CN104367539A - Conditioning lotion containing cordyceps militaris ingredients and preparation method thereof - Google Patents

Conditioning lotion containing cordyceps militaris ingredients and preparation method thereof Download PDF

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Publication number
CN104367539A
CN104367539A CN201410684506.9A CN201410684506A CN104367539A CN 104367539 A CN104367539 A CN 104367539A CN 201410684506 A CN201410684506 A CN 201410684506A CN 104367539 A CN104367539 A CN 104367539A
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extract
aloe
radix
component
fermented product
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杨伟超
佟庆辉
王楠
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SHENYANG YUANKANG MEDICAL DEVICES Co Ltd
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SHENYANG YUANKANG MEDICAL DEVICES Co Ltd
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Abstract

The invention provides a conditioning lotion containing cordyceps militaris ingredients. The conditioning lotion contains the following 21 active ingredients: fermented aloes, a cordyceps extract, hydrolyzed royal jellies, a purslane extract, a persimmon leaf extract, an orange peel extract, a scutellaria baicalensis root extract, a phellinus linteus extract, a white willow bark extract, a vanilla extract, a Lengxiang rose extract, a mung bean extract, a green tea extract, a star anise extract, an astragalus membranaceus root extract, a ginseng root extract, a tricholoma matsutake extract, a radix arnebiae extract, a chamomile extract, a tree moss extract and a honeysuckle extract. The conditioning lotion has the characteristics of safety and no toxicity, moisturizing, and the like. The invention also provides a preparation method of the conditioning lotion containing cordyceps militaris ingredients. The preparation method is simple and has the effect that the production cost is effectively reduced.

Description

A kind of conditioning containing Cordyceps militaris (L.) Link. composition is revealed and preparation method thereof
Technical field
The present invention relates to cosmetic field, particularly relate to a kind of conditioning containing Cordyceps militaris (L.) Link. composition and reveal and preparation method thereof.
Background technology
Cordyceps militaris (L.) Link. formal name used at school Cordyceps militaris (L.) Link. ( cordyceps militaris), it and Cordyceps of Qinghai Province belong to Eumycota Ascomycotina Cordyceps, therefore, are called belonging to together " brother " of Cordyceps by expert.The perfect stage of Cordyceps militaris (L.) Link. life cycle comprises mycelial growth and sporophore growth.The insect larvaes such as Lepidoptera, coleoptera, Diptera or pupa infect the spore of Paecilomyces varioti, and when environmental condition is suitable for, spore just sprouts formation mycelium, and mycelium draws the nutrition in worm (pupa) body as the material of its growth promoter and the energy.After mycelia decomposes the various tissue in worm (pupa) body and organ, hyphostoma development transfers reproductive growth to by nourishing and growing, mycelium twist together gradually be differentiated to form sclerotium and pass that the external top becoming crocus or Chinese red is slightly expanded, in bar-shaped Stroma (sporophore), the many heads from polypide of Stroma, chest, caudad etc. stretch out.
Wild Cordyceps militaris (L.) Link. is similar to traditional Cordyceps, very rare at occurring in nature.Most research is thought, Cordyceps militaris (L.) Link. is close with natural cordyceps on active ingredient, and its medicinal and edibility can match in excellence or beauty with natural Cordyceps.The Cordyceps militaris (L.) Link. cellulose content of factorial praluction is higher than natural cordyceps, and the content of its protein, aminoacid, vitamin and trace element has has all met or exceeded the level of natural cordyceps.Plant in Cordyceps reported more than 350, Cordyceps militaris (L.) Link. is the rare Cordyceps that can form a large amount of cordycepin.Because with Cordyceps sibship recently, effective ingredient is quite even higher, and can artificial culture, Cordyceps militaris (L.) Link. becomes the Ideal Substitute of natural cordyceps.Riched Cordyceps Militaris is containing various bioactivators, as Cordyceps polysaccharide, cordycepin, cordycepic acid, SOD enzyme, adenosine, polypeptide/aminoacid, mannitol etc., with the cosmetics that Cordyceps militaris (L.) Link. extract is made for raw material, then there is antioxidation, defying age and the effect such as nutrition, check melanin synthesis is provided, extra-nutrition can be produced to human skin, improve coarse, effect such as enhancing elasticity, moisturizing whitening etc.
To increase due to the age and the various factors such as seasonal variations, ultraviolet radiation, smoking, operating pressure are large, sitting before computer, television set, contact radioactive substance causes the skin problem of people, as skin corium subside, moisture-retaining capacity declines, xerosis cutis is aging.Therefore, cosmetics have become the requisite articles for daily use of one of people.Conditioning dew, as the cosmetics with conditioning functions, is more and more used by people, but conditioning dew commercially available is at present of a great variety, and functional effect differs, and mostly with the addition of chemical composition skin being had to stimulation.Therefore, need exploitation badly a kind of containing large number of biological active component, existing good result of use, the healthy Novel conditioning dew of consumer can not be damaged again.
