CN104170833A - Composition containing oligosaccharide and polyhexamethylene biguanidine or salt of polyhexamethylene biguanidine - Google Patents
Composition containing oligosaccharide and polyhexamethylene biguanidine or salt of polyhexamethylene biguanidine Download PDFInfo
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- CN104170833A CN104170833A CN201410441319.8A CN201410441319A CN104170833A CN 104170833 A CN104170833 A CN 104170833A CN 201410441319 A CN201410441319 A CN 201410441319A CN 104170833 A CN104170833 A CN 104170833A
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- China
- Prior art keywords
- composition
- hexamethylene biguanide
- poly hexamethylene
- chitosan oligosaccharide
- polyhexamethylene biguanidine
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- 239000000203 mixture Substances 0.000 title claims abstract description 82
- 229920001542 oligosaccharide Polymers 0.000 title claims abstract description 27
- 150000002482 oligosaccharides Chemical class 0.000 title claims abstract description 27
- 150000003839 salts Chemical class 0.000 title claims abstract description 17
- -1 polyhexamethylene Polymers 0.000 title abstract description 13
- ZILVNHNSYBNLSZ-UHFFFAOYSA-N 2-(diaminomethylideneamino)guanidine Chemical compound NC(N)=NNC(N)=N ZILVNHNSYBNLSZ-UHFFFAOYSA-N 0.000 title abstract 8
- RQFQJYYMBWVMQG-IXDPLRRUSA-N chitotriose Chemical compound O[C@@H]1[C@@H](N)[C@H](O)O[C@H](CO)[C@H]1O[C@H]1[C@H](N)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)N)[C@@H](CO)O1 RQFQJYYMBWVMQG-IXDPLRRUSA-N 0.000 claims abstract description 60
- 201000010099 disease Diseases 0.000 claims abstract description 43
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 43
- 229910019142 PO4 Inorganic materials 0.000 claims abstract description 18
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims abstract description 18
- 239000010452 phosphate Substances 0.000 claims abstract description 18
- 240000007594 Oryza sativa Species 0.000 claims abstract description 16
- 235000007164 Oryza sativa Nutrition 0.000 claims abstract description 16
- 235000009566 rice Nutrition 0.000 claims abstract description 16
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 claims abstract description 14
- 241000196324 Embryophyta Species 0.000 claims abstract description 14
- 235000002566 Capsicum Nutrition 0.000 claims abstract description 13
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims abstract description 13
- 241000700605 Viruses Species 0.000 claims abstract description 13
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims abstract description 12
- 230000001580 bacterial effect Effects 0.000 claims abstract description 11
- 241000207199 Citrus Species 0.000 claims abstract description 10
- 235000020971 citrus fruits Nutrition 0.000 claims abstract description 10
- 239000000375 suspending agent Substances 0.000 claims abstract description 9
- 239000004562 water dispersible granule Substances 0.000 claims abstract description 9
- 239000006002 Pepper Substances 0.000 claims abstract description 8
- 235000016761 Piper aduncum Nutrition 0.000 claims abstract description 8
- 235000017804 Piper guineense Nutrition 0.000 claims abstract description 8
- 235000008184 Piper nigrum Nutrition 0.000 claims abstract description 8
- 239000000839 emulsion Substances 0.000 claims abstract description 5
- 239000004530 micro-emulsion Substances 0.000 claims abstract description 5
- 241000894006 Bacteria Species 0.000 claims abstract description 3
- 241000233866 Fungi Species 0.000 claims abstract description 3
- 244000241235 Citrullus lanatus Species 0.000 claims abstract 4
- 244000203593 Piper nigrum Species 0.000 claims abstract 2
- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Polymers CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 claims description 76
- 229920002413 Polyhexanide Polymers 0.000 claims description 76
- 229910021653 sulphate ion Inorganic materials 0.000 claims description 11
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims description 8
- 239000000843 powder Substances 0.000 claims description 8
- 238000009736 wetting Methods 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 6
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims description 5
- 240000008574 Capsicum frutescens Species 0.000 claims description 5
- MIWVBVPUEOHJFV-UHFFFAOYSA-N [amino(azaniumylidene)methyl]-(diaminomethylidene)azanium;sulfate Chemical compound OS(O)(=O)=O.NC(N)=NC(N)=N MIWVBVPUEOHJFV-UHFFFAOYSA-N 0.000 claims description 5
- 239000001390 capsicum minimum Substances 0.000 claims description 5
