CN102657791A - Chinese medicinal composition containing pale butterflybush flower and preparation method thereof - Google Patents
Chinese medicinal composition containing pale butterflybush flower and preparation method thereof Download PDFInfo
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- CN102657791A CN102657791A CN2012101806868A CN201210180686A CN102657791A CN 102657791 A CN102657791 A CN 102657791A CN 2012101806868 A CN2012101806868 A CN 2012101806868A CN 201210180686 A CN201210180686 A CN 201210180686A CN 102657791 A CN102657791 A CN 102657791A
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Abstract
The invention discloses a Chinese medicinal composition containing pale butterflybush flower, which comprises the following Chinese medicinal components in parts by weight: 5-50 parts of the pale butterflybush flower, 3-50 parts of lalang grass rhizome, 2-30 parts of common lophatherum herb and 0.5-10 parts of liquorice. The Chinese medicinal composition disclosed by the invention is rigorous in formula, contains fewer medicinal herbs, is specialized in drug efficacy and has the effects of clearing away heat and toxic materials, lowering fire, promoting the secretion of saliva or body fluid and the like, all the components are sourced from medicine-food homologous varieties, are safe to use, rich in nutrient substances and effective components for improving body health and treating diseases, and can supplement nutrition required by a human body and increase immunity.
Description
Technical field
The invention belongs to medicine, health food, field of food, relate to a kind of contain Flos Buddlejae can play Chinese medicine composition of heat-clearing toxin-expelling functions and preparation method thereof.
Background technology
Chinese medicine is the product of distinctive Chinese medical theory of China and practice; Aboundresources, with a long history, be the human pure natural organic material of using the earliest; Wherein part Chinese medicine often by people as food consumption; The very high medical value of tool again, promptly " integration of edible and medicinal herbs " kind has the two-way function of nutrition and treatment concurrently.
The modern owing to be busy with one's work, at ordinary times diet reason such as do not note, cause the health of much human all to be in sub-health state, will develop into disease even threat to life as not noting.Along with growth in the living standard, people are to health also pay attention to day by day, so the product that hope is used also is safely and effectively, and " integration of edible and medicinal herbs " type Chinese medicine meets people's treatment disease, health care demand.At present " integration of edible and medicinal herbs " type Chinese medicine is had more research, but Shang Weijian there is the report of Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri and Radix Glycyrrhizae compositions.
(1) Flos Buddlejae is dry flower and the inflorescence thereof of loganiaceae plant Flos Buddlejae Buddleja officinalis Maxim.." record of Chinese pharmacopoeia version in 2010: [nature and flavor with return through] are sweet, are slightly cold, and return Liver Channel; [function with cure mainly] heat clearing away nourishing the liver, improving acuity of vision and removing nebula is used for: conjunctival congestion and swelling pain, many tear photophobia, the nebula of looking unfamiliar film, hepatasthenia dim eyesight, blurring of vision." Kaibao Bencao ": sweet in the mouth, be slightly cold, nontoxic." book on Chinese herbal medicine is looked for the truth ": flavor is thinner than gas, the medicine of assistant to nourish blood, more effectively here.It is yellow that the Flos Buddlejae hot-water soak is, and good stability, strong coloring force, and aromatic odor is arranged, and therefore the Flos Buddlejae hot-water soak liquid that utilizes among the people is for many years made food color perfumings such as multicolored meal, is xanchromatic raw material sources in the Zhuang " multicolored glutinous rice ".Wei Xianfei, Huang Yunkun publish an article, and " toxicological assessment of Yellow plgment of buterflybush flower " (" Guangxi prevention science ": toxicology test result 1998,4 (4)) shows, the Flos Buddlejae safety non-toxic.
