CN104306851B - Method for preparing medicinal liquor for treating protrusion of lumbar intervertebral disc - Google Patents

Method for preparing medicinal liquor for treating protrusion of lumbar intervertebral disc Download PDF

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CN104306851B
CN104306851B CN201410549663.9A CN201410549663A CN104306851B CN 104306851 B CN104306851 B CN 104306851B CN 201410549663 A CN201410549663 A CN 201410549663A CN 104306851 B CN104306851 B CN 104306851B
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rhizoma
intervertebral disc
lumbar intervertebral
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CN104306851A (en
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周遂记
温自力
周亚光
李中亚
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HENAN SIZHITANG PHARMACEUTICAL Co Ltd
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
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    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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Abstract

The invention provides a method for preparing medicinal liquor for treating protrusion of lumbar intervertebral disc. The method comprises the following steps: grinding prepared kusnezoff monkshood root, galangal, clove and kudzu vine root, steaming, cooling, uniformly mixing with soaked millet, adding mixture of distiller yeast and water, and fermenting in a ceramic container; adding water into the fermented material, carrying out ultrasonic treatment, and filtering to obtain decoction A; grinding spatholobus suberctu, angelica sinensis, polygonatum kingianum, rhizoma cyperi and rhizoma anemarrhenae, adding bacillus natto and sterile water, uniformly mixing, and fermenting in a ceramic container; adding distilled liquor into the fermented product, adding distilled liquor, soaking, heating to 50-60 DEG C, insulating, cooling, and filtering to obtain filtrate to obtain decoction B; mixing the decoction A and the decoction B to obtain decoction C; adding brown granulated sugar, which is fried to coked yellow in an iron pan, into the decoction C, stirring until the brown granulated sugar is completely dissolved, and filtering to obtain the decoction which is the medicinal liquor for treating protrusion of lumbar intervertebral disc. According to the medicinal liquor, drugs play effects by assistance of liquor, monarch, minister, assistant and guide drugs are matched and synergized to play effects of diminishing inflammation, dispelling wind, relieving arthralgia, dredging collaterals to relieve pain, and activating blood circulation to remove stasis.

Description

A kind of preparation method of the medicated wine for treating prolapse of lumbar intervertebral disc
Technical field
The present invention relates to a kind of medicated wine, specifically a kind of preparation method of the medicated wine for treating prolapse of lumbar intervertebral disc.
Background technology
Intervertebral disk hernia is bad sitting posture, stance and length because bad living habit and work habit are caused Phase bends over or heavy physical labour is all pathogenic factor.Prominent intervertebral disc is urged to nerve, just have it is numb, swell, extremity without Power, the symptom of pain.
Clinical statisticses show that it is one of Orthopaedics Clinic illness the most common that lumbar intervertebral disc prominent (de-) goes out disease, is also waist-leg The reason for pain is the most common.History is reviewed, early in Vesalius in 1543 outward appearance of intervertebral disc is just described.20 years 20th century Generation, the Shmorl of Germany has successively delivered the article of 11 relevant intervertebral disc dissections and pathology, has done wide to intervertebral disc Research.1932, Barr proposed that first prolapse of lumbar intervertebral disc is the reason for lumbago and skelalgia is possible.Thereafter, Barr and Mixter be first Propose the concept and Therapeutic Method about prolapse of lumbar intervertebral disc.Hereafter, the basis of disease is gone out to lumbar intervertebral disc prominent (de-) Research is also progressively goed deep into, so as to more improve the effect of clinical diagnosises and the treatment of primary disease.
The content of the invention
The present invention seeks to the deficiency to solve above-mentioned technical problem, there is provided a kind of medicated wine for treating prolapse of lumbar intervertebral disc Preparation method, prepared medicated wine, can wind-dispelling, dehumidifying, dispersing cold for relieving pain, for the treatment of prolapse of lumbar intervertebral disc.
