CN104189411A - Traditional Chinese medicine preparation for improving sleeping quality - Google Patents
Traditional Chinese medicine preparation for improving sleeping quality Download PDFInfo
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- CN104189411A CN104189411A CN201410416898.0A CN201410416898A CN104189411A CN 104189411 A CN104189411 A CN 104189411A CN 201410416898 A CN201410416898 A CN 201410416898A CN 104189411 A CN104189411 A CN 104189411A
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Abstract
The invention provides a traditional Chinese medicine preparation for improving sleeping quality. The preparation can be various oral preparations prepared by using the following raw medicinal materials: rhizoma anemarrhenae, polygala tenuifolia, semen ziziphi spinosae, acanthopanax root and poria cocos according to a pharmaceutical convention process and auxiliaries. The five medicinal materials are compatible to synergize the effects of each medicinal material so as to play roles in nourishing yin and clearing heat, moistening dryness and tranquilizing, relieving restlessness and promoting sleeping, so that the sleeping quality can be improved on the premise of searching for the primary cause of disease in treatment and radically solidifying to treat root causes. Clinical tests prove that the traditional Chinese medicine preparation has remarkable effects for regulating and improving insomnia, less sleep or difficult sleep caused by various reasons, and is capable of effectively improving the sleeping quality of tested persons.
Description
Technical field
The invention belongs to Chinese medicine health-care field, relate to a kind of for improving the Chinese medicine preparation of sleep quality.
Background technology
Ancient Chinese medicine health preserving is one of China's traditional culture marrow of extensive knowledge and profound scholarship, and it widely collects many families elite, integrates each region of various nationalities people's illness prevention and fitness wisdom, has brought into play very important effect in the process of human body anti-disease, anti-aging.In traditional Chinese medical science health preserving in ancient times, attach great importance to sleep health preserving art, ancients have saying of " not looking for celestial being side and look for the side of sleeping ".< < Huang di's Canon of Medicine > > uncoiling is mentioned in innocent opinion > > first piece of < < ancient times, " ... daily life often has; avoiding overstrain ... and most eventually its natural life-span ", it serves to show the importance of sleep.
In people's life course, nearly 1/3 time is spent in sleep.Sleep health preserving, is according to negative and positive Changing Pattern, adopts reasonable sleep method and measure, guarantees sufficient and to recover as early as possible organism fatigue, keep abundant energy the suitable length of one's sleep, thereby reaching diseases prevention is healthy and strong, the object of life lengthening.The puzzled opinion of < < Ling Shu Miraculous Pivot or Divine Axis > > says: " yang-energy is to the greatest extent sleeping; cloudy gas is awake to the greatest extent ", < < Ling Shu Miraculous Pivot or Divine Axis mouth asks > that > says: " the to the greatest extent cloudy arrogant blurring of vision of yang-energy; cloudy gas to the greatest extent yang-energy is contained awake ", therefore sleep is also the necessary stage in wane and wax of yin and yang alternately, that human body is in order to conform, the performance that keeps negative and positive self regulation balance is the assurance of safeguarding health so maintain ortho sleep.
Sleep the most suitable first sleeping eyes, after the heart of sleeping, the heart of first waking up, after catch the eye, and close nature, this is sleep health preserving Zhi Shang road.Sleep health preserving the most important thing is sleep quality, and will improve sleep quality, except the sleep health preserving method of necessary grasp science, is also necessary to study other more effectively Opsonizing method.
The product of current various hypnotic, lifting sleep quality is a feast for the eyes, but its effect is uneven, and has toxic and side effects in various degree, so its market value of research and development associated safety Reliable Products is huge.
Summary of the invention
The object of this invention is to provide a kind of for improving the Chinese medicine preparation of sleep quality.
Chinese medicine preparation of the present invention, take the Rhizoma Anemarrhenae, Radix Polygalae, Semen Ziziphi Spinosae, Radix Et Caulis Acanthopanacis Senticosi, Poria as raw material carries out prescription compatibility, the effect of each medicine is produced collaborative, plays altogether replenishing YIN and removing heat, moisturizes mind calming, the function of relieving restlessness sleeping, and then promote sleep quality.
The Rhizoma Anemarrhenae: bitter in the mouth, sweet, cold in nature; Return lung, stomach, kidney channel; Clearing away heat-fire, promotes the production of body fluid and moisturizes.The Rhizoma Anemarrhenae is made monarch drug, promotes the production of body fluid with yin nourishing, moisturizes to protect the moon, heat clearing away to pacify the moon, keep the moon keep quiet to sleep peacefully without tired, base oneself upon farsighted, treatment must aim at the pathogenesis of disease (moving difficult dormancy of sun, cloudy quiet sleeps peacefully).
Radix Polygalae: bitter in the mouth, pungent, warm in nature; GUIXIN, kidney, lung meridian; Calm the nerves, Fructus Alpiniae Oxyphyllae, eliminate the phlegm, subside a swelling.Radix Polygalae, as ministerial drug, is calmed the nerves and is made people quiet happy, and Fructus Alpiniae Oxyphyllae makes people god not busy, directly plays a role, and promotes sleep quality.