Flos Buddlejae contains compositions such as several amino acids, vitamin, trace element, flavone and glycoside thereof, triterpene saponin, flavochrome.The inventor entrusts Analysis-Test Research Center, Guangxi Zhuang Autonomous Region to detect and finds that Flos Buddlejae contains 17 seed amino acids of alanine, valine, leucine, isoleucine, proline, phenylalanine, methionine, glycine, serine, tyrosine, lysine, arginine, histidine, Aspartic Acid, glutamic acid, cystine, threonine needed by human body, abundant vitamin and wholesome trace element.Flavone and glycoside composition thereof have: spica contains buddleo-glucoside, acacetin, apigenin, luteolin, linarin, the new glycoside of Flos Buddlejae, cosmosin, apigenin-7-O-rutinoside, luteolin-7-O-glucoside, verbascoside, different foreign ligustrin.The triterpene saponin constituents has: Flos Buddlejae glycosides A, Flos Buddlejae glycosides B.The main chemical of its flavochrome is a crocin, and is consistent with the croceous active ingredient of rare Chinese medicine, has antioxidation, antidepressant and active anticancer effect." the Flos Buddlejae total flavones antioxidant activity " that Cai Lingyun etc. deliver (" spectroscopic test chamber " the 3rd phase in 2011): use the antioxidation activity in vitro size of the DPPH free radical scavenging activity being investigated Flos Buddlejae; And do comparison with Vc with concentration; The result shows; Flos Buddlejae is stronger than Vc to the effect of DPPH free radical scavenging, and Flos Buddlejae is a kind of good Natural antioxidant.
(2) Rhizoma Imperatae is the dry rhizome of grass Herba Imperatae Imperata cylindrica Beauv.var.major (Nees) C.E.Hubb.." record of Chinese pharmacopoeia version in 2010: [nature and flavor with return through] are sweet, cold, return lung, stomach, urinary bladder channel; [function with cure mainly] cooling blood for hemostasis, clearing away heat and promoting diuresis are used for heat in blood haematemesis, epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria, acute nephritis edema.In " about the notice of further standard healthy food material management " announced for Ministry of Public Health 2002 be food be again one of drug list.
Rhizoma Imperatae mainly contains volume sucrose, glucose, a small amount of fructose, xylose and citric acid, oxalic acid, malic acid etc., and is still starch-containing.Other has report from the Herba Imperatae rhizome, to isolate arundoin, Cylindrin, Coixol, fernenol, simiarenol, Isoarborinol alcohol, Anemonin, stigmasterol, cupreol, campesterol etc.Modern pharmacological research shows that Rhizoma Imperatae has: diuresis, antibiotic, hemostasis, reduce effect such as vascular permeability.
(3) Herba Lophatheri is the dry stem and leaf of grass Herba Lophatheri Lophatherum gracile Brongn.." record of Chinese pharmacopoeia version in 2010: [nature and flavor with return through] are sweet, light, cold, GUIXIN, stomach, small intestine meridian; [function with cure mainly] clearing heat and relieving fidgetness, diuresis are used for the calentura excessive thirst, hot urination drenches pain, aphtha of the mouth and tongue.In " about the notice of further standard healthy food material management " announced for Ministry of Public Health 2002 be food be again one of drug list.
Herba Lophatheri contains a large amount of flavone compounds and bioactive polysaccharide and other effective ingredient, like phenolic acid compound, anthraquinone analog compound, terpene lactone, extraordinary aminoacid and active skin, manganese, zinc, selenium and other trace elements.Other has report to contain arundoin, Cylindrin, taraxasterol, freidelin, stigmasterol, cupreol, campesterol etc.Wherein contained functional factor mainly is flavone glycoside and Coumarins lactone, and its content and biological activity that effectively becomes all has comparability with Folium Ginkgo.Modern pharmacological research shows that Herba Lophatheri has refrigeration function, and other has the effect of good free radical resisting, antioxidation, defying age, blood fat reducing and cholesterolemia.
(4) Radix Glycyrrhizae is the dry root and rhizome of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L.." record of Chinese pharmacopoeia version in 2010: [nature and flavor with return through] are sweet, flat, GUIXIN, lung, spleen, stomach warp; [function with cure mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription are used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.In " about the notice of further standard healthy food material management " announced for Ministry of Public Health 2002 be food be again one of drug list.
Radix Glycyrrhizae mainly contains saponin, flavonoid, Coumarins, alkaloids and compound of polysaccharide.Saponins compound divides triterpene saponin and diterpene saponin: triterpenes mainly contains glycyrrhizic acid and potassium calcium salt, glycyrrhizin etc.; Diterpenes mainly contains Glycyrrhiza uralensis Fisch. saponin A, B and glycyrrhizin A3, B2, C2, D3, E2, F3, G2, H2, J2, K2.Flavones ingredient has: Radix Glycyrrhizae aglycon, liquirtin, isoliquiritin unit, isoliquiritin, Neoliquiritin, licoflavone, Isolicoflavonol., glycyrrhizin, isoliquiritigenin, ononin etc.Coumarin kind compound mainly contains: glycycoumarin, glycyol, isoglycyol, Radix Glycyrrhizae coumarin-7-methyl ether etc.Alkaloids has 3,4-tetrahydroquinoline compounds.Polysaccharide has: Radix Glycyrrhizae dextran GBW, Angelica Polysaccharide UV, UB, UC, polysaccharide GR2IIa, gr2IIb, GR2IIc and polysaccharide GPS.Modern pharmacological research shows, effect such as Radix Glycyrrhizae has detoxifcation, antiinflammatory and resistance attitude, eliminates the phlegm, antitussive, inhibition gastric ulcer, spasmolytic, anti-liver injury, heart tonifying, anticancer, adrenocortical hormone appearance.
