CN104306851A - Method for preparing medicinal liquor for treating protrusion of lumbar intervertebral disc - Google Patents

Method for preparing medicinal liquor for treating protrusion of lumbar intervertebral disc Download PDF

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Publication number
CN104306851A
CN104306851A CN201410549663.9A CN201410549663A CN104306851A CN 104306851 A CN104306851 A CN 104306851A CN 201410549663 A CN201410549663 A CN 201410549663A CN 104306851 A CN104306851 A CN 104306851A
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parts
rhizoma
intervertebral disc
lumbar intervertebral
radix
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CN104306851B (en
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周遂记
温自力
周亚光
李中亚
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HENAN SIZHITANG PHARMACEUTICAL Co Ltd
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HENAN SIZHITANG PHARMACEUTICAL Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486Millettia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/89Cyperaceae (Sedge family)
    • A61K36/8905Cyperus (flatsedge)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964Anemarrhena
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9062Alpinia, e.g. red ginger or galangal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

Abstract

The invention provides a method for preparing medicinal liquor for treating protrusion of lumbar intervertebral disc. The method comprises the following steps: grinding prepared kusnezoff monkshood root, galangal, clove and kudzu vine root, steaming, cooling, uniformly mixing with soaked millet, adding mixture of distiller yeast and water, and fermenting in a ceramic container; adding water into the fermented material, carrying out ultrasonic treatment, and filtering to obtain decoction A; grinding spatholobus suberctu, angelica sinensis, polygonatum kingianum, rhizoma cyperi and rhizoma anemarrhenae, adding bacillus natto and sterile water, uniformly mixing, and fermenting in a ceramic container; adding distilled liquor into the fermented product, adding distilled liquor, soaking, heating to 50-60 DEG C, insulating, cooling, and filtering to obtain filtrate to obtain decoction B; mixing the decoction A and the decoction B to obtain decoction C; adding brown granulated sugar, which is fried to coked yellow in an iron pan, into the decoction C, stirring until the brown granulated sugar is completely dissolved, and filtering to obtain the decoction which is the medicinal liquor for treating protrusion of lumbar intervertebral disc. According to the medicinal liquor, drugs play effects by assistance of liquor, monarch, minister, assistant and guide drugs are matched and synergized to play effects of diminishing inflammation, dispelling wind, relieving arthralgia, dredging collaterals to relieve pain, and activating blood circulation to remove stasis.

Description

A kind of preparation method for the treatment of the medicated wine of prolapse of lumbar intervertebral disc
Technical field
The present invention relates to a kind of medicated wine, specifically a kind of preparation method for the treatment of the medicated wine of prolapse of lumbar intervertebral disc.
Background technology
Intervertebral disk hernia is because bad living habit and work habit cause, bad sitting posture, stance and to bend over for a long time or heavy physical labour is all pathogenic factor.Outstanding intervertebral disc is urged to nerve, just have numb, swell, myasthenia of limbs, the symptom of pain.
Clinical statistics shows, it is one of the most common illness of Orthopaedics Clinic that lumbar intervertebral disc prominent (taking off) goes out disease, is also the most common reason of lumbago and skelalgia.Review history, just describe the outward appearance of intervertebral disc as far back as Vesalius in 1543.The twenties in 20th century, the Shmorl of Germany has successively delivered the article of 11 sections of relevant intervertebral disc dissections and pathology, has done study more widely intervertebral disc.1932, first Barr proposes prolapse of lumbar intervertebral disc was the possible reason of lumbago and skelalgia.Thereafter, Barr and Mixter proposes concept and the Therapeutic Method of Concerning Protrusion of Lumbar Intervertebral Disc first.Hereafter, the basic research of disease is gone out also progressively deeply to lumbar intervertebral disc prominent (taking off), thus more improves the clinical diagnosis of primary disease and the effect for the treatment of.
Summary of the invention
The present invention seeks to the deficiency for solving the problems of the technologies described above, providing a kind of preparation method for the treatment of the medicated wine of prolapse of lumbar intervertebral disc, prepared medicated wine, can dispel the wind, dehumidify, dispersing cold for relieving pain, for the treatment of prolapse of lumbar intervertebral disc.
