CN104306852A - Preparation method of medicinal liquor for treating rheumatic arthritis - Google Patents
Preparation method of medicinal liquor for treating rheumatic arthritis Download PDFInfo
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- CN104306852A CN104306852A CN201410549736.4A CN201410549736A CN104306852A CN 104306852 A CN104306852 A CN 104306852A CN 201410549736 A CN201410549736 A CN 201410549736A CN 104306852 A CN104306852 A CN 104306852A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9062—Alpinia, e.g. red ginger or galangal
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/04—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Abstract
The invention relates to a preparation method of medicinal liquor for treating rheumatic arthritis. The preparation method comprises the steps of firstly crushing prepared kusnezoff monkshood root and rhizoma galangae, steaming, uniformly mixing the crushed powder with black millet after being cooled and soaked, adding distiller yeast and water at a certain mol ratio, and fermenting the mixture in a ceramic vessel; adding water into the fermented substance, and ultrasonically processing and filtering the fermented substance to obtain a medicinal solution A; crushing angelica sinensis and clove, then adding and uniformly mixing bacillus natto and aquae sterilisata, and fermenting the mixture in the ceramic vessel; adding white spirit in a fermented product, heating the mixture to 50 to 60 DEG C to be thermally preserved after being soaked in white spirit, cooling and filtering the mixed solution to obtain a medicinal solution B; mixing the medicinal solution A and the medicinal solution B to obtain a medicinal solution C; and adding brown granulated sugar which is fried to be toast tan in an iron pot into the medicinal solution C, stirring until the brown granulated sugar is completely dissolved, and filtering the mixed solution to obtain the medicinal liquor for treating protrusion of lumbar intervertebral disc. The medicinal liquor can clear away the internal heat and toxic substances, diminish the swelling, kill the pain, activate the blood, eliminate the stasis and can solve the inflammation surrounding the joint; the immunity function can be adjusted; and the treatment effect on the rheumatic arthritis is good.
Description
Technical field
The present invention relates to a kind of medicated wine, specifically a kind of preparation method for the treatment of the medicated wine of rheumatic arthritis.
Background technology
Rheumatic arthritis belongs to allergic disease, it is one of main manifestations of rheumatic fever, mainly with febris acuta and arthralgia onset, typical performance is slight or moderate heating, migratory polyarthritis, affected joints mostly is knee joint, ankle, shoulder, elbow, the large joint such as wrist, commonly be transferred to another joint by a joint, pathological changes local presents red, swollen, scorching hot, severe pain, some patients also has several joint to fall ill simultaneously, atypical patient only has arthralgia and shows without other inflammation, acute inflammation generally disappears in 2-4 week, do not stay sequela, but normal recurrent exerbation.If active rheumatism affects heart, then can there is myocarditis, even leave over valve disorder.Rheumatic arthritis onset is comparatively anxious, and affected joints, based on large joint, starts to invade and joint of the lower extremity person accounts for 85%, knee joint and ankle joint are the most common, are secondly shoulder, elbow and wrist, the Minor articulus of hands and foot is rare, arthropathy is multiple and migrans, and local joint inflammation is obvious, and performance has red, swollen, heat, bitterly, tenderness and limitation of activity.
Rheumatic arthritis belongs to allergic disease, it is one of main manifestations of rheumatic fever, mainly with febris acuta and arthralgia onset, typical performance is slight or moderate heating, migratory polyarthritis, affected joints mostly is knee joint, ankle, shoulder, elbow, the large joint such as wrist, commonly be transferred to another joint by a joint, pathological changes local presents red, swollen, scorching hot, severe pain, some patients also has several joint to fall ill simultaneously, atypical patient only has arthralgia and shows without other inflammation, acute inflammation generally disappears in 2-4 week, do not stay sequela, but normal recurrent exerbation, if active rheumatism affects heart, then myocarditis can be there is, even leave over valve disorder.
Summary of the invention
The present invention seeks to the deficiency for solving the problems of the technologies described above, providing a kind of preparation method for the treatment of the medicated wine of rheumatic arthritis, prepared medicated wine, can dispel the wind, dehumidify, dispersing cold for relieving pain, for the treatment of rheumatic arthritis.