Summary of the invention
The purpose of this invention is to provide a kind of contain Flos Buddlejae can play Chinese medicine composition of heat-clearing toxin-expelling functions and preparation method thereof.
The inventor selects proper raw material from " integration of edible and medicinal herbs " type Chinese medicine; Through reasonable preparation, process a kind of Chinese medicine composition that contains Flos Buddlejae, this Chinese medicine composition contains rich nutrient substances and treatment disease and the effective ingredient that improves health; And there are pleasant aromatic odor, mouthfeel good; Add and to be prepared into health food or foodstuff product in right amount, can replenish needed by human body nutrition, improve immunity, the purpose of reach health care, looks improving and the skin nourishing, relieving stress, improving the quality of living.
The technical scheme that the present invention adopted is following:
A kind of Chinese medicine composition that contains Flos Buddlejae is made up of the Chinese medicinal components of following weight part ratio: Flos Buddlejae 5-50 part, Rhizoma Imperatae 3-50 part, Herba Lophatheri 2-30 part, Radix Glycyrrhizae 0.5-10 part.As preferably, the described Chinese medicine composition that contains Flos Buddlejae is made up of the Chinese medicinal components of following weight part ratio: Flos Buddlejae 8-25 part, Rhizoma Imperatae 5-20 part, Herba Lophatheri 3-15 part, Radix Glycyrrhizae 1-5 part.Wherein said Rhizoma Imperatae, Herba Lophatheri can be bright article.
The above-described Chinese medicine composition that contains Flos Buddlejae; Can be prepared into solid preparation or liquid preparation; The preparation that for example allows on medicine, health food, the food, as: powder, granule (electuary), pill, tablet, capsule, decoction, mixture (comprising oral liquid), syrup, medicated wine, beverage (comprising herbal tea), tea-drinking (comprising teabag, tea piece) etc.As preferably, said solid preparation is capsule or teabag, and said liquid preparation is oral liquid or beverage.
Extraction is the committed step of preparation.The extraction of middle pharmaceutically active ingredient is the process of a complicacy; After the Chinese medicine sample added solvent, solvent was through soaking diffusion, and the chemical constituent that Chinese medicine is contained is dissolved gradually; It is diffused in the solvent, and the concentration of dissolved chemical constituent reaches balance in the solution inside and outside cell.Therefore, in leaching process, the degree of grinding of Chinese medicine, extraction temperature, time, number of times, solvent etc. all are the factors that influence is extracted, and select rational condition for use, could improve extraction ratio of effective constituents, reach different results of use.
The above-mentioned Chinese medicine composition that contains Flos Buddlejae is prepared into the method for distilling of preparation, may further comprise the steps:
(1) gets Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae respectively, clean drying;
(2) by weight than taking by weighing: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) the independent respectively or any several flavors of load weighted Chinese medicine are merged, add ethanol extraction 1-3 time of 5-15 times of water gaging or 20-75% concentration, each 0.5-3 hour, temperature was 60-100 ℃, filtration, and merging filtrate promptly gets.
The above-mentioned Chinese medicine composition that contains Flos Buddlejae is prepared into capsular method, may further comprise the steps:
(1) gets Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae respectively, clean drying;
(2) by weight than taking by weighing: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) the independent respectively or any several flavors of load weighted Chinese medicine are merged, add ethanol extraction 1-3 time of 5-15 times of water gaging or 20-75% concentration, each 0.5-3 hour, temperature was 60-100 ℃, filtration, merging filtrate;
(4) filtrating is condensed into thick paste, drying is pulverized;
(5) add filler, lubricant, mixing incapsulates, and promptly gets.
