CN104258159A - Ointment for treating skin eczema as well as preparation method and application thereof - Google Patents
Ointment for treating skin eczema as well as preparation method and application thereof Download PDFInfo
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- CN104258159A CN104258159A CN201410548704.2A CN201410548704A CN104258159A CN 104258159 A CN104258159 A CN 104258159A CN 201410548704 A CN201410548704 A CN 201410548704A CN 104258159 A CN104258159 A CN 104258159A
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/69—Polygalaceae (Milkwort family)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/88—Liliopsida (monocotyledons)
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- A61K9/00—Medicinal preparations characterised by special physical form
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- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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Abstract
The invention provides ointment for treating skin eczema. The ointment is prepared from the following raw materials in parts by weight: 14 parts of cheilosoria chusana, 12 parts of sporobolus elongatus, 15 parts of radix linderae reflexae, 8 parts of hairyvein agrimony root, 12 parts of amaranthus tricolor, 14 parts of ceylon cynoglossum, 16 parts of iron whip, 12 parts of clerodendrum fortunatum root, 9 parts of white aralis bark, 12 parts of arundina graminifolia, 14 parts of filiform cassytha herb, 12 parts of hibiscus mutabilis, 14 parts of four-leaf clover, 15 parts of large-leaved stonecrop, 12 parts of lateral-flower milkwort herb, 16 parts of seashore calystegia root, 14 parts of trigonotis peduncularis, 17 parts of thalictrum simplex, 12 parts of tiarella polyphylla and 15 parts of eupatorium root. The ointment can be used for treating the skin eczema.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of ointment machin preparation method and application treating skin eczema.
Background technology
Skin eczema is infected by human papillomavirus (HPV) and causes, and is apt to occur in teen-age disease of viral infection.Clinical manifestation is color of the leather or peach flat pimple, and be more common in face and the back of the hand, without obvious subjective symptoms, the course of disease is chronic.By direct or indirect contagion.Be apt to occur in teenager, can onset suddenly, skin lesion is mainly in face, the back of the hand, arm, shows as the flat pimple differed in size, slightly swells, smooth surface, rounded, oval or polygon, boundary is clear, can dense distribution or owing to scratch and in the linear alignment local, general no conscious sympton, the conscious slight pruritus of some patients.The course of disease is chronic process, for many years sustainable, and some patients can take a turn for the better voluntarily.Epidermis basket shape hyperkeratosis companion parakeratosis, acanthosis, the visible more physaliphore in epidermis top, karyon basophilic, granular layer is evenly plump.Corium changes not obvious.Lack effective medicine at present.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of ointment machin preparation method and application treating skin eczema.
Technical scheme: the object of the invention is by following scheme realize:
Treat an ointment for skin eczema, it is prepared by the raw material of following parts by weight: Herba Cheilanthes chusane 14 parts, Mus tail chestnut 12 parts of, Radix Linderae Reflexae 15 parts, Radix Agrimoniae 8 parts, Herba amaranthi tricoloris 12 parts, Cortex cynoglossi zeylanici radicis 14 parts, Herba lespedezae floribundae 16 parts, Radix Clerodendri Fortunati 12 Fen, Cortex araliae chinensis 9 parts, Herba Murdanniae Divergentis 12 parts, Herba Casythae Filiformis 14 parts, Flos Hibisci Mutabilis 12 parts, Herba Galii Bungei 14 parts, Herba Sebi drymarioidis 15 parts, Herba Polygalae lateriflorae 12 parts, Radix Calystegiae Soldanellae 16 parts, Herba Trigonotidis peduncularis 14 parts, Radix Thalictri brevipedis 17 parts, Herba tiarellae polyphyllae 12 parts, Herba eupatorii japonici 15 parts.
The application of ointment in preparation treatment skin eczema medicine of described treatment skin eczema.
In the present invention, Herba Cheilanthes chusane is that Sinopteridaceae vegetable hair axle is cracked rice the herb of Herba pteridii latiusculi.Latin is called Pteris multifda poir, property mildly bitter flavor; Cold; Nontoxic, control dysentery, urine pain, foot is soft unable, fever with pantalgia, laryngalgia, venom, carbuncle furuncle and phyma scrofula.