Summary of the invention
For the problems referred to above, the invention provides a kind of conditioning containing Cordyceps militaris (L.) Link. composition and reveal and preparation method thereof, there is safety non-toxic, crease-resistant feature, and production cost is lower.
For realizing above-mentioned purpose of the present invention, the invention provides a kind of conditioning containing Cordyceps militaris (L.) Link. composition and revealing, be by A, B1, B2, C, D and component E raw materials by weight portion formulated.
Component A: pure water 25-35 part, card ripple U-20 0.12-0.18 part.
B1 component: pure water 51-69 part, hydroxyethyl-cellulose 0.042-0.058 part.
B2 component: silk sliding natto gum 0.08-0.12 part, magnificent 1% solution in HA(micromolecule sea) 0.042-0.058 part, glycerol 1.7-2.3 part, glycyrrhizic acid dipotassium 2.5-3.5 part.
Component C: butanediol 4.2-5.8 part, Nipagin ester 0.25-0.35 part, scutellariae,radix extract 0.05-0.07 part, Cremophor RH40 0.42-0.58 part, essence 0.3-0.8 part.
D component: 10% potassium hydroxide 0.34-0.46 part.
Component E: Cellular respiration factor 0.42-0.58 part, Cordyceps extract 0.42-0.58 part, Aloe fermented product 0.25-0.35 part, hydrolysis Lac regis apis 0.1-0.3 part, Herba portulacae extract 0.1-0.3 part, Folium Kaki extract 0.1-0.3 part, orange peel extract 0.01-0.1 part, phellinus linteus extract 0.01-0.1 part, Salix Babylonica L.P.E 0.01-0.03 part, vanilla extract 0.01-0.03 part, Lengxiang rose flower extract 0.01-0.03 part, Semen phaseoli radiati extract 0.01-0.03 part, green tea extract 0.01-0.03 part, Fructus Anisi Stellati extract 0.01-0.02 part, pod membrane astragalus root extract 0.01-0.02 part, Radix Ginseng extract 0.01-0.02 part, tricholoma matsutake 0.01-0.02 part, Radix Arnebiae extract 0.01-0.02 part, camomile extract 0.01-0.02 part, tree moss extract 0.01-0.02 part, Flos Lonicerae extract 0.01-0.02 part.
In described component E, the preparation method of Cordyceps extract is: get Powdered or original state Cordyceps militaris (L.) Link.sporophore 40-100g, add alkali ion water 100-300ml, mixed liquor is obtained after concussion (100-300rpm) 10-50min, described mixed liquor is through collected after centrifugation centrifuged supernatant, gained primary deposition thing adds 100-300ml alkali ion water again and carries out second extraction, extracts three times altogether successively; Merge three centrifuged supernatant and the concentrated solution of concentrated 20-30ml, the dehydrated alcohol adding concentrated solution 2-4 times amount makes it under 4 DEG C of conditions, precipitate 8-12h, incline and supernatant and obtain precipitate, this precipitate absolute ethanol washing, freeze-day with constant temperature at a certain temperature between 10 DEG C-20 DEG C, obtain polysaccharide crude, be Cordyceps extract.
Described alkali ion water is by carrying out electrolysis generation by pure water.
Described alkali ion water index is pH:9.80-13.80, current potential: >=-120mV.
The preparation method of described component E Aloe fermented product is as follows.
(1) surface cleaning: Fresh leaf of aloe clear water wash clean, described clear water can not use the tap water containing bleach, because bleach can cause aloe liquid variable color, go bad.
(2) ultraviolet radiation sterilization: after the Fresh leaf of aloe of wash clean dries, be transported into preparation of samples room, described preparation of samples room is sterilizing room (indoor have sterilizer), carries out uv light irradiation sterilization 5-30min.
(3) remove leaf skin: in sterilizing room, remove Fresh leaf of aloe leaf skin, cut open crust with the blade of sterilization, and aloe gel juice is taken out; Gel juice and Ye Pi are respectively charged into Plastic Drum.
(4) high speed pulverization and precipitation: leaf skin tissue mashing, become dilute slurry with high speed disintegrator (rotating speed 10000-30000, time 0.2-5 minute); Then precipitation process is carried out; Namely supernatant becomes Folium Aloe natural juice.
(5) preparation of Aloe fermented product: described Aloe fermented product comprises Aloe gel fermented product and Folium Aloe fermented product.
1., be culture medium with aloe gel juice, take Hansenula anomala as inoculation strain, the inoculum concentration 1%-10%(percent by volume of bacterium liquid).Fermentation temperature 26 DEG C-31 DEG C, fermentation time is 20-30 days, and gained fermented product is Aloe gel fermented product.
2., with Folium Aloe natural juice for culture medium, take Hansenula anomala as inoculation strain, the inoculum concentration 1%-10%(percent by volume of bacterium liquid).Fermentation temperature 26 DEG C-31 DEG C, fermentation time is 20-30 days, and gained fermented product is Folium Aloe fermented product.
