CN104288642A - Traditional Chinese medicine composition for treating bacterial pneumonia as well as preparation method and application thereof - Google Patents

Traditional Chinese medicine composition for treating bacterial pneumonia as well as preparation method and application thereof Download PDF

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CN104288642A
CN104288642A CN201410556981.8A CN201410556981A CN104288642A CN 104288642 A CN104288642 A CN 104288642A CN 201410556981 A CN201410556981 A CN 201410556981A CN 104288642 A CN104288642 A CN 104288642A
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parts
herba
chinese medicine
bacterial pneumonia
medicine composition
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徐艳
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/10—Bryophyta
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/51—Gentianaceae (Gentian family)
    • A61K36/515—Gentiana
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9062—Alpinia, e.g. red ginger or galangal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

Abstract

The invention provides a traditional Chinese medicine composition for treating bacterial pneumonia. The traditional Chinese medicine is prepared from the following materials in parts by weight: 14 parts of rosary vine, 12 parts of root of ground cotoneaster, 15 parts of sophora davidii leaves, 16 parts of mentha crispate, 20 parts of rhizome alpiniae pumilae, 12 parts of Chinese anaphalis, 14 parts of herb of Kweiyang betony, 15 parts of mysore thorn root, 16 parts of sensitive joint vetch leaf, 10 parts of red rhodobryum, 12 parts of coriaceous knotweed rhizome, 14 parts of stylophorum lasiocarpum, 15 parts of maianthemum bifolium, 13 parts of sedum lineare thunb, 13 parts of radix gentianae, 8 parts of cryptotaenia japonica, 12 parts of geum aleppicum and 15 parts of melilotus officinalis. The traditional Chinese medicine composition can be used for treating bacterial pneumonia.

