CN104336593A - Ginseng, hairy antler and dendrobium health food and its making method - Google Patents
Ginseng, hairy antler and dendrobium health food and its making method Download PDFInfo
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- CN104336593A CN104336593A CN201310325630.1A CN201310325630A CN104336593A CN 104336593 A CN104336593 A CN 104336593A CN 201310325630 A CN201310325630 A CN 201310325630A CN 104336593 A CN104336593 A CN 104336593A
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- ginseng
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- 235000003140 Panax quinquefolius Nutrition 0.000 title claims abstract description 43
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- 235000013402 health food Nutrition 0.000 title claims abstract description 17
- 210000003056 antler Anatomy 0.000 title claims abstract description 11
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention provides a health food made from ginseng, hairy antler, wolfberry fruit and dendrobium, and its making method. The health food has the functions of immunity enhancing and muscle power fatigue alleviating, and has the advantages of reasonable making process, stable and controllable quality, and good social and economic benefits.
Description
Technical field
The present invention relates to a kind of health food and preparation method thereof, is exactly a kind of health food made for raw material with ginseng, cervus elaphus linnaeus, the fruit of Chinese wolfberry, the stem of noble dendrobium.
Background technology
Along with growth in the living standard, increasing people payes attention to nutrition and health care.Health food in the market, not proper due to compatibility and recipe quantity, affects its effect, and there is function singleness, acts on unconspicuous deficiency.Product of the present invention, according to theory of traditional Chinese medical science prescription, effect is remarkable, can play and strengthen immunity, physical-fatigue-relieving health effect preferably.
Ginseng is the dry root welding technology of Araliaceae ginseng Panax ginseng C.A.Mey., have reinforce vital energy, multiple arteries and veins takes off admittedly, reinforce the spleen to benefit the lung, promote the production of body fluid nourish blood, effect of intelligence development of calming the nerves.The good reputation that ginseng has since ancient times " kings of hundred grass ", is described as the superfine product of " enriching yin is mended raw, strengthens the body resistance to consolidate the constitution " by medical circle.Ginseng is containing multiple saponin and polysaccharide composition, and modern medicine study thinks to have strengthening by means of tonics, raising muscle power and mental labour ability, keeps fit, strengthens immunity, anti-ageing, cosmetology effect.Panaxan all has obvious facilitation to the specific immunity of body and nospecific immunity.
Cervus elaphus linnaeus is the young horn of the unossified close raw fine hair of stag of animal in deer family red deer Cervus elaphus Linnaeus, has invigorating kidney yang, benefiting essence-blood, strengthening the bones and muscles, adjusts punching to appoint, effect of holder sore.Its complicated, has 17 kinds with upper amino acid, 9 kinds of aliphatic acid, 10 kinds of phospholipid compositions and protein etc.Research shows, pilose antler have strong, improve body immunity, anti-oxidant and antidotal effect.
The fruit of Chinese wolfberry is the dry mature fruit of plant of Solanaceae lycium barbarum Lycium barbarum L., and its taste is sweet, the flat effect with liver-kidney tonifying of property.Research shows, fruit of Chinese wolfberry water extract can improve the quantity of tiring, can increase antibody forming cell of the phagocytic function of macrophage, the effect strengthening serum lysozyme, raising Serum Antibody, has and strengthens nospecific immunity effect.
The stem of noble dendrobium is orchid HERBA DENDROBII Dendrobium nobile Lindl., Dendrobium Chrysotoxum Lindl Dendrobium chrysotoxum Lindl. or the cultivation product of Dendrobium fimbriatum Hook Dendrobium fimbriatum Lindl. and the fresh or dry stem of congener allied species thereof, with glossy ganoderma, ginseng, Cordyceps sinensis etc. are listed in top grade Chinese medicine.There is reinforcing stomach reg fluid, nourishing Yin and clearing heat effect.Research shows, have obvious facilitation to the function of peritoneal macrophage, polysaccharide has immunocompetence, and alkaloid has anti-inflammatory, immunological regulation, the effect of cholinomimetic excitor nerve, and phenols has anti peroxidation of lipid, effect of scavenging radical.
