CN103356440A - Centella acne-cleaning speckle-removing gel and preparation method thereof - Google Patents

Centella acne-cleaning speckle-removing gel and preparation method thereof Download PDF

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CN103356440A
CN103356440A CN2013103169943A CN201310316994A CN103356440A CN 103356440 A CN103356440 A CN 103356440A CN 2013103169943 A CN2013103169943 A CN 2013103169943A CN 201310316994 A CN201310316994 A CN 201310316994A CN 103356440 A CN103356440 A CN 103356440A
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component
acne
herba centellae
condensation
skin
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CN103356440B (en
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付永旭
赵月美
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Guangdong Qiaoqiao Biotechnology Co. Ltd.
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付永旭
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Abstract

A centella acne-cleaning speckle-removing gel and a preparation method thereof are disclosed. The components of the centella acne-cleaning speckle-removing gel comprises: an acne-removing component A, an acne-removing component B, a matrix component, a neutralizing component and an auxiliary agent. The preparation method comprises the following steps: adding the matrix component into an agitating pan, stirring and heating to dissolve at 75-95 DEG C; adding the acne-removing component A, keeping warm at 75-85 DEG C, dissolving completely, cooling by circulating water; when the temperature is 55-65 DEG C, adding the acne-removing component B, stirring to completely dissolve; when the temperature is 45-55 DEG C, adding the neutralizing component, stirring to form a gel; and when the temperature is 35-45 DEG C, stirring uniformly to obtain the centella acne-cleaning speckle-removing gel. In the key links of acne preventing, acne removing, speckle removing, skin nourishing and the like of acne skin, the gel of the invention helps to adjust metabolism of the skin, improve quality of the skin, eradicate acne growth environment, and perform comprehensive, safe and effective nursing on the acne skin.

