CN108888740A - A kind of bone strengthening ostalgia emplastrum and preparation method thereof - Google Patents
A kind of bone strengthening ostalgia emplastrum and preparation method thereof Download PDFInfo
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- CN108888740A CN108888740A CN201811146668.1A CN201811146668A CN108888740A CN 108888740 A CN108888740 A CN 108888740A CN 201811146668 A CN201811146668 A CN 201811146668A CN 108888740 A CN108888740 A CN 108888740A
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Abstract
The invention discloses a kind of bone strengthening ostalgia emplastrum and preparation method thereof, the emplastrum includes Moschus, safflower, Radix Salviae Miltiorrhizae, Radix Notoginseng, olibanum, pilose antler, radix saposhnikoviae, centipede, thizoma curculiginis, the bletilla striata, the root of Chinese clematis, Caulis Spatholobi, honeycomb, turmeric and borneol.Emplastrum clearing and activating the channels and collaterals that the present invention is prepared under specific proportion using various Chinese medicine materials, blood stasis dispersing and fresh blood promoting, analgesic eliminating impediment, warming yang and benefiting qi, strengthen muscles and bones, promoting blood circulation and stopping pain the effect of, the emplastrum short treating period, it is quick, and raw material is all made of Chinese medicine, has no toxic side effect；Emplastrum penetration of the invention is strong, and muscles and bones of going directly, activating microcirculation and removing stasis medicinal analgesic effect is obvious, and smearing class emplastrum dosage is flexible, and curative effect of medication is above other similar products；Emplastrum of the invention uses water concentration extraction, is boiled with honey, so that the effective component of each raw material proposes out, ensure that medicinal ingredient is injury-free, drug effect is made to be improved.
Description
Technical field
The invention belongs to pharmaceutical technology fields, and in particular to a kind of bone strengthening ostalgia emplastrum and preparation method thereof.
Background technique
Ostalgia refers to whole body or a certain local skeleton pain, there is lumbago, limbs pain, arthralgia, is that a variety of causes is such as anxious
The symptom of pain, most commonly caput femoris necrosis, bone around bone caused by property damage, rheumatism, chronic strain infection, tumour etc.
Folding, Osteoarthritis, calcanean spur, disc herniation, the above reason can cause coronary insufficiency to cause chest
Back pain, vasculitis pain, tennis elbow, rheumatism cause courbature, facial paralysis to cause the diseases such as headache tinnitus insomnia.
Due to the aging of body, physical function changes the modern middle-aged and the old, and body is often in a kind of shape of inferior health
State.It can usually feel pelvic bone pain, insufficiency of vital energy and blood, soreness of bones and muscles, it is easier to suffer from the diseases such as arthritis, rheumatism, rheumatoid.Year
Light people's usually body building, is also subjected to sport injury during exercise, pulls a muscle when serious, damages muscles and bones, causes fracture etc.
Serious damage, if the above illness and the pain of injury develop as one pleases without conditioning and treatment, extreme influence are good for human body
Health causes serious sequelae.
Lack effective liniment treatment in the prior art, the limitation of deep layer bone joint pain, such as ischemic cannot be alleviated
Property caput femoris necrosis caused by pain caused by hip arthralgia, oldness caput femoris necrosis, the prominent compressing spinal cord of intervertebral disc of cervical vertebra
Caused neck and shoulder part is stiff, headache head is numb, chirobrachialgia, and severe pain caused by fracturing cannot walk with descending with thigh bone pain
Equal diseases, cause patient to act on body by above-mentioned pain, have seriously affected the life of patient, work quality, existing external application
The treatment time of drug is long, and penetration is poor, and effect is poor.
For these reasons, the present invention is specifically proposed.
Summary of the invention
In order to solve problem above of the existing technology, the present invention provides a kind of bone strengthening ostalgia emplastrum and its preparation sides
Method, bone strengthening ostalgia emplastrum prepared by the present invention have clearing and activating the channels and collaterals, blood stasis dispersing and fresh blood promoting, analgesic eliminating impediment, warming yang and benefiting qi, strengthen muscles and bones,
The effect of promoting blood circulation and stopping pain, the emplastrum short treating period have no toxic side effect, and penetration is strong, quick.
