CN104203256B - 用于引产的包含硫酸化的葡糖胺聚糖的联合治疗 - Google Patents

用于引产的包含硫酸化的葡糖胺聚糖的联合治疗 Download PDF

Info

Publication number
CN104203256B
CN104203256B CN201380016550.6A CN201380016550A CN104203256B CN 104203256 B CN104203256 B CN 104203256B CN 201380016550 A CN201380016550 A CN 201380016550A CN 104203256 B CN104203256 B CN 104203256B
Authority
CN
China
Prior art keywords
chemically modified
heparin
heparan sulfate
solution
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201380016550.6A
Other languages
English (en)
Chinese (zh)
Other versions
CN104203256A (zh
Inventor
G·埃克曼-奥德贝格
A·M·马尔姆斯特伦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Di Lefang LLC
Original Assignee
Di Lefang LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Di Lefang LLC filed Critical Di Lefang LLC
Publication of CN104203256A publication Critical patent/CN104203256A/zh
Application granted granted Critical
Publication of CN104203256B publication Critical patent/CN104203256B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201380016550.6A 2012-03-26 2013-03-25 用于引产的包含硫酸化的葡糖胺聚糖的联合治疗 Active CN104203256B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261615398P 2012-03-26 2012-03-26
US61/615,398 2012-03-26
PCT/SE2013/050332 WO2013147689A1 (en) 2012-03-26 2013-03-25 Combination treatment comprising sulphated glycosaminoglycans for inducing labor

Publications (2)

Publication Number Publication Date
CN104203256A CN104203256A (zh) 2014-12-10
CN104203256B true CN104203256B (zh) 2017-11-24

Family

ID=49260783

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380016550.6A Active CN104203256B (zh) 2012-03-26 2013-03-25 用于引产的包含硫酸化的葡糖胺聚糖的联合治疗

Country Status (15)

Country Link
US (1) US20150045322A1 (enExample)
EP (1) EP2830635A4 (enExample)
JP (1) JP6234989B2 (enExample)
CN (1) CN104203256B (enExample)
AU (1) AU2013240597A1 (enExample)
CA (1) CA2868444A1 (enExample)
HK (1) HK1203369A1 (enExample)
IL (1) IL234689A0 (enExample)
MX (1) MX2014011505A (enExample)
MY (1) MY175743A (enExample)
RU (1) RU2014143017A (enExample)
SG (1) SG11201406119WA (enExample)
UA (1) UA117908C2 (enExample)
WO (1) WO2013147689A1 (enExample)
ZA (1) ZA201406901B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013095215A1 (en) 2011-12-19 2013-06-27 Dilaforette Ab Low anticoagulant heparins
SMT201800143T1 (it) 2011-12-19 2018-05-02 Dilafor Ab Glicosaminoglicani non anticoagulanti comprendenti un'unita ripetitiva di disaccaridi e loro uso medico
CA2868403A1 (en) * 2012-05-08 2013-11-14 Dilafor Ab Treatment of postpartum haemorrhage with chemically modified heparin or heparan sulphate and a uterotonic agent
KR20220142508A (ko) * 2020-02-17 2022-10-21 딜라포 아베 자간전증 치료용 타폭시파린
CA3255831A1 (en) 2022-05-03 2023-11-09 Dilafor Ab NEW MEDICAL USE OF TAFOXIPARIN
EP4272749A1 (en) 2022-05-03 2023-11-08 Dilafor AB New medical use of tafoxiparin

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4990502A (en) * 1987-04-16 1991-02-05 Sanofi, S.A. Low molecular weight heparins of regular structure, their preparation and their biological uses.
CN1186502A (zh) * 1995-03-31 1998-07-01 汉弥尔登市立医院研究发展股份有限公司 抑制血栓形成的组合物和方法
CN1612741A (zh) * 2002-01-02 2005-05-04 迪拉富尔公司 硫酸化葡糖胺聚糖在建立妇女有效分娩中的用途
CN104144950A (zh) * 2011-12-19 2014-11-12 迪乐方有限责任公司 含有重复的二糖单元的非抗凝的葡糖胺聚糖及其医药用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5993810A (en) * 1996-03-15 1999-11-30 Lebovitz; Shamir Israel Method of softening or ripening the cervix of a female mammal using collagenase
US8445436B2 (en) * 2007-12-03 2013-05-21 Florida State University Research Foundation, Inc. Oxytocin and melatonin compositions and associated methods for inducing labor
KR20140097380A (ko) * 2011-11-28 2014-08-06 코닝 인코포레이티드 평면 투명 시트를 사용한，강력한 광학 터치 스크린 시스템 및 방법

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4990502A (en) * 1987-04-16 1991-02-05 Sanofi, S.A. Low molecular weight heparins of regular structure, their preparation and their biological uses.
CN1186502A (zh) * 1995-03-31 1998-07-01 汉弥尔登市立医院研究发展股份有限公司 抑制血栓形成的组合物和方法
CN1612741A (zh) * 2002-01-02 2005-05-04 迪拉富尔公司 硫酸化葡糖胺聚糖在建立妇女有效分娩中的用途
CN104144950A (zh) * 2011-12-19 2014-11-12 迪乐方有限责任公司 含有重复的二糖单元的非抗凝的葡糖胺聚糖及其医药用途

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Low anticoagulant Heparin Disrupts Plasmodium falciparum Rosettes in Fresh Clinical Isolates;Anna M.Leitgeb;《The American Society of Tropical Medicine and Hygiene》;20110331;第84卷(第3期);391 *

Also Published As

Publication number Publication date
WO2013147689A1 (en) 2013-10-03
US20150045322A1 (en) 2015-02-12
SG11201406119WA (en) 2014-11-27
MY175743A (en) 2020-07-07
AU2013240597A1 (en) 2014-10-16
IL234689A0 (en) 2014-11-30
ZA201406901B (en) 2017-09-27
HK1203369A1 (en) 2015-10-30
CA2868444A1 (en) 2013-10-03
JP6234989B2 (ja) 2017-11-22
EP2830635A4 (en) 2016-03-16
UA117908C2 (uk) 2018-10-25
JP2015511664A (ja) 2015-04-20
EP2830635A1 (en) 2015-02-04
MX2014011505A (es) 2014-12-05
CN104203256A (zh) 2014-12-10
RU2014143017A (ru) 2016-05-20

Similar Documents

Publication Publication Date Title
CN104244957B (zh) 用于治疗分娩停止的方法
US8524688B2 (en) Use of sulfated glycosaminoglycans for establishing effective labor in women
CN104203256B (zh) 用于引产的包含硫酸化的葡糖胺聚糖的联合治疗
CN104284667A (zh) 采用化学修饰的肝素或硫酸乙酰肝素和子宫收缩剂的产后出血的治疗
HK1076389B (en) Use of sulfated glycosaminoglycans for the manufacture of a pharmaceutical preparation for the prevention and treatment of slow progress of term labor

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant