CN104306644A - Disease prevention and control powdered traditional Chinese medicine composition for aquaculture and breeding of fine breed of Chinese soft shell turtle - Google Patents
Disease prevention and control powdered traditional Chinese medicine composition for aquaculture and breeding of fine breed of Chinese soft shell turtle Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
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- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/68—Plantaginaceae (Plantain Family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/708—Rheum (rhubarb)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
- A61K36/855—Clerodendrum, e.g. glorybower
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
Abstract
The invention provides a disease prevention and control powdered traditional Chinese medicine composition for aquaculture and breeding of a fine breed of Chinese soft shell turtle. The disease prevention and control powdered traditional Chinese medicine composition comprises 50-80 parts of fructus forsythia, 50-80 parts of isatis root, 50-80 parts of ground beetle, 35-50 parts of paris polyphylla, 35-50 parts of plantain herb, 50-80 parts of folium isatidis, 50-80 parts of adder-wort, 18-30 parts of Coptis chinensis, 18-40 parts of Scutellaria baicalensis, 18-35 parts of golden cypress, 18-35 parts of Rheum officinale, 30-35 parts of Radix Stellariae, 30-35 parts of Portulaca oleracea, 30-50 parts of radix sophorae flavescentis, 5-15 parts of Circium japonicum and 5-15 parts of fructus cnidii. According to the formula, the traditional Chinese medicine composition has the functions of clearing away heat and toxins as well as removing stasis and eliminating swelling and is prepared from carefully selected traditional herbal medicines with a wide antibacterial spectrum and an antiviral effect; the medicinal components are carefully selected and reasonable matched to take the synergistic effect of all the components. After being taken by Chinese soft shell turtles, the disease prevention and control powdered traditional Chinese medicine composition can alleviate various inflammations in intestinal tracts in the bodies of Chinese soft shell turtles, promote intestinal tract movement and remove physical signs such as damp and hot condition and damp toxin.
Description
Technical field
The present invention relates to the cultivation of reptile class, genetics and breeding technical field, be specifically related to one and cultivate for improved variety of China turtle, breed with the loose Chinese medicine composition of control.
Background technology
Wild Trionyx sinensis (Wiegmann) is commonly called as Trionyx sinensis Wiegmann, cuckold, foot fish, the soft-shelled turtle, has distribution throughout the country.Wild Trionyx sinensis (Wiegmann) can be used as medicine, and has nourishing YIN and clearing away heat, suppressing the hyperactive liver kidney tonifying, hard mass softening and resolving and the silt function that disappears.The demand of people to wild Trionyx sinensis (Wiegmann) is increasing for this reason.Due to the day by day rareness of recent wild Trionyx sinensis (Wiegmann), and it is higher to catch cost.Add that the wild Trionyx sinensis (Wiegmann) of existing medical evidence is substantially identical with the Trionyx sinensis (Wiegmann) nutritive value of artificial cultivation.People come into effect artificial cultivation Trionyx sinensis (Wiegmann).
In the process of artificial cultivation Trionyx sinensis (Wiegmann), in order to pursue economic benefit, raiser adopts high density greenhouse cultivation pattern mostly.Under high density greenhouse cultivation pattern, if when there is extensive infectious disease or concurrent inflammation, the Trionyx sinensis (Wiegmann) in culturing pool can mortality.Extreme loss is brought to raiser.For above-mentioned disease, raiser mainly adopts and in culturing pool, throws in a large amount of antibiotics medicament treat as bactericidal antiphlogistic medicine.This type of medicament easily produces drug residue in the health of Trionyx sinensis Wiegmann, affects eater healthy.
