CN107362227A - A kind of Chinese medicine composition and its application in the medicine for preparing prevention and treatment osteoproliferation - Google Patents

A kind of Chinese medicine composition and its application in the medicine for preparing prevention and treatment osteoproliferation Download PDF

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Publication number
CN107362227A
CN107362227A CN201610312377.XA CN201610312377A CN107362227A CN 107362227 A CN107362227 A CN 107362227A CN 201610312377 A CN201610312377 A CN 201610312377A CN 107362227 A CN107362227 A CN 107362227A
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parts
chinese medicine
medicine composition
root
weight
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郭艳玲
杨志琴
李星
庞军
张婧
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YAN'AN PEOPLE'S HOSPITAL
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YAN'AN PEOPLE'S HOSPITAL
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
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    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
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    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716Clematis (leather flower)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger

Abstract

The invention provides a kind of Chinese medicine composition, application of the described Chinese medicine composition in the medicine for preparing prevention and treatment osteoproliferation;Described Chinese medicine composition includes the composition of following parts by weight, 20 25 parts of the root of herbaceous peony, 10 20 parts of the root of Chinese clematis, 10 20 parts of the bark of eucommia, 10 20 parts of levisticum, 10 20 parts of Ligusticum wallichii, 10 20 parts of cultivated land, 10 20 parts of Radix Angelicae Sinensis, 15 20 parts of the root of kudzu vine, 4 10 parts of asarum, 35 parts of radix glycyrrhizae;Chinese medicine composition of the present invention treats 99 sufferers of osteoporosis face altogether, and tested patients without serious adverse reaction, go clinical symptoms to be effectively improved, with reference to efficacy assessment standard evaluation patient clinical curative effect, wherein curing 37, effective 49,13 invalid, and clinical effective rate is up to 86.87%.

Description

A kind of Chinese medicine composition and its application in the medicine for preparing prevention and treatment osteoproliferation
Technical field
The present invention relates to field of Chinese medicinal composition, more particularly to a kind of Chinese medicine for preventing and treating osteoproliferation Composition.
Background technology
Osteoproliferation is also spur, and academic noun is bone wart (Bone Spur), be joint because of various reasons Cause the abrasion of cartilage, destroy, and facilitate repairing, hardening and the hyperplasia of bone in itself, be a kind of natural Aging phenomenon, general long spur means that the bone of this person enters the ageing step.However, spur is not The patent of the elderly, due to work, many people must sitting, long station, along with posture not just Really, it is easy to make vertebra that degradation phenomena occur ahead of time, and induce the generation of spur.Spur be most commonly in knee, The joints such as hip, lumbar vertebrae, cervical vertebra, elbow.
Said from traditional Chinese medical science angle, spur disease belongs to " bi Zheng " category of the traditional Chinese medical science, also known as " heumatism ".The traditional Chinese medical science thinks this disease It is relevant with wound, strain, obstruction of collaterals by blood stasis, the damp evil that is affected by the cold, phlegm resistance, caused by liver and kidney deficiency etc..Its Symptom is mainly manifested in the following aspects:1st, pathology, irregular cartilage lesions, in heavy burden region Subchondral bone sclerosis, tumour, edge osteophytosis, metaphysis blood flow increase and different degrees of synovial membrane It is scorching;2nd, histology, early stage cartilage surface fragmentation, the proliferation of chondrocytes, cartilage surface is longitudinally split, crystallizes Deposition, while there is repair of cartilage, osteophytosis;There is the thorough destruction of cartilage in late period, shows as Focal osteonecrosis under cartilage hardening, cartilage disappearance and cartilage;3rd, biomethanics, articular cartilage are stretched Extensional, compressive resistance, anti-shearing force and cartilage permeability reduce.The increase of cartilage moisture, excessive swelling are soft Bone sending down the fishbone is hard;4th, biochemical change, the content (concentration) of proteoglycans decline, its molecular size and aggregation Degree changes, and abnormal change occur in size, arrangement and the synthesis of Matrix protein and degraded of collagenous fibres Become;5th, nutrition, the basic reason of spur is calcium deficiency.
