CN104324273A - Traditional Chinese medicine for treating prostatic hyperplasia - Google Patents
Traditional Chinese medicine for treating prostatic hyperplasia Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine for treating prostatic hyperplasia. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 9 parts of nepeta glechoma benth, 6 parts of fried rhizoma anemarrhenae, 8 parts of fried cortex phellodendri, 8 parts of polygonum cuspidatum, 9 parts of pyrrosia lingua, 9 parts of fringed pink, 10 parts of lalang grass rhizome and 6 parts of sargent gloryvine. Proven by clinical experiments, the traditional Chinese medicine is capable of treating the prostatic hyperplasia safely and effectively.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of hyperplasia of prostate.
Background technology
Definition
Hyperplasia of prostate is also called prostate hyperplasia.Hyperplasia of prostate disease is a kind of commonly encountered diseases of elderly men, and age of onset is mostly after 50 years old, and its sickness rate also constantly raises with age.Its pathological change is mainly prostata tissue and epithelial proliferation, therefore claims hyperplasia of prostate disease.
The cause of disease and pathology
In hyperplasia of prostate and body androgen and estrogenic dysequilibrium in close relations.Testosterone is male's chief androgen, under the effect of 5 alpha-reductases, becomes two hydrogen testosterone.The two hydrogen testosterone of 5 α is the active hormones that androgen stimulates hyperplasia of prostate.It becomes complex with receptors bind in prostatic cell, and is transferred in nucleus, interacts and the differentiation produced cell and growth with chromatin.Carry out the experimental results nearby to show, estrogen also has certain influence to hyperplasia of prostate.In liver blood and prostata tissue, androgen can change estrogen into.Estrogen reduces androgenic generation by suppressing the release of hypophysis luteotropic hormone on the one hand, and estradiol can increase tissue to the absorption of two hydrogen amount testosterone and conversion on the other hand.Estrogen can also increase the combination of androgen and receptor.In recent years, someone proposed hyperplasia of prostate and cholesterol-associated, needed to be inquired into further.
Symptom
Main manifestations is two groups of symptoms, and a class is irritation sign of bladder; Another kind of be because of hypertrophy prostate block urinary tract produce obstructive symptoms.Irritation sign of bladder: frequent micturition, urgent micturition, nocturia increase and urge incontinence.Frequent micturition is the early signal of hyperplasia of prostate, and especially nocturia increased frequency more has clinical meaning.This disease has three principal characters: prostate volume increases; Bladder outlet obstruction; There are the lower urinary tract symptoms such as dysuria, frequent micturition, urgent micturition.
Medical material present Research involved in the present invention is as follows:
Herba Glechomae: [source] this product is the dry aerial parts of labiate HUOXUEDAN Glechoma longituba (Nakai) Kupr..Spring gathered to autumn, and removing impurity, dries.[nature and flavor] pungent, micro-hardship, is slightly cold.[return through] returns liver, kidney, urinary bladder channel.[function cures mainly] dampness removing is treating stranguria, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling.For pyretic stranguria, stranguria caused by urinary stone, jaundice due to damp-heat, sore, carbuncle and painful swelling, injury from falling down.[usage and dosage] 6 ~ 30g; Suitable amount used externally, decocts soup and washes or get fresh goods and mash deposited affected part.
The Rhizoma Anemarrhenae: [source] this product is the dry rhizome of liliaceous plant Rhizoma Anemarrhenae Anemarrhena asphodeloides Bunge..Spring, Qiu Erji excavate, and removing fibrous root and silt, dry, and practise and claim " RHIZOMA ANEMARRHENAE with peet "; Or removing crust, dry.[nature and flavor] are bitter, sweet, cold.[return through] returns lung, stomach, kidney channel.[function cures mainly] clearing away heat-fire, promotes the production of body fluid and moisturizes.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.[usage and dosage] 6 ~ 12g.
Cortex Phellodendri: [source] this product is the dry bark of rutaceae wampee Phellodendron chinense Schneid. or Cortex Phellodendri Phellodendron amurense Rupr..The former practises title " Cortex Phellodendri ", and the latter practises title " Cortex Phellodendri ".After stripping bark, removing rough bark, dries.[nature and flavor] are bitter, cold.[return through] returns kidney, urinary bladder channel.[function cures mainly] heat clearing and damp drying, pathogenic fire purging removes steams, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity { is warded off }, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.[usage and dosage] 3 ~ 12g; Suitable amount used externally.
Rhizoma Polygoni Cuspidati: [source] this product is polygonaceae plant Rhizoma Polygoni Cuspidati Polygonum cuspidatum Sieb. et Zucc., dry rhizome and root.Spring, Qiu Erji excavate, and removing fibrous root, cleans, take advantage of short section of fresh-cut or sheet, dry.[nature and flavor] micro-hardship, is slightly cold.[return through] returns liver, gallbladder, lung meridian.
