CN104223304B - A kind of spirit can the product that menopause symptom be improved and preparation method thereof of releiving - Google Patents
A kind of spirit can the product that menopause symptom be improved and preparation method thereof of releiving Download PDFInfo
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- CN104223304B CN104223304B CN201410523314.XA CN201410523314A CN104223304B CN 104223304 B CN104223304 B CN 104223304B CN 201410523314 A CN201410523314 A CN 201410523314A CN 104223304 B CN104223304 B CN 104223304B
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/34—Tea substitutes, e.g. matè; Extracts or infusions thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/40—Shaping or working of foodstuffs characterised by the products free-flowing powder or instant powder, i.e. powder which is reconstituted rapidly when liquid is added
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of spirit can the product that menopause symptom be improved and preparation method thereof of releiving.Product of the present invention for primary raw material, prepares a kind of product that safely, have no side effect through scientific compatibility, practice test with the extract of the plants such as the root of kudzu vine, agate coffee, soybean and valerian.The product that the present invention relates to can releive spirit, regulate female incretion balance, improve the various symptoms of Menopause, for women's climacteric or " stealthy climacteric " provides a kind of pointed product, in women's functional product field, there are wide market prospects.
Description
Technical field
The present invention relates to a kind of functional product, particularly relate to the functional product that a kind of spirit of can releiving also can improve menopause symptom.
Background technology
General women entered into the climacteric period by 45 ~ 55 years old: health internal system function reduction, ovarian function fail gradually, female hormone falls sharply, vegetative nerve functional disturbance, have influence on prehypophyseal partial function, and then affect cerebral cortex and hypothalamic activity, lure that nervous function is unstable into, thus the irritability that reduction adaptive capacity to external world, increase intersection are neural.The change of physical function causes the psychology of climacteric women and the state of mind to change, and occurs anxiety, depression, neuroticism, the symptom such as emotional, causes inconvenience greatly and puzzlement to life.According to relevant research, the white collar women of some three teens is large due to operating pressure, also starts to have occurred dry skin, feels exhausted, the menopause symptoms such as irritated insomnia, vegetative nerve functional disturbance, is medically called " stealthy climacteric ".
Complementing estrogen series products and traditional Chinese medicine series products is mainly contained on the market at present for the product of climacteric metancholia, estrogen in body is increased to improve climacteric metancholia shape by the chemokine in product or plant hormone, but the simple estrogen that increases can have side effects, and can not solve involutional mental symptom.And have the women of about 75% to there will be the different Novel presentation of the order of severity climacteric according to statistics, main based on mental symptom, these symptoms are not just can be solved by complementing estrogen, and also do not have to releive spirit improve the product of menopause symptom in the market.
In the medicine relating generally to climacteric metancholia alleviation aspect or food, the root of kudzu vine, agate coffee, soybean, valerian and extract thereof are wherein important several.
The root of kudzu vine is the block root of pulse family Pueraria elegant jessamine, has removing toxic substances, brings down a fever, the effect promoted the production of body fluid to quench thirst.Containing abundant isoflavones and high-quality starch, it is the integration of drinking and medicinal herbs dual purpose plant of health ministry approval.Root of kudzu vine total isoflavone content is up to 7.6%, and kudzuvine root isoflavone has specific active function to ovary, can increase the blood of ovary local microcirculation system, nourishes ovary, activates naturally secreting of the sub-sex hormone of ovary, delaying female aging to a certain extent.
Agate coffee is a kind of new resource raw-food material, contains the carbohydrate and protein and multiple sterol and trace element that enrich.Also containing the active components of plants that two classes are new in agate coffee: macamide and agate coffee alkene, these two kinds of compositions are by acting on human hypothalamic-hypophysis-body of gland, can active balance human body hormone secretion, thus to alleviation climacteric metancholia, improvement function, enhancement for, improve sub-health state and have extraordinary effect.
Soybean contains rich in protein, fat, vitamin and mineral matter, also containing the physiological activator that isoflavones etc. is useful to health, isoflavones and estrogen contain similar structure, moisture of skin and elasticity situation can be improved, alleviate middle and aged women climacteric metancholia, improve osteoporosis symptoms.