To achieve the goals above, the present invention adopts the following technical scheme that：
A kind of bone strengthening ostalgia emplastrum, the emplastrum include Moschus, safflower, Radix Salviae Miltiorrhizae, Radix Notoginseng, olibanum, pilose antler, radix saposhnikoviae,
Centipede, thizoma curculiginis, the bletilla striata, the root of Chinese clematis, Caulis Spatholobi, honeycomb, turmeric and borneol.
Moschus, which is called, loses perfume, navel perfume, hearty cord perfume, when the door etc., is point of the glandular sac between the navel and genitals of male musk deer
Secretion is in granular form or blocky after dry, has special fragrance, there is bitter taste, fragrance can be made, can also be used as medicine.For blood
Stasis of blood menostasis, note of the ancient Chinese lump in the abdomen, trusted subordinate sudden and violent pain, traumatic injury, wind-cold-dampness arthralgia, activating microcirculation and removing stasis medicinal etc..
Safflower has activating microcirculation and removing stasis medicinal, removing pattogenic heat from the blood and toxic material from the body, resolving stagnation for tranquilization, beautifying face and moistering lotion and other effects, to prevention cardiovascular and cerebrovascular disease
Disease, adjusting hepatic and renal function etc. are also helpful.
Radix Salviae Miltiorrhizae, Chinese medicine name.For the dry root and rhizome of Lamiaceae plant Radix Salviae Miltiorrhizae.Spring, the excavation of two season of autumn, silt is removed, is done
It is dry.National most area is all distributed.It is inducing meastruation to relieve menalgia with promoting blood circulation, the effect of relieving restlessness and restlessness, cool blood to disappear carbuncle.
Radix Notoginseng is for spitting blood, haematemesis, bleeding from five sense organs or subcutaneous tissue, hematochezia, metrorrhagia and metrostaxis, traumatic hemorrhage, chest and abdomen shouting pain, tumbling and swelling.
Olibanum regulating qi and activating blood, analgesic therapy, detumescence, myogenic.Belong to the blood-activating analgesic classified under drug for invigorating blood circulation and eliminating stasis.
Pilose antler has stronger antifatigue effect, can enhance tolerance to cold, acceleration of wound healing and stimulation adrenal cortex
Function.Therefore pilose antler is traditional tonic, is used for strong, kidney tonifying, Yiyang.
Radix saposhnikoviae has the effect of expelling pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, relieving convulsion.
Centipede has relieve the wind syndrome antispastic, removes obstruction in channels to relieve pain, dispersing pathogen accumulation.
Thizoma curculiginis has the function of tonifying the kidney and support yang, benefiting essence-blood, strengthening the bones and muscles and promoting circulation of blood detumescence.
Bletilla striata function with cure mainly：Astringing to arrest bleeding, detumescence and promoting granulation are spitted blood for hemoptysis, traumatic hemorrhage, sore swollen toxin, skin
Chap；Pulmonary tuberculosis hemoptysis, ulcer haemorrhage.
The root of Chinese clematis has wind-damp dispelling, the effect of degrading the channel.
Caulis Spatholobi can treat waist and knee joints pain, rheumatic arthralgia, extremity numbness caused by rheumatism.
Honeycomb is usually used in sore swollen toxin, acute mastitis, scrofula, skin stubborn dermatitis, the fungal infection of the hand, toothache, rheumatic arthralgia.
Turmeric cures mainly chest and abdomen swelling and pain, shoulder arm numbness pain, it is pained unbearably, postpartum blood pain, ringworm sore is initial, irregular menstruation, and amenorrhoea is fallen
Play damage.
Borneol promotes the absorption of drug, and cooperation other drugs have the function of removing heat from the heart to restore to consciousness.
Further, according to parts by weight, the emplastrum includes Moschus 8-12 parts by weight, safflower 45-55 parts by weight, pellet
Join 45-55 parts by weight, Radix Notoginseng 10-14 parts by weight, olibanum 45-55 parts by weight, pilose antler 15-25 parts by weight, radix saposhnikoviae 55-65 weight
Part, centipede 30-40 parts by weight, thizoma curculiginis 45-55 parts by weight, bletilla striata 45-55 parts by weight, root of Chinese clematis 75-85 parts by weight, Caulis Spatholobi
95-105 parts by weight, honeycomb 25-35 parts by weight, turmeric 95-105 parts by weight and borneol 105-110 parts by weight.