- AVWOEAVWVDLXMA-UHFFFAOYSA-N 1-(diaminomethylidene)guanidine;nitric acid Chemical compound O[N+]([O-])=O.NC(N)=NC(N)=N AVWOEAVWVDLXMA-UHFFFAOYSA-N 0.000 claims description 4
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims description 4
- 241000675108 Citrus tangerina Species 0.000 claims description 4
- 238000005507 spraying Methods 0.000 claims description 3
- 240000008067 Cucumis sativus Species 0.000 claims description 2
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 claims description 2
- 241000220225 Malus Species 0.000 claims description 2
- 235000011430 Malus pumila Nutrition 0.000 claims description 2
- 235000015103 Malus silvestris Nutrition 0.000 claims description 2
- 241000220324 Pyrus Species 0.000 claims description 2
- 235000021307 Triticum Nutrition 0.000 claims description 2
- 244000098338 Triticum aestivum Species 0.000 claims description 2
- 235000009754 Vitis X bourquina Nutrition 0.000 claims description 2
- 235000012333 Vitis X labruscana Nutrition 0.000 claims description 2
- 240000006365 Vitis vinifera Species 0.000 claims description 2
- 235000014787 Vitis vinifera Nutrition 0.000 claims description 2
- 235000021017 pears Nutrition 0.000 claims description 2
- 239000005764 Dithianon Substances 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- PYZSVQVRHDXQSL-UHFFFAOYSA-N dithianon Chemical compound S1C(C#N)=C(C#N)SC2=C1C(=O)C1=CC=CC=C1C2=O PYZSVQVRHDXQSL-UHFFFAOYSA-N 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 abstract description 6
- UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 abstract 1
- 241000223218 Fusarium Species 0.000 abstract 1
- AKGZDINYLOSBTE-UHFFFAOYSA-N [(e)-n'-(diaminomethylideneamino)carbamimidoyl]azanium;chloride Chemical compound Cl.NC(=N)NN=C(N)N AKGZDINYLOSBTE-UHFFFAOYSA-N 0.000 abstract 1
- 239000004563 wettable powder Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 37
- 230000003449 preventive effect Effects 0.000 description 18
- 238000002360 preparation method Methods 0.000 description 13
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- 239000003814 drug Substances 0.000 description 10
- 238000012360 testing method Methods 0.000 description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 241000722363 Piper Species 0.000 description 8
- 230000002195 synergetic effect Effects 0.000 description 7
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 238000011160 research Methods 0.000 description 6
- 230000000844 anti-bacterial effect Effects 0.000 description 5
- OMOVVBIIQSXZSZ-UHFFFAOYSA-N [6-(4-acetyloxy-5,9a-dimethyl-2,7-dioxo-4,5a,6,9-tetrahydro-3h-pyrano[3,4-b]oxepin-5-yl)-5-formyloxy-3-(furan-3-yl)-3a-methyl-7-methylidene-1a,2,3,4,5,6-hexahydroindeno[1,7a-b]oxiren-4-yl] 2-hydroxy-3-methylpentanoate Chemical compound CC12C(OC(=O)C(O)C(C)CC)C(OC=O)C(C3(C)C(CC(=O)OC4(C)COC(=O)CC43)OC(C)=O)C(=C)C32OC3CC1C=1C=COC=1 OMOVVBIIQSXZSZ-UHFFFAOYSA-N 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 244000052769 pathogen Species 0.000 description 4
- 230000001717 pathogenic effect Effects 0.000 description 4
- 239000007921 spray Substances 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- DUIOKRXOKLLURE-UHFFFAOYSA-N 2-octylphenol Chemical compound CCCCCCCCC1=CC=CC=C1O DUIOKRXOKLLURE-UHFFFAOYSA-N 0.000 description 3
- 244000215068 Acacia senegal Species 0.000 description 3
- 239000005995 Aluminium silicate Substances 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- 229920000084 Gum arabic Polymers 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 3
- 235000010489 acacia gum Nutrition 0.000 description 3
- 239000000205 acacia gum Substances 0.000 description 3
- 235000012211 aluminium silicate Nutrition 0.000 description 3
- 229940077388 benzenesulfonate Drugs 0.000 description 3
- 229920005551 calcium lignosulfonate Polymers 0.000 description 3
- RYAGRZNBULDMBW-UHFFFAOYSA-L calcium;3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Ca+2].COC1=CC=CC(CC(CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O RYAGRZNBULDMBW-UHFFFAOYSA-L 0.000 description 3
- 239000002131 composite material Substances 0.000 description 3
- 238000001816 cooling Methods 0.000 description 3
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 3
- 230000005669 field effect Effects 0.000 description 3
- 235000011187 glycerol Nutrition 0.000 description 3
- 238000005469 granulation Methods 0.000 description 3
- 230000003179 granulation Effects 0.000 description 3
- 238000000227 grinding Methods 0.000 description 3
- 125000004836 hexamethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[*:1] 0.000 description 3
