CN104380112B - 妊娠期糖尿病的母体生物标志物 - Google Patents
妊娠期糖尿病的母体生物标志物 Download PDFInfo
- Publication number
- CN104380112B CN104380112B CN201380031224.2A CN201380031224A CN104380112B CN 104380112 B CN104380112 B CN 104380112B CN 201380031224 A CN201380031224 A CN 201380031224A CN 104380112 B CN104380112 B CN 104380112B
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- fibronectin
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/471—Pregnancy proteins, e.g. placenta proteins, alpha-feto-protein, pregnancy specific beta glycoprotein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261623690P | 2012-04-13 | 2012-04-13 | |
| US61/623,690 | 2012-04-13 | ||
| PCT/US2013/030152 WO2013154709A1 (en) | 2012-04-13 | 2013-03-11 | Maternal biomarkers for gestational diabetes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104380112A CN104380112A (zh) | 2015-02-25 |
| CN104380112B true CN104380112B (zh) | 2017-05-24 |
Family
ID=49325612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380031224.2A Active CN104380112B (zh) | 2012-04-13 | 2013-03-11 | 妊娠期糖尿病的母体生物标志物 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US8852873B2 (enExample) |
| EP (1) | EP2836845B1 (enExample) |
| CN (1) | CN104380112B (enExample) |
| ES (1) | ES2684976T3 (enExample) |
| IN (1) | IN2014DN09410A (enExample) |
| WO (1) | WO2013154709A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160025737A1 (en) * | 2014-07-25 | 2016-01-28 | Diabetomics, Llc | Biomarkers for assessment of preeclampsia |
| EP3271730B1 (en) * | 2015-03-20 | 2019-10-09 | IQ Products B.V. | Novel marker for gestational diabetes |
| CN106706928A (zh) * | 2017-01-19 | 2017-05-24 | 深圳大学 | 一种妊娠期糖尿病的早期预测标志物及其检测方法 |
| CN107024590A (zh) * | 2017-03-13 | 2017-08-08 | 新疆医科大学 | 一种诊断1型和2型糖尿病的血清蛋白标志物组 |
| CN113495150A (zh) * | 2020-03-19 | 2021-10-12 | 首都医科大学附属北京世纪坛医院 | 尿液白蛋白及其多肽片段在妊娠糖尿病中的应用 |
| CN113514634A (zh) * | 2020-04-09 | 2021-10-19 | 武汉市朗典精医生物科技有限公司 | 制备检测Adipo/SHBG双指标免疫层析试剂盒 |
| CN113804879A (zh) * | 2020-06-15 | 2021-12-17 | 北京康美天鸿生物科技有限公司 | 幽门螺旋杆菌IgM和IgG抗体联合检测试剂盒 |
| EP4428535A1 (en) * | 2023-03-09 | 2024-09-11 | Servizo Galego de Saude | Diagnosis, monitoring or prognosis of diabetes or prediabetes |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4855242A (en) | 1986-04-14 | 1989-08-08 | Joslin Diabetes Center, Inc. | Method of detecting antibodies |
| DE3800048A1 (de) | 1987-05-14 | 1988-11-24 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung eines antikoerpers in menschlichen koerperfluessigkeiten |
| US5645998A (en) | 1988-12-13 | 1997-07-08 | University Of Florida Research Foundation | Methods and compositions for the early detection and treatment of insulin dependent diabetes mellitus |
| US5175085A (en) | 1990-02-20 | 1992-12-29 | Board Of Regents, The University Of Texas System | Methods and compositions for diagnosing autoimmune insulin dependent diabetes mellitus |
| JP2727377B2 (ja) | 1990-09-07 | 1998-03-11 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 糖尿病自己抗体の検出方法 |
| US5512447A (en) | 1990-09-07 | 1996-04-30 | The Regents Of The University Of California | Methods for the diagnosis and treatment of diabetes |
| US5674978A (en) | 1990-09-21 | 1997-10-07 | The Regents Of The University Of California | Peptides derived from glutamic acid decarboxylase |
| DE4129849A1 (de) | 1991-02-14 | 1992-08-27 | Boehringer Mannheim Gmbh | Monoklonale antikoerper gegen humane pankreas-inselzellen |
| IL101872A0 (en) | 1991-05-15 | 1992-12-30 | Univ Washington | Cloning and expression of human islet glutamic acid decarboxylase autoantigen |
| US5674692A (en) | 1991-09-06 | 1997-10-07 | Baekkeskov; Steinunn | Methods for diabetes susceptibility assessment in asymptomatic patients |