A kind of medicated wine for treating prolapse of lumbar intervertebral disc, the parts by weight of each crude drug of the medicated wine are:Radix Aconiti Kusnezoffii Preparata 20-25 Part, Radix Angelicae Sinensis 8-10 parts, Flos Caryophylli 8-10 parts, Rhizoma Alpiniae Officinarum 8-10 parts, Rhizoma Cyperi 5-8 parts, Caulis Spatholobi 5-8 parts, Radix Puerariae 8-10 parts, Rhizoma Polygonati 5- 8 parts, brown sugar (Saccharum Sinensis Roxb.) 30-33 parts, yellow Semen setariae 50-100 parts and Rhizoma Anemarrhenae 5-8 parts.
The parts by weight of each crude drug of medicated wine of the treatment prolapse of lumbar intervertebral disc are preferably:The each crude drug of the medicated wine Parts by weight be:25 parts of Radix Aconiti Kusnezoffii Preparata, 8.3 parts of Radix Angelicae Sinensis, 8.3 parts of Flos Caryophylli, 8.3 parts of Rhizoma Alpiniae Officinarum, 6 parts of Rhizoma Cyperi, 6 parts of Caulis Spatholobi, Pueraria lobota 5 parts of 8 parts of root, 5 parts of Rhizoma Polygonati, 30 parts of brown sugar (Saccharum Sinensis Roxb.), 80 parts of yellow Semen setariae and the Rhizoma Anemarrhenae.
The preparation method of the medicated wine of the treatment prolapse of lumbar intervertebral disc, comprises the following steps:
Step one, Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Flos Caryophylli, Rhizoma Alpiniae Officinarum, Rhizoma Cyperi, Caulis Spatholobi, Pueraria lobota are taken respectively according to above-mentioned parts by weight Root, Rhizoma Polygonati, brown sugar (Saccharum Sinensis Roxb.), yellow Semen setariae and the Rhizoma Anemarrhenae, it is standby;
Step 2, taken Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and Radix Puerariae are ground into particle diameter be 2.5-5.0mm Chinese medicinal granule; Steam 50-70 minutes at gained Chinese medicinal granule is placed in into 95-100 DEG C, taking-up is cooled to 40-45 DEG C, standby;In taken yellow Semen setariae The water of middle its quality 5-10 times of addition, soaks 5-8 hours, pulls out and drains, standby;
Step 3, will steam after be cooled to 40-45 DEG C of Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and Radix Puerariae Chinese medicinal granule and immersion Mixture is obtained after yellow Semen setariae mix homogeneously afterwards, the distillers yeast and quality 15-20 of its quality 2-3% are added in the resulting mixture Times water, again mix homogeneously be placed in ceramic vessel ferment 2-3 days, take out fermented product;In gained fermented product, its matter is added The water of 15-20 times of amount, ultrasonic Treatment 2-3 hour under 100-200 kHz power filters to obtain medicinal liquid A, standby;
Step 4, the Chinese medicine that taken Caulis Spatholobi, Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Cyperi and the Rhizoma Anemarrhenae are ground into a diameter of 3.0-8.0mm Grain;In gained Chinese medicinal granule, the Bafillus natt of its quality 2-3% and the sterilized water mix homogeneously of quality 2-4% are added, put Ferment 2-3 days in ceramic vessel, take out tunning;In gained tunning, the white of tunning quality 3-6 times is added Wine, immersion 3-4 hours post-heating is subsequently cooled to room temperature to 50-60 DEG C of insulation 2-3 hour, filters to take filtrate, obtains medical liquid B, It is standby;
Step 5, by prepare medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C;Taken brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan fry to Coke yellow, in being added to medicinal liquid C, stirs to being completely dissolved, and stands 24-26 hours, filters, and gained medicinal liquid is as treated between lumbar vertebra The medicated wine of disc protrusion.