Description

A kind of Chinese medicine composition and preparation method and application treating bacterial pneumonia
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition and the preparation method and application that treat bacterial pneumonia.
Background technology
Bacterial pneumonia is modal pneumonia, is also one of modal infectious disease.It mainly comprises streptococcus pneumoniae, staphylococcus aureus, α-hemolytic streptococcus, klebsiella pneumoniae, hemophilus influenza, pseudomonas aeruginosa pneumonia etc.Very big to the health threat of child and old people.By anatomical classification, pneumonia can be divided into great Ye, lobular and chromic fibrous.For ease for the treatment of, now press etiological classification more, mainly contain infectious and physics and chemistry if lonizing radiation, poison, medicine and allergy are as hypersensitivity pneumonitis etc., the clinical findings overwhelming majority is the infectious pneumonia that antibacterial, virus, chlamydia, mycoplasma, rickettsia, fungus and parasite etc. cause, wherein common with antibacterial.The pathogen of pneumonia is because of age, accompanying diseases and immune functional state, acquisition pattern and have larger difference.The common causative of community acquired pneumonia is streptococcus pneumoniae, hemophilus influenza, staphylococcus aureus, micrococcus scarlatinae, legionella, anaerobe and virus, mycoplasma and chlamydia etc., in nosocomial pneumonia in patients then with bacillus pyocyaneus and other pseudomonass, pneumobacillus, escherichia coli, cloaca and generation enterobacteria, Bacillus proteus, Methicillin-resistant Staphylococcus aureus (MRSA) and fungus etc. common.Aspiration pneumonitis great majority are anaerobic infection.Lack effective medicine at present.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine composition and the preparation method and application that treat bacterial pneumonia.
Technical scheme: the object of the invention is by following scheme realize:
Treat a Chinese medicine composition for bacterial pneumonia, it is prepared by the raw material of following parts by weight: Herba Ceropegiae Christensenianae 14 parts, Radix Cotoneastri Perpusillae 12 parts, Folium Sophorae viciifoliae 15 parts, Mentha spicata L. 16 parts, Rhizoma alpiniae pumilae 20 parts, Herba Anaphalidis 12 parts, Herba stachydis kouyangensis 14 parts, Radix Caesalpiniae Radicis 15 parts, Folium Aeschynomenes indicae 16 parts, Rhodobryum roseum Limpr. 10 parts, Rhizoma Polygoni coriacei 12 parts, Herba Stylophori Lasiocapi 14 parts, Herba Maianthemi Bifolii 15 parts, Mus tooth half 13 parts, Radix haleniae ellipticae 13 parts, Caulis et folium cryptotaeniae japonicae 8 parts, geum aleppicum 12 parts, Herba Stenolomatis Chusani 15 parts.
The application of Chinese medicine composition in the medicine of preparation treatment bacterial pneumonia of described treatment bacterial pneumonia.
In the present invention, Herba Ceropegiae Christensenianae is asclepiadaceae Herba Ceropegiae Christensenianae Ceropegia christenseniana Hand.-Mazz., with all herbal medicine.Acid, flat.Heat-clearing and toxic substances removing.
Radix Cotoneastri Perpusillae is the root that rosaceous plant lobule puts down a Fructus Cotoneastri Acutifolii.The whole year can adopt.Cool in nature, sour-puckery flavor.Removing damp-heat.
Folium Sophorae viciifoliae is the leaf of leguminous plant Radix Sophorae Viciifoliae Sophora davidii (Franch.).Cure mainly epistaxis; Have blood in stool; Furuncle swelling toxin; Scabies; Scald; Trichomonas vaginitis.
Mentha spicata L., Latin is called Mentha spicata, perennial herb, and height about 1.3 meters, has branch.Rhizome spreads, and stem is square, in purple or bottle green.Dispelling wind, regulates the flow of vital energy, pain relieving.Cure cold, cough, headache, abdominal distention, dysmenorrhea.The present invention is with all herbal medicine.
Rhizoma alpiniae pumilae is Zingiberaceae Alpinia plants Huashan Rhizoma Zingiberis Recens Alpinia chinensis Rosc., is used as medicine with root stock.Summer excavates, and cleans and dries.Pungent, temperature.Expelling wind and removing dampness, vital energy regualting and blood circulation-promoting, removing toxic substances, pain relieving.Relieving cough and asthma, dispersing cold for relieving pain, except rheumatism, separates sore.For wind and cold cough with asthma, peratodynia, Fengshi Guanjie pain, falls and damages blood stasis stagnation, menoxenia, innominate toxic swelling.
Herba Anaphalidis is the herb of feverfew Herba Anaphalidis, antitussive, eliminate the phlegm, antiasthmatic effect, control anemofrigid cold, acute and chronic tracheitis, dysentery, enteritis.
Herba stachydis kouyangensis is herb or the root of the wild manna of labiate.Summer, autumn gather, and clean and dry.Eliminating inflammation and expelling toxin, draws out the pus.Control furuncle, osteomyelitis, mash deposited affected part with fresh grass.The present invention is with all herbal medicine.