Described Herba portulacae extract, Folium Kaki extract, orange peel extract, scutellariae,radix extract, phellinus linteus extract, Salix Babylonica L.P.E, vanilla extract, Lengxiang rose flower extract, Semen phaseoli radiati extract, green tea extract, Fructus Anisi Stellati extract, pod membrane astragalus root extract, Radix Ginseng extract, tricholoma matsutake, Radix Arnebiae extract, camomile extract, tree moss extract, the preparation method of Flos Lonicerae extract is: get pulverous Herba Portulacae respectively, Folium Kaki, orange peel, scutellariae,radix, Phellinus igniarius (L. ex Fr.) Quel., salicis, Rhizoma et radix valerianae, Lengxiang rose flower, Semen phaseoli radiati, green tea, Fructus Anisi Stellati, pod membrane astragalus root, Radix Ginseng, Trichotoma matsutake, Radix Arnebiae (Radix Lithospermi), Flos Matricariae chamomillae, tree moss, Flos Lonicerae, mixed liquor is obtained after adding alkali ion water concussion respectively, described mixed liquor is through collected after centrifugation centrifuged supernatant, gained primary deposition thing adds alkali ion water respectively again and carries out second extraction, extract three times altogether successively, merge three centrifuged supernatant and concentrate to obtain concentrated solution, namely obtaining Herba portulacae extract, Folium Kaki extract, orange peel extract, scutellariae,radix extract, phellinus linteus extract, Salix Babylonica L.P.E, vanilla extract, Lengxiang rose flower extract, Semen phaseoli radiati extract, green tea extract, Fructus Anisi Stellati extract, pod membrane astragalus root extract, Radix Ginseng extract, tricholoma matsutake, Radix Arnebiae extract, camomile extract, tree moss extract, Flos Lonicerae extract respectively.
The preparation method that the present invention also provides a kind of conditioning containing Cordyceps militaris (L.) Link. composition to reveal, comprises the following steps.
Step one, component A raw material added the first blending tank and stir and be warming up to 80-90 DEG C and keep 20 minutes.
Step 2, B1 and B2 component raw material added the second blending tank and stir intensification 80 DEG C and keep 20 minutes.
Step 3, the first blending tank Raw suction homogenizing tank to be stirred, then the raw material in the second blending tank to be added in homogenizing tank.
Step 4, emulsifying, after 5 minutes, stir and are cooled to 60 DEG C.
Step 5, to add component C raw material stirring even, continues to be cooled to 45 DEG C.
Step 6, stir after be cooled to 35-38 DEG C, add D component raw material and regulate pH6.0-7.0, then it is even to add component E raw material stirring, ageing 24 hours, fill, subpackage is also packed, and is finished product.
Compared with prior art beneficial effect of the present invention.
The invention provides a kind of conditioning containing Cordyceps militaris (L.) Link. composition to reveal and preparation method thereof, the described dew of the conditioning containing Cordyceps militaris (L.) Link. composition is containing Aloe fermented product, Cordyceps extract, hydrolysis Lac regis apis, Herba portulacae extract, Folium Kaki extract, orange peel extract, scutellariae,radix extract, phellinus linteus extract, Salix Babylonica L.P.E, vanilla extract, Lengxiang rose flower extract, Semen phaseoli radiati extract, green tea extract, Fructus Anisi Stellati extract, pod membrane astragalus root extract, Radix Ginseng extract, tricholoma matsutake, Radix Arnebiae extract, camomile extract, tree moss extract, Flos Lonicerae extract 21 kinds of active component.Wherein Aloe fermented product has elimination scytitis and antibacterial action, and can significantly improve the anti-wrinkle effect of conditioning dew, is especially applicable to middle and aged women and uses.Herba Portulacae contains abundant SL3 fatty acid and vitamin A sample material.SL3 fatty acid forms the necessary material of cell membrane; Vitamin A sample substance maintains epithelial tissue as the normal function of skin, cornea.Orange peel extract contains terpenoid substance, plays antibacterial and natural perfume material.Containing a large amount of tannic acid in Folium Kaki, can effectively kill various antibacterial and fungus, there is effect that is clean and skin care.Lac regis apis rich in proteins, the material such as aminoacid, vitamin, lipoid, certain herbaceous plants with big flowers acetic acid, trace element, folic acid, acetylcholine, nucleic acid, has the effects such as regulation of skin metabolism and antioxidation.Scutellariae,radix extract is rich in flavone compound, has the effects such as antibacterial and contraction.To sum up, the present invention reveals the feature with safety non-toxic containing the conditioning of Cordyceps militaris (L.) Link. composition, and raw material is easy to get, and preparation method is simple, and production cost is lower.
Detailed description of the invention
The present invention is further described below in conjunction with specific embodiment.
The invention provides a kind of conditioning containing Cordyceps militaris (L.) Link. composition to reveal, be by A, B1, B2, C, D and component E raw materials by weight portion formulated.
Component A: pure water 30 parts, card ripple U-20 0.15 part.
B1 component: pure water 60.04 parts, hydroxyethyl-cellulose 0.05 part.
B2 component: the sliding natto gum 0.1 part of silk, magnificent 1% solution in HA(micromolecule sea) 0.05 part, glycerol 2 parts, glycyrrhizic acid dipotassium 3 parts.
