CN1286447C - Skin care combination containing liposome of compound fat - Google Patents
Skin care combination containing liposome of compound fat Download PDFInfo
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- CN1286447C CN1286447C CN 200410094009 CN200410094009A CN1286447C CN 1286447 C CN1286447 C CN 1286447C CN 200410094009 CN200410094009 CN 200410094009 CN 200410094009 A CN200410094009 A CN 200410094009A CN 1286447 C CN1286447 C CN 1286447C
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Abstract
The present invention discloses a skin-care compound containing mixed fat liposome, which is composed of 5 to 40 wt% of the mixed grease liposome and 60 to 95 wt% of base material, wherein the mixed grease liposome is prepared from lecithin as wall material embedding mixed grease in the weight ratio of 1: 3 to 5; the mixed grease is mixed up by olive oil, grape seed oil and wheat germ oil in a weight ratio of 1.5 to 2.5: 1: 1.5 to 2.5. Because of the olive oil, the grape seed oil and the wheat germ oil contained in the skin-care compound, the present invention can prevent skin wrinkles, enhance moist-keeping effect, remove pimples and acne, flatten fine wrinkles, bring favorable skin-care effect and avoid using various cosmetics with easy use. The addition of the wheat germ oil can avoid oxidization and keep the activity of functional compositions. The embedded mixed grease forms the liposome which has the functions of resisting oxidation, increasing the moisture-keeping performance and slowly releasing the functional compositions.
Description
Technical field
The present invention relates to a kind of skin care compositions, particularly a kind of skin care compositions that contains liposome of compound fat.
Background technology
At present, mostly only contain the oils and fats of single type in the existing cosmetics, can only satisfy user's needs of skin protection in a certain respect, for example, need sun-proofly remove speckle the time, use the cosmetics that contain olive oil, need when crease-resistant, use the cosmetics that contain Semen Tritici aestivi germ oil etc.When the user has many-sided skin protection to need, need buy multiple cosmetics and use simultaneously, use very inconvenient.Simultaneously, the oils and fats in the cosmetics exists with the oils and fats state, and is very easily oxidized, makes oils and fats lose activity in the extremely short time, be absorbed into to keep the active time short behind the skin, and the shelf-life of cosmetics is also short.
Summary of the invention
The objective of the invention is to, provide a kind of easy to use, in skin, keep the active time long, and the skin care compositions that contains liposome of compound fat of long shelf-life.
The technical solution adopted for the present invention to solve the technical problems is:
A kind of skin care compositions that contains liposome of compound fat is characterized in that, is made up of the liposome of compound fat of 5-40% and the substrate of 60-95% by weight percentage; Described liposome of compound fat is for being that the wall material carries out lipid-encapsulated product to compound lard with lecithin; The weight ratio of described compound lard and lecithin is 1: 3-5; Described compound lard is to be 1.5-2.5 by weight by olive oil, Oleum Vitis viniferae, Semen Tritici aestivi germ oil: 1: the product of the mixed of 1.5-2.5.
Described substrate is that benchmark is by weight percentage by glyceryl monostearate 1-8%, C with the weight of compositions
16-18Alcohol 1-5%, polyacrylic resin 0.1-1%, aliphatic alcohol polyethenoxy (20) ether 0.5-3%, antiseptic is an amount of, essence is an amount of, balance of deionized water composition.