Treat a preparation method for the medicated wine of rheumatic arthritis, comprise the following steps:
Step one, get Radix Aconiti Kusnezoffii Preparata 20-25 part, Radix Angelicae Sinensis 8-10 part, Flos Caryophylli 8-10 part, Rhizoma Alpiniae Officinarum 8-10 part, black Semen setariae 50-80 part, Radix Polygalae Wattersii 6-9 part and brown sugar (Saccharum Sinensis Roxb.) 30-33 part respectively according to parts by weight, for subsequent use;
Step 2, by got Radix Aconiti Kusnezoffii Preparata and Rhizoma Alpiniae Officinarum, be ground into the Chinese medicinal granule that particle diameter is 2.5-5.0mm, for subsequent use; Steam 50-70 minute at gained Chinese medicinal granule is placed in 95-100 DEG C, take out and be cooled to 40-45 DEG C, for subsequent use; In got black Semen setariae, add its quality 5-10 water doubly, soak 5-8 hour, pull out and drain, for subsequent use;
Step 3, after being cooled to the Radix Aconiti Kusnezoffii Preparata of 40-45 DEG C and Rhizoma Alpiniae Officinarum Chinese medicinal granule and the black Semen setariae mix homogeneously after soaking after steaming, obtain mixture, add distillers yeast and the quality 15-20 water doubly of its quality 2-3% in the resulting mixture, mix homogeneously is placed in ceramic vessel and ferments 2-3 days again, takes out fermented product; In gained fermented product, add its quality 15-20 water doubly, be heated to 60-70 DEG C and soak 5-6 hour, filter to obtain medicinal liquid A, for subsequent use;
Step 4, got Radix Angelicae Sinensis and Flos Caryophylli powder are broken into the Chinese medicinal granule that diameter is 3.0-8.0mm; In gained Chinese medicinal granule, add got Radix Polygalae Wattersii mix homogeneously, obtain mixture, then add the Bafillus natt of mixture quality 2-3% and the sterilized water of quality 2-4%, again mix homogeneously, be placed in ceramic vessel and ferment 2-3 days, take out tunning; In gained tunning, add tunning quality 3-6 Chinese liquor doubly, soak 3-4 hour post-heating to 50-60 DEG C of insulation 2-3 hour, be then cooled to room temperature, cross leaching filtrate, obtain medical liquid B, for subsequent use;
Step 5, by gained medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C; Got brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan to be fried to coke yellow, joins in medicinal liquid C, is stirred to and dissolves completely, leaves standstill 24-26 hour, filters, and namely gained medicinal liquid prepares the medicated wine for the treatment of rheumatic arthritis.
Step one each crude drug of wine of getting it filled parts by weight be preferably: Radix Aconiti Kusnezoffii Preparata 25 parts, Radix Angelicae Sinensis 8.3 parts, Flos Caryophylli 8.3 parts, Rhizoma Alpiniae Officinarum 8.3 parts, black Semen setariae 70 parts, Radix Polygalae Wattersii 8 parts and brown sugar (Saccharum Sinensis Roxb.) 30 parts.
Beneficial effect is:
1, medicated wine of the present invention is formed by Chinese crude drug compatibilities such as Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Rhizoma Alpiniae Officinarum, Flos Caryophyllis.Wherein Radix Aconiti Kusnezoffii acrid in the mouth, hardship, hot in nature, very toxic, and GUIXIN liver spleen channel, has effect of antalgic, expelling wind and removing dampness, has good effect to anemofrigid-damp arthralgia, numb limbs and tense tendons, is monarch drug; Radix Angelicae Sinensis sweet in the mouth is pungent, warm in nature, has the merit of soothing liver-QI of enriching blood, promoting blood circulation and stopping pain, is used for the treatment of rheumatic Bi syndrome, and the reason that residence has " control wind and first control blood, blood wind is from going out " is ministerial drug; Rhizoma Alpiniae Officinarum acrid in the mouth, hot in nature, return taste warp, can warming spleen and stomach for dispelling cold pain relieving, be adjuvant drug; Flos Caryophylli acrid in the mouth, warm in nature, return spleen lung meridian, have warming middle-JIAO to send down the adverse QI, effect of reinforcing the kidney and supporting YANG.Chinese liquor in addition, warming the meridian and activating blood circulation, dredging collateral cold expelling.Wine assisting drug, wine helps medicine gesture, four medicine compatibilities, and monarch, coordinates mutually, antiinflammatory, ease pain, Eradicates blood stasis and smoothing collaterals of invigorating blood circulation, expelling wind and cold, dampness removing dredging collateral, be intended to drive away invade wind-cold damp pathogen; Heat-clearing and toxic substances removing, reducing swelling and alleviating pain, activating blood circulation to dissipate blood stasis, is intended to solve periarticular inflammation; Row's benefit is helped mutually, attack benefit combines, and is intended to strengthening the body resistance, immunity moderation function; Especially to treatment rheumatic arthritis, there is good therapeutic effect; The medicated wine treatment rheumatic arthritis of simultaneously treating rheumatic arthritis has convenience, safety, cheapness, eutherapeutic feature.
