above-described embodiment is the better matched combined of each composition of the present invention; but embodiment of the present invention are not restricted to the described embodiments; the amendment made under other any does not deviate from Spirit Essence of the present invention and principle, substitute, combine, simplify and all should be considered as equivalent replacement mode, be included within protection scope of the present invention.
Claims (2)
1., with a composition tablet for vitamin C, curcumin and turmeric rhizome powder, it is characterized in that its active component mass percent is turmeric rhizome powder: 10-80%, curcumin: 5-75%, VC:5-20%, add pharmaceutical adjunct compressing tablet and get final product.
2. tablet according to claim 1, is characterized in that the specification of described tablet is 0.5g/ sheet, and namely wherein the content sum of main ingredient active component vitamin C, turmeric rhizome powder, curcumin is 0.5g/ sheet.
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| CN201410574535.XA CN104382009A (en) | 2014-10-24 | 2014-10-24 | Health care tablets using VC and curcumin as components of main drugs |
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| CN201410574535.XA CN104382009A (en) | 2014-10-24 | 2014-10-24 | Health care tablets using VC and curcumin as components of main drugs |
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Application publication date: 20150304 |