CN104273179A

CN104273179A - Preparation method of oxymatrine aqueous solution

Info

Publication number: CN104273179A
Application number: CN201310289090.6A
Authority: CN
Inventors: 于广威
Original assignee: QINGDAO RUSSELL BIOTECHNOLOGY CO Ltd
Current assignee: QINGDAO RUSSELL BIOTECHNOLOGY CO Ltd
Priority date: 2013-07-11
Filing date: 2013-07-11
Publication date: 2015-01-14

Abstract

The invention discloses an oxymatrine aqueous solution plant bactericide and a preparation method thereof and aims to provide a plant bactericide which takes Chinese herbal medicines as raw materials, has no harm on people and animals, is low in toxin and low in cost, is super-efficient and has high content of oxymatrine, and a preparation method of the plant bactericide. The plant bactericide belongs to a plant insecticide, contains super high content, about 2.4%, of oxymatrine, takes contact killing as a main manner and suffocation as an auxiliary manner and has good effects on killing aphids, whiteflies, red spiders and the like. The oxymatrine aqueous solution plant bactericide has the characteristics of high decomposition speed, high efficiency, low toxin, no residues, no pollution and the like, and is a safe type domestic or flower-cultivation insecticide.

Description

A kind of preparation method of oxymatrine aqua

Technical field

The invention belongs to field of biological pesticide, in particular, is a kind of plant extraction liquid insecticide being main component with matrine vegetable extract, and has the preparation method of aqua.

Background technology

China is a typical large agricultural country.Always rural economy, rural development and rural demography are one of the important policies of China.For a long time, because using chemical pesticide in a large number, cause vast rural area farm produce production base to produce the serious three disasters, damage by disease and insect pesticide resistance constantly increases, and has buried hidden danger to the safety of agricultural product.In addition, the pollution of residue of pesticide to environment is outstanding day by day.Three disasters problem not only constrains the development of agricultural, and seriously jeopardize human life with healthy, the harm that it causes is immeasurable simultaneously.Government also takes certain measure to this: five kinds of high-toxic organic phosphorus agricultural chemicals such as acephatemet, parathion-methyl, parathion, nuvacron and thiamines were destroyed in 2007 by the Ministry of Agriculture, and stops using 288 pesticidal preparations to stop.As can be seen here, the attention degree of country to agricultural product production is very high.Use green, safety, non-harmful plant insecticide, must become important developing direction, have wide market development prospect, pollute for environmental protect, the safety increasing agricultural product all has epoch-making meaning.But when current bactericide uses on crops, consumption is large, and mu cost is high, and every mu of ground will use 250-500 gram, and labour pays height, is not that orientation is specially killed.

Summary of the invention

The present invention is to overcome weak point of the prior art, and providing a kind of is raw material with Chinese herbal medicine, and to person poultry harmless, low toxicity super-high-efficient, matrine content is high, the matrine agent plant pesticide that use cost is low.

Another object of the present invention is to provide a kind of preparation method of matrine agent plant pesticide.

The present invention is achieved through the following technical solutions: a kind of oxymatrine aqua, be by vegetable insecticide and auxiliary agent formulated, vegetable insecticide is made up of kuh-seng, the tuber of stemona, tobacco, China tree, Dalmatian chrysanthemum compatibility, and its compatibility is: kuh-seng 52.5-72kg, tuber of stemona 12-22.5kg, tobacco 22.5-37.5kg, China tree 15-37.5kg, Dalmatian chrysanthemum 4.5-15kg.

In above-mentioned oxymatrine, add thunder godvine, addition is thunder godvine 7.5-15kg.

1. get kuh-seng, tobacco, China tree, Dalmatian chrysanthemum, thunder godvine, pepper, respectively pulverization process, for subsequent use after crossing 20-80 mesh sieve.

2. get above-mentioned various raw material by charge ratio to be respectively charged in stainless steel batch extractor, add crude drug 6-8 times water gaging, soak 4-8 hour at normal temperatures, less than 95 DEG C, secondary is extracted in boiling, carries 4-8 hour at every turn, and secondary raffinate merges, filtration, and it is for subsequent use to collect gained filtrate.

3. each for gained filtrate is inputted in Three-effect concentration device respectively, be decompressed to 0.5-0.1MPa, at 70-95 DEG C of temperature, be concentrated to 1ml be equivalent to crude drug 3-5g, be i.e. 22-28Be, measure content and collect concentrate, obtain extract.The active constituent content of various Chinese medicine: kuh-seng 1-2.5%, tobacco 1-9%, China tree 0.22-0.32%, Dalmatian chrysanthemum 1-1.5%, thunder godvine 0.45-0.6%.