2, the present invention adopts distillers yeast fermentation Radix Aconiti Kusnezoffii and Rhizoma Alpiniae Officinarum Chinese medicinal granule in ceramic vessel, the active ingredient being beneficial to treatment prolapse of lumbar intervertebral disc in Radix Aconiti Kusnezoffii Preparata and Rhizoma Alpiniae Officinarum can be separated out, and reach better therapeutic effect after the medicinal liquid mixing of the Radix Angelicae Sinensis of follow-up bacillus natto to ferment and Flos Caryophylli; Bafillus natt is in the middle of various beneficial bacterium, best to environment resistance, and can go directly one of strain of small intestinal, can change human enteric bacteria and to grow thickly state, help digest function normalization after oral, to make defecation smooth and easy, maintains body physiological balance; And can produce acid, regulating intestinal canal flora, enhancing animal cell immunity is put should; Adopt bacillus natto to ferment Radix Angelicae Sinensis and Flos Caryophylli, except medicine being played to greatest extent except its effect, all right adjusting immunity of human body, improves the utilization rate of medicine.
Detailed description of the invention
Treat a preparation method for the medicated wine of rheumatic arthritis, comprise the following steps:
Step one, get Radix Aconiti Kusnezoffii Preparata 20-25 part, Radix Angelicae Sinensis 8-10 part, Flos Caryophylli 8-10 part, Rhizoma Alpiniae Officinarum 8-10 part, black Semen setariae 50-80 part, Radix Polygalae Wattersii 6-9 part and brown sugar (Saccharum Sinensis Roxb.) 30-33 part respectively according to parts by weight, for subsequent use;
Step 2, by got Radix Aconiti Kusnezoffii Preparata and Rhizoma Alpiniae Officinarum, be ground into the Chinese medicinal granule that particle diameter is 2.5-5.0mm, for subsequent use; Steam 50-70 minute at gained Chinese medicinal granule is placed in 95-100 DEG C, take out and be cooled to 40-45 DEG C, for subsequent use; In got black Semen setariae, add its quality 5-10 water doubly, soak 5-8 hour, pull out and drain, for subsequent use;
Step 3, after being cooled to the Radix Aconiti Kusnezoffii Preparata of 40-45 DEG C and Rhizoma Alpiniae Officinarum Chinese medicinal granule and the black Semen setariae mix homogeneously after soaking after steaming, obtain mixture, add distillers yeast and the quality 15-20 water doubly of its quality 2-3% in the resulting mixture, mix homogeneously is placed in ceramic vessel and ferments 2-3 days again, takes out fermented product; In gained fermented product, add its quality 15-20 water doubly, be heated to 60-70 DEG C and soak 5-6 hour, filter and obtain medicinal liquid, obtain medicinal liquid A, for subsequent use;
Step 4, got Radix Angelicae Sinensis and Flos Caryophylli powder are broken into the Chinese medicinal granule that diameter is 3.0-8.0mm; In gained Chinese medicinal granule, add got Radix Polygalae Wattersii mix homogeneously, obtain mixture, then add the Bafillus natt of mixture quality 2-3% and the sterilized water of quality 2-4%, again mix homogeneously, be placed in ceramic vessel and ferment 2-3 days, take out tunning; In gained tunning, add tunning quality 3-6 Chinese liquor doubly, soak 3-4 hour post-heating to 50-60 DEG C of insulation 2-3 hour, be then cooled to room temperature, cross leaching filtrate, obtain medical liquid B, for subsequent use;
Step 5, by gained medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C; Got brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan to be fried to coke yellow, joins in medicinal liquid C, is stirred to and dissolves completely, leaves standstill 24-26 hour, filters, and namely gained medicinal liquid prepares the medicated wine for the treatment of rheumatic arthritis.
