CN102657791B - Chinese medicinal composition containing pale butterflybush flower and preparation method thereof - Google Patents
Chinese medicinal composition containing pale butterflybush flower and preparation method thereof Download PDFInfo
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- CN102657791B CN102657791B CN201210180686.8A CN201210180686A CN102657791B CN 102657791 B CN102657791 B CN 102657791B CN 201210180686 A CN201210180686 A CN 201210180686A CN 102657791 B CN102657791 B CN 102657791B
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Abstract
The invention discloses a Chinese medicinal composition containing pale butterflybush flower, which comprises the following Chinese medicinal components in parts by weight: 5-50 parts of the pale butterflybush flower, 3-50 parts of lalang grass rhizome, 2-30 parts of common lophatherum herb and 0.5-10 parts of liquorice. The Chinese medicinal composition disclosed by the invention is rigorous in formula, contains fewer medicinal herbs, is specialized in drug efficacy and has the effects of clearing away heat and toxic materials, lowering fire, promoting the secretion of saliva or body fluid and the like, all the components are sourced from medicine-food homologous varieties, are safe to use, rich in nutrient substances and effective components for improving body health and treating diseases, and can supplement nutrition required by a human body and increase immunity.
Description
Technical field
The invention belongs to medicine, health food, field of food, relate to a kind of containing Flos Buddlejae can play Chinese medicine composition of heat-clearing toxin-expelling functions and preparation method thereof.
Background technology
Chinese medicine is the product of the distinctive Chinese medical theory of China and practice, aboundresources, with a long history, it is the pure natural organic material that the mankind apply the earliest, wherein part Chinese medicine often by people as food consumption, the very high medical value of tool again, " integration of edible and medicinal herbs " kind, has the two-way function of nutrition and treatment concurrently.
Modern owing to being busy with one's work, at ordinary times diet the reason such as do not note, cause a lot of people's health all in sub-health state, if do not noted, will develop into even threat to life of disease.Along with growth in the living standard, people are to health also pay attention to day by day, therefore the product that hope is used is also safely and effectively, and " integration of edible and medicinal herbs " class Chinese medicine meets people's treatment disease, health care demand.At present " integration of edible and medicinal herbs " class Chinese medicine is had to more research, but there is not yet the report of Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri and Radix Glycyrrhizae compositions.
(1) Flos Buddlejae is dry flower and the inflorescence thereof of loganiaceae plant Flos Buddlejae Buddleja officinalis Maxim..< < Chinese Pharmacopoeia > > version in 2010 is recorded: [nature and flavor with return through] are sweet, are slightly cold, and return Liver Channel; [function with cure mainly] heat clearing away nourishing the liver, improving acuity of vision and removing nebula, for: conjunctival congestion and swelling pain, many tear photophobia, the nebula of looking unfamiliar film, hepatasthenia dim eyesight, blurring of vision.< < Kaibao Bencao > >: sweet in the mouth, be slightly cold, nontoxic.The < < book on Chinese herbal medicine > > that looks for the truth: taste is thinner than gas, the medicine of assistant to nourish blood, more effectively here.It is yellow that Flos Buddlejae hot-water soak is, and good stability, strong coloring force, has aromatic odor, and therefore the Flos Buddlejae hot-water soak liquid that utilizes among the people is made the food color perfumings such as multicolored meal for many years, is raw material sources yellow in Zhuang " multicolored glutinous rice ".Publish an article toxicological assessment > > (the < < Guangxi prevention science > >: 1998 of < < Yellow plgment of buterflybush flower of Wei Xianfei, Huang Yunkun, toxicology test result 4(4)) shows, Flos Buddlejae safety non-toxic.