4. each for gained concentrate is got kuh-seng 15-22.5kg respectively, thunder godvine 2-6kg, be input in reactor, 70% ethanolic solution is added in 3-4:1 ratio, stir 20-60 minute, put into settling tank precipitation 10-48 hour, elimination insoluble matter, detect matrine to standard content, by in gained filtrate input destilling tower, be heated to 85-95 DEG C of distillation, reclaim ethanol to 1 of original volume, 3-1, 2, collect mother liquor to be input to again in reactor, the ethanol 17.5-24kg that concentration is 75-90% is added successively by required charge ratio, preservative 0.3-1.3kg, bleeding agent 2.5-6kg, by above-mentioned various auxiliary agent mixing 1.5-3h, obtain 2.4% matrine water agriculture chemicals, main detection composition matrine content 2.4%.

This product belongs to vegetable insecticide, containing have an appointment 2.4% very high content matrine, mainly to tag, it is auxiliary for fumigating, and by epidermal penetration to skin inner layer, reaches nervous centralis through nerve ending, block nerves is conducted, and enzyme acetylcholine is piled up, and makes insect produce excited Poisoning choke dead.Good effect is had to killing aphid, aleyrodid class, two spotted spider mite etc.Have decomposition rate fast, efficient, low toxicity, noresidue, the feature such as pollution-free are a kind of safety type home-use, flower gardening insecticide.

Kuh-seng ( sophoraflavesensait), belong to leguminous plant.The matrine with insecticidal action extracted from radix sophorae and the structural formula of oxymatrine as follows:

Chemical formula is: C ₁₅h ₂₄n ₂o, C ₁₅h ₂₄n ₂o ₂, relative molecular mass is respectively: 248.36, and 264.36.

Oxymatrine aqua has following pluses and minuses:

1, there is efficient, broad spectrum activity

Oxymatrine aqua, to Lepidoptera, the Semiptera of vegetables, fruit tree, flowers, forest, field crop, sticks up the various pests such as wing order, Homoptera, diptera and board wax order and has and significantly kill and preventive effect.

2, there is hypotoxicity

The general toxicity ratio of chemical pesticide is comparatively large, while kill pests, also works the mischief to the life security of people and animals.And 2.4% aqueous matrine solution, be that pure natural plant is made, effectively avoid the threat of chemical pesticide composition to people and animals, belong to a kind of safe agricultural chemicals.2.4% aqueous matrine solution, through field trial repeatedly, has the effect of excellent pest control, and does not find people and animals' intoxicating phenomenon, is the desirable regeneration product of existing agricultural chemicals.

3, non-environmental-pollution problem

(1) noresidue

The problem that in the use procedure of chemical pesticide, existence one is very serious is exactly the longevity of residure, the longevity of residure of some agricultural chemicals is long especially, even residual serious in people's carcass, agricultural chemicals is caused to accumulate, endanger healthy, the harm of agricultural chemicals has become a global problem, and the highly toxic pesticide hexachlorcyclohexane forbidding to use even also can be detected in the South Pole, the harm of visible chemical pesticide is big.And 2.4% aqueous matrine solution utilizes multiple pure natural plant through a kind of low-toxicity product of scientific technology process, there is not residue problem through overtesting, any danger side of body is not formed to ecotopes such as people and animals yet.

(2) produce without the three wastes

Three industrial wastes are serious problems urgently to be resolved hurrily that current environment pollutes, government consumes a large amount of manpowers for this reason, financial resources and material resources also fundamentally do not reverse this passive situation, agriculture chemical factory is a large amount of producers of the three wastes, therefore the production of agriculture chemical is replaced with 2.4% aqueous matrine solution, then effectively can solve the problem of the three wastes, there is following reason: useless the making remained by 1. producing can be used for fermenting, the biogas produced that ferments can be used as the good energy of one, remaining send out medicine liquor-saturated and make through with other fertilizer by a certain percentage proportioning after, make ginseng fertilizer, the first-class fertilizer such as grape is fertile, there are good development prospect and wide market, 2. the industrial water after using, can recycling again after simple process, can also as medicine water for shower, and the health for human body makes due contribution.3. without the generation of waste gas.

(3) raw material sources are extensive, cheap

These raw materials such as kuh-seng, tobacco, trifoliate jewelvine, thunder godvine, Dalmatian chrysanthemum are all easy to get, particularly radix sophorae in China northeast, there is growth the mountain area of North China most area and hilly country, spring, Qiu Erji can excavate.