The skin care compositions that contains liposome of compound fat of the present invention has following advantage:
1. contain olive oil, Oleum Vitis viniferae, three kinds of oils and fatss of Semen Tritici aestivi germ oil in the skin care compositions of the present invention, wherein, olive oil contains the nutritional labeling of multiple needed by human body, and its fatty acid and multiple natural grease soluble vitamin are very favourable to nourishing skin.Directly use the olive oil skin protection can prevent wrinkle of skin and coarse, make skin recover natural elasticity, gloss and tender has special absorbability to ultraviolet, is to prevent that burning sun from tanning by the sun and the superior good merchantable brand of severe cold frost to skin damage.Olive oil is clearly oiliness after using, and is easy to absorb.Oleum Vitis viniferae also contains a large amount of unsaturated fatty acids, and penetration is strong, usefulness, especially delicacy and sensitive skin in the time of can doing facial massage and treatment, oiliness, skin sore acne skin contain abundant vitamin, mineral, the moistening effect of skin can be strengthened, soft skin can be moistened simultaneously.It is the famous Natural antioxidant that Semen Tritici aestivi germ oil contains a large amount of vitamin Es, can stablize quintessence oil, makes effect more lasting.The characteristic that has free radical resisting simultaneously, but delay skin aging; Moistness is strong, can desalinate microgroove, striae gravidarum, cicatrix, increases the skin wetting power, to drying, hydropenia, wear out, the wrinkle skin is extremely helpful.Can reduce the left vestige of long on the face comedo.Be fit to various skin matter, black speck, chronic eczema, eczema are had certain effect.Also have sun-proof function, it is sun-proof to can be used for health.Three kinds of oils and fatss are mixed,, dispel the skin sore acne preventing wrinkle of skin and the coarse moistening effect that strengthens skin simultaneously, desalination microgroove, striae gravidarum, cicatrix, skin effect is good, and avoids using multiple cosmetics, and is easy to use.
2. owing to olive oil, Oleum Vitis viniferae contain a large amount of unsaturated fatty acids, oxidized easily in the short time at the utmost point, generation is become sour, and loses activity.The adding of Semen Tritici aestivi germ oil can be prevented the generation of oxidation, keeps the activity of functional component.
3. the olive oil among the present invention, Oleum Vitis viniferae, Semen Tritici aestivi germ oil mix the back and are formed liposome by the lecithin embedding, have the antioxidative effect, and after skin absorbs, the active retention time is long, can prolong the action time of functional component on skin.And lecithin is similar to the lipid conformation in the skin, is easy to by skin absorbs, also has the effect that increases moisture retention and slow release functional component, reaches the purpose of beauty and skin care for a long time.
The specific embodiment
Skin care compositions of the present invention is that the liposome that is formed by the lecithin embedding after mixing with olive oil, Oleum Vitis viniferae, Semen Tritici aestivi germ oil is a functional component, needs according to the cosmetics of producing add cosmetic base commonly used according to a conventional method again, form as excipient commonly used, emulsifying agent, antiseptic, essence, antioxidant etc.
For example: when producing skin care item, be that benchmark is by glyceryl monostearate 1-8%, C with the total composition
16-18Alcohol 1-5%, polyacrylic resin 0.1-1%, aliphatic alcohol polyethenoxy (20) ether 0.5-3%, antiseptic is an amount of, essence is an amount of, balance of deionized water composition substrate.
The liposome of the compound lard among the present invention is the product that adopts embedding techniques the compound lard of olive oil, Oleum Vitis viniferae, Semen Tritici aestivi germ oil to be carried out embedding for the wall material with lecithin.Concrete preparation method is:
(1) use dissolve with ethanol lecithin, remove insoluble matter, it is standby to get supernatant;
(2) at first above-mentioned phospholipid alcoholic solution is being stirred and suitably under the heating condition, lecithin formation emulsion soluble in water.
(3) add the compound lard of olive oil, Oleum Vitis viniferae, Semen Tritici aestivi germ oil then, constant temperature is handled 15min in 50 ℃ of water-baths under the nitrogen protection condition.
(4) reuse ultrasonic Treatment 10-60min becomes transparent or semitransparently until emulsion, be cooled to room temperature, can obtain the liposome of the compound lard of olive oil, Oleum Vitis viniferae, Semen Tritici aestivi germ oil.
In order to improve embedding rate, the compound lard of olive oil, Oleum Vitis viniferae, Semen Tritici aestivi germ oil and the ratio of lecithin are 1: 3-5, most preferably 1: 4.
Below be that example is in conjunction with specific embodiments to the detailed description of the invention with protective skin cream and facial treatment milk.
Embodiment 1: the preparation of the liposome of the compound lard of olive oil, Oleum Vitis viniferae, Semen Tritici aestivi germ oil:
1. the preparation of liposome
(1) taking by weighing olive oil 150 gram, Oleum Vitis viniferae 100 grams, Semen Tritici aestivi germ oil 150 grams respectively puts into container to be stirred well to mix homogeneously standby.
