CN104306166B - A kind of salicylic acid microcapsules and preparation method thereof and skin care cream - Google Patents
A kind of salicylic acid microcapsules and preparation method thereof and skin care cream Download PDFInfo
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- CN104306166B CN104306166B CN201410563809.5A CN201410563809A CN104306166B CN 104306166 B CN104306166 B CN 104306166B CN 201410563809 A CN201410563809 A CN 201410563809A CN 104306166 B CN104306166 B CN 104306166B
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- salicylic acid
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Abstract
The invention discloses a kind of salicylic acid microcapsules and preparation method thereof and skin care cream.Salicylic acid microcapsules, are made up of core and wall material, and its mass ratio is 10:1~5:2.The skin care cream can effectively play salicylic acid exfoliating, while oil-control bacteriostatic skin-care acts on, reduce salicylic acid to skin strong impulse, reach salicylic slow release effect and improve salicylic acid security and stability.
Description
Technical field
The invention belongs to cosmetic field, specifically, is related to a kind of salicylic acid microcapsules and preparation method thereof and skin care
Cream.
Background technology
Salicylic acid is beta-hydroxy acid (Beta Hydroxy Acid), also known as BHA, B skin softening tartaric acid, is present in nature
In willow bark, Gaultheria leaf and sweet birch tree.Salicylic acid has the excess oil of dissolving facial pores and old dead and impaired angle
Cell plastid, suppress the effect of sebum secretion and bacteria breed, can also desalinate pigmented spots, reduce pore, remove fine wrinkles and
Improve aging and other effects caused by Exposure to Sunlight.But salicylic acid is insoluble in water and had compared with strong and stimulating, thus its application is by very
Big limitation.And the salicylic acid of microcapsules technology parcel is used, the original excitant of salicylic acid can be reduced, it is being played effect
Meanwhile act on milder.
The content of the invention
It can effectively suppress to cause what acne occurred it is an object of the invention to overcome the deficiencies of the prior art and provide a kind of
While three kinds of bacterium produce, salicylic acid microcapsules and its skin care cream of the salicylic acid to skin intense stimulus are reduced.
To achieve these goals, present invention employs following technical scheme：
A kind of salicylic acid microcapsules, are made up of wall material and core, and its mass ratio is 10:1~5:2.
In above-mentioned salicylic acid microcapsules, the mass ratio of the wall material and core is preferably 5:1.
In above-mentioned salicylic acid microcapsules, the core is salicylic acid；The wall material is made up of the component of following parts by weight：
Starch Sodium Octenyl Succinate 30-60 parts, beta cyclodextrin 30-60 parts, maltodextrin 5-40 parts.
In above-mentioned salicylic acid microcapsules, the wall material is preferably made up of the component of following parts by weight：Ocentyl succinic
Sodium starch 40-45 parts, beta cyclodextrin 40-45 parts, maltodextrin 15-20 parts.
The preparation method of above-mentioned salicylic acid microcapsules, comprises the following steps：Wall material and core are mixed, stirred,
Matter, formed by spray drying.
A kind of skin care cream, it is made up of salicylic acid microcapsules and auxiliary material, the weight hundred of salicylic acid microcapsules and matrix auxiliary material
Fraction is respectively 1-8%, 92-99%.Changed according to cream matrix adjunct ingredient, and salicylic acid microcapsules addition is not
Together, skin care cream includes：Scrub, acne eliminating cream, massage cream, Whelk-eliminating paste etc..
Compared with prior art, the present invention has the advantages that：Salicylic acid microcapsules prepared by the present invention, it can reduce
The original excitant of salicylic acid, make it while effect is played, act on milder.The skin care cream of the present invention can effectively press down
While three kinds of bacterium that system causes acne to occur produce, salicylic acid is reduced to skin strong impulse, reaches salicylic sustained release
Effect and raising bigcatkin willow absolute acid stability.
Embodiment
Below by way of specific embodiment come the present invention is further illustrated, but these embodiments simply to illustrate that,
It is not limitation of the present invention.
