CN104288371A - Traditional Chinese medicine composition for treating perennial allergic rhinitis, preparation method and application - Google Patents
Traditional Chinese medicine composition for treating perennial allergic rhinitis, preparation method and application Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition for treating perennial allergic rhinitis. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 16 parts of Abelia chinensis R. Br., 13 parts of Abelia engleriana (Graebn.) Rehd., 12 parts of Impatiens pritzelii Hook. f. var.hupehensis hook. f., 15 parts of Ishige foliacea Okam., 14 parts of Juncus articulatus L., 13 parts of Kalimeris integrifolia Turcz.ex DC., 15 parts of Kochia scoparia (L.) Schrad. Var.sieversiana (Pall.) Ulbr. ex Aschers. et Graebn., 12 parts of Thesium longifolium Turcz., 14 parts of gerbera, 13 parts of Oreocharis benthamii, 13 parts of Adiantum flabellulatum L. A. fuscum, 12 parts of Stachys baicalensis Fisch. ex Benth., 8 parts of Limnophila aromatica (Lam.) Merr. Limnophila gratissima Blume, 11 parts of Pachysandra terminalis Sieb. et Zucc., 14 parts of Murraya tetramera Huang and 10 parts of Crossostepium chinense (L.) Makino. The traditional Chinese medicine composition can be used for treating the perennial allergic rhinitis.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition and the preparation method and application that treat perennial allergic rhinitis.
Background technology
The symptom of perennial allergic rhinitis (PAR) is similar to seasonal allergic rhinitis, but heavy time light during perennial allergic rhinitis's symptom, is difficult to expect, can appear at any season.In the clinical manifestation of perennial allergic rhinitis, conjunctivitis is uncommon, often has nasal obstruction, causes Eustachian tube to block, and causes audition abnormal, especially child.Should differentiate with sinusitis and nasal polyp.Sinusitis and nasal polyp may be the complication of allergic rhinitis.Have chronic nasal obstruction, watery nasal discharge but without sinusitis, nasal polyp or other anaphylactogens because of people may suffer from atrophic rhinitis in various degree, it is not caused by allergy.The allergen of perennial allergic rhinitis may be dirt demodicid mite, feather, animal scurf or mycete.Lack effective medicine at present.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine composition and the preparation method and application that treat perennial allergic rhinitis.
Technical scheme: the object of the invention is by following scheme realize:
Treat a perennial allergic rhinitis's Chinese medicine composition, it is prepared by the raw material of following parts by weight: Abelia Chinensis R. Br. 16 parts, logical stalk spend 13 parts, cool water harm 12 parts, lobate Ishige okamurae Yendo 15 parts, little Hua Medulla Junci 14 parts, Kalimeris integrifolia 13 parts, Kochia sieversiana 15 parts, Herba Thesii Longifolii 12 parts, Herba Leibnitziae 14 parts, 13 parts, lotus on stone, Herba Adianti Flabellulati 13 parts, Herba Stachydis 12 parts, cough-relieving grass 8 parts, careless 11 parts green for a long time, tetramerous jasminorange leaf 14 parts, Chinese mugwort in thousand 10 parts.
The application of Chinese medicine composition in the medicine of preparation treatment perennial allergic rhinitis of described treatment perennial allergic rhinitis.
Abelia Chinensis R. Br. in the present invention is Caprifoliaceae, Abelia.Latin is called Abelia chinensis R.Br., produces East China, Central-South and southwest.Stem, leaf, herb: heat-clearing and toxic substances removing, hemostasis.For having loose bowels, children's's infantile malnutrition worm-eaten tooth, traumatic injury, influenza.Oral aphthae in children is controlled in external, parotitis.The present invention is with all herbal medicine.
Logical stalk flower, Latin is called Abelia engleriana (Graebn.) Rehd., Abelia, section's Chinese name: Caprifoliaceae, root: regulating QI to relieve pain, heat clearing and damp drying.For toothache, high heat, acute catarrhal conjunctivitis.Fruit or flower: wind-damp dispelling, relieving heat toxin.For rheumatism bones and muscles pain, red and swollen for pain skin ulcer outward.The present invention is used as medicine with root.