Description

The clean pox of Herba Centellae is dispelled and is printed condensation and preparation method thereof
Technical field
The present invention relates to a kind of novel acne-eliminating cosmetic technical field, be specially the clean pox of the Herba Centellae seal condensation and preparation method thereof of dispelling.
Background technology
Acne is the common pilosebaceous chronic inflammatory disease dermatoses of a kind of adolescence, claims again " acne " or " comedo ".Mainly be apt to occur in the vigorous positions of seborrhea such as buccal, forehead, breast and back.Generally show as acne, pimple, pustule, tuberosity, cyst and cicatrix.Acne is general without uncomfortable, but affects attractive in appearancely, often can make patients ' psychological produce certain inferiority complex, if early time treatment is improper, even can form permanent cicatrix, brings be difficult to throughout one's life eliminate sorry to the patient.
The pathogenic factor more complicated of acne is the synergistic result of many factors, mainly comprises: androgen hypersecretion, sebum produce and increase, follicular epithelium hyperkeratosis, a large amount of increments of propionibacterium acnes etc.In addition, heredity is also participated with immune factor, and living habit (hygienic habit, sleep, diet, anxiety, fatigue, emotion, skin care item) also is relative to the generation of acne.
Generally speaking, anti-acne should be multi-faceted in addition maintenance conditioning, just can reach the effect of taking stopgap measures and effecting a permanent cure.The method of anti-acne is a lot, such as antibiotic for oral administration, with hormone regulating endocrine, dietetic regulation etc., also has a kind of relatively effective method to carry out exactly the anti-acne nursing.In order to remove the acne that has generated, available safely and effectively anti-acne skin care item carry out certain anti-acne nursing to skin.To accelerate the cutin metabolism, remove the top layer cutin, dredging fat secretion path also suppresses the sebum secretion of skin, and the incrustation of accelerates acne comes off, and presses down the propionibacterium acnes that extremely produces acne, fast antiinflammatory, the acne healing is accelerated in the prevention secondary infection; Repair the damaged tissues of skin epithelial layer, rear pigmentation and cicatrization reduce inflammation; Promote skin immunity, reduce the regeneration of skin allergy and acne.
Various for the anti-acne of acne seal product in the market, the seal weak effect that goes to dispel adopts the physics attrition mostly, and cost is high, has a big risk, and the patient suffering is large, DeGrain, and safety, still difficult prediction of sequela.Such as the fruit cosmetic improper use, can cause the major injury of skin.
Summary of the invention
The object of the present invention is to provide the clean pox of a kind of Herba Centellae seal condensation of dispelling
And preparation method thereof.The method adopts oils and fats quality regulation and control science and technology, utilize safety and the true effect property of the Chinese medicines such as Radix Ginseng to repair the characteristics science compatibilities such as property in conjunction with high activity, high osmosis, the height of the quintessence oils such as Herba Centellae, Radix Hamamelidis Mollis, print, support the key link adjusting skin metabolisms such as skin from anti-pox, anti-acne, the acne removing of acne-prone skin, improve the skin quality, eradicate the acne growing environment, make acne-prone skin obtain comprehensive, safe and effective nursing.
For achieving the above object, the invention provides following technical scheme:
The clean pox of the Herba Centellae seal condensation of dispelling comprises following weight portion composition: anti-acne component A:3.60-6.7 part, take 4.6-5.7 part as best; Anti-acne component B:3.04-6.10 part is take 4.04-5.10 part as best; The substrate component; In and component: 0.60-1.00 part; Auxiliary agent component: 0.10-0.15 part;
Described anti-acne component A comprises following weight portion composition:
Salicylic acid microcapsule 2.50-5.00 part
Modification allantoin 1.00-1.50 part
Bisabolol 0.10-0.20 part
Described anti-acne component B comprises following weight portion composition:
Described substrate component comprises following weight portion composition:
Figure BSA0000093045790000022
Figure BSA0000093045790000031
In described and component, comprise following weight portion composition:
Triethanolamine 0.60-1.00 part
Described auxiliary agent component composition is antiseptic.
The clean pox of the Herba Centellae seal condensation of dispelling
Manufacture method, may further comprise the steps:
(1) the substrate component is added agitated kettle, agitating heating is dissolved to 75-95 ℃, take 85 ℃ for best, add anti-acne component A, insulation is to 75-85 ℃, take 78-82 ℃ as the best, behind dissolve complete, the open cycle water cooling;
When (2) temperature drops to 55-65 ℃, take 58-62 ℃ as best, add anti-acne component B, be stirred to dissolve complete;
When (3) temperature drops to 45-55 ℃, take 48-52 ℃ as best, in the adding and component, be stirred to gel;
When (4) temperature drops to 35-45 ℃, take 38-42 ℃ as best, add the auxiliary agent component, stir, namely get the clean pox of the Herba Centellae seal condensation of dispelling
Beneficial effect
The present invention compares with product in the past, has the following advantages:
1, main component effect among the present invention: salicylic acid microcapsule, it is salicylic micro encapsulation product, it is perfect common bigcatkin willow solubility in acid is poor, be difficult to add, easily cause the problem such as skin stimulation, the good slow releasing function of performance in product, have outstanding exfoliation, unclogging ability, effectively dispel the aging horn cell of piling up in skin surface and the pore and causing pore to stop up, cleaning is also dispelled the unnecessary oils and fats of skin surface, reduces and prevent the generation of blackhead and hoary hair's acne.Azelaic acid can suppress and kill skin surface and intrafollicular antibacterial, eliminates pathogen, prevents the skin generation keratinization effect of acne infection, reduces pigmentation and reduces the melasma damage, softens the acne skin and dispels the pox seal; Anthocyanidin is a kind of strong antioxidant, and it can protect human body to avoid the damage of free radical, improves the smoothness of blood circulation and enhancement skin, inflammation-inhibiting and allergy; Retinol can accelerate cell regeneration and make cell rejuvenation, level and smooth refinement horny layer, stimulation collagen hypertrophy.Herba Centellae extract and Radix Ginseng extract can stimulate the deep skin cell to substitute, and can compact epidermis and corium coupling part limber up skin, help impaired organization healing and consolidation skin.The Radix Hamamelidis Mollis quintessence oil has heat-clearing and toxic substances removing, releives convergence, the effect that control is oily, antibiotic.Cooperate modification allantoin (antiallergic, the skin immunity that strengthens), bisabolol (antiinflammatory) to play synergistic function.