Step one each crude drug of wine of getting it filled parts by weight be preferably: Radix Aconiti Kusnezoffii Preparata 25 parts, Radix Angelicae Sinensis 8.3 parts, Flos Caryophylli 8.3 parts, Rhizoma Alpiniae Officinarum 8.3 parts, black Semen setariae 70 parts, Radix Polygalae Wattersii 8 parts and brown sugar (Saccharum Sinensis Roxb.) 30 parts.
embodiment 1
Treat a preparation method for the medicated wine of rheumatic arthritis, comprise the following steps:
Step one, get Radix Aconiti Kusnezoffii Preparata 25 parts, Radix Angelicae Sinensis 8.3 parts, Flos Caryophylli 8.3 parts, Rhizoma Alpiniae Officinarum 8.3 parts, black Semen setariae 70 parts, Radix Polygalae Wattersii 8 parts and brown sugar (Saccharum Sinensis Roxb.) 30 parts respectively according to parts by weight, for subsequent use;
Step 2, by got Radix Aconiti Kusnezoffii Preparata and Rhizoma Alpiniae Officinarum, be ground into the Chinese medicinal granule that particle diameter is 2.5mm, for subsequent use; Steam 50 minutes at gained Chinese medicinal granule is placed in 95 DEG C, take out and be cooled to 40 DEG C, for subsequent use; In got black Semen setariae, add the water of its quality 5 times, soak 5 hours, pull out and drain, for subsequent use;
Step 3, after being cooled to the Radix Aconiti Kusnezoffii Preparata of 40 DEG C and Rhizoma Alpiniae Officinarum Chinese medicinal granule and the black Semen setariae mix homogeneously after soaking after steaming, obtain mixture, add the distillers yeast of its quality 2% and the water of quality 15 times in the resulting mixture, mix homogeneously is placed in ceramic vessel fermentation 2 days again, takes out fermented product; In gained fermented product, add the water of its quality 15 times, be heated to 60 DEG C and soak 5 hours, filter to obtain medicinal liquid A, for subsequent use;
Step 4, got Radix Angelicae Sinensis and Flos Caryophylli powder are broken into the Chinese medicinal granule that diameter is 3.0mm; In gained Chinese medicinal granule, add got Radix Polygalae Wattersii mix homogeneously, obtain mixture, then add the Bafillus natt of mixture quality 2% and the sterilized water of quality 2%, mix homogeneously again, be placed in ceramic vessel fermentation 2 days, take out tunning; In gained tunning, add the Chinese liquor of tunning quality 3 times, soak post-heating to 50 DEG C insulation in 3 hours 2 hours, be then cooled to room temperature, cross leaching filtrate, obtain medical liquid B, for subsequent use;
Step 5, by gained medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C; Got brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan to be fried to coke yellow, joins in medicinal liquid C, is stirred to and dissolves completely, leaves standstill 24 hours, filters, and namely gained medicinal liquid prepares the medicated wine for the treatment of rheumatic arthritis.
embodiment 2
Treat a preparation method for the medicated wine of rheumatic arthritis, comprise the following steps:
Step one, get Radix Aconiti Kusnezoffii Preparata 20 parts, Radix Angelicae Sinensis 8 parts, Flos Caryophylli 8 parts, Rhizoma Alpiniae Officinarum 8 parts, black Semen setariae 50 parts, Radix Polygalae Wattersii 6 parts and brown sugar (Saccharum Sinensis Roxb.) 30 parts respectively according to parts by weight, for subsequent use;
Step 2, by got Radix Aconiti Kusnezoffii Preparata and Rhizoma Alpiniae Officinarum, be ground into the Chinese medicinal granule that particle diameter is 3.0mm, for subsequent use; Steam 60 minutes at gained Chinese medicinal granule is placed in 98 DEG C, take out and be cooled to 44 DEG C, for subsequent use; In got black Semen setariae, add the water of its quality 8 times, soak 7 hours, pull out and drain, for subsequent use;
Step 3, after being cooled to the Radix Aconiti Kusnezoffii Preparata of 42 DEG C and Rhizoma Alpiniae Officinarum Chinese medicinal granule and the black Semen setariae mix homogeneously after soaking after steaming, obtain mixture, add the distillers yeast of its quality 2.5% and the water of quality 18 times in the resulting mixture, mix homogeneously is placed in ceramic vessel fermentation 2 days again, takes out fermented product; In gained fermented product, add the water of its quality 18 times, be heated to 65 DEG C and soak 5.5 hours, filter to obtain medicinal liquid A, for subsequent use;
Step 4, got Radix Angelicae Sinensis and Flos Caryophylli powder are broken into the Chinese medicinal granule that diameter is 6.0mm; In gained Chinese medicinal granule, add got Radix Polygalae Wattersii mix homogeneously, obtain mixture, then add the Bafillus natt of mixture quality 2.5% and the sterilized water of quality 3%, mix homogeneously again, be placed in ceramic vessel fermentation 3 days, take out tunning; In gained tunning, add the Chinese liquor of tunning quality 4 times, soak post-heating to 55 DEG C insulation in 3.5 hours 2.5 hours, be then cooled to room temperature, cross leaching filtrate, obtain medical liquid B, for subsequent use;
Step 5, by gained medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C; Got brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan to be fried to coke yellow, joins in medicinal liquid C, is stirred to and dissolves completely, leaves standstill 25 hours, filters, and namely gained medicinal liquid prepares the medicated wine for the treatment of rheumatic arthritis.