Beneficial effect is:
1st, medicated wine of the present invention is formed by the Chinese crude drug compatibility such as Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Rhizoma Alpiniae Officinarum, Flos Caryophylli;Wherein Radix Aconiti Kusnezoffii acrid in the mouth, Hardship, property heat, very toxic, GUIXIN liver spleen channel has the effect of antalgic, expelling wind and removing dampness, to anemofrigid-damp arthralgia, has good effect, is monarch drug; Radix Angelicae Sinensis sweet in the mouth is pungent, warm in nature, the work(with soothing liver-QI of enriching blood, promoting blood circulation and stopping pain, is ministerial drug;Rhizoma Alpiniae Officinarum acrid in the mouth, property heat, returns spleen stomach can Warming spleen and stomach for dispelling cold pain relieving, is adjuvant drug;Flos Caryophylli acrid in the mouth, warm in nature, returns spleen lung meridian has warming middle-JIAO to send down the adverse QI, effect of reinforcing the kidney and supporting YANG.It is in addition white Wine, warming the meridian and activating blood circulation, Dredging collaterals to dissipate cold.Wine assisting drug, wine helps medicine gesture, and four medicine compatibilities, monarch is mutually coordinated, antiinflammatory, wind-dispelling a surname Numbness, removing obstruction in the collateral to relieve pain, promoting blood circulation Eradicates blood stasis and smoothing collaterals, especially have preferable therapeutic effect to treating prolapse of lumbar intervertebral disc;Using treatment The medicated wine wine treatment of prolapse of lumbar intervertebral disc can reach satisfied effect;The medicated wine treatment waist of prolapse of lumbar intervertebral disc is treated simultaneously Intervertebral disc prolapse has convenient, safe, cheap, eutherapeutic feature.
2nd, the present invention is fermented Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and Radix Puerariae Chinese medicinal granule using distillers yeast in ceramic vessel, can be by The active ingredient beneficial to treatment prolapse of lumbar intervertebral disc in Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and Radix Puerariae is separated out, and follow-up natto bud More preferable therapeutic effect is reached after the medicinal liquid mixing of the Caulis Spatholobi of spore bacillus fermentation, Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Cyperi and the Rhizoma Anemarrhenae;Natto bud Spore bacillus is that in the middle of various beneficial bacterias, preferably can go directly one of strain of small intestinal to environment resistance, it is oral after can change human body Intestinal flora is ecological, helps digest function normalization, so that defecation is smooth, maintains body physiological environmental protection.Acid can be produced, is adjusted Intestinal microbial population, enhancing animal cell immunity is put should;Using bacillus natto to ferment Caulis Spatholobi, Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Cyperi and know Mother, in addition to it medicine can to greatest extent be played into its effect, can also adjust body immunity, improve the utilization of medicine Rate.
Specific embodiment
A kind of medicated wine for treating prolapse of lumbar intervertebral disc, the parts by weight of each crude drug of the medicated wine are:Radix Aconiti Kusnezoffii Preparata 20-25 Part, Radix Angelicae Sinensis 8-10 parts, Flos Caryophylli 8-10 parts, Rhizoma Alpiniae Officinarum 8-10 parts, Rhizoma Cyperi 5-8 parts, Caulis Spatholobi 5-8 parts, Radix Puerariae 8-10 parts, Rhizoma Polygonati 5- 8 parts, brown sugar (Saccharum Sinensis Roxb.) 30-33 parts, yellow Semen setariae 50-100 parts and Rhizoma Anemarrhenae 5-8 parts.
The parts by weight of each crude drug of medicated wine of the treatment prolapse of lumbar intervertebral disc are preferably:The each crude drug of the medicated wine Parts by weight be:25 parts of Radix Aconiti Kusnezoffii Preparata, 8.3 parts of Radix Angelicae Sinensis, 8.3 parts of Flos Caryophylli, 8.3 parts of Rhizoma Alpiniae Officinarum, 6 parts of Rhizoma Cyperi, 6 parts of Caulis Spatholobi, Pueraria lobota 5 parts of 8 parts of root, 5 parts of Rhizoma Polygonati, 30 parts of brown sugar (Saccharum Sinensis Roxb.), 80 parts of yellow Semen setariae and the Rhizoma Anemarrhenae.