Wherein said filler is well known to those of ordinary skill in the art; As: one or more combinations in starch, microcrystalline Cellulose, lactose, dextrin, the pregelatinized Starch etc., said lubricant is one or more combinations in magnesium stearate, Pulvis Talci, the silicon dioxide etc.
The above-mentioned Chinese medicine composition that contains Flos Buddlejae is prepared into the method for oral liquid, may further comprise the steps:
(1) gets Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae respectively, clean drying;
(2) by weight than taking by weighing: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) the independent respectively or any several flavors of load weighted Chinese medicine are merged, add ethanol extraction 1-3 time of 5-15 times of water gaging or 20-75% concentration, each 0.5-3 hour, temperature was 60-100 ℃, filtration, merging filtrate;
(4) will filtrate and concentrate, add stabilizing agent, antiseptic, correctives, mixing;
(5) filter, add suitable quantity of water, mixing, sterilization promptly gets.
The above-mentioned Chinese medicine composition that contains Flos Buddlejae is prepared into the method for beverage, may further comprise the steps:
(1) gets Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae respectively, clean drying;
(2) by weight than taking by weighing: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) the independent respectively or any several flavors of load weighted Chinese medicine are merged, add ethanol extraction 1-3 time of 5-15 times of water gaging or 20-75% concentration, each 0.5-3 hour, temperature was 60-100 ℃, filtration, merging filtrate;
(4) add stabilizing agent, antiseptic, correctives, mixing;
(5) filter, add suitable quantity of water, mixing, sterilization promptly gets.
Stabilizing agent described in above oral liquid, the beverage preparation is well known to those of ordinary skill in the art; As: arabic gum, xanthan gum, sodium alginate, lecithin; The combination of one or more in fatty glyceride, Polysorbate, starch slurry, methylcellulose, sodium carboxymethyl cellulose, hydroxyethyl-cellulose, hydroxypropyl cellulose, carbomer, polyvidone, glucosan, citrate, tartrate, phosphate and the chloride etc.; Said antiseptic is one or more the combination in benzoic acid, sodium benzoate, methyl parahydroxybenzoate, ethylparaben, sorbic acid, the potassium sorbate etc., and said correctives is one or more the combination in sucrose, simple syrup, sorbitol, mannitol, stevioside, the radix asparagi sweet extract etc.
The above-mentioned Chinese medicine composition that contains Flos Buddlejae is prepared into the method for teabag, may further comprise the steps:
(1) gets Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae respectively, clean, clean drying;
(2) by weight than taking by weighing: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) load weighted Chinese medicine is pulverized, crossed the 20-100 mesh sieve;
(4) mixing, pack, sealing, sterilization, mechanical packaging promptly gets.
The Chinese medicine composition that the present invention contains Flos Buddlejae is on the basis of Chinese medicine traditional theory, and in conjunction with medication experience among the people, the utilization modern scientific theory is formulated.Flos Buddlejae in the side has the effect of heat clearing away nourishing the liver, improving acuity of vision and removing nebula, is monarch drug; Rhizoma Imperatae is with the property principal drug assistance heat-clearing and toxic substances removing of cooling blood for hemostasis, clearing away heat and promoting diuresis, the merit of nourishing blood for improving eyesight, so be ministerial drug; Herba Lophatheri has clearing heat and relieving fidgetness, diuretic effect, is adjuvant drug; Radix Glycyrrhizae has the effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, is messenger drug; All medicines share and play altogether that heat-clearing and toxic substances removing, pathogenic fire reducing promote the production of body fluid, diuresis, make eye bright, nourish blood, the merit of function of spleen and stomach regulating.Prescription of the present invention is rigorous, and parum drug and centralize the power drenches from the beginning of, edema, hot urination to calentura excessive thirst, aphtha of the mouth and tongue, pharyngolaryngitis, anemopyretic cold that pain, conjunctival congestion and swelling pain, heat in blood are hemorrhage, weakness of the spleen and stomach has good curative effect.
The invention has the beneficial effects as follows:
(1) component is all taken from " integration of edible and medicinal herbs " kind, and is safe in utilization.
(2) prescription is rigorous; Parum drug and centralize the power; Have that heat-clearing and toxic substances removing, pathogenic fire reducing promote the production of body fluid, diuresis, make eye bright, nourish blood, the effect of function of spleen and stomach regulating, calentura excessive thirst, aphtha of the mouth and tongue, pharyngolaryngitis, anemopyretic cold drenched from the beginning of, edema, hot urination pain, conjunctival congestion and swelling pain, heat in blood are hemorrhage, weakness of the spleen and stomach has good curative effect.