Flos Buddlejae is containing compositions such as several amino acids, vitamin, trace element, flavone and glycoside thereof, triterpene saponin, flavochrome.Inventor entrusts Analysis-Test Research Center, Guangxi Zhuang Autonomous Region to detect and finds, Flos Buddlejae is containing alanine, valine, leucine, isoleucine, proline, phenylalanine, methionine, glycine, serine, tyrosine, lysine, arginine, histidine, Aspartic Acid, glutamic acid, cystine, 17 seed amino acids of threonine needed by human body, abundant vitamin and wholesome trace element.Flavone and methods of glycosides thereof have: spica is containing buddleo-glucoside, acacetin, apigenin, luteolin, linarin, Neobudofficide, cosmosin, apigenin-7-O-rutinoside, luteolin-7-O-glucoside, verbascoside, different foreign ligustrin.Triterpenoid saponins has: Flos Buddlejae glycosides A, Flos Buddlejae glycosides B.The main chemical of its flavochrome is crocin, consistent with the croceous active ingredient of rare Chinese medicine, has antioxidation, antidepressant and active anticancer effect.The < < Flos Buddlejae total flavones antioxidant activity > > (< < spectroscopic test chamber > > the 3rd phase in 2011) that Cai Lingyun etc. deliver: use the antioxidation activity in vitro size of DPPH free radical scavenging activity being investigated to Flos Buddlejae, and compare with the Vc of same concentration, result shows, Flos Buddlejae is stronger than Vc to the effect of DPPH free radical scavenging, and Flos Buddlejae is a kind of good Natural antioxidant.
(2) Rhizoma Imperatae is the dry rhizome of grass Herba Imperatae Imperata cylindrica Beauv.var.major (Nees) C.E.Hubb..< < Chinese Pharmacopoeia > > version in 2010 is recorded: [nature and flavor with return through] are sweet, cold, return lung, stomach, urinary bladder channel; [function with cure mainly] cooling blood for hemostasis, clearing away heat and promoting diuresis, for heat in blood haematemesis, epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria, acute nephritis edema.In the notice > > that the < < announcing for 2002 for Ministry of Public Health manages about further standard healthy food material, be one of food and drug list.
Rhizoma Imperatae is mainly containing volume sucrose, glucose, a small amount of fructose, xylose and citric acid, oxalic acid, malic acid etc., still starch-containing.Separately there is report from the rhizome of Herba Imperatae, to isolate arundoin, Cylindrin, Coixol, fernenol, simiarenol, Isoarborinol, Anemonin, stigmasterol, cupreol, campesterol etc.Modern pharmacological research shows, Rhizoma Imperatae has: diuresis, antibacterial, hemostasis, reduce the effects such as vascular permeability.
(3) Herba Lophatheri is the dry stem and leaf of grass Herba Lophatheri Lophatherum gracile Brongn..< < Chinese Pharmacopoeia > > version in 2010 is recorded: [nature and flavor with return through] are sweet, light, cold, GUIXIN, stomach, small intestine meridian; [function with cure mainly] clearing heat and relieving fidgetness, diuresis, drench pain, aphtha of the mouth and tongue for calentura excessive thirst, hot urination.In the notice > > that the < < announcing for 2002 for Ministry of Public Health manages about further standard healthy food material, be one of food and drug list.
Herba Lophatheri contains a large amount of flavone compounds and bioactive polysaccharide and other effective ingredient, as phenolic acid compound, anthraquinone analog compound, terpene lactone, extraordinary aminoacid and active skin, manganese, zinc, selenium and other trace elements.Separately there are report Arundoin, Cylindrin, taraxasterol, freidelin, stigmasterol, cupreol, campesterol etc.Wherein contained functional factor is mainly flavone glycoside and Coumarins lactone, and its content and biological activity effectively becoming all has comparability with Folium Ginkgo.Modern pharmacological research shows, Herba Lophatheri has refrigeration function, separately has the effect of good free radical resisting, antioxidation, defying age, blood fat reducing and cholesterolemia.
(4) Radix Glycyrrhizae is the dry root and rhizome of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L..< < Chinese Pharmacopoeia > > version in 2010 is recorded: [nature and flavor with return through] are sweet, flat, GUIXIN, lung, spleen, stomach warp; [function with cure mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.In the notice > > that the < < announcing for 2002 for Ministry of Public Health manages about further standard healthy food material, be one of food and drug list.