Treat a medicated wine for prolapse of lumbar intervertebral disc, the parts by weight of each crude drug of described medicated wine are: Radix Aconiti Kusnezoffii Preparata 20-25 part, Radix Angelicae Sinensis 8-10 part, Flos Caryophylli 8-10 part, Rhizoma Alpiniae Officinarum 8-10 part, Rhizoma Cyperi 5-8 part, Caulis Spatholobi 5-8 part, Radix Puerariae 8-10 part, Rhizoma Polygonati 5-8 part, brown sugar (Saccharum Sinensis Roxb.) 30-33 part, yellow Semen setariae 50-100 part and Rhizoma Anemarrhenae 5-8 part.
The parts by weight of each crude drug of medicated wine of described treatment prolapse of lumbar intervertebral disc are preferably: the parts by weight of each crude drug of described medicated wine are: Radix Aconiti Kusnezoffii Preparata 25 parts, Radix Angelicae Sinensis 8.3 parts, Flos Caryophylli 8.3 parts, Rhizoma Alpiniae Officinarum 8.3 parts, Rhizoma Cyperi 6 parts, Caulis Spatholobi 6 parts, Radix Puerariae 8 parts, Rhizoma Polygonati 5 parts, brown sugar (Saccharum Sinensis Roxb.) 30 parts, yellow Semen setariae 80 parts and the Rhizoma Anemarrhenae 5 parts.
The preparation method of the medicated wine of described treatment prolapse of lumbar intervertebral disc, comprises the following steps:
Step one, get Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Flos Caryophylli, Rhizoma Alpiniae Officinarum, Rhizoma Cyperi, Caulis Spatholobi, Radix Puerariae, Rhizoma Polygonati, brown sugar (Saccharum Sinensis Roxb.), yellow Semen setariae and the Rhizoma Anemarrhenae respectively according to above-mentioned parts by weight, for subsequent use;
Step 2, got Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and powder of Radix Puerariae are broken into the Chinese medicinal granule that particle diameter is 2.5-5.0mm; Steam 50-70 minute at gained Chinese medicinal granule is placed in 95-100 DEG C, take out and be cooled to 40-45 DEG C, for subsequent use; In got yellow Semen setariae, add its quality 5-10 water doubly, soak 5-8 hour, pull out and drain, for subsequent use;
Step 3, will Radix Aconiti Kusnezoffii Preparata, the Rhizoma Alpiniae Officinarum of 40-45 DEG C be cooled to after steaming, obtain mixture after Flos Caryophylli and Radix Puerariae Chinese medicinal granule and the yellow Semen setariae mix homogeneously after soaking, add distillers yeast and the quality 15-20 water doubly of its quality 2-3% in the resulting mixture, mix homogeneously is placed in ceramic vessel and ferments 2-3 days again, takes out fermented product; In gained fermented product, add its quality 15-20 water doubly, ultrasonic Treatment 2-3 hour under 100-200 kHz power, filters to obtain medicinal liquid A, for subsequent use;
Step 4, got Caulis Spatholobi, Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Cyperi and Rhizoma Anemarrhenae powder are broken into the Chinese medicinal granule that diameter is 3.0-8.0mm; In gained Chinese medicinal granule, add the Bafillus natt of its quality 2-3% and the sterilized water mix homogeneously of quality 2-4%, be placed in ceramic vessel and ferment 2-3 days, take out tunning; In gained tunning, add tunning quality 3-6 Chinese liquor doubly, soak 3-4 hour post-heating to 50-60 DEG C of insulation 2-3 hour, be then cooled to room temperature, cross leaching filtrate, obtain medical liquid B, for subsequent use;
Step 5, by preparation medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C; Got brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan to be fried to coke yellow, joins in medicinal liquid C, is stirred to and dissolves completely, leaves standstill 24-26 hour, filters, and gained medicinal liquid is the medicated wine for the treatment of prolapse of lumbar intervertebral disc.
