CN111437308A - Arthralgia-relieving, bone-nourishing and fumigating application formula and application thereof - Google Patents

Abstract

The invention belongs to the technical field of medicines, and particularly relates to a dredging, bone-nourishing and fumigating application formula which is prepared from the following traditional Chinese medicine raw materials in parts by weight: 150 portions of artemisia leaf, 150 portions of eucommia bark, 150 portions of ramulus Uncariae cum uncis, 150 portions of lycopodium clavatum, 150 portions of tripterygium wilfordii, 150 portions of speranskia tuberculata, 150 portions of Chinese pine knot, 150 portions of clove, 150 portions of Acer buergerianum, 150 portions of Alangium platanifolium, 150 portions of pyrum glauca, 100 portions of Sargentodoxa cuneata, 100 portions of akebia stem, 200 portions of Panax notoginseng leaf, 100 portions of Alangium platyphylla, 150 portions of suberect spatholobus stem, 250 portions of pawpaw, 100 portions of piper perny, and 200 portions of parasitic grass. Has the total effects of expelling wind and cold, removing dampness, dredging meridian passage, clearing away heat and toxic materials, relieving swelling, dispersing pathogen accumulation, warming stomach, regulating stomach function, and invigorating stomach. The main treatment is as follows: rheumatic bone diseases (rheumatic osteoarthritis, rheumatoid diseases, ankylosing spondylitis, femoral head necrosis, lumbar disc herniation (bulging), gout, psoriasis skin diseases), degenerative osteoarthropathy, etc. Its effective rate is up to 93.4%.

Description

Arthralgia-relieving, bone-nourishing and fumigating application formula and application thereof

Technical Field

The invention belongs to the technical field of medicines, and particularly relates to a dredging and bone-nourishing fumigation application formula and a preparation method thereof.

Background

Arthralgia is the condition of obstruction of qi. In traditional Chinese medicine, arthralgia syndrome refers to a type of disease which is mainly caused by wind, cold, dampness, heat and the like on the body surface and meridians and mainly caused by soreness, numbness, heaviness, difficulty in flexion and extension of limbs and joints, or even swelling and burning of joints.

The range of limb paralysis is wide, and the limb paralysis is mainly divided into wind arthralgia, damp arthralgia, heat arthralgia and cold arthralgia. The arthralgia due to wind-cold is characterized in that pain can wander around and cannot be fixed at a certain part to cause pain; damp arthralgia is well known as rheumatism and rheumatoid diseases, joint pain and even swelling, and aggravation in rainy days; the pyretic arthralgia is characterized in that when the joint is painful, the local part of the joint is red and swollen, has burning sensation and is accompanied with fever; the arthralgia aggravated by cold is more severe than other pains, and the pain is aggravated when the patient is in cold, fixed in pain point, not hot and not red.

At present, the traditional Chinese medicine is used for treating rheumatism bone diseases (generally called as arthralgia syndrome in traditional Chinese medicine), common rheumatism bone diseases comprise rheumatic osteoarthritis, rheumatoid diseases, ankylosing spondylitis, femoral head necrosis, lumbar disc herniation (swelling), gout, psoriasis skin diseases, degenerative osteoarthropathy and the like. The western medicine mainly uses hormone medicines and anti-inflammatory analgesic medicines, has large side effect, damages various organs and systems of a human body to different degrees, can not consolidate the curative effect and has high recurrence rate. The traditional Chinese medicine oral administration effect is not good enough, and the medicine taking time is long, so that the traditional Chinese medicine oral administration is difficult for patients to accept.

Patent CN106421534A discloses a traditional Chinese medicine composition for treating rheumatoid arthritis, which is characterized by being prepared from the following components in parts by weight: 0.2 to 5 portions of schizophragma integrifolium, 0.2 to 5 portions of winged sweetgum, 0.2 to 5 portions of winged yam rhizome, 0.2 to 5 portions of three-leaf lysimachia herb, 0.2 to 5 portions of Wuzhua fig, 0.2 to 5 portions of triangle wind, 0.2 to 5 portions of Chinese alangium, 0.2 to 5 portions of eighteen symptom, 0.2 to 5 portions of red fisheye, 0.2 to 5 portions of semiliquidambar cathayensis, 0.2 to 5 portions of artemisia sieboldii, 0.2 to 5 portions of arborvitae, 0.2 to 5 portions of yellow azalea, 0.2 to 5 portions of labrum, 0.2 to 5 portions of hollyhock, 0.2 to 5 portions of Chinese tamarisk, 0.2 to 5 portions of Chinese silkvine, 0.2 to 5 portions of common clubmoss herb, 0.2 to 5 portions of peony, 0.2 to 5 portions of Wuxiangpi, 0.2 to 5 portions of Chinese fevervine, 0.2 to 5 portions of Japanese sweetflag, 0.2 to 5 portions of Japanese stephania, 0.5 portions of Japanese stephania, 0.2 to 5 portions of Japanese stephania, 0.5 portions of Japanese, 0.2-5 parts of caulis gaultheriae yunnanensis, 0.2-5 parts of leopard, 0.2-5 parts of Chinese yam, 0.2-5 parts of medicated leaven, 0.2-5 parts of caulis spatholobi, 0.2-5 parts of kadsura pepper stem, 0.2-5 parts of cassia twig, 0.2-5 parts of liquorice, 5-7 parts of horse bone, 5-7 parts of falsework bone, 2-6 parts of bighead atractylodes rhizome, 2-6 parts of coix seed, 2-6 parts of poria cocos and 2-6 parts of dried orange peel. The composition is in form of oral preparation, and can be made into pill for treating rheumatoid arthritis. The medicine has a large prescription, consists of more than forty-five medicines, and is prepared from schizophragma integrifolia, winged maple, winged yam rhizome, three-money-tree, Wuzhua (root of Chinese Parmelia), triangle wind, Chinese alangium, eighteen symptoms, red fish eyes, semiliquidambar cathayensis, artemisia sieboldii, yellow azalea, labyrinthica, hollyhock, salix chebula, alkali blossom, clerodendron bungei, sargentgloryvine stem, philippine flemingia root, diatrizoate, leopard, horse bone and falsewort bone which are all common medicinal materials, and the medicines are not easy to combine and are inconvenient to prepare. And the medicine taking time is long, and the medicine is not easy to be accepted by patients.

Aiming at the conditions that the clinical rheumatism and osteopathia (traditional Chinese medicine arthralgia syndrome) in medicine has high morbidity, has great influence on human health and life, and other treatment methods have poor curative effect and great side effect, the problem that the traditional Chinese medicine which is not orally taken and has good efficacy is needed to be solved urgently is searched.

Disclosure of Invention

In order to solve the technical problems, the invention provides a dredging and bone-nourishing fumigation application formula and a preparation method thereof.