The preparation method of the medicated wine of the treatment prolapse of lumbar intervertebral disc, comprises the following steps:
Step one, take Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Flos Caryophylli, Rhizoma Alpiniae Officinarum, Rhizoma Cyperi 5-8 parts, Sanguis Gallus domesticus respectively according to above-mentioned parts by weight Rattan, Radix Puerariae, Rhizoma Polygonati, brown sugar (Saccharum Sinensis Roxb.), yellow Semen setariae and the Rhizoma Anemarrhenae, it is standby;
Step 2, taken Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and Radix Puerariae are ground into particle diameter be 2.5-5.0mm Chinese medicinal granule; Steam 50-70 minutes at gained Chinese medicinal granule is placed in into 95-100 DEG C, taking-up is cooled to 40-45 DEG C, standby;In taken yellow Semen setariae The water of middle its quality 5-10 times of addition, soaks 5-8 hours, pulls out and drains, standby;
Step 3, will steam after be cooled to 40-45 DEG C of Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and Radix Puerariae Chinese medicinal granule and immersion Mixture is obtained after yellow Semen setariae mix homogeneously afterwards, the distillers yeast and quality 15-20 of its quality 2-3% are added in the resulting mixture Times water, again mix homogeneously be placed in ceramic vessel ferment 2-3 days, take out fermented product;In gained fermented product, its matter is added The water of 15-20 times of amount, ultrasonic Treatment 2-3 hour under 100-200 kHz power filters to obtain medicinal liquid A, standby;
Step 4, the Chinese medicine that taken Caulis Spatholobi, Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Cyperi and the Rhizoma Anemarrhenae are ground into a diameter of 3.0-8.0mm Grain;In gained Chinese medicinal granule, the Bafillus natt of its quality 2-3% and the sterilized water mix homogeneously of quality 2-4% are added, put Ferment 2-3 days in ceramic vessel, take out tunning;In gained tunning, the white of tunning quality 3-6 times is added Wine, immersion 3-4 hours post-heating is subsequently cooled to room temperature to 50-60 DEG C of insulation 2-3 hour, filters to take filtrate, obtains medical liquid B, It is standby;
Step 5, by prepare medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C;Taken brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan fry to Coke yellow, in being added to medicinal liquid C, stirs to being completely dissolved, and stands 24-26 hours, filters, and gained medicinal liquid is as treated between lumbar vertebra The medicated wine of disc protrusion.
Embodiment 1
A kind of medicated wine for treating prolapse of lumbar intervertebral disc, the parts by weight of each crude drug of the medicated wine are:25 parts of Radix Aconiti Kusnezoffii Preparata, 8.3 parts of Radix Angelicae Sinensis, 8.3 parts of Flos Caryophylli, 8.3 parts of Rhizoma Alpiniae Officinarum, 6 parts of Rhizoma Cyperi, 6 parts of Caulis Spatholobi, 8 parts of Radix Puerariae, 5 parts of Rhizoma Polygonati, 30 parts of brown sugar (Saccharum Sinensis Roxb.), 5 parts of 80 parts of yellow Semen setariae and the Rhizoma Anemarrhenae.