Osteoproliferation is one of current cureless disease, although although hyperosteogeny is unlike cancer It is equally fatal, but patient must endure the sensation of various numb pains for a long time, be a kind of very painful disease. The disease is that one kind is accumulated over a long period potential disease simultaneously, and with advancing age, the cartilage in joint gradually moves back Change, the elasticity reduction of cell, Bones and joints are unconsciously being worn, especially the larger neck of activity, Waist, knee joint, heel, the articular cartilage of damage are difficult to repair when no blood vessel supplies nutrition, this When articular cartilage peripheral blood recycle ratio it is more vigorous, just occur compensatory cartilage increase, this is The predecessor of osteoproliferation, the cartilage of hyperplasia is again by calcification over time, and here it is osteoproliferation.Hyperostosis Phase non-evident sympton before death, it can not accomplish to prevent in time, pathological state has been transformed into once there is symptom Can teratogenesis or cause paralysis.
The treatment to osteoproliferation combines instrument more or performed the operation in the prior art, on the one hand treatment effect Fruit can not ensure that another aspect operation risk is larger.Therefore, being badly in need of one kind effectively can prevent and control Treat the medicine of osteoproliferation.
The content of the invention
In view of this, it is an object of the invention to provide one kind can effectively prevent and treat osteoproliferation Chinese medicine composition.
In order to realize foregoing invention purpose, the present invention provides following technical scheme:
The invention provides a kind of Chinese medicine composition, include the composition of following parts by weight, root of herbaceous peony 20-25 parts, Root of Chinese clematis 10-20 parts, bark of eucommia 10-20 parts, levisticum 10-20 parts, Ligusticum wallichii 10-20 parts, cultivated land 10-20 Part, Radix Angelicae Sinensis 10-20 parts, root of kudzu vine 15-20 parts, asarum 4-10 parts, radix glycyrrhizae 3-5 parts.
Preferably, the composition of following parts by weight, 22.5 parts of the root of herbaceous peony, 15 parts of the root of Chinese clematis, the bark of eucommia 15 are included Part, 15 parts of levisticum, 15 parts of Ligusticum wallichii, 15 parts of cultivated land, 15 parts of Radix Angelicae Sinensis, 17.5 parts of the root of kudzu vine, asarum 7 Part, 4 parts of radix glycyrrhizae.
Preferably, the composition of following parts by weight, Radix Astragali 15-20 parts, Radix Codonopsis 15-20 parts are included.
Preferably, the composition of following parts by weight, Fructus Aurantii 10-15 parts, red sage root 10-15 parts, corydalis tuber 9-12 are included Part.
Preferably, the composition of following parts by weight, cassia twig 10-15 parts, Chinese ephedra 6-8 parts, rhizoma zingiberis are included 6-8 parts, earthworm 9-12 parts.
Preferably, the composition of following parts by weight, matrimony vine 10-15 parts, radix bupleuri 10-15 parts are included.
Present invention also offers described Chinese medicine composition in the medicine for preparing prevention and treatment osteoproliferation Application.
Beneficial effects of the present invention:The invention provides a kind of Chinese medicine composition, including following parts by weight Composition, root of herbaceous peony 20-25 parts, root of Chinese clematis 10-20 parts, bark of eucommia 10-20 parts, levisticum 10-20 parts, Ligusticum wallichii 10-20 parts, cultivated land 10-20 parts, Radix Angelicae Sinensis 10-20 parts, root of kudzu vine 15-20 parts, asarum 4-10 parts, radix glycyrrhizae 3-5 parts.99 sufferers of osteoporosis face, tested patients are treated using Chinese medicine composition provided by the invention altogether Without serious adverse reaction, go clinical symptoms to be effectively improved, suffer from reference to efficacy assessment standard evaluation Person's clinical efficacy, wherein curing 37, effective 49,13 invalid, and clinical effective rate is up to 86.87%.
Embodiment
The invention provides a kind of Chinese medicine composition, include the composition of following parts by weight, root of herbaceous peony 20-25 parts, Root of Chinese clematis 10-20 parts, bark of eucommia 10-20 parts, levisticum 10-20 parts, Ligusticum wallichii 10-20 parts, cultivated land 10-20 Part, Radix Angelicae Sinensis 10-20 parts, root of kudzu vine 15-20 parts, asarum 4-10 parts, radix glycyrrhizae 3-5 parts.