Product of the present invention by the ginseng of above-mentioned " medicine-food two-purpose " and " can be used for health food ", cervus elaphus linnaeus, the fruit of Chinese wolfberry, the stem of noble dendrobium through extracting the health food made, there is the function strengthening immunity, alleviating physical fatigue, there are no the report of proportioning identical with the Main Ingredients and Appearance of product of the present invention.
Summary of the invention
The object of the invention is to: providing a kind of and have the health food strengthening immunity, alleviating physical fatigue function, is that raw material is made by ginseng, cervus elaphus linnaeus, the fruit of Chinese wolfberry, the stem of noble dendrobium.
Main Ingredients and Appearance proportioning of the present invention forms like this: according to listed as parts by weight, by ginseng 1 ~ 5 part, cervus elaphus linnaeus 0.1 ~ 1 part, the fruit of Chinese wolfberry 1 ~ 5 part, the stem of noble dendrobium 1 ~ 5 part.
Specifically, according to listed as parts by weight, by ginseng 2 ~ 4 parts, cervus elaphus linnaeus 0.5 ~ 1 part, the fruit of Chinese wolfberry 2 ~ 4 parts, the stem of noble dendrobium 2 ~ 4 parts.
Specifically, according to listed as parts by weight, it makes dried cream powder by ginseng 2 ~ 4 parts, cervus elaphus linnaeus 0.5 ~ 1 part, the fruit of Chinese wolfberry 2 ~ 4 parts, the stem of noble dendrobium 2 ~ 4 parts through extracting, and adds excipient or diluent, make tablet or capsule or soft capsule.
Specifically, according to listed as parts by weight, it makes medicinal extract by ginseng 2 ~ 4 parts, cervus elaphus linnaeus 0.5 ~ 1 part, the fruit of Chinese wolfberry 2 ~ 4 parts, the stem of noble dendrobium 2 ~ 4 parts through extracting, and adds diluent or flavor enhancement, make granule or oral liquid.
Wherein said excipient includes but not limited to: sweet mellow wine, PVP K30, microcrystalline cellulose, lactose.
Wherein said diluent includes but not limited to: edible oil, purified water.
Wherein said flavor enhancement includes but not limited to: citric acid, malic acid, lactic acid or tartaric acid; Sucrose, maltose, honey or mannitol.
The preparation method of ginseng and pilose antler stem of noble dendrobium health food of the present invention comprises the following steps:
1, get cervus elaphus linnaeus and be ground into fine powder, for subsequent use;
2, get people and participate in 4 ~ 8 times amount 70% alcohol refluxs extraction 2 ~ 3 times (being preferably 3 times), each 1 ~ 2 hour, filter, merging filtrate, reclaim ethanol and concentrate (density 50 DEG C surveys 1.10 ~ 1.20);
3, get the dregs of a decoction after the fruit of Chinese wolfberry, the stem of noble dendrobium and ginseng alcohol extract, add 5 ~ 10 times amount soak by water 2 ~ 3 times (being preferably 2 times), each 1 ~ 2 hour (being preferably 1.5 hours), filters, carries concentrate merge with panaxynol;
4, by the concentration of liquid medicine of step " 3 " to relative density be the thick paste of 1.20 ~ 1.30 (50 DEG C), mix with the cervus elaphus linnaeus fine powder of step " 1 ", dry, pulverize after mixing, add appropriate excipient or diluent, make tablet or capsule or soft capsule.