Summary of the invention
The invention provides one can bactericidal antiphlogistic, and integrate prevention, therapeutic efficiency for improved variety of China turtle cultivation, breed with the loose Chinese medicine composition of control.Solve in prior art, be used for treatment Trionyx sinensis (Wiegmann) when there is extensive infectious disease or concurrent inflammation, after using antibiotic medicament, in Trionyx sinensis (Wiegmann) body, produce drug residue, affect the problem that eater is healthy.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
A kind of be used for improved variety of China turtle cultivation, breed with the loose Chinese medicine composition of control, it is characterized in that described control is fallen apart and to make primarily of the proportioning raw materials of following weight portion: Fructus Forsythiae 50-80 parts, Radix Isatidis 50-80 parts, Eupolyphaga Seu Steleophaga 50-80 parts, Rhizoma Paridis 35-50 parts, Herba Plantaginis 35-50 parts, Folium Isatidis 50-80 parts, Rhizoma Bistortae 50-80 parts, Rhizoma Coptidis 18-30 parts, Radix Scutellariae 18-40 parts, Cortex Phellodendri 18-35 parts, Radix Et Rhizoma Rhei 18-35 parts, Radix Stellariae 30-35 parts, Herba Portulacae 30-35 parts, Radix Sophorae Flavescentis 30-50 parts, Radix Cirsii Japonici 5-15 part, Fructus Cnidii 5-15 part.
Above-mentioned for improved variety of China turtle cultivation, breed by the loose Chinese medicine composition method of control, the method comprises the following steps:
A. Fructus Forsythiae, Radix Isatidis, Eupolyphaga Seu Steleophaga, Rhizoma Paridis, Herba Plantaginis, Folium Isatidis, Rhizoma Bistortae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Stellariae, Herba Portulacae, Radix Sophorae Flavescentis, Radix Cirsii Japonici, Fructus Cnidii are pulverized respectively, cross 120 eye mesh screens and obtain drug powder;
B. the powder of Fructus Forsythiae, Radix Isatidis, Eupolyphaga Seu Steleophaga, Rhizoma Paridis, Herba Plantaginis, Folium Isatidis, Rhizoma Bistortae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Stellariae, Herba Portulacae, Radix Sophorae Flavescentis, Radix Cirsii Japonici, Fructus Cnidii puts into baking oven inner drying respectively, bake out temperature 80 DEG C, dry 30 minutes;
C. dried Rhizoma Bistortae powder, Rhizoma Coptidis powder, Radix Scutellariae powder, Radix Stellariae powder, Radix Sophorae Flavescentis powder are poured in mixer respectively by described proportioning, fully namely obtain the present composition after mixing.
In instant component: Herba Portulacae has heat-clearing and toxic substances removing, diuretic dries, loose blood detumescence, dust-collection sterilization, and anti-inflammatory analgetic, hemostasis removing heat from blood, cures mainly dysentery, enteritis, the diseases such as nephritis.Various places, Herba Portulacae China north and south are all produced, with all herbal medicine of plant, on the books in the medicine ancient books and records such as Compendium of Material Medica, " Kaibao Bencao ".
Radix Cirsii Japonici has heat-clearing and toxic substances removing, antiinflammatory, stops blooding and recovers the effect of liver function, promotion liver cell regeneration, being applicable to acute calenture struvite hemorrhage, yellow cellulitis, hepatitis, pyretic stranguria, hematuria etc.
Fructus Cnidii has warming the kidney to invigorate YANG; Removing dampness and killing parasites; The effects such as dispelling wind for relieving itching.Osthole, bergapton and the Trichophyton mentagrophytes of isopimpinellin in vitro tests to Trichophyton have strong activity; Xanthotoxol has significant Antifungal activities.
Folium Isatidis has resisting pathogenic microbes effect.Experiment in vitro shows: Folium Isatidis has broad ectrum antibiotic effect. and its decoct all has inhibitory action to a certain degree to staphylococcus aureus, alpha streptococcus, meningococcus, Diplococcus pneumoniae, micrococcus catarrhalis, Bacillus typhi, escherichia coli, hemophilus influenza, diphtheria corynebacterium and dysentery bacterium. and roadside Folium Isatidis decoct all has bactericidal action to multiple dysentery bacterium in vitro.