The preparation method of the medicated wine of the treatment prolapse of lumbar intervertebral disc, comprises the following steps:
Step one, Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Flos Caryophylli, Rhizoma Alpiniae Officinarum, Rhizoma Cyperi, Caulis Spatholobi, Pueraria lobota are taken respectively according to above-mentioned parts by weight Root, Rhizoma Polygonati, brown sugar (Saccharum Sinensis Roxb.), yellow Semen setariae and the Rhizoma Anemarrhenae, it is standby;
Step 2, taken Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and Radix Puerariae are ground into particle diameter be 2.5mm Chinese medicinal granule;By institute Chinese medicinal granule be placed in 95 DEG C at steam 50 minutes, taking-up is cooled to 40 DEG C, standby;Its quality 5 is added in taken yellow Semen setariae Water again, soaks 5 hours, pulls out and drains, standby;
Step 3, will steam after be cooled to 40 DEG C of Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and Radix Puerariae Chinese medicinal granule and immersion after Mixture is obtained after yellow Semen setariae mix homogeneously, the distillers yeast of its quality 2% and the water of 15 times of quality are added in the resulting mixture, then Secondary mix homogeneously is placed in ceramic vessel and ferments 2 days, takes out fermented product;In gained fermented product, the water of 15 times of its quality is added, Ultrasonic Treatment 2-3 hour under 100 kHz power, filters to obtain medicinal liquid A, standby;
Step 4, the Chinese medicinal granule that taken Caulis Spatholobi, Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Cyperi and the Rhizoma Anemarrhenae are ground into a diameter of 3.0mm; In gained Chinese medicinal granule, the Bafillus natt of its quality 2% and the sterilized water mix homogeneously of quality 2% are added, be placed in ceramics Ferment 2 days in container, take out tunning;In gained tunning, the Chinese liquor of 3 times of tunning quality is added, immersion 3 is little When post-heating to 50 DEG C be incubated 2 hours, be subsequently cooled to room temperature, filter to take filtrate, obtain medical liquid B, it is standby;
Step 5, by prepare medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C;Taken brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan fry to Coke yellow, in being added to medicinal liquid C, stirs to being completely dissolved, and stands 24 hours, filters, and gained medicinal liquid as treats lumbar intervertebral disc The medicated wine of herniation.
Embodiment 2
A kind of medicated wine for treating prolapse of lumbar intervertebral disc, the parts by weight of each crude drug of the medicated wine are:20 parts of Radix Aconiti Kusnezoffii Preparata, 8 parts of Radix Angelicae Sinensis, 8 parts of Flos Caryophylli, 8 parts of Rhizoma Alpiniae Officinarum, 5 parts of Rhizoma Cyperi, 5 parts of Caulis Spatholobi, 9 parts of Radix Puerariae, 6 parts of Rhizoma Polygonati, 32 parts of brown sugar (Saccharum Sinensis Roxb.), yellow Semen setariae 50 parts and 7 parts of the Rhizoma Anemarrhenae.
The preparation method of the medicated wine of the treatment prolapse of lumbar intervertebral disc, comprises the following steps:
Step one, Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Flos Caryophylli, Rhizoma Alpiniae Officinarum, Rhizoma Cyperi, Caulis Spatholobi, Pueraria lobota are taken respectively according to above-mentioned parts by weight Root, Rhizoma Polygonati, brown sugar (Saccharum Sinensis Roxb.), yellow Semen setariae and the Rhizoma Anemarrhenae, it is standby;
Step 2, taken Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and Radix Puerariae are ground into particle diameter be 5.0mm Chinese medicinal granule;By institute Chinese medicinal granule be placed in 100 DEG C at steam 70 minutes, taking-up is cooled to 45 DEG C, standby;Its quality is added in taken yellow Semen setariae 10 times of water, soaks 8 hours, pulls out and drains, standby;
Step 3, will steam after be cooled to 45 DEG C of Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and Radix Puerariae Chinese medicinal granule and immersion after Mixture is obtained after yellow Semen setariae mix homogeneously, the distillers yeast of its quality 2-3% and the water of 20 times of quality is added in the resulting mixture, Again mix homogeneously is placed in ceramic vessel and ferments 3 days, takes out fermented product;In gained fermented product, 20 times of its quality is added Water, ultrasonic Treatment 2-3 hour under 200 kHz power filters to obtain medicinal liquid A, standby;
Step 4, the Chinese medicinal granule that taken Caulis Spatholobi, Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Cyperi and the Rhizoma Anemarrhenae are ground into a diameter of 8.0mm; In gained Chinese medicinal granule, the Bafillus natt of its quality 3% and the sterilized water mix homogeneously of quality 4% are added, be placed in ceramics Ferment 3 days in container, take out tunning;In gained tunning, the Chinese liquor of 6 times of tunning quality is added, immersion 4 is little When post-heating to 60 DEG C be incubated 3 hours, be subsequently cooled to room temperature, filter to take filtrate, obtain medical liquid B, it is standby;
Step 5, by prepare medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C;Taken brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan fry to Coke yellow, in being added to medicinal liquid C, stirs to being completely dissolved, and stands 26 hours, filters, and gained medicinal liquid as treats lumbar intervertebral disc The medicated wine of herniation.
