CN104288560A - Ointment for treating verruca plana, as well as preparation method and application thereof - Google Patents
Ointment for treating verruca plana, as well as preparation method and application thereof Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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Abstract
The invention provides ointment for treating verruca plana. The ointment is prepared from the following raw materials in parts by weight: 16 parts of streblus indicus, 12 parts of vitis piasezkii maxim, 14 parts of phyllodium pulchellum, 15 parts of bidens tripartita, 16 parts of agalma delavayi, 10 parts of inula nervosa wall, 16 parts of puccinellia tenuiflora, 14 parts of radix cynanchi bungei, 12 parts of pogonatherum crinitum, 16 parts of suffrutescent securinega twig, 12 parts of beonninghausenia sessilicarpa and 14 parts of calystegia hederacea. The ointment can be used for treating verruca plana.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of ointment machin preparation method and application treating verruca plana.
Background technology
Verruca plana is infected by human papillomavirus (HPV) and causes, and is apt to occur in teen-age disease of viral infection.Clinical manifestation is color of the leather or peach flat pimple, and be more common in face and the back of the hand, without obvious subjective symptoms, the course of disease is chronic.By direct or indirect contagion.Be apt to occur in teenager, can onset suddenly, skin lesion is mainly in face, the back of the hand, arm, shows as the flat pimple differed in size, slightly swells, smooth surface, rounded, oval or polygon, boundary is clear, can dense distribution or owing to scratch and in the linear alignment local, general no conscious sympton, the conscious slight pruritus of some patients.The course of disease is chronic process, for many years sustainable, and some patients can take a turn for the better voluntarily.Epidermis basket shape hyperkeratosis companion parakeratosis, acanthosis, the visible more physaliphore in epidermis top, karyon basophilic, granular layer is evenly plump.Corium changes not obvious.Lack effective medicine at present.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of ointment machin preparation method and application treating verruca plana.
Technical scheme: the object of the invention is by following scheme realize:
Treat an ointment for verruca plana, it is prepared by the raw material of following parts by weight: Pseudostreblus indica Bur. 16 parts, 12 parts, numb sheep rattan, row money set 14 parts, Herba Bidentis Tripartitae 15 parts, fine hair Cortex schefflerae octophyllae 16 parts, Wheeling chrysanthemum 10 parts, Flos Eragrostinis cilianensis 16 parts, Radix Cynanchi Auriculati 14 parts, Herba Melicae Scabrosae 12 parts, Suffrutescent Securinega Twig 16 parts, Herba Boenninghauseniae 12 parts, DAWANHUA 14 parts.
The application of ointment in preparation treatment verruca plana medicine of described treatment verruca plana.
In the present invention, Pseudostreblus indica Bur. is Cortex pseudostrebli indicae bark, and Latin is called Streblus indicus (Bur.) Corner, and Moraceae kidney magpie Pterostyrax arbor, is used as medicine with bark, hemostasis, pain relieving.For digestive tract hemorrhage, stomachache; Traumatic hemorrhage is controlled in external.
Fiber crops sheep rattan is Vitaceae fiber crops sheep rattan Vitis piasezkii Maxim., goes out juice be used as medicine with young stemflow.Heat-clearing and toxic substances removing, dispelling, collateral-activating, pain relieving, hemostasis.For rheumatic arthritis, vomiting, diarrhoea, Peptic Ulcers; Traumatic injury is controlled in external, swells and ache, sore swollen toxin, traumatic hemorrhage, burn and scald.
Row Qian Shuwei pulse family beggar-ticks rows of plants money tree Desmodium pulchellum (L.) Benth., is used as medicine with root and leaf.Xia Qiu gathers, and summer shreds, and dries or using fresh herb.Clearing away heat-damp and promoting diuresis, blood circulation promoting and blood stasis dispelling, hard masses softening and resolving.For cold, fever, malaria, hepatitis, cirrhotic ascites, schistosomicide hepatosplenomegaly, rheumatalgia, traumatic injury.
Herba Bidentis Tripartitae is Compositae annual herb.Classification system is Bidens tripartita L, and stem is upright, high 30 ~ 80 centimetres, sometimes can reach 90 centimetres; By base portion branch, without hair.Leaf is to life, and the leaf at stem top is little, does not sometimes divide, in stem, the blade pinnation of bottom or drastic crack; Sliver 3 ~ 5, ovum shape lanceolar is to narrow lanceolar; Rare closely avette, base portion wedge shape, rare subcircular, tip point or gradually point, raw irregular large sawtooth is dredged at edge, and top sliver is usually large than below person; Petiole has the wing.Head inflorescence top is raw, spherical or oblate spheroid; Phyllary 2 arranges, interior row lanceolar, dry film matter, isometric or slightly short with head inflorescence, outer row lanceolar or the lanceolar that falls, longer than head inflorescence, lobate; Flower is all tubulose, yellow; Stigma 2 splits, heat-clearing and toxic substances removing, yin nourishing arresting sweating.For flu, tonsillitis, pharyngolaryngitis, enteritis, dysentery, hepatitis, urinary system infection, pulmonary tuberculosis night sweat, amenorrhea; Furuncle and phyma is controlled in external, eczema, tinea.