In the present invention, the root of herbaceous peony:Bitter, acid, is slightly cold, Return liver, the spleen channel;Effect:The moon, soft liver are held back in blood-nourishing Analgesic, suppressing liver-YANG;Cure mainly:For irregular menstruation, uterine bleeding, abnormal sweating, gastral cavity abdomen shoot, pain over the hypochondriac region, Four limbs contraction pain, dizziness of having a headache;The parts by weight of the heretofore described root of herbaceous peony are preferably 20-25 parts, more Preferably 22.5 parts.
In the present invention, the described root of Chinese clematis:It is pungent, salty, temperature;Return bladder warp, Liver Channel;Effect:Dispel Wind dehumidifies, and removes obstruction in channels to relieve pain;Cure mainly:For arthralgia pain due to rheumatism, extremity numbness, muscle arteries and veins contraction, joint stuffiness, Bone is choked with sobs larynx;The parts by weight of the heretofore described root of Chinese clematis are preferably 10-20 parts, more preferably 15 parts.
The bark of eucommia described in Chinese medicine composition of the present invention:It is sweet, temperature;Return liver and kidney channel;Effect:Tonifying liver Kidney, strengthening the bones and muscles are antiabortive;For lumbago due to the kidney deficiency, muscles and bones is powerless, blood leaking in gestation, fetal irritability;High blood Pressure;The heretofore described bark of eucommia is preferably 10-20 parts, more preferably 15 parts.
Levisticum described in Chinese medicine composition of the present invention:It is pungent, bitter, tepor;Return kidney, bladder warp;Effect: Dispelling wind and eliminating dampness, numbness relieving and pain relieving;For wind-cold-dampness arthralgia, lumbocrural pain, few the moon volt wind headache;In the present invention Described levisticum is preferably 10-20 parts, more preferably 15 parts.
Ligusticum wallichii described in Chinese medicine composition of the present invention:It is pungent, temperature, Return liver, courage, the heart channel of Hang-Shaoyin;Effect:It is living Blood gas, wind-expelling pain-stopping, promote breath and open depression;For irregular menstruation, dysmenorrhoea, Amenorrhea, dizziness of having a headache mesh is dark, Wind-cold-dampness arthralgia, extremity numbness, ulcer sores;Heretofore described rhizome of chuanxiong is preferably 10-20 parts, More preferably 15 parts.
Cultivated land described in Chinese medicine composition of the present invention:It is sweet, tepor;Return liver and kidney channel;Effect:Enrich blood Yin-nourishing, life essence-filling, marrow-benefitting;For the evil Sheng of blood-head, syndrome of yin deficiency and depletion of fluid, blood-head impairment of yin and fever due to yin deficiency person;This Cultivated land described in invention is preferably 10-20 parts, more preferably 15 parts.
Radix Angelicae Sinensis described in Chinese medicine composition of the present invention:It is sweet, pungent, warm;Return liver, the heart, the spleen channel;Enrich blood; Promoting blood circulation;Menstruction regulating and pain relieving, moisturize laxation;For intestines are dry and shit is difficult, weight, ulcer sores, falls and flutters damage after dysentery characterized by blood in the stool Wound;Heretofore described Radix Angelicae Sinensis is preferably 10-20 parts, more preferably 15 parts.
The root of kudzu vine described in Chinese medicine composition of the present invention:It is sweet, pungent, put down;Returns spleen, stomach, lung, bladder warp; Effect:Expelling pathogenic factors from muscles and skin is brought down a fever, and is delivered and is examined, and is promoted the production of body fluid to quench thirst, Shengyang Zhixie;Generated heat for exterior syndrome, rigid neck and back Bitterly, measles without adequate eruption, pyreticosis is thirsty, and the deficiency of Yin is quenched one's thirst, and heat is purged heat dysentery, splenasthenic diarrhea;It is heretofore described The root of kudzu vine be preferably 15-20 parts, more preferably 17.5 parts.
Asarum described in Chinese medicine composition of the present invention:It is pungent, temperature;The thoughts of returning home, lung, kidney channel;Relieving exterior syndrome and dispelling cold, Wind-expelling pain-stopping, sensible, Wenfei of drink;For anemofrigid cold, have a headache, toothache, runny nose of having a stuffy nose, allergic rhinitis, Nasosinusitis, arthralgia pain due to rheumatism, sputum cough;Heretofore described asarum is preferably 4-10 parts, more preferably For 7 parts.