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 3
- 229920000151 polyglycol Polymers 0.000 description 3
- 239000010695 polyglycol Substances 0.000 description 3
- 238000012216 screening Methods 0.000 description 3
- 239000011734 sodium Substances 0.000 description 3
- 229910052708 sodium Inorganic materials 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000007123 defense Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000000575 pesticide Substances 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 description 2
- RNMDNPCBIKJCQP-UHFFFAOYSA-N 5-nonyl-7-oxabicyclo[4.1.0]hepta-1,3,5-trien-2-ol Chemical compound C(CCCCCCCC)C1=C2C(=C(C=C1)O)O2 RNMDNPCBIKJCQP-UHFFFAOYSA-N 0.000 description 1
- FRXSZNDVFUDTIR-UHFFFAOYSA-N 6-methoxy-1,2,3,4-tetrahydroquinoline Chemical compound N1CCCC2=CC(OC)=CC=C21 FRXSZNDVFUDTIR-UHFFFAOYSA-N 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 241000219112 Cucumis Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- 229920001732 Lignosulfonate Polymers 0.000 description 1
- 229910002651 NO3 Inorganic materials 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- QYKIQEUNHZKYBP-UHFFFAOYSA-N Vinyl ether Chemical compound C=COC=C QYKIQEUNHZKYBP-UHFFFAOYSA-N 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- LVSNBJOSPVTNNS-UHFFFAOYSA-N [O].C1=CC=CC=C1.C(CCCCCCCC)C1=C(C=CC=C1)O Chemical compound [O].C1=CC=CC=C1.C(CCCCCCCC)C1=C(C=CC=C1)O LVSNBJOSPVTNNS-UHFFFAOYSA-N 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 239000002518 antifoaming agent Substances 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- GQBJGCRYICJRII-UHFFFAOYSA-N formaldehyde 2-(2-phenylethyl)phenol Chemical compound C=O.C1(=CC=CC=C1)CCC1=C(C=CC=C1)O GQBJGCRYICJRII-UHFFFAOYSA-N 0.000 description 1
- 230000002070 germicidal effect Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 150000002596 lactones Chemical class 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 229920001568 phenolic resin Polymers 0.000 description 1
- 210000002706 plastid Anatomy 0.000 description 1
- 229920000056 polyoxyethylene ether Polymers 0.000 description 1
- 229940051841 polyoxyethylene ether Drugs 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229920001289 polyvinyl ether Polymers 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 238000009331 sowing Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention belongs to the field of plant protection and relates to a composition containing oligosaccharide and polyhexamethylene biguanidine or salt of polyhexamethylene biguanidine, wherein the oligosaccharide is one or more of chitosan oligosaccharide, chitosan oligosaccharide hydrochloride, chitosan oligosaccharide sulfate and chitosan oligosaccharide phosphate, the mass ratio of oligosaccharide to polyhexamethylene biguanidine or the salt of polyhexamethylene biguanidine is 1:20 to 21:1, and polyhexamethylene biguanidine hydrochloride is one of polyhexamethylene biguanidine hydrochloric acid and polyhexamethylene biguanidine phosphate. The composition can be prepared into an aqueous agent, a microemulsion, an aqueous emulsion, a suspending agent, a water dispersible granule and wettable powder and can be used for preventing and curing various diseases caused by fungi, bacteria and virus, especially used for preventing and curing watermelon fusarium wilt, citrus bacterial canker, rice bakanae diseases, pepper virus diseases and the like.
Description
Technical field
The invention belongs to plant protection field, be specifically related to a kind of agriculturally useful compositions containing oligosaccharides and poly hexamethylene biguanide or its salt, composition is mainly used in preventing and treating the disease of the various plants such as melon and fruit, vegetables, grain and cotton.
Background technology
Come from the compound that organism and biodegradability are good and caused pesticide research person's very big interest, in these compounds, have no side effect, the chitosan oligosaccharide of easily biological-degradable has very large potentiality, becomes the new medicament of controlling disease.Chitosan oligosaccharide is as the important plant inducing anti-disease agent of a class, derive from the research of the oligosaccharide of plant, research shows, chitosan oligosaccharide and salt thereof resist pathogen corrode process in, can induction excite plant to produce a series of defense reaction, these defense reaction synergies stop propagation and the invasion of pathogen, reach the effect of preventing and curing diseases.