Beneficial effect is:
1, medicated wine of the present invention is formed by Chinese crude drug compatibilities such as Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Rhizoma Alpiniae Officinarum, Flos Caryophyllis; Wherein Radix Aconiti Kusnezoffii acrid in the mouth, hardship, hot in nature, very toxic, and GUIXIN liver spleen channel, has effect of antalgic, expelling wind and removing dampness, to anemofrigid-damp arthralgia, has good effect, is monarch drug; Radix Angelicae Sinensis sweet in the mouth is pungent, warm in nature, has the merit of soothing liver-QI of enriching blood, promoting blood circulation and stopping pain, is ministerial drug; Rhizoma Alpiniae Officinarum acrid in the mouth, hot in nature, return taste warp, can warming spleen and stomach for dispelling cold pain relieving, be adjuvant drug; Flos Caryophylli acrid in the mouth, warm in nature, return spleen lung meridian, have warming middle-JIAO to send down the adverse QI, effect of reinforcing the kidney and supporting YANG.Chinese liquor in addition, warming the meridian and activating blood circulation, dredging collateral cold expelling.Wine assisting drug, wine helps medicine gesture, four medicine compatibilities, and monarch, coordinates mutually, antiinflammatory, dispel the wind a surname numbness, removing obstruction in the collateral to relieve pain, Eradicates blood stasis and smoothing collaterals of invigorating blood circulation, especially to treatment prolapse of lumbar intervertebral disc there is good therapeutic effect; Use the medicated wine wine treatment for the treatment of prolapse of lumbar intervertebral disc can reach satisfied effect; The medicated wine treatment prolapse of lumbar intervertebral disc of simultaneously treating prolapse of lumbar intervertebral disc has convenience, safety, cheapness, eutherapeutic feature.
2, the present invention adopts distillers yeast fermentation Radix Aconiti Kusnezoffii, Rhizoma Alpiniae Officinarum, Flos Caryophylli and Radix Puerariae Chinese medicinal granule in ceramic vessel, the active ingredient being beneficial to treatment prolapse of lumbar intervertebral disc in Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and Radix Puerariae can be separated out, and the Caulis Spatholobi of follow-up bacillus natto to ferment, Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Cyperi and the Rhizoma Anemarrhenae medicinal liquid mixing after reach better therapeutic effect; Bafillus natt is in the middle of various beneficial bacterium, and preferably can go directly to environment resistance one of strain of small intestinal, can change human enteric bacteria and to grow thickly state, help digest function normalization after oral, to make defecation smooth and easy, maintains body physiological environmental protection.Can produce acid, regulating intestinal canal flora, enhancing animal cell immunity is put should; Adopt bacillus natto to ferment Caulis Spatholobi, Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Cyperi and the Rhizoma Anemarrhenae, except medicine being played to greatest extent except its effect, all right adjusting immunity of human body, improves the utilization rate of medicine.
Detailed description of the invention
Treat a medicated wine for prolapse of lumbar intervertebral disc, the parts by weight of each crude drug of described medicated wine are: Radix Aconiti Kusnezoffii Preparata 20-25 part, Radix Angelicae Sinensis 8-10 part, Flos Caryophylli 8-10 part, Rhizoma Alpiniae Officinarum 8-10 part, Rhizoma Cyperi 5-8 part, Caulis Spatholobi 5-8 part, Radix Puerariae 8-10 part, Rhizoma Polygonati 5-8 part, brown sugar (Saccharum Sinensis Roxb.) 30-33 part, yellow Semen setariae 50-100 part and Rhizoma Anemarrhenae 5-8 part.
The parts by weight of each crude drug of medicated wine of described treatment prolapse of lumbar intervertebral disc are preferably: the parts by weight of each crude drug of described medicated wine are: Radix Aconiti Kusnezoffii Preparata 25 parts, Radix Angelicae Sinensis 8.3 parts, Flos Caryophylli 8.3 parts, Rhizoma Alpiniae Officinarum 8.3 parts, Rhizoma Cyperi 6 parts, Caulis Spatholobi 6 parts, Radix Puerariae 8 parts, Rhizoma Polygonati 5 parts, brown sugar (Saccharum Sinensis Roxb.) 30 parts, yellow Semen setariae 80 parts and the Rhizoma Anemarrhenae 5 parts.
