CN107224551A - A kind of Chinese medicine composition and preparation method for repairing skin - Google Patents
A kind of Chinese medicine composition and preparation method for repairing skin Download PDFInfo
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- CN107224551A CN107224551A CN201710655009.XA CN201710655009A CN107224551A CN 107224551 A CN107224551 A CN 107224551A CN 201710655009 A CN201710655009 A CN 201710655009A CN 107224551 A CN107224551 A CN 107224551A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9062—Alpinia, e.g. red ginger or galangal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
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Abstract
The invention discloses a kind of Chinese medicine composition and preparation method for repairing skin, the bulk drug composition of the composition is：The 27g of wild aconite root 23, the 8.5g of Radix Angelicae Sinensis 8.0, the 8.5g of galangal 8.0, the 8.5g of cloves 8.0, the 8.0g of peppermint 7.5, the 8.0g of borneol 7.5.The Chinese medicine composition that above-mentioned raw materials medicine is made is repairing skin, improve skin microcirculation, strengthen cutaneous immunisation power, mitigate inflammation caused by various ringworms, malignant boil, carbuncle, sore etc., alleviate the itch of multiple dermatosis initiation, swell and ache, for burn and scald, hurt, abrade, burn, tan severely, frostbite, soft tissue injury, and there is significant therapeutic effect in terms of the reparation of senile plaque expelling, whelk etc., instant effect, expense is low, it is easy to use in terms of have significant therapeutic effect, instant effect, expense is low, easy to use.
Description
Technical field
The present invention relates to field of traditional Chinese, more particularly to a kind of Chinese traditional medicine composition and preparation method for repairing skin.
Background technology
Skin is an outmost Rotating fields for human body, is a maximum organ of human body.It is both the sensation of nervous system
Device, is effector again, hot and cold, pain, emotional change etc. mechanically and chemically cause to sexual stimulus all reflectivity skin vasoconstriction and
Diastole, arrectores pilorum contraction, sweat gland secretion, the change of capillary of skin permeability.Skin covers whole body, and it makes various groups in vivo
Knit with organ from physical, mechanicalness, invasion and attack chemically with pathogenic microorganism.
Skin damage is the phenomenon being commonly encountered in people's daily life, sometimes because skin is injured unexpectedly, such as burn,
Scald, sunburn, frostbite, scratch, incised wound etc., sometimes occur such as tinea, sore because of ill on skin, itch, swell and ache, burst
Ulcer etc., occurs the phenomenons such as whelk, senile plaque expelling sometimes on skin, above-mentioned phenomenon often makes people be unable to bear being scratched with hand,
And further result in skin damage, it is difficult to recover.
The content of the invention
To solve problems of the prior art, the present invention proposes a kind of Chinese medicine composition for repairing skin and preparation side
Method, can repair impaired skin, improve skin microcirculation, strengthen cutaneous immunisation power, mitigate various ringworms, malignant boil, carbuncle, sore etc. and draw
The inflammation risen.
To achieve the above object, the present invention proposes a kind of Chinese medicine composition for repairing skin, the bulk drug of the composition
Constitute and be：Wild aconite root, Radix Angelicae Sinensis, galangal, cloves, peppermint and borneol.
It is preferred that, wild aconite root 23-27g, Radix Angelicae Sinensis 8.0-8.5g, galangal 8.0-8.5g, cloves 8.0-8.5g, peppermint 7.5-
8.0g, borneol 7.5-8.0g.
The Chinese medicine composition of described reparation skin, the Chinese medicine composition adds customary adjuvant according to common process and is made
Clinically acceptable external preparation.
Described pharmaceutical composition adds the external preparation that customary adjuvant is prepared according to common process.
The external preparation includes spray, liniment, paste, paste, lotion or patch.
The invention provides a kind of method for the Chinese medicine composition for preparing the reparation skin, this method comprises the following steps
：
(a) wild aconite root, Radix Angelicae Sinensis, galangal, cloves, peppermint and borneol are weighed according to selected quality, be respectively crushed into after fine powder
Fine powder, sieving for standby are ground into after mixing or mixing；
(b) take above-mentioned fine powder, add customary adjuvant according to common process be made clinically acceptable spray, liniment, paste, wash
Agent or patch.
The invention provides a kind of method for the Chinese medicine composition for preparing the reparation skin, this method comprises the following steps
：
(a) wild aconite root 25g, Radix Angelicae Sinensis 8.3g, galangal 8.3g, cloves 8.3g, peppermint 7.5g and ice are weighed according to selected quality
Piece 7.5g, is respectively crushed into after coarse powder and mixes or be ground into coarse powder, sieving for standby after mixing；
(b) by step（a）Obtained mixture adds 64.9g ethanol, and deionized water 40g is soaked, and soak time is 24
Hour；
(c) step（b）Mixture, heating extraction 3 times, every time 1.5 hours；The dregs of a decoction are squeezed, merge decoction；Stand 24 small
When, filtration takes supernatant, plus white wine to adjust total amount to 1000ml；
(d) customary adjuvant is added, clinically acceptable spray, liniment, paste, lotion or patch is made according to common process.