Cool water harm, Latin is called Impatiens pritzelii Hook.f.var.hupehensis Hook.f., is the root of the Radix Euphorbiae Pekinensis, euphorbia plant southwest.Produce Hubei, Sichuan.Root stock: expelling wind and removing dampness, dissipating blood stasis for subsidence of swelling, pain relieving, hemostasis, heat-clearing and toxic substances removing.For rheumatalgia, numb limbs and tense tendons, arthroncus, stomachache, dyspeptic abdominal distention, has loose bowels, menoxenia, dysmenorrhea, dysentery.Flower, herb: for traumatic injury, phoenix wets arthralgia.
Lobate Ishige okamurae Yendo, Latin is called Ishige foliacea Okam., belongs to Phaeophyta (Phaeophyta), the large-scale edible algae of iron nail Lepidium (Ishige), is distributed in the subtropical zone property Sargassum that the ground such as Fujian are coastal, produces south China and Zhejiang, Fujian, marine site, Taiwan.Frond: heat-clearing and toxic substances removing, eliminates the phlegm, hard masses softening and resolving, ascarifuge.For goiter, scrofula, throat pain.The present invention is used as medicine with full frond.
Little Hua Medulla Junci is the plant of rush family sharp-flowered rush.Latin is called Juncus articulatus L., produces northeast, North China, northwest, East China and Sichuan.Herb: clearing away heat and promoting diuresis, relieving restlessness.The present invention is with all herbal medicine.
Kalimeris integrifolia, Latin is called Kalimeris integrifolia Turcz.ex DC., is that Compositae Herba Kalimeridis belongs to herbaceos perennial, produces northeast, North China, Central China, East China and Shaanxi, Sichuan, Guizhou.Herb and root: heat-clearing and toxic substances removing, regulate the flow of vital energy and help digestion, hemostasia and detumescence, dampness removing.Inflorescence: clearing away heat to improve acuity of vision.For oculopathy.The present invention is with all herbal medicine.
Kochia sieversiana is the mutation of under Chenopodiaceae Kochia.Latin is called Kochia scoparia (L.) Schrad.var.sieversiana (Pall.) Ulbr.ex Aschers.et Graebn., produces northeast, North China, northwest.Fruit: clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching.The present invention is with all herbal medicine.
Herba Thesii Longifolii is that Santalaceae plant comes into leaves the herb of Herba Thesii, and perennial herb, height is 50cm about.Stem clusters, and has obvious longitudinal furrow.Leaf stockless.Linear, long 4-4.5cm, wide 2.5mm, two ends are gradually sharp, have 3 arteries and veins.Expelling wind and clearing away heat, spasmolytic.
Herba Leibnitziae is the herb of feverfew Herba Leibnitziae, perennial herb.Be born in the dark and damp places such as roadside, hillside, Lin Bian, meadow, limes marginis, be distributed in the ground such as Chinese north and south.There is clearing away heat-damp and promoting diuresis; Effect of removing toxic substances and promoting subsidence of swelling.Cure mainly cough due to lung-heat; Damp-heat dysentery; Pyretic stranguria; Rheumatic arthritis; Carbuncle furuncle and phyma poison; Ecthyma; Early venom; Burn and scald; Traumatic hemorrhage.
Shi Shanglian is Gesneriaceae herbaceos perennial.Classification system Oreocharis benthamii, controls the diseases such as traumatic injury.Removing damp-heat, diuretic softening the hard mass, reducing swelling and alleviating pain.Treating hepatocirrhosis, ascites, summer-heat is thirsty.Treating swelling and pain by traumatic injury is controlled in external, furuncle swelling toxin.The present invention is with all herbal medicine.
Herba Adianti Flabellulati is herb or the rhizome of adiantaceae plant flabellum venushair fern, and the whole year can adopt, using fresh herb or dry.Herb, containing flavonoid glycoside, organic acid, aminoacid, phenols and saccharide, can be used for antibacterial, hemostasis.Classification system Adiantum flabellulatum L.A.fuscum.The present invention is with all herbal medicine.
Herba Stachydis is Labiatae betony Herba Stachydis Stachys baicalensis Fisch.ex Benth., with all herbal medicine.Xia Qiu gathers, and dries.To dispel the wind removing toxic substances, hemostasis.For flu, laryngopharynx swelling and pain, spits blood, epistaxis, metrorrhagia, hyperchlorhydria; Furuncle toxic swelling is controlled in external.