Semen Ziziphi Spinosae: sweet in the mouth, acid, property is flat; Return liver, gallbladder, heart channel; Tonifying liver, mind calming, arresting sweating, promote the production of body fluid.Radix Et Caulis Acanthopanacis Senticosi: acrid in the mouth, micro-hardship, warm in nature; Return spleen, kidney, heart channel; Replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization.Semen Ziziphi Spinosae, Radix Et Caulis Acanthopanacis Senticosi are adjuvant drug altogether, tonifying liver with mind calming, the kidney invigorating calming the nerves, relieving restlessness to be to set aside all worries, and assists a ruler in governing a country the monarch and his subjects, power reaches and promotes sleep quality object.
Poria: sweet in the mouth, light, property is flat; GUIXIN, lung, spleen, kidney channel; Promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.Poria, for making medicine, not only acts on upper, middle and lower three warmers, and can also, by supporting lung, spleen invigorating, kidney tonifying with mind calming, promote sleep quality.
The full side's five tastes of the present invention are played altogether replenishing YIN and removing heat, are moisturized mind calming, the function of relieving restlessness sleeping, with treatment must aim at the pathogenesis of disease, radically reform and improve sleep quality into prerequisite.
Each raw material of Chinese medicine preparation of the present invention carries out proportioning by following weight portion: Rhizoma Anemarrhenae 25-45 part, Radix Polygalae 20-30 part, Semen Ziziphi Spinosae 15-25 part, Radix Et Caulis Acanthopanacis Senticosi 15-25 part, Poria 1-10 part.
Optimum ratio: Rhizoma Anemarrhenae 28-35 part, Radix Polygalae 20-25 part, Semen Ziziphi Spinosae 18-20 part, Radix Et Caulis Acanthopanacis Senticosi 18-20 part, Poria 3-6 part.
Best proportioning: 30 parts of the Rhizoma Anemarrhenaes, 25 parts of Radix Polygalaes, 20 parts of Semen Ziziphi Spinosaes, 20 parts of Radix Et Caulis Acanthopanacis Senticosis, 5 parts, Poria.
Chinese medicine preparation of the present invention can be prepared into various oral preparations by the common process of pharmaceutics and adjuvant.As capsule, tablet, granule, powder, pill (comprising the watered pill, honeyed pill, dragee, soft gelatin capsule, enteric coated pill or drop pill) or oral liquid.
Be that medicine of the present invention is had a sleepless night for improving, difficult dormancy problem below, improve the clinical trial data of sleep quality.
1, study subject: medical fitness, poor sleeping quality or person's 100 examples that have sleep disorder, the age was at 18 ~ 60 years old.Be divided into matched group and tested group two groups, every group of 50 examples.
2, Therapeutic Method: tested group: capsule medicine of the present invention (stability maintenance capsule): specification 350mg/ grain * 80/bottle.Usage: each 3 sooner or later 3 months was 1 cycle.Matched group does not adopt Drug therapy.
3, criterion: adopt Pittsburg sleep quality index scale to amount to and divide, evaluation subjects observes the subjective sleep quality after one-period.Specifically see the following form.SQI total points scope is 0-2l, and score is higher, represents that sleep quality is poorer.
4, observed result: calculate SQI total points after observing one-period.Tested group of 50 routine marks all have varying strength to decline, and on average reduce by 12 minutes, and the highest reduction by 15 minutes, has no rise phenomenon.The average reduction by 1 minute of matched group 50 examples, the highest reduction by 4 minutes, the highest rising 3 minutes.
5, conclusion: the insomnia that Chinese medicine preparation of the present invention causes a variety of causes, difficult dormancy problem all have good adjusting and improvement effect, have effectively improved experimenter's sleep quality.
The specific embodiment
Below by specific embodiment, the prescription of medicine of the present invention and preparation thereof are described further.
The preparation of embodiment 1, capsule medicine
Proportioning raw materials: 30 parts of the Rhizoma Anemarrhenaes, 25 parts of Radix Polygalaes, 20 parts of Semen Ziziphi Spinosaes, 20 parts of Radix Et Caulis Acanthopanacis Senticosis, 5 parts, Poria;
Preparation technology: common process and the adjuvant of preparing capsule by pharmaceutics are prepared from.Specification: 350mg/ grain;
Usage and dosage: each 3 sooner or later 3 months was 1 cycle.
The preparation of embodiment 2, granules medicine
Proportioning raw materials: 25 parts of the Rhizoma Anemarrhenaes, 20 parts of Radix Polygalaes, 15 parts of Semen Ziziphi Spinosaes, 15 parts of Radix Et Caulis Acanthopanacis Senticosis, 1 part, Poria;
Preparation technology: common process and the adjuvant of preparing granule by pharmaceutics are prepared from.Specification: 5g/ bag.
Usage and dosage: each 5g of morning and evening 3 months was 1 cycle.