(2) get 10 gram lecithin and put into beaker, add acetone 50ml, roll cleaning repeatedly with little spoon, remove impurity wherein, it is white or little yellow that the color of lecithin is shoaled, and generally needs cleaning 3 times.
(3) with 50ml ethanol above-mentioned lecithin is all dissolved, remove insoluble matter, it is standby to get supernatant.
(4) at first above-mentioned lecithin alcoholic solution is being stirred and suitably under the heating condition, lecithin is dissolved in the 200ml water is forming emulsion.
(5) add the compound lard 2.5g of olive oil, Oleum Vitis viniferae, Semen Tritici aestivi germ oil then, constant temperature is handled 15min in 50 ℃ of water-baths under the nitrogen protection condition.
(6) in the tank of ultrasonic washing unit, pour suitable quantity of water into; under the nitrogen protection condition; the beaker that fills above-mentioned mixed solution is put into water; the addition of water is not as the criterion so that beaker is floating; ultrasonication was taken out after 20 minutes; with ethanol evaporation, the liposome of compound lard that obtains olive oil, Oleum Vitis viniferae, Semen Tritici aestivi germ oil is standby.
Embodiment 2: the preparation of the liposome of the compound lard of olive oil, Oleum Vitis viniferae, Semen Tritici aestivi germ oil:
(1) taking by weighing olive oil 200 gram, Oleum Vitis viniferae 100 grams, Semen Tritici aestivi germ oil 200 grams respectively puts into container to be stirred well to mix homogeneously standby.
(2) get 7.5 gram lecithin and put into beaker, add acetone 40ml, roll cleaning repeatedly with little spoon, remove impurity wherein, it is white or little yellow that the color of lecithin is shoaled, and generally needs cleaning 3 times.
(3) with 40ml ethanol above-mentioned lecithin is all dissolved, remove insoluble matter, it is standby to get supernatant.
(4) at first above-mentioned lecithin alcoholic solution is being stirred and suitably under the heating condition, forming emulsion among the water-soluble 200ml of lecithin.
(5) add the compound lard 2.5g of olive oil, Oleum Vitis viniferae, Semen Tritici aestivi germ oil then, constant temperature is handled 15min in 50 ℃ of water-baths under the nitrogen protection condition.
(6) in the tank of ultrasonic washing unit, pour suitable quantity of water into; under the nitrogen protection condition; the beaker that fills above-mentioned mixed solution is put into water; the addition of water is not as the criterion so that beaker is floating; ultrasonication was taken out after 30 minutes; with ethanol evaporation, the liposome of compound lard that obtains olive oil, Oleum Vitis viniferae, Semen Tritici aestivi germ oil is standby.
Embodiment 3: the preparation of the liposome of the compound lard of olive oil, Oleum Vitis viniferae, Semen Tritici aestivi germ oil:
(1) taking by weighing olive oil 250 gram, Oleum Vitis viniferae 100 grams, Semen Tritici aestivi germ oil 250 grams respectively puts into container to be stirred well to mix homogeneously standby.
(2) get 12.5 gram lecithin and put into beaker, add acetone 60ml, roll cleaning repeatedly with little spoon, remove impurity wherein, it is white or little yellow that the color of lecithin is shoaled, and generally needs cleaning 3 times.
(3) with 60ml ethanol above-mentioned lecithin is all dissolved, remove insoluble matter, it is standby to get supernatant.
(4) at first above-mentioned lecithin alcoholic solution is being stirred and suitably under the heating condition, lecithin is dissolved in the 200ml water is forming emulsion.
(5) add the compound lard 2.5g of olive oil, Oleum Vitis viniferae, Semen Tritici aestivi germ oil then, constant temperature is handled 15min in 50 ℃ of water-baths under the nitrogen protection condition.
(6) in the tank of ultrasonic washing unit, pour suitable quantity of water into; under the nitrogen protection condition; the beaker that fills above-mentioned mixed solution is put into water; the addition of water is not as the criterion so that beaker is floating; ultrasonication was taken out after 60 minutes; with ethanol evaporation, the liposome of compound lard that obtains olive oil, Oleum Vitis viniferae, Semen Tritici aestivi germ oil is standby.