Embodiment 3
A kind of medicated wine for treating prolapse of lumbar intervertebral disc, the parts by weight of each crude drug of the medicated wine are:25 parts of Radix Aconiti Kusnezoffii Preparata, 10 parts of Radix Angelicae Sinensis, 10 parts of Flos Caryophylli, 10 parts of Rhizoma Alpiniae Officinarum, 8 parts of Rhizoma Cyperi, 8 parts of Caulis Spatholobi, 10 parts of Radix Puerariae, 8 parts of Rhizoma Polygonati, 33 parts of brown sugar (Saccharum Sinensis Roxb.), Huang 8 parts of 100 parts of Semen setariae and the Rhizoma Anemarrhenae.
The preparation method of the medicated wine of the treatment prolapse of lumbar intervertebral disc, comprises the following steps:
Step one, Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Flos Caryophylli, Rhizoma Alpiniae Officinarum, Rhizoma Cyperi, Caulis Spatholobi, Pueraria lobota are taken respectively according to above-mentioned parts by weight Root, Rhizoma Polygonati, brown sugar (Saccharum Sinensis Roxb.), yellow Semen setariae and the Rhizoma Anemarrhenae, it is standby;
Step 2, taken Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and Radix Puerariae are ground into particle diameter be 3.5mm Chinese medicinal granule;By institute Chinese medicinal granule be placed in 98 DEG C at steam 60 minutes, taking-up is cooled to 42 DEG C, standby;Its quality 8 is added in taken yellow Semen setariae Water again, soaks 7 hours, pulls out and drains, standby;
Step 3, will steam after be cooled to 42 DEG C of Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and Radix Puerariae Chinese medicinal granule and immersion after Mixture is obtained after yellow Semen setariae mix homogeneously, the distillers yeast of its quality 2.5% and the water of 18 times of quality is added in the resulting mixture, Again mix homogeneously is placed in ceramic vessel and ferments 2 days, takes out fermented product;In gained fermented product, 18 times of its quality is added Water, ultrasonic Treatment 2-3 hour under 150 kHz power filters to obtain medicinal liquid A, standby;
Step 4, the Chinese medicinal granule that taken Caulis Spatholobi, Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Cyperi and the Rhizoma Anemarrhenae are ground into a diameter of 3.5mm; In gained Chinese medicinal granule, the Bafillus natt of its quality 2.5% and the sterilized water mix homogeneously of quality 3% are added, be placed in pottery Ferment 2 days in porcelain container, take out tunning;In gained tunning, the Chinese liquor of 5 times of tunning quality, immersion 3 are added Hour post-heating to 55 DEG C are incubated 2 hours, are subsequently cooled to room temperature, filter to take filtrate, obtain medical liquid B, standby;
Step 5, by prepare medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C;Taken brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan fry to Coke yellow, in being added to medicinal liquid C, stirs to being completely dissolved, and stands 25 hours, filters, and gained medicinal liquid as treats lumbar intervertebral disc The medicated wine of herniation.
