CN104203808B - 具有纳米结构电极的生物传感器 - Google Patents
具有纳米结构电极的生物传感器 Download PDFInfo
- Publication number
- CN104203808B CN104203808B CN201280071882.XA CN201280071882A CN104203808B CN 104203808 B CN104203808 B CN 104203808B CN 201280071882 A CN201280071882 A CN 201280071882A CN 104203808 B CN104203808 B CN 104203808B
- Authority
- CN
- China
- Prior art keywords
- microfluidic device
- substrate
- sensor
- reagent
- working electrode
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Materials Engineering (AREA)
- Clinical Laboratory Science (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Dispersion Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Composite Materials (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Electrochemistry (AREA)
- Molecular Biology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2012/051170 WO2013136115A1 (en) | 2012-03-13 | 2012-03-13 | Biosensor having nanostrucured electrodes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104203808A CN104203808A (zh) | 2014-12-10 |
| CN104203808B true CN104203808B (zh) | 2017-06-09 |
Family
ID=46022501
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280071882.XA Expired - Fee Related CN104203808B (zh) | 2012-03-13 | 2012-03-13 | 具有纳米结构电极的生物传感器 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20150047978A1 (enExample) |
| EP (1) | EP2825501A1 (enExample) |
| JP (1) | JP6013519B2 (enExample) |
| CN (1) | CN104203808B (enExample) |
| IN (1) | IN2014DN08308A (enExample) |
| WO (1) | WO2013136115A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012327218C1 (en) | 2011-11-30 | 2015-12-24 | Wellstat Diagnostics, Llc. | Filtration Module |
| US9213043B2 (en) | 2012-05-15 | 2015-12-15 | Wellstat Diagnostics, Llc | Clinical diagnostic system including instrument and cartridge |
| US9075042B2 (en) | 2012-05-15 | 2015-07-07 | Wellstat Diagnostics, Llc | Diagnostic systems and cartridges |
| US9625465B2 (en) | 2012-05-15 | 2017-04-18 | Defined Diagnostics, Llc | Clinical diagnostic systems |
| US10545161B2 (en) | 2013-03-11 | 2020-01-28 | Cue Health Inc. | Systems and methods for detection and quantification of analytes |
| US9623409B2 (en) | 2013-03-11 | 2017-04-18 | Cue Inc. | Cartridges, kits, and methods for enhanced mixing for detection and quantification of analytes |
| CN112782393B (zh) | 2013-03-11 | 2024-11-19 | 克忧健康公司 | 用于检测和量化分析物的系统和方法 |
| USD745423S1 (en) | 2014-05-12 | 2015-12-15 | Cue Inc. | Automated analyzer test cartridge and sample collection device for analyte detection |
| US11009479B2 (en) * | 2014-05-27 | 2021-05-18 | Case Western Reserve University | Systems and methods for the detection of HbA1c |
| US10883956B2 (en) * | 2014-05-27 | 2021-01-05 | Case Western Reserve University | Electrochemical sensor for analyte detection |
| JP2016061769A (ja) * | 2014-09-22 | 2016-04-25 | 株式会社東芝 | 塩基配列検出チップ |
| JP6931035B2 (ja) * | 2014-09-22 | 2021-09-01 | キヤノンメディカルシステムズ株式会社 | 塩基配列検出チップ |
| CN107075433A (zh) * | 2014-09-22 | 2017-08-18 | 东芝医疗系统株式会社 | 核酸检查装置 |
| JP6927879B2 (ja) | 2015-01-14 | 2021-09-01 | ピクセル メディカル テクノロジーズ リミテッド | 試料流体分析用の使い捨てカートリッジ |
| AU2016243036B2 (en) | 2015-04-03 | 2022-02-17 | Abbott Laboratories | Devices and methods for sample analysis |
| WO2016161400A1 (en) * | 2015-04-03 | 2016-10-06 | Abbott Laboratories | Devices and methods for sample analysis |
| EP3325153B1 (en) | 2015-07-17 | 2020-03-18 | Cue Health Inc. | Sample analysis cartridge |
| CN105929153B (zh) * | 2016-04-26 | 2017-08-25 | 哈尔滨工业大学(威海) | 一种黄曲霉毒素b1金纳米井阵列免疫电极的制备方法 |
| US11237161B2 (en) | 2017-01-25 | 2022-02-01 | Cue Health Inc. | Systems and methods for enhanced detection and quantification of analytes |
| CN107045068A (zh) * | 2017-04-14 | 2017-08-15 | 刘锦 | 基于微流控纸芯片的便携式生理指标检测仪及其检测方法 |
| CN111323578B (zh) * | 2020-02-28 | 2023-11-03 | 京东方科技集团股份有限公司 | 一种微流控结构、微流控芯片及检测方法 |
| CN112326750B (zh) * | 2020-11-06 | 2023-07-11 | 吉林医药学院 | 一种基于微流控方法的甲型流感病毒检测装置与检测方法 |