The invention is realized by the following technical scheme:

the Chinese medicinal composition for treating arthralgia, nourishing bones and fumigating consists of the following Chinese medicinal raw materials in parts by weight:

150 portions of artemisia leaf, 150 portions of eucommia bark, 150 portions of ramulus Uncariae cum uncis, 150 portions of lycopodium clavatum, 150 portions of tripterygium wilfordii, 150 portions of speranskia tuberculata, 150 portions of Chinese pine knot, 150 portions of clove, 150 portions of Acer buergerianum, 150 portions of Alangium platanifolium, 150 portions of pyrum glauca, 100 portions of Sargentodoxa cuneata, 100 portions of akebia stem, 200 portions of Panax notoginseng leaf, 100 portions of Alangium platyphylla, 150 portions of suberect spatholobus stem, 250 portions of pawpaw, 100 portions of piper perny, and 200 portions of parasitic grass.

Preferably, the dredging, bone-nourishing and fumigating application formula consists of the following traditional Chinese medicine raw materials in parts by weight:

180 portions of artemisia leaf, 180 portions of eucommia bark, 180 portions of ramulus Uncariae cum uncis, 220 portions of lycopodium clavatum, 180 portions of tripterygium wilfordii, 180 portions of speranskia tuberculata, 180 portions of Chinese pine knot, 180 portions of clove, 180 portions of Acer buergerianum, 180 portions of Alangium platanifolium, 180 portions of pyrum glauca, 130 portions of Sargentodoxa cuneata, 130 portions of akebia stem, 130 portions of notoginseng leaf, 130 portions of Alangium platyphylla, 170 portions of spatholobus stem, 180 portions of pawpaw, 220 portions of piper longum, 130 portions of piper longum and 130 portions of parasitic grass.

More preferably, the dredging, bone-nourishing and fumigating application formula comprises the following traditional Chinese medicine raw materials in parts by weight:

200 parts of folium artemisiae argyi, 200 parts of eucommia ulmoides, 200 parts of double-hook, 200 parts of lycopodium clavatum, 200 parts of tripterygium wilfordii, 200 parts of garden balsam stem, 200 parts of Chinese pine node, 200 parts of clove flower, 200 parts of maple, 200 parts of Chinese alangium, 200 parts of herba pyrrosiae, 150 parts of sargentgloryvine stem, 150 parts of akebia stem, 150 parts of pseudo-ginseng leaf, 150 parts of climbing entada, 200 parts of caulis spatholobi, 200 parts of pawpaw, 150 parts of long pepper and 150 parts of parasitic grass.

The Chinese medicine is an external preparation in dosage form of the fumigation application formula for dredging the arthralgia and nourishing the bone.

The application of the arthralgia-relieving and bone-nourishing fumigation application formula in preparation of a medicine for treating rheumatoid bone diseases.

The application of the arthralgia-relieving and bone-nourishing fumigation application formula in preparing a medicine for treating rheumatic osteoarthritis.

The application of the arthralgia-relieving and bone-nourishing fumigation application formula in preparation of medicines for treating rheumatoid arthritis.

The application of the arthralgia-relieving and bone-nourishing fumigation application formula in preparation of a medicament for treating ankylosing spondylitis.

The application of the arthralgia-relieving and bone-nourishing fumigation application formula in preparing a medicine for treating femoral head necrosis.

The application of the arthralgia-relieving and bone-nourishing fumigation application formula in preparation of a medicine for treating gout.

The application of the dredging and bone-nourishing fumigation application formula in preparation of a medicine for treating psoriasis skin diseases.

The application of the dredging, bone-nourishing and fumigating prescription in preparing the medicament for treating the connective tissue disease.

The application of the arthralgia-relieving, bone-nourishing and fumigation application formula in preparation of medicines for treating scleroderma.

The application of the arthralgia-relieving, bone-nourishing and fumigation-applying formula in preparation of a medicine for treating cervical spondylosis.

The application of the arthralgia-relieving, bone-nourishing and fumigation-applying formula in preparation of a medicament for treating lumbar vertebra diseases.

The application of the dredging and bone-nourishing fumigation application formula in preparing the medicine for treating eczema.

The application of the obstruction-freeing bone-nourishing fumigation application formula in preparing a medicine for treating acne.

The application of the dredging and bone-nourishing fumigation application formula in preparation of a medicine for treating Raynaud's syndrome.

The application of the arthralgia-relieving and bone-nourishing fumigation application formula in preparation of a medicine for treating myasthenia gravis.

The application of the arthralgia-relieving and bone-nourishing fumigation application formula in preparation of medicines for treating radiculitis is provided.

The application method of the obstruction-freeing bone-nourishing fumigation application formula comprises the following steps: soaking in warm water, decocting (the patient is on a fumigation bed at 38-42 ℃ for 30 minutes), smearing, hot compressing and bathing.

In the obstruction-freeing bone-nourishing fumigation application formula,

double hook: and (3) synonymy: then collude the common name: extracts from uncaria (Chinese herbal medicine roll P427) source: is stem branch with hook of Uncaria rhynchophylla, Uncaria sinica and Uncaria macrophylla of Rubiaceae. Medicine property: sweet taste and cold nature. Enter the heat channel. The functions and indications are as follows: extinguish wind and stop spasm, clear heat and pacify liver. It can be used for treating infantile convulsion, night cry, excessive heat, wind stirring, eclampsia, dizziness, and headache. Pharmacology: 1. effect on the cardiovascular system: lowering blood pressure, treating cardiac diseases, treating myocardial electrophysiology, and resisting arrhythmia; 2. inhibiting platelet aggregation and antithrombotic formation; 3. sedative, antiepileptic and anticonvulsant effects; 4. protective action on cerebral ischemia and hypoxia; 5. effect on smooth muscle.

The extract of Chinese materia medica seedling medicated roll P36 is derived from stem and leaf of Hedera sinensis belonging to Araliaceae. Medicine property: bitter taste and cold nature. Enter the heat channel. The functions and indications are as follows: dispel wind and remove toxicity, activate blood and alleviate pain, resolve swelling and alleviate pain. Can be used for treating rheumatalgia, paralysis, numbness, hematemesis, hemoptysis, epistaxis, hematochezia, skin pruritus, eczema, traumatic injury, and innominate toxic swelling.

Extracting the medicine property of akebia stem (Chinese herbal medicine seedling medicated roll P25): sweet taste and cold nature. Enter the heat channel. The functions and the main treatment: soothing liver and harmonizing stomach, promoting blood circulation to arrest pain, softening hardness to dissipate stagnation. It is mainly used for treating abdominal pain, hypochondriac swelling and pain, scrotum contraction, hernia pain, amenorrhea, dysmenorrhea, goiter, scrofula. Pharmacology: has antitumor effect.