[function cures mainly] expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea, lump in the abdomen, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus, cough with copious phlegm.[usage and dosage] 6 ~ 15g.Suitable amount used externally, makes decocting liquid or ointment coating.
Folium Pyrrosiae: [source] this product is the dried leaves of Plants of Polypodiaceae pyrrosia sheareriChing Pyrrosia sheareri (Bak.) Ching, Folium Pyrrosiae Pyrrosia lingua (Thunb.) Farwell or pyrrosia petiolosaChing Pyrrosia petiolosa (Christ) Ching.The whole year all can gather, and removing rhizome and root, dry or dry in the shade.[nature and flavor] are sweet, bitter, are slightly cold.[return through] returns lung, urinary bladder channel.[function cures mainly] inducing diuresis for treating stranguria syndrome, clearing away heat to stop bleeding.For pyretic stranguria, stranguria with blood, stranguria caused by urinary stone, urinary obstruction, drenches the puckery pain of drop, spits blood, epistaxis, hematuria, metrorrhagia, dyspnea and cough due to lung-heat.[usage and dosage] 6 ~ 12g.
Herba Dianthi: [source] this product is the dry aerial parts of Caryophyllaceae carnation Herba Dianthi Dianthus superbus L. or Dianthus chinensis Dianthus chinensis L..Summer, season in autumn two flowering fruit bearing stage tap, removing impurity, dry.[nature and flavor] are bitter, cold.[return through] GUIXIN, small intestine meridian.[function cures mainly] inducing diuresis for treating stranguria syndrome, removing blood stasis stimulates the menstrual flow.For pyretic stranguria, stranguria with blood, stranguria caused by urinary stone, urinary obstruction, drenches the puckery pain of drop, menstruation apolipsis.[usage and dosage] 9 ~ 15g.
Rhizoma Imperatae: [source] this product is the dry rhizome of grass Herba Imperatae Imperata cylindrica Beauv. var. major (Nees) C. E. Hubb..Spring, Qiu Erji excavate, and clean, dry, and removing fibrous root and film quality sheath, be bundled into wisp.[nature and flavor] are sweet, cold.[return through] returns lung, stomach, urinary bladder channel.[function cures mainly] cooling blood for hemostasis, clearing away heat and promoting diuresis.Spit blood for heat in blood, epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria; Acute nephritis edema.[usage and dosage] 9 ~ 30g, fresh goods 30 ~ 60g.
Caulis Sargentodoxae: [source] this product is the dry rattan of plants of Lardizabalaceae Caulis Sargentodoxae Sargentodoxa cuneata (Oliv.) Rehd.et Wils..Autumn, season in winter two gather, removing side shoot, and intercept is dry.
[nature and flavor] are bitter, flat.[return through] returns large intestine, Liver Channel.[function cures mainly] heat-clearing and toxic substances removing, invigorates blood circulation, dispels the wind.For abdominalgia with intestinal abscess, amenorrhea dysmenorrhea, rheumatic arthralgia, tumbling and swelling.[usage and dosage] 6 ~ 15g.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of hyperplasia of prostate, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing hyperplasia of prostate.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of hyperplasia of prostate, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Glechomae 9 parts, stir-baked RHIZOMA ANEMARRHENAE 6 parts, Cortex Phellodendri (parched) 8 parts, Rhizoma Polygoni Cuspidati 8 parts, Folium Pyrrosiae 9 parts, Herba Dianthi 9 parts, Rhizoma Imperatae 10 parts, Caulis Sargentodoxae 6 parts.
Inventor thinks that hyperplasia of prostate belongs to the one of stranguria, and because Liver and kidney is deficient, in body, the dredging of water liquid is not smooth, pools in the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, then sends out as hyperplasia of prostate disease therefore assembly we male.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and syndrome similar to wind disease patient 94 example of being in hospital altogether in inventor in June, 2012 ~ 2013 between year February, be divided into treatment group 47 example and matched group 47 example at random, 54 ~ 78 years old age, 65.8 years old mean age, the course of disease 1 ~ 12 year; 53 ~ 74 years old age, 63.9 years old mean age, the course of disease 0.6 ~ 11 year.2 groups of ages and course of disease comparing difference not statistically significant, have comparability.
2, test method
2.1 Therapeutic Method
The decoct that the oral the present invention for the treatment of group obtains according to specific embodiment 1, every day 3 times.January was 1 course for the treatment of.Observe the curative effect after 2 courses for the treatment of.
Matched group is oral: oral Longbishu Jiaonang. (every 0.3g, Kedi Pharmaceutical Co., Ltd., Shijiazhuang produces, authentication code: the accurate word Z10960007 of traditional Chinese medicines) treatment, each 3 every days 2 times.January was 1 course for the treatment of.Observe the curative effect after 2 courses for the treatment of.