embodiment 3
Treat a preparation method for the medicated wine of rheumatic arthritis, comprise the following steps:
Step one, get Radix Aconiti Kusnezoffii Preparata 22 parts, Radix Angelicae Sinensis 10 parts, Flos Caryophylli 10 parts, Rhizoma Alpiniae Officinarum 10 parts, black Semen setariae 80 parts, Radix Polygalae Wattersii 9 parts and brown sugar (Saccharum Sinensis Roxb.) 32 parts respectively according to parts by weight, for subsequent use;
Step 2, by got Radix Aconiti Kusnezoffii Preparata and Rhizoma Alpiniae Officinarum, be ground into the Chinese medicinal granule that particle diameter is 5.0mm, for subsequent use; Steam 70 minutes at gained Chinese medicinal granule is placed in 100 DEG C, take out and be cooled to 45 DEG C, for subsequent use; In got black Semen setariae, add the water of its quality 10 times, soak 8 hours, pull out and drain, for subsequent use;
Step 3, after being cooled to the Radix Aconiti Kusnezoffii Preparata of 45 DEG C and Rhizoma Alpiniae Officinarum Chinese medicinal granule and the black Semen setariae mix homogeneously after soaking after steaming, obtain mixture, add the distillers yeast of its quality 3% and the water of quality 20 times in the resulting mixture, mix homogeneously is placed in ceramic vessel fermentation 3 days again, takes out fermented product; In gained fermented product, add the water of its quality 20 times, be heated to 70 DEG C and soak 6 hours, filter to obtain medicinal liquid A, for subsequent use;
Step 4, got Radix Angelicae Sinensis and Flos Caryophylli powder are broken into the Chinese medicinal granule that diameter is 8.0mm; In gained Chinese medicinal granule, add got Radix Polygalae Wattersii mix homogeneously, obtain mixture, then add the Bafillus natt of mixture quality 3% and the sterilized water of quality 4%, mix homogeneously again, be placed in ceramic vessel fermentation 3 days, take out tunning; In gained tunning, add the Chinese liquor of tunning quality 6 times, soak post-heating to 60 DEG C insulation in 4 hours 3 hours, be then cooled to room temperature, cross leaching filtrate, obtain medical liquid B, for subsequent use;
Step 5, by gained medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C; Got brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan to be fried to coke yellow, joins in medicinal liquid C, is stirred to and dissolves completely, leaves standstill 26 hours, filters, and namely gained medicinal liquid prepares the medicated wine for the treatment of rheumatic arthritis.
clinical trial
1, experimental subject: patient 200 example suffering from rheumatic arthritis through regular examination in hospital, there is the symptom of osteoarthrosis local redness, pain, heating and limitation of movement in patient.
2, Therapeutic Method: the medicated wine of oral medication treatment rheumatic arthritis, (medicine) being taken before meal is with once sooner or later, each 5 milliliters, calculates, do not eat sugar and sweet food within 2 hours from when taking medicine, and overheated supercool thing.The auxiliary medicated wine by treatment rheumatic arthritis is outer is in right amount coated with arthritis sore spot; It within 7 days, is 1 course for the treatment of.
3, evaluation criterion is treated:
Cure: disease disappears, muscle is light, osteoarthrosis freedom of movement, and untoward reaction disappears;
Effective: pain relief, inflammation alleviates, adverse reaction reduction;
Effective: to meet healing or effective standard.
Invalid: the state of an illness is unchanged on inspection, without improvement sign.
4, therapeutic effect:
To 200 example age 16-62 year rheumatoid arthritis patients treat, wherein cure rheumatic arthritis 150 example, effective 43 examples, effective percentage reaches 96.5%, result proves that the present invention treats the medicated wine of rheumatic arthritis, formula is reasonable, and preparation method is reasonable, has good therapeutical effect to rheumatic arthritis.