The preparation method of the medicated wine of described treatment prolapse of lumbar intervertebral disc, comprises the following steps:
Step one, get Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Flos Caryophylli, Rhizoma Alpiniae Officinarum, Rhizoma Cyperi 5-8 part, Caulis Spatholobi, Radix Puerariae, Rhizoma Polygonati, brown sugar (Saccharum Sinensis Roxb.), yellow Semen setariae and the Rhizoma Anemarrhenae respectively according to above-mentioned parts by weight, for subsequent use;
Step 2, got Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and powder of Radix Puerariae are broken into the Chinese medicinal granule that particle diameter is 2.5-5.0mm; Steam 50-70 minute at gained Chinese medicinal granule is placed in 95-100 DEG C, take out and be cooled to 40-45 DEG C, for subsequent use; In got yellow Semen setariae, add its quality 5-10 water doubly, soak 5-8 hour, pull out and drain, for subsequent use;
Step 3, will Radix Aconiti Kusnezoffii Preparata, the Rhizoma Alpiniae Officinarum of 40-45 DEG C be cooled to after steaming, obtain mixture after Flos Caryophylli and Radix Puerariae Chinese medicinal granule and the yellow Semen setariae mix homogeneously after soaking, add distillers yeast and the quality 15-20 water doubly of its quality 2-3% in the resulting mixture, mix homogeneously is placed in ceramic vessel and ferments 2-3 days again, takes out fermented product; In gained fermented product, add its quality 15-20 water doubly, ultrasonic Treatment 2-3 hour under 100-200 kHz power, filters to obtain medicinal liquid A, for subsequent use;
Step 4, got Caulis Spatholobi, Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Cyperi and Rhizoma Anemarrhenae powder are broken into the Chinese medicinal granule that diameter is 3.0-8.0mm; In gained Chinese medicinal granule, add the Bafillus natt of its quality 2-3% and the sterilized water mix homogeneously of quality 2-4%, be placed in ceramic vessel and ferment 2-3 days, take out tunning; In gained tunning, add tunning quality 3-6 Chinese liquor doubly, soak 3-4 hour post-heating to 50-60 DEG C of insulation 2-3 hour, be then cooled to room temperature, cross leaching filtrate, obtain medical liquid B, for subsequent use;
Step 5, by preparation medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C; Got brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan to be fried to coke yellow, joins in medicinal liquid C, is stirred to and dissolves completely, leaves standstill 24-26 hour, filters, and gained medicinal liquid is the medicated wine for the treatment of prolapse of lumbar intervertebral disc.
embodiment 1
Treat a medicated wine for prolapse of lumbar intervertebral disc, the parts by weight of each crude drug of described medicated wine are: Radix Aconiti Kusnezoffii Preparata 25 parts, Radix Angelicae Sinensis 8.3 parts, Flos Caryophylli 8.3 parts, Rhizoma Alpiniae Officinarum 8.3 parts, Rhizoma Cyperi 6 parts, Caulis Spatholobi 6 parts, Radix Puerariae 8 parts, Rhizoma Polygonati 5 parts, brown sugar (Saccharum Sinensis Roxb.) 30 parts, yellow Semen setariae 80 parts and the Rhizoma Anemarrhenae 5 parts.
The preparation method of the medicated wine of described treatment prolapse of lumbar intervertebral disc, comprises the following steps:
Step one, get Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Flos Caryophylli, Rhizoma Alpiniae Officinarum, Rhizoma Cyperi, Caulis Spatholobi, Radix Puerariae, Rhizoma Polygonati, brown sugar (Saccharum Sinensis Roxb.), yellow Semen setariae and the Rhizoma Anemarrhenae respectively according to above-mentioned parts by weight, for subsequent use;
Step 2, got Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and powder of Radix Puerariae are broken into the Chinese medicinal granule that particle diameter is 2.5mm; Steam 50 minutes at gained Chinese medicinal granule is placed in 95 DEG C, take out and be cooled to 40 DEG C, for subsequent use; In got yellow Semen setariae, add the water of its quality 5 times, soak 5 hours, pull out and drain, for subsequent use;
Step 3, will Radix Aconiti Kusnezoffii Preparata, the Rhizoma Alpiniae Officinarum of 40 DEG C be cooled to after steaming, obtain mixture after Flos Caryophylli and Radix Puerariae Chinese medicinal granule and the yellow Semen setariae mix homogeneously after soaking, add the distillers yeast of its quality 2% and the water of quality 15 times in the resulting mixture, mix homogeneously is placed in ceramic vessel fermentation 2 days again, takes out fermented product; In gained fermented product, add the water of its quality 15 times, ultrasonic Treatment 2-3 hour under 100 kHz power, filter to obtain medicinal liquid A, for subsequent use;
Step 4, got Caulis Spatholobi, Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Cyperi and Rhizoma Anemarrhenae powder are broken into the Chinese medicinal granule that diameter is 3.0mm; In gained Chinese medicinal granule, add the Bafillus natt of its quality 2% and the sterilized water mix homogeneously of quality 2%, be placed in ceramic vessel fermentation 2 days, take out tunning; In gained tunning, add the Chinese liquor of tunning quality 3 times, soak post-heating to 50 DEG C insulation in 3 hours 2 hours, be then cooled to room temperature, cross leaching filtrate, obtain medical liquid B, for subsequent use;
Step 5, by preparation medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C; Got brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan to be fried to coke yellow, joins in medicinal liquid C, is stirred to and dissolves completely, leaves standstill 24 hours, filters, and gained medicinal liquid is the medicated wine for the treatment of prolapse of lumbar intervertebral disc.