Radix Caesalpiniae Radicis is root or the root bark of leguminous plant Semen Caesalpiniae.Latin name: Caesalpinia decapetala (Roth) Alston.Toil, temperature, dispels the wind, cold expelling, dehumidifying.Cure cold cough, general pain, lumbago, laryngalgia, toothache, traumatic injury, lymphogranuloma inguinale inguinal bubo.The present invention is used as medicine with root.
Folium Aeschynomenes indicae is the leaf of leguminous plant Herba Aeschynonenes Indicae, can treat carbuncle, the diseases such as wound hemorrhage.
Rhodobryum roseum Limpr., Latin is called Rhodobryum roseum (Hedw.) Limpr., pungent, bitter, flat.Tranquilizing by nourishing the heart, liver heat removing and eyesight improving.For severe palpitation, neurasthenia, conjunctival congestion and swelling pain is controlled in external.Perennial bryophyte; How scattered in flakes; Root state stem horizontal walk, have most hair shape rhizoid.Stem racemosus, uprightly, aubergine.Inferior leads is tiny, film quality, and flakey adhesion is in stem; Stem top is green, and comparatively grow up, multilevel cluster becomes rosette-stape, the blade shape of falling ovum lanceolar or long inverted ovoid, and serration is arranged at top, bottom Quan Yuan, and involute, middle rib reaches blade tip.Cluster in stem top clump several sporinite; Seta is elongated, upper end bow, and sporangium is sagging, reddish yellow, long oval cylindricality, and opercule is convex, has short beak.The present invention is with all herbal medicine.
Rhizoma Polygoni coriacei, Latin literary fame: Hemsleya sphaerocarpa Kuang et A.M.Lu belongs to Cucurbitaceae Genus Hemsleya, perennial root draft, Gao Keda 1 meter.Be distributed in a kind of herbaceous species plant on the ground such as Yunnan, Guizhou, under the broad-leaf forest limit being born in height above sea level 800-1400 rice or mountain valley sparse woods more.Heat clearing away, removing toxic substances, convergence, granulation promoting.Control dysentery, diarrhoea, carbuncle, hemorrhoid, burn.The present invention is with all herbal medicine.
Herba Stylophori Lasiocapi is Papaveraceae Stylophorum plant human blood grass Stylophorum lasiocarpum (Oliv.) Fedde, with all herbal medicine.Autumn gathers, and dries.Bitter, puckery, flat.Promoting blood flow to regulate menstruation, scattered silt pain relieving.For menoxenia, traumatic injury.
Herba Maianthemi Bifolii is the herb of liliaceous plant Herba Maianthemi Bifolii, cooling blood for hemostasis, heat-clearing and toxic substances removing, main haematemesis, hematuria, menorrhagia, traumatic hemorrhage, sore, carbuncle and painful swelling.Classification system is Maianthemum bifolium (L.) Fr.Schmidt.
Mus tooth half is the herb of Crassulaceae sengreen Herba Stellariae Alsines Sedum lineare Thunb..The four seasons can adopt, and clean, using fresh herb or dry.Heat-clearing and toxic substances removing, detumescence hemostasis.For pharyngolaryngitis, hepatitis, cancer of pancreas; Burn and scald is controlled in external, traumatic hemorrhage, herpes zoster, sore swollen toxin, venom.
Radix haleniae ellipticae is that Gentianaceae Herba Haleniae Corniculatae platymiscium purple spends anchor Halenia elliptica D.Don in vain, with root or all herbal medicine.Autumn excavates, and cleans and dries.Clearing away heat-damp and promoting diuresis, suppressing the hyperactive liver function of gallbladder promoting.For acute icterohepatitis, cholecystitis, gastritis, dizziness headache, toothache.The present invention is with all herbal medicine.
The stem and leaf of Caulis et folium cryptotaeniae japonicae samphire Caulis et folium cryptotaeniae japonicae.Formal name used at school CryptotaeniajaponicaHassk., antiinflammatory, removing toxic substances, invigorates blood circulation, detumescence.Control pneumonia, pulmonary abscess, gonorrhea, hernia, acute toothache, carbuncle furuncle swells, herpes zoster, skin pruritus.
Geum aleppicum is Rosaceae avens geum aleppicum Geum aleppicum Jacq., is used as medicine with herb or root.Summer excavates, and chopping is dried.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.For enteritis, dysentery, infantile convulsion, lumbago and skelalgia, traumatic injury, menoxenia, leucorrhea; Furuncle is controlled in external, carbuncle.The present invention is with all herbal medicine.
Herba Stenolomatis Chusani is Lindsaeaceae Folium Stenolomatis platymiscium Folium Stenolomatis Stenoloma chusanum (L.) Ching, with all herbal medicine.The four seasons can adopt, and Xia Qiu is better.Clean, dry or using fresh herb.Hardship, cold.Heat-clearing and toxic substances removing, dampness removing.For cold, fever, cough, tonsillitis, parotitis, enteritis, dysentery, hepatitis, alimentary toxicosis, pesticide intoxication; Burn and scald is controlled in external, skin eczema.