Embodiment 4: the preparation of protective skin cream, wherein polyacrylic resin adopts carbopol 934.
Take by weighing liposome 10 grams, 3 gram glyceryl monostearates, the 4 gram C of the compound lard of the above-mentioned olive oil that makes, Oleum Vitis viniferae, Semen Tritici aestivi germ oil
16-18Alcohol, 0.4 gram carbopol, 934,2 gram aliphatic alcohol polyethenoxy (20) ethers (being AEO-20), 0.27 gram essence, 0.03 gram antiseptic, 80.3 gram deionized waters are made protective skin cream according to a conventional method.
Embodiment 5: the preparation of protective skin cream, wherein polyacrylic resin adopts carbopol 934.
Take by weighing liposome 20 grams, 5 gram glyceryl monostearates, the 3 gram C of the compound lard of the above-mentioned olive oil that makes, Oleum Vitis viniferae, Semen Tritici aestivi germ oil
16-18Alcohol, 0.5 gram carbopol, 934,2 gram aliphatic alcohol polyethenoxy (20) ethers (being AEO-20), 0.5 gram essence, 0.1 gram antiseptic, 68.9 gram deionized waters.Make protective skin cream according to a conventional method.
Embodiment 6: the preparation of protective skin cream, wherein polyacrylic resin adopts carbopol 934.
Take by weighing liposome 40 grams, 8 gram glyceryl monostearates, the 5 gram C of the compound lard of the above-mentioned olive oil that makes, Oleum Vitis viniferae, Semen Tritici aestivi germ oil
16-18Alcohol, 1 gram carbopol, 934,3 gram aliphatic alcohol polyethenoxy (20) ethers (being AEO-20), 0.5 gram essence, 0.2 gram antiseptic, 42.3 gram deionized waters are made protective skin cream according to a conventional method.
Implement 7: the facial treatment milk preparation, wherein polyacrylic resin is selected carbopol 941 for use.
Take by weighing liposome 10 grams, 1 gram glyceryl monostearate, the 1 gram C of the compound lard of the above-mentioned olive oil that makes, Oleum Vitis viniferae, Semen Tritici aestivi germ oil
16-18Alcohol, 0.1 gram carbopol, 941,0.5 gram aliphatic alcohol polyethenoxy (20) ether (being AEO-20), 0.18 gram essence, 0.02 gram antiseptic, 87.2 gram deionized waters are made facial treatment milk according to a conventional method.
Implement 8: the facial treatment milk preparation, wherein polyacrylic resin is selected carbopol 941 for use.
Take by weighing liposome 20 grams, 3 gram glyceryl monostearates, the 3 gram C of the compound lard of the above-mentioned olive oil that makes, Oleum Vitis viniferae, Semen Tritici aestivi germ oil
16-18Alcohol, 0.4 gram carbopol, 941,1 gram aliphatic alcohol polyethenoxy (20) ether (being AEO-20), 0.22 gram essence, 0.08 gram antiseptic, 72.3 gram deionized waters are made facial treatment milk according to a conventional method.
Implement 9: the facial treatment milk preparation, wherein polyacrylic resin is selected carbopol 941 for use.
Take by weighing liposome 30 grams, 6 gram glyceryl monostearates, the 4 gram C of the compound lard of the above-mentioned olive oil that makes, Oleum Vitis viniferae, Semen Tritici aestivi germ oil
16-18Alcohol, 0.6 gram carbopol, 941,1.5 gram aliphatic alcohol polyethenoxy (20) ethers (being AEO-20), 0.8 gram essence, 0.2 gram antiseptic, 56.9 gram deionized waters.Make facial treatment milk according to a conventional method.
The result of use experiment:
Method: select 150 volunteers to participate in the free trial activity, be divided into three groups at random, 50 people are one group, investigate respectively do not add three kind of plant compound lards, directly add three kind of plant compound lards, mixture is carried out embedding become the Emulsion that adds behind the liposome and recover natural elasticity making skin, prevent wrinkle of skin and coarse, moist intensity, the improvement degree of several aspects such as desalination microgroove is carried out regular information feedback.
