CN104244826A - 用于监测生物统计指标的组合物和方法 - Google Patents

用于监测生物统计指标的组合物和方法 Download PDF

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Publication number
CN104244826A
CN104244826A CN201380019079.6A CN201380019079A CN104244826A CN 104244826 A CN104244826 A CN 104244826A CN 201380019079 A CN201380019079 A CN 201380019079A CN 104244826 A CN104244826 A CN 104244826A
Authority
CN
China
Prior art keywords
injection
fluorescent label
hematocrit
fluorescent
calibration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201380019079.6A
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English (en)
Chinese (zh)
Inventor
丹尼尔·迈尔
布鲁斯·莫利托里斯
埃林·谢里登
鲁本·桑多瓦尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacophotonics Inc
Original Assignee
Pharmacophotonics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacophotonics Inc filed Critical Pharmacophotonics Inc
Priority to CN201810162169.5A priority Critical patent/CN108261183A/zh
Publication of CN104244826A publication Critical patent/CN104244826A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0088—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for oral or dental tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14535—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring haematocrit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/20—Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
    • A61B5/201—Assessing renal or kidney functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6814—Head
    • A61B5/682—Mouth, e.g., oral cavity; tongue; Lips; Teeth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Optics & Photonics (AREA)
  • Urology & Nephrology (AREA)
  • Audiology, Speech & Language Pathology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Physiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201380019079.6A 2012-02-17 2013-02-15 用于监测生物统计指标的组合物和方法 Pending CN104244826A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810162169.5A CN108261183A (zh) 2012-02-17 2013-02-15 用于监测生物统计指标的组合物和方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261600182P 2012-02-17 2012-02-17
US61/600,182 2012-02-17
PCT/US2013/026277 WO2013123285A1 (en) 2012-02-17 2013-02-15 Compositions and methods for monitoring biometric indicators

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201810162169.5A Division CN108261183A (zh) 2012-02-17 2013-02-15 用于监测生物统计指标的组合物和方法

Publications (1)

Publication Number Publication Date
CN104244826A true CN104244826A (zh) 2014-12-24

Family

ID=48984726

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201380019079.6A Pending CN104244826A (zh) 2012-02-17 2013-02-15 用于监测生物统计指标的组合物和方法
CN201810162169.5A Pending CN108261183A (zh) 2012-02-17 2013-02-15 用于监测生物统计指标的组合物和方法

Family Applications After (1)

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CN201810162169.5A Pending CN108261183A (zh) 2012-02-17 2013-02-15 用于监测生物统计指标的组合物和方法

Country Status (8)

Country Link
US (2) US20140369936A1 (https=)
EP (2) EP2814393B1 (https=)
JP (3) JP2015510436A (https=)
CN (2) CN104244826A (https=)
AU (1) AU2013221451A1 (https=)
CA (1) CA2863788A1 (https=)
IN (1) IN2014DN06772A (https=)
WO (1) WO2013123285A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111902075A (zh) * 2018-01-16 2020-11-06 梅约医学教育与研究基金会 快速评估肾功能的系统和方法
CN112384130A (zh) * 2018-06-28 2021-02-19 贝克顿·迪金森公司 用于标准化血液培养测量系统中的信号的系统和方法
CN112567227A (zh) * 2018-06-08 2021-03-26 珀金埃尔默健康科学股份有限公司 多光谱分析系统的校准

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AU2013221451A1 (en) * 2012-02-17 2014-08-21 Pharmacophotonics, Inc. Compositions and methods for monitoring biometric indicators
US10082465B2 (en) 2013-10-24 2018-09-25 Pharmacophotonics, Inc. Compositions comprising a buffering solution and an anionic surfactant and methods for optimizing the detection of fluorescent signals from biomarkers
US20180180622A1 (en) * 2015-06-24 2018-06-28 Pharmacophotonics, Inc. D/B/A Fast Biomedical Method and apparatus for determining biometric indicators using multiple fluorescent markers
CA3051963A1 (en) * 2017-01-30 2018-08-02 Medibeacon Inc. Method for non-invasive monitoring of fluorescent tracer agent with diffuse reflection corrections
US20200174018A1 (en) * 2018-10-05 2020-06-04 Pharmacophotonics, Inc. D/B/A Fast Biomedical Method and apparatus for determining interstitial volume
EP3990894A1 (en) * 2019-06-28 2022-05-04 ProciseDx Inc. Methods for accommodating for sample matrix effects in light measurement assays
CN116138797A (zh) * 2022-10-24 2023-05-23 中国人民解放军陆军军医大学第二附属医院 基于SPECT/CT的99mTc的衰减系数测定方法、GFR值计算方法及系统