Beneficial effect: the medicine that the present invention obtains can safe and effective treatment bacterial pneumonia.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, specific embodiment 1: take Herba Ceropegiae Christensenianae 14g, Radix Cotoneastri Perpusillae 12g, Folium Sophorae viciifoliae 15g, Mentha spicata L. 16g, Rhizoma alpiniae pumilae 20g, Herba Anaphalidis 12g, Herba stachydis kouyangensis 14g, Radix Caesalpiniae Radicis 15g, Folium Aeschynomenes indicae 16g, Rhodobryum roseum Limpr. 10g, Rhizoma Polygoni coriacei 12g, Herba Stylophori Lasiocapi 14g, Herba Maianthemi Bifolii 15g, Mus tooth half 13g, Radix haleniae ellipticae 13g, Caulis et folium cryptotaeniae japonicae 8g, geum aleppicum 12g, Herba Stenolomatis Chusani 15g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.Be used for the treatment of bacterial pneumonia.Oral, every bu is taken for twice sooner or later.
2, specific embodiment 2: take Herba Ceropegiae Christensenianae 14g, Radix Cotoneastri Perpusillae 12g, Folium Sophorae viciifoliae 15g, Mentha spicata L. 16g, Rhizoma alpiniae pumilae 20g, Herba Anaphalidis 12g, Herba stachydis kouyangensis 14g, Radix Caesalpiniae Radicis 15g, Folium Aeschynomenes indicae 16g, Rhodobryum roseum Limpr. 10g, Rhizoma Polygoni coriacei 12g, Herba Stylophori Lasiocapi 14g, Herba Maianthemi Bifolii 15g, Mus tooth half 13g, Radix haleniae ellipticae 13g, Caulis et folium cryptotaeniae japonicae 8g, geum aleppicum 12g, Herba Stenolomatis Chusani 15g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, add starch, technique is granulated routinely, must meet the granule of adult normal's 1 day consumption.Be used for the treatment of bacterial pneumonia.Oral, every bu is taken for twice sooner or later.
3, specific embodiment 3: take Herba Ceropegiae Christensenianae 14g, Radix Cotoneastri Perpusillae 12g, Folium Sophorae viciifoliae 15g, Mentha spicata L. 16g, Rhizoma alpiniae pumilae 20g, Herba Anaphalidis 12g, Herba stachydis kouyangensis 14g, Radix Caesalpiniae Radicis 15g, Folium Aeschynomenes indicae 16g, Rhodobryum roseum Limpr. 10g, Rhizoma Polygoni coriacei 12g, Herba Stylophori Lasiocapi 14g, Herba Maianthemi Bifolii 15g, Mus tooth half 13g, Radix haleniae ellipticae 13g, Caulis et folium cryptotaeniae japonicae 8g, geum aleppicum 12g, Herba Stenolomatis Chusani 15g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, add starch, technique is granulated routinely, and tabletting, can obtain the tablet meeting adult normal's 1 day consumption.Be used for the treatment of bacterial pneumonia.Oral, every bu is taken for twice sooner or later.
4. the present invention is to the clinical research of bacterial pneumonia
4.1, physical data: the out-patient collecting 80 routine bacterial pneumonias between inventor's in JIUYUE, 2010 in December ,-2013 altogether, age 12-32 year, the course of disease 1-3 week.Be divided at random: treatment group 50 example, blank group 30 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
Diagnostic criteria: (1) chest X-ray: most common manifestation is that bronchopneumonia type changes, usually the determination of pneumonia cause of disease is helpless to, but suggested by some feature can have diagnosis, as lobe of the lung consolidation, cavity is formed or relatively large hydrothorax is more common in bacterial pneumonia.Staphylococcal pneumonia can cause the necrosis of obvious lung tissue, lung qi capsule, pulmonary abscess and empyema.Gram negative bacillus pneumonia, often in LLB pneumonia type, easily forms multiple little vomica.(2) bacteriology checking: expectorant or hydrothorax plate coating checking, cultivates pathogenic bacterium and antibiotic sensitivity test. and continuous be for 2,3 times same bacterial growth, and the probability of pathogenic bacterium is large, only once positive or be repeatedly that different bacterium grows, then poor reliability.Bacterial concentration >=107cfa/ml is pathogenic bacterium, and 105 ~ 107cfa/ml is suspicious, and <105cfa/ml mostly is contaminated bacteria.(3) blood test: numeration of leukocyte and neutrophilic granulocyte generally all increase, can have shift to left, and old or several cases numeration of leukocyte can not increase.(4) immunologic test: with immunofluorescence, elisa, the methods such as counter immunoelectrophoresis detect antigen or the antibody of serum pathogen, help diagnosis.The detection of polymerase chain reaction to pathogen has certain meaning.(5) other check row blood gas analysis if desired, the coherence check such as Liver and kidney function, serum electrolyte.
4.2, test method
4.2.1 the oral the present invention for the treatment of group is according to the obtained capsule of specific embodiment 1, sooner or later each once.15 days courses for the treatment of.
4.2.2 blank group oral placebo capsule, sooner or later respectively once.15 days courses for the treatment of.
4.3, criterion of therapeutical effect and therapeutic outcome
4.3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and test chamber inspection is normal.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, lab testing improvement or normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
4.3.2 statistical result is treated in table 1.
Table 1 liang group comparitive study
Group n Recovery from illness Take a turn for the better Invalid Total effective rate (%)
Treatment group 50 26 16 8 84
Blank group 30 5 1 24 20
Visible, the medicine that the present invention obtains can safe and effective treatment bacterial pneumonia.