2, the clean pox of the Herba Centellae of the present invention seal condensation of dispelling
Main effect: rapid osmotic hair follicle depths, alleviate the senses of discomfort such as small pox redness, pain, make skin comfortable; Conditioning small pox skin water oil balance suppresses small pox regeneration; Decompose dermal melanin, make flaw and pox seal disappear fast.
3, product of the present invention is printed on for the pox that has generated and well dispels effect, uses once can obviously desalinating the pox seal week, uses continuously two all above pox seals to reduce and reaches more than 90%; Can prevent the generation of pox seal for newborn small pox.
The specific embodiment
Below in conjunction with the embodiment of the invention, the technical scheme in the embodiment of the invention is clearly and completely described, obviously, described embodiment only is the present invention's part embodiment, rather than whole embodiment.Based on the embodiment among the present invention, those of ordinary skills belong to the scope of protection of the invention not making the every other embodiment that obtains under the creative work prerequisite.
Embodiment 1
The clean pox of the Herba Centellae seal condensation of dispelling comprises following weight portion composition: anti-acne component A:3.60 part; Anti-acne component B:3.04 part; The substrate component; In and component: 0.60 part; Auxiliary agent component: 0.10 part;
Described anti-acne component A comprises following weight portion composition:
2.5 parts of salicylic acid microcapsules
1.00 parts of modification allantoin
0.10 part of bisabolol
Described anti-acne component B comprises following weight portion composition:
Figure BSA0000093045790000051
Described substrate component comprises following weight portion composition:
In described and component, comprise following weight portion composition:
0.60 part of triethanolamine
Described auxiliary agent component composition is antiseptic.
The clean pox of Herba Centellae is dispelled and is printed condensation and preparation method thereof, may further comprise the steps:
(1) the substrate component is added agitated kettle, agitating heating is dissolved to 75 ℃, adds anti-acne component A, be incubated to 75 ℃, and behind dissolve complete, the open cycle water cooling;
When (2) temperature drops to 55 ℃, add anti-acne component B, be stirred to dissolve complete;
When (3) temperature drops to 45 ℃, in the adding and component, be stirred to gel;
When (4) temperature drops to 35 ℃, add the auxiliary agent component, stir, namely get the clean pox of the Herba Centellae seal condensation of dispelling
Embodiment 2
The clean pox of the Herba Centellae seal condensation of dispelling
, comprise following weight portion composition: anti-acne component A:5.15 part; Anti-acne component B:4.57 part; The substrate component; In and component: 0.80 part; Auxiliary agent component: 0.13 part;
Described anti-acne component A comprises following weight portion composition:
3.75 parts of salicylic acid microcapsules
1.25 parts of modification allantoin
0.15 part of bisabolol
Described anti-acne component B comprises following weight portion composition:
Figure BSA0000093045790000061
Described substrate component comprises following weight portion composition:
Figure BSA0000093045790000062
In described and component, comprise following weight portion composition:
0.80 part of triethanolamine
Described auxiliary agent component composition is antiseptic.
The clean pox of the Herba Centellae seal condensation of dispelling
And preparation method thereof, may further comprise the steps:
(1) the substrate component is added agitated kettle, agitating heating is dissolved to 85 ℃, adds anti-acne component A, be incubated to 80 ℃, and behind dissolve complete, the open cycle water cooling;
When (2) temperature drops to 60 ℃, add anti-acne component B, be stirred to dissolve complete;
When (3) temperature drops to 50 ℃, in the adding and component, be stirred to gel;
When (4) temperature drops to 40 ℃, add the auxiliary agent component, stir, namely get the clean pox of the Herba Centellae seal condensation of dispelling.
Embodiment 3
The clean pox of the Herba Centellae seal condensation of dispelling comprises following weight portion composition: anti-acne component A:6.7 part; Anti-acne component B:6.10 part; The substrate component; In and component: 1.00 parts; Auxiliary agent component: 0.15 part;
Described anti-acne component A comprises following weight portion composition:
5.00 parts of salicylic acid microcapsules
1.50 parts of modification allantoin
0.20 part of bisabolol
Described anti-acne component B comprises following weight portion composition:
Figure BSA0000093045790000071
Described substrate component comprises following weight portion composition:
In described and component, comprise following weight portion composition:
1.00 parts of triethanolamine
Described auxiliary agent component composition is antiseptic.
The clean pox of Herba Centellae is dispelled and is printed condensation and preparation method thereof, may further comprise the steps:
(1) the substrate component is added agitated kettle, agitating heating is dissolved to 95 ℃, adds anti-acne component A, be incubated to 85 ℃, and behind dissolve complete, the open cycle water cooling;
When (2) temperature drops to 65 ℃, add anti-acne component B, be stirred to dissolve complete;
When (3) temperature drops to 55 ℃, in the adding and component, be stirred to gel;
When (4) temperature drops to 45 ℃, add the auxiliary agent component, stir, namely get the clean pox of the Herba Centellae seal condensation of dispelling
To those skilled in the art, obviously the invention is not restricted to the details of above-mentioned example embodiment, and in the situation that does not deviate from spirit of the present invention or basic feature, can realize the present invention with other concrete form.Therefore, no matter from which point, all should regard embodiment as exemplary, and be nonrestrictive, scope of the present invention is limited by claims rather than above-mentioned explanation, therefore is intended to include in the present invention dropping on the implication that is equal to important document of claim and all changes in the scope.
In addition, be to be understood that, although this description is described according to embodiment, but be not that each embodiment only comprises an independently technical scheme, this narrating mode of description only is for clarity sake, those skilled in the art should make description as a whole, and the technical scheme among each embodiment also can through appropriate combination, form other embodiments that it will be appreciated by those skilled in the art that.