| US20240295524A1 (en) * | 2021-08-31 | 2024-09-05 | Virginia Commonwealth University | Self-calibrated electrochemical sensors |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6673533B1 (en) * | 1995-03-10 | 2004-01-06 | Meso Scale Technologies, Llc. | Multi-array multi-specific electrochemiluminescence testing |
| WO2006045628A1 (en) * | 2004-10-28 | 2006-05-04 | École Polytechnique Fédérale de Lausanne | Adsorption monitoring device |
| CN101098956A (zh) * | 2002-12-26 | 2008-01-02 | 梅索磅秤技术有限公司 | 检定盒及其使用方法 |
| WO2011131795A1 (en) * | 2010-04-23 | 2011-10-27 | Celoxio Ab | Microfluidic systems with electronic wettability switches |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5399256A (en) * | 1994-01-07 | 1995-03-21 | Bioanalytical Systems, Inc. | Electrochemical detector cell |
| JPH09101283A (ja) * | 1995-10-03 | 1997-04-15 | Nippon Telegr & Teleph Corp <Ntt> | 電気化学検出器およびその製造方法 |
| US6942771B1 (en) | 1999-04-21 | 2005-09-13 | Clinical Micro Sensors, Inc. | Microfluidic systems in the electrochemical detection of target analytes |
| US20060228723A1 (en) * | 2002-01-16 | 2006-10-12 | Keith Bradley | System and method for electronic sensing of biomolecules |
| US7419821B2 (en) | 2002-03-05 | 2008-09-02 | I-Stat Corporation | Apparatus and methods for analyte measurement and immunoassay |
| EP1514097A1 (en) * | 2002-06-19 | 2005-03-16 | Becton, Dickinson and Company | Microfabricated sensor arrays |
| JP4597091B2 (ja) * | 2006-05-24 | 2010-12-15 | 株式会社日立ハイテクノロジーズ | 生化学分析装置及びそれに用いる検査カートリッジ |
| JP2009002939A (ja) * | 2007-05-18 | 2009-01-08 | Mitsubishi Kagaku Iatron Inc | アンペロメトリック型バイオセンサ |
| JP5026873B2 (ja) * | 2007-07-04 | 2012-09-19 | 株式会社船井電機新応用技術研究所 | 酵素電極、酵素電極の製造方法及び酵素センサ |
| JP2009216516A (ja) * | 2008-03-10 | 2009-09-24 | Sumitomo Electric Ind Ltd | バイオセンサチップおよびその製造方法 |
| EP2261648B1 (en) * | 2008-03-17 | 2014-05-21 | Mitsubishi Chemical Medience Corporation | Electric analysis method |
| GB0815472D0 (en) | 2008-08-22 | 2008-10-01 | Iti Scotland Ltd | Microfluidic system |
| JP2010156605A (ja) * | 2008-12-26 | 2010-07-15 | Mitsubishi Chemical Medience Corp | 電気的分析方法 |
| US8808519B2 (en) * | 2011-12-14 | 2014-08-19 | Hamilton Sundstrand Space Systems International | Microfluidic device |
-
2012
- 2012-03-13 US US14/384,538 patent/US20150047978A1/en not_active Abandoned
- 2012-03-13 CN CN201280071882.XA patent/CN104203808B/zh not_active Expired - Fee Related
- 2012-03-13 EP EP12717851.5A patent/EP2825501A1/en not_active Withdrawn
- 2012-03-13 WO PCT/IB2012/051170 patent/WO2013136115A1/en not_active Ceased
- 2012-03-13 IN IN8308DEN2014 patent/IN2014DN08308A/en unknown
- 2012-03-13 JP JP2014561524A patent/JP6013519B2/ja not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6673533B1 (en) * | 1995-03-10 | 2004-01-06 | Meso Scale Technologies, Llc. | Multi-array multi-specific electrochemiluminescence testing |
| CN101098956A (zh) * | 2002-12-26 | 2008-01-02 | 梅索磅秤技术有限公司 | 检定盒及其使用方法 |
| WO2006045628A1 (en) * | 2004-10-28 | 2006-05-04 | École Polytechnique Fédérale de Lausanne | Adsorption monitoring device |
| WO2011131795A1 (en) * | 2010-04-23 | 2011-10-27 | Celoxio Ab | Microfluidic systems with electronic wettability switches |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2825501A1 (en) | 2015-01-21 |
| CN104203808A (zh) | 2014-12-10 |
| US20150047978A1 (en) | 2015-02-19 |
| WO2013136115A1 (en) | 2013-09-19 |
| IN2014DN08308A (enExample) | 2015-05-15 |
| JP2015510136A (ja) | 2015-04-02 |
| JP6013519B2 (ja) | 2016-10-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| ASS | Succession or assignment of patent right |
Owner name: DESAI DIAGNOSTICS INDIA PTE LTD. Free format text: FORMER OWNER: PIRAMAL ENTERPRISES LTD. Effective date: 20141126 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20141126 Address after: Mumbai Applicant after: DESAY diagnostics India Pte Ltd Address before: Mumbai Applicant before: Piramal Life Sciences Ltd. |
|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170609 Termination date: 20180313 |