Further, according to parts by weight, the emplastrum includes 10 parts by weight of Moschus, 50 parts by weight of safflower, Radix Salviae Miltiorrhizae 50
Parts by weight, 12 parts by weight of Radix Notoginseng, 50 parts by weight of olibanum, 20 parts by weight of pilose antler, windproof 60 parts by weight, 35 parts by weight of centipede, thizoma curculiginis
50 parts by weight, 50 parts by weight of the bletilla striata, 80 parts by weight of the root of Chinese clematis, 100 parts by weight of Caulis Spatholobi, 30 parts by weight of honeycomb, 100 weight of turmeric
Part and 100 parts by weight of borneol.
Emplastrum application method of the invention selects suitable dressing patch, uses spatula according to the of different sizes of painful area
Plaster is dipped in, uniformly applies and smoothes out on dressing patch, be affixed on affected part, removed after 24 hours.
A kind of preparation method of the bone strengthening ostalgia emplastrum, the method include the following steps：
(1) it is weighed according to the weight of each raw material spare；
(2) weighed each raw material is crushed in addition to borneol, is sieved, obtains traditional Chinese medicine powder；
(3) traditional Chinese medicine powder is impregnated into the water, then extracts, is concentrated under reduced pressure, obtains traditional Chinese medicinal ointment A；
(4) honey will be added in traditional Chinese medicinal ointment A, is boiled, it is cooling, obtain traditional Chinese medicinal ointment B；
(5) weighed borneol is added in traditional Chinese medicinal ointment B, is stirred evenly, is applied on dressing patch, obtain the patch
Cream.
Further, 90-110 mesh is crossed in step (2).
Further, the mass ratio of traditional Chinese medicine powder and water is 1:6-8.
Further, honey and the mass ratio of traditional Chinese medicine powder are 4-6:1-3.
Further, tanning temperature is 110-120 DEG C in step (4), and the tanning time is 5-7 hours.
Further, tanning temperature is 115 DEG C in step (4), and the tanning time is 6 hours.
Further, 20-25 DEG C is cooled in step (4).
Compared with prior art, beneficial effects of the present invention are as follows：
(1) emplastrum clearing and activating the channels and collaterals, blood stasis dispersing and fresh blood promoting, analgesic that the present invention is prepared under specific proportion using various Chinese medicine materials
Eliminating impediment, warming yang and benefiting qi, strengthen muscles and bones, promoting blood circulation and stopping pain the effect of, the emplastrum short treating period is quick, and during raw material is all made of
Medicinal material has no toxic side effect；
(2) emplastrum penetration of the invention is strong, and muscles and bones of going directly, activating microcirculation and removing stasis medicinal analgesic effect is obvious, smears class emplastrum dosage
Flexibly, curative effect of medication is above other similar products；
(3) emplastrum of the invention uses water concentration extraction, is boiled with honey, so that the effective component of each raw material is adequately released
It releases, ensure that medicinal ingredient is injury-free, drug effect is made to be improved.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical solution of the present invention will be carried out below
Detailed description.Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Base
Embodiment in the present invention, those of ordinary skill in the art are obtained all without making creative work
Other embodiment belongs to the range that the present invention is protected.
Embodiment 1
A kind of bone strengthening ostalgia emplastrum of the present embodiment, the emplastrum include Moschus 8g, safflower 45g, Radix Salviae Miltiorrhizae 45g, three
Seven 10g, olibanum 45g, pilose antler 15g, radix saposhnikoviae 55g, centipede 30g, thizoma curculiginis 45g, bletilla striata 45g, root of Chinese clematis 75g, Caulis Spatholobi 95g, bee
Room 25g, turmeric 95g and borneol 105g.