The source of the Alangium platanifolium extract (Chinese herbal seedling medicated roll P26): is the root, fibrous root and root bark of Alangium platanifolium of Alangiaceae.

Medicine property: pungent and numb taste, hot; is toxic. Entering the cold channel. The functions and indications are as follows: dispelling pathogenic wind and removing dampness, relieving rigidity of muscles and activating collaterals, removing blood stasis and relieving pain, and can be used for treating rheumatalgia, limbs anesthesia, and traumatic injury. Pharmacology: 1. muscle relaxation effect; 2. effects on the respiratory system; 3. effects on the cardiovascular system; 4. effect on smooth muscle.

The herba Polygoni Ciliinerve is flower of herba Polygoni Ciliinerve of Labiatae. Latin plant name: colles coc cinea wall. var. mollis (Schlecht.) Prain [ c. The efficacy is as follows: clearing liver and improving vision. The functional indications are as follows: it is mainly indicated for liver heat with conjunctival congestion and nebula. The flowers of the torch, the names of the plants, from the west to the middle of Yunnan, the southeast of Tibet; grows in a litsea slope and irrigation clusters, is rarely seen in dense forests, and has an altitude of 1450- & 3000 meters. The flower is like fire after the Yunnan Bai Huiguan festival, so the Huoluan flower can be viewed and appreciated, and the human medicine is used for replacing butterflybush flower for improving eyesight. The alternative name is as follows: flos Buddlejae (Yunan Dali), flos Pambariae Serratae (Yunnan Fengqing), and rhizoma Polygoni Cuspidati.

Caulis Entadae, namely calamus and rhizome, centipede (Yunnan herbal medicine), floor brush (Chinese middle plant), lycopodium clavatum, physalis pubescens (Guizhou folk prescription medicine collection), lycopodium parviflorum, climbing fern herb, Gomphrena hybrida, aeoliang tail herb, Pinus massoniana (Hunan medicine record), monkeyn herb, monkeyn tail, beefwood-like clubmoss herb, oolong but not river-crossing, Chinese yam, swertia fine-leaved clubmoss herb and Pinus massoniana (Yunnan Chinese herbal medicine). The source is whole plant of Lycopodium clavatum. The functions are mainly used for dispelling wind and eliminating dampness, relaxing tendons and activating collaterals, promoting urination and dissipating blood stasis. It is indicated for arthralgia due to dampness, numbness, arthralgia and myalgia, gonorrhea, and traumatic injury.

The extract of the leaves of pseudo-ginseng (Chinese herbal medicine roll P40) comes from: is root or whole plant of Notoginseng radix of Compositae. Medicine property: pungent flavor and warm nature. It enters liver and stomach meridians. The functions and indications are as follows: it has effects in dispelling blood stasis, stopping bleeding, relieving swelling, and relieving pain, and can be used for treating hematemesis, epistaxis, hematochezia, traumatic hemorrhage, traumatic swelling and pain, carbuncle, swelling, and sore. Pharmacology: 1, anti-inflammatory action; 2. local anesthesia action; 3. antimalarial effect.

Parasitic grass, also called parasitic vine, is a whole plant of the parasitic vine Henslouia frutescens Champ of Santalaceae, and has the effects of dissipating blood, reducing swelling and relieving pain.

In the raw material medicines of the dredging and bone nourishing fumigation application formula, other medicines are all traditional Chinese medicines recorded in the first part of the 2010 edition of Chinese pharmacopoeia or the first part of the 2005 edition of Chinese pharmacopoeia.

The Miao medicine formula mechanism of the arthralgia-relieving and bone-nourishing fumigation application formula is as follows:

1. main drugs: caulis Entadae (Miao medicine), Chinese alangium (Miao medicine), folium Artemisiae Argyi, herba Lycopodii, caulis et folium Gaultheriae Yunnanensis, Eucommiae cortex, folium Notoginseng, and caulis Spatholobi. The functions are as follows: expelling wind, removing dampness, dispelling cold, promoting blood circulation, removing obstruction in the channels and strengthening bones, wherein the local Miao medicine plays a major role in treating Jiangnang and Alangium chinense.

2. Adjuvant drugs: tripterygium wilfordii, radix seu caulis Opuntiae Dillenii, radix Alangii, caulis Sargentodoxae, caulis Akebiae, and lignum Pini nodi. The functions are as follows: clearing away heat and toxic material, eliminating swelling, dispersing pathogen accumulation, promoting blood circulation, and relieving pain. Wherein the local generation seedling drugs of tripterygium wilfordii, double sulcus and torch flower have stronger efficacy.

3. Monitoring the medicine: pawpaw, long pepper, clove (Miao medicine) and parasitic grass (Miao medicine). The efficacy is as follows: warming stomach, dispelling cold, regulating stomach and invigorating stomach. Wherein the Miao medicine is clove flower and parasitic grass which are special effective medicines.

The main medicine, the adjuvant medicine and the guardian medicine are used together, and have the total efficacies of expelling wind and removing cold, removing dampness and clearing and activating the channels and collaterals, clearing away heat and toxic material, reducing swelling and resolving masses, warming stomach and regulating stomach. The main treatment is as follows: rheumatic bone diseases (rheumatic osteoarthritis, rheumatoid diseases, ankylosing spondylitis, femoral head necrosis, prolapse (swelling) of lumbar intervertebral disc, gout, psoriasis skin diseases), degenerative osteoarthropathy, etc.

The invention has the advantages that:

(1) the invention relates to a dredging, bone-nourishing and fumigating application formula, which is derived from a Miao medicine secret formula treatment method of Liu family from Baoshan Miao village in Yunnan, wherein the Miao medicine secret formula is applied to folk family individuals for nearly one hundred years, and the Miao medicine secret formula and Chinese herbal medicines are applied to the hospital (including an outpatient department) for more than 20 years, and the main characteristics are that Miao medicines and Chinese herbal medicines are selected, a basic formula and an addition and subtraction formula are formed by applying the principle of dialectical treatment of Miao medicine and Chinese medicine, fumigation of a fumigation bed is adopted as a main method, and the methods of smearing, support application, bath, massage and magnetic therapy are added as. Through research and research, 4 and 16 types of inpatients are treated, and the effective rate of 1428 cases reaches 93.4%.

(2) The invention provides a novel obstruction-freeing bone-nourishing fumigation application formula, which follows the fundamental principles of overall thoughts and treatment based on syndrome differentiation of traditional Chinese medical miao doctors, starts from the whole body, achieves obstruction-freeing bone-nourishing effects due to diseases and treatment by people, and is not 'headache pain treatment and foot pain treatment'.

(3) According to the theory of 'cold and heat in traditional Chinese medicine' and 'sweat soaking and relieving', the medicine is applied to the skin, absorbed through capillary vessels, and from the outside to the inside, goes from the skin to the channels and collaterals to the bones, so that the aims of relieving pain and nourishing bones, removing diseases and recovering health are achieved. The transdermal drug delivery has wide route of administration, is easy to absorb, directly acts on the affected part, and can systemically regulate qi, channels, collaterals, bones and functions.