In the trial product that every group provides, except that three vegetable oil, all the other compositions are identical, and in two groups of trial products of direct adding three vegetable oil that provide and adding three vegetable oil liposomees, the content of its three vegetable oil also is identical.
Requiring each group all is to use sooner or later once every day, uses according to conventional method.
Result: after 50 days, use volunteer's skin of common Emulsion almost not have what improvement, use the volunteer's skin gloss and the colour of skin that directly add three vegetable oil Emulsions to have part to improve, the volunteer that use contains three vegetable oil liposome emulsions is not only improving significantly aspect the skin gloss and the colour of skin, and wrinkle of skin, pigment obtain desalination, and skin elasticity also strengthens to some extent.
Conclusion: it is remarkable to utilize the present invention to contain the Emulsion skin effect that three vegetable oil liposomees make, and makes us taking like a shot, and liposome of the present invention helps its application in skin care item and the popularization in cosmetics.
Although relate to a kind of skin care compositions that contains liposome of compound fat and carried out special description disclosed with reference to embodiment, embodiment described above is illustrative and not restrictive, under the situation that does not break away from the spirit and scope of the present invention, all variations and modification are all within the scope of the present invention.
Claims (2)
1. a skin care compositions that contains liposome of compound fat is characterized in that, is made up of the liposome of compound fat of 5-40% and the substrate of 60-95% by weight percentage; Described liposome of compound fat is for being that the wall material carries out liposome embedded product to compound lard with lecithin; The weight ratio of described compound lard and lecithin is 1: 3-5; Described compound lard is to be 1.5-2.5 by weight by olive oil, Oleum Vitis viniferae, Semen Tritici aestivi germ oil: 1: the product of the mixed of 1.5-2.5.
2. the skin care compositions that contains liposome of compound fat according to claim 1 is characterized in that, described substrate is that benchmark is by weight percentage by glyceryl monostearate 1-8%, C with the weight of compositions
16-18Alcohol 1-5%, polyacrylic resin 0.1-1%, aliphatic alcohol polyethenoxy (20) ether 0.5-3%, antiseptic is an amount of, essence is an amount of, balance of deionized water composition.
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| CN 200410094009 CN1286447C (en) | 2004-12-24 | 2004-12-24 | Skin care combination containing liposome of compound fat |
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| CN 200410094009 CN1286447C (en) | 2004-12-24 | 2004-12-24 | Skin care combination containing liposome of compound fat |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9792269B2 (en) | 2002-07-19 | 2017-10-17 | Open Invention Network, Llc | Registry driven interoperability and exchange of documents |
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| CN103054782B (en) * | 2013-01-28 | 2014-11-05 | 沈群华 | Skin cream with skin moistening and nourishing function and preparation method thereof |
| CN103536472A (en) * | 2013-10-17 | 2014-01-29 | 苏州威尔德工贸有限公司 | Grape seed skin-tendering oil and preparation process thereof |
| CN111773118A (en) * | 2020-08-06 | 2020-10-16 | 上海市天乐日化厂 | Novel honey powder cake and preparation method thereof |
| CN111870549B (en) * | 2020-08-06 | 2022-10-28 | 上海市天乐日化厂 | Eye shadow and preparation method thereof |
| CN112168753A (en) * | 2020-09-30 | 2021-01-05 | 云南贝泰妮生物科技集团股份有限公司 | Active particle with barrier repair effect and preparation process thereof |
| CN112516010A (en) * | 2020-12-02 | 2021-03-19 | 广州巴宝莉化妆品有限公司 | Perfume slow-release liposome, preparation method and application in washing and protecting products |
| CN113041191A (en) * | 2021-03-23 | 2021-06-29 | 上海极爱生物科技有限公司 | Coenzyme Q10 pre-inclusion compound and preparation method and application thereof |
| CN116391850B (en) * | 2023-03-14 | 2024-05-17 | 华南理工大学 | Yolk oil microemulsion with high antioxidant activity and preparation method and application thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9792269B2 (en) | 2002-07-19 | 2017-10-17 | Open Invention Network, Llc | Registry driven interoperability and exchange of documents |
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