Mus tail chestnut, formal name used at school: Sporobolus fertilis (Steud.) W.D.Clayt., belongs to Poales, grass family perennial plant.Produce the provinces and regions such as East China, Central China, southwest, Shaanxi, Gansu, Tibet; Be born in the roadside, field of height above sea level 120-2600 rice, patana and mountain valley to wet place and sylvan life.Be distributed in the ground such as India, Burma, Sri Lanka, Thailand, Vietnam, Malaysia, Indonesia, Philippine, Japan, the Soviet Union.Nature and flavor: sweet light are flat.Function cures mainly: heat clearing away, removing heat from blood, removing toxic substances, diuresis.Control epidemic encephalitis, encephalitis b unconsciousness due to high fever, infectious hepatitis, dysentery, pyretic stranguria, hematuria.The present invention is with all herbal medicine.
Radix Linderae Reflexae is root or the root bark of canella Shan Kashihara, has effect of hemostasis, detumescence, circulation of qi promoting, pain relieving.
Radix Agrimoniae is the root of rosaceous plant Agrimony.Gather after autumn, clean, except removing LU.Acrid in the mouth is puckery, temperature, nontoxic.Control dysentery, women's amenorrhea, toxic swelling, expelling tenia.
Herba amaranthi tricoloris, Latin literary fame Amaranthus tricolor, annual herb, stem is upright, and high 14-45 centimetre, single or branch, by glandular hair.Inferior leads to life, upper leaf alternate, width egg shape, Long Circle and lanceolar, long 2-7.5 centimetre, the sharp point in top, base portion is narrow or half armful of stem gradually, Quan Yuan, and there is pubescence on blade face; Original producton location is Tropical Asian area.Herba amaranthi tricoloris is Amaranthaceae annual herb plant, plant height 80-100 centimetres, and stem is upright, few branch.Leaf alternate, Pedicellus et Pericarpium Trapae shape is avette to lanceolar.Spend minimum, spike race is born between axil, and seed black is glossy.Originate in India.There is cultivation China various places.Control dysentery, spit blood, metrorrhagia.The present invention is with all herbal medicine.
Cortex cynoglossi zeylanici radicis is Magnoliaceae Radix Schisandrae Bicoloris platymiscium Cortex cynoglossi zeylanici radicis Schisandra propinqua (Wall.) Hook.f.et Thoms.var.sinensis Oliv., is used as medicine with root.Autumn uproots, and cleans and dries; Sweet, pungent, flat, expelling wind and activating blood circulation, removing toxic substances and promoting subsidence of swelling, pain relieving.Root: rheumatic numbness, traumatic injury, stomachache, menoxenia, rhomboembolia type straw is scorching.
Herba lespedezae floribundae is the herb of leguminous plant Lespedeza floribunda.Classification system Lespedeza floribunda Bge, puckery, cool in nature, treating malaria disease.
Radix Clerodendri Fortunati is root or the root bark of Verbenaceae Fructus Seu Herba Pubescentis, and Classification system Clerodendron fortunatum L, has the effects such as heat clearing away, removing toxic substances, removing heat from blood, pain relieving, the symptom such as cure mainly cold, fever, bloody dysentery, skin ulcer scabies, scrofula, swell and ache.
Cortex araliae chinensis is the phloem that Wu adds section Zhi Wu Cortex araliae chinensis, dispelling the wind and dampness pathogens arthralgia pain, traumatic injury.
Herba Murdanniae Divergentis, Classification system Arundina graminifolia, the orchid family section, tree orchid race, Folium Bambusae Cymbidium, nature and flavor are bitter, flat.Heat-clearing and toxic substances removing, expelling wind and removing dampness, pain relieving, diuresis.For hepatitis, arthralgia, pain in the low back and legs, stomachache, stranguria, difficulty and pain in micturition, beriberi edema, scrofula, pulmonary tuberculosis, toothache, throat pain, flu, infantile convulsion, infantile malnutrition, cough, alimentary toxicosis, gets injured by a fall, venom, traumatic hemorrhage.The present invention is with all herbal medicine.
Herba Casythae Filiformis is the herb of canella dodder laurel.Latin name: Cassytha filiformis L. clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Treating the liver heat is become thin, cough due to lung-heat, jaundice, dysentery, epistaxis, stranguria with blood, carbuncle, scabies, scalds.