(4) The Chinese herbal medicines are mainly natural Miao medicine in Yunnan, so that the quality is good, the efficacy of the medicine is strong, the prescription composition is strict, the medicine is mainly assisted and assisted by assistance, and the efficacy is strong and lasting. Generally, the composition is effective for 3 days, and some patients feel pain relief even after the 1 st fumigation. After 90% of patients are treated according to the treatment course, the curative effect is remarkable and the consolidation can be achieved.

(5) The cost is low, the medicine is particularly suitable for rural patients, and the charge of 14-day treatment course is within 3600 yuan, which is far lower than the charge of medium and large hospitals.

(6) The fumigation application formula for dredging the arthralgia and nourishing the bone has no toxic or side effect, relieves or cures main diseases and restores the labor capacity after treatment according to the treatment course, and simultaneously can treat other diseases and enhance the resistance of a human body.

(7) The traditional Chinese medicine Miao medicine (secret recipe) fumigation and support application external treatment method (namely skin administration) is adopted for inheritance and is used for nourishing bones by the pain arthralgia, so that the aims of obvious curative effect, small side effect and low cost are fulfilled. Thereby inheriting and innovating the traditional Chinese medicine technology and solving the intractable diseases which can not be solved by large hospitals.

Detailed Description

The present invention will be further described with reference to specific examples so that those skilled in the art may better understand the present invention, but the present invention is not limited thereto.

Example 1

A traditional Chinese medicine fumigation formula for dredging arthralgia and nourishing bones comprises the following traditional Chinese medicine raw materials by weight:

200g of folium artemisiae argyi, 200g of eucommia ulmoides, 200g of ramulus uncariae cum uncis, 200g of lycopodium clavatum, 200g of tripterygium wilfordii, 200g of garden balsam stem, 200g of Chinese pine node, 200g of clove flower, 200g of acer truncatum, 200g of Chinese alangium, 200g of herba pyrrosiae, 150g of sargentgloryvine stem, 150g of akebia stem, 150g of pseudo-ginseng leaf, 150g of entada, 200g of caulis spatholobi, 200g of pawpaw, 150g of long pepper and 150g of parasitic grass.

Example 2

A Chinese medicinal composition, TONGBINYANGGUXU, is applied by fumigation. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight:

180g of folium artemisiae argyi, 220g of eucommia ulmoides, 180g of ramulus uncariae cum uncis, 220g of lycopodium clavatum, 180g of tripterygium wilfordii, 220g of garden balsam stem, 180g of Chinese pine node, 220g of clove flower, 180g of maple, 220g of Chinese alangium, 180g of herba pyrrosiae, 170g of sargentgloryvine stem, 130g of akebia stem, 170g of pseudo-ginseng leaf, 130g of entada, 220g of caulis spatholobi, 180g of pawpaw, 170g of long pepper and 130g of parasitic grass.

Example 3

A traditional Chinese medicine fumigation formula for dredging arthralgia and nourishing bones comprises the following traditional Chinese medicine raw materials by weight:

220g of folium artemisiae argyi, 180g of eucommia ulmoides, 220g of ramulus uncariae cum uncis, 180g of lycopodium clavatum, 220g of tripterygium wilfordii, 180g of speranskia tuberculata, 220g of Chinese pine node, 180g of clove flower, 220g of maple, 180g of Chinese alangium, 220g of herba pyrrosiae, 130g of sargentgloryvine stem, 170g of akebia stem, 130g of pseudo-ginseng leaf, 170g of climbing entada, 180g of caulis spatholobi, 220g of pawpaw, 130g of long pepper and 170.

Example 4

A traditional Chinese medicine fumigation formula for dredging arthralgia and nourishing bones comprises the following traditional Chinese medicine raw materials by weight:

150g of folium artemisiae argyi, 250g of eucommia ulmoides, 150g of ramulus uncariae cum uncis, 250g of lycopodium clavatum, 150g of tripterygium wilfordii, 250g of garden balsam stem, 150g of Chinese pine node, 250g of clove flower, 150g of maple, 250g of Chinese alangium, 15g of herba pyrrosiae, 200g of sargentgloryvine stem, 100g of akebia stem, 200g of pseudo-ginseng leaf, 100g of entada, 250g of caulis spatholobi, 150g of pawpaw, 200g of long pepper and 100g of parasitic grass.

Example 5

A traditional Chinese medicine fumigation formula for dredging arthralgia and nourishing bones comprises the following traditional Chinese medicine raw materials by weight:

250g of folium artemisiae argyi, 150g of eucommia ulmoides, 250g of ramulus uncariae cum uncis, 150g of lycopodium clavatum, 250g of tripterygium wilfordii, 150g of garden balsam stem, 250g of Chinese pine node, 150g of clove flower, 250g of maple, 150g of Chinese alangium, 250g of herba pyrrosiae, 100g of sargentgloryvine stem, 200g of akebia stem, 100g of pseudo-ginseng leaf, 200g of entada, 150g of caulis spatholobi, 250g of pawpaw, 100g of long pepper and 200g of parasitic grass.

Clinical trials were conducted on the Chinese medicine prepared in example 1, and the details are as follows

1. General data

1428 inpatients in the Qingyang Hongqi Chinese medicine hospital (the Yuan Qingyang ancient prescription medical hospital for rheumatism department) from 2016 to 2018 were selected and classified into 4 types and 16 diseases.

1.1 rheumatic diseases: 954 cases, 5 kinds. Wherein: rheumatoid arthritis (facet joint pathology) 671 cases; 128 cases of rheumatism (large joint lesion with general symptoms); 148 cases of connective tissue diseases, 2 cases of rheumatic fever and 2 cases of scleroderma.

1.2 osteoarthropathy: 411 cases, 5 kinds. Wherein: 68 cases of ankylosing spondylitis, 32 cases of femoral head necrosis, 218 cases of osteoarthritis, 28 cases of cervical spondylosis and 65 cases of lumbar spondylosis.

1.3 skin diseases: 45 cases and 3 cases. Wherein, the psoriasis is 39 cases, the eczema is 4 cases, and the acne is 2 cases.

1.4 immune, neurological, muscular diseases: 19 cases and 3 types. Wherein: raynaud's syndrome 7 cases, radiculitis 4 cases, myasthenia 8 cases.

2. Diagnostic criteria

2.1 Western diagnosis: diagnosis of rheumatic diseases according to the standard of diagnosis of rheumatic diseases, in the 12 th edition of "practical internal medicine"; immune, nerve and muscle diseases are diagnosed according to the book; the osteoarticular joint disease is diagnosed according to the Chinese bone injury science (teaching materials in higher colleges and universities); skin diseases are diagnosed according to "dermatology".