(3) contain rich nutrient substances and improve health and treatment disease effective ingredient; And there are pleasant aromatic odor, mouthfeel good; Add and be prepared into health food or foodstuff product in right amount; Can replenish needed by human body nutrition, improve immunity, the purpose of reach health care, looks improving and the skin nourishing, relieving stress, improving the quality of living.
The specific embodiment
Below in conjunction with specific embodiment the present invention is further described, but does not limit protection scope of the present invention and range of application:
One, the preparation of capsule
1. EXPERIMENTAL DESIGN:
This test is prepared into capsule respectively with 8 embodiment, and concrete parameter sees table 1 for details.
Table 1 capsule embodiment preparation parameter table
* Flos Buddlejae is used 75% ethanol extraction among remarks: the embodiment 6, and all the other flavour of a drug are used water extraction.
2. operating procedure:
(1) gets Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae respectively, clean drying;
(2) take by weighing respectively by the listed parameter of table 1: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) load weighted Chinese medicine is pressed the listed parameter of table 1, respectively independent or any several flavors merge, and add ethanol extraction 1-3 time of 5-15 times of water gaging or 20-85% concentration, and each 0.5-3 hour, temperature was 60-100 ℃, filtration, merging filtrate;
(4) filtrating is condensed into thick paste, drying is pulverized;
(5) add an amount of filler, lubricant respectively by the listed parameter of table 1, mixing incapsulates, and promptly gets.
Two, the preparation of oral liquid
1. EXPERIMENTAL DESIGN:
This test is prepared into oral liquid respectively with 8 embodiment, and concrete parameter sees table 2 for details.
Table 2 oral liquid embodiment preparation parameter table
* remarks: 1. Flos Buddlejae, Herba Lophatheri are used 50% ethanol extraction among the embodiment 10, and all the other flavour of a drug are used water extraction.2. Flos Buddlejae is used 75% ethanol extraction among the embodiment 14, and all the other flavour of a drug are used water extraction.3. "/" expression does not add.
2. operating procedure:
(1) gets Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae respectively, clean drying;
(2) take by weighing respectively by the listed parameter of table 2: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) load weighted Chinese medicine is pressed the listed parameter of table 2, respectively independent or any several flavors merge, and add ethanol extraction 1-3 time of 5-15 times of water gaging or 20-85% concentration, and each 0.5-3 hour, temperature was 60-100 ℃, filtration, merging filtrate;
(4) will filtrate and concentrate, add an amount of stabilizing agent, antiseptic, correctives, mixing;
(5) filter, add suitable quantity of water, mixing, sterilization promptly gets.
Three, the preparation of beverage
1. EXPERIMENTAL DESIGN:
This test is prepared into beverage respectively with 8 embodiment, and concrete parameter sees table 3 for details.
Table 3 beverage embodiment preparation parameter table
* remarks: 1. Flos Buddlejae, Herba Lophatheri are used 40% ethanol extraction among the embodiment 18, and all the other flavour of a drug are used water extraction.2. Flos Buddlejae is used 75% ethanol extraction among the embodiment 22, and all the other flavour of a drug are used water extraction.3. "/" expression does not add.
2. operating procedure:
(1) gets Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae respectively, clean drying;
(2) take by weighing respectively by the listed parameter of table 3: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) load weighted Chinese medicine is pressed the listed parameter of table 3, respectively independent or any several flavors merge, and add ethanol extraction 1-3 time of 5-15 times of water gaging or 20-85% concentration, and each 0.5-3 hour, temperature was 60-100 ℃, filtration, merging filtrate;
(4) add an amount of stabilizing agent, antiseptic, correctives, mixing;
(5) filter, add suitable quantity of water, mixing, sterilization promptly gets.
Four, the preparation of teabag
1. EXPERIMENTAL DESIGN:
This test is prepared into teabag respectively with 8 embodiment, and concrete parameter sees table 4 for details.
Table 4 teabag embodiment preparation parameter table
2. operating procedure:
(1) gets Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae respectively, clean, clean drying;
(2) take by weighing respectively by the listed parameter of table 4: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) load weighted Chinese medicine is pulverized, pressed the listed parameter of table 4 and cross the 20-100 mesh sieve respectively;
(4) mixing, pack, sealing, sterilization, mechanical packaging promptly gets.