Poly hexamethylene biguanide is a kind of broad spectrum antimicrobicide efficiently, colorless and odorless, and consumption is low, wide spectrum low toxicity, speed of action is fast, and foam volume is low, after using, forms for a long time antibacterial, nontoxic of one deck cation at article surface.Due to poly hexamethylene biguanide as cationic germicide in agriculture field application, can be adsorbed in rapidly bacterial cell surface, attack fast and destroy cell membrane, suppress film lactones plastid synthetic, cause thalline apoptosis, thereby reach best sterilization and disinfection effect, pathogenic bacteria, virus are pulled the grass up by its roots.
For delaying the control efficiency of the drug-fast generation of germ and raising medicament, be necessary to carry out rational composition research.Also not about the report of oligosaccharides and poly hexamethylene biguanide or its salt composition research, inventor, by the research of the composite effect to bactericidal composition, has found some beyond thought effects at present.
Summary of the invention
The object of the present invention is to provide a kind of composition containing oligosaccharides and poly hexamethylene biguanide or its salt with synergistic effect, the present invention realizes by following measures.
The invention provides a kind of composition containing oligosaccharides and poly hexamethylene biguanide or its salt, it is characterized in that in said composition, oligosaccharides is one or more in chitosan oligosaccharide, chitosan oligosaccharide hydrochloride, chitosan oligosaccharide sulphate, chitosan oligosaccharide phosphate, the ratio of quality and the number of copies of oligosaccharides and poly hexamethylene biguanide or its salt is 1:20-20:1, preferably, ratio of quality and the number of copies is 1:10-10:1.
In above-mentioned bactericidal composition, cosmocil stearate is the one in hexamethylene, poly hexamethylene biguanide phosphate, poly hexamethylene biguanide nitrate, poly hexamethylene biguanide carbonate, poly hexamethylene biguanide sulphate, poly hexamethylene biguanide stearate, poly hexamethylene biguanide acetate.
In above-mentioned bactericidal composition, the quality sum of oligosaccharides and poly hexamethylene biguanide or its salt accounts for the 1%-80% of composition gross mass.
Above-mentioned composition of the present invention can be made into aqua, microemulsion, aqueous emulsion, suspending agent, water dispersible granules, wetting powder etc.
The present invention also provides the application method containing the composition of oligosaccharides and poly hexamethylene biguanide or its salt, for the plant seed dressing to control, spraying, filling root etc.
The application method of above-mentioned composition of the present invention, described plant is watermelon, oranges and tangerines, paddy rice, capsicum, apple, pears, grape, lichee, cucumber, turfgrass, rape, wheat, flowers etc., preferred, described plant is watermelon, oranges and tangerines, paddy rice, capsicum.
The present invention also provides and has contained the composition of oligosaccharides and poly hexamethylene biguanide or its salt for the purposes of controlling plant diseases, the disease of suitable control is the multiple diseases that fungi, bacterium and virus cause, preferably, disease is watermelon blight, citrus bacterial canker disease, bakanae disease of rice, pepper virus disease etc.
Beneficial effect of the present invention is:
1, synergistic effect is obvious: composition shows good synergistic effect in certain ratio range, has improved the protection effect of composition.
2, reduce use cost: because of composite have improve preventive effect, reduced access times, reduced use cost;
3, delay pesticide resistance: the composition of two kinds of different mechanism of action is composite, pathogen is difficult for developing immunity to drugs, and delays pathogen to the drug-fast generation of medicament.
Embodiment
Following examples are to further illustrate of the present invention, but the present invention is not limited to preparation, ratio and purposes in present embodiment.
Embodiment 1 12% chitosan oligosaccharide poly hexamethylene biguanide aqua
Chitosan oligosaccharide 2g is fully dissolved with acetic acid 10g, add poly hexamethylene biguanide 18g, lignosulfonates 3g, propane diols 2g, xanthans 3g, phenethyl phenol formaldehyde resin polyvinylether 4g, water complements to 100g, obtains 12% chitosan oligosaccharide poly hexamethylene biguanide aqua.
Embodiment 2 6% chitosan oligosaccharide hexamethylene microemulsions
Chitosan oligosaccharide 1g acetic acid 10g, hexamethylene 5g, acetone 10g, alkyl polyoxyethylene ether and polyoxyethylene nonylphenol ether 5g, propane diols 1g, urea 2g, slowly adds water and complements to 100g, 6% chitosan oligosaccharide hexamethylene microemulsion.