Cough-relieving grass, Classification system Limnophila aromatica (Lam.) Merr.Limnophila gratissima Blume, with all herbal medicine.The whole year can adopt, and cleans, using fresh herb or dry.Clearing away lung-heat to relieve cough, removing toxic substances and promoting subsidence of swelling.For flu, cough, pertussis, venom, carbuncle pyogenic infections from tumour or sore.
Grass green for a long time is Buxaceae powder stamen Buxus plant top stamen Herba Pachysandrae Stylosae Pachysandra terminalis Sieb.et Zucc., with all herbal medicine.The whole year can adopt, and cleans cutting, dries.Dispelling wind stopping cough, relaxing muscles and tendons and activating QI and blood in the collateral, adjusting meridian and stopping leukorrhea.For chronic tracheitis, rheumatic arthritis, spasm of the calf, leucorrhea, amenorrhea, psychosis dysphoria.
Tetramerous jasminorange leaf is Rutaceae Murraya plant tetramerous jasminorange leaf Murraya tetramera Huang, is used as medicine with Ye Hegen.The picking leaves of autumn in summer, autumn adopts root, cleans cutting, all can using fresh herb or dry in the shade for subsequent use.Expelling pathogenic wind from the body surface, promoting the circulation of QI to relieve pain, promoting blood circulation to remove blood stasis.For cold, fever, bronchitis, asthma, rheumatic numbness, bones and muscles pain, traumatic injury swelling and pain due to blood stasis, skin pruritus, eczema, venom, malaria, stomachache, edema etc.The present invention is used as medicine with leaf.
Within thousand, Chinese mugwort is Compositae Hibisci Mutabilis Dendranthema Chinese mugwort Crossostephium chinense (L.) Makino in thousand, is used as medicine with root, leaf.The whole year can adopt, and cleans, using fresh herb or dry.: expelling wind and removing dampness, removing toxic substances and promoting subsidence of swelling, relieving cough and resolving phlegm.For anemofrigid cold, measles, Fengshi Guanjie pain, stomachache, bronchitis, pertussis, furuncle swelling toxin, mastitis.The present invention is used as medicine with leaf.
Beneficial effect: the medicine that the present invention obtains can safe and effective treatment perennial allergic rhinitis.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, specific embodiment 1: take lotus 13g, Herba Adianti Flabellulati 13g, Herba Stachydis 12g, cough-relieving grass 8g, careless 11g green for a long time, tetramerous jasminorange leaf 14g, Chinese mugwort 10g in thousand on Abelia Chinensis R. Br. 16g, logical stalk flower 13g, cool water harm 12g, lobate Ishige okamurae Yendo 15g, little Hua Medulla Junci 14g, Kalimeris integrifolia 13g, Kochia sieversiana 15g, Herba Thesii Longifolii 12g, Herba Leibnitziae 14g, stone, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.Be used for the treatment of perennial allergic rhinitis.Oral, every bu is taken for twice sooner or later.
2, specific embodiment 2: take lotus 13g, Herba Adianti Flabellulati 13g, Herba Stachydis 12g, cough-relieving grass 8g, careless 11g green for a long time, tetramerous jasminorange leaf 14g, Chinese mugwort 10g in thousand on Abelia Chinensis R. Br. 16g, logical stalk flower 13g, cool water harm 12g, lobate Ishige okamurae Yendo 15g, little Hua Medulla Junci 14g, Kalimeris integrifolia 13g, Kochia sieversiana 15g, Herba Thesii Longifolii 12g, Herba Leibnitziae 14g, stone, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, add starch, technique is granulated routinely, must meet the granule of adult normal's 1 day consumption.Be used for the treatment of perennial allergic rhinitis.Oral, every bu is taken for twice sooner or later.
3, specific embodiment 3: take lotus 13g, Herba Adianti Flabellulati 13g, Herba Stachydis 12g, cough-relieving grass 8g, careless 11g green for a long time, tetramerous jasminorange leaf 14g, Chinese mugwort 10g in thousand on Abelia Chinensis R. Br. 16g, logical stalk flower 13g, cool water harm 12g, lobate Ishige okamurae Yendo 15g, little Hua Medulla Junci 14g, Kalimeris integrifolia 13g, Kochia sieversiana 15g, Herba Thesii Longifolii 12g, Herba Leibnitziae 14g, stone, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, add starch, technique is granulated routinely, and tabletting, can obtain the tablet meeting adult normal's 1 day consumption.Be used for the treatment of perennial allergic rhinitis.Oral, every bu is taken for twice sooner or later.