Flos Hibisci Mutabilis is Malvaceae Hibiscus fallen leaves shrubs.Classification system Hibiscus mutabilis, has the effects such as heat clearing away, removing toxic substances, detumescence.The present invention is used as medicine with Herb.
Herba Galii Bungei is the rare mutation of Clover plant (comprising Trifolium and Alfalfa), also has more than five leaves, is at most 18 leaves.Classification system Lotus corniculatus L., taste is sour-sweet, cool property, clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.For cold, fever, enteritis, urinary tract infection, lithangiuria.The present invention is with all herbal medicine.
Herba Sebi drymarioidis is the herb of crassulaceae plants great Ye flame grass.Clearing away heat and cooling blood, subduing swelling and detoxicating.Control haematemesis, hemoptysis.
Herba Polygalae lateriflorae is the herb of milk wort side raw flower Radix Polygalae.Heat-clearing and toxic substances removing, YIN nourishing arresting sweating, synthetism.Control night sweat, fracture.
Radix Calystegiae Soldanellae is the root of renal lobe sky sword, is used for the treatment of the symptoms such as rheumatic arthralgia.
Herba Trigonotidis peduncularis, formal name used at school: Trigonotis peduncularis is the plant that Boraginaceae Herba Trigonotidis peduncularis belongs to, and annual herb is high 5 ~ 30 centimetres; Stem is usually from base portion branch, very thin.Cochlear, ellipse or lance-shaped lobule alternate, base portion is narrow, the calm coarse wool of the equal tool in two sides.Spend and be usually born in racemose side, corolla is blue, and inflorescence top is circumvolution shape.4 pieces of tetrahedroid pyrenes.5 ~ June of florescence.Cure mainly phlegm dyspnea, order disease, cataracta etc.The present invention is with all herbal medicine.
Radix Thalictri brevipedis, latin name Thalictrum simplex L.var.brevipes Hara is the root of ranunculaceae plant T.simplex.Clearing away damp-heat, removing toxic substances.Harness the Yellow River subcutaneous ulcer, dysentery, asthma, measles and pneumonia infection, nasal eczema eyebrow is red, herpes simplex.
Herba tiarellae polyphyllae is Saxifragaceae Herba tiarellae polyphyllae platymiscium Herba tiarellae polyphyllae Tiarella polyphylla D.Don, with all herbal medicine.Xia Qiu gathers, and dries.Hardship, cold.Heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain.For carbuncle furuncle and phyma poison, traumatic injury, hepatitis, cough and asthma.
Herba eupatorii japonici is herb or the root of feverfew mountain orchid.Deliver cold expelling, saturating measles.Control proctoptosis, measles without adequate eruption, lumbago due to cold-damp, cough due to wind and cold.The present invention is with all herbal medicine.
Beneficial effect: the medicine that the present invention obtains can safe and effective treatment skin eczema.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, specific embodiment 1: take Herba Cheilanthes chusane 14g, Mus tail chestnut 12g, Radix Linderae Reflexae 15g, Radix Agrimoniae 8g, Herba amaranthi tricoloris 12g, Cortex cynoglossi zeylanici radicis 14g, Herba lespedezae floribundae 16g, Radix Clerodendri Fortunati 12g, Cortex araliae chinensis 9g, Herba Murdanniae Divergentis 12g, Herba Casythae Filiformis 14g, Flos Hibisci Mutabilis 12g, Herba Galii Bungei 14g, Herba Sebi drymarioidis 15g, Herba Polygalae lateriflorae 12g, Radix Calystegiae Soldanellae 16g, Herba Trigonotidis peduncularis 14g, Radix Thalictri brevipedis 17g, Herba tiarellae polyphyllae 12g, Herba eupatorii japonici 15g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, add adjuvant, be prepared into ointment according to a conventional method, the ointment of adult normal's 1 day consumption must be met.Be used for the treatment of skin eczema.External application, twice external sooner or later of every bu.
2, the present invention is to the clinical research of skin eczema
2.1, physical data: inventor collects the out-patient of 50 routine skin eczemas-2013 years in Mays, 2012 altogether between JIUYUE, age 18-25 year, the course of disease 1-4 week.Be divided at random: treatment group 30 example, blank group 20 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
Skin eczema diagnostic criteria:
2.1.1 main according to medical history, erythra form and the course of disease.The skin lesion of general eczema is pleomorphism, and based on erythema, pimple, papulovesicle, erythra central authorities obviously, scatter gradually towards periphery, indefinite border, and diffusivity, has and ooze out tendency, and chronic person then has infiltration plump.The course of disease is irregular, in recurrent exerbation, and acute pruritus.