The scrub of embodiment 1
Taking salicylic acid 40g and wall material 100g, (wall material is by starch Sodium Octenyl Succinate 60g, beta cyclodextrin 30g and malt paste
Smart 10g compositions).Salicylic acid and wall material are mixed, stirred, homogeneous, salicylic acid microcapsules are obtained by spray drying.
Stearic acid 14.0；Lanolin 4.0；Mineral oil 28.0；Aluminosilicate magnesium 5.0；Triethanolamine 3.0；Glycerine 5.0；Bigcatkin willow
Sour microcapsules 2.0；Essence preservative 2.0；Water surplus；Scrub is made.(each material % by weight, summation 100%).
The acne eliminating cream of embodiment 2
Taking salicylic acid 30g and wall material 100g, (wall material is by starch Sodium Octenyl Succinate 50g, beta cyclodextrin 35g and malt paste
Smart 15g compositions).Salicylic acid and wall material are mixed, stirred, homogeneous, salicylic acid microcapsules are obtained by spray drying.
Crodaret 3.0；Stearic acid monoglycerides 3.0；Olive oil 1.0；Methyl p-hydroxybenzoate 0.2；
Stearic acid 3.0；Myristic acid 3.0；Salicylic acid microcapsules 4.0；Essence 2.0；Water surplus；Acne eliminating cream is made, and (each material is by weight
Measure %, summation 100%).
The massage cream of embodiment 3
Taking salicylic acid 20g and wall material 100g, (wall material is by starch Sodium Octenyl Succinate 40g, beta cyclodextrin 40g and malt paste
Smart 20g compositions).Salicylic acid and wall material are mixed, stirred, homogeneous, salicylic acid microcapsules are obtained by spray drying.
Lanolin 3.0；Saualane 8.0；Stearic acid goes alone ester 2.0；Hexadeca-octadecyl alcohol ether 1.0；Stearic acid 2.5；Hydroxyl is hard
Resin acid monooctyl ester；Hexadeca-octadecyl alcohol 2.0；Glycerine 3.0；Card ripple 9400.24；Triethanolamine (regulation pH to 6.5~7.0)；Salicylic acid
Microcapsules 6.0；Water surplus；Massage cream (each material % by weight, summation 100%) is made.
The Whelk-eliminating paste of embodiment 4
Taking salicylic acid 10g and wall material 100g, (wall material is by starch Sodium Octenyl Succinate 30g, beta cyclodextrin 55g and malt paste
Smart 15g compositions).Salicylic acid and wall material are mixed, stirred, homogeneous, salicylic acid microcapsules are obtained by spray drying.
Stearic acid 4.0；White Mineral Oil 5.0；Stearic acid goes alone ester 1.0；Glycerine monohydroxy stearate 2.0；Hexadeca-octadecyl alcohol
3.0；Hexadecanol caprylate 10.0；Glycerine 3.0；2% card ripple 94110.0；Triethanolamine 1.5；Salicylic acid microcapsules 8.0；Essence
Preservative 2.0；Water surplus；Whelk-eliminating paste (each material % by weight, summation 100%) is made.
The skin care cream bacteriostatic experiment of embodiment 5
Salicylic acid microcapsules acne eliminating cream will be contained and be used for staphylococcus aureus, MRSE and propionibacterium acnes three
The bacteriostatic experiment of kind germ, experimental result are shown in Table 1.
The bacteriostatic test of salicylic acid, salicylic acid microcapsules and the cream of microcapsules containing salicylic acid the results are shown in Table 1.Can from table
Know, salicylic acid has biocidal property in itself, and salicylic acid microcapsules are added in creams still has biocidal property to three kinds of bacteriums.
Inhibition zone result of the salicylic acid microcapsules acne eliminating cream of table 1. to 3 kinds of acne pathogenic bacteria
Note："-" represents insensitive, antibacterial circle diameter ＜ 7mm；"+" represents sensitive, 7~10mm of antibacterial circle diameter；" ++ " table
Show sensitivity, 10~15mm. of antibacterial circle diameter.