Component C: butanediol 5 parts, Nipagin ester (PHENONIP) 0.3 part, scutellariae,radix extract 0.06 part, Cremophor RH40 0.5 part, 0.5 part, essence.
D component: 10% potassium hydroxide 0.4 part.
Component E: the Cellular respiration factor (CRF) 0.5 part, Cordyceps extract 0.5 part, Aloe fermented product 0.25 part, hydrolysis Lac regis apis 0.1 part, Herba portulacae extract 0.1 part, Folium Kaki extract 0.1 part, orange peel extract 0.05 part, phellinus linteus extract 0.01 part, Salix Babylonica L.P.E 0.01 part, vanilla extract 0.02 part, Lengxiang rose flower extract 0.01 part, Semen phaseoli radiati extract 0.01 part, green tea extract 0.02 part, Fructus Anisi Stellati extract 0.01 part, pod membrane astragalus root extract 0.01 part, Radix Ginseng extract 0.01 part, tricholoma matsutake 0.01 part, Radix Arnebiae extract 0.01 part, camomile extract 0.01 part, tree moss extract 0.01 part, Flos Lonicerae extract 0.01 part.
In described component E, the preparation method of Cordyceps extract is: get Powdered or original state Cordyceps militaris (L.) Link.sporophore 50g, add alkali ion water 100ml, concussion (200rpm) 30min, mixed liquor is through collected after centrifugation centrifuged supernatant, gained primary deposition thing adds 100ml alkali ion water again and carries out second extraction, extracts three times altogether successively; Merge three extracting solution and the concentrated solution of concentrated 30ml, the dehydrated alcohol adding concentrated solution 3 times amount makes it under 4 DEG C of conditions, precipitate 10h, inclines to supernatant and obtain precipitate, this precipitate absolute ethanol washing, dry under constant temperature 10 DEG C of conditions, obtain polysaccharide crude, be Cordyceps extract.
Described alkali ion water is by carrying out electrolysis generation by pure water; Described pure water is after electrolysis, and enrichment hydroxide ion in water near negative electrode, in alkalescence, obtains alkali ion water.
The alkali ion water index that described alkali ion water outlet produces is pH:9.80-13.80, current potential: >=-120mv.
With distilled water extraction Cordyceps militaris (L.) Link.sporophore effective ingredient, extraction efficiency is 17%, and the extraction efficiency of alkali ion water is 23%.As can be seen here, described alkali ion water extraction Cordyceps militaris (L.) Link.sporophore effective ingredient has not only increased substantially extraction efficiency, also avoid the pollution because using chemical solvent to bring.
The preparation method of described component E Aloe fermented product.
(1) surface cleaning: first Fresh leaf of aloe clear water wash clean, described clear water can not use the tap water containing bleach, because bleach can cause aloe liquid variable color, go bad.
(2) ultraviolet irradiation sterilization: after the Fresh leaf of aloe of wash clean dries, be transported into preparation of samples room, described preparation of samples room is sterilizing room (indoor have sterilizer), carries out uv light irradiation sterilization 6min.
(3) remove leaf skin: in sterilizing room, remove Folium Aloe skin, cut open crust with the blade of sterilization, and aloe gel juice is taken out; Gel juice and Ye Pi are respectively charged into Plastic Drum.
(4) high speed pulverization and precipitation: leaf skin tissue mashing, become dilute slurry with high speed disintegrator (rotating speed 20000, time 3 minutes); Then precipitation process is carried out; Namely supernatant becomes Folium Aloe natural juice.
(5) preparation of Aloe fermented product: described Aloe fermented product comprises Aloe gel fermented product and Folium Aloe fermented product.
1. be, with aloe gel juice culture medium, with Hansenula anomala (lot number: AS2.297, Bei Nuo bio tech ltd, Shanghai) for inoculation strain, inoculum concentration 4%(percent by volume).Fermentation temperature 28 DEG C, fermentation time is 25 days, and gained fermented product is Aloe gel fermented product.
2., with Folium Aloe natural juice for culture medium, with Hansenula anomala (lot number: AS2.297, Bei Nuo bio tech ltd, Shanghai) for inoculation strain, inoculum concentration 4%(percent by volume).Fermentation temperature 28 DEG C, fermentation time is 25 days, and gained fermented product is Folium Aloe fermented product.
Prior art commonly uses Aloe original juice, and the present invention adopts Aloe fermented product, and this Aloe fermented product has following benefit compared with the Aloe original juice not through fermenting: composition is more various and molecule is less, thus is more easily absorbed by the skin.