Rhizoma Bistortae is called: Herba Salviae Chinensis, Rhizoma Paridis, cold nature heat-clearing and toxic substances removing, removing heat from blood, for disease treatments such as enteritis, dysentery, hepatitis, bleeding hemorrhoidss.The ground such as Rhizoma Bistortae main product North China, northwest and Shandong, Jiangsu, Hubei, on the books in medicine ancient books and records such as " Bencao Tujings ".
Rhizoma Paridis antiviral, educates for popular rib adenitis, tonsillitis, swelling throat, otitis media, epidemic encephalitis type B, cruchet's disease etc.
Herba Plantaginis clearing away heat and promoting diuresis; Eliminating dampness by diuresis antidiarrheal.
The effects such as Rhizoma Coptidis has heat clearing and damp drying, eliminating fire and detoxication, for damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, the disease treatments such as unconsciousness due to high fever.The ground such as Rhizoma Coptidis main product Sichuan, Hubei, on the books in the medicine ancient books and records such as Shennong's Herbal.
Radix Scutellariae another name Radix Scutellariae, tsuchikane tea root, have heat clearing and damp drying, eliminating fire and detoxication, the effects such as hemostasis, for hygropyrexia, damp and hot feeling of fullness, and dysentery, jaundice, high hot excessive thirst, the diseases such as heat in blood tells nosebleed, carbuncle sore tumefacting virus.Radix Scutellariae originates in the ground such as Hebei, Liaoning, Shaanxi, Shanxi, on the books in medicine ancient books and records such as " Chinese Pharmacopoeias ".
Radix Et Rhizoma Rhei has attacks the effects such as stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances.
Cortex Phellodendri has heat clearing and damp drying, and pathogenic fire purging removes steams, effect of detoxification sore treatment.
Radix Stellariae is used as medicine with root, has the effects such as clearing away heat and cooling blood, cures mainly asthenia hectic fever due to YIN-deficiency, the diseases such as deficiency of YIN chronic malaria.Radix Stellariae main product is in the ground such as the northwestward, the Inner Mongol.
Radix Sophorae Flavescentis cures mainly the diseases such as damp-heat dysentery, discharging fresh blood stool, jaundice, edema, scabies, skin pruritus, noxious dampness skin infection.
Fructus Forsythiae, attribute: bitter, is slightly cold.Return lung, the heart, gallbladder meridian.Fructus Forsythiae has broad-spectrum antibacterial action, has very strong inhibitory action to staphylococcus aureus, Hayes dysentery bacterium, has certain inhibitory action to other pathogenic bacterium, influenza virus, fungus.There is antiinflammatory action.
Effect of Radix Isatidis is heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving, is mainly used in treating fever caused by exogenous pathogens, and epidemic febrile disease is from the beginning of, laryngopharynx swelling and pain, and maculae caused by violent heat pathogen, mumps, erysipelas, the excessive noxious heat cards such as carbuncle sore tumefacting virus, can combine the merit that heat-clearing and toxic substances removing played altogether by the medicine such as Folium Isatidis, Indigo Naturalis.
Eupolyphaga Seu Steleophaga is the effect with removing blood stasis, reunion of fractured tendons and bones, and has thrombolytic mechanism.Folium Isatidis effect is wind and heat dispersing, removing toxic substances and promoting subsidence of swelling, removing heat from blood function of gallbladder promoting.Be usually used in the treatment of the viral symptoms such as parotitis.Radix Cirsii Japonici sweet in the mouth, cool, nontoxic.Control haematemesis, epistaxis, hematuria, stranguria with blood, metrorrhagia, the diseases such as furuncle.Fructus Cnidii the kidney warming, dispel the wind, dampness, parasite killing.