Claims (3)
1. a kind of salicylic acid microcapsules, are made up of wall material and core；The core is salicylic acid；The wall material is by following parts by weight
Component composition：Starch Sodium Octenyl Succinate 30-60 parts, beta cyclodextrin 30-60 parts, maltodextrin 5-40 parts；The wall material and
The mass ratio of core is 5:1；Preparation method comprises the following steps：Wall material and core are mixed, stirred, homogeneous, by spray
Mist is dried and formed.
2. salicylic acid microcapsules as claimed in claim 1, it is characterised in that the wall material by following parts by weight component group
Into：Starch Sodium Octenyl Succinate 40-45 parts, beta cyclodextrin 40-45 parts, maltodextrin 15-20 parts.
3. a kind of skin care cream, it is characterised in that be made up of the salicylic acid microcapsules described in claim 1 and matrix auxiliary material, bigcatkin willow
The percetage by weight of sour microcapsules and auxiliary material is respectively 1-8%, 92-99%.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410563809.5A CN104306166B (en) | 2014-10-21 | 2014-10-21 | A kind of salicylic acid microcapsules and preparation method thereof and skin care cream |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201410563809.5A CN104306166B (en) | 2014-10-21 | 2014-10-21 | A kind of salicylic acid microcapsules and preparation method thereof and skin care cream |
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| CN104306166A CN104306166A (en) | 2015-01-28 |
| CN104306166B true CN104306166B (en) | 2018-01-26 |
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Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106913471A (en) * | 2017-03-10 | 2017-07-04 | 佛山市禅香新材料有限公司 | A kind of salicylic acid solid microcapsules and preparation method thereof |
| CN107595655A (en) * | 2017-10-10 | 2018-01-19 | 上海格兰化妆品有限公司 | A kind of salicylic drug-loading system and its preparation method and application |
| CN108210346B (en) * | 2018-01-10 | 2020-06-23 | 上海应用技术大学 | Composite wall material microcapsule loaded with salicylic acid and preparation method thereof |
| CN108652009A (en) * | 2018-05-18 | 2018-10-16 | 南昌大学 | A kind of preparation method of sustained release digestion fish oil micro-capsule |
| CN109054000B (en) * | 2018-07-24 | 2021-08-06 | 中山大学 | Nano drug-loading system based on polysalicylic acid and preparation method and application thereof |
| CN108852913A (en) * | 2018-09-27 | 2018-11-23 | 上海应用技术大学 | A kind of facial cleanser and preparation method thereof comprising salicylic acid microcapsules |
| CN111150674A (en) * | 2020-03-02 | 2020-05-15 | 上海新高姿化妆品有限公司 | Acne removing composition with mild oil control function and preparation method thereof |
| CN113101375A (en) * | 2021-05-08 | 2021-07-13 | 惠州市绿亚生物材料有限公司 | Chitosan grafted salicylic acid microcapsule and preparation method thereof |
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| CN103263476A (en) * | 2013-05-30 | 2013-08-28 | 广州市绿乔生物科技有限公司 | Composite bacteriostatic agent for reducing irritation |
| CN103340805A (en) * | 2013-07-26 | 2013-10-09 | 付永旭 | Tea tree acne-cleaning and poison-drawing cream and preparation method thereof |
| CN103356440A (en) * | 2013-07-26 | 2013-10-23 | 付永旭 | Centella acne-cleaning speckle-removing gel and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103263476A (en) * | 2013-05-30 | 2013-08-28 | 广州市绿乔生物科技有限公司 | Composite bacteriostatic agent for reducing irritation |
| CN103340805A (en) * | 2013-07-26 | 2013-10-09 | 付永旭 | Tea tree acne-cleaning and poison-drawing cream and preparation method thereof |
| CN103356440A (en) * | 2013-07-26 | 2013-10-23 | 付永旭 | Centella acne-cleaning speckle-removing gel and preparation method thereof |
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| Title |
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| CN104306166A (en) | 2015-01-28 |
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