First, clinical testing data
1st, experimental subject:The patient 300 of prolapse of lumbar intervertebral disc is suffered from inspection, and wherein lumbago symptom is lighter, it is prominent Type mainly take place frequently lumbago or increase and with lower limb rediating pain patient 60, prolapsus sequestered lumbago take place frequently, increase at nightfall, generally With the patient 110 of serious lower limb rediating pain, lumbago takes place frequently, and increases at nightfall, generally with serious lower limb rediating pain person 140 Name;There is cauda equina nerve symptom in some patientss, or sensory disturbance and muscular strength decline.
2nd, Therapeutic Method:The medicated wine of oral medication prolapse of lumbar intervertebral disc, three times a day, each 5-15 milliliters, (medicine) being taken before meal With.It is daily 2-3 time simultaneously with the appropriate affected part of exterior coating of the medicated wine;It is within 7 days 1 course for the treatment of.
3rd, evaluation criterion is treated:
Cure:CT shows the healing of lumbar vertebra vertebra disk annulus fibrosus portion, and top layer is complete, and vertebral pulp is good with intraspinal tube physiological level position Good clear, surface is smooth, and pain disappears;
It is effective:Anular disruption degree is significantly taken on a new look between lumbar vertebra vertebra disk, and part is healed, and vertebral pulp is dashed forward different to canalis spinalis phenomenon Degree is alleviated, and posterior longitudinal ligament covers complete, and surface is more smooth, and lumbago symptom and lower limb rediating pain symptom disappear substantially;
Effectively:Meet healing or effective standard.
It is invalid:CT shows lumbar intervertebral disc without significant changes.
4th, therapeutic effect:300 patients that the present invention is treated, wherein cure patients with lumbar disc herniation 195, it is effective 72, total effective rate reaches 89%;As a result the medicated wine of present invention treatment prolapse of lumbar intervertebral disc is shown, formula and prescription is reasonable, to waist Intervertebral disc prolapse is evident in efficacy.
2nd, model case:
1st, poplar, man, 50 years old, lumbago four months(Increase one month), CT shows prolapse of lumbar intervertebral disc, middle Lumbago when being admitted to hospital Shape is lighter, and protruding type mainly takes place frequently and lumbago or increases and with lower limb rediating pain;The medicated wine of oral medication prolapse of lumbar intervertebral disc, often Day three times, each 5-15 milliliters, (medicine) being taken before meal is used.And with the appropriate affected part of exterior coating of medicated wine of prolapse of lumbar intervertebral disc is treated, daily 2-3 time;Continuously treat two courses for the treatment of;Lumbago remission, after three courses for the treatment of of continuous treatment, lumbago disappears, and continues clothes to five courses for the treatment of, multiple CT joint of lumbar vertebra is looked into, vertebra disk fibrous ring top layer is complete, and physiological level position is well clear, so far without recurrence.
2nd, Sun, female, 43 years old, lumbago more than 2 years(Increase three months), at nightfall and overwork postemphasis is especially apparent, lower limb fiber crops Wooden pain, action of bending over and go down on one's knees slightly is limited, and CT examination shows prolapse of lumbar intervertebral disc, oral medication prolapse of lumbar intervertebral disc Medicated wine, three times a day, each 5-15 milliliters, (medicine) being taken before meal is used.And applied outward in right amount with the medicated wine for the treatment of prolapse of lumbar intervertebral disc and suffered from Place, it is daily 2-3 time;Continuously treat two courses for the treatment of;Lumbago remission, after three courses for the treatment of of continuous treatment, lumbago disappears, continuously continuous to control Five courses for the treatment of are treated, check CT shows that intervertebral Anular disruption degree is greatly improved, and portion healing, vertebral pulp is longitudinally projecting slightly Retraction, posterior longitudinal ligament covers complete, and surface is smooth, and miscellaneous function is taken exercise, freely flexibly.Continuous treatment is consolidated to nine courses for the treatment of Gu, advise wind sheltering after its discharge to tremble with fear, careful work, so far without recurrence.