Radix glycyrrhizae described in Chinese medicine composition of the present invention:It is sweet, flat, enter the heart, lung, spleen, stomach;Effect:Mend Spleen QI invigorating, expelling phlegm and arresting coughing, relieving spasm to stop pain, clearing heat and detoxicating, coordinating the drug actions of a prescription;Fever and chills perverse trend, infirmities and diseases, Energy moistening lung removing toxic substances, and middle emergency;Radix glycyrrhizae of the present invention is preferably 3-5 parts, more preferably 4 parts.
Each component compatibility in Chinese medicine composition of the present invention, promoting blood circulation is played, relieved pain, changed and become silted up, stimulate the menstrual flow
Network is walked, is had one's ideas straightened out deep, expelling wind and clearing away cold and other effects, and acted on by the channel tropism of medicine and conditioning engine body Equilibrium between yin and yang, permeate in epidermis, stimulate nerve endings, promote local blood microcirculation, strengthen the body resistance to consolidate the constitution, Improve constitution, fundamentally, it is comprehensive for spur pathogenic characteristic and play curative effect, improve perilesional Histotrophic nutrition, play a part of repairing osteopathy tissue, be finally reached therapeutic purposes.
Chinese medicine composition provided by the invention preferably also includes the Radix Astragali and Radix Codonopsis, in above-mentioned Chinese medicine composition Chinese medicine composition obtained by the addition Radix Astragali and Radix Codonopsis also has the effect of regulation deficiency of vital energy deficiency of blood.
The heretofore described Radix Astragali:It is sweet, tepor;Return lung, spleen, liver and kidney channel;Effect, QI invigorating are solid Table, arrest sweating admittedly take off, torr sore myogenic, inducing diuresis for removing edema;The preferable addition of the Radix Astragali of the present invention is 15~20 Part, more preferably 17.5 parts.
In the present invention, described Radix Codonopsis:It is sweet, put down;Returns spleen, lung channel;Effect:Tonifying middle-Jiao and Qi, it is good for Spleen benefit lung;For spleen and lung weakness, shortness of breath palpitations, anorexia and loose stool, empty cough, Heat Diabetes are breathed heavily;It is described The addition of Radix Codonopsis be preferably 15-20 parts, more preferably 17.5 parts.
Chinese medicine composition provided by the invention preferably also includes Fructus Aurantii, the red sage root and corydalis tuber, resulting Chinese medicine Composition also has the effect of regulation qi depression to blood stasis.
In the present invention, described Fructus Aurantii:It is bitter, pungent, sour, temperature;Returns spleen, stomach;Effect:Qi-regulating In width, the stagnant dissipate-swelling of row;For the chest side of body stagnation of the circulation of vital energy, turgor pain, accumulation of food in the stomach and intes tine due to indigestion, stop in phlegm and retained fluid;Gastroptosis, Prolapse of the anus, sub-official prolapses;The preferable addition of heretofore described Fructus Aurantii is 10-15 parts, more preferably 12.5 parts.
In the present invention, the described red sage root:Hardship, it is slightly cold;The thoughts of returning home, Liver Channel;Effect:Promoting blood circulation for regulating menstruation, Cool blood to disappear carbuncle, clearing away the heart fire and tranquillizing;The addition of the heretofore described red sage root is preferably 10-15 parts, more excellent Choosing for 12.5 parts.
In the present invention, described corydalis tuber:Acrid, bitter, warm;Return liver, spleen, the heart channel of Hang-Shaoyin;Effect:Promoting blood circulation, Promoting the circulation of qi, analgesic;It is mainly used in all pain cards of stagnation of QI and blood;The addition of heretofore described corydalis tuber is preferred For 9~12 parts, more preferably 10.5 parts.
Chinese medicine composition provided by the invention preferably also includes cassia twig, Chinese ephedra, rhizoma zingiberis and earthworm institute, obtains Chinese medicine composition also have regulation chill rheumatism the effect of.
Heretofore described cassia twig:Xin Gan, temperature;The thoughts of returning home, lung, bladder warp;Effect:With cold dispelling Inducing diaphoresis, warming meridians and promoting circulation of qi, activating YANG and prormoting functioning of QI;For chill table disease, numbness and ache of cold dampness, peripheral coldness, Amenorrhea pain Through storing blood, the obstruction of qi in the chest, palpitaition, phlegm and retained fluid, difficult urination;Heretofore described cassia twig preferably adds Measure as 10-15 parts, more preferably 12.5 parts.