Chinese medicine formula heat-clearing and toxic substances removing of the present invention, mass dissipating and swelling eliminating, the selected Chinese herbal medicine possessing has a broad antifungal spectrum and antivirus action.By selected drug component, reasonable compatibility, plays the synergism of each component.After using the present invention, the various inflammation of intestinal in Trionyx sinensis Wiegmann body can be alleviated, promote intestinal peristalsis promoting, eliminate the signs such as it is damp and hot, noxious dampness.Test shows: after this product twenty four hours, all have obvious inhibitory action to bacillus, vibrio, coccus and various virus, impels the increase of Trionyx sinensis Wiegmann appetite, vigor enhancing.The present invention significantly can strengthen again the immunologic function of Trionyx sinensis (Wiegmann) by enhancing body antibody titer, decreases the use of medicine, reduces sick chance, decrease water pollution and drug contamination.
detailed description of the invention:
Embodiment 1. 1 kinds cultivates for improved variety of China turtle, breed the loose Chinese medicine composition of use control, and the proportioning raw materials primarily of following weight portion is made: Fructus Forsythiae 50 parts, Radix Isatidis 500 parts, Eupolyphaga Seu Steleophaga 50 parts, Rhizoma Paridis 35 parts, Herba Plantaginis 35 parts, Folium Isatidis 50 parts, Rhizoma Bistortae 500 parts, Rhizoma Coptidis 18 parts, Radix Scutellariae 18 parts, Cortex Phellodendri 18 parts, Radix Et Rhizoma Rhei 18-part, Radix Stellariae 30 parts, Herba Portulacae 30 parts, Radix Sophorae Flavescentis 30 parts, Radix Cirsii Japonici 5 parts, Fructus Cnidii 5 parts.
Embodiment 2. 1 kinds cultivates for improved variety of China turtle, breed the loose Chinese medicine composition of use control, and the proportioning raw materials primarily of following weight portion is made: Fructus Forsythiae 80 parts, Radix Isatidis 80 parts, Eupolyphaga Seu Steleophaga 80 parts, Rhizoma Paridis 50 parts, Herba Plantaginis 50 parts, Folium Isatidis 80 parts, Rhizoma Bistortae 80 parts, Rhizoma Coptidis 30 parts, Radix Scutellariae 40 parts, Cortex Phellodendri 35 parts, Radix Et Rhizoma Rhei 35 parts, Radix Stellariae 35 parts, Herba Portulacae 35 parts, Radix Sophorae Flavescentis 50 parts, Radix Cirsii Japonici 15 parts, Fructus Cnidii 5 parts.
Embodiment 3. 1 kinds cultivates for improved variety of China turtle, breed the loose Chinese medicine composition of use control, and the proportioning raw materials primarily of following weight portion is made: Fructus Forsythiae 50 parts, Radix Isatidis 50 parts, Eupolyphaga Seu Steleophaga 80 parts, Rhizoma Paridis 35 parts, Herba Plantaginis 50 parts, Folium Isatidis 50 parts, Rhizoma Bistortae 80 parts, Rhizoma Coptidis 18 parts, Radix Scutellariae 18 parts, Cortex Phellodendri 35 parts, Radix Et Rhizoma Rhei 18 parts, Radix Stellariae 35 parts, Herba Portulacae 30 parts, Radix Sophorae Flavescentis 50 parts, Radix Cirsii Japonici 5 parts, Fructus Cnidii 5 parts.
Embodiment 4. 1 kinds cultivates for improved variety of China turtle, breed the loose Chinese medicine composition of use control, and the proportioning raw materials primarily of following weight portion is made: Fructus Forsythiae 80 parts, Radix Isatidis 80 parts, Eupolyphaga Seu Steleophaga 50 parts, Rhizoma Paridis 35 parts, Herba Plantaginis 50 parts, Folium Isatidis 80 parts, Rhizoma Bistortae 50 parts, Rhizoma Coptidis 30 parts, Radix Scutellariae 18 parts, Cortex Phellodendri 35 parts, Radix Et Rhizoma Rhei 18 parts, Radix Stellariae 35 parts, Herba Portulacae 30 parts, Radix Sophorae Flavescentis 50 parts, Radix Cirsii Japonici 5 parts, Fructus Cnidii 15 parts.