The preparation of embodiment 3, tablet medicine
Proportioning raw materials: 45 parts of the Rhizoma Anemarrhenaes, 30 parts of Radix Polygalaes, 25 parts of Semen Ziziphi Spinosaes, 25 parts of Radix Et Caulis Acanthopanacis Senticosis, 10 parts, Poria;
Preparation technology: common process and the adjuvant of preparing tablet by pharmaceutics are prepared from.Specification: 1.0g/ grain;
Usage and dosage: each 1g of morning and evening 3 months was 1 cycle.
The preparation of embodiment 4, pill medicine
Proportioning raw materials: 35 parts of the Rhizoma Anemarrhenaes, 25 parts of Radix Polygalaes, 20 parts of Semen Ziziphi Spinosaes, 20 parts of Radix Et Caulis Acanthopanacis Senticosis, 6 parts, Poria;
Preparation technology: common process and the adjuvant of preparing pill by pharmaceutics are prepared from.Specification: 0.25g grain/;
Usage and dosage: each 1.0g of morning and evening 3 months was 1 cycle.
The preparation of embodiment 5, oral medicine liquid of the present invention
Proportioning raw materials: 28 parts of the Rhizoma Anemarrhenaes, 20 parts of Radix Polygalaes, 18 parts of Semen Ziziphi Spinosaes, 18 parts of Radix Et Caulis Acanthopanacis Senticosis, 3 parts, Poria;
Preparation technology: common process and the adjuvant of preparing oral liquid by pharmaceutics are prepared from.Specification: 10ml/ bottle;
Usage and dosage: each 10ml of morning and evening 3 months was 1 cycle.
In the various embodiments described above, each proportioning raw materials is all in weight portion.
Claims (5)
1. for improving the Chinese medicine preparation of sleep quality, be that to take the Rhizoma Anemarrhenae, Radix Polygalae, Semen Ziziphi Spinosae, Radix Et Caulis Acanthopanacis Senticosi, Poria be crude drug, by the common process of pharmaceutics and adjuvant, be prepared into various oral preparations.
2. as claimed in claim 1 for improving the Chinese medicine preparation of sleep quality, it is characterized in that: described each crude drug carries out proportioning by following weight portion: Rhizoma Anemarrhenae 25-45 part, Radix Polygalae 20-30 part, Semen Ziziphi Spinosae 15-25 part, Radix Et Caulis Acanthopanacis Senticosi 15-25 part, Poria 1-10 part.
3. as claimed in claim 1 for improving the Chinese medicine preparation of sleep quality, it is characterized in that: described each crude drug carries out proportioning by following weight portion: Rhizoma Anemarrhenae 28-35 part, Radix Polygalae 20-25 part, Semen Ziziphi Spinosae 18-20 part, Radix Et Caulis Acanthopanacis Senticosi 18-20 part, Poria 3-6 part.
4. as claimed in claim 1 for improving the Chinese medicine preparation of sleep quality, it is characterized in that: described each crude drug carries out proportioning by following weight portion: 30 parts of the Rhizoma Anemarrhenaes, 25 parts of Radix Polygalaes, 20 parts of Semen Ziziphi Spinosaes, 20 parts of Radix Et Caulis Acanthopanacis Senticosis, 5 parts, Poria.
5. as claimed in claim 1 for improving the Chinese medicine preparation of sleep quality, it is characterized in that: described oral preparations is capsule, tablet, granule, pill or oral liquid.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410416898.0A CN104189411A (en) | 2014-08-22 | 2014-08-22 | Traditional Chinese medicine preparation for improving sleeping quality |
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| CN201410416898.0A CN104189411A (en) | 2014-08-22 | 2014-08-22 | Traditional Chinese medicine preparation for improving sleeping quality |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101474347A (en) * | 2007-12-31 | 2009-07-08 | 天津中新药业研究中心 | Oral solid preparation for promoting sleep and preparation method thereof |
| CN102657715A (en) * | 2012-05-17 | 2012-09-12 | 双飞人制药（中国）有限公司 | Drug combination with function of improving sleep |
| JP2013053144A (en) * | 2011-08-09 | 2013-03-21 | Daiichi Sankyo Healthcare Co Ltd | Sedative composition |
-
2014
- 2014-08-22 CN CN201410416898.0A patent/CN104189411A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101474347A (en) * | 2007-12-31 | 2009-07-08 | 天津中新药业研究中心 | Oral solid preparation for promoting sleep and preparation method thereof |
| JP2013053144A (en) * | 2011-08-09 | 2013-03-21 | Daiichi Sankyo Healthcare Co Ltd | Sedative composition |
| CN102657715A (en) * | 2012-05-17 | 2012-09-12 | 双飞人制药（中国）有限公司 | Drug combination with function of improving sleep |
Non-Patent Citations (2)
| Title |
|---|
| 刘莉等: "《中草药识别与应用 上》", 30 April 2012, 中国医药科技出版社 * |
| 远田裕政: "酸枣仁汤治疗失眠两例", 《南京中医学院学报》 * |
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Application publication date: 20141210 |