embodiment 2
Treat a medicated wine for prolapse of lumbar intervertebral disc, the parts by weight of each crude drug of described medicated wine are: Radix Aconiti Kusnezoffii Preparata 20 parts, Radix Angelicae Sinensis 8 parts, Flos Caryophylli 8 parts, Rhizoma Alpiniae Officinarum 8 parts, Rhizoma Cyperi 5 parts, Caulis Spatholobi 5 parts, Radix Puerariae 9 parts, Rhizoma Polygonati 6 parts, brown sugar (Saccharum Sinensis Roxb.) 32 parts, yellow Semen setariae 50 parts and the Rhizoma Anemarrhenae 7 parts.
The preparation method of the medicated wine of described treatment prolapse of lumbar intervertebral disc, comprises the following steps:
Step one, get Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Flos Caryophylli, Rhizoma Alpiniae Officinarum, Rhizoma Cyperi, Caulis Spatholobi, Radix Puerariae, Rhizoma Polygonati, brown sugar (Saccharum Sinensis Roxb.), yellow Semen setariae and the Rhizoma Anemarrhenae respectively according to above-mentioned parts by weight, for subsequent use;
Step 2, got Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and powder of Radix Puerariae are broken into the Chinese medicinal granule that particle diameter is 5.0mm; Steam 70 minutes at gained Chinese medicinal granule is placed in 100 DEG C, take out and be cooled to 45 DEG C, for subsequent use; In got yellow Semen setariae, add the water of its quality 10 times, soak 8 hours, pull out and drain, for subsequent use;
Step 3, will Radix Aconiti Kusnezoffii Preparata, the Rhizoma Alpiniae Officinarum of 45 DEG C be cooled to after steaming, obtain mixture after Flos Caryophylli and Radix Puerariae Chinese medicinal granule and the yellow Semen setariae mix homogeneously after soaking, add the distillers yeast of its quality 2-3% and the water of quality 20 times in the resulting mixture, mix homogeneously is placed in ceramic vessel fermentation 3 days again, takes out fermented product; In gained fermented product, add the water of its quality 20 times, ultrasonic Treatment 2-3 hour under 200 kHz power, filter to obtain medicinal liquid A, for subsequent use;
Step 4, got Caulis Spatholobi, Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Cyperi and Rhizoma Anemarrhenae powder are broken into the Chinese medicinal granule that diameter is 8.0mm; In gained Chinese medicinal granule, add the Bafillus natt of its quality 3% and the sterilized water mix homogeneously of quality 4%, be placed in ceramic vessel fermentation 3 days, take out tunning; In gained tunning, add the Chinese liquor of tunning quality 6 times, soak post-heating to 60 DEG C insulation in 4 hours 3 hours, be then cooled to room temperature, cross leaching filtrate, obtain medical liquid B, for subsequent use;
Step 5, by preparation medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C; Got brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan to be fried to coke yellow, joins in medicinal liquid C, is stirred to and dissolves completely, leaves standstill 26 hours, filters, and gained medicinal liquid is the medicated wine for the treatment of prolapse of lumbar intervertebral disc.
