CN104257835B - 一种治疗妊娠皮肤瘙痒症的中药外洗剂 - Google Patents

一种治疗妊娠皮肤瘙痒症的中药外洗剂 Download PDF

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CN104257835B
CN104257835B CN201410512969.7A CN201410512969A CN104257835B CN 104257835 B CN104257835 B CN 104257835B CN 201410512969 A CN201410512969 A CN 201410512969A CN 104257835 B CN104257835 B CN 104257835B
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高冠彩
徐蒙
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/76Salicaceae (Willow family), e.g. poplar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions

Abstract

本发明公开了一种治疗妊娠皮肤瘙痒症风热血燥证的中药外洗剂。中医辨证治疗该症以疏风清热止痒为主,为此,本发明选择中药一枝黄花、牛蒡根、金盏银盘、旱芹、满天星、硬水黄连、旱柳叶、对叶豆、鹿梨根皮、野薴麻,制成外洗剂,经临床试验,总有效率96.7%,效果显著。在整个治疗过程中,患者未出现明显的不良反应,血、尿、大便常规、心电图及肝、肾功能均无明显变化。

Description

一种治疗妊娠皮肤瘙痒症的中药外洗剂
技术领域
[0001 ]本发明涉及一种中药组合物,尤其涉及一种治疗妊娠皮肤瘙痒症风热血燥证的中药外洗剂。
背景技术
[0002]妊娠皮肤瘙痒症大多发生在妇女怀孕的中后期,患病后孕妇常常突然觉得全身皮肤发痒并有蚂蚁在皮肤上爬行和烧灼不适的感觉,皮肤上出现一块块的红斑或风疹块,尤其是夜间常因剧烈的皮肤瘙痒而难以入睡,除了影响孕妇的健康外,对胎儿的发育也有一定的影响,所以及时诊治本病对保障母婴健康均有一定意义。西医治疗本病认为在妊娠中晚期可口服朴尔敏、敏迪、赛庚暖等抗组织胺药,但在妊娠头3个月尽量不要用此类药物,以免影响胎儿正常发育或引起致畸现象发生。
[0003]申请人经过多年的临床实践证明,利用中药外洗治疗此病,不但疗效较好,而且还可以防止瘙痒抓破后的感染,有益于皮损修复,副作用小,对母体及胎儿影响小。
发明内容
[0004]本发明的目的是提供一种治疗妊娠皮肤瘙痒症的中药外洗剂。辨证治疗该症应以疏风清热止痒为原则。
[0005]本发明的目的是通过以下技术方案实现的,该治疗妊娠皮肤瘙痒症的中药外洗剂由以下重量份的中药制成:一枝黄花8-10份、牛蒡根10-20份、金盏银盘30-40份、旱芹9-15份、满天星8-12份、硬水黄连3-9份、旱柳叶8-10份、对叶豆3-6份、鹿梨根皮10-15份、野寧麻15-25 份。
[0006]优选的,一枝黄花9份、牛蒡根15份、金盏银盘35份、旱芹12份、满天星10份、硬水黄连6份、旱柳叶9份、对叶豆5份、鹿梨根皮12份、野寧麻20份。
[0007]制备方法水煎取药液备用。
[0008]方中:一枝黄花疏风清热、消肿解毒;牛蒡根祛风热、消肿毒;金盏银盘疏风清热、解毒散瘀;旱芹清热平肝、祛风利湿;满天星祛风清热;硬水黄连清湿热、解毒;旱柳叶散风,祛湿,清湿热;对叶豆杀虫止痒;鹿梨根皮解毒止痒;野寧麻清热解毒、祛风止痒、镇静。
[0009] 临床资料
[0010] 1、一般资料本研究3O例病例均为本院产科门诊就诊患者,年龄26〜35岁,平均29.1岁。其中处于妊娠早期患者3例,妊娠中期患者18例,妊娠晚期患者9例。病程3d〜30d,平均13d。
[0011] 2、妊娠皮肤瘙痒症风热血燥证型诊断标准:皮肤干燥,瘙痒不堪,抓破后皮损出血,继则痛痒,或感风热后加剧,口干喜饮,小便短黄,大便干结,舌红苔黄,脉浮数。
[0012] 3、治疗及护理方法患者使用本发明所述中药外洗剂,称取一枝黄花9g、牛蒡根15g、金盏银盘35g、旱芹12g、满天星10g、硬水黄连6g、旱柳叶9g、对叶豆5g、鹿梨根皮12g、野寧麻20g,水煎取药液备用,每日洗浴时,加入药液30〜50毫升于浴水中洗浴,连用7天为一疗程,连续治疗2个疗程。护理上应注意,孕妇首先要减轻精神负担,避免烦躁和焦虑不安;避免搔抓止痒;勤换内衣内裤;洗澡时切忌用温度过高的水或使用碱性肥皂使劲擦洗,因为这样会加重瘙痒;防止食物因素的刺激,如少吃辣椒、生姜、生蒜等刺激性的食物。海鲜的摄入要适量,因为海鲜能加重皮肤瘙痒;穿纯棉的衣物,避免化纤织物与皮肤发生摩擦。
[0013] 4、疗效标准显效:瘙痒基本消失,继发皮损明显改善;有效:瘙痒减轻,继发皮损有所改善;无效:瘙痒和继发皮损均无改善。
[0014] 5、治疗结果30例患者,其中显效15例(50% ),有效14例(46.7% ),无效I例(3.3%),总有效率96.7%,效果显著。在整个治疗过程中,患者未出现明显的不良反应,血、尿、大便常规、心电图及肝、肾功能均无明显变化。
[0015] 6、典型病例周某,女,29岁,2014年I月28日初诊。妊娠23周,全身出现瘙痒已经半月,以躯体、四肢为主,皮肤干燥,瘙痒难受,时隐时现。口干喜饮,小便短黄,大便干结,舌红苔黄,脉浮数。治法疏风清热止痒。方用:一枝黄花9g、牛蒡根15g、金盏银盘35g、旱芹12g、满天星10g、硬水黄连6g、旱柳叶9g、对叶豆5g、鹿梨根皮12g、野寧麻20g。水煎取药液备用。每日洗浴时,加入药液30〜50毫升于浴水中洗浴,连用7天为一疗程,连续治疗2个疗程;2月20日二诊:瘙痒得到很大程度缓解,口淡,多唾,舌脉如上。继续使用上方7d;2月28日三诊:瘙痒消失,随访2个月未再复发。
具体实施方式
[0016]实施例一:称取一枝黄花9g、牛蒡根15g、金盏银盘35g、旱芹12g、满天星10g、硬水黄连6g、旱柳叶9g、对叶豆5g、鹿梨根皮12g、野寧麻20g,水煎取药液备用。
[0017]实施例二:称取一枝黄花10g、牛蒡根10g、金盏银盘40g、旱芹9g、满天星12g、硬水黄连3g、旱柳叶I Og、对叶豆3g、鹿梨根皮15g、野寧麻25g,水煎取药液备用。
[0018]实施例三:称取一枝黄花8g、牛蒡根20g、金盏银盘30g、旱芹15g、满天星8g、硬水黄连9g、旱柳叶8g、对叶豆6g、鹿梨根皮I Og、野寧麻15g,水煎取药液备用。