Five, clinical practice
The present invention contains the Chinese medicine composition of Flos Buddlejae, once is used for treatment and observes 731 routine patient or volunteers.With above-mentioned 32 kinds of embodiment samples that prepare, be respectively applied for following 4 kinds of dissimilar patients or volunteer.A: hemorrhage with calentura excessive thirst, aphtha of the mouth and tongue, heat in blood is cardinal symptom (totally 178 examples, male 86 examples, women 92 examples, 33.1 years old mean age); B: is cardinal symptom (totally 186 examples, male 95 examples, women 91 examples with anemopyretic cold from the beginning of, pharyngolaryngitis; 35.8 years old mean age), C: drenching pain with conjunctival congestion and swelling pain, hot urination is cardinal symptom (totally 180 examples, male 87 examples; Woman's 93 examples, 35.8 years old mean age), D: with edema, weakness of the spleen and stomach is cardinal symptom (totally 187 examples; Man's 88 examples, women 99 examples, 40.1 years old mean age).Each embodiment sample is used for above-mentioned four types case and is no less than 5 examples.Result: A group: recovery from illness 82%, improve 12%, invalid 6%, the B group: recovery from illness 80%, improve 13%, invalid 7%, the C group: recovery from illness 85%, improve 10%, invalid 5%, D recovery from illness 78% improves 14%, invalid 8%.The result shows: the various preparations that adopt Chinese medicine composition preparation of the present invention; Safe in utilization, effective; Calentura excessive thirst, aphtha of the mouth and tongue, pharyngolaryngitis, anemopyretic cold drenched from the beginning of, edema, hot urination pain, conjunctival congestion and swelling pain, heat in blood are hemorrhage, weakness of the spleen and stomach has good curative effect; Can replenish simultaneously needed by human body nutrition, improve immunity, the purpose of reach health care, looks improving and the skin nourishing, relieving stress, improving the quality of living.Below be several model cases:
Case 1: open * *, the woman, 32 years old, with calentura excessive thirst, aphtha of the mouth and tongue, heat in blood is hemorrhage is cardinal symptom.Take the capsule (embodiment 1) that Chinese medicine composition that the present invention contains Flos Buddlejae is processed, each 3 (0.5g/ grain) serve on 5 every day 3 times, and the gingival hemorrhage phenomenon stops, and the dispute skin ulcer disappears, and the excessive thirst symptom is eliminated, recovery from illness.
Case 2: the king * *, the man, 21 years old is cardinal symptom with anemopyretic cold from the beginning of, pharyngolaryngitis.Take the oral liquid (embodiment 14) that Chinese medicine composition that the present invention contains Flos Buddlejae is processed, each 1 (10ml/ props up) serve on 5 every day 3 times, and pharyngolaryngitis is eliminated, and throws off a cold.
Case 3: high * *, the man, 35 years old, drenching pain with conjunctival congestion and swelling pain, hot urination was cardinal symptom.Take the beverage (embodiment 20) that Chinese medicine composition that the present invention contains Flos Buddlejae is processed, serve on 31 bottle of every day (250ml/ bottle), the conjunctival congestion redness disappears, and it is unobstructed normal to urinate, recovery from illness.
Case 4: what * *, the woman, 45 years old is cardinal symptom with edema, weakness of the spleen and stomach.Take the teabag (embodiment 27) that Chinese medicine composition that the present invention contains Flos Buddlejae is processed, each 1 bag (5g/ bag) serve on 7 every day 3 times, and edema is eliminated, and spleen and stomach function strengthens, recovery from illness.
Claims (10)
1. a Chinese medicine composition that contains Flos Buddlejae is characterized in that being made up of the Chinese medicinal components of following weight part ratio: Flos Buddlejae 5-50 part, Rhizoma Imperatae 3-50 part, Herba Lophatheri 2-30 part, Radix Glycyrrhizae 0.5-10 part.
2. the Chinese medicine composition that contains Flos Buddlejae according to claim 1 is characterized in that being made up of the Chinese medicinal components of following weight part ratio: Flos Buddlejae 8-25 part, Rhizoma Imperatae 5-20 part, Herba Lophatheri 3-15 part, Radix Glycyrrhizae 1-5 part.
3. the Chinese medicine composition that contains Flos Buddlejae according to claim 1 and 2 is characterized in that said preparation of compositions becomes solid preparation or liquid preparation.