Described Herba portulacae extract, Folium Kaki extract, orange peel extract, scutellariae,radix extract, phellinus linteus extract, Salix Babylonica L.P.E, vanilla extract, Lengxiang rose flower extract, Semen phaseoli radiati extract, green tea extract, Fructus Anisi Stellati extract, pod membrane astragalus root extract, Radix Ginseng extract, tricholoma matsutake, Radix Arnebiae extract, camomile extract, tree moss extract, the preparation method of Flos Lonicerae extract is: get pulverous Herba Portulacae respectively, Folium Kaki, orange peel, scutellariae,radix, Phellinus igniarius (L. ex Fr.) Quel., salicis, Rhizoma et radix valerianae, Lengxiang rose flower, Semen phaseoli radiati, green tea, Fructus Anisi Stellati, pod membrane astragalus root, Radix Ginseng, Trichotoma matsutake, Radix Arnebiae (Radix Lithospermi), Flos Matricariae chamomillae, tree moss, Flos Lonicerae, mixed liquor is obtained after adding alkali ion water concussion respectively, described mixed liquor is through collected after centrifugation centrifuged supernatant, gained primary deposition thing adds alkali ion water respectively again and carries out second extraction, extract three times altogether successively, merge three centrifuged supernatant and concentrate to obtain concentrated solution, namely obtaining Herba portulacae extract, Folium Kaki extract, orange peel extract, scutellariae,radix extract, phellinus linteus extract, Salix Babylonica L.P.E, vanilla extract, Lengxiang rose flower extract, Semen phaseoli radiati extract, green tea extract, Fructus Anisi Stellati extract, pod membrane astragalus root extract, Radix Ginseng extract, tricholoma matsutake, Radix Arnebiae extract, camomile extract, tree moss extract, Flos Lonicerae extract respectively.
The preparation method that the present invention also provides a kind of conditioning containing Cordyceps militaris (L.) Link. composition to reveal, comprises the following steps.
Step one, component A raw material added the first blending tank and stir and be warming up to 80 DEG C and keep 20 minutes.
Step 2, B1 and B2 component raw material added the second blending tank and stir intensification 80 DEG C and keep 20 minutes.
Step 3, the first blending tank Raw suction homogenizing tank to be stirred, then the raw material in the second blending tank to be added in homogenizing tank.
Step 4, emulsifying, after 5 minutes, stir and are cooled to 60 DEG C.
Step 5, to add component C raw material stirring even, continues to be cooled to 45 DEG C.
Step 6, stir after be cooled to 35 DEG C, add D component raw material and regulate pH to be 6.0, then it is even to add component E raw material stirring, ageing 24 hours, fill, subpackage is also packed, and is finished product.
The efficacy assessments of the present embodiment formula composition and preparation method thereof gained conditioning dew product.
1, practical effect evaluation: participating in conditioning dew effect evaluation and test interviewee number is 33 people, using the present embodiment containing conditioning dew every day each 1 time sooner or later of Cordyceps militaris (L.) Link. composition, 30 days is a course for the treatment of.After a course for the treatment of is revealed in the conditioning using the present embodiment to contain Cordyceps militaris (L.) Link. composition, objective evaluation is made to the moisturizing of this conditioning dew, moisturizing, trap, stretchability, viscosity, abnormal smells from the patient, often kind of effect judgment criteria is divided into third gear, wherein moisturizing: first grade is that moistening effect is very good, second gear is that moistening effect is general, and third gear is that moistening effect is bad; Moisturizing: first grade for moisturizing effect clearly, second gear is that moisturizing effect is general, and third gear is that moisturizing effect is bad; Trap: first grade is easy to absorb for elite, and second gear is that elite assimilation effect is general, and third gear is that elite assimilation effect is bad; Stretchability: first grade is that stretchability is very good, second gear is that stretchability is general, and third gear is that stretchability is bad; Viscosity: first grade is that viscosity is very good, second gear is that viscosity is general, and third gear is that viscosity is bad; Abnormal smells from the patient: first grade is natural comfortable, second gear is that chemical reagent is obvious, and third gear is not for having peculiar taste.Concrete evaluation result is in table 1.
Table 1: the present invention is containing the conditioning dew result of use evaluation of Cordyceps militaris (L.) Link. composition.
First grade Second gear Third gear
Moisturizing 9 21 3
Moisturizing 12 9 12
Trap 21 9 3
Stretchability 24 6 3
Viscosity 15 18 0
Abnormal smells from the patient 21 0 12
As shown in Table 1, the present invention has good moisturizing, moisturizing, nutritive validity containing the conditioning dew of Cordyceps militaris (L.) Link. composition.
2, senile-resistant efficacy evaluation: senile-resistant efficacy evaluation adopts in-vitro evaluation method, and working sample is to the Scavenging activity of free radical.Comprise three indexs, be respectively: remove the mensuration of DPPH ability, remove the mensuration of superoxide anion ability and the mensuration of scavenging hydroxyl ability.
In the mensuration removing DPPH ability, the clearance rate that the present embodiment reveals containing the conditioning of Cordyceps militaris (L.) Link. composition is 24.93%-42.44%; In the mensuration removing superoxide anion ability, the conditioning dew that the present embodiment contains Cordyceps militaris (L.) Link. composition is 20.61%-43.46% to the suppression ratio of superoxide anion; In the mensuration of scavenging hydroxyl ability, the conditioning dew that the present embodiment contains Cordyceps militaris (L.) Link. composition is 15.38%-23.13% to the clearance rate of hydroxy radical.
