CN104323280A

CN104323280A - Total nutrient formula food for treating prostatic cancer

Info

Publication number: CN104323280A
Application number: CN201410575380.1A
Authority: CN
Inventors: 胡安然
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-10-25
Filing date: 2014-10-25
Publication date: 2015-02-04

Abstract

The invention provides total nutrient formula food, specific total nutrient formula food or non-total nutrient formula food for treating prostatic cancer patients. The food is obtained by crushing and mixing multiple medicinal and edible Chinese medicinal extract essences extracted by adopting a pre-hydrolytic SBE (Starch Branching Enzyme) technology, multiple microencapsulated probiotics, short peptides extracted by adopting biological enzymolysis, prebiotics, amino acids, carbohydrates, multiple vitamins and minerals according to the requirements of General Rules of Formula Food with Special Medical Uses in combination with the physical characteristics of prostatic cancer patients. The formula food can serve as a single nutrient source to meet the nutrient requirements of the prostatic cancer patients, and also achieves the effects of clearing heat and promoting diuresis, nourishing yin to lessen fire, resolving toxin and removing stasis, invigorating qi and blood, eliminating sputum and softening hard mass, nourishing yin and yang and enhancing immunity.

Description

The full nutritional formulas of prostate cancer

Technical field

The invention belongs to integration of drinking and medicinal herbs class formula and food technology field, specifically the Traditional Chinese Medicine marrow of " Chinese medicine of integration of drinking and medicinal herbs " is theoretical and " multiple probio " combines, and adds the full nutritional formulas of prostate cancer, specific full nutritional formulas or the non-fully nutritional formulas made for auxiliary material with small peptide, prebiotics, amino acid, carbohydrate, B B-complex, composite mineral matter.

Background technology

Prostate cancer (another name: tumor of prostate is English: Prostate cancer) refer to and occur in prostatic epithelial malignancy, it is the result of prostatic acini cellular abnormality random growth, prostate cancer is apt to occur in 60 ~ 80 years old male patient, less than 40 years old rare, the incidence of disease of prostate cancer has significantly geographical and racial difference, its incidence of disease countries in the world are very inconsistent, the American-European incidence of disease is higher than area, Asia and Africa, the incidence of disease of the U.S. is 14.3 ~ 23,/10 ten thousand male sex, the incidence of disease of China is 0.482/10 ten thousand male sex, but in recent years in rapid ascendant trend, the early stage non-evident sympton of patients with prostate cancer, be everlasting health check-up time chance on, along with tumour development, prostate cancer will there will be multiple different symptoms, prostate cancer is the recurrent a kind of disease of the male sex, the death rate that this disease causes clinically is also very high, a lot of man is made to feel panic, the definite cause of disease of prostate cancer is still not clear so far, a lot of people expresses possibility relevant to the change of gene, change as androgen receptor related gene can cause the risk of prostate cancer to increase, the change of gene also may be relevant to environmental factors such as diet, gene alteration is more, the danger of suffering from prostate cancer is larger, prostate cancer may have heredity in limited instances, in the investigation of that medical circle, the pathogenic factor of most possible prostate cancer ,1. absolute hazards: (1) age: the age is the main hazards of prostate cancer, prostate cancer is very rare in the male sex being less than 45 years old, but along with the increase at age, the incidence of disease of prostate cancer sharply raises, the age of most patients with prostate cancer is greater than 65 years old, substantially, after 40 years old, the age often increases by 10 years old, the incidence of disease of prostate cancer just almost doubles, it is 10% that 50 ~ 59 years old male sex suffer from the danger of prostate cancer, and the danger that 80 ~ 89 years old male sex suffers from prostate cancer increases to 70% suddenly, (2) family history: when there being lineal remote kinsman to suffer from prostate cancer in family, in this family, male sex's incidence of disease obviously increases, lineal remote kinsman refers generally to father and brother, if there is 1 lineal relative to suffer from prostate cancer in relatives, the probability of so suffering from prostate cancer will be higher than general population 1 times, if there are 2, will be high 3 times, this show prostate cancer generation may with in body or one group of gene-correlation, just up to the present these genes also are not identified out by scientist completely, (3) ethnic group: the incidence of disease of prostate cancer in African American (i.e. U.S. black race) is the highest, next is Spaniard and American caucasian, and the incidence of African black race's prostate cancer is minimum in world wide, live in the incidence of asian ancestry's prostate cancer of the U.S. lower than white people, but apparently higher than the native country male sex in Asia, although the incidence of disease of prostate cancer in yellow does not also reach the level of American-European countries, but no matter be China's Mainland, TaiWan, China, Hong Kong, or Japan, Korea S, Singapore, the incidence of disease of prostate cancer all presents the trend raised year by year, (4) there is the pathological change of cellular abnormality in prostate: the male sex suffering from prostate intraepithelial neoplasia, the incidence of its prostate cancer obviously raises, intraepithelial neoplasia is a kind of precancerous lesion, it presents the exception of Growth of Cells form under the microscope, though do not belong to cancer, but often point out the existence of prostate cancer, just not yet detect, 2. relative risk factor: (1) diet: some study display, often the edible male sex containing high animal tallow food is also an easily crowd of prostate cancer, because containing more saturated fatty acid in these foods, find from 32 national results of study, the prostate cancer death rate is relevant with total fat intake, and the people's P being rich in vegetables and fruit at ordinary times in diet is lower, (2) androgen levels: in body, androgen levels height is also one of possible inducement of prostate cancer, androgen can promote the growth of prostate cancer, the increase of Chinese residents prostate cancer illness rate and aging population, living standard improves, dietary structure change and environmental pollution relevant, result of study shows: smoking, drink, divorce or the death of one's spouse, and often drink milk, eat eggs and pork is the Major Risk Factors that Chinese suffer from prostate cancer more, and eat dark green vegetables, fruit and bean food are then important protection factors,