Heretofore described Chinese ephedra:Pungent, slight bitter, temperature;Return lung, bladder warp;Effect:Sweating cold dispelling,
Freeing lung and relieving asthma, inducing diuresis for removing edema;Uncomfortable in chest to breath with cough for anemofrigid cold, geomantic omen edema, bronchus is roared Asthma;Heretofore described Chinese ephedra is preferably 6~8 parts, more preferably 7 parts.
Rhizoma zingiberis of the present invention:It is pungent, heat;Returns spleen, stomach, the heart, lung channel;Effect:Warming spleen and stomach for dispelling cold, Back to Yang Tongmai, eliminating dampness dissolving phlegm;For coldness and pain in the epigastrium, vomiting and diarrhea, cold weak pulse of limb, phlegm and retained fluid cough and asthma;This The addition of rhizoma zingiberis described in invention is preferably 6~8 parts, more preferably 7 parts.
Heretofore described earthworm:It is salty, tremble with fear;Return liver, spleen, bladder warp;Effect:Clear gesture stops convulsion, It is calming the liver to stop the wind, clearing and activating the channels and collaterals, diuresis of relievining asthma;For pyreticosis generate heat mad dry, twitch, the liver-yang headache, Hemiplegia, arthralgia pain due to rheumatism, dyspnea and cough due to lung-heat, urinary obstruction;The addition of heretofore described earthworm Preferably 9~12 parts, more preferably 10.5 parts.
Chinese medicine composition provided by the invention preferably also includes matrimony vine and radix bupleuri, resulting Chinese medicine composition Also there is the effect of regulation liver-kidney deficiency.
Heretofore described matrimony vine:It is flat, it is sweet;Enter Liver Channel, kidney channel, lung channel;Effect:It is nourishing liver and kidney, Benefiting shrewd head;For consumption consumptive loss, soreness of waist and knee joint, dizziness and tinnitus, Heat Diabetes, blood deficiency chlorosis, mesh Dusk is not clear;The addition of heretofore described matrimony vine is preferably 10~15 parts, more preferably 12.5 Part.
Heretofore described radix bupleuri:It is flat, it is sweet;Enter Liver Channel, kidney channel, lung channel;Effect:It is nourishing liver and kidney, Benefiting shrewd head;For consumption consumptive loss, soreness of waist and knee joint, dizziness and tinnitus, Heat Diabetes, blood deficiency chlorosis, mesh Dusk is not clear;The addition of heretofore described radix bupleuri is preferably 10~15 parts, more preferably 12.5 Part.
The unit of the parts by weight of heretofore described Chinese medicine composition preferably gram;It is heretofore described Chinese medicine composition application method preferably pharmaceutical composition is directly mixed after with being decocted in water for oral dose, 1 dose/ Day, 2 times/day, 200~300ml, takes in the morning and evening every time;It is aided with salt bag hot compress simultaneously, applies once every night, One time 10 minutes, 15 days courses for the treatment of, 3 courses for the treatment of altogether.
Present invention also offers described Chinese medicine composition in the medicine for preparing prevention and treatment osteoproliferation Application
Chinese medicine composition provided by the invention is described in detail with reference to embodiment, but can not They are interpreted as limiting the scope of the present invention.
Embodiment 1
A kind of Chinese medicine composition for treating osteoproliferation includes the composition of following parts by weight:22.5 parts of the root of herbaceous peony, 15 parts of the root of Chinese clematis, 15 parts of the bark of eucommia, 15 parts of levisticum, 15 parts of Ligusticum wallichii, 15 parts of cultivated land, 15 parts of Radix Angelicae Sinensis, 17.5 parts of the root of kudzu vine, 7 parts of asarum, 4 parts of radix glycyrrhizae.
The application method of described Chinese medicine composition:With being decocted in water for oral dose after pharmaceutical composition is directly mixed, 1 dose / day, 2 times/day, each 250ml, take in the morning and evening;It is aided with salt bag hot compress simultaneously, 1 kilogram of crude salt is existed It is inner to make and (fry to salt and black) cloth bag (long 20cm, wide 10cm) that loading is sewed it up in iron pan popular, every night Apply once, one time 10 minutes, 15 days courses for the treatment of, altogether 3 courses for the treatment of.