Step also can be:
1, get ginseng, cervus elaphus linnaeus adds 4 ~ 8 times amount 70% alcohol refluxs and extract 2 ~ 3 times (be preferably 3 times), each 1 ~ 2 hour, filter, merging filtrate, reclaim ethanol and concentrated (density 50 DEG C surveys 1.10 ~ 1.20);
2, get the dregs of a decoction after the fruit of Chinese wolfberry, the stem of noble dendrobium and step " 1 " alcohol extract, add 5 ~ 10 times amount soak by water 2 ~ 3 times (being preferably 2 times), each 1 ~ 2 hour (being preferably 1.5 hours), filters, merges with step " 1 " alcohol extracting concentrate;
3, get liquid after the merging of step " 2 ", add diluent or flavor enhancement after filtration, make granule or oral liquid.
Product of the present invention compares with the similar food product of being good for, and main innovation is as follows:
1, product of the present invention is by single for tradition famous and precious raw material, has carried out rational proportion according to theory of traditional Chinese medical science, and effect is remarkable, can play good health-care effect.
2, product of the present invention is studied through animal experiment, has obvious alleviating physical fatigue, strengthens immunization.Composition creates synergy, remarkable compared with the effect of any one single medicinal material.
3, product of the present invention contains several functions composition, with saponin(e and polysaccharide for quality control index, and steady quality; Through technical study and trial-production, rational technology is feasible; Economic and social benefit has good prospects.
For checking Product Process of the present invention is reasonable, matter reason is stable, applicant carried out series of experimental research, specific as follows:
1, technology and quality research on standard
1) alcohol extracting condition is preferred
With total saposins extracted amount for inspection target, design Three factors-levels orthogonal test, factor level sees the following form:
Result: optimum condition is combined as A
2b
1c
2, namely add 6 times amount 70% alcohol refluxs and extract twice, each 1.5 hours.
2) alcohol extracting demonstration test
Get ginseng 400g, add 6 times amount 70% alcohol refluxs and extract 3 times, each 1.5 hours, reclaim ethanol and drying, measure total saponin content, the results are shown in following table:
| Paste-forming rate (%) | Total saposins (g) | |
| 1 | 16.7 | 3.31 |
| 2 | 15.3 | 3.28 |
| 3 | 15.4 | 3.25 |
Three batches of tests show: alcohol extraction process is stablized feasible.
3) abstract methods is preferred
With Thick many candies extracted amount for inspection target, design Three factors-levels orthogonal test, factor level sees the following form:
Result: optimum condition is combined as A
2b
1c
2, namely add 10 times amount water extractions and get 2 times, each 1.5 hours.
4) alcohol extracting demonstration test
Get 3 parts of ginseng dregs of a decoction, add the stem of noble dendrobium, the fruit of Chinese wolfberry, add 10 times amount water extractions and get 2 times, each 1.5 hours, concentrate drying, measure Thick many candies extracted amount, the results are shown in following table:
| Paste-forming rate (%) | Thick many candies extracted amount (g) | |
| 1 | 24.5 | 3.32 |
| 2 | 23.6 | 2.98 |
| 3 | 23.9 | 3.11 |
Three batches of tests show: extraction process by water is stablized feasible.
5) make tablet according to prescription proportioning of the present invention and preparation technology, through three batches of trial-productions, its rational technology is feasible, and indices all meets the requirements after testing, and concrete outcome is as following table:
| Project | Index | 20121201 | 20121202 | 20121203 |
| Total saposins (g/100g) | ≥0.6％ | 0.72％ | 0.75％ | 0.73％ |
| Thick many candies (g/100g) | ≥0.8％ | 0.96％ | 0.92％ | 0.91％ |
| Disintegration time limited (min) | ≤60 | 30 | 25 | 30 |
| Arsenic (in As), mg/kg | ≤0.3 | ＜0.1 | ＜0.1 | ＜0.1 |
| Plumbous (in Pb), mg/g | ≤0.5 | ＜0.1 | ＜0.1 | ＜0.1 |
| Total plate count, CFU/g | ≤1000 | ＜100 | ＜100 | ＜100 |
| Coliform, MPN/100g | ≤40 | ＜1 | ＜1 | ＜1 |
| Mould, CFU/g | ≤25 | ＜10 | ＜10 | ＜10 |
| Pathogenic bacteria | Must not detect | Do not detect | Do not detect | Do not detect |
Illustrate: in table, data are only the detection of trial-production three batches of tablets, do not represent the quality control standard that product of the present invention is final.