The preparation method of the bone strengthening ostalgia emplastrum of the present embodiment, includes the following steps：
(1) it is weighed according to the weight of each raw material spare；
(2) weighed each raw material is crushed in addition to borneol, 90 meshes of being sieved obtain traditional Chinese medicine powder；
(3) traditional Chinese medicine powder is impregnated into the water, the mass ratio of traditional Chinese medicine powder and water is 1:6, then extract, depressurize it is dense
Contracting, obtains traditional Chinese medicinal ointment A；
(4) honey will be added in traditional Chinese medicinal ointment A, the mass ratio of honey and traditional Chinese medicine powder is 4:1, it is boiled, tanning temperature is
110 DEG C, the tanning time is 5 hours, is cooled to 20 DEG C, obtains traditional Chinese medicinal ointment B；
(5) weighed borneol is added in traditional Chinese medicinal ointment B, is stirred evenly, is applied on dressing patch, obtain the patch
Cream.
Embodiment 2
A kind of bone strengthening ostalgia emplastrum of the present embodiment, the emplastrum include Moschus 10g, safflower 50g, Radix Salviae Miltiorrhizae 50g, three
Seven 12g, olibanum 50g, pilose antler 20g, radix saposhnikoviae 60g, centipede 35g, thizoma curculiginis 50g, bletilla striata 50g, root of Chinese clematis 80g, Caulis Spatholobi 100g, bee
Room 30g, turmeric 100g and borneol 100g.
The preparation method of the bone strengthening ostalgia emplastrum of the present embodiment, includes the following steps：
(1) it is weighed according to the weight of each raw material spare；
(2) weighed each raw material is crushed in addition to borneol, 100 meshes of being sieved obtain traditional Chinese medicine powder；
(3) traditional Chinese medicine powder is impregnated into the water, the mass ratio of traditional Chinese medicine powder and water is 1:7, then extract, depressurize it is dense
Contracting, obtains traditional Chinese medicinal ointment A；
(4) honey will be added in traditional Chinese medicinal ointment A, the mass ratio of honey and traditional Chinese medicine powder is 5:2, it is boiled, tanning temperature is
115 DEG C, the tanning time is 6 hours, is cooled to 23 DEG C, obtains traditional Chinese medicinal ointment B；
(5) weighed borneol is added in traditional Chinese medicinal ointment B, is stirred evenly, is applied on dressing patch, obtain the patch
Cream.
Embodiment 3
A kind of bone strengthening ostalgia emplastrum of the present embodiment, the emplastrum include Moschus 12g, safflower 55g, Radix Salviae Miltiorrhizae 55g, three
Seven 14g, olibanum 55g, pilose antler 25g, radix saposhnikoviae 65g, centipede 40g, thizoma curculiginis 55g, bletilla striata 55g, root of Chinese clematis 85g, Caulis Spatholobi 105g, bee
Room 35g, turmeric 105g and borneol 110g.
The preparation method of the bone strengthening ostalgia emplastrum of the present embodiment, includes the following steps：
(1) it is weighed according to the weight of each raw material spare；
(2) weighed each raw material is crushed in addition to borneol, 110 meshes of being sieved obtain traditional Chinese medicine powder；
(3) traditional Chinese medicine powder is impregnated into the water, the mass ratio of traditional Chinese medicine powder and water is 1:8, then extract, depressurize it is dense
Contracting, obtains traditional Chinese medicinal ointment A；
(4) honey will be added in traditional Chinese medicinal ointment A, the mass ratio of honey and traditional Chinese medicine powder is 2:1, it is boiled, tanning temperature is
120 DEG C, the tanning time is 7 hours, is cooled to 25 DEG C, obtains traditional Chinese medicinal ointment B；
(5) weighed borneol is added in traditional Chinese medicinal ointment B, is stirred evenly, is applied on dressing patch, obtain the patch
Cream.
Case 1
So-and-so is congratulated, female, 60 years old, people from Xiamen City, Fujian Province examined, before half wheat harvesting period, facial paralysis occur on September 12nd, 2017
Etc. symptoms, right face cannot close one's eyes frown, right volume line disappears, dehiscing, bicker is askew cannot whistle to upper left side on then right side, silent
Gas leakage, Ren Zhonggou is to the left, and diet stops gathering behind the right portion Jia, difficulty speaking, cephalic pain, auris dextra and having volume side, neck-shoulder pain,
Night is irritated, it is difficult to fall asleep.Once in certain clinic hand-manipulating of needle moxibustion therapy two weeks, the movements such as close one's eyes, frown slightly improve, but bicker
The symptoms such as pain are not alleviated after skew, face stiff tight, neck, ear；Tongue vein is examined：Pale tongue with white fur side is red, thready and moderate pulse.It will be of the invention real
The emplastrum for applying the preparation of example 2 takes appropriate as coin is placed on dressing patch greatly, is affixed on after ear at screen wind scoop, removes after 24 hours, one
Patch is primary, five courses for the treatment of, second day it is medical when, after pasting medicine after readme ear, night pain relief can sleep, be in a cheerful frame of mind,
After being sticked five times, pain disappears.