Embodiment 3 4% chitosan oligosaccharide poly hexamethylene biguanide phosphate aqueous emulsions
Chitosan oligosaccharide 2g, poly hexamethylene biguanide phosphate 2g, N-repefral 4g, nonyl phenol benzene oxygen vinethene 3g, 2,6-di-tert-butyl-4-methy phenol 2g, ethylene glycol 3g, polyvinyl alcohol 1g, Sodium Benzoate 1g, silicone defoaming agent 0.5g, water complements to 100g, 4% chitosan oligosaccharide poly hexamethylene biguanide phosphate aqueous emulsion.
Embodiment 4 22% chitosan oligosaccharide poly hexamethylene biguanide suspending agents
Chitosan oligosaccharide 2g, poly hexamethylene biguanide 20g, sodium lignin sulfonate 5g, Magnesiumaluminumsilicate 2g, glycerine 5g are fully mixed, and the 25g that adds water fully grinds, and water complements to 100g, obtains 22% chitosan oligosaccharide poly hexamethylene biguanide suspending agent.
Embodiment 5 8% chitosan oligosaccharide hydrochloride poly hexamethylene biguanide nitrate suspending agents
Chitosan oligosaccharide hydrochloride 6g, poly hexamethylene biguanide nitrate 2g, sodium lignin sulfonate 5g, Magnesiumaluminumsilicate 2g, glycerine 5g are fully mixed, the 25g that adds water fully grinds, water complements to 100g, obtains 8% chitosan oligosaccharide nitrate hexamethylene suspending agent.
Embodiment 6 8% chitosan oligosaccharide sulphate poly hexamethylene biguanide carbonate suspending agents
Chitosan oligosaccharide sulphate 6g, poly hexamethylene biguanide phosphate 2g, sodium lignin sulfonate 5g, Magnesiumaluminumsilicate 2g, glycerine 5g are fully mixed, the 25g that adds water fully grinds, water complements to 100g, obtains 8% chitosan oligosaccharide carbonate poly hexamethylene biguanide phosphate suspending agent.
Embodiment 7 10% chitosan oligosaccharide poly hexamethylene biguanide water dispersible granules
Chitosan oligosaccharide 5g, poly hexamethylene biguanide 5g, calcium lignosulfonate 5g, octyl phenol polyglycol ether 2g, gum Arabic 5g are fully mixed, white carbon complements to 100g to be mixed, mixture is carried out to granulation after ultra-fine grinding, dry, screening, both made 10% chitosan oligosaccharide poly hexamethylene biguanide water dispersible granules.
Embodiment 8 6% chitosan oligosaccharide hydrochloride poly hexamethylene biguanide sulphate water dispersible granules
Chitosan oligosaccharide hydrochloride 5g, poly hexamethylene biguanide sulphate 1g, calcium lignosulfonate 5g, octyl phenol polyglycol ether 2g, gum Arabic 5g are fully mixed, white carbon complements to 100g to be mixed, mixture is carried out to granulation after ultra-fine grinding, dry, screening, both made 6% chitosan oligosaccharide hydrochloride poly hexamethylene biguanide sulphate water dispersible granules.
Embodiment 9 6% chitosan oligosaccharide phosphate poly hexamethylene biguanide water dispersible granules
Chitosan oligosaccharide phosphate 4g, poly hexamethylene biguanide 2g, calcium lignosulfonate 5g, octyl phenol polyglycol ether 2g, gum Arabic 5g are fully mixed, white carbon complements to 100g to be mixed, mixture is carried out to granulation after ultra-fine grinding, dry, screening, both made 6% chitosan oligosaccharide phosphate poly hexamethylene biguanide water dispersible granules.
Embodiment 10 10% chitosan oligosaccharide poly hexamethylene biguanide wetting powders
Chitosan oligosaccharide 9g, poly hexamethylene biguanide 1g, sodium alkyl benzene sulfonate 2g, kaolin are supplied to 100g and mix, each component is dry, cooling, levigate, be both mixed with 10% chitosan oligosaccharide poly hexamethylene biguanide wetting powder.
Embodiment 11 8% chitosan oligosaccharide sulphate poly hexamethylene biguanide stearate wetting powders
Chitosan oligosaccharide sulphate 4g, poly hexamethylene biguanide stearate 4g, sodium alkyl benzene sulfonate 2g, kaolin are supplied to 100g to be mixed, each component