CN104370830B - 一种5-三氟甲基尿嘧啶的合成方法 - Google Patents
一种5-三氟甲基尿嘧啶的合成方法 Download PDFInfo
- Publication number
- CN104370830B CN104370830B CN201410563415.XA CN201410563415A CN104370830B CN 104370830 B CN104370830 B CN 104370830B CN 201410563415 A CN201410563415 A CN 201410563415A CN 104370830 B CN104370830 B CN 104370830B
- Authority
- CN
- China
- Prior art keywords
- uracil
- solution
- trifluoromethyl
- sodium
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
Abstract
Description
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410563415.XA CN104370830B (zh) | 2014-10-21 | 2014-10-21 | 一种5-三氟甲基尿嘧啶的合成方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410563415.XA CN104370830B (zh) | 2014-10-21 | 2014-10-21 | 一种5-三氟甲基尿嘧啶的合成方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104370830A CN104370830A (zh) | 2015-02-25 |
CN104370830B true CN104370830B (zh) | 2016-07-13 |
Family
ID=52550066
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201410563415.XA Active CN104370830B (zh) | 2014-10-21 | 2014-10-21 | 一种5-三氟甲基尿嘧啶的合成方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN104370830B (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108383778B (zh) * | 2018-04-14 | 2019-12-24 | 青岛农业大学 | 一种含氟吡啶酮类化合物的合成方法 |
CN108218793B (zh) * | 2018-04-14 | 2019-10-11 | 青岛农业大学 | 一种含氟嘧啶酮类化合物的合成方法 |
CN114395770B (zh) * | 2022-01-25 | 2023-09-22 | 上海电力大学 | 一种电化学合成5-三氟甲基尿嘧啶化合物的方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103880760A (zh) * | 2014-04-18 | 2014-06-25 | 南京安源生物医药科技有限公司 | 一种5-三氟甲基尿嘧啶的合成方法 |
-
2014
- 2014-10-21 CN CN201410563415.XA patent/CN104370830B/zh active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103880760A (zh) * | 2014-04-18 | 2014-06-25 | 南京安源生物医药科技有限公司 | 一种5-三氟甲基尿嘧啶的合成方法 |
Also Published As
Publication number | Publication date |
---|---|
CN104370830A (zh) | 2015-02-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN104370830B (zh) | 一种5-三氟甲基尿嘧啶的合成方法 | |
CN104529794B (zh) | 啶酰菌胺中间体2-(4-氯苯基)苯胺的制备方法 | |
CN106188116A (zh) | 一种合成吡唑‑4‑硼酸频那醇酯的方法 | |
CN109096354A (zh) | 一种睾酮中间体母液回收利用方法 | |
US20180334421A1 (en) | Synthesis Method of 3,4-hexanedione | |
CN106928152A (zh) | 一种尿嘧啶的制备方法 | |
CN104817551A (zh) | 一种制备维生素b1盐酸盐的新方法 | |
CN107935870A (zh) | 一种2‑甲氨基‑5‑氯二苯甲酮的合成方法 | |
CN106748798A (zh) | 一种2,4-二硝基苯甲醚的合成方法 | |
CN105646334A (zh) | 一种2,6-吡啶二甲醇的制备方法 | |
CN108047299A (zh) | 坎利酮重要中间体的制备方法 | |
CN108329276A (zh) | 杂环衍生物及其制备和用途 | |
CN106883186A (zh) | 一种4,6‑二羟基嘧啶的制备方法 | |
CN105777595B (zh) | 一种适合工业化生产的福多司坦制备方法 | |
CN105968035A (zh) | 一种福多司坦的制备方法 | |
CN104230692A (zh) | 3,3-二甲基-1,2-环丙烷二羧酸的制备方法 | |
CN109438345A (zh) | 一种二氘代伯氨喹的合成方法 | |
CN104003936A (zh) | 一种氢溴酸右美沙芬的精制纯化方法 | |
CN103382171A (zh) | 福多斯坦氧化杂质的制备方法 | |
CN104370807B (zh) | 一种6-羟基-5-硝基烟酸的合成方法及其分离提纯方法 | |
CN104387264A (zh) | 一种合成2-氟-5-溴对苯二甲酸的方法 | |
CN103086818A (zh) | 由2-羟基丙二氰合成a-羟基酰胺的方法 | |
CN103304405B (zh) | 一种选择性氯化的方法 | |
CN106045997A (zh) | 2‑羟基‑1,5‑萘啶的制备方法 | |
CN108117490B (zh) | 一种对硝基苄醇的制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20180608 Address after: 226100 100 Dongting Lake Road, Linjiang Town, Haimen, Nantong, Jiangsu Patentee after: HAIMEN HAIKANG BIOMEDICAL TECHNOLOGY CO., LTD. Address before: 201321 205, 2 floor, 26 Lane 3399 lane, Kang Xin Road, Pudong New Area, Shanghai. Patentee before: SHANGHAI YAXING BIOLOGICAL PHARMACEUTICAL TECHNOLOGY CO., LTD. |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20210616 Address after: Room 303, No.5, Lane 1111, Miaojing Road, Pudong New Area, Shanghai Patentee after: SHANGHAI YAXING BIOMEDICAL TECHNOLOGY Co.,Ltd. Address before: 226100 100 Dongting Lake Road, Linjiang Town, Haimen, Nantong, Jiangsu Patentee before: HAIMEN HAIKANG BIOMEDICAL TECHNOLOGY Co.,Ltd. |