3rd, willow, man, 65 years old, the lumbago that takes place frequently 7 years, double lower limb was numb, and thigh lateral muscle group and gluteus maximus have an intense pain, Autonomous Disability, increased before two months, and the CT that is admitted to hospital shows prolapse of lumbar intervertebral disc, the medicine of oral medication prolapse of lumbar intervertebral disc Wine, three times a day, each 5-15 milliliters, (medicine) being taken before meal is used.And with treatment prolapse of lumbar intervertebral disc the appropriate affected part of exterior coating of medicated wine, It is daily 2-3 time;Continuously treat two courses for the treatment of;Lumbago remission, after three courses for the treatment of of continuous treatment, lumbago disappears, continuous continuous treatment Seven courses for the treatment of, check CT shows that intervertebral Anular disruption degree is greatly improved, portion healing, and vertebral pulp is longitudinally projecting to be slightly had back Contracting, posterior longitudinal ligament covers complete, and surface is smooth, and miscellaneous function is taken exercise, freely flexibly.Continuous treatment is consolidated to nine courses for the treatment of, Wind sheltering after its discharge is advised to tremble with fear, careful work, uncomfortable follow-up, so far without recurrence.
Bafillus natt of the present invention, is common Bafillus natt strain, can be commercially available by market.

Claims (1)

1. a kind of preparation method of the medicated wine for treating prolapse of lumbar intervertebral disc, it is characterised in that:Comprise the following steps:
Step one, take 20 parts of Radix Aconiti Kusnezoffii Preparata, 8 parts of Radix Angelicae Sinensis, 8 parts of Flos Caryophylli, 8 parts of Rhizoma Alpiniae Officinarum, 5 parts of Rhizoma Cyperi, chicken respectively according to parts by weight 7 parts of 5 parts of Caulis seu Radix Schisandrae Henryi, 9 parts of Radix Puerariae, 6 parts of Rhizoma Polygonati, 32 parts of brown sugar (Saccharum Sinensis Roxb.), 50 parts of yellow Semen setariae and the Rhizoma Anemarrhenae, it is standby;
Step 2, taken Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and Radix Puerariae are ground into particle diameter be 2.5-5.0mm Chinese medicinal granule;By institute Chinese medicinal granule be placed in 95-100 DEG C at steam 50-70 minutes, taking-up is cooled to 40-45 DEG C, standby;Add in taken yellow Semen setariae Enter the water of its quality 5-10 times, soak 5-8 hours, pull out and drain, it is standby;
Step 3, will steam after be cooled to 40-45 DEG C of Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and Radix Puerariae Chinese medicinal granule and immersion after Mixture is obtained after yellow Semen setariae mix homogeneously, the distillers yeast of its quality 2-3% and 15-20 times of water are added in the resulting mixture, then Secondary mix homogeneously is placed in ceramic vessel and ferments 2-3 days, takes out fermented product;In gained fermented product, its quality 15-20 times is added Water, ultrasonic Treatment 2-3 hour under 100-200 kHz power filters to obtain medicinal liquid A, standby;
Step 4, the Chinese medicinal granule that taken Caulis Spatholobi, Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Cyperi and the Rhizoma Anemarrhenae are ground into a diameter of 3.0-8.0mm; In gained Chinese medicinal granule, the Bafillus natt of its quality 2-3% and the sterilized water mix homogeneously of 2-4% are added, be placed in ceramics Ferment 2-3 days in container, take out tunning;In gained tunning, the Chinese liquor of tunning quality 3-6 times, leaching are added Bubble 3-4 hours post-heating is subsequently cooled to room temperature to 50-60 DEG C of insulation 2-3 hour, filters to take filtrate, obtains medical liquid B, standby;
Step 5, gained medicinal liquid A and medical liquid B are mixed, obtain medicinal liquid C;Taken brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan and is fried to coke yellow, In being added to medicinal liquid C, stir to being completely dissolved, stand 24-26 hours, filter, gained medicinal liquid prepares treatment lumbar intervertebral disc The medicated wine of herniation.
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