4. the Chinese medicine composition that contains Flos Buddlejae according to claim 3 is characterized in that said solid preparation is capsule or teabag, and said liquid preparation is oral liquid or beverage.
5. the method for preparing of a Chinese medicine composition that contains Flos Buddlejae according to claim 1 or claim 2 is characterized in that may further comprise the steps:
(1) gets Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae respectively, clean drying;
(2) by weight than taking by weighing: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) independent or any a few flavor merges with load weighted Chinese medicine, adds ethanol extraction 1-3 time of 5-15 times of water gaging or 20-75% concentration, and each 0.5-3 hour, temperature was 60-100 ℃, filtration, and merging filtrate promptly gets;
(4) above-mentioned filtrating is added suitable adjuvant, process capsule, oral liquid or beverage.
6. the method for preparing that contains the Chinese medicine composition of Flos Buddlejae according to claim 5 is characterized in that the method for preparing of said capsule also comprises: step (3) gained filtrating is condensed into thick paste, drying; Pulverize, add filler and lubricant then, mixing; Incapsulate, promptly get.
7. the method for preparing that contains the Chinese medicine composition of Flos Buddlejae according to claim 6 is characterized in that: said filler is one or more combinations in starch, microcrystalline Cellulose, lactose and the dextrin; Said lubricant is one or more combinations in magnesium stearate, Pulvis Talci and the silicon dioxide.
8. the method for preparing that contains the Chinese medicine composition of Flos Buddlejae according to claim 5 is characterized in that the method for preparing of said oral liquid also comprises: step (3) gained filtrating is concentrated, add stabilizing agent, antiseptic or correctives; Mixing filters, and adds suitable quantity of water; Mixing, sterilization promptly gets.
9. the method for preparing that contains the Chinese medicine composition of Flos Buddlejae according to claim 5 is characterized in that the method for preparing of said beverage also comprises: in step (3) gained filtrating, add stabilizing agent, antiseptic or correctives; Mixing filters, and adds suitable quantity of water; Mixing, sterilization promptly gets.
10. a Chinese medicine composition that contains Flos Buddlejae according to claim 1 or claim 2 is prepared into the method for teabag, it is characterized in that, may further comprise the steps:
(1) gets Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae respectively, clean, clean drying;
(2) by weight than taking by weighing: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) load weighted Chinese medicine is pulverized, crossed the 20-100 mesh sieve;
(4) mixing, pack, sealing, sterilization, mechanical packaging promptly gets.
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| CN106038701A (en) * | 2014-04-18 | 2016-10-26 | 温先敏 | Application of Flos Buddlejae and extract thereof in preparation of cardiac tumor disease treatment medicines |
| CN107372956A (en) * | 2017-07-28 | 2017-11-24 | 贵州杨老奶食品有限公司 | A kind of butterflybush flower tea and preparation method thereof |
| CN112970905A (en) * | 2021-03-27 | 2021-06-18 | 贵州医科大学 | Composite herbal tea beverage and preparation method thereof |
| CN114209606A (en) * | 2022-01-27 | 2022-03-22 | 广州巴泰新材料科技有限公司 | Antioxidant organic silicone oil cosmetic composition and preparation process thereof |
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| CN103690811A (en) * | 2013-12-23 | 2014-04-02 | 广西南宁科冠医药科技开发有限公司 | Traditional Chinese medicine oral liquid for lowering blood pressure and preventing dizziness and preparation method thereof |
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| CN106038701A (en) * | 2014-04-18 | 2016-10-26 | 温先敏 | Application of Flos Buddlejae and extract thereof in preparation of cardiac tumor disease treatment medicines |
| CN106038700A (en) * | 2014-04-18 | 2016-10-26 | 温先敏 | Application of butterflybush flower and extract in preparation of medicine for treating pulmonary heart disease |
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| CN107372956A (en) * | 2017-07-28 | 2017-11-24 | 贵州杨老奶食品有限公司 | A kind of butterflybush flower tea and preparation method thereof |
| CN112970905A (en) * | 2021-03-27 | 2021-06-18 | 贵州医科大学 | Composite herbal tea beverage and preparation method thereof |
| CN114209606A (en) * | 2022-01-27 | 2022-03-22 | 广州巴泰新材料科技有限公司 | Antioxidant organic silicone oil cosmetic composition and preparation process thereof |
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| CN102657791B (en) | 2014-11-12 |
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