2.1.2 skin lesion is just the pimple of most intensive foxtail millet grain size, papulovesicle or phlysis, and substrate flushing, merges in flakes gradually, and owing to scratching, pimple, papulovesicle or vesicle top are oozed out and little rotten to the corn face in obvious point-like after scratching, blur margin.As secondary infection, inflammation is more obvious, can form pustule, pus crusts, folliculitis, furuncle etc.Conscious violent pruritus.After being apt to occur in women's head-ornaments, ear, distal limbs, scrotum, crissum etc., multipair title is issued.
2.2, test method
2.2.1 the oral external the present invention for the treatment of group is according to the obtained ointment of specific embodiment 1, sooner or later each once.15 days courses for the treatment of.
2.2.2 blank group external placebo ointment, sooner or later respectively once.15 days courses for the treatment of.
2.3, criterion of therapeutical effect and therapeutic outcome
2.3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and test chamber inspection is normal.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, lab testing improvement or normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
2.3.2 statistical result is treated in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) |
| Treatment group | 30 | 18 | 18 | 4 | 86.7 |
| Blank group | 20 | 1 | 2 | 18 | 13.3 |
Visible, the medicine that the present invention obtains can safe and effective treatment skin eczema.
Claims (2)
1. treat the ointment of skin eczema for one kind, it is characterized in that, it is prepared by the raw material of following parts by weight: Herba Cheilanthes chusane 14 parts, Mus tail chestnut 12 parts of, Radix Linderae Reflexae 15 parts, Radix Agrimoniae 8 parts, Herba amaranthi tricoloris 12 parts, Cortex cynoglossi zeylanici radicis 14 parts, Herba lespedezae floribundae 16 parts, Radix Clerodendri Fortunati 12 Fen, Cortex araliae chinensis 9 parts, Herba Murdanniae Divergentis 12 parts, Herba Casythae Filiformis 14 parts, Flos Hibisci Mutabilis 12 parts, Herba Galii Bungei 14 parts, Herba Sebi drymarioidis 15 parts, Herba Polygalae lateriflorae 12 parts, Radix Calystegiae Soldanellae 16 parts, Herba Trigonotidis peduncularis 14 parts, Radix Thalictri brevipedis 17 parts, Herba tiarellae polyphyllae 12 parts, Herba eupatorii japonici 15 parts.
2. treat the application of ointment in treatment skin eczema medicine of skin eczema as claimed in claim 1.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104825738A (en) * | 2015-06-06 | 2015-08-12 | 淄博齐鼎立专利信息咨询有限公司 | Skin eczema treating ointment and preparation method and application thereof |
| CN105832854A (en) * | 2016-05-18 | 2016-08-10 | 庄章彬 | Application of four-leaved clover juice to preparation of medicine for treating toothache |
| CN106110044A (en) * | 2016-08-27 | 2016-11-16 | 董加利 | A kind of Chinese medicinal ointment treating eczema |
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| CN103877250A (en) * | 2014-04-16 | 2014-06-25 | 李国宣 | Chinese traditional medicine composition for curing skin eczema pruritus and preparation method of composition |
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| CN103877250A (en) * | 2014-04-16 | 2014-06-25 | 李国宣 | Chinese traditional medicine composition for curing skin eczema pruritus and preparation method of composition |
| CN103893376A (en) * | 2014-04-16 | 2014-07-02 | 李国宣 | Traditional Chinese medicine composition for treating skin eczema and bleb and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104825738A (en) * | 2015-06-06 | 2015-08-12 | 淄博齐鼎立专利信息咨询有限公司 | Skin eczema treating ointment and preparation method and application thereof |
| CN105832854A (en) * | 2016-05-18 | 2016-08-10 | 庄章彬 | Application of four-leaved clover juice to preparation of medicine for treating toothache |
| CN106110044A (en) * | 2016-08-27 | 2016-11-16 | 董加利 | A kind of Chinese medicinal ointment treating eczema |
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