2.2 Chinese medicine diagnosis: rheumatic diseases, osteoarthropathy, and immune, nervous and muscle diseases refer to the clinical research guiding principle of arthralgia syndrome treatment in the Chinese medicine clinical disease diagnosis and treatment standards; meanwhile, refer to the diagnosis of neck, shoulder, waist and leg pain in the Chinese traditional bone injury science. The skin diseases are determined according to the nine edition of teaching materials of traditional Chinese medicine science by dialectical typing.

3. Medicine and prescription

The prescription of the obstruction-freeing bone-nourishing fumigation application provided by the invention is as follows: :

200g of folium artemisiae argyi, 200g of eucommia ulmoides, 200g of ramulus uncariae cum uncis, 200g of lycopodium clavatum, 200g of tripterygium wilfordii, 200g of garden balsam stem, 200g of Chinese pine node, 200g of clove flower, 200g of acer truncatum, 200g of Chinese alangium, 200g of herba pyrrosiae, 150g of sargentgloryvine stem, 150g of akebia stem, 150g of pseudo-ginseng leaf, 150g of entada, 200g of caulis spatholobi, 200g of pawpaw, 150g of long pepper and 150g of parasitic grass.

4. Method of treatment

For 1428 patients, external fumigation therapy, massage and physical therapy were performed, and some patients were administered with oral and topical Chinese medicinal liquids. The fumigation method comprises 4 steps, and is combined with 6 therapies of massage and physical therapy. Forming the treatment characteristic of 'six-in-one'.

4.1 Fumigation

Soaking the mixed raw materials for 3 hr, pouring into a big pot under a fumigation bed, adding water, boiling with open fire, and fumigating with hot gas on a bamboo fumigation bed. The patient feels comfortable hot, pores are opened, sweat is smooth, and the medicinal efficacy gradually enters the body.

4.2 applying

After fumigation, a fumigator applies a method to the whole body of a patient to promote the pores of the skin to be completely opened, so that the effective components of the traditional Chinese medicine can further permeate, and the effect of the medicine can be promoted to be exerted.

4.3 Hold in the palm and apply

According to the key local pathological changes of patients, after the patients are fumigated and smeared all over the body, the traditional Chinese medicine residue bag is put on the joints, the spinal column and other parts for hot compress, and the absorption of the medicine at the key parts is promoted.

4.4 soaking

The appliance is used after the support is applied, so that the patient can soak and bath the feet and hands, and the qi and blood channels and collaterals of the hands and feet can promote the further circulation and enhancement of the drug effect to the whole body.

4.5 massage

After the first 4 kinds of fumigation treatment are completed, the masseur performs four kinds of massage manipulations on the patient, so as to harmonize the emotion and the discomfort of the whole body of the patient and play a role in auxiliary treatment.

4.6 for some osteoarthropathy patients, the electrothermal physiotherapy is carried out simultaneously to enhance the medicine penetration and improve the curative effect.

The above 6 steps of treatment were completed, and the time required for each patient was within 2 hours. In the absence of any particular disease or other complications, the above-mentioned treatment is generally performed 2 times a day. The treatment time can be adjusted or a certain method can be suspended when a special disease condition exists.

5. Principle of treatment based on syndrome differentiation

The hospital uses two sets of medical theories of traditional Chinese medicine and Miao medicine as guidance, and concretely adheres to the following characteristic principle of dialectical treatment:

5.1 following the basic rules of traditional Chinese medicine and pharmacy

5.1.1 uses the Bi syndrome theory in Nei Jing as guidance. Su Wen Bi Lun (plain questions and Bi Lun) cloud: for arthralgia syndrome, it is also the case that the qi is strongly affected by wind, cold and dampness. It indicates that wind-cold-dampness is the cause of the disease, and the arthralgia syndrome is divided into five types of arthralgia syndrome, namely bone arthralgia syndrome, muscle arthralgia syndrome, vessel arthralgia syndrome and skin arthralgia syndrome according to the different time and parts of the disease. Based on the preponderance of wind-cold-dampness, it is classified into pain arthralgia, migratory arthralgia and migratory arthralgia. It is also indicated that arthralgia syndrome will not be cured for a long time and invade five zang organs, which is called "arthralgia syndrome of five zang organs". On the one hand, the pathogenesis of arthralgia is that after the meridians and collaterals of the body are attacked by wind, cold and dampness, the circulation of qi and blood is not smooth, so that pain, soreness, heaviness, numbness, swelling and difficulty in flexion and extension of the skin, meridians and collaterals, muscles, bones and muscles, joints and the like are caused. On the other hand, the deficiency of five zang organs, especially the deficiency of liver and kidney, tends to invade exogenous pathogens, and the above symptoms appear. If the arthralgia syndrome further develops, the pathogenic factors from shallow to deep and from the meridians to the zang-fu organs will cause the pathological changes of the zang-fu organs, such as muscular atrophy, joint deformity or stiffness, or heart, lung, liver and kidney affected by phlegm-fluid retention, water-vapor and cough.

According to a prescription prepared by secret of Miao medicine, a plurality of Miao medicines and Chinese herbal medicines are selected for compatibility, and the principle is that wind-cold, dampness and heat evil qi are distinguished according to invasion levels of disease pathogens, and the medicines are reasonably dispatched according to two types of wind-cold-dampness arthralgia (migratory arthralgia, painful arthralgia and migratory arthralgia) and heat arthralgia in combination with visceral lesion dialectical.

5.1.2 external treatment is applied with the core concept of holism. The method firstly applies the prescription mainly for relieving exterior and sweating, expelling wind and cold to fumigate the whole body, opens pores of the skin and leads a patient to sweat, and pathogenic factors are firstly eliminated from the surface, and the method is the same as the 'sweating method' which is one of the 'eight methods'. Also from the holistic concept, continuous fumigation of the whole body is intended to discharge deep-level cold-damp toxin from the surface again, and is supplemented with the addition and subtraction of drugs for strengthening tendons and bones, dredging collaterals and promoting blood circulation. The last prescription also adopts a whole body fumigation method, and the medicine focuses on strengthening the exterior and arresting sweating, tonifying qi and nourishing blood, and strengthening the muscles and bones, thereby achieving the purposes of strengthening the whole body yang and regulating the balance of yin and yang.

5.1.3 the curative effect is strengthened by the therapeutic principle of treating both principal and secondary aspect of disease. Su Wen heritage acanthosis treatise says: the healthy qi exists in the interior and the pathogenic factors cannot be dried. The Wenshao appraised the Hui Bing: when the pathogenic factors attack, the qi must be deficient. The arthralgia syndrome is caused by the deficiency of vital qi, the deficiency of liver and kidney, and the invasion of pathogenic wind, cold and dampness. The hospital insists on treating the symptoms first and then treating both the principal and secondary aspects simultaneously, and then consolidating the constitution and strengthening the body.