3, pH value measures: take conditioning dew sample 1g(and be accurate to 0.1g), adding distil water 10g, is heated to 40 DEG C, and is constantly stirred to evenly, measures after being cooled to room temperature with pH meter.
Measuring the pH value that the present embodiment reveals containing the conditioning of Cordyceps militaris (L.) Link. composition is 6.5-7.0.

Claims (5)

1. the conditioning containing Cordyceps militaris (L.) Link. composition is revealed, and is formed by A, B1, B2, C, D and component E preparation of raw material:
Component A: pure water 25-35 part, card ripple U-20 0.12-0.18 part;
B1 component: pure water 51-69 part, hydroxyethyl-cellulose 0.042-0.058 part;
B2 component: silk sliding natto gum 0.08-0.12 part, magnificent 1% solution in HA(micromolecule sea) 0.042-0.058 part, glycerol 1.7-2.3 part, glycyrrhizic acid dipotassium 2.5-3.5 part;
Component C: butanediol 4.2-5.8 part, Nipagin ester 0.25-0.35 part, scutellariae,radix extract 0.05-0.07 part, Cremophor RH40 0.42-0.58 part, essence 0.3-0.8 part;
D component: 10% potassium hydroxide 0.34-0.46 part;
Component E: Cellular respiration factor 0.42-0.58 part, Cordyceps extract 0.42-0.58 part, Aloe fermented product 0.25-0.35 part, hydrolysis Lac regis apis 0.1-0.3 part, Herba portulacae extract 0.1-0.3 part, Folium Kaki extract 0.1-0.3 part, orange peel extract 0.01-0.1 part, phellinus linteus extract 0.01-0.1 part, Salix Babylonica L.P.E 0.01-0.03 part, vanilla extract 0.01-0.03 part, Lengxiang rose flower extract 0.01-0.03 part, Semen phaseoli radiati extract 0.01-0.03 part, green tea extract 0.01-0.03 part, Fructus Anisi Stellati extract 0.01-0.02 part, pod membrane astragalus root extract 0.01-0.02 part, Radix Ginseng extract 0.01-0.02 part, tricholoma matsutake 0.01-0.02 part, Radix Arnebiae extract 0.01-0.02 part, camomile extract 0.01-0.02 part, tree moss extract 0.01-0.02 part, Flos Lonicerae extract 0.01-0.02 part,
In described D component, the preparation method of Cordyceps extract is: get Powdered or original state Cordyceps militaris (L.) Link.sporophore 40-100g, add alkali ion water 100-300ml, mixed liquor is obtained after concussion (100-300rpm) 10-50min, described mixed liquor is through collected after centrifugation centrifuged supernatant, gained primary deposition thing adds 100-300ml alkali ion water again and carries out second extraction, extracts three times altogether successively; Merge three centrifuged supernatant and the concentrated solution of concentrated 20-30ml, the dehydrated alcohol adding concentrated solution 2-4 times amount makes it under 4 DEG C of conditions, precipitate 8-12h, incline and supernatant and obtain precipitate, this precipitate absolute ethanol washing, freeze-day with constant temperature at a certain temperature between 10 DEG C-20 DEG C, obtain polysaccharide crude, be Cordyceps extract;
In described component E, the preparation method of Aloe fermented product is:
(1) surface cleaning: Fresh leaf of aloe clear water wash clean;
(2) ultraviolet radiation sterilization: after the Fresh leaf of aloe of wash clean dries, be transported into preparation of samples room, described preparation of samples room is sterilizing room (indoor have sterilizer), carries out uv light irradiation sterilization 5-30min;
(3) remove leaf skin: in sterilizing room, remove Fresh leaf of aloe leaf skin, cut open crust with the blade of sterilization, and aloe gel juice is taken out; Gel juice and Ye Pi are respectively charged into Plastic Drum;
(4) high speed pulverization and precipitation: leaf skin tissue mashing, become dilute slurry with high speed disintegrator (rotating speed 10000-30000, time 0.2-5 minute); Then precipitation process is carried out; Namely supernatant becomes Folium Aloe natural juice;
(5) preparation of Aloe fermented product: described Aloe fermented product comprises Aloe gel fermented product and Folium Aloe fermented product;
1., be culture medium with aloe gel juice, take Hansenula anomala as inoculation strain, the inoculum concentration 1%-10% of bacterium liquid, fermentation temperature 26 DEG C-31 DEG C, fermentation time is 20-30 days, and gained fermented product is Aloe gel fermented product;
2., with Folium Aloe natural juice for culture medium, take Hansenula anomala as inoculation strain, the inoculum concentration 1%-10% of bacterium liquid, fermentation temperature 26 DEG C-31 DEG C, fermentation time is 20-30 days, and gained fermented product is Folium Aloe fermented product;
Described Herba portulacae extract, Folium Kaki extract, orange peel extract, scutellariae,radix extract, phellinus linteus extract, Salix Babylonica L.P.E, vanilla extract, Lengxiang rose flower extract, Semen phaseoli radiati extract, green tea extract, Fructus Anisi Stellati extract, pod membrane astragalus root extract, Radix Ginseng extract, tricholoma matsutake, Radix Arnebiae extract, camomile extract, tree moss extract, the preparation method of Flos Lonicerae extract is: get pulverous Herba Portulacae respectively, Folium Kaki, orange peel, scutellariae,radix, Phellinus igniarius (L. ex Fr.) Quel., salicis, Rhizoma et radix valerianae, Lengxiang rose flower, Semen phaseoli radiati, green tea, Fructus Anisi Stellati, pod membrane astragalus root, Radix Ginseng, Trichotoma matsutake, Radix Arnebiae (Radix Lithospermi), Flos Matricariae chamomillae, tree moss, Flos Lonicerae, mixed liquor is obtained after adding alkali ion water concussion respectively, described mixed liquor is through collected after centrifugation centrifuged supernatant, gained primary deposition thing adds alkali ion water respectively again and carries out second extraction, extract three times altogether successively, merge three centrifuged supernatant and concentrate to obtain concentrated solution, namely obtaining Herba portulacae extract, Folium Kaki extract, orange peel extract, scutellariae,radix extract, phellinus linteus extract, Salix Babylonica L.P.E, vanilla extract, Lengxiang rose flower extract, Semen phaseoli radiati extract, green tea extract, Fructus Anisi Stellati extract, pod membrane astragalus root extract, Radix Ginseng extract, tricholoma matsutake, Radix Arnebiae extract, camomile extract, tree moss extract, Flos Lonicerae extract respectively.