Embodiment 5. 1 kinds cultivates for improved variety of China turtle, breed the loose Chinese medicine composition of use control, and the proportioning raw materials primarily of following weight portion is made: Fructus Forsythiae 80 parts, Radix Isatidis 50, Eupolyphaga Seu Steleophaga 50 parts, Rhizoma Paridis 50 parts, Herba Plantaginis 35 parts, Folium Isatidis 50 parts, Rhizoma Bistortae 80 parts, Rhizoma Coptidis 18 parts, Radix Scutellariae 18 parts, Cortex Phellodendri 35 parts, Radix Et Rhizoma Rhei 18 parts, Radix Stellariae 35 parts, Herba Portulacae 30 parts, Radix Sophorae Flavescentis 30 parts, Radix Cirsii Japonici 15 parts, Fructus Cnidii 5 parts.
Embodiment 6. 1 kinds cultivates for improved variety of China turtle, breed the loose Chinese medicine composition of use control, and the proportioning raw materials primarily of following weight portion is made: Fructus Forsythiae 500 parts, Radix Isatidis 80 parts, Eupolyphaga Seu Steleophaga 50 parts, Rhizoma Paridis 50 parts, Herba Plantaginis 50 parts, Folium Isatidis 50 parts, Rhizoma Bistortae 50 parts, Rhizoma Coptidis 30 parts, Radix Scutellariae 18 parts, Cortex Phellodendri 18 parts, Radix Et Rhizoma Rhei 18 parts, Radix Stellariae 30, Herba Portulacae 30 parts, Radix Sophorae Flavescentis 50 parts, Radix Cirsii Japonici 5 parts, Fructus Cnidii 5 parts.
Embodiment 7. 1 kinds cultivates for improved variety of China turtle, breed the loose Chinese medicine composition of use control, and the proportioning raw materials primarily of following weight portion is made: Fructus Forsythiae 80 parts, Radix Isatidis 50 parts, Eupolyphaga Seu Steleophaga 50 parts, Rhizoma Paridis 35 parts, Herba Plantaginis 35 parts, Folium Isatidis 80 parts, Rhizoma Bistortae 50 parts, Rhizoma Coptidis 18 parts, Radix Scutellariae 18 parts, Cortex Phellodendri 18 parts, Radix Et Rhizoma Rhei 18 parts, Radix Stellariae 30 parts, Herba Portulacae 305 parts, Radix Sophorae Flavescentis 50 parts, Radix Cirsii Japonici 15 parts, Fructus Cnidii 5 parts.
More than prepare described in embodiment 1-7 for improved variety of China turtle cultivation, breed by the loose Chinese medicine composition method of control, adopt following steps to be prepared:
A. first with ultrafine crusher, respectively pulverization process is carried out to Fructus Forsythiae, Radix Isatidis, Eupolyphaga Seu Steleophaga, Rhizoma Paridis, Herba Plantaginis, Folium Isatidis, Rhizoma Bistortae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Stellariae, Herba Portulacae, Radix Sophorae Flavescentis, Radix Cirsii Japonici, Fructus Cnidii, and each drug powder obtained is separated placement;
B. get the special screens of 120 order specification sizes, impurity residual in respective medicated powder in step a sifts out, and obtains operable drug powder; Again the often kind of part medicated powder powder screened is put in baking oven respectively, bake out temperature is selected at 80 DEG C, take out from baking oven after dry 30 minutes;
C. last dried separately medicated powder powder is re-started proportioning by the drug component formula number in each embodiment, form medicinal powder mixture, finally the medicinal powder mixture prepared is poured in mixer in the lump, both obtained cultivating for improved variety of China turtle, breeding with the loose Chinese medicine composition of control after fully mixing.
Beneficial effect of the present invention is verified further below by way of curative effect of medication contrast test.