5.2 inherits the theory and practical experience of Miao medicine

The treatment and medication of the hospital come from the secret recipes handed down by several generations of Miao medicine in Yunnan, and the following experience is particularly adhered to in clinical practice.

5.2.1 the source of the herb is genuine. Dozens of common seedling drugs are all from original ecological plants naturally grown in original forests of Baoshan in Yunnan, are collected and screened by experienced relatives, and have short storage time, original taste and flavor and strong efficacy.

5.2.2 prescription administration is legal. Although fumigation belongs to external treatment, the prescription of fumigation in the hospital is flexible in compatibility according to the clinical conditions, not only basic medicines but also added or subtracted medicines, the principles of Miao medicine' cold disease heat treatment, heat disease cold treatment and odd prescription are inherited, and the prescription medicines are divided into three types of prescriptions of leading medicines, ground medicines and monitoring medicines. According to the theory that Miao doctors attribute the cause of diseases as "virulence", the prescription is focused on counteracting toxic pathogen and expelling toxin.

5.2.3 the fumigating method is unique. The fumigation bed is simply and conveniently applied after being improved for a plurality of times, four stages in one treatment are continuously applied in turn, the efficacy of the medicine gradually enters, the effects of sweating and toxin expelling are obvious, and the curative effect is further consolidated by adding massage and physical therapy. Moreover, according to the summary of the family-handed and clinical experience, the fumigation is carried out twice a day, the medicine effect can be continuously exerted, wind, cold and damp evil are gradually eliminated, and the healthy qi is gradually strengthened, so that the treatment effect is achieved and consolidated.

5.2.4 pay attention to diet daily life. The patient diet daily life notice is formulated, and the requirements are provided in the aspects of strengthening nutrition, paying attention to diet contraindication, properly exercising, avoiding heavy burden labor, avoiding wind and cold, preventing severe cold recurrence, calming the heart and resting, matching various treatments and the like, so that the treatment progress and the curative effect are ensured to be improved.

6. Analysis and determination of therapeutic effect

6.1 therapeutic Standard

The therapeutic effect judgment standards of hospitalization for 7 diseases are formulated according to the 'standard of therapeutic effect for diagnosis of clinical disease symptoms of traditional Chinese medicine':

third, research results and discussion

6.2 assay of efficacy results

The medical record data of 1428 cases shows that 988 cases are effective, which accounts for 69.19%, 308 cases are effective, which accounts for 21.57%, and 34 cases are healed, which accounts for 2.38%, 98 cases are ineffective, which accounts for 6.86%, and the total effective rate is 93.14%. The curative effect is determined according to the related items in the book of the standard of curative effect for diagnosing the clinical symptoms of the traditional Chinese medicine [4 ]. The classification and statistics of the treatment effects of the disease species are shown in the following table:

typical cases

Ankylosing spondylitis

The traditional Chinese medicine composition is used for treating a male in a hospital 15 years old, 8-day initial diagnosis in 2016, 5109-hospital admission, traditional Chinese medicine decoction treatment, unsmooth general multi-joint pain and double ankle joint swelling pain caused by no obvious inducement before 5 years old, poor effect, even four-year early pain aggravation, lumbar vertebra joint and double hip joint pain, slight limitation of flexion and extension activities, diagnosis in a Beijing hospital, examination of H L A-B27 positivity, diagnosis of 'ankylosing spondylitis', treatment with medicines such as Ying-Taiqing, even effect, even pain after drug withdrawal, mild winter and summer disease, even pain after cold, walking failure in pain, recently, even symptoms aggravation, pain in the waist and back, unfavorable turning of head, clear consciousness, mental pain, no fever, aversion to cold, no chest distress, no short breath, no sleep diet, normal stool, diagnosis in a hospital, diagnosis of traditional Chinese medicine wet-holding type (retention of phlegm) and slight pain, moderate pain after 8-day initial diagnosis, hospitalization number of a hospital admission, no clinical trial with a hospital admission, no obvious walking by a traditional Chinese medicine composition of a traditional Chinese medicine bag, no obvious walking, no heat, no clinical trial of a left side wall, no clinical trial of a knee pain, no clinical trial of a moderate walking, no clinical trial of a left side, no clinical trial of a moderate walking, no clinical trial, no obvious walking, no clinical trial of a moderate walking, no warm leg, no clinical trial of a moderate walking, no warm leg, no clinical trial of a moderate walking, no warm leg, no clinical trial of a moderate walking, no clinical trial of a moderate leg, no clinical trial of a moderate walking, no clinical trial of a moderate leg, no clinical.

Bilateral femoral head necrosis

A Yuan male is 27 years old and initially diagnosed in 2017, 12 months and 13 days. Medical record number: 6060, 1 patient complains of no obvious inducement before 1 year and has pain in left knee joint, especially when walking, the pain is gradually aggravated, and the patient has mild pain in both hips, limited movement of bending down, squatting and difficulty in walking. The diagnosis of the Hospital of Homoku in Neihan Lianhu is the bilateral femoral head necrosis, and the oral traditional Chinese medicine (with specific medicine and dosage being unknown) is given for treatment, so the effect is poor. The onset of this disease is marked by mental clarity and spiritual function. Has no chest distress, short breath, no nausea, no vomiting, no blurred vision, no abdominal distention and pain, no appetite and sleep, and normal stool and urine. Admission diagnosis: traditional Chinese medicine diagnosis: western diagnosis for bone disease typing (qi stagnation and blood stasis type): bilateral femoral head necrosis. Auxiliary inspection: hospital MRI cues: 1. the left femur lower segment is subjected to multiple spot sheet abnormal signals, bone infarction is considered, and a review is recommended: the signal of the anterior cruciate ligament of the left knee joint is increased, and the injury is not excluded; a small amount of fluid accumulated in the left knee joint. 2. Lumbar 5 sacral 1 disc herniation (central left type); lumbar 4/5 herniation of intervertebral disc; the curvature of the lumbar vertebrae becomes slightly straight. And (3) prompting by using an X-ray of an outside hospital: 1. bilateral avascular necrosis of the femoral head. 2. The left knee has no pathological changes of bones and joints. External hospital magnetic resonance prompt: bilateral avascular necrosis of the femoral head (stages III-IV). Admission to the examinee: the double hip is obvious in tenderness; positive in bilateral pelvic compression test. The right flank transverse line is 1cm higher than the left. The test of the double lower limbs is positive in a 4-shaped test, the right knee is dull in reflection, the squat and squat movements are not limited, and the right lower limb is 1cm shorter than the left lower limb in the horizontal position. The right hallux toenail is dark black, and the nail plate is thickened. The rest parts have no positive sign. After treatment of traditional Chinese medicine external treatment fumigation therapy, traditional Chinese medicine inunction therapy, traditional Chinese medicine package therapy, traditional Chinese medicine heat package therapy, massage and the like for 4 courses of treatment, physical examination is carried out: no pressure pain on the double hips; the bilateral pelvic crush test was weakly positive. The right flank transverse line is 1cm higher than the left. The double-lower-limb '4' -shaped test is weak positive, the right knee is slow in reflection, the squat and squat movements are not limited, and the right lower limb is 0.5cm shorter than the left lower limb in the horizontal position. The patient is discharged after the disease condition is obviously improved.