2, immunological regulation experimental study
1) trial drug: make dried cream powder by the prescription of the present invention's " embodiment 1 " and technique.
2) animal used as test and raising: healthy ICR mouse 60, male and female half and half, body weight 19 ± 3g, tests after regular diet 5d.
3) experimental technique: according to daily 10g crude drug amount of being grown up, be converted to dried cream powder daily to measure, 0.0026 is taken advantage of to obtain mouse dose (add after normal saline becomes solution and take), respectively with the same dosage of single ginseng, single cervus elaphus linnaeus, the single fruit of Chinese wolfberry, single Herba Dendrobii extract as a control group, normal group takes physiological saline.Each group of continuous gavage 5d, after last administration 24h, mouse tail vein injects prepared Chinese ink, gets blood respectively after 12min from eyeground, measures OD value, and claims liver and spleen weight, calculates and cleans up index, the results are shown in following table (n=10 X ± S):
Note: compare with normal group, * P < 0.05**P < 0.01
Result shows: product of the present invention can improve the phagocytic function of the netted chrotoplast of mouse monokaryon, there is good immunoloregulation function, and than control group 1 (single ginseng), control group 2 (single cervus elaphus linnaeus), control group 3 (the single fruit of Chinese wolfberry), control group 4 (the single stem of noble dendrobium) effect by force, composition creates synergy, and comparatively any one single medicinal material is all effective.
3, antifatigue experimental study
1) trial drug: prescription and the technique of the present invention's " embodiment 1 " make dried cream powder, according to daily 10g crude drug amount of being grown up, be converted to dried cream powder daily to measure, take advantage of 0.0026 to obtain mouse dose, add normal saline and become solution (high, medium and low dosage).
2) animal used as test and raising: healthy ICR mouse 60, male and female half and half, body weight 20 ± 2g, tests after regular diet 5d.
3) experimental technique: respectively with the same dosage of single ginseng, single cervus elaphus linnaeus, the single fruit of Chinese wolfberry, single Herba Dendrobii extract as a control group, each group of continuous gavage 30d, 2h after last administration, depth of water 30cm water temperature 25 ~ 28 DEG C of tank went swimmings are put into by 5% heavy burden sheet lead of Mouse Weight, record starts to the death time, the results are shown in following table (n=10 X ± S):
Note: compare with normal group, * P < 0.05**P < 0.01
Result shows: product of the present invention can extend mouse swimming time, significant difference is had with normal group ratio, and than control group 1 (single ginseng), control group 2 (single cervus elaphus linnaeus), control group 3 (the single fruit of Chinese wolfberry), control group 4 (the single stem of noble dendrobium) effect by force, composition creates synergy, and comparatively any one single medicinal material is all effective.
Detailed description of the invention
Embodiments of the invention 1:
1) get cervus elaphus linnaeus 1kg, be ground into fine powder, for subsequent use after crossing 80 mesh sieves;
2) get ginseng 4kg, add 6 times amount 70% alcohol refluxs and extract 3 times, each 1.5 hours, filter, merging filtrate, reclaim ethanol, being concentrated into density is 1.10 ~ 1.20 (50 DEG C of surveys);
3) get the dregs of a decoction after fruit of Chinese wolfberry 4kg, stem of noble dendrobium 4kg and ginseng alcohol extract, add water 10 times amount soak by water 2 times, each 1.5 hours, filters, carry concentrate merges with panaxynol, is condensed into thick paste (50 DEG C of survey density are 1.20 ~ 1.30);
4) cervus elaphus linnaeus fine powder is admixed thick paste, drying under reduced pressure (60 ~ 80 DEG C), obtains dry extract, is ground into fine powder;
5) get sweet mellow wine 4kg mix with the dried cream powder of " step 4) ", the ethanol adding appropriate PVP is made softwood and is made particle (or making particle by spray-on process), dry compressing tablet afterwards, and control strip is heavily 0.4 ~ 0.5g, film coating and get final product.