Claims (2)

1. treat the Chinese medicine composition of bacterial pneumonia for one kind, it is characterized in that, it is prepared by the raw material of following parts by weight: Herba Ceropegiae Christensenianae 14 parts, Radix Cotoneastri Perpusillae 12 parts, Folium Sophorae viciifoliae 15 parts, Mentha spicata L. 16 parts, Rhizoma alpiniae pumilae 20 parts, Herba Anaphalidis 12 parts, Herba stachydis kouyangensis 14 parts, Radix Caesalpiniae Radicis 15 parts, Folium Aeschynomenes indicae 16 parts, Rhodobryum roseum Limpr. 10 parts, Rhizoma Polygoni coriacei 12 parts, Herba Stylophori Lasiocapi 14 parts, Herba Maianthemi Bifolii 15 parts, Mus tooth half 13 parts, Radix haleniae ellipticae 13 parts, Caulis et folium cryptotaeniae japonicae 8 parts, geum aleppicum 12 parts, Herba Stenolomatis Chusani 15 parts.
2. treat the application of Chinese medicine composition in the medicine for the treatment of bacterial pneumonia of bacterial pneumonia as claimed in claim 1.
CN201410556981.8A 2014-10-20 2014-10-20 Traditional Chinese medicine composition for treating bacterial pneumonia as well as preparation method and application thereof Pending CN104288642A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105168329A (en) * 2015-10-09 2015-12-23 南京市栖霞区回春堂电子商务咨询中心 Extraction method and application of plant composition containing kudzuvine roots
CN105497723A (en) * 2016-01-22 2016-04-20 封春香 Traditional Chinese medicine preparation for treating bacterial pneumonia and preparation method thereof

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Title
史大卓等编著: "《中医内科辨病治疗学》", 30 August 1995, 北京：科学技术文献出版社 *
姚小鹏，陈喆主编: "《乡村医生用书 呼吸系统疾病诠疗手册》", 30 May 2010, 北京：金盾出版社 *
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105168329A (en) * 2015-10-09 2015-12-23 南京市栖霞区回春堂电子商务咨询中心 Extraction method and application of plant composition containing kudzuvine roots
CN105497723A (en) * 2016-01-22 2016-04-20 封春香 Traditional Chinese medicine preparation for treating bacterial pneumonia and preparation method thereof

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Application publication date: 20150121