| US5200318A (en) | 1992-05-13 | 1993-04-06 | Miles Inc. | Diagnosis of IDDM with a panel of immunoreagents |
| US5691448A (en) | 1992-12-03 | 1997-11-25 | Baekkeskov; Steinunn | Reagents and methods for the diagnosis and treatment of diabetes and stiff man syndrome |
| IL108587A (en) | 1993-02-09 | 1998-01-04 | Univ Monash | Methods and kit for diagnosing diabetes and pre-diabetic conditions |
| ATE221200T1 (de) | 1993-04-16 | 2002-08-15 | Univ California | Verfahren zur bestimmung der diabetesanfälligkeit bei asymptomatischen patienten |
| US5547847A (en) | 1993-09-07 | 1996-08-20 | University Of Washington | Diagnosis of insulin-dependent diabetes |
| US5561049A (en) | 1994-09-21 | 1996-10-01 | Behringwerke Ag | Method for detecting antibodies |
| US6391651B1 (en) | 1995-08-11 | 2002-05-21 | The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services | Materials and methods for detection of insulin dependent diabetes |
| US5989551A (en) | 1995-10-25 | 1999-11-23 | The United States Of America As Represented By The Department Of Health And Human Services | Materials and methods for detection and treatment of insulin-dependent diabetes |
| US5821334A (en) | 1996-01-26 | 1998-10-13 | Vanderbilt University | Insulin-dependent diabetes mellitus-specific chimeric polypeptides |
| AU1989097A (en) | 1996-03-06 | 1997-09-22 | University Of Washington | Diabetes mellitus 37 kd autoantigen protein-tyrosine phosphatase |
| US5670377A (en) * | 1996-03-14 | 1997-09-23 | Sansum Medical Research Foundation | Method of diagnosing gestational diabetes |
| AUPO468597A0 (en) | 1997-01-21 | 1997-02-13 | Montech Medical Developments Pty Ltd | Expression in yeast of antigenically active, recombinant hybrid glutamic acid decarboxylase |
| US6303325B1 (en) | 1998-05-29 | 2001-10-16 | Dade Behring Inc. | Method for detecting analytes |
| DE19839736A1 (de) | 1998-09-01 | 2000-03-02 | Roche Diagnostics Gmbh | Humane monoklonale Antikörper gegen Inselzellantigen IA-2 |
| EP1340077B1 (en) | 2000-10-17 | 2006-01-25 | Besst-Test ApS | Assay for directly detecting an inflammatory indicator in a body fluid sample |
| AU2002256168B2 (en) | 2001-04-10 | 2007-09-20 | The Board Of Trustees Of The Leland Stanford Junior University | Therapeutic and diagnostic uses of antibody specificity profiles |
| US20050130245A1 (en) | 2001-09-17 | 2005-06-16 | Syn X Pharma, Inc. | Diagnosis and treatment of early pre-type-1 diabetes utilizing neuronal proteins |
| AU2003237312A1 (en) | 2002-05-29 | 2003-12-19 | University Of Washington | Mutants of gad65 and ian5 relating to diabetes |
| FR2847263B1 (fr) | 2002-11-18 | 2006-01-13 | Commissariat Energie Atomique | Polynucleotide specifique de la cellule pancreatique beta des ilots de langerhans |
| US9557325B2 (en) | 2003-06-09 | 2017-01-31 | Redox-Reactive Reagents Llc | Method of altering the binding specificity of proteins by oxidation-reduction reactions |
| ATE518886T1 (de) | 2003-06-09 | 2011-08-15 | Redox Reactive Reagents L L C | Verfahren zur änderung der bindungsspezifität von plasmaproteinen durch oxidations- reduktionsreaktionen |
| CA2529759A1 (en) | 2003-06-20 | 2005-10-13 | University Of Florida | Biomarkers for differentiating between type 2 and type 2 diabetes |
| TW200508609A (en) | 2003-07-15 | 2005-03-01 | Bioarray Solutions Ltd | Detection of cell membrane-associated proteins using membrane fragments displayed on encoded microparticle arrays |
| US7323346B2 (en) * | 2003-08-14 | 2008-01-29 | The General Hospital Corporation | Screening for gestational disorders |
| SE0400683D0 (sv) * | 2004-03-19 | 2004-03-19 | Forskarpatent I Syd Ab | Use of modified extracellular matrix proteins in diagnosis and treatment of a atherosclerosis |