2. revealing containing the conditioning of Cordyceps militaris (L.) Link. composition as claimed in claim 1, it is characterized in that, is formed by A, B1, B2, C, D and component E preparation of raw material:
Component A: pure water 30 parts, card ripple U-20 0.15 part;
B1 component: pure water 60.04 parts, hydroxyethyl-cellulose 0.05 part;
B2 component: the sliding natto gum 0.1 part of silk, magnificent 1% solution in HA(micromolecule sea) 0.05 part, glycerol 2 parts, glycyrrhizic acid dipotassium 3 parts;
Component C: butanediol 5 parts, Nipagin ester 0.3 part, scutellariae,radix extract 0.06 part, Cremophor RH40 0.5 part, 0.5 part, essence;
D component: 10% potassium hydroxide 0.4 part;
Component E: the Cellular respiration factor 0.5 part, Cordyceps extract 0.5 part, Aloe fermented product 0.25 part, hydrolysis Lac regis apis 0.1 part, Herba portulacae extract 0.1 part, Folium Kaki extract 0.1 part, orange peel extract 0.05 part, phellinus linteus extract 0.01 part, Salix Babylonica L.P.E 0.01 part, vanilla extract 0.02 part, Lengxiang rose flower extract 0.01 part, Semen phaseoli radiati extract 0.01 part, green tea extract 0.02 part, Fructus Anisi Stellati extract 0.01 part, pod membrane astragalus root extract 0.01 part, Radix Ginseng extract 0.01 part, tricholoma matsutake 0.01 part, Radix Arnebiae extract 0.01 part, camomile extract 0.01 part, tree moss extract 0.01 part, Flos Lonicerae extract 0.01 part,
In described component E, the preparation method of Cordyceps extract is: get Powdered or original state Cordyceps militaris (L.) Link.sporophore 50g, add alkali ion water 100ml, concussion (200rpm) 30min, mixed liquor is through collected after centrifugation centrifuged supernatant, gained primary deposition thing adds 100ml alkali ion water again and carries out second extraction, extracts three times altogether successively; Merge three extracting solution and the concentrated solution of concentrated 30ml, the dehydrated alcohol adding concentrated solution 3 times amount makes it under 4 DEG C of conditions, precipitate 10h, inclines to supernatant and obtain precipitate, this precipitate absolute ethanol washing, dry under constant temperature 10 DEG C of conditions, obtain polysaccharide crude, be Cordyceps extract;
In described component E, the preparation method of Aloe fermented product is:
(1) surface cleaning: Fresh leaf of aloe clear water wash clean;
(2) ultraviolet irradiation sterilization: after the Fresh leaf of aloe of wash clean dries, be transported into preparation of samples room, described preparation of samples room is sterilizing room (indoor have sterilizer), carries out uv light irradiation sterilization 6min;
(3) remove leaf skin: in sterilizing room, remove Folium Aloe skin, cut open crust with the blade of sterilization, and aloe gel juice is taken out; Gel juice and Ye Pi are respectively charged into Plastic Drum;
(4) high speed pulverization and precipitation: leaf skin tissue mashing, become dilute slurry with high speed disintegrator (rotating speed 20000, time 3 minutes); Then precipitation process is carried out; Namely supernatant becomes Folium Aloe natural juice;
(5) preparation of Aloe fermented product: described Aloe fermented product comprises Aloe gel fermented product and Folium Aloe fermented product;
1., be culture medium with aloe gel juice, take Hansenula anomala as inoculation strain, inoculum concentration 4%, fermentation temperature 28 DEG C, fermentation time is 25 days, and gained fermented product is Aloe gel fermented product;
2., with Folium Aloe natural juice for culture medium, take Hansenula anomala as inoculation strain, inoculum concentration 4%, fermentation temperature 28 DEG C, fermentation time is 25 days, and gained fermented product is Folium Aloe fermented product;