The statistics of the effect of described Chinese medicine composition, 99 spur patients are treated altogether and take embodiment 1 Traditional Chinese medicine composition for treating after, without serious adverse reaction, go clinical symptoms to be effectively improved, join Patient clinical curative effect is evaluated according to efficacy assessment standard, wherein curing 37, effective 49,13 are invalid, Clinical effective rate is up to 86.87%.
Hyperostosis criterion of therapeutical effect
Clinical recovery:Clinical symptom disappearance, local movement freely, recover normal work, x-ray check hyperostosis Life does not have growth, and follow-up is without recurrence after 1 year.
It is effective:Clinical symptoms are disappeared substantially, and local movement is limited without obvious, can recover to work originally.
Effectively:Clinical symptoms are obviously improved, tired or may occur in which symptom after catching cold, but have been mitigated earlier above, can Participate in lighter work.
It is invalid:2~3 courses for the treatment of are treated in medication, and clinical symptoms improve unobvious, and joint movement disorder is unchanged, Very then aggravate.
Embodiment 2
A kind of Chinese medicine composition for treating osteoproliferation includes the composition of following parts by weight:22.5 parts of the root of herbaceous peony, 15 parts of the root of Chinese clematis, 15 parts of the bark of eucommia, 15 parts of levisticum, 15 parts of Ligusticum wallichii, 15 parts of cultivated land, 15 parts of Radix Angelicae Sinensis, 17.5 parts of the root of kudzu vine, 7 parts of asarum, 4 parts of radix glycyrrhizae, 17.5 parts of the Radix Astragali, 17.5 parts of Radix Codonopsis.
Described medicine can also adjust the deficiency of vital energy deficiency of blood.
By after described pharmaceutical composition directly mixing with being decocted in water for oral dose, 1 dose/day, 2 times/day, each 250ml, Take in the morning and evening;Be aided with salt bag hot compress simultaneously, crude salt made in iron pan for 1 kilogram popular (stir-fry to salt blacks) It is inner to load the cloth bag (long 20cm, wide 10cm) sewed it up, applies once every night, one time 10 minutes, 15 Its course for the treatment of, altogether 3 courses for the treatment of.
Embodiment 3
A kind of Chinese medicine composition for treating osteoproliferation includes the composition of following parts by weight:22.5 parts of the root of herbaceous peony, 15 parts of the root of Chinese clematis, 15 parts of the bark of eucommia, 15 parts of levisticum, 15 parts of Ligusticum wallichii, 15 parts of cultivated land, 15 parts of Radix Angelicae Sinensis, 17.5 parts of the root of kudzu vine, 7 parts of asarum, 4 parts of radix glycyrrhizae, 12.5 parts of Fructus Aurantii, 12.5 parts of the red sage root, corydalis tuber 10.5 Part.
Described Chinese medicine composition can also adjust qi depression to blood stasis.
By after described pharmaceutical composition directly mixing with being decocted in water for oral dose, 1 dose/day, 2 times/day, each 250ml, Take in the morning and evening;Be aided with salt bag hot compress simultaneously, crude salt made in iron pan for 1 kilogram popular (stir-fry to salt blacks) It is inner to load the cloth bag (long 20cm, wide 10cm) sewed it up, applies once every night, one time 10 minutes, 15 Its course for the treatment of, altogether 3 courses for the treatment of.
Embodiment 4
A kind of Chinese medicine composition for treating osteoproliferation includes the composition of following parts by weight:22.5 parts of the root of herbaceous peony, 15 parts of the root of Chinese clematis, 15 parts of the bark of eucommia, 15 parts of levisticum, 15 parts of Ligusticum wallichii, 15 parts of cultivated land, 15 parts of Radix Angelicae Sinensis, 17.5 parts of the root of kudzu vine, 7 parts of asarum, 4 parts of radix glycyrrhizae, 12.5 parts of cassia twig, 7 parts of Chinese ephedra, 7 parts of rhizoma zingiberis, ground 10.5 parts of dragon.
Described Chinese medicine composition can also adjust chill rheumatism.
By after described pharmaceutical composition directly mixing with being decocted in water for oral dose, 1 dose/day, 2 times/day, each 250ml, Take in the morning and evening;Be aided with salt bag hot compress simultaneously, crude salt made in iron pan for 1 kilogram popular (stir-fry to salt blacks) It is inner to load the cloth bag (long 20cm, wide 10cm) sewed it up, applies once every night, one time 10 minutes, 15 Its course for the treatment of, altogether 3 courses for the treatment of.