Claims (7)

1. the clean pox of the Herba Centellae seal condensation of dispelling is characterized in that, comprises following weight portion composition: anti-acne component A:3.60-6.7 part; Anti-acne component B:3.04-6.10 part; The substrate component; In and component: 0.60-1.00 part; Auxiliary agent component: 0.10-0.15 part;
Described anti-acne component A comprises following weight portion composition:
Salicylic acid microcapsule 2.50-5.00 part
Modification allantoin 1.00-1.50 part
Bisabolol 0.10-0.20 part
Described anti-acne component B comprises following weight portion composition:
Figure FSA0000093045780000011
Described substrate component comprises following weight portion composition:
Figure FSA0000093045780000012
In described and component, comprise following weight portion composition:
Triethanolamine 0.60-1.00 part
Described auxiliary agent component composition is antiseptic.
2. the clean pox of the Herba Centellae according to claim 1 seal condensation of dispelling is characterized in that described anti-acne component A:4.6-5.7 part.
3. the clean pox of the Herba Centellae according to claim 1 seal condensation of dispelling is characterized in that described anti-acne component B:4.04-5.10 part.
4. the clean pox of Herba Centellae is dispelled and is printed the manufacture method of condensation, it is characterized in that, may further comprise the steps:
(1) the substrate component is added agitated kettle, agitating heating is dissolved to 75-95 ℃, adds anti-acne component A, and insulation is arrived 75-85 ℃, behind dissolve complete, and the open cycle water cooling;
When (2) temperature drops to 55-65 ℃, add anti-acne component B, be stirred to dissolve complete;
When (3) temperature drops to 45-55 ℃, in the adding and component, be stirred to gel;
When (4) temperature drops to 35-45 ℃, add the auxiliary agent component, stir, namely get the clean pox of the Herba Centellae seal condensation of dispelling
5. the clean pox of Herba Centellae according to claim 4 is dispelled and is printed condensation and preparation method thereof, it is characterized in that, when temperature drops to 60 ℃, adds anti-acne component B.
6. the clean pox of the Herba Centellae according to claim 4 seal condensation and preparation method thereof of dispelling is characterized in that, when temperature drops to 50 ℃, in the adding and component.
7. the clean pox of Herba Centellae according to claim 4 is dispelled and is printed condensation and preparation method thereof, it is characterized in that, when temperature drops to 40 ℃, adds the auxiliary agent component.
CN201310316994.3A 2013-07-26 2013-07-26 Centella acne-cleaning speckle-removing gel and preparation method thereof Active CN103356440B (en)

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Cited By (4)

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Publication number Priority date Publication date Assignee Title
CN104306166A (en) * 2014-10-21 2015-01-28 中山大学惠州研究院 Salicylic acid microcapsule, preparation method and skin-protecting cream thereof
CN105362480A (en) * 2014-08-12 2016-03-02 柯宏 External application traditional Chinese medicine composition for acne prevention and treatment
CN106580844A (en) * 2016-11-26 2017-04-26 无锡市汉方八珍科技有限公司 Lotion for repairing facial skin and preparation method thereof
CN110974711A (en) * 2019-12-11 2020-04-10 上海应用技术大学 Azelaic acid microcapsule and preparation method thereof

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105362480A (en) * 2014-08-12 2016-03-02 柯宏 External application traditional Chinese medicine composition for acne prevention and treatment
CN104306166A (en) * 2014-10-21 2015-01-28 中山大学惠州研究院 Salicylic acid microcapsule, preparation method and skin-protecting cream thereof
CN104306166B (en) * 2014-10-21 2018-01-26 中山大学惠州研究院 A kind of salicylic acid microcapsules and preparation method thereof and skin care cream
CN106580844A (en) * 2016-11-26 2017-04-26 无锡市汉方八珍科技有限公司 Lotion for repairing facial skin and preparation method thereof
CN110974711A (en) * 2019-12-11 2020-04-10 上海应用技术大学 Azelaic acid microcapsule and preparation method thereof

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Effective date of registration: 20170726

Address after: 510800 Guangdong city in Guangzhou Province, Xinhua Street, Huadu District, cloth Road No. 29

Patentee after: Guangdong Qiaoqiao Biotechnology Co. Ltd.

Address before: The black dragon town of Tanghe County in Henan province 473408 West Zhangzhuang Geng Camp No. 65 group

Patentee before: Fu Yongxu