Described Herba portulacae extract, Folium Kaki extract, orange peel extract, scutellariae,radix extract, phellinus linteus extract, Salix Babylonica L.P.E, vanilla extract, Lengxiang rose flower extract, Semen phaseoli radiati extract, green tea extract, Fructus Anisi Stellati extract, pod membrane astragalus root extract, Radix Ginseng extract, tricholoma matsutake, Radix Arnebiae extract, camomile extract, tree moss extract, the preparation method of Flos Lonicerae extract is: get pulverous Herba Portulacae respectively, Folium Kaki, orange peel, scutellariae,radix, Phellinus igniarius (L. ex Fr.) Quel., salicis, Rhizoma et radix valerianae, Lengxiang rose flower, Semen phaseoli radiati, green tea, Fructus Anisi Stellati, pod membrane astragalus root, Radix Ginseng, Trichotoma matsutake, Radix Arnebiae (Radix Lithospermi), Flos Matricariae chamomillae, tree moss, Flos Lonicerae, mixed liquor is obtained after adding alkali ion water concussion respectively, described mixed liquor is through collected after centrifugation centrifuged supernatant, gained primary deposition thing adds alkali ion water respectively again and carries out second extraction, extract three times altogether successively, merge three centrifuged supernatant and concentrate to obtain concentrated solution, namely obtaining Herba portulacae extract, Folium Kaki extract, orange peel extract, scutellariae,radix extract, phellinus linteus extract, Salix Babylonica L.P.E, vanilla extract, Lengxiang rose flower extract, Semen phaseoli radiati extract, green tea extract, Fructus Anisi Stellati extract, pod membrane astragalus root extract, Radix Ginseng extract, tricholoma matsutake, Radix Arnebiae extract, camomile extract, tree moss extract, Flos Lonicerae extract respectively.
3. reveal containing the conditioning of Cordyceps militaris (L.) Link. composition as claimed in claim 1 or 2, it is characterized in that, described alkali ion water is by carrying out electrolysis generation by pure water.
4. reveal containing the conditioning of Cordyceps militaris (L.) Link. composition as claimed in claim 3, it is characterized in that, described alkali ion water index is pH:9.80-13.80, current potential: >=-120mV.
5., as claimed in claim 4 containing the preparation method that the conditioning of Cordyceps militaris (L.) Link. composition is revealed, it is characterized in that:
Step one, component A raw material added the first blending tank and stir and be warming up to 80-90 DEG C and keep 20 minutes;
Step 2, B1 and B2 component raw material added the second blending tank and stir intensification 80 DEG C and keep 20 minutes;
Step 3, the first blending tank Raw suction homogenizing tank to be stirred, then the raw material in the second blending tank is added in homogenizing tank;
Step 4, emulsifying, after 5 minutes, stir and are cooled to 60 DEG C;
Step 5, to add component C raw material stirring even, continues to be cooled to 45 DEG C;
Step 6, stir after be cooled to 35-38 DEG C, add D component raw material and regulate pH6.0-7.0, then it is even to add component E raw material stirring, ageing 24 hours, fill, subpackage is also packed, and is finished product.
CN201410684506.9A 2014-11-25 2014-11-25 Conditioning lotion containing cordyceps militaris ingredients and preparation method thereof Pending CN104367539A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108348435A (en) * 2016-09-28 2018-07-31 株式会社爱茉莉太平洋 Containing as active ingredient Cyanidin -3-O- glucosides and the anti-aging of natto gum use Dermatologic preparation composition
CN113116767A (en) * 2020-01-10 2021-07-16 广州市科能化妆品科研有限公司 Skin refreshing lotion, preparation method thereof and collagenase inhibitor

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104083318A (en) * 2014-07-09 2014-10-08 广州市攸澜化妆品有限公司 Skin-whitening cosmetic and preparation method thereof
CN104152514A (en) * 2014-07-24 2014-11-19 北京翰若生物科技有限公司 Origin fermentation method and origin fermentation product prepared by same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104083318A (en) * 2014-07-09 2014-10-08 广州市攸澜化妆品有限公司 Skin-whitening cosmetic and preparation method thereof
CN104152514A (en) * 2014-07-24 2014-11-19 北京翰若生物科技有限公司 Origin fermentation method and origin fermentation product prepared by same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
赵润等: ""冬虫夏草菌丝体液体培养基的优化"", 《天津师范大学学报(自然科学版)》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108348435A (en) * 2016-09-28 2018-07-31 株式会社爱茉莉太平洋 Containing as active ingredient Cyanidin -3-O- glucosides and the anti-aging of natto gum use Dermatologic preparation composition
CN113116767A (en) * 2020-01-10 2021-07-16 广州市科能化妆品科研有限公司 Skin refreshing lotion, preparation method thereof and collagenase inhibitor

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