| CA2575675A1 (en) * | 2004-07-30 | 2006-03-09 | Adeza Biomedical Corporation | Oncofetal fibronectin as a marker for disease and other conditions and methods for detection of oncofetal fibronectin |
| ITRM20050398A1 (it) | 2005-07-26 | 2007-01-27 | Gian Franco Bottazzo | Metodo per la rilevazione di cellule t in pazienti neodiagnosticati per diabete di tipo 1. |
| US8691944B2 (en) * | 2005-10-04 | 2014-04-08 | The Research Foundation For The State University Of New York | Fibronectin polypeptides and methods of use |
| WO2007062789A1 (en) * | 2005-11-29 | 2007-06-07 | F. Hoffmann-La Roche Ag | Fibronectin as target/marker for insulin resistance |
| CN101416063A (zh) | 2006-02-06 | 2009-04-22 | 拉帕波特家族医学科学研究所 | 用于诊断t1dm的方法和试剂盒 |
| US20070224638A1 (en) | 2006-03-27 | 2007-09-27 | Institut Pasteur | Secreted proteins as early markers and drug targets for autoimmunity, tumorigenesis and infections |
| US9023984B2 (en) | 2006-12-29 | 2015-05-05 | The Regents Of The University Of Colorado, A Body Corporate | Diagnostic and therapeutic target for autoimmune diseases and uses thereof |
| DK2121905T3 (en) | 2007-02-21 | 2016-05-17 | Univercell Biosolutions | HUMAN pancreatic beta-CELL LINES FOR DIAGNOSIS OF DIABETES |
| EP2198304B1 (en) | 2007-09-06 | 2016-01-13 | University of Washington | Molecules and methods for treatment and detection of diabetes |
| WO2009045403A2 (en) * | 2007-10-01 | 2009-04-09 | The Board Of Trustees Of The Leland Stanford Junior University | MENIN REGULATION OF β-ISLET CELL PROLIFERATION |
| WO2009097584A1 (en) * | 2008-01-30 | 2009-08-06 | Proteogenix, Inc. | Maternal serum biomarkers for detection of pre-eclampsia |
| WO2009097579A1 (en) * | 2008-01-30 | 2009-08-06 | Proteogenix, Inc. | Gestational age dependent proteomic changes of human maternal serum for monitoring maternal and fetal health |
| WO2009099603A1 (en) * | 2008-02-04 | 2009-08-13 | Women & Infants Hospital | Serum-based, diagnostic, biological assay to predict pregnancy disorders |
| US8722343B2 (en) | 2008-11-21 | 2014-05-13 | Carla Perego | Methods and compositions for the diagnosis and treatment of diabetes |
| KR101067815B1 (ko) | 2009-02-05 | 2011-09-27 | 서울대학교산학협력단 | 제1형 당뇨병의 신규한 진단 마커 |
| WO2011085057A2 (en) | 2010-01-06 | 2011-07-14 | The Regents Of The University Of Colorado, A Body Corporate | Methods for detecting insulin autoantibody |
| WO2013025759A1 (en) | 2011-08-16 | 2013-02-21 | Battelle Memorial Institute | Peptide and protein biomarkers for type 1 diabetes mellitus |
-
2013
- 2013-03-11 ES ES13775210.1T patent/ES2684976T3/es active Active
- 2013-03-11 CN CN201380031224.2A patent/CN104380112B/zh active Active
- 2013-03-11 WO PCT/US2013/030152 patent/WO2013154709A1/en not_active Ceased
- 2013-03-11 IN IN9410DEN2014 patent/IN2014DN09410A/en unknown
- 2013-03-11 EP EP13775210.1A patent/EP2836845B1/en active Active
- 2013-03-11 US US13/792,844 patent/US8852873B2/en active Active
- 2013-11-21 US US14/085,974 patent/US8975034B2/en active Active
-
2014
- 2014-10-16 US US14/516,383 patent/US9383370B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9383370B2 (en) | 2016-07-05 |
| EP2836845A1 (en) | 2015-02-18 |
| CN104380112A (zh) | 2015-02-25 |
| EP2836845A4 (en) | 2015-11-18 |
| US20140080157A1 (en) | 2014-03-20 |
| ES2684976T3 (es) | 2018-10-05 |
| US20130274123A1 (en) | 2013-10-17 |
| WO2013154709A1 (en) | 2013-10-17 |
| EP2836845B1 (en) | 2018-05-09 |
| US8852873B2 (en) | 2014-10-07 |
| IN2014DN09410A (enExample) | 2015-07-17 |
| US8975034B2 (en) | 2015-03-10 |
| US20150037822A1 (en) | 2015-02-05 |
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