Valerian has effect of tranquilizing and allaying excitement, antidepression, relieving spasm and pain, is clinically used for the treatment of confused and worried, palpitation and insomnia etc., and it also has antitumor, protection kidney, the effect such as antiviral.Abroad, this low cost vegetable plant water extract is often applied in Food & Drink, has been prepared into and has necessarily releived, the functional food of sleeping effect.
Although the root of kudzu vine, agate coffee, soybean, valerian all have certain mitigation to climacteric metancholia, not there is the product being primary raw material with this Four Plants or its extract in market, and the spirit that is used for releiving, improve menopause symptom.
Summary of the invention
Based on the defect of prior art, the object of first aspect present invention is, provides a kind of spirit of releiving also can improve the product of menopause symptom, is mainly used in the various symptoms solving climacteric or have the women of " stealthy climacteric " phenomenon to show.
Based on this object, instant component raw material and parts by weight are: kudzu root extract 4 ~ 10 parts, Maca extract 2 ~ 8 parts, isoflavones 3 ~ 8 parts, Valerian root P.E 1 ~ 7 part.
Further, component raw material and parts by weight are: kudzu root extract 4 ~ 6 parts, Maca extract 3 ~ 6 parts, isoflavones 2 ~ 5 parts, Valerian root P.E 1 ~ 4 part.
Further, product of the present invention can comprise sweetener 0.2 ~ 5 part.
Sweetener is oligosaccharides, glycitols or natural sweetener class.
Particularly, sweetener includes but not limited to one or more in oligoisomaltose, FOS, xylitol, antierythrite, stevioside, Talin, glycyrrhizin.
The form that product of the present invention can make is the regular dosage form of pharmaceutically prior art, includes but not limited to: tablet, capsule, particle, oral liquid.
Excipient type and the content of involved interpolation in above dosage form manufacturing process are prior art.
In addition, product of the present invention can be made into beverage or tea in bag, also can add in other food or drink.
The object of another aspect of the present invention is, provides a kind of spirit of releiving also can improve the preparation method of menopause symptom product, comprises the steps:
(1) preparation of kudzu root extract: the root of kudzu vine is through stripping and slicing, drying, pulverizing, extract with 80% alcohol reflux, solid-liquid mass volume ratio (g/mL) is 1:10, refluxing extraction twice under 70 ~ 80 DEG C of conditions, the single-trial extraction time is 1.5 ~ 2.5h, reduced pressure concentration after filtrate merges, and removes solvent and obtains kudzu root extract, add maltodextrin as carrier, spraying dry makes powder.
(2) preparation of Valerian root P.E: valerian is through low temperature drying, pulverizing, extract with 70% alcohol reflux, solid-liquid mass volume ratio (g/mL) is 1:8, reflux twice under 45 DEG C of conditions, the single-trial extraction time is 1.5 ~ 2.5h, reduced pressure concentration after filtrate merges, and removes solvent and obtains valerian extract, add maltodextrin as carrier, spraying dry makes powder.
(3) after kudzu root extract, Maca extract, isoflavones, Valerian root P.E, sweetener proportionally being weighed, insert mixer, mix ten minutes, namely obtain product of the present invention, can compressing tablet, filled capsules be carried out according to production formulation requirement prior art or be diluted to oral liquid.
The root of kudzu vine in above-mentioned composition and Valerian root P.E, also can adopt solvent independent or mixing extract processing obtain extract.Described solvent refers to water and/or ethanol, and the method for solvent extraction adopts the one in reflux extraction, decocting method, percolation, continuous extraction to extract separately or multiple mixing is extracted.
The present invention is by kudzu root extract, Maca extract, isoflavones and Valerian root P.E, rationally composite according to specific ratio, prepares the product that a kind of spirit of can releiving improves menopause symptom.
Isoflavone like substance in the root of kudzu vine and soybean presents economic benefits and social benefits regulating action in vivo, can increase skin elasticity, softening cardiovascular and cerebrovascular, improve osteoporosis, alleviate menopause symptom; Agate coffee alkene in agate coffee and macamide, by acting on hypothalamus and pituitary, can regulate internal system; Valerian root P.E plays inhibitory action to nerve center, has effect of tranquilizing and allaying excitement.