Prostate cancer adopts the mode of parenteral nutrition (namely inputting nutritional drugs) to carry out nutritional supplementation to cancer patient clinically more, and long-term parenteral nutrition supplements and easily causes enteron aisle Villus atrophy, and accompanying infection, thus increases the weight of the harm to body; " integration of drinking and medicinal herbs " is to one of contribution of mankind's most worthy among Chinese original medical science; The traditional Chinese medical science is always emphasized " medication not as dietotherapy ", dietotherapy become modern pursue recover one's original simplicity, the optimal selection of health diet; Allow people dispel slight illness in the process enjoying cuisines, avoid and have an injection, take medicine, even pain of surgery.

For food of special nutrients, there are corresponding regulation and Application and Development in the developed country such as the U.S., European Union; And the full nutritional formulas of wholefood clear stipulaties: 2.1.1 in China GB29922-2013 " special medicine purposes formula food general rule " national food safety standard: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need; 2.1.2 specific full nutritional formulas: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need under specified disease or medical condition.

Traditional Chinese medical science traditional medicine is thought: " spleen (i.e. digestive system) is the foundation of acquired constitution ", and stomach health is healthy basis, and 99% of human nutrition needs by intestinal absorption, and intestinal bowel disease is also the source of ten thousand diseases; But along with the age is larger, in enteron aisle, profitable strain (probio) ratio reduces gradually; As Bifidobacterium Bifidum accounts for 98% infant period, be down to 10% to during the middle age, within 65 years old, only account for 5% later; People is older, and probio is fewer, and function of intestinal canal also declines thereupon gradually, more and more studies display, normal flora human consumption, immunity and disease-resistant etc. in have many irreplaceable effects; The change of gut flora composition and the generation of various diseases, particularly intestines problem develop closely related, and find from existing clinical research: probio can play regulating intestinal canal flora, controls intestinal inflammatory effect, is that one intervenes control method safely and effectively.

Though direct probiotic oral has certain effect, but due to probio one cannot field planting in enteron aisle, and stop, occupy-place is little, easily run off, withdraw rear harmful bacteria and easily recur, associated patient needs long-term taking, and treatment cycle is long, often uses afterwards that recurrence rate is very high, for shortening the treatment cycle of associated patient, recurrence rate after minimizing drug withdrawal, this team is by studying the key technology of probio field planting mechanism in enteron aisle over nearly 3 year, make great efforts " Chinese medicine of the integration of drinking and medicinal herbs " compound seeking to improve probio field planting in enteron aisle, consider several key elements of probio field planting in enteron aisle: the existence of prebiotics can play field planting effect, the reduction of intestinal pH environment and the enteron aisle adhesive capacity etc. of raising probiotic cell, based on above-mentioned key element, suitable food materials screen from tens of kinds " Chinese medicines of integration of drinking and medicinal herbs " in this seminar, Late Cambrian interpolation Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, the extract of the traditional Chinese medicine ingredients of the integration of drinking and medicinal herbs such as Gorgon fruit and jerusalem artichoke and stachyose, yeast, after Glu etc., very strong field planting effect is had to external source probio, prescription for probio in enteral microecological formulation is selected to provide experimental basis.