Select to suffer from that infectiousness is extremely strong, complication is many, A, B of frank Trionyx sinensis (Wiegmann) enteritis disease two mouthfuls of Trionyx sinensis (Wiegmann) culturing pools, A pool area is 3 mu, sick Trionyx sinensis Wiegmann quantity is 400; B pond is 3.5 mu, and sick Trionyx sinensis Wiegmann quantity is 600.
A pond is test tank, and the embodiment of the present invention 1 is made pharmaceutical composition, and this pharmaceutical composition and feedstuff fully mixed in the ratio of feedstuff gross weight 13%, every day throws something and feeds at twice, and each feeding volume can make disease Trionyx sinensis Wiegmann eat up in one hour to be advisable, to throw something and feed continuously 5 ~ 6 days.
B pond is contrast pond, and add garlicin in the ratio of feedstuff gross weight 13%, make bait feeding, throw something and feed at twice every day, each feeding volume can make disease Trionyx sinensis Wiegmann eat up in one hour to be advisable, to throw something and feed continuously 5 ~ 6 days.Its therapeutic outcome is as shown in table 1:
Table 1: culturing pool dispensing result of the test.
Conclusion (of pressure testing): after test tank application the present invention, sick Trionyx sinensis Wiegmann enteritis disease symptom improves, and mortality rate is effectively controlled, and mortality rate is only 1%.Though the sick fish symptom in contrast pond makes moderate progress, mortality rate is higher, up to 7%.Subsequently, the observation carried out A, B pond one month by a definite date shows: the Trionyx sinensis Wiegmann group in A culturing pool is grown fine, and recurs enteritis disease never again.Although the Trionyx sinensis Wiegmann mortality rate in the pool cultivated pond of B declines to some extent, still easily infect enteritis disease.
Claims (2)
1. the control that an improved variety of China turtle is bred is fallen apart, and it is characterized in that described control is fallen apart and to make primarily of the proportioning raw materials of following weight portion: Fructus Forsythiae 50-80 parts, Radix Isatidis 50-80 parts, Eupolyphaga Seu Steleophaga 50-80 parts, Rhizoma Paridis 35-50 parts, Herba Plantaginis 35-50 parts, Folium Isatidis 50-80 parts, Rhizoma Bistortae 50-80 parts, Rhizoma Coptidis 18-30 parts, Radix Scutellariae 18-40 parts, Cortex Phellodendri 18-35 parts, Radix Et Rhizoma Rhei 18-35 parts, Radix Stellariae 30-35 parts, Herba Portulacae 30-35 parts, Radix Sophorae Flavescentis 30-50 parts, Radix Cirsii Japonici 5-15 part, Fructus Cnidii 5-15 part.
2. the preparation method that the control that improved variety of China turtle is bred is fallen apart, is characterized in that described preparation method comprises the following steps:
A. Fructus Forsythiae, Radix Isatidis, Eupolyphaga Seu Steleophaga, Rhizoma Paridis, Herba Plantaginis, Folium Isatidis, Rhizoma Bistortae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Stellariae, Herba Portulacae, Radix Sophorae Flavescentis, Radix Cirsii Japonici, Fructus Cnidii are pulverized respectively, cross 120 eye mesh screens and obtain drug powder;
B. the powder of Fructus Forsythiae, Radix Isatidis, Eupolyphaga Seu Steleophaga, Rhizoma Paridis, Herba Plantaginis, Folium Isatidis, Rhizoma Bistortae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Stellariae, Herba Portulacae, Radix Sophorae Flavescentis, Radix Cirsii Japonici, Fructus Cnidii puts into baking oven inner drying respectively, bake out temperature 80 DEG C, dry 30 minutes;
C. dried Rhizoma Bistortae powder, Rhizoma Coptidis powder, Radix Scutellariae powder, Radix Stellariae powder, Radix Sophorae Flavescentis powder are poured in mixer respectively by described proportioning, fully namely obtain the present composition after mixing.
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