The invention provides a kind of Chinese medicine composition prepared by above-mentioned method.
Present invention also offers a kind of application of described Chinese medicine composition in the medicine for repairing skin is prepared.
Beneficial effect：
The Chinese medicine composition of the present invention for repairing skin, by choosing wild aconite root, Radix Angelicae Sinensis, galangal, cloves, peppermint and ice
Piece is that the Chinese medicine composition that bulk drug is made is repairing skin, improves skin microcirculation, strengthens cutaneous immunisation power, mitigates various tinea
Inflammation caused by disease, malignant boil, carbuncle, sore etc., alleviates itch that multiple dermatosis triggers, swells and ache, for burn and scald, incised wound, scratch, bright
There is significant therapeutic effect in terms of the reparation of wound, sunburn, frostbite, soft tissue injury, and senile plaque expelling, whelk etc., see
Effect is fast, and expense is low, easy to use, and clinical cure rate is up to 95.3%.
Experimental example Chinese medicine composition of the present invention repairs the clinical observation of skin
1st, data and method
Clinical data：The present invention carries out clinical treatment observation to 120 patients with skin symptom.
The evaluation criterion of clinical therapeutic efficacy is：
（1）Clinical cure：Original symptom disappears；
（2）It is effective：Original symptom partial disappearance；
（3）Take a turn for the better：Original state of an illness has mitigated；
（4）It is invalid：Symptom and sign is unchanged.
Medication：Paste prepared by the spray and embodiment 3 that respectively prepared by Example 1 is sprayed on or applied in right amount
It is overlying on the site of disease of patient, every 10 days courses for the treatment of, daily 3 times.
2nd, treatment results
After the traditional Chinese medicine composition for treating 2-3 course for the treatment of of above-mentioned 60 patients prepared using the embodiment of the present invention 2, observation is described
The treatment results of 60 patients, wherein curing 57, effective 0, take a turn for the better 2, invalid 1, and cure rate is
96.7%。
After the traditional Chinese medicine composition for treating 2-3 course for the treatment of of other 60 patients prepared using the embodiment of the present invention 3, see
The treatment results of the reparation skin of 60 patients are examined, wherein curing 58, effective 1, are taken a turn for the better 0, invalid 0
Example, cure rate is 96.7%.
Toxic side effect：After treatment is finished, check blood urine routine, stool, the heart, liver and the no abnormal change of renal function.
Above-mentioned case is paid a return visit after 3 months, no patients with recurrent.
3rd, conclusion
Chinese medicine composition of the present invention repair skin in terms of have significant therapeutic effect, its cure rate up to 95%,
Short treating period, instant effect, and have no toxic side effect.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to
Limit the present invention.
The spray formulation of embodiment 1
The Chinese medicine composition of the reparation skin of the present embodiment, its formula is as follows：
Wild aconite root 24g, Radix Angelicae Sinensis 8.2g, galangal 8.2g, cloves 8.2g, peppermint 7.5g and borneol 7.5g, the Chinese medicine composition
Spray is prepared into according to following steps：
(a) wild aconite root, Radix Angelicae Sinensis, galangal, cloves, peppermint and borneol are weighed according to selected mass number, is respectively crushed into fine powder
Fine powder is ground into after mixing or mix afterwards, 40 mesh sieves are crossed standby；
(b) above-mentioned fine powder is taken, customary adjuvant is added and clinically acceptable spray is made according to common process.
The spray formulation of embodiment 2
Wild aconite root 25g, Radix Angelicae Sinensis 8.3g, galangal 8.3g, cloves 8.3g, peppermint 7.8g and borneol 7.8g, the Chinese medicine composition
Spray is prepared into according to following steps：
(a) wild aconite root 25g, Radix Angelicae Sinensis 8.3g, galangal 8.3g, cloves 8.3g, peppermint 7.5g and ice are weighed according to selected quality
Piece 7.5g, is respectively crushed into after coarse powder and mixes or be ground into coarse powder, sieving for standby after mixing；
(b) by step（a）Obtained mixture adds 64.9g ethanol, and deionized water 40g is soaked, and soak time is 24
Hour；
(c) step（b）Mixture, heating extraction 3 times, every time 1.5 hours；The dregs of a decoction are squeezed, merge decoction；Stand 24 small
When, filtration takes supernatant, plus white wine to adjust total amount to 1000ml；
(d) customary adjuvant is added, clinically acceptable spray is made according to common process.
The paste formulation of embodiment 3
(a) wild aconite root 25g, Radix Angelicae Sinensis 8.2g, galangal 8.2g, cloves 8.2g, peppermint 7.5g and ice are weighed according to selected quality
Piece 7.5g, is respectively crushed into after coarse powder and mixes or be ground into coarse powder after mixing, add the ethanol of 5 times of quality of said mixture, enter
Row immersion is run through, and soak time is 24 hours；Secondary, the water of first time plus 5 times of drug weights is added water to cook, 2.5 are decocted small
When, second plus 4 times of amount water are decocted 2 hours, filtration, merging filtrate is stood overnight, and takes supernatant concentration to 60 DEG C of phases
To the medicinal extract that density is 1.2-1.25.