Case 2
Wu so-and-so, female, 81 years old, Zhangzhou City of Fujian Province Zhangpu County people, on March 20th, 2017 examined, before 2017~2018 years go out
Existing double hip joint pain, more so, pain, need to help double walking stick that could walk round the clock in left side, long-term to alleviate symptom by massage,
Real related doctor diagnoses and treatment is not almost looked for, thinks long campaigns farm work, causes muscle fatigue to be ached, such as rheumathritis
Etc. general diseases, for many years hip joint still long pain, walking lean on double walking stick, left lower extremity is obviously powerless, and left lower extremity compared with
Right lower extremity shortens 3CM or so, can be in and cook, visiting the restroom to complete alone；The end of the year 2017, which were in, leans on crutch and walks, Bu Nengzhan
It is vertical, it lies down in bed, people is needed to nurse, double hip joint and waist, joint of lower extremity are in great pain round the clock, shed tears and keep crying, and double chirobrachialgias are lain
Sleeping sit up needs other people to help, and double-legged toe cannot be bent and stretched, and left leg impotence is soft, long-term cold.Doctor after coherence check, draft for
Femoral head serious change, advising its household is patient's row hip joint three dimensional CT or magnetic resonance imaging as early as possible, to distinguish the weight of illness
Degree is prompted for through Xiamen Haicang hospital nuclear magnetic resonance：Left femoral head aseptic necrosis.Patch prepared by the embodiment of the present invention 1
Cream is placed on 10x20CM dressing patch, is affixed on affected part, is removed after 24 hours, once a day, five courses for the treatment of；Treatment is sticked through above-mentioned
Pain is relieved after method treats a week, and night safely falls asleep, and channel is treated half a year, and patient can stand by walk helper
Walking.
Case 3
Especially so-and-so, female, 58 years old, people from Xiamen City, Fujian Province, on April 21st, 2018 examined, in January, 2018 walking process not
It is careful to fall down, left side Lao bone comminuted fractures of distal, severe pain are caused, sleeping and eating difficulty peace is consolidated in Xiamen First Hospital orthopaedics row gypsum
Determine art, occurs enlargement protrusion at fracture site, the continuous flexion-extension motion of finger-joint, left arm acid after the fixed releasing of three months gypsum
Soft pain is obvious, and outside occurs 6 cun long on elbow joint, and wide 3 cun or so of skin dark region, skin is nervous, and it is abnormal to touch pain.
Blood from overflowing blood vessel after being split for local vascular, infiltrate muscle, fascia etc. tissue carried out by, it is difficult to fall asleep.By the embodiment of the present invention 2
The emplastrum of preparation sticks affected part, removes after 24 hours, once a day, after being sticked once, pain relief；After being sticked seven times,
Swelling and pain disappear, and cooperate acupuncture and moxibustion treatment afterwards, and existing arm function is normal, occurs left ankle-joint nameless gall after one month, step on ground, row
It walks, lies down all in great pain, then primary through bone pain medicine plaster, can walk easily, stick and fully recover afterwards three times.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of bone strengthening ostalgia emplastrum, which is characterized in that the emplastrum includes Moschus, safflower, Radix Salviae Miltiorrhizae, Radix Notoginseng, olibanum, deer
Young pilose antler, radix saposhnikoviae, centipede, thizoma curculiginis, the bletilla striata, the root of Chinese clematis, Caulis Spatholobi, honeycomb, turmeric and borneol.