Fine hair Cortex schefflerae octophyllae is Araliaceae Schettlera delavayi Agalma delavayi (Franch.) Hutch., is used as medicine with root or stem.The whole year can adopt, and section is dried.Dispelling, collateral-activating, invigorating the liver and kidney, bone and muscle strengthening.For fracture, bruise, lumbar muscle strain, rheumatic arthritis, lumbago due to renal deficiency, traumatic injury convalescent period.
Wheeling chrysanthemum is that Compositae Inulaplants shows arteries and veins Flos Inulae Inula nervosa Wall., is used as medicine with root.Autumn excavates, and cleans, dries.Expelling wind and removing dampness, activating collaterals to relieve pain, invigorating the stomach and promoting digestion.For rheumatalgia, soreness of the waist and knees, inappetence, stomachache.
Flos Eragrostinis cilianensis is the herb of grass family Eragrostis plant eragrostis cilianensisLink, Herba Eragrostidis pilosae and Herba Eragrostidis Poaeoidis, and Latin is called Puccinellia tenuiflora (Griseb.) Scribn., and the autumn in herb summer gathers, and inflorescence was adopted at the florescence, cleans cutting, dries.Wind and heat dispersing, diuresis.For vesical calculus, renal calculus, nephritis, pyelonephritis, cystitis, conjunctivitis, keratitis.Inflorescence: removing toxic substances, antipruritic.
Radix Cynanchi Auriculati is the tuber of dicotyledon medicine asclepiadaceae plant Cynanchum bungei Decne, and control prolonged illness weakness, chronic migratory arthralgia, soreness of the waist and knees, anemia, enterorrhagia, early whitening of beard and hair, neurasthenia, deficiency of YIN chronic malaria, ulcer does not close up for a long time, old people constipation.
Herba Melicae Scabrosae, Latin literary fame Pogonatherum crinitum (Thunb.) Kunth. Herba Melicae Scabrosae belongs to, grass family, Monocotyledonae, Angiospermae.River bank, crack in the wall, hillside and the country fair of moist field are being born in growth.: heat clearing away, expelling summer-heat, diuresis.For high heat of catching a cold, heatstroke, urinary tract infection, oedema due to nephritis, icterohepatitis, diabetes, children's's heat of a specified duration is not moved back.
Suffrutescent Securinega Twig, Latin is called Flueggea suffruticosa (Pall.) Baill., is the defoliation bush plant under Euphorbiaceae.China originates in plants, and there is wild distribution North China, and also there is growth northeast, Central China, East China, southwest, the Northwest.Expelling wind and activating blood circulation, the strong muscle of the kidney invigorating.For facial paralysis, poliomyelitis sequela, dizzy, deaf, neurasthenia, lethargy, sexual impotence.
Herba Boenninghauseniae is the herb of Rutaceae pine wind grass platymiscium Herba Boenninghauseniae Boenninghausenia sessilicarpa Levl..Autumn extracts herb, and clean cutting is dried.Heat-clearing and toxic substances removing, promoting blood circulation and stopping pain.For flu, tonsillitis, parotitis, bronchitis, stomachache abdominal distention, thromboangiitis obliterans, lumbago, traumatic injury.
DAWANHUA, Latin is called Calystegia hederacea Wall), be convolvulaceous plant.Herbaceos perennial: root stock: invigorating the spleen and benefiting QI, diuresis, regulating menstruation, leukorrhagia stopping; For insufficiency of the spleen dyspepsia, menoxenia, leucorrhea, milk is rare.Flower: pain relieving; Toothache is controlled in external.
Beneficial effect: the medicine that the present invention obtains can safe and effective treatment verruca plana.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1. specific embodiment 1: take Pseudostreblus indica Bur. 16g, numb sheep rattan 12g, row's money tree 14g, Herba Bidentis Tripartitae 15g, fine hair Cortex schefflerae octophyllae 16g, Wheeling chrysanthemum 10g, Flos Eragrostinis cilianensis 16g, Radix Cynanchi Auriculati 14g, Herba Melicae Scabrosae 12g, Suffrutescent Securinega Twig 16g, Herba Boenninghauseniae 12g, DAWANHUA 14g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, add adjuvant, be prepared into ointment according to a conventional method, the ointment of adult normal's 1 day consumption must be met.Be used for the treatment of verruca plana.External application, twice external sooner or later of every bu.