Radix Glycyrrhizae is mainly containing saponin, flavonoid, Coumarins, alkaloids and compound of polysaccharide.Saponins compound divides triterpene saponin and diterpene saponin: triterpenes mainly contains glycyrrhizic acid and potassium calcium salt, glycyrrhizin etc.; Diterpenes mainly contains Glycyrrhiza uralensis Fisch. saponin A, B and glycyrrhizin A3, B2, C2, D3, E2, F3, G2, H2, J2, K2.Flavones ingredient has: 4',7-Dihydroxyflavanone, liquirtin, isoliquiritin unit, isoliquiritin, Neoliquiritin, licoflavone, Isolicoflavonol., glycyrrhizin, isoliquiritigenin, ononin etc.Coumarin kind compound mainly contains: glycycoumarin, glycyol, isoglycyol, Radix Glycyrrhizae coumarin-7-methyl ether etc.Alkaloids has 3,4-tetrahydroquinoline compounds.Polysaccharide has: Radix Glycyrrhizae dextran GBW, Angelica Polysaccharide UV, UB, UC, polysaccharide GR2IIa, gr2IIb, GR2IIc and polysaccharide GPS.Modern pharmacological research shows, the effect such as Radix Glycyrrhizae has removing toxic substances, antiinflammatory and resistance state, eliminates the phlegm, antitussive, inhibition gastric ulcer, spasmolytic, anti-liver injury, heart tonifying, anticancer, adrenocortical hormone sample.
Summary of the invention
The object of this invention is to provide a kind of containing Flos Buddlejae can play Chinese medicine composition of heat-clearing toxin-expelling functions and preparation method thereof.
The inventor selects suitable raw material from " integration of edible and medicinal herbs " class Chinese medicine, pass through reasonable preparation, make a kind of Chinese medicine composition containing Flos Buddlejae, this Chinese medicine composition contains abundant nutrient substance and treatment disease and improves the effective ingredient of health, and there are pleasant aromatic odor, mouthfeel good, add and be prepared in right amount health food or foodstuff product, can supplement needed by human body nutrition, improve immunity, the object of reach health care, looks improving and the skin nourishing, relieving stress, improving the quality of living.
The technical solution adopted in the present invention is as follows:
Containing the Chinese medicine composition of Flos Buddlejae, by the Chinese medicinal components of following weight part ratio, formed: Flos Buddlejae 5-50 part, Rhizoma Imperatae 3-50 part, Herba Lophatheri 2-30 part, Radix Glycyrrhizae 0.5-10 part.As preferably, the described Chinese medicine composition containing Flos Buddlejae, is comprised of the Chinese medicinal components of following weight part ratio: Flos Buddlejae 8-25 part, Rhizoma Imperatae 5-20 part, Herba Lophatheri 3-15 part, Radix Glycyrrhizae 1-5 part.Wherein said Rhizoma Imperatae, Herba Lophatheri can be fresh goods.
The above-described Chinese medicine composition containing Flos Buddlejae, can be prepared into solid preparation or liquid preparation, the preparation for example allowing on medicine, health food, food, as: powder, granule (electuary), pill, tablet, capsule, decoction, mixture (comprising oral liquid), syrup, medicated wine, beverage (comprising herbal tea), tea-drinking (comprising teabag, tea piece) etc.As preferably, described solid preparation is capsule or teabag, and described liquid preparation is oral liquid or beverage.
Extraction is the committed step of preparation.The extraction of Effective Component of Chinese Medicine is a complicated process, when traditional Chinese medicine sample adds after solvent, solvent, by soaking diffusion, dissolves the chemical composition that Chinese medicine is contained gradually, it is diffused in solvent, until the concentration of dissolved chemical composition reaches balance in the inside and outside solution of cell.Therefore,, in leaching process, the degree of grinding of Chinese medicine, extraction temperature, time, number of times, solvent etc., be all the factor that impact is extracted, and selects rational condition, could improve the extraction ratio of effective ingredient, reaches different results of use.
The above-mentioned Chinese medicine composition containing Flos Buddlejae is prepared into the extracting method of preparation, comprises the following steps:
(1) get respectively Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae, clean, dry;
(2) take by weight: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) by load weighted Chinese medicine respectively independent or any several tastes merge, add ethanol extraction 1-3 time of 5-15 times of water gaging or 20-75% concentration, each 0.5-3 hour, temperature is 60-100 ℃, filtration, merging filtrate, obtains.
The above-mentioned Chinese medicine composition containing Flos Buddlejae is prepared into the method for capsule, comprises the following steps:
(1) get respectively Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae, clean, dry;
(2) take by weight: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) by load weighted Chinese medicine respectively independent or any several tastes merge, add ethanol extraction 1-3 time of 5-15 times of water gaging or 20-75% concentration, each 0.5-3 hour, temperature is 60-100 ℃, filtration, merging filtrate;
(4) filtrate is condensed into thick paste, dry, pulverize;
(5) add filler, lubricant, mix, incapsulate, obtain.