Embodiment 5
A kind of Chinese medicine composition for treating osteoproliferation includes the composition of following parts by weight:22.5 parts of the root of herbaceous peony, 15 parts of the root of Chinese clematis, 15 parts of the bark of eucommia, 15 parts of levisticum, 15 parts of Ligusticum wallichii, 15 parts of cultivated land, 15 parts of Radix Angelicae Sinensis, 17.5 parts of the root of kudzu vine, 7 parts of asarum, 4 parts of radix glycyrrhizae, 12.5 parts of matrimony vine, 12.5 parts of radix bupleuri.
Described Chinese medicine composition can also adjust liver-kidney deficiency.
By after described pharmaceutical composition directly mixing with being decocted in water for oral dose, 1 dose/day, 2 times/day, each 250ml, Take in the morning and evening;Be aided with salt bag hot compress simultaneously, crude salt made in iron pan for 1 kilogram popular (stir-fry to salt blacks) It is inner to load the cloth bag (long 20cm, wide 10cm) sewed it up, applies once every night, one time 10 minutes, 15 Its course for the treatment of, altogether 3 courses for the treatment of.
As seen from the above embodiment, Chinese medicine composition provided by the invention has promoting blood circulation, analgesic, changes and becomes silted up, Stimulate the menstrual flow away network, has one's ideas straightened out deep, expelling wind and clearing away cold and other effects, can conditioning engine body equilibrium between yin and yang, permeate in epidermis, Nerve endings is stimulated, promotes local blood microcirculation, strengthens the body resistance to consolidate the constitution, improves constitution, fundamentally, entirely Bearing bar plays curative effect to spur pathogenic characteristic, and clinical effective rate is up to 86.87%.
Described above is only the preferred embodiment of the present invention, it is noted that for the general of the art For logical technical staff, under the premise without departing from the principles of the invention, some improvement and profit can also be made Decorations, these improvements and modifications also should be regarded as protection scope of the present invention.

Claims (7)

1. a kind of Chinese medicine composition, include the component of following parts by weight, root of herbaceous peony 20-25 parts, root of Chinese clematis 10-20 Part, bark of eucommia 10-20 parts, levisticum 10-20 parts, Ligusticum wallichii 10-20 parts, cultivated land 10-20 parts, Radix Angelicae Sinensis 10-20 Part, root of kudzu vine 15-20 parts, asarum 4-10 parts, radix glycyrrhizae 3-5 parts.
2. Chinese medicine composition according to claim 1, it is characterised in that include the composition of following parts by weight, 22.5 parts of the root of herbaceous peony, 15 parts of the root of Chinese clematis, 15 parts of the bark of eucommia, 15 parts of levisticum, 15 parts of Ligusticum wallichii, 15 parts of cultivated land, 15 parts of Radix Angelicae Sinensis, 17.5 parts of the root of kudzu vine, 7 parts of asarum, 4 parts of radix glycyrrhizae.
3. Chinese medicine composition according to claim 1, it is characterised in that also include the group of following parts by weight Into Radix Astragali 15-20 parts, Radix Codonopsis 15-20 parts.
4. according to the Chinese medicine composition described in claims 1 to 3 any one, it is characterised in that also including following The composition of parts by weight, Fructus Aurantii 10-15 parts, red sage root 10-15 parts, corydalis tuber 9-12 parts.
5. according to the Chinese medicine composition described in claims 1 to 3 any one, it is characterised in that also including following The composition of parts by weight, cassia twig 10-15 parts, Chinese ephedra 6-8 parts, rhizoma zingiberis 6-8 parts, earthworm 9-12 parts.
6. according to the Chinese medicine composition described in claims 1 to 3 any one, it is characterised in that also including following The composition of parts by weight, matrimony vine 10-15 parts, radix bupleuri 10-15 parts.
7. the Chinese medicine composition described in claim 1~6 any one is preparing the medicine of prevention and treatment osteoproliferation Application in thing.
CN201610312377.XA 2016-05-13 2016-05-13 A kind of Chinese medicine composition and its application in the medicine for preparing prevention and treatment osteoproliferation Pending CN107362227A (en)

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CN101411802A (en) * 2008-11-21 2009-04-22 赵献民 Black plaster for treating hyperosteogeny and preparation method thereof

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Application publication date: 20171121