Bafillus natt of the present invention is common Bafillus natt strain, buys obtain by market.
Claims (2)
1. treat a preparation method for the medicated wine of rheumatic arthritis, it is characterized in that: comprise the following steps:
Step one, get Radix Aconiti Kusnezoffii Preparata 20-25 part, Radix Angelicae Sinensis 8-10 part, Flos Caryophylli 8-10 part, Rhizoma Alpiniae Officinarum 8-10 part, black Semen setariae 50-80 part, Radix Polygalae Wattersii 6-9 part and brown sugar (Saccharum Sinensis Roxb.) 30-33 part respectively according to parts by weight, for subsequent use;
Step 2, by got Radix Aconiti Kusnezoffii Preparata and Rhizoma Alpiniae Officinarum, be ground into the Chinese medicinal granule that particle diameter is 2.5-5.0mm, for subsequent use; Steam 50-70 minute at gained Chinese medicinal granule is placed in 95-100 DEG C, take out and be cooled to 40-45 DEG C, for subsequent use; In got black Semen setariae, add its quality 5-10 water doubly, soak 5-8 hour, pull out and drain, for subsequent use;
Step 3, after being cooled to the Radix Aconiti Kusnezoffii Preparata of 40-45 DEG C and Rhizoma Alpiniae Officinarum Chinese medicinal granule and the black Semen setariae mix homogeneously after soaking after steaming, obtain mixture, add distillers yeast and the 15-20 water doubly of its quality 2-3% in the resulting mixture, mix homogeneously is placed in ceramic vessel and ferments 2-3 days again, takes out fermented product; In gained fermented product, add its quality 15-20 water doubly, be heated to 60-70 DEG C and soak 5-6 hour, filter to obtain medicinal liquid A, for subsequent use;
Step 4, got Radix Angelicae Sinensis and Flos Caryophylli powder are broken into the Chinese medicinal granule that diameter is 3.0-8.0mm; In gained Chinese medicinal granule, add got Radix Polygalae Wattersii mix homogeneously, obtain mixture, then add the Bafillus natt of mixture quality 2-3% and the sterilized water of 2-4%, again mix homogeneously, be placed in ceramic vessel and ferment 2-3 days, take out tunning; In gained tunning, add tunning quality 3-6 Chinese liquor doubly, soak 3-4 hour post-heating to 50-60 DEG C of insulation 2-3 hour, be then cooled to room temperature, cross leaching filtrate, obtain medical liquid B, for subsequent use;
Step 5, by gained medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C; Got brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan to be fried to coke yellow, joins in medicinal liquid C, is stirred to and dissolves completely, leaves standstill 24-26 hour, filters, and namely gained medicinal liquid prepares the medicated wine for the treatment of rheumatic arthritis.
2. the preparation method of the medicated wine for the treatment of rheumatic arthritis as claimed in claim 1, is characterized in that: step one the parts by weight of each crude drug of wine of getting it filled be: Radix Aconiti Kusnezoffii Preparata 25 parts, Radix Angelicae Sinensis 8.3 parts, Flos Caryophylli 8.3 parts, Rhizoma Alpiniae Officinarum 8.3 parts, black Semen setariae 70 parts, Radix Polygalae Wattersii 8 parts and brown sugar (Saccharum Sinensis Roxb.) 30 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410549736.4A CN104306852B (en) | 2014-10-17 | 2014-10-17 | A kind of preparation method of the medicinal liquor for treating rheumatic arthritis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410549736.4A CN104306852B (en) | 2014-10-17 | 2014-10-17 | A kind of preparation method of the medicinal liquor for treating rheumatic arthritis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104306852A true CN104306852A (en) | 2015-01-28 |
| CN104306852B CN104306852B (en) | 2017-06-16 |
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| CN107224551A (en) * | 2017-08-03 | 2017-10-03 | 河南省四知堂制药有限公司 | A kind of Chinese medicine composition and preparation method for repairing skin |
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| CN101095710A (en) * | 2007-07-11 | 2008-01-02 | 浙江大学 | Method for improving the main efficacy composition of panax notoginseng through zymolysis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107224551A (en) * | 2017-08-03 | 2017-10-03 | 河南省四知堂制药有限公司 | A kind of Chinese medicine composition and preparation method for repairing skin |
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