embodiment 3
Treat a medicated wine for prolapse of lumbar intervertebral disc, the parts by weight of each crude drug of described medicated wine are: Radix Aconiti Kusnezoffii Preparata 25 parts, Radix Angelicae Sinensis 10 parts, Flos Caryophylli 10 parts, Rhizoma Alpiniae Officinarum 10 parts, Rhizoma Cyperi 8 parts, Caulis Spatholobi 8 parts, Radix Puerariae 10 parts, Rhizoma Polygonati 8 parts, brown sugar (Saccharum Sinensis Roxb.) 33 parts, yellow Semen setariae 100 parts and the Rhizoma Anemarrhenae 8 parts.
The preparation method of the medicated wine of described treatment prolapse of lumbar intervertebral disc, comprises the following steps:
Step one, get Radix Aconiti Kusnezoffii Preparata, Radix Angelicae Sinensis, Flos Caryophylli, Rhizoma Alpiniae Officinarum, Rhizoma Cyperi, Caulis Spatholobi, Radix Puerariae, Rhizoma Polygonati, brown sugar (Saccharum Sinensis Roxb.), yellow Semen setariae and the Rhizoma Anemarrhenae respectively according to above-mentioned parts by weight, for subsequent use;
Step 2, got Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and powder of Radix Puerariae are broken into the Chinese medicinal granule that particle diameter is 3.5mm; Steam 60 minutes at gained Chinese medicinal granule is placed in 98 DEG C, take out and be cooled to 42 DEG C, for subsequent use; In got yellow Semen setariae, add the water of its quality 8 times, soak 7 hours, pull out and drain, for subsequent use;
Step 3, will Radix Aconiti Kusnezoffii Preparata, the Rhizoma Alpiniae Officinarum of 42 DEG C be cooled to after steaming, obtain mixture after Flos Caryophylli and Radix Puerariae Chinese medicinal granule and the yellow Semen setariae mix homogeneously after soaking, add the distillers yeast of its quality 2.5% and the water of quality 18 times in the resulting mixture, mix homogeneously is placed in ceramic vessel fermentation 2 days again, takes out fermented product; In gained fermented product, add the water of its quality 18 times, ultrasonic Treatment 2-3 hour under 150 kHz power, filter to obtain medicinal liquid A, for subsequent use;
Step 4, got Caulis Spatholobi, Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Cyperi and Rhizoma Anemarrhenae powder are broken into the Chinese medicinal granule that diameter is 3.5mm; In gained Chinese medicinal granule, add the Bafillus natt of its quality 2.5% and the sterilized water mix homogeneously of quality 3%, be placed in ceramic vessel fermentation 2 days, take out tunning; In gained tunning, add the Chinese liquor of tunning quality 5 times, soak post-heating to 55 DEG C insulation in 3 hours 2 hours, be then cooled to room temperature, cross leaching filtrate, obtain medical liquid B, for subsequent use;
Step 5, by preparation medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C; Got brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan to be fried to coke yellow, joins in medicinal liquid C, is stirred to and dissolves completely, leaves standstill 25 hours, filters, and gained medicinal liquid is the medicated wine for the treatment of prolapse of lumbar intervertebral disc.
One, clinical testing data
1, experimental subject: the patient 300 suffering from prolapse of lumbar intervertebral disc on inspection, wherein lumbago symptom is lighter, protruding type mainly takes place frequently lumbago or increase the weight of and accompany the patient 60 of lower limb radiating pain, prolapsus sequestered lumbago takes place frequently, increase the weight of at nightfall, generally with the patient 110 of serious lower limb radiating pain, lumbago takes place frequently, increase the weight of, generally with serious lower limb radiating pain person 140 at nightfall; There is cauda equina nerve symptom in some patients, or sensory disturbance and muscular strength decline.
2, Therapeutic Method: the medicated wine of oral medication prolapse of lumbar intervertebral disc, every day three times, each 5-15 milliliter, (medicine) being taken before meal is used.Simultaneously with the appropriate affected part of exterior coating of this medicated wine, every day 2-3 time; It within 7 days, is 1 course for the treatment of.