Prolapse of lumbar intervertebral disc

A woman in 24 years old can be treated in 2016, 7 and 24 days for initial diagnosis in our hospital. Hospitalization number: 5086 the patient feels sudden pain in waist three years before complaint and radiates to right lower limb, and has difficulty in sleeping and turning over, limited bending movement, aggravation of lumbago due to rain in the shade, pain of both lower limbs, pain of both hip joints, obvious pain during hip bending, and limited squat movement. The disease is diagnosed as lumbar disc herniation in the hospital of people in Qingyang city, oral medication (the specific name of the medicine is unknown) is given for treatment, pain is relieved after the medication, and symptoms are repeated after the medication is stopped. Patients were in my hospital for further treatment, physical examination: pale tongue with white and greasy coating, deep and tight pulse, obvious tenderness in the lumbar 4 and 5 intervertebral spaces, slightly limited left and right lateral bending, obviously limited forward bending and backward bending activities, difficult turning over and getting up, positive bilateral sciatic nerve body surface projection tenderness, positive straight leg elevation test, positive reinforcement test, positive pelvis extrusion test and positive bilateral '4' test. 2016-07-24 lumbar X-ray film prompt: the lumbar 4-5 intervertebral space is widened. Traditional Chinese medicine diagnosis: cold-dampness syndrome, western medicine diagnosis: prolapse of lumbar intervertebral disc. After 4 courses of external treatment fumigation treatment with traditional Chinese medicines, physical examination is performed: the tongue is red, the coating is thin and white, and the pulse is deep and thready. The joints of the two fingers and the joints of the two wrists have no swelling, no tenderness and no limitation on flexion and extension activities. The double elbow joints have no pressure pain, the flexion and extension activities are not limited, and the internal rotation and external expansion activities are not limited. The joints of the shoulders have no pressure pain, and the lifting and extending movement is not limited. The spinous process of the cervical vertebra has no pressure pain, no pressure pain beside the spinous process and no limitation of head rotation movement. The spine has no lateral bending and no deformity, the physiological curvature of the lumbar exists, the spinous processes of the waist 4 and 5 have no pressure pain, the side of the spinous processes has no pressure pain, the left and right lateral bending and the bending movement are not limited, and the patient can turn over and get up freely. The bilateral sciatic nerve body surface projection is not painful to press, the straight leg raising test is negative, the strengthening test is negative, the pelvic squeezing test is negative, the bilateral '4' test is negative, and the hip bending and knee bending test is negative. The patient is discharged after the disease condition is improved.

Psoriasis disease

A certain grandchild is 25 years old, and the woman is initially diagnosed in our hospital on the 25 th month of 2018. Hospitalization number: 6302 patients complain about 6 years ago that many red spots of skin lesions appear on the whole body, the edges are clear, the itching is obvious, even at night, no dandruff falls off, and the skin lesions on the whole body gradually disappear after the treatment of oral administration (detailed medicine name and dosage) and external application of cream, etc. when the patients visit local clinics. Before 1 week, after eating seafood, the skin lesions of the whole body are reoccurred and gradually worsened, particularly, a large amount of silvery white scurf is separated from the chest, abdomen, waist, back and lower limbs, the scurf is distributed in a map shape, the pruritus is obvious, and the symptoms are not obviously improved after the local clinic purchases oral medicine for treatment. Physical examination: the tongue is pale red, the tongue coating is thin and white, and the pulse is thready and deep. A large number of spots and red flaky lesions are visible on the skin of the whole body, especially on the chest, abdomen, waist, back and lower limbs. The skin damage can have a small amount of silvery white desquamation, the edge is clear, and the color can not be faded after pressing. The skins of the chest, the back and the waist are distributed in a spot-sheet shape, the epidermis is red, the edge is clear, the color cannot be changed when the skin is pressed, the skin damage of the double lower limbs is distributed in a spot-sheet shape and a map shape, the epidermis is light red, a small amount of silvery white dry scraps can be seen at the far ends of the double lower limbs, the edge is clear, and the color cannot be changed when the skin is pressed. Traditional Chinese medicine diagnosis: and (3) porrigo: typing: blood heat and toxic excess type, western medicine diagnosis: after 24 days of external treatment fumigation treatment of the traditional Chinese medicine, patients have self complaints, the whole body itch disappears, and the physical examination is as follows: the tongue is pale red, the tongue coating is thin and white, and the pulse is thready and deep. A few spots and flaky reddish skin lesions can be seen on the skin of many parts of the whole body. The skin damage has no silver white desquamation, clear edge and no fading after pressing. The skin of the chest, the back and the waist is distributed in a spot-sheet shape, the skin is light red, the edge is clear, and the color is not faded when pressed; the skin damage of the two lower limbs is distributed in a spot-sheet shape and a map shape, the skin color is normal, the far ends of the two lower limbs have no silver white dry scraps, the edges are clear, and the color can not be faded when pressed. So far, the disease condition of the patient is not repeated.

Cervical spondylosis of cervical vertebra

Some certain Yang, female, age 35, first diagnosis in 04/2018 and day 06. Hospitalization number: 6231, patients do not have obvious reasons before complaint for 5 years and have obvious feeling of soreness of neck and waist, and the pain of soreness and sleepiness of neck and waist is obvious when sitting for a long time or tired, and the feeling of soreness and sleepiness is obviously relieved after massage and massage. No drug was taken. The lumbar pain appears after sitting for a long time before 5 days, the pain cannot be relieved after massage, the patients visit the local hospital to diagnose the lumbar disc herniation, and the treatment effects are poor by giving acupuncture and moxibustion massage, oral medicines and the like. The patients need further treatment, and then see the doctor in the hospital, wherein the body is examined to be pale red, white fur, thin and deep pulse, tenderness in the neck 5, 6 and 7 centrum, tenderness beside the spinous process, low head and limited activity of turning the head. Tenderness of the lumbar 4 and 5 vertebral bodies and mild tenderness beside the spinous processes. Positive results of hip and knee bending tests. And (3) diagnosis: traditional Chinese medicine diagnosis: bone disease, typing: 1. wind-cold-dampness type 2 and cold-dampness syndrome type western medicine diagnosis: 1. cervical spondylosis 2, lumbar disc bulging and contracting, after 15 days of external treatment by traditional Chinese medicine fumigation, the tongue is reddish, the coating is white, the pulse is fine and deep, the neck 5, 6 and 7 centrums are painless, the side of the spinous process is painless, the head is lowered, and the head turning movement is not affected. No pain is caused to the lumbar 4 and 5 centrum and the side of the spinous process. The hip and knee bending test is negative. The patient is discharged after the disease condition is obviously improved.