Favourable is in the market primary raw material in order to eat source property small peptide, add the mushroom of medicine-food two-purpose, dried orange peel, matrimony vine, Chinese yam, Poria cocos, the extract of sealwort etc., B B-complex and mineral matter composition compound prescription, utilize the product that probio is primary raw material in addition, but also do not find the constitutive character in conjunction with patients with prostate cancer, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility is with the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials is the full nutritional formulas that auxiliary material is made, specific full nutritional formulas or similar products.

goal of the invention

The object of the invention is on the theoretical treatment method of succession traditional Chinese medical science marrow, the initiative extract by the probio of multiple raising patients with prostate cancer immunity and " Chinese medicine of integration of drinking and medicinal herbs " compound combines, add with small peptide, amino acid, carbohydrate, multivitamin, several mineral materials is auxiliary material, the patients with prostate cancer institute essential nutrients of hypoimmunity can not only be supplemented, improve body nutrition condition, can also and utilize function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function, probio can play regulating intestinal canal flora, toxic and side effect is little, safe and effective, and the full nutritional formulas that the acceptable applicable patients with prostate cancer of people is edible, specific full nutritional formulas or non-fully nutritional formulas.

summary of the invention:

This R&D team is according to the requirement of " special medicine purposes formula food general rule ", the constitutive character of the patients with prostate cancer that binding immunoassay power is low, the advanced physiology of comprehensive nowadays American Harvard University, medicine, the achievement in research such as nutrition and clinical practice, according to " the middle residence that disappears benefit ", marrow theory (the liver of the Traditional Chinese Medicine of " equilibrium is taken good care of ", spleen, kidney three is dirty with being adjusted to main principle), adopt the Chinese medical extract elite of more than 4 kinds medicine-food two-purposes, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin and mineral matter auxiliary material, not only can be used as the nutritional need that single source of nutrition meets patients with prostate cancer, also has clearing heat and promoting diuresis, nourishing Yin and falling fire, detoxicating and resolving a mass, tonifying Qi and blood, resolving phlegm and softening hard masses, the full nutritional formulas of effect of nourishing YIN for harmonizing YANG and develop immunitypty, specific full nutritional formulas or non-fully nutritional formulas (compound prescription be combined into).

1, the main component of the present invention's formula is:

Chinese medical extract is dirty with being adjusted to main principle from the liver,spleen,kidney three theory of traditional Chinese medical science according to the constitutive character of patients with prostate cancer, utilize the function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function to build up resistance, and choose following several large class medicine and carry out compatibility; Wherein: the stem of noble dendrobium, reinforcing stomach reg fluid is nourishing Yin and clearing heat; Plantain seed, promoting diuresis for stranguria, excreting dampness antidiarrheal, clear liver and improve vision, clearing heat and eliminating phlegm; Semen allii tuberosi, warm filling liver kidney, establishing-Yang controlling nocturnal emission with astringent drugs, warm waist knee; The bighead atractylodes rhizome, has strengthening the spleen and replenishing qi, eliminating dampness Li Shui, hidroschesis, antiabortive effect; Black nightshade, eliminating stasis to subdue swelling is clearing heat and detoxicating; The fruit of glossy privet, tonifying liver kidney yin; Cordyceps militaris, Chinese caterpillar fungus enters lung kidney two warp, can tonifying lung cloudy, again can kidney-replenishing, cure mainly and suffer from a deficiency of the kidney, impotence and seminal emission, soreness of waist and knee joint, weak after being ill, chronic cough is weak, phthisical cough phlegm blood, and spontaneous sweating etc. are unique a kind of Chinese medicine that can balance simultaneously, regulate negative and positive; Pumpkin seeds, nature and flavor are put down, and taste is sweet, cures mainly expelling parasite, detumescence; Bee Pollen, strengthens human body comprehensive immunologic function: pollen polysaccharide energy activating macrophage engulf activity, improve human disease resistance; Poria cocos, has clearing damp and promoting diuresis, invigorating the spleen, the effect of calming the nerves; Coix seed, energy invigorating spleen and reinforcing stomach, the dehumidifying of the profit moon, relaxes contraction, clearing lung-heat heat; Rde bean, energy inducing diuresis and reducing edema, heat-clearing removing jaundice, detoxify and drain pus; Gorgon fruit, reinforcing the kidney and controlling noctural emission, tonifying spleen stopping leak, clearing damp and promoting diuresis; Chinese yam, tonifying spleen nourishing the stomach, promote the production of body fluid beneficial lung, the puckery essence of kidney tonifying; Matrimony vine, the immunity of nourishing liver and kidney, benefiting shrewd head and the people that nourish blood, strengthen; Ginseng, tonifying Qi, Gu de-, promote the production of body fluid, calms the nerves, intelligence development;