3, evaluation criterion is treated:
Cure: CT shows the healing of lumbar vertebra vertebra dish annulus fibrosus portion, and top layer is complete, and vertebral pulp is well clear with intraspinal tube physiological level position, smooth surface, pain disappearance;
Effective: between lumbar vertebra vertebra dish, Anular disruption degree is significantly taken on a new look, part healing, vertebral pulp is dashed forward to canalis spinalis phenomenon and is alleviated in various degree, and posterior longitudinal ligament covers completely, and surface is more smooth, and lumbago symptom and lower limb radiating pain symptom disappear substantially;
Effective: to meet healing or effective standard.
Invalid: CT shows lumbar intervertebral disc without significant change.
4, therapeutic effect: 300 patients that the present invention treats, wherein cures patients with lumbar disc herniation 195, effective 72 examples, and total effective rate reaches 89%; Result shows that the present invention treats the medicated wine of prolapse of lumbar intervertebral disc, and formula and prescription is reasonable, remarkable to Lumbar Intervertebral Disc.
Two, model case:
1, poplar, man, 50 years old, lumbago four months (increasing the weight of month), when being admitted to hospital, CT shows prolapse of lumbar intervertebral disc, and middle lumbago symptom is comparatively light, and protruding type mainly takes place frequently lumbago or increase the weight of and accompany lower limb radiating pain; The medicated wine of oral medication prolapse of lumbar intervertebral disc, every day three times, each 5-15 milliliter, (medicine) being taken before meal is used.And with the appropriate affected part of exterior coating of medicated wine for the treatment of prolapse of lumbar intervertebral disc, every day 2-3 time; Two courses for the treatment of of continuous treatment; Lumbago remission, after treating for three courses for the treatment of continuously, lumbago disappears, and continuous clothes are to five courses for the treatment of, and check CT joint of lumbar vertebra, vertebra dish fibrous ring top layer is complete, and physiological level position is well clear, so far without recurring.
2, grandson, female, 43 years old, lumbago more than 2 years (increasing the weight of three months), at nightfall and overwork postemphasis especially obvious, numbness of lower limbs pain, bend over and action of going down on one's knees slightly limited, CT examination display prolapse of lumbar intervertebral disc, the medicated wine of oral medication prolapse of lumbar intervertebral disc, every day three times, each 5-15 milliliter, (medicine) being taken before meal is used.And with the appropriate affected part of exterior coating of medicated wine for the treatment of prolapse of lumbar intervertebral disc, every day 2-3 time; Two courses for the treatment of of continuous treatment; Lumbago remission, continuously after three courses for the treatment of of treatment, lumbago disappears, continuously continuous treatment five course for the treatment of, check CT display, intervertebral Anular disruption degree is significantly improved, and portion heals, and vertebral pulp is longitudinally outstanding slightly to bounce back, posterior longitudinal ligament covers completely, smooth surface, and miscellaneous function is taken exercise, freely flexibly.Continuous treatment was consolidated to nine courses for the treatment of, and after advising it to leave hospital, wind sheltering is trembled with fear, careful work, so far without recurrence.
3, willow, man, 65 years old, the lumbago that takes place frequently 7 years, two numbness of lower limbs, thigh lateral muscle group and gluteus maximus have an intense pain, autonomous Disability, bimester before increase the weight of, the CT that is admitted to hospital shows prolapse of lumbar intervertebral disc, the medicated wine of oral medication prolapse of lumbar intervertebral disc, every day three times, each 5-15 milliliter, (medicine) being taken before meal is used.And with the appropriate affected part of exterior coating of medicated wine for the treatment of prolapse of lumbar intervertebral disc, every day 2-3 time; Two courses for the treatment of of continuous treatment; Lumbago remission, continuously after three courses for the treatment of of treatment, lumbago disappears, continuously continuous treatment seven course for the treatment of, check CT display, intervertebral Anular disruption degree is significantly improved, and portion heals, and vertebral pulp is longitudinally outstanding slightly to bounce back, posterior longitudinal ligament covers completely, smooth surface, and miscellaneous function is taken exercise, freely flexibly.Continuous treatment was consolidated to nine courses for the treatment of, and after advising it to leave hospital, wind sheltering is trembled with fear, careful work, uncomfortable with examining, so far without recurrence.
Bafillus natt of the present invention is common Bafillus natt strain, buys obtain by market.