Above-mentioned Chinese and western quality plant raw material is passed through scientific compatibility, practice test by the present invention, prepare safely, the product that has no side effect, the endocrinopathy that can effectively prevent Menopause to cause, adjustment female incretion balances, alleviate involutional various symptom, to releive spirit, alleviate inconvenience and puzzlement that menopause symptom causes the climacteric women state of mind and life aspect.
Detailed description of the invention
Below by specific embodiment, further technical scheme of the present invention is specifically described.Should be appreciated that, the following examples just as illustrating, and do not limit the scope of the invention, and the apparent change made according to the present invention of those skilled in the art simultaneously and modification are also contained within the scope of the invention.
Raw material: Maca extract, isoflavones, sweetener and auxiliary material are commercially available prod.
The preparation method of kudzu root extract: the root of kudzu vine is through stripping and slicing, drying, pulverizing, get root of kudzu vine powder 15g, by 80% ethanol 150mL refluxing extraction, refluxing extraction twice under 70 DEG C of conditions, the single-trial extraction time is 1.5h, reduced pressure concentration after filtrate merges, and removes solvent and obtains kudzu root extract, add maltodextrin as carrier, spraying dry makes powder.
The preparation method of Valerian root P.E: valerian is through low temperature drying, pulverizing, get valerian 10g, by 70% ethanol 80mL refluxing extraction, reflux twice under 45 DEG C of conditions, the single-trial extraction time is 1.5h, reduced pressure concentration after filtrate merges, and removes solvent and obtains valerian extract, add maltodextrin as carrier, spraying dry makes powder.
Embodiment 1
Get kudzu root extract 250g, Maca extract 200g, isoflavones 180g, Valerian root P.E 120g, stevioside 50g, add microcrystalline cellulose, starch, sodium carboxymethyl starch again, mixing, granulation, oven dry, whole grain, add dolomol compressing tablet, obtained tablet.
Embodiment 2
Get obtained kudzu root extract 180g and Maca extract 200g, isoflavones 120g, Valerian root P.E 120g mixes, then add stevioside 17g, Talin 3g, citric acid 120g, natural fruit powder 400g, mix, filling one-tenth solid beverage.
Embodiment 3
Get obtained kudzu root extract 220g and Maca extract 200g, isoflavones 200g, Valerian root P.E 200g, xylitol 70g, is mixed directly, and is filled into hard shell capsules, is prepared into health product capsule.
Spirit of releiving of the present invention also can improve the product of Menopause symptom, women's (comprising a part " recessive climacteric women ") that Stochastic choice 50 has climacteric syndrome tries out, take product of the present invention course for the treatment of (30 days), the menopause symptom of 42 people is improved, wherein 14 people's menopause symptoms improve effect is not clearly, but the state of mind is better than before.Take more than two courses for the treatment of, have the menopause symptom of 45 people to be improved, and Be very effective.
Be below model case:
Example 1: king so-and-so, female, at 46 years old age, symptom is: hot flash, uncomfortable in chest, insomnia, oversensitive emotional, has a pain in the back, and to take after embodiment 3 product 1 month, involutional symptom is alleviated substantially, without any discomfort.
Example 2: Lee so-and-so, female, at 38 years old age, symptom is: stature loses shape, and complexion is dull, insomnia and dreamful sleep, irritable, and sexual desire is cold.To take after embodiment 2 product 1 month, sleep good, in high spirits, the colour of skin is glossy, and sexual life is normal.
Example 3: Zheng, female, at 50 years old age, symptom is: insomnia and dreamful sleep, oversensitive emotional, and complexion is dull, and anxiety, with depression, uncomfortable in chestly to be breathed hard.To take after embodiment 3 product 2 months, spirit is good, and sleep quality is good, happy.
Claims (10)
1. spirit of releiving also can improve a product for menopause symptom, and its component raw material is: kudzu root extract, Maca extract, isoflavones, Valerian root P.E; The parts by weight of its component raw material are: kudzu root extract 10 parts, Maca extract 2 ~ 8 parts, isoflavones 3 ~ 8 parts, Valerian root P.E 1 ~ 7 part.