Medicinal and edible Chinese medicine extract of the present invention refers to Cordyceps sinensis (aweto mycelium), the stem of noble dendrobium, lucidum spore powder (broken wall), glossy ganoderma, plantain seed, lycopene, semen allii tuberosi, the bighead atractylodes rhizome, black nightshade, the fruit of glossy privet, tortoiseshell, Cordyceps militaris, pumpkin seeds, Bee Pollen (broken wall: rape pollen, Pollen Astragali Melilotoidis (Pollen Astragali Sinici), sesame pollen), Poria cocos, coix seed, rde bean, Gorgon fruit, Chinese yam, matrimony vine, ginseng, walnut kernel, marine alga, kelp, Chinese cassia tree, date, water caltrop starch, dandelion, cordate houttuynia, purslane, mulberry fruit wherein more than 4 kinds or all, biological enzymolysis or prehydrolysis SBE is adopted to extract and microencapsulation, mixture after spray-dried and cryodesiccated extract.

2, multiple probio: make probio major part can arrive enteron aisle by the strong acid environment of stomach, to promote the propagation of probio, regulate microecological balance in intestines, promote the absorption to trace element, strengthen taste motor function, accelerate the absorption of drug effect, improve the micropopulation of mucous membrane surface or the balance of enzyme, or stimulate body specificity or nonspecific immunity mechanism, improve body colonization resistance or immunity; Xing etc., with Bifidobacterium and Bacillus acidi lactici pretreatment law during ischemia/reperfusion rat, obviously can reduce the level of intestinal endotoxemia and the generation of preventing liver injury; Selective enteron aisle decontamination dye is also the important measures of adjustment intestinal microecology, has research application enteron aisle not absorb rifamycin antibiotic former times bright (rifaximin), by urease-producing in suppression enteron aisle and the growth of producing ammonium bacteria, builds up resistance;

Multiple probio of the present invention all adopts the probio after microencapsulation, except streptococcus thermophilus, wherein Bifidobacterium: refer to that bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum are wherein a kind of, several or all mix; Lactobacillus refers to: lactobacillus acidophilus powder, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, Lactobacillus plantarum, lactobacillus paraceasi, Yue Shi lactobacillus are wherein a kind of, several or all mix.

3, small peptide: be oligopeptide, refer to the small molecule protein utilizing bio-enzyme engineering technology separation and Extraction from animal or vegetable protein, its mean molecule quantity is at below 1000Dalton, soluble in water, to acid, thermally-stabilised, can not need directly to absorb through digestion, bioavailability is high, absorbing and utilizing the amino acid and complete protein that are better than dissociating, can be applicable in Protein intake food, especially for the crowd that abilities of digestive and absorption is low, small peptide is splendid nitrogenous source, except trophic function, small peptide also has a series of physiological active functions: the digestion and absorption function improving small intestine, strengthen immunity of organisms, anti-oxidant, auxiliary adjustment blood sugar, auxiliary adjustment of blood fat, aided blood pressure-lowering, radioresistance, promote mineral absorption, strengthen the action effect of function factor in medicine-food two-purpose Chinese herbal medicine,

Small peptide of the present invention refers to that maize oligopeptide, wheat oligopeptide, marine collagen peptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide are wherein a kind of, several or all mix.

4, prebiotics: with short probio intestinal colonisation, enteron aisle convergence, reduce intestinal pH environment, also do not utilized by most enteron aisle spoilage organisms, but beneficial bacteria in human body can be promoted---the growth and breeding of lactobacillus, Bifidobacterium, thus spoilage organisms can be suppressed to grow, contribute to improving and maintaining enteron aisle normal function; Long-term edible can to delay senility, defaecation, raising immunity, the absorptivity that alleviates burden of liver, improve nutrient, particularly can improve the absorption of body to metal ions such as calcium, iron, zinc; Optionally promote outside the growth and breeding of beneficial bacterium (bifid, lactic acid), also can metabolism be acid product as organic acids such as lactic acid, knot intestinal pH is reduced, suppresses the growth of intestinal harmful bacillus; Water-Electrolyte in small intestine is made to be trapped in enteric cavity, produce and highly ooze effect, enterocinesia is stimulated to cause laxative, thus promote the discharge of intestinal endotoxin and other toxicants, lactulose also can directly endotoxin in deactivation enteron aisle, reduce gut pH, extensively model is applied to the treatment of enhancing prostate cancer resistance;