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US20030017111A1 (en) * 2000-07-19 2003-01-23 Carlos Rabito Fluorescent agents for real-time measurement of organ function
US20050283058A1 (en) * 2004-06-09 2005-12-22 Choo-Smith Lin-P Ing Detection and monitoring of changes in mineralized tissues or calcified deposits by optical coherence tomography and Raman spectroscopy
CN101208109A (zh) * 2005-04-19 2008-06-25 印第安纳大学研究及科技有限公司 肾功能分析方法和仪器
WO2010127136A2 (en) * 2009-04-30 2010-11-04 Pharmacophotonics, Inc. Measurement of body fluid volumes
US20110201940A1 (en) * 2008-04-18 2011-08-18 Exing Wang Renal Function Analysis Method and Apparatus
US20110318712A1 (en) * 2010-06-29 2011-12-29 Reddy Megha Method for cleaning the oral cavity

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US20060178556A1 (en) * 2001-06-29 2006-08-10 Intuitive Surgical, Inc. Articulate and swapable endoscope for a surgical robot
US7264148B2 (en) * 2001-09-12 2007-09-04 Terumo Kabushiki Kaisha Drug container and drug infusion device comprising the same
EP1620002B1 (en) * 2003-04-24 2012-01-04 The Board Of Regents, The University Of Texas System Noninvasive blood analysis by optical probing of the veins under the tongue
DE102004024494B4 (de) * 2004-05-16 2019-10-17 Dürr Dental SE Medizinische Kamera
US7440788B2 (en) * 2004-08-26 2008-10-21 Kelvyn Enterprises, Inc. Oral health measurement clamping probe, system, and method
US7386333B1 (en) * 2005-04-29 2008-06-10 Henryk Birecki Test subject monitoring device
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WO2009061769A1 (en) * 2007-11-06 2009-05-14 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern Califorina Measurement of hematocrit and cardiac output from optical transmission and reflection changes
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JP2011521899A (ja) * 2008-04-18 2011-07-28 ファーマコフォトニクス，インコーポレイティド 腎機能の分析方法及び装置
JP2011528275A (ja) * 2008-07-17 2011-11-17 ミセル テクノロジーズ，インク． 薬物送達医療デバイス
GB201011913D0 (en) * 2010-07-15 2010-09-01 Lux Innovate Ltd Detecting device
AU2013221451A1 (en) * 2012-02-17 2014-08-21 Pharmacophotonics, Inc. Compositions and methods for monitoring biometric indicators

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CN1309545A (zh) * 1998-05-16 2001-08-22 赫尔穆特·亨德股份有限公司 用于牙菌斑检测的带有荧光装置的牙刷
US20030017111A1 (en) * 2000-07-19 2003-01-23 Carlos Rabito Fluorescent agents for real-time measurement of organ function
US20050283058A1 (en) * 2004-06-09 2005-12-22 Choo-Smith Lin-P Ing Detection and monitoring of changes in mineralized tissues or calcified deposits by optical coherence tomography and Raman spectroscopy
CN101208109A (zh) * 2005-04-19 2008-06-25 印第安纳大学研究及科技有限公司 肾功能分析方法和仪器
US20110201940A1 (en) * 2008-04-18 2011-08-18 Exing Wang Renal Function Analysis Method and Apparatus
WO2010127136A2 (en) * 2009-04-30 2010-11-04 Pharmacophotonics, Inc. Measurement of body fluid volumes
US20110318712A1 (en) * 2010-06-29 2011-12-29 Reddy Megha Method for cleaning the oral cavity

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111902075A (zh) * 2018-01-16 2020-11-06 梅约医学教育与研究基金会 快速评估肾功能的系统和方法
CN112567227A (zh) * 2018-06-08 2021-03-26 珀金埃尔默健康科学股份有限公司 多光谱分析系统的校准
US11940381B2 (en) 2018-06-08 2024-03-26 Revvity Health Sciences, Inc. Calibration of multispectral analysis systems
CN112384130A (zh) * 2018-06-28 2021-02-19 贝克顿·迪金森公司 用于标准化血液培养测量系统中的信号的系统和方法

Also Published As

Publication number Publication date
US20180256755A9 (en) 2018-09-13
CA2863788A1 (en) 2013-08-22
IN2014DN06772A (https=) 2015-05-22
US20180147302A1 (en) 2018-05-31
JP2015510436A (ja) 2015-04-09
US20140369936A1 (en) 2014-12-18
EP2814393B1 (en) 2017-04-05
AU2013221451A1 (en) 2014-08-21
EP3207873A1 (en) 2017-08-23
EP2814393A4 (en) 2015-10-14
JP2020163170A (ja) 2020-10-08
WO2013123285A1 (en) 2013-08-22
JP2018102959A (ja) 2018-07-05
EP2814393A1 (en) 2014-12-24
CN108261183A (zh) 2018-07-10

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Application publication date: 20141224