(4) extract and preparation process easy, be easy to formation large-scale production

The production technology of oxymatrine aqua is simple, and equipment needed thereby is less, and production procedure cylinder is bright, clear.Its technological process is: raw material one clean ~ pulverize an extraction ~ concentrated and moan and liquor-saturatedly heavyly heat up in a steamer ~ mix one for one time and may fill ~ put in storage, and this just considerably increases the feasibility of large-scale production and exploitation.In fact this technique belongs to conventional herb liquid extraction process.

Embodiment one

Manufacture oxymatrine aqua, by kuh-seng, bitter chaff, tobacco, trifoliate jewelvine, thunder godvine, maple willow, hop, rule grass, mountain flower green pepper, through cleaning, pulverize, extraction, concentrated, alcohol precipitation, return and heat up in a steamer, be mixed, its kuh-seng, bitter kerria, tobacco, trifoliate jewelvine, thunder godvine, maple grab that grass do not restrained by golden hop, the compatibility of mountain flower green pepper is: kuh-seng 20%, bitter strain 20%, tobacco 10%, trifoliate jewelvine 5%, thunder godvine 5%, maple willow 20%, hop 6%, rule grass 4%, mountain flower green pepper 10%.

Its process is:

1, get kuh-seng, bitter strain, tobacco, trifoliate jewelvine, thunder godvine, maple willow, hop, rule grass, mountain flower green pepper by above-mentioned compatibility respectively, and wash respectively, after drying and crushing, sieve by 20-80 mesh sieve;

2, respectively with the imitative extraction of atmosphere, reduce with water, carry out again concentrating, liquor-saturated heavy (adopt second liquor-saturated), return and stay, finally extract is mixed, makes extract comprise matrine 2.4%, nicotine 0.3%, bitter kerria's alkali 0.6%, wilfordine 0.4%, rotenone 0.1%.This agricultural chemicals all has obvious control efficiency to the Lepidoptera of vegetables, fruit tree, flowers, forest, field crop, Semiptera, Homoptera, the various pests such as diptera and board end order.

Embodiment two

The third material combination manufacturing oxymatrine aqua is: kuh-seng 6%, bitter chaff 30%, tobacco 10%, trifoliate jewelvine 6%, thunder godvine 20%, maple willow 4%, hop 10%, rule grass 6%, mountain flower green pepper 10%.This agricultural chemicals has special efficacy to insect.The production technology of embodiment two is identical with embodiment one.

Claims

1. an oxymatrine aqua, is characterized in that, containing the Chinese medicine extract 25% of matrine in insecticide, inorganic elements 1.5%, plant fat 5%, sugar 5%, water 60.5%, wherein containing have an appointment 2.4% very high content matrine.

2. a preparation method for a kind of oxymatrine aqua according to claim 1, is characterized in that: first washed by all Chinese medicine, cuts into slices or grind, sieving, then extracting, concentrated, finally compositely obtains described aqueous matrine solution product.

3. the technique of matrine insecticide according to claim 3, is characterized in that: in leaching process, drops in batch extractor by the Chinese medicine material handled well, through 105 DEG C of boilings until weight is constant, carry 4-8 hour, secondary raffinate merges at every turn, filter, it is for subsequent use to collect gained filtrate.

4. the Pesticidal matrine solution production technology according to claim 3,4, it is characterized in that: each for gained filtrate is inputted in Three-effect concentration device respectively, be decompressed to 0.5-0.1MPa, at 70-95 DEG C of temperature, be concentrated to 1ml be equivalent to crude drug 3-5g, i.e. 22-28Be, measure content and collect concentrate, obtain extract.

5. the active constituent content of various Chinese medicine: kuh-seng 2.5-3.6%, tobacco 1-9%, China tree 0.22-0.32%, Dalmatian chrysanthemum 1-1.5%, thunder godvine 0.45-0.6%.

6. the Pesticidal matrine solution production technology according to claim 3,4, it is characterized in that: time composite, ethanol 17.5-24kg that concentration is 75-90%, preservative 0.3-1.3kg, bleeding agent 2.5-6kg is added successively by required charge ratio, by above-mentioned various auxiliary agent mixing 1.5-3h, obtain 2.4% aqueous matrine solution agricultural chemicals, the main composition matrine content that detects can reach 2.4%.

7. in auxiliary agent, the optional sorbic acid of preservative, Sodium Benzoate etc., the optional dimethyl sulfoxide (DMSO) of bleeding agent etc.