Embodiments of the invention 2:
1) get cervus elaphus linnaeus 1kg, be ground into fine powder, for subsequent use after crossing 80 mesh sieves;
2) get ginseng 2kg, add 8 times amount 70%7 alcohol refluxs and extract 2 times, each 2 hours, filter, merging filtrate, reclaim ethanol and concentrate;
3) get the dregs of a decoction after fruit of Chinese wolfberry 2kg, stem of noble dendrobium 2kg and ginseng alcohol extract, add water 5 times amount soak by water 3 times, each 1 hour, filters, carry concentrate and merge, be condensed into thick paste (density is 1.20 ~ 1.30) with panaxynol;
4) cervus elaphus linnaeus fine powder is admixed thick paste, drying under reduced pressure (60 ~ 80 DEG C), obtains dry extract, is ground into fine powder;
5) " step 4) " dry extract is added appropriate filler and loads Capsules and (or to load after making particle
Capsules), every loading amount is 0.4 ~ 0.5g, namely makes capsule.
Embodiments of the invention 3:
1) get cervus elaphus linnaeus 1kg, be ground into fine powder, for subsequent use after crossing 80 mesh sieves;
2) get ginseng 4kg, add 4 times amount 70% alcohol refluxs and extract 3 times, each 1 hour, filter, merging filtrate, reclaim ethanol and concentrate;
3) get the dregs of a decoction after fruit of Chinese wolfberry 8kg, stem of noble dendrobium 8kg and ginseng alcohol extract, add water 8 times amount soak by water 2 times, each 1 hour, filters, carry concentrate and merge, be condensed into thick paste (density is 1.20 ~ 1.30) with panaxynol;
4) cervus elaphus linnaeus fine powder is admixed thick paste, drying under reduced pressure (60 ~ 80 DEG C), obtains dry extract, is ground into fine powder;
5) get " step 4) " dry extract, add beeswax, soybean wet goods appropriate amount of auxiliary materials, making every loading amount is the soft capsule of 0.4 ~ 0.6g.
Embodiments of the invention 4:
1) get ginseng 4kg, cervus elaphus linnaeus 1kg, add 6 times amount 70% alcohol refluxs and extract 3 times, each 1.5 hours, filter, merging filtrate, reclaim ethanol and concentrate;
2) get the dregs of a decoction after fruit of Chinese wolfberry 4kg, stem of noble dendrobium 4kg and " step 1) " alcohol extract, add 10 times amount soak by water 2 times, each 1.5 hours, filter, merge with rapid " 1 " alcohol extracting concentrate;
3) get liquid after the merging of step " 2 ", add water in right amount and flavor enhancement after filtration, namely make oral liquid.
Embodiments of the invention 5:
1) get ginseng 2kg, cervus elaphus linnaeus 1kg, add 6 times amount 70% alcohol refluxs and extract 3 times, each 1.5 hours, filter, merging filtrate, reclaim ethanol and concentrate;
2) get the dregs of a decoction after fruit of Chinese wolfberry 4kg, stem of noble dendrobium 4kg and " step 1) " alcohol extract, add 5 times amount soak by water 3 times, each 2 hours, filter, merge with rapid " 1 " alcohol extracting concentrate;
3) get liquid after the merging of step " 2 ", add the auxiliary materials such as suitable amount of sucrose, controlling spray gun internal pressure is 1.0 ~ 1.5bar, and outer stressor layer is 2.0 ~ 3.0bar, namely makes granule.