Wherein said filler is well known to those of ordinary skill in the art, as: one or more combinations in starch, microcrystalline Cellulose, lactose, dextrin, pregelatinized Starch etc., described lubricant is one or more combinations in magnesium stearate, Pulvis Talci, silicon dioxide etc.
The above-mentioned Chinese medicine composition containing Flos Buddlejae is prepared into the method for oral liquid, comprises the following steps:
(1) get respectively Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae, clean, dry;
(2) take by weight: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) by load weighted Chinese medicine respectively independent or any several tastes merge, add ethanol extraction 1-3 time of 5-15 times of water gaging or 20-75% concentration, each 0.5-3 hour, temperature is 60-100 ℃, filtration, merging filtrate;
(4) filtrate is concentrated, add stabilizing agent, antiseptic, correctives, mix;
(5) filter, add suitable quantity of water, mix, sterilizing, obtains.
The above-mentioned Chinese medicine composition containing Flos Buddlejae is prepared into the method for beverage, comprises the following steps:
(1) get respectively Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae, clean, dry;
(2) take by weight: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) by load weighted Chinese medicine respectively independent or any several tastes merge, add ethanol extraction 1-3 time of 5-15 times of water gaging or 20-75% concentration, each 0.5-3 hour, temperature is 60-100 ℃, filtration, merging filtrate;
(4) add stabilizing agent, antiseptic, correctives, mix;
(5) filter, add suitable quantity of water, mix, sterilizing, obtains.
Above oral liquid, described in beverage preparation, stabilizing agent is well known to those of ordinary skill in the art, as: arabic gum, xanthan gum, sodium alginate, lecithin, fatty glyceride, Polysorbate, starch slurry, methylcellulose, sodium carboxymethyl cellulose, hydroxyethyl-cellulose, hydroxypropyl cellulose, carbomer, polyvidone, glucosan, citrate, tartrate, the combination of one or more in phosphate and chloride etc., described antiseptic is benzoic acid, sodium benzoate, methyl parahydroxybenzoate, ethylparaben, sorbic acid, the combination of one or more in potassium sorbate etc., described correctives is sucrose, simple syrup, sorbitol, mannitol, stevioside, the combination of one or more in radix asparagi sweet extract etc.
The above-mentioned Chinese medicine composition containing Flos Buddlejae is prepared into the method for teabag, comprises the following steps:
(1) get respectively Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae, clean, clean, dry;
(2) take by weight: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) load weighted Chinese medicine is pulverized, crossed 20-100 mesh sieve;
(4) mix, pack, sealing, sterilizing, mechanical packaging, obtains.
The present invention is on the basis of Chinese medicine traditional theory containing the Chinese medicine composition of Flos Buddlejae, in conjunction with medication experience among the people, uses modern scientific theory formulated.Flos Buddlejae in side, has the effect of heat clearing away nourishing the liver, improving acuity of vision and removing nebula, is monarch drug; Rhizoma Imperatae is with the property principal drug assistance heat-clearing and toxic substances removing of cooling blood for hemostasis, clearing away heat and promoting diuresis, the merit of nourishing blood for improving eyesight, therefore be ministerial drug; Herba Lophatheri has the effect of clearing heat and relieving fidgetness, diuresis, is adjuvant drug; Radix Glycyrrhizae has the effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, for making medicine; All medicines share and play altogether that heat-clearing and toxic substances removing, pathogenic fire reducing promote the production of body fluid, diuresis, improving eyesight, nourish blood, the merit of function of spleen and stomach regulating.Prescription of the present invention is rigorous, and parum drug and centralize the power drenches from the beginning of, edema, hot urination to calentura excessive thirst, aphtha of the mouth and tongue, pharyngolaryngitis, anemopyretic cold that pain, conjunctival congestion and swelling pain, heat in blood are hemorrhage, weakness of the spleen and stomach has good curative effect.
The invention has the beneficial effects as follows:
(1) component is all taken from " integration of edible and medicinal herbs " kind, uses safety.
(2) prescription is rigorous, parum drug and centralize the power, have that heat-clearing and toxic substances removing, pathogenic fire reducing promote the production of body fluid, diuresis, improving eyesight, nourish blood, the effect of function of spleen and stomach regulating, calentura excessive thirst, aphtha of the mouth and tongue, pharyngolaryngitis, anemopyretic cold are drenched from the beginning of, edema, hot urination to pain, conjunctival congestion and swelling pain, heat in blood are hemorrhage, weakness of the spleen and stomach has good curative effect.