Claims (2)

1. treat a preparation method for the medicated wine of prolapse of lumbar intervertebral disc, it is characterized in that: comprise the following steps:
Step one, get Radix Aconiti Kusnezoffii Preparata 20-25 part, Radix Angelicae Sinensis 8-10 part, Flos Caryophylli 8-10 part, Rhizoma Alpiniae Officinarum 8-10 part, Rhizoma Cyperi 5-8 part, Caulis Spatholobi 5-8 part, Radix Puerariae 8-10 part, Rhizoma Polygonati 5-8 part, brown sugar (Saccharum Sinensis Roxb.) 30-33 part, yellow Semen setariae 50-100 part and Rhizoma Anemarrhenae 5-8 part respectively according to parts by weight, for subsequent use;
Step 2, got Radix Aconiti Kusnezoffii Preparata, Rhizoma Alpiniae Officinarum, Flos Caryophylli and powder of Radix Puerariae are broken into the Chinese medicinal granule that particle diameter is 2.5-5.0mm; Steam 50-70 minute at gained Chinese medicinal granule is placed in 95-100 DEG C, take out and be cooled to 40-45 DEG C, for subsequent use; In got yellow Semen setariae, add its quality 5-10 water doubly, soak 5-8 hour, pull out and drain, for subsequent use;
Step 3, will Radix Aconiti Kusnezoffii Preparata, the Rhizoma Alpiniae Officinarum of 40-45 DEG C be cooled to after steaming, obtain mixture after Flos Caryophylli and Radix Puerariae Chinese medicinal granule and the yellow Semen setariae mix homogeneously after soaking, add distillers yeast and the 15-20 water doubly of its quality 2-3% in the resulting mixture, mix homogeneously is placed in ceramic vessel and ferments 2-3 days again, takes out fermented product; In gained fermented product, add its quality 15-20 water doubly, ultrasonic Treatment 2-3 hour under 100-200 kHz power, filters to obtain medicinal liquid A, for subsequent use;
Step 4, got Caulis Spatholobi, Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Cyperi and Rhizoma Anemarrhenae powder are broken into the Chinese medicinal granule that diameter is 3.0-8.0mm; In gained Chinese medicinal granule, add the Bafillus natt of its quality 2-3% and the sterilized water mix homogeneously of 2-4%, be placed in ceramic vessel and ferment 2-3 days, take out tunning; In gained tunning, add tunning quality 3-6 Chinese liquor doubly, soak 3-4 hour post-heating to 50-60 DEG C of insulation 2-3 hour, be then cooled to room temperature, cross leaching filtrate, obtain medical liquid B, for subsequent use;
Step 5, by gained medicinal liquid A and medical liquid B mixing, obtain medicinal liquid C; Got brown sugar (Saccharum Sinensis Roxb.) is placed in iron pan to be fried to coke yellow, joins in medicinal liquid C, is stirred to and dissolves completely, leaves standstill 24-26 hour, filters, and namely gained medicinal liquid prepares the medicated wine for the treatment of prolapse of lumbar intervertebral disc.
2. the preparation method of the medicated wine for the treatment of prolapse of lumbar intervertebral disc as claimed in claim 1, is characterized in that: in step one the parts by weight of each crude drug of wine of getting it filled be: Radix Aconiti Kusnezoffii Preparata 25 parts, Radix Angelicae Sinensis 8.3 parts, Flos Caryophylli 8.3 parts, Rhizoma Alpiniae Officinarum 8.3 parts, Rhizoma Cyperi 6 parts, Caulis Spatholobi 6 parts, Radix Puerariae 8 parts, Rhizoma Polygonati 5 parts, brown sugar (Saccharum Sinensis Roxb.) 30 parts, yellow Semen setariae 80 parts and the Rhizoma Anemarrhenae 5 parts.
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Citations (2)

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Publication number Priority date Publication date Assignee Title
JP2003159030A (en) * 2001-11-28 2003-06-03 Joyaku Kenkyusho:Kk Food composition
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Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003159030A (en) * 2001-11-28 2003-06-03 Joyaku Kenkyusho:Kk Food composition
CN103484288A (en) * 2013-08-19 2014-01-01 刘军科 Method for improving effect of medicinal liquor and probiotic composition

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Title
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