Prebiotics of the present invention is 2 classes

A. very strong field planting effect prebiotics is had to external source probio: the extract of Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, jerusalem artichoke, stachyose, yeast wherein several or all mix;

B. common prebiotics: oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix;

Originally oligoisomaltose, stachyose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix is referred to.

5, carbohydrate: carbohydrate is by carbon, hydrogen and oxygen three kinds of element compositions, it is for human body provides nutrient the most cheap in three of heat energy kinds of main nutrients, when taking in sufficient, energy can be provided in time by rapid oxidation in vivo, the protein of preciousness is avoided to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the glycolipid of nerve fiber and the important composition composition of DNA (DNA) conveyed hereditary information, and the glycogen contained in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin that some poisonous chemical substance and various pathogenic microorganisms produce,

Carbohydrate of the present invention refers to Arabinose, fructose, galactolipin, lactose, glucose, maltose, water-soluble dietary fiber, starch, glycogen one wherein, several or all mix.

6. amino acid: be divided into essential amino acid and nonessential amino acid, is the base unit forming protein, gives protein specific molecular morphosis, make it have biochemical activity; Absorb appropriate methionine and contribute to the metabolism of various sulfur-containing compound in human body and the methyl contained by it methylates to Toxic or medicine and plays the effect of removing toxic substances; Leucine can repair muscle, controls blood sugar, and provides energy to bodily tissue, essential amino acid phenylalanine can suppress cancer growth, can reduce again the toxic and side effect of medicine, and lysine can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development; Arginine contributes to changing the ammonia in blood into urea and excreting out; For hyperammonemia, hepatic dysfunction etc. are all powerful; Histidine reduces gastric acidity, relaxes the pain of gastrointestinal procedures, alleviates gestational period vomiting and scorching hot sense, suppresses nervous by vegetative nerve and alimentary canal that is that cause festers, to anaphylactia, as also powerful in asthma etc.; Tryptophan can prevent pellagra, depression, improving water flood and adjustment mood;

Amino acid of the present invention refers to Glu, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix.

7. vitamin and mineral matter:

Vitamin and mineral matter are the nutrients of needed by human, the nutrient of the vitamin added in the present invention to be vitamin and mineral matter be needed by human;

The vitamin added in the present invention is vitamin A, vitamin D, vitamin E, vitamin K, vitamin K1, vitamin C, vitamin B1, vitamin B2, vitamin B6, vitamin B12, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin one wherein, several or all mix;

The mineral matter added in the present invention is calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum one wherein, several or all mix, and mineral matter of the present invention is added to the organic or inorganic compound of this mineral matter;

In the present invention, the addition of vitamin and minerals performs with reference to " special medicine purposes formula food general rule ", now for 1000g finished product, addition is vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g.

8. the present invention is with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology of the industrialization production of formation; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product prevent and treat prostate cancer significantly improves compared with the like product of market.

9. adopt above-mentioned integrated innovation technique various batching to be mixed solid beverage, the granule of making powdery, and be distributed into 10g/ bag, after dissolving with about 150ml warm water (45 degree), directly drink or take in through nasal feeding; Also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require.

The characteristic of this full nutritional formulas of filling a prescription and the following aspects is mainly manifested in the effect of body:

1. the present invention is the requirement according to " special medicine purposes formula food general rule ", in conjunction with the constitutive character of patients with prostate cancer, the achievement in research developments such as the advanced physiology of comprehensive nowadays American Harvard University, medicine, nutrition and clinical practice, vary with each individual, gold compatibility.

2. the present invention is according to the marrow theory (liver,spleen,kidney three is dirty with being adjusted to main principle) of the Traditional Chinese Medicine of " the middle residence that disappears is mended ", " equilibrium is taken good care of ", the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is adopted to be primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin and mineral matter for auxiliary material, the organic assembling of various batching, various function is merged, and by the synergy between active ingredient, humidification effect.

3. have effective absorbency, utilize formula of the present invention, various component adopts the food of suitable ratio collocation preparation, in isotonic state after a certain amount of water-soluble solution, small intestine can be arrived quickly through stomach, absorb fast, completely, patients with prostate cancer desired nutritional can be supplemented rapidly.