2. bone strengthening ostalgia emplastrum according to claim 1, which is characterized in that according to parts by weight, the emplastrum includes musk deer
Fragrant 8-12 parts by weight, safflower 45-55 parts by weight, Radix Salviae Miltiorrhizae 45-55 parts by weight, Radix Notoginseng 10-14 parts by weight, olibanum 45-55 weight
Part, pilose antler 15-25 parts by weight, radix saposhnikoviae 55-65 parts by weight, centipede 30-40 parts by weight, thizoma curculiginis 45-55 parts by weight, bletilla striata 45-55
Parts by weight, root of Chinese clematis 75-85 parts by weight, Caulis Spatholobi 95-105 parts by weight, honeycomb 25-35 parts by weight, turmeric 95-105 parts by weight
With borneol 105-110 parts by weight.
3. bone strengthening ostalgia emplastrum according to claim 1 or 2, which is characterized in that according to parts by weight, the emplastrum includes
10 parts by weight of Moschus, 50 parts by weight of safflower, 50 parts by weight of Radix Salviae Miltiorrhizae, 12 parts by weight of Radix Notoginseng, 50 parts by weight of olibanum, 20 weight of pilose antler
Part, windproof 60 parts by weight, 35 parts by weight of centipede, 50 parts by weight of thizoma curculiginis, 50 parts by weight of the bletilla striata, 80 parts by weight of the root of Chinese clematis, Caulis Spatholobi
100 parts by weight, 100 parts by weight of 30 parts by weight of honeycomb, 100 parts by weight of turmeric and borneol.
4. the preparation method of bone strengthening ostalgia emplastrum described in a kind of claim 1-3 any one, which is characterized in that the side
Method includes the following steps：
(1) it is weighed according to the weight of each raw material spare；
(2) weighed each raw material is crushed in addition to borneol, is sieved, obtains traditional Chinese medicine powder；
(3) traditional Chinese medicine powder is impregnated into the water, then extracts, is concentrated under reduced pressure, obtains traditional Chinese medicinal ointment A；
(4) honey will be added in traditional Chinese medicinal ointment A, is boiled, it is cooling, obtain traditional Chinese medicinal ointment B；
(5) weighed borneol is added in traditional Chinese medicinal ointment B, is stirred evenly, is applied on dressing patch, obtain the emplastrum.
5. the preparation method of bone strengthening ostalgia emplastrum according to claim 4, which is characterized in that cross 90-110 in step (2)
Mesh.
6. the preparation method of bone strengthening ostalgia emplastrum according to claim 4, which is characterized in that the mass ratio of traditional Chinese medicine powder and water
It is 1:6-8.
7. the preparation method of bone strengthening ostalgia emplastrum according to claim 4, which is characterized in that the quality of honey and traditional Chinese medicine powder
Than for 4-6:1-3.
8. the preparation method of bone strengthening ostalgia emplastrum according to claim 4, which is characterized in that boil temperature in step (4)
It is 110-120 DEG C, the tanning time is 5-7 hours.
9. the preparation method of bone strengthening ostalgia emplastrum according to claim 8, which is characterized in that boil temperature in step (4)
It is 115 DEG C, the tanning time is 6 hours.
10. the preparation method of bone strengthening ostalgia emplastrum according to claim 4, which is characterized in that step is cooled in (4)
20-25℃。
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| CN101390964A (en) * | 2008-11-10 | 2009-03-25 | 北京天科仁祥医药科技有限公司 | Cataplasm of traditional Chinese medicine for treating hyperosteogeny |
| CN103860998A (en) * | 2013-12-06 | 2014-06-18 | 济南新起点医药科技有限公司 | Plaster for treating osteoproliferation and cervical spondylosis |
| CN106138415A (en) * | 2016-09-08 | 2016-11-23 | 四川聚豪生物科技有限公司 | A kind of Chinese medicine composition of the femur head necrosis caused for a variety of causes |
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2018
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| CN101390964A (en) * | 2008-11-10 | 2009-03-25 | 北京天科仁祥医药科技有限公司 | Cataplasm of traditional Chinese medicine for treating hyperosteogeny |
| CN103860998A (en) * | 2013-12-06 | 2014-06-18 | 济南新起点医药科技有限公司 | Plaster for treating osteoproliferation and cervical spondylosis |
| CN106138415A (en) * | 2016-09-08 | 2016-11-23 | 四川聚豪生物科技有限公司 | A kind of Chinese medicine composition of the femur head necrosis caused for a variety of causes |
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Application publication date: 20181127 |