Claims (2)

1.一种治疗妊娠皮肤瘙痒症的中药外洗剂,其特征在于该中药外洗剂由以下重量份的中药制成:一枝黄花8-10份、牛蒡根10-20份、金盏银盘30-40份、旱芹9-15份、满天星8-12份、硬水黄连3-9份、旱柳叶8-10份、对叶豆3-6份、鹿梨根皮10-15份、野寧麻15-25份。
2.如权利要求1所述的一种治疗妊娠皮肤瘙痒症的中药外洗剂,其特征在于该中药外洗剂由以下重量份的中药制成:一枝黄花9份、牛蒡根15份、金盏银盘35份、旱芹12份、满天星10份、硬水黄连6份、旱柳叶9份、对叶豆5份、鹿梨根皮12份、野寧麻20份。
CN201410512969.7A 2014-09-19 2014-09-19 一种治疗妊娠皮肤瘙痒症的中药外洗剂 Expired - Fee Related CN104257835B (zh)

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CN103550420A (zh) * 2013-09-24 2014-02-05 王兵 一种治疗荨麻疹的中药
CN103893495A (zh) * 2014-04-20 2014-07-02 孙艳萍 一种治疗皮肤瘙痒的中药药水及制备方法
CN103961463A (zh) * 2013-01-30 2014-08-06 陕西兴邦药业有限公司 一种治疗皮肤瘙痒病、荨麻疹的中药组合物及其制备方法

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