(3) contain abundant nutrient substance and improve health and treatment disease effective ingredient, and there are pleasant aromatic odor, mouthfeel good, add and be prepared in right amount health food or foodstuff product, can supplement needed by human body nutrition, improve immunity, the object of reach health care, looks improving and the skin nourishing, relieving stress, improving the quality of living.
The specific embodiment
Below in conjunction with specific embodiment, the invention will be further described, but do not limit the scope of the invention and range of application:
One, the preparation of capsule
1. EXPERIMENTAL DESIGN:
This test is prepared into respectively capsule with 8 embodiment, and design parameter refers to table 1.
Table 1 capsule embodiment preparation parameter table
* Flos Buddlejae 75% ethanol extraction in remarks: embodiment 6, all the other flavour of a drug water extraction.
2. operating procedure:
(1) get respectively Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae, clean, dry;
(2) by the listed parameter of table 1, take respectively: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) load weighted Chinese medicine is pressed to the listed parameter of table 1, respectively independent or any several tastes merge, and add ethanol extraction 1-3 time of 5-15 times of water gaging or 20-85% concentration, each 0.5-3 hour, and temperature is 60-100 ℃, filtration, merging filtrate;
(4) filtrate is condensed into thick paste, dry, pulverize;
(5) by the listed parameter of table 1, add respectively appropriate filler, lubricant, mix, incapsulate, obtain.
Two, the preparation of oral liquid
1. EXPERIMENTAL DESIGN:
This test is prepared into respectively oral liquid with 8 embodiment, and design parameter refers to table 2.
Table 2 oral liquid embodiment preparation parameter table
* remarks: 1. Flos Buddlejae, Herba Lophatheri 50% ethanol extraction in embodiment 10, all the other flavour of a drug water extraction.2. Flos Buddlejae 75% ethanol extraction in embodiment 14, all the other flavour of a drug water extraction.3. "/" represents not add.
2. operating procedure:
(1) get respectively Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae, clean, dry;
(2) by the listed parameter of table 2, take respectively: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) load weighted Chinese medicine is pressed to the listed parameter of table 2, respectively independent or any several tastes merge, and add ethanol extraction 1-3 time of 5-15 times of water gaging or 20-85% concentration, each 0.5-3 hour, and temperature is 60-100 ℃, filtration, merging filtrate;
(4) filtrate is concentrated, add appropriate stabilizing agent, antiseptic, correctives, mix;
(5) filter, add suitable quantity of water, mix, sterilizing, obtains.
Three, the preparation of beverage
1. EXPERIMENTAL DESIGN:
This test is prepared into respectively beverage with 8 embodiment, and design parameter refers to table 3.
Table 3 beverage embodiment preparation parameter table
* remarks: 1. Flos Buddlejae, Herba Lophatheri 40% ethanol extraction in embodiment 18, all the other flavour of a drug water extraction.2. Flos Buddlejae 75% ethanol extraction in embodiment 22, all the other flavour of a drug water extraction.3. "/" represents not add.
2. operating procedure:
(1) get respectively Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae, clean, dry;
(2) by the listed parameter of table 3, take respectively: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) load weighted Chinese medicine is pressed to the listed parameter of table 3, respectively independent or any several tastes merge, and add ethanol extraction 1-3 time of 5-15 times of water gaging or 20-85% concentration, each 0.5-3 hour, and temperature is 60-100 ℃, filtration, merging filtrate;
(4) add appropriate stabilizing agent, antiseptic, correctives, mix;
(5) filter, add suitable quantity of water, mix, sterilizing, obtains.
Four, the preparation of teabag
1. EXPERIMENTAL DESIGN:
This test is prepared into respectively teabag with 8 embodiment, and design parameter refers to table 4.
Table 4 teabag embodiment preparation parameter table
2. operating procedure:
(1) get respectively Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae, clean, clean, dry;
(2) by the listed parameter of table 4, take respectively: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) load weighted Chinese medicine is pulverized, by the listed parameter of table 4, crossed respectively 20-100 mesh sieve;
(4) mix, pack, sealing, sterilizing, mechanical packaging, obtains.