Rheumatoid arthritis

The traditional Chinese medicine for treating knee joint pain is characterized by firstly diagnosing a woman 33 years old, 2017 years old, 11 months 03 days, hospitalization number: 5978, patient self-complaint before 17 years old, double elbow joint pain caused by humid living environment, diagnosed as rheumatoid arthritis by affiliated hospitals of local medical universities, orally administered tripterygium wilfordii (specific medicine and unspecified dose) and other medicine treatment, poor effect, scald of right knee joint in 2004, slight limitation of activity, diagnosis after passing to Song river rheumatism hospitals, orally administered traditional Chinese medicine capsules (specific medicine and unspecified dose), obvious effect, early symptoms aggravation in 2009 year, double elbow joint pain, gradual right elbow joint deformation, no stretching, dressing, limited combing head, double knee joint swelling, obvious pain, pain after walking fine movement, remitting symptoms after rest, diagnosis to Sihe hospital belonging to Xinhe department of Star river, diagnosis of rheumatoid arthritis, diagnosis of oral medicine (specific medicine and unspecified dose) and other medicine treatment, poor effect, weak tongue pain, moderate tongue pain of double elbow joints, gentle tongue movement of tongue, gentle tongue, moderate tongue.

Radiculitis of right lower limb

The traditional Chinese medicine bag is used for treating a certain female 30 years old, early diagnosis is carried out at 8 and 6 days in 2016, hospitalization is 5105, the patient self-complains that the waist and hip part is in acid state and is sleepy in the early pregnancy period of one year and a half, the dorsal side of the right lower limb is intermittent and has the feeling of electric shock, the patient self-conscious right lower limb is not in the feeling of power when walking, the patient is normal when standing or resting, the symptoms are not obviously relieved after delivery, the right lower limb is in the unstressed state, the patient is not limited when standing or squatting and has no obvious pain, the patient is not limited when walking, the patient is in the early pregnancy period of 2016, the patient is diagnosed as ' lumbar disc herniation and compact iliotitis ' in hospitalization by traditional Chinese medicine in Gansu province, the patient is subjected to physical therapy such as massage, cupping, small needle knife therapy and treatment, the curative effect is poor, then the patient is diagnosed in the hospital affiliated medical hospital in the general hospital in 2016 and the former 3 months, the prior to the libido-defecating state, the diagnosis is given to the diagnosis of ' peripheral neuropathy, the patient ' peripheral neuropathy, tuberculous meningitis sequelae, anxiety and depression state ', the patient is free from the patient ' peripheral neuropathy, the patient's pain, the patient is diagnosed as the patient's of blood stasis, the patient's physiological pain, the patient's pain in the patient's of the patient's disease, the patient's of the patient's disease, the patient's disease.

Claims (10)

1. The obstruction-freeing, bone-nourishing and fumigating application formula is characterized by comprising the following traditional Chinese medicine raw materials in parts by weight:

150 portions of artemisia leaf, 150 portions of eucommia bark, 150 portions of ramulus Uncariae cum uncis, 150 portions of lycopodium clavatum, 150 portions of tripterygium wilfordii, 150 portions of speranskia tuberculata, 150 portions of Chinese pine knot, 150 portions of clove, 150 portions of Acer buergerianum, 150 portions of Alangium platanifolium, 150 portions of pyrum glauca, 100 portions of Sargentodoxa cuneata, 100 portions of akebia stem, 200 portions of Panax notoginseng leaf, 100 portions of Alangium platyphylla, 150 portions of suberect spatholobus stem, 250 portions of pawpaw, 100 portions of piper perny, and 200 portions of parasitic grass.

2. The obstruction-freeing, bone-nourishing and fumigating application formula according to claim 1 is characterized by comprising the following traditional Chinese medicine raw materials in parts by weight: 180 portions of artemisia leaf, 180 portions of eucommia bark, 180 portions of ramulus Uncariae cum uncis, 220 portions of lycopodium clavatum, 180 portions of tripterygium wilfordii, 180 portions of speranskia tuberculata, 180 portions of Chinese pine knot, 180 portions of clove, 180 portions of Acer buergerianum, 180 portions of Alangium platanifolium, 180 portions of pyrum glauca, 130 portions of Sargentodoxa cuneata, 130 portions of akebia stem, 130 portions of notoginseng leaf, 130 portions of Alangium platyphylla, 170 portions of spatholobus stem, 180 portions of pawpaw, 220 portions of piper longum, 130 portions of piper longum and 130 portions of parasitic grass.

3. The obstruction-freeing, bone-nourishing and fumigating application formula according to claim 2 is characterized by comprising the following traditional Chinese medicine raw materials in parts by weight: 200 parts of folium artemisiae argyi, 200 parts of eucommia ulmoides, 200 parts of double-hook, 200 parts of lycopodium clavatum, 200 parts of tripterygium wilfordii, 200 parts of garden balsam stem, 200 parts of Chinese pine node, 200 parts of clove flower, 200 parts of maple, 200 parts of Chinese alangium, 200 parts of pitaya flower, 150 parts of sargentgloryvine stem, 150 parts of akebia stem, 150 parts of pseudo-ginseng leaf, 150 parts of climbing entada, 200 parts of caulis spatholobi, 200 parts of pawpaw, 150 parts of long pepper and 150 parts of parasitic grass.

4. The use of the dredging and bone-nourishing fumigation formula of claim 1, 2 or 3 in the preparation of a medicament for treating rheumatoid bone diseases.

5. Use of the arthromyodynia-promoting bone-nourishing fumigation formula of claim 1, 2 or 3 in the preparation of a medicament for treating rheumatoid osteoarthritis.

6. Use of the arthromyodynia-curing bone-fumigating application formula of claim 1, 2 or 3 in the preparation of a medicament for treating rheumatoid arthritis.

7. The use of the Tongbi Gugu fumigation formula of claim 1, 2 or 3 in the preparation of a medicament for treating ankylosing spondylitis.

8. The use of the dredging and nourishing bone fumigation formula of claim 1, 2 or 3 in the preparation of a medicament for treating femoral head necrosis.

9. Use of the obstruction-freeing bone-nourishing fumigation formula of claim 1, 2 or 3 in the preparation of a medicament for treating gout.

10. Use of the obstruction-freeing bone-nourishing fumigating preparation of claim 1, 2 or 3 in the preparation of a medicament for treating psoriatic skin diseases.