2. spirit of releiving also can improve a product for menopause symptom, and its component raw material is: kudzu root extract, Maca extract, isoflavones, Valerian root P.E; The parts by weight of its component raw material are: kudzu root extract is 6 parts, and Maca extract is 3 parts, and isoflavones is 4 ~ 7 parts, and Valerian root P.E is 1 ~ 4 part.
3. the product according to claims 1 or 2, is characterized in that: also comprise sweetener 0.2 ~ 5 part in described component raw material.
4. product according to claim 3, is characterized in that: described sweetener is one or more in oligoisomaltose, FOS, xylitol, antierythrite, stevioside, Talin, glycyrrhizin.
5. the product according to claim 1 ~ 2 or 4, is characterized in that: its formulation is: tablet, capsule, particle, oral liquid, beverage, tea in bag.
6. as described in claim 1 ~ 2, any one can be releived spirit can improve the preparation method of menopause symptom product, and its preparation process is as follows:
(1) preparation of kudzu root extract: the root of kudzu vine is through stripping and slicing, drying, pulverizing, extract with 80% alcohol reflux, solid-liquid mass volume ratio (g/mL) is 1:10, refluxing extraction twice under 70 ~ 80 DEG C of conditions, the single-trial extraction time is 1.5 ~ 2.5h, reduced pressure concentration after filtrate merges, and removes solvent and obtains kudzu root extract, add maltodextrin as carrier, spraying dry makes powder;
(2) preparation of Valerian root P.E: valerian is through low temperature drying, pulverizing, extract with 70% alcohol reflux, solid-liquid mass volume ratio (g/mL) is 1:8, reflux twice under 45 DEG C of conditions, the single-trial extraction time is 1.5 ~ 2.5h, reduced pressure concentration after filtrate merges, and removes solvent and obtains valerian extract, add maltodextrin as carrier, spraying dry makes powder;
(3) after kudzu root extract, Maca extract, isoflavones, Valerian root P.E proportionally being weighed, insert mixer, mix ten minutes, namely obtain described product.
7. as described in claim 3 ~ 5, any one can be releived spirit can improve the preparation method of menopause symptom product, and its preparation process is as follows:
(1) preparation of kudzu root extract: the root of kudzu vine is through stripping and slicing, drying, pulverizing, extract with 80% alcohol reflux, solid-liquid mass volume ratio (g/mL) is 1:10, refluxing extraction twice under 70 ~ 80 DEG C of conditions, the single-trial extraction time is 1.5 ~ 2.5h, reduced pressure concentration after filtrate merges, and removes solvent and obtains kudzu root extract, add maltodextrin as carrier, spraying dry makes powder;
(2) preparation of Valerian root P.E: valerian is through low temperature drying, pulverizing, extract with 70% alcohol reflux, solid-liquid mass volume ratio (g/mL) is 1:8, reflux twice under 45 DEG C of conditions, the single-trial extraction time is 1.5 ~ 2.5h, reduced pressure concentration after filtrate merges, and removes solvent and obtains valerian extract, add maltodextrin as carrier, spraying dry makes powder;
(3) after kudzu root extract, Maca extract, isoflavones, Valerian root P.E, sweetener proportionally being weighed, insert mixer, mix ten minutes, namely obtain described product.
8. the preparation method of product according to claim 6 or 7, is characterized in that: step (1) or the reflux extraction method solvent extraction method described in (2) replace, and described solvent is water and/or ethanol.
9. the preparation method of product according to claim 8, is characterized in that: described solvent extraction method adopts the one in reflux extraction, decocting method, percolation, continuous extraction to extract separately or multiple mixing extraction.
10. a functional food, is characterized in that: described functional food is prepared by can releive spirit and the product treating climacteric metancholia of any one described in Claims 1 to 5.
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| CN104382977A (en) * | 2014-11-17 | 2015-03-04 | 昆明朗盛生物科技有限公司 | Special maca composition for women |
| KR101653678B1 (en) * | 2016-01-12 | 2016-09-02 | 주식회사 프롬바이오 | Food composition with Vitis vinifera seed extract, Valeriana officinalis extract, Carthamus tinctorius extract for prevention and relieving of menopausal symptoms |
| CN110367537A (en) * | 2019-08-08 | 2019-10-25 | 哈福科技（武汉）集团有限公司 | A kind of functional food and preparation method thereof improving menopausal syndrome |
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