Claims (8)
1. a ginseng and pilose antler stem of noble dendrobium health food, is characterized in that: according to listed as parts by weight, and it is made up of ginseng 1 ~ 5 part, cervus elaphus linnaeus 0.1 ~ 1 part, the fruit of Chinese wolfberry 1 ~ 5 part, the stem of noble dendrobium 1 ~ 5 part.
2. a kind of ginseng and pilose antler stem of noble dendrobium health food according to claim 1, is characterized in that: according to listed as parts by weight, and it is ginseng 2 ~ 4 parts, cervus elaphus linnaeus 0.5 ~ 1 part, the fruit of Chinese wolfberry 2 ~ 4 parts, the stem of noble dendrobium 2 ~ 4 parts are made.
3. a kind of ginseng and pilose antler stem of noble dendrobium health food according to claim 2, it is characterized in that: according to listed as parts by weight, dried cream powder is made through extracting by ginseng 2 ~ 4 parts, cervus elaphus linnaeus 0.5 ~ 1 part, the fruit of Chinese wolfberry 2 ~ 4 parts, the stem of noble dendrobium 2 ~ 4 parts, add excipient or diluent, make tablet or capsule or soft capsule.
4. a kind of ginseng and pilose antler stem of noble dendrobium health food according to claim 2, it is characterized in that: according to listed as parts by weight, making medicinal extract by ginseng 2 ~ 4 parts, cervus elaphus linnaeus 0.5 ~ 1 part, the fruit of Chinese wolfberry 2 ~ 4 parts, the stem of noble dendrobium 2 ~ 4 parts through extracting, adding diluent or flavor enhancement, making granule or oral liquid.
5. a kind of ginseng and pilose antler stem of noble dendrobium health food according to claim 3, is characterized in that preparation method comprises the following steps:
1) get cervus elaphus linnaeus and be ground into fine powder, for subsequent use;
2) get people and participate in 4 ~ 8 times amount alcohol refluxs extraction 2 ~ 3 times, each 1 ~ 2 hour, filter, merging filtrate, reclaim ethanol and concentrate;
3) get the dregs of a decoction after the fruit of Chinese wolfberry, the stem of noble dendrobium and ginseng alcohol extract, add 5 ~ 10 times amount soak by water 2 ~ 3 times, each 1 ~ 2 hour, filter, carry concentrate with panaxynol and merge;
4) by concentration of liquid medicine to the relative density of " step 3) " be the thick paste of 1.20 ~ 1.30 (50 DEG C of surveys), mix with the cervus elaphus linnaeus fine powder of " step 1) ", dry, pulverize after mixing, add appropriate excipient or diluent, make tablet or capsule or soft capsule.
6. a kind of ginseng and pilose antler stem of noble dendrobium health food according to claim 4, is characterized in that preparation method comprises the following steps:
1) get ginseng, cervus elaphus linnaeus adds 4 ~ 8 times amount alcohol refluxs and extract 2 ~ 3 times, each 1 ~ 2 hour, filter, merging filtrate, reclaim ethanol and concentrated;
2) get the dregs of a decoction after the fruit of Chinese wolfberry, the stem of noble dendrobium and " step 1) " alcohol extract, add 5 ~ 10 times amount soak by water 2 ~ 3 times, each 1 ~ 2 hour, filter, merge with step " 1 " alcohol extracting concentrate;
3) get liquid after the merging of " step 2) ", add diluent or flavor enhancement after filtration, make granule or oral liquid.
7. the backflow concentration of alcohol in claim 5 in " step 2) " and claim 6 described in " step 1) " is 70%, and reflow's cycle is 3 times, and after reclaiming ethanol, concentration of liquid medicine is to density 1.10 ~ 1.20 (50 DEG C of surveys).
8. in claim 5 in " step 3) " and claim 6 " step 2) " decocts number of times is 2 times, and each time is 1.5 hours.
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