Five, clinical practice
The present invention is containing the Chinese medicine composition of Flos Buddlejae, is once used for the treatment of and observes 731 routine patient or volunteers.By above-mentioned 32 kinds of embodiment samples that prepare, be respectively used to following 4 kinds of dissimilar patients or volunteer.A: take calentura excessive thirst, aphtha of the mouth and tongue, heat in blood hemorrhage be cardinal symptom (totally 178 examples, man's 86 examples, female's 92 examples, 33.1 years old mean age), B: the anemopyretic cold of take is cardinal symptom (totally 186 examples from the beginning of, pharyngolaryngitis, man's 95 examples, female's 91 examples, 35.8 years old mean age), C: take conjunctival congestion and swelling pain, hot urination drenches pain as cardinal symptom (totally 180 examples, man's 87 examples, female's 93 examples, 35.8 years old mean age), D: take edema, weakness of the spleen and stomach as cardinal symptom (totally 187 examples, man's 88 examples, female's 99 examples, 40.1 years old mean age).Each embodiment sample is no less than 5 examples for the case of above-mentioned Four types.Result: A group: recovery from illness 82%, improve 12%, invalid 6%, B group: recovery from illness 80%, improve 13%, invalid 7%, C group: recovery from illness 85%, improve 10%, invalid 5%, D recovery from illness 78%, improves 14%, invalid 8%.Result shows: the various preparations that adopt Chinese medicine composition of the present invention to prepare, use safety, effective, calentura excessive thirst, aphtha of the mouth and tongue, pharyngolaryngitis, anemopyretic cold are drenched from the beginning of, edema, hot urination to pain, conjunctival congestion and swelling pain, heat in blood are hemorrhage, weakness of the spleen and stomach has good curative effect, can supplement simultaneously needed by human body nutrition, improve immunity, the object of reach health care, looks improving and the skin nourishing, relieving stress, improving the quality of living.Be below several model cases:
Case 1: * *, female, 32 years old, take calentura excessive thirst, aphtha of the mouth and tongue, heat in blood is hemorrhage is cardinal symptom.Take the capsule (embodiment 1) that the present invention makes containing the Chinese medicine composition of Flos Buddlejae, each 3 (0.5g/ grain), every day 3 times, serve on 5, and gingival hemorrhage phenomenon stops, and dispute skin ulcer disappears, and excessive thirst symptom is eliminated, recovery from illness.
Case 2: king * *, man, 21 years old, the anemopyretic cold of take was cardinal symptom from the beginning of, pharyngolaryngitis.Take the oral liquid (embodiment 14) that the present invention makes containing the Chinese medicine composition of Flos Buddlejae, each 1 (10ml/ props up), every day 3 times, serve on 5, and pharyngolaryngitis is eliminated, and throws off a cold.
Case 3: high * *, man, 35 years old, take conjunctival congestion and swelling pain, hot urination, to drench pain be cardinal symptom.Take the beverage (embodiment 20) that the present invention makes containing the Chinese medicine composition of Flos Buddlejae, 1 bottle of every day (250ml/ bottle), serve on 3, conjunctival congestion redness disappears, and urine is unobstructed normal, recovery from illness.
Case 4: what * *, female, 45 years old, take edema, weakness of the spleen and stomach was cardinal symptom.Take the teabag (embodiment 27) that the present invention makes containing the Chinese medicine composition of Flos Buddlejae, each 1 bag (5g/ bag), every day 3 times, serve on 7, and edema is eliminated, and spleen and stomach function strengthens, recovery from illness.
Claims (9)
1. containing a Chinese medicine composition for Flos Buddlejae, it is characterized in that, raw material is comprised of the Chinese medicinal components of following weight portion: Flos Buddlejae 8-25 part, Rhizoma Imperatae 5-20 part, Herba Lophatheri 3-15 part, Radix Glycyrrhizae 1-5 part.
2. the Chinese medicine composition containing Flos Buddlejae according to claim 1, is characterized in that described compositions is prepared into solid preparation or liquid preparation.
3. the Chinese medicine composition containing Flos Buddlejae according to claim 2, is characterized in that described solid preparation is capsule or teabag, and described liquid preparation is oral liquid or beverage.
4. the Chinese medicine composition containing Flos Buddlejae as claimed in claim 3 is prepared into a preparation method for preparation, it is characterized in that comprising the following steps:
(1) get respectively Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae, clean, dry;
(2) take by weight: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) load weighted Chinese medicine is independent or any a few taste merges, and adds ethanol extraction 1-3 time of 5-15 times of water gaging or 20-75% concentration, each 0.5-3 hour, and temperature is 60-100 ℃, filtration, merging filtrate, obtains;
(4) above-mentioned filtrate is added to suitable adjuvant, make capsule, oral liquid or beverage.