(b) medicinal extract is taken, customary adjuvant is added and clinically acceptable paste is made according to common process.
The Chinese medicine composition of the present invention can also alleviate the malaise symptoms such as neck, shoulder, waist, gonalgia, promote health.
Obviously, above-described embodiment is only intended to clearly illustrate example, and the not restriction to embodiment.It is right
For those of ordinary skill in the art, can also make on the basis of the above description it is other it is various forms of change or
Change.There is no necessity and possibility to exhaust all the enbodiments.And the obvious change thus extended out or
Among changing still in the protection domain of the invention.
Claims (9)
1. a kind of Chinese medicine composition for repairing skin, it is characterised in that：The bulk drug of the composition is constituted：Wild aconite root, when
Return, galangal, cloves, peppermint and borneol.
2. the Chinese medicine composition according to claim 1 for repairing skin, it is characterised in that：The bulk drug group of the composition
Turn into：Wild aconite root 23-27g, Radix Angelicae Sinensis 8.0-8.5g, galangal 8.0-8.5g, cloves 8.0-8.5g, peppermint 7.5-8.0g, borneol
7.5-8.0g。
3. the Chinese medicine composition according to claim 1 or 2 for repairing skin, it is characterised in that：The Chinese medicine composition is pressed
More solito technique adds customary adjuvant and clinically acceptable external preparation is made.
4. using the Chinese medicine composition of the reparation skin described in claim 1 or 2 customary adjuvant is added to prepare according to common process
Obtained external preparation.
5. external preparation according to claim 4, it is characterised in that：The external preparation include spray, liniment, paste,
Paste, lotion or patch.
6. a kind of method for preparing the Chinese medicine composition that skin is repaired as described in claims 1 to 3 any claim, this method
Comprise the following steps：
Wild aconite root, Radix Angelicae Sinensis, galangal, cloves, peppermint and borneol are weighed according to selected quality, is respectively crushed into after fine powder and mixes
Or it is ground into fine powder, sieving for standby after mixing；
Above-mentioned fine powder is taken, customary adjuvant is added and clinically acceptable spray, liniment, paste, lotion is made according to common process
Or patch.
7. a kind of method for preparing the Chinese medicine composition that skin is repaired as described in claims 1 to 3 any claim, this method
Comprise the following steps：
(a) wild aconite root 25g, Radix Angelicae Sinensis 8.3g, galangal 8.3g, cloves 8.3g, peppermint 7.5g and ice are weighed according to selected quality
Piece 7.5g, is respectively crushed into after coarse powder and mixes or be ground into coarse powder, sieving for standby after mixing；
(b) by step（a）Obtained mixture adds 64.9g ethanol, and deionized water 40g is soaked, and soak time is 24
Hour；
(c) step（b）Mixture, heating extraction 3 times, every time 1.5 hours；The dregs of a decoction are squeezed, merge decoction；Stand 24 small
When, filtration takes supernatant, plus white wine to adjust total amount to 1000ml；
(d) customary adjuvant is added, clinically acceptable spray, liniment, paste, lotion or patch is made according to common process.
8. the Chinese medicine composition prepared according to any method of claim 6 or 7.
9. according to application of any described Chinese medicine composition of claims 1 to 3 or 9 in the medicine for repairing skin is prepared.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710655009.XA CN107224551A (en) | 2017-08-03 | 2017-08-03 | A kind of Chinese medicine composition and preparation method for repairing skin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710655009.XA CN107224551A (en) | 2017-08-03 | 2017-08-03 | A kind of Chinese medicine composition and preparation method for repairing skin |
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| Publication Number | Publication Date |
|---|---|
| CN107224551A true CN107224551A (en) | 2017-10-03 |
Family
ID=59957917
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710655009.XA Pending CN107224551A (en) | 2017-08-03 | 2017-08-03 | A kind of Chinese medicine composition and preparation method for repairing skin |
Country Status (1)
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104306852A (en) * | 2014-10-17 | 2015-01-28 | 河南省四知堂制药有限公司 | Preparation method of medicinal liquor for treating rheumatic arthritis |
-
2017
- 2017-08-03 CN CN201710655009.XA patent/CN107224551A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104306852A (en) * | 2014-10-17 | 2015-01-28 | 河南省四知堂制药有限公司 | Preparation method of medicinal liquor for treating rheumatic arthritis |
Non-Patent Citations (2)
| Title |
|---|
| 刘大有主编: "《全蝎 僵蚕生产技术》", 31 May 2004, 中国农业出版社 * |
| 郑秀春: "浅谈五毒膏的制剂工艺", 《吉林中医药》 * |
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| PB01 | Publication | ||
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Application publication date: 20171003 |