4. in the present invention's formula, adopt the extract of various medicine-food two-purpose Chinese herbal medicine, containing several functions active component, not only increase the concentration of function factor, reduce the absorption of various impurity, contribute to alleviating liver kidney burden, have and strengthen the effect of resistance of human body, also have effect of clearing heat and promoting diuresis, nourishing Yin and falling fire, detoxicating and resolving a mass, tonifying Qi and blood, resolving phlegm and softening hard masses, nourishing YIN for harmonizing YANG and develop immunitypty.

5. probio contained in the present invention's formula, multiple probio can safeguard enteron aisle normal bacteria colony balance, suppress the growth of pathogen, prevent gastrointestinal disorders etc., synthetic vitamin in enteron aisle, amino acid and raising body are to the absorption of calcium ion, strengthen human immunologic function, prevent antibiotic side effect, improve host to the tolerance of radioactive ray, lactobacillus significantly increases intestinal mucosal immune globulin A (SIgA) content, to body intestinal mucosa local immunity, there is regulating action, regulate stomach, intestines Tiny ecosystem, calcium can be improved, phosphorus, the utilization rate of iron, promote the absorption of iron and vitamin D, produce vitamin K and Cobastab, the absorption of cholesterol can also be reduced.

6. formula food of the present invention with the food source property bioactive short peptide in multiple source for nitrogenous source, because small peptide does not need digestion and Absorbable rod, more be conducive to the utilization of body, can effectively improve patients with prostate cancer negative nitrogen balance, and food source property small peptide can improve the 26S Proteasome Structure and Function of intestinal epithelial cell, improves the absorbability of intestinal mucosa.

7. this prescription have employed this team by over nearly 3 year to the achievement that the key technology of probio field planting mechanism in enteron aisle is studied, improve " Chinese medicine of integration of drinking and medicinal herbs " compound of probio field planting in enteron aisle, the existence combining prebiotics can play the key elements such as field planting effect, the reduction of intestinal pH environment and the enteron aisle adhesive capacity of raising probiotic cell, and therefore the composition of this food formula greatly strengthen the field planting effect to external source probio.

8. prebiotics contained in the present invention's formula; by promoting the growth and breeding of probio in intestines; suppress the growth of spoilage organisms; form one protective barrier at intestinal mucosal surface simultaneously; the damage of enteron aisle spoilage organisms to intestinal mucosa can be resisted; reduce the absorption of intestinal toxic material; intestines peristalsis can also be promoted; accelerate the discharge of residuals in intestines; constipation can be prevented; and by promoting that the growth and breeding of beneficial bacteria of intestinal tract also can strengthen immunity of organisms, the bioactivators such as small peptide, carbohydrate and active polysaccharide have synergy.

9, in the present invention's formula, contained carbohydrate is for human body provides three of heat energy kinds of main nutrients, energy can be provided in time by rapid oxidation in vivo, the protein of preciousness is avoided to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the glycolipid of nerve fiber and the important composition composition of DNA (DNA) conveyed hereditary information, and the glycogen contained in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin that some poisonous chemical substance and various pathogenic microorganisms produce.

10, contained in the present invention's formula amino acid, it is the base unit forming protein, give protein specific molecular morphosis, make it have biochemical activity, contribute to the metabolism of various sulfur-containing compound in human body and the methyl contained by it methylates to Toxic or medicine and plays the effect of removing toxic substances, muscle can be repaired, control blood sugar, and provide energy to bodily tissue, also can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development.

11, formula food of the present invention is containing multivitamin and mineral matter, can supplement rapidly the micronutrient needed for patients with prostate cancer, small peptide by with the chelating of calcium, iron, zinc etc. after, further increase the absorptivity of mineral matter element.

12, not fatty and cholesterol in the present invention's formula, while supplementary protein, micronutrient, can not increase the absorption of fat, cholesterol, avoid the adverse effect of the high protein diet such as meat, egg.

Detailed description of the invention

Below by following examples, the invention will be further described, and it will contribute to understanding the present invention.