5. the Chinese medicine composition containing Flos Buddlejae according to claim 4 is prepared into the preparation method of preparation, the preparation method that it is characterized in that described capsule also comprises: step (3) gained filtrate is condensed into thick paste, dry, pulverize, then add filler and lubricant, mix, incapsulate, obtain.
6. the Chinese medicine composition containing Flos Buddlejae according to claim 5 is prepared into the preparation method of preparation, it is characterized in that: described filler is one or more combinations in starch, microcrystalline Cellulose, lactose and dextrin; Described lubricant is one or more combinations in magnesium stearate, Pulvis Talci and silicon dioxide.
7. the Chinese medicine composition containing Flos Buddlejae according to claim 4 is prepared into the preparation method of preparation, the preparation method that it is characterized in that described oral liquid also comprises: step (3) gained filtrate is concentrated, add stabilizing agent, antiseptic or correctives, mix, filter, add suitable quantity of water, mix, sterilizing, obtains.
8. the Chinese medicine composition containing Flos Buddlejae according to claim 4 is prepared into the preparation method of preparation, the preparation method that it is characterized in that described beverage also comprises: in step (3) gained filtrate, add stabilizing agent, antiseptic or correctives, mix, filter, add suitable quantity of water, mix, sterilizing, obtains.
9. the Chinese medicine composition containing Flos Buddlejae as claimed in claim 3 is prepared into a method for teabag, it is characterized in that, comprises the following steps:
(1) get respectively Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae, clean, clean, dry;
(2) take by weight: Flos Buddlejae, Rhizoma Imperatae, Herba Lophatheri, Radix Glycyrrhizae;
(3) load weighted Chinese medicine is pulverized, crossed 20-100 mesh sieve;
(4) mix, pack, sealing, sterilizing, mechanical packaging, obtains.
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Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103690811A (en) * | 2013-12-23 | 2014-04-02 | 广西南宁科冠医药科技开发有限公司 | Traditional Chinese medicine oral liquid for lowering blood pressure and preventing dizziness and preparation method thereof |
| CN103735896A (en) * | 2013-12-23 | 2014-04-23 | 广西南宁科冠医药科技开发有限公司 | Traditional Chinese medicine oral liquid for lowering blood pressure and preventing dizziness and preparation method thereof |
| CN106063815A (en) * | 2014-04-18 | 2016-11-02 | 温先敏 | Flos Buddlejae and extract thereof treat the application of the medicine of vascular lesion as preparation |
| CN105878258B (en) * | 2016-06-03 | 2018-07-20 | 新疆维吾尔自治区维吾尔医药研究所 | Purposes of the acteoside in preparing antidepressant |
| CN107372956A (en) * | 2017-07-28 | 2017-11-24 | 贵州杨老奶食品有限公司 | Butterflybush flower tea and preparation method thereof |
| CN112970905A (en) * | 2021-03-27 | 2021-06-18 | 贵州医科大学 | Composite herbal tea beverage and preparation method thereof |
| CN114209606B (en) * | 2022-01-27 | 2023-05-23 | 广州巴泰新材料科技有限公司 | Antioxidant organic silicone oil cosmetic composition and preparation process thereof |
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| CN1208076A (en) * | 1998-08-11 | 1999-02-17 | 曾昭荣 | Yinhua wine and its preparation |
| CN1672589A (en) * | 2004-03-24 | 2005-09-28 | 深圳市千金方生物技术有限公司 | Health beverage for people with overbundance Yang and its prepn process |
| CN101085962A (en) * | 2007-06-25 | 2007-12-12 | 吴江市方霞企业信息咨询有限公司 | Wine of bamboo and cogongrass |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3978517B2 (en) * | 1997-07-25 | 2007-09-19 | 株式会社ロッテ | Anti-Legionella composition |
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|---|---|---|---|---|
| CN1208076A (en) * | 1998-08-11 | 1999-02-17 | 曾昭荣 | Yinhua wine and its preparation |
| CN1672589A (en) * | 2004-03-24 | 2005-09-28 | 深圳市千金方生物技术有限公司 | Health beverage for people with overbundance Yang and its prepn process |
| CN101085962A (en) * | 2007-06-25 | 2007-12-12 | 吴江市方霞企业信息咨询有限公司 | Wine of bamboo and cogongrass |
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