2. the present invention is to the clinical research of verruca plana
2.1 physical data: inventor collects the out-patient of 50 routine verruca plana altogether between in June ,-2012 in March, 2011, age 18-25 year, the course of disease 1-4 week.Be divided at random: treatment group 30 example, blank group 20 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2.2 verruca plana diagnostic criterias:
2.2.1 suddenly occur that the grain of rice arrives greatly the pimple of the large flat protuberance of Semen Glycines, smooth surface matter is hard, light brown or normal suitcase circle, oval or polygon, and number is more, most intensive, occasionally can be into strips arranged evenly along scratch.
2.2.2 be apt to occur in the places such as face, the back of the hand and forearm, multipair title occurs.General no conscious sympton, occasionally has micro-itching.
2.2.3 erythra is the flat pimple that foxtail millet grain is large, rounded, oval or polygon, and boundary is clear, smooth surface, and in filbert, brown or normal color of the leather, infringement is dispersed in or intensive, also can merge, can self inoculation because scratch, and the arrangement in beading.
2.2.4 no conscious sympton, or have slight gargalesthesia.
2.2.5 teenager is more common in.
2.2.6 the obvious hyperkeratosis of histopathological examination system and acanthosis, but different from verruca vulgaris, and without papillomatous hyperplasia, trochanterellus is mild prolonged only, without parakeratosis.Epidermis top cell has than verruca vulgaris cavity formation widely, and the core of Empity veside cell is positioned at cell central authorities, has different pyknosis.Wherein one deck core is dark basophilia, granular layer uniform thickened, and corneocyte is obvious basket shape because cavity is formed.Containing a large amount of melanocytes in some verruca plana basal layer, intradermal is without special change.
2.3 test method
2.3.1 treatment group external the present invention is according to the obtained ointment of specific embodiment 1, sooner or later each once.15 days courses for the treatment of.
2.3.2 blank group external placebo ointment, sooner or later respectively once.15 days courses for the treatment of.
2.4 criterions of therapeutical effect and therapeutic outcome
2.4.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and test chamber inspection is normal.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, lab testing improvement or normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
2.4.2 statistical result is treated in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) |
| Treatment group | 30 | 15 | 10 | 5 | 83.3 |
| Blank group | 20 | 2 | 3 | 15 | 25 |
Visible, the medicine that the present invention obtains can safe and effective treatment verruca plana.
Claims (2)
1. treat the ointment of verruca plana for one kind, it is characterized in that, it is prepared by the raw material of following parts by weight: Pseudostreblus indica Bur. 16 parts, 12 parts, numb sheep rattan, row money set 14 parts, Herba Bidentis Tripartitae 15 parts, fine hair Cortex schefflerae octophyllae 16 parts, Wheeling chrysanthemum 10 parts, Flos Eragrostinis cilianensis 16 parts, Radix Cynanchi Auriculati 14 parts, Herba Melicae Scabrosae 12 parts, Suffrutescent Securinega Twig 16 parts, Herba Boenninghauseniae 12 parts, DAWANHUA 14 parts.
2. treat the application of ointment in treatment verruca plana medicine of verruca plana as claimed in claim 1.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104800353A (en) * | 2015-05-02 | 2015-07-29 | 臧孝国 | Traditional Chinese medicine composition for treating hepatitis B |
| CN104840500A (en) * | 2015-06-01 | 2015-08-19 | 徐艳 | Gel for treating flat warts as well as preparation method and application thereof |
| CN115501307A (en) * | 2022-11-04 | 2022-12-23 | 潘夫 | Traditional Chinese medicine composition for treating HPV infection and traditional Chinese medicine preparation and application thereof |
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| CN102698133A (en) * | 2012-05-02 | 2012-10-03 | 王建中 | Traditional Chinese medicine composition for treating verruca plana |
| CN102836357A (en) * | 2011-06-22 | 2012-12-26 | 惠振明 | Traditional Chinese medicine preparations used for treating flat warts |
| CN103751629A (en) * | 2013-11-26 | 2014-04-30 | 郭文喜 | Traditional Chinese medicine composition for treating verruca plana through external washing |
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| CN102302638A (en) * | 2011-08-13 | 2012-01-04 | 李为国 | Traditional Chinese medicine (TCM) formula for treating flat wart |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104800353A (en) * | 2015-05-02 | 2015-07-29 | 臧孝国 | Traditional Chinese medicine composition for treating hepatitis B |
| CN104840500A (en) * | 2015-06-01 | 2015-08-19 | 徐艳 | Gel for treating flat warts as well as preparation method and application thereof |
| CN115501307A (en) * | 2022-11-04 | 2022-12-23 | 潘夫 | Traditional Chinese medicine composition for treating HPV infection and traditional Chinese medicine preparation and application thereof |
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Application publication date: 20150121 |