4. the present invention is to the clinical research of perennial allergic rhinitis
4.1, physical data: inventor collects the out-patient of 60 routine perennial allergic rhinitises-2012 years in Augusts, 2010 altogether between December, age 15-36 year, course of disease 1-3.Be divided at random: treatment group 40 example, blank group 20 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
Diagnostic criteria: (1) scores condition: 1. perennial onset, there are sneeze (at every turn continuous more than 3), snivel and nasal mucosa swelling three main clinical manifestation, number of days of falling ill in 1 year is accumulative more than 6 months, and in one day, disease time is accumulative more than 0.5 hour; 2. the course of disease at least one year.(2) scoring criteria: have clear and definite inhalation (inhalatio) sensitinogen clue, a guy and/or family's anaphylactic disease history, there is typical sings and symptoms stage of attack, each note 1 point, totally 3 points.Allergen skin test positive reaction, has at least a kind of for more than (++) or (++); Specific IgE antibody detects positive or allergen nasal provocation test is positive, and meets with tuerculoderma and medical history, each gets 2 points, totally 4 points.Nasal smear checks that eosinophilic granulocyte is positive and/or nasal mucosa scraping blade mastocyte (basophil) is positive and obtains 1 point.Score 6 ~ 8 points is diagnosed as perennial allergic rhinitis, and 3 ~ 5 are divided into suspicious allergic rhinitis, and 0 ~ 2 point may be anallergic rhinitis.
4.2, test method
4.2.1 the oral the present invention for the treatment of group is according to the obtained capsule of specific embodiment 1, sooner or later each once.15 days courses for the treatment of.
4.2.2 blank group oral placebo capsule, sooner or later respectively once.15 days courses for the treatment of.
4.3, criterion of therapeutical effect and therapeutic outcome
4.3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and test chamber inspection is normal.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, lab testing improvement or normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
4.3.2 statistical result is treated in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) |
| Treatment group | 40 | 18 | 16 | 6 | 85 |
| Blank group | 20 | 1 | 2 | 17 | 13.3 |
Visible, the medicine that the present invention obtains can safe and effective treatment perennial allergic rhinitis.
Claims (2)
1. treat the Chinese medicine composition of perennial allergic rhinitis for one kind; it is characterized in that, it is prepared by the raw material of following parts by weight: Abelia Chinensis R. Br. 16 parts, logical stalk spend 13 parts, cool water harm 12 parts, lobate Ishige okamurae Yendo 15 parts, little Hua Medulla Junci 14 parts, Kalimeris integrifolia 13 parts, Kochia sieversiana 15 parts, Herba Thesii Longifolii 12 parts, Herba Leibnitziae 14 parts, 13 parts, lotus on stone, Herba Adianti Flabellulati 13 parts, Herba Stachydis 12 parts, cough-relieving grass 8 parts, careless 11 parts green for a long time, tetramerous jasminorange leaf 14 parts, Chinese mugwort in thousand 10 parts.
2. treat the application of Chinese medicine composition in the medicine for the treatment of perennial allergic rhinitis of perennial allergic rhinitis as claimed in claim 1.
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| CN104873872A (en) * | 2015-05-30 | 2015-09-02 | 陈爱华 | Granular formulation for treating perennial allergic rhinitis |
| CN104998109A (en) * | 2015-07-27 | 2015-10-28 | 济南知尔医药科技有限公司 | Traditional Chinese medicine for treating perennial allergic rhinitis |
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| CN1357329A (en) * | 2001-10-29 | 2002-07-10 | 曾咏梅 | Medicine for treating perennial allergic rhinitis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104873872A (en) * | 2015-05-30 | 2015-09-02 | 陈爱华 | Granular formulation for treating perennial allergic rhinitis |
| CN104998109A (en) * | 2015-07-27 | 2015-10-28 | 济南知尔医药科技有限公司 | Traditional Chinese medicine for treating perennial allergic rhinitis |
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