3, therapeutic outcome
Criterion of therapeutical effect
L, criterion of therapeutical effect: the related content of closing with reference to " disease of tcm Standardization of diagnosis and curative effect ",
Effective: unobstructed micturition, transference cure, ultrasound diagnosis prostatic hyperplasia obviously reduces before comparatively treating, without residual urine;
Effective: symptom alleviates, ultrasound diagnosis prostatic hyperplasia makes moderate progress before comparatively treating, and residual urine reduces;
Invalid: clinical symptoms is without improvement, and ultrasound diagnosis prostate size is without change.
Therapeutic outcome is in table 1.
Table 1 liang group comparitive study
| Group | Number of cases | Effective | Effectively | Invalid | Total effective rate (%) | Serious adverse reaction number of cases |
| Treatment group | 47 | 29 | 15 | 3 | 93.6% * | 0 |
| Matched group | 47 | 17 | 18 | 12 | 74.5% | 0 |
Compare with matched group,
*p<0.05.
Visible, the medicine that the present invention obtains can safe and effective treatment syndrome similar to wind disease, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Herba Glechomae 9 grams, stir-baked RHIZOMA ANEMARRHENAE 6 grams, Cortex Phellodendri (parched) 8 grams, Rhizoma Polygoni Cuspidati 8 grams, Folium Pyrrosiae 9 grams, Herba Dianthi 9 grams, Rhizoma Imperatae 10 grams, Caulis Sargentodoxae 6 grams; First above eight taste medical materials are added 6 times of water gagings, decoct 1 hour, filter; Filtering residue adds 8 times of water gagings again, decocts 1.5 hours, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of hyperplasia of prostate.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: Herba Glechomae 9 grams, stir-baked RHIZOMA ANEMARRHENAE 6 grams, Cortex Phellodendri (parched) 8 grams, Rhizoma Polygoni Cuspidati 8 grams, Folium Pyrrosiae 9 grams, Herba Dianthi 9 grams, Rhizoma Imperatae 10 grams, Caulis Sargentodoxae 6 grams; Above 8 taste medicines add 6 times of water gagings, decoct 1 hour, filter; Filtering residue adds 10 times of water gagings, decocts 2 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of hyperplasia of prostate.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take: Herba Glechomae 9 grams, stir-baked RHIZOMA ANEMARRHENAE 6 grams, Cortex Phellodendri (parched) 8 grams, Rhizoma Polygoni Cuspidati 8 grams, Folium Pyrrosiae 9 grams, Herba Dianthi 9 grams, Rhizoma Imperatae 10 grams, Caulis Sargentodoxae 6 grams; First above eight taste medical materials are added 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 8 times of water gagings again, decocts 3 times, and each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of hyperplasia of prostate.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. one kind is used for the treatment of the Chinese medicine of hyperplasia of prostate, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Glechomae 9 parts, stir-baked RHIZOMA ANEMARRHENAE 6 parts, Cortex Phellodendri (parched) 8 parts, Rhizoma Polygoni Cuspidati 8 parts, Folium Pyrrosiae 9 parts, Herba Dianthi 9 parts, Rhizoma Imperatae 10 parts, Caulis Sargentodoxae 6 parts.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410683400.7A CN104324273A (en) | 2014-11-25 | 2014-11-25 | Traditional Chinese medicine for treating prostatic hyperplasia |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410683400.7A CN104324273A (en) | 2014-11-25 | 2014-11-25 | Traditional Chinese medicine for treating prostatic hyperplasia |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105396053A (en) * | 2015-11-23 | 2016-03-16 | 徐海宁 | Traditional Chinese medicine composition for treating prostatic hyperplasia |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101099779A (en) * | 2007-07-26 | 2008-01-09 | 陈忠 | Medicine for treating prostatic hyperplasia and preparing method thereof |
| CN102240320A (en) * | 2011-07-04 | 2011-11-16 | 河南中医学院 | Motherwort and astragalus capsule used for treating prostatic hyperplasia |
-
2014
- 2014-11-25 CN CN201410683400.7A patent/CN104324273A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101099779A (en) * | 2007-07-26 | 2008-01-09 | 陈忠 | Medicine for treating prostatic hyperplasia and preparing method thereof |
| CN102240320A (en) * | 2011-07-04 | 2011-11-16 | 河南中医学院 | Motherwort and astragalus capsule used for treating prostatic hyperplasia |
Non-Patent Citations (1)
| Title |
|---|
| 王道俊等: ""通关大黄牡丹汤"治疗慢性前列腺炎80例临床观察", 《江苏中医药》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105396053A (en) * | 2015-11-23 | 2016-03-16 | 徐海宁 | Traditional Chinese medicine composition for treating prostatic hyperplasia |
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Application publication date: 20150204 |