Embodiment one

Realizing the full nutritional formulas of the object of the invention prostate cancer is constitutive character in conjunction with patients with prostate cancer, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with the Chinese medical extract elite of more than 4 kinds medicine-food two-purposes, multiple probio, small peptide for primary raw material, the food made for auxiliary material with prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials;

Fill a prescription by following raw materials according and consumption thereof: the extract of medicine-food two-purpose: Cordyceps sinensis (aweto mycelium) 10g, stem of noble dendrobium 10g, lucidum spore powder (broken wall) 10g, glossy ganoderma 10g, plantain seed 10g, lycopene 10g, semen allii tuberosi 10g, bighead atractylodes rhizome 8g, black nightshade 8g, fruit of glossy privet 8g, tortoiseshell 8g, Cordyceps militaris 8g, pumpkin seeds 8g, Bee Pollen (broken wall: rape pollen, Pollen Astragali Melilotoidis (Pollen Astragali Sinici), sesame pollen) 8g, Poria cocos 6g, coix seed 6g, rde bean 6g, Gorgon fruit 6g, Chinese yam 6g, matrimony vine 6g, ginseng 6g, walnut kernel 4g, marine alga 4g, kelp 4g, Chinese cassia tree 4g, date 4g, water caltrop starch 4g, dandelion 2g, cordate houttuynia 2g, purslane 2g, mulberry fruit 2g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,

During making first will be glossy ganoderma, plantain seed, semen allii tuberosi, the bighead atractylodes rhizome, black nightshade, the fruit of glossy privet, tortoiseshell, pumpkin seeds, rde bean, matrimony vine, ginseng, walnut kernel, marine alga, kelp, Chinese cassia tree, date, dandelion, cordate houttuynia, purslane, mulberry fruit, the membrane of a chicken's gizzard, Chinese yam, Gorgon fruit soak after add cycloheptaamylose, after extracting by prehydrolysis SBE technology, spray-dried and preparation flour, then add biological enzymolysis extract small peptide, prebiotics, amino acid, Cordyceps sinensis (aweto mycelium), the stem of noble dendrobium, lucidum spore powder (broken wall) ,carbohydrate, Cordyceps militaris, multivitamin and mineral matter, and add lycopene, Bee Pollen (broken wall: rape pollen, Pollen Astragali Melilotoidis (Pollen Astragali Sinici), sesame pollen), Poria cocos, coix seed, water caltrop starch carry out pasteurization 1 hour after being pulverized and mixed together, then the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus mix solid beverage, the granule of making powdery is added, and be distributed into 10g/ bag, after dissolving by about 150ml warm water (45 degree), directly drink or take in through nasal feeding; Also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require.

Embodiment two

The full nutritional formulas of above-mentioned prostate cancer also comprises following component by weight: the extract of medicine-food two-purpose: Cordyceps militaris 14g, pumpkin seeds 14g, Bee Pollen (broken wall: rape pollen, Pollen Astragali Melilotoidis (Pollen Astragali Sinici), sesame pollen) 14g, Poria cocos 14g, coix seed 12g, rde bean 12g, Gorgon fruit 12g, Chinese yam 10g, matrimony vine 10g, ginseng 10g, walnut kernel 10g, marine alga 10g, kelp 8g, Chinese cassia tree 8g, date 8g, water caltrop starch 8g, dandelion 6g, cordate houttuynia 6g, purslane 6g, mulberry fruit 6g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g.

Embodiment three

The full nutritional formulas of above-mentioned prostate cancer also comprises following component by weight: the extract of medicine-food two-purpose: Cordyceps militaris 14g, pumpkin seeds 14g, Bee Pollen (broken wall: rape pollen, Pollen Astragali Melilotoidis (Pollen Astragali Sinici), sesame pollen) 14g, Poria cocos 14g, coix seed 12g, rde bean 12g, Gorgon fruit 12g, Chinese yam 10g, matrimony vine 10g, ginseng 10g, walnut kernel 10g, marine alga 10g, kelp 8g, Chinese cassia tree 8g, date 8g, water caltrop starch 8g, dandelion 6g, cordate houttuynia 6g, purslane 6g, mulberry fruit 6g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, carbohydrate 150g, prebiotics 100g, several amino acids 100g.

Embodiment four

The full nutritional formulas of above-mentioned prostate cancer also comprises following component by weight: small peptide 350g, carbohydrate 300g, several amino acids 100g, Bifidobacterium 50g, lactobacillus 50g, streptococcus thermophilus 25g, prebiotics 100g, B B-complex and mineral matter 25g; Energy contained by every 100 g should be not less than 295 kJ (70 kcal).

The present invention with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product improve patients with prostate cancer immunity significantly improves compared with the like product of market.

Claims

1. the full nutritional formulas of prostate cancer, it is characterized in that the constitutive character in conjunction with patients with prostate cancer, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with the Chinese medical extract elite of more than 4 kinds medicine-food two-purposes, multiple probio, small peptide for primary raw material, the food made for auxiliary material with prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials;

Its preparation method is first will to be glossy ganoderma, plantain seed, semen allii tuberosi, the bighead atractylodes rhizome, black nightshade, the fruit of glossy privet, tortoiseshell, pumpkin seeds, rde bean, matrimony vine, ginseng, marine alga, kelp, Chinese cassia tree, date, dandelion, cordate houttuynia, purslane, mulberry fruit, the membrane of a chicken's gizzard, Chinese yam, Gorgon fruit soak after add cycloheptaamylose, with prehydrolysis SBE technology extract after, spray-dried and preparation flour, then add biological enzymolysis extract small peptide, prebiotics, amino acid, Cordyceps sinensis (aweto mycelium), the stem of noble dendrobium, lucidum spore powder (broken wall), carbohydrate, Cordyceps militaris, multivitamin and mineral matter, and add lycopene, Bee Pollen (broken wall: rape pollen, Pollen Astragali Melilotoidis (Pollen Astragali Sinici), sesame pollen), Poria cocos, walnut kernel, coix seed, carry out pasteurization after water caltrop starch is pulverized and mixed together 1 hour, then add the Bifidobacterium after microencapsulation, lactobacillus, the various batchings that streptococcus thermophilus also adds appropriate carbohydrate mixing again mix the solid beverage making powdery, granule, and be distributed into 10g/ bag, after dissolving with about 150ml warm water (45 degree), directly drink or take in through nasal feeding, also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require.

2. the full nutritional formulas formula of prostate cancer according to claim 1, it is characterized in that described medicine-food two-purpose Chinese herbal medicine extract is: Cordyceps sinensis (aweto mycelium), the stem of noble dendrobium, lucidum spore powder (broken wall), glossy ganoderma, plantain seed, lycopene, semen allii tuberosi, the bighead atractylodes rhizome, black nightshade, the fruit of glossy privet, tortoiseshell, Cordyceps militaris, pumpkin seeds, Bee Pollen (broken wall: rape pollen, Pollen Astragali Melilotoidis (Pollen Astragali Sinici), sesame pollen), Poria cocos, coix seed, rde bean, Gorgon fruit, Chinese yam, matrimony vine, ginseng, walnut kernel, marine alga, kelp, Chinese cassia tree, date, water caltrop starch, dandelion, cordate houttuynia, purslane, mulberry fruit wherein more than 4 kinds or all mix.

3. the full nutritional formulas formula of prostate cancer according to claim 1, is characterised in that and can be prepared into powdery, graininess, capsule shape, tablet shape, beverage based food according to described formula mixing.

4. the full nutritional formulas formula of prostate cancer according to claim 1, also comprises following component by weight: small peptide 350g, carbohydrate 300g, several amino acids 100g, Bifidobacterium 50g, lactobacillus 50g, streptococcus thermophilus 25g, prebiotics 100g, B B-complex and mineral matter 25g.

5. the full nutritional formulas formula of prostate cancer according to claim 1, is characterized in that described prebiotics is. have that very strong field planting effect prebiotics is Chinese yam to external source probio, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, the extract of jerusalem artichoke, stachyose, yeast and common prebiotics wherein several or all mix.

6. require the full nutritional formulas formula of the prostate cancer described in 1, it is characterized in that described amino acid is Glu, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix.

7. the full nutritional formulas formula of prostate cancer according to claim 1, is characterized in that described carbohydrate is Arabinose, fructose, galactolipin, lactose, glucose, maltose, water-soluble dietary fiber, starch, glycogen one wherein, several or all mix.

8. the full nutritional formulas formula of prostate cancer according to claim 1, is characterized in that with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology of the industrialization production of formation; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, make product prevent and treat prostate cancer effect and significantly improve compared with the like product of market.

9. the full nutritional formulas formula of prostate cancer according to claim 1, is characterized in that described vitamin is vitamin A, vitamin D, vitamin E, vitamin K, vitamin K1, vitamin C, vitamin B1, vitamin B2, vitamin B6, vitamin B12, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin one wherein, several or all mix; Described mineral matter is calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum one wherein, several or all mix.

10. the full nutritional formulas formula of prostate cancer according to claim 1, is characterized in that described small peptide is marine collagen peptide, maize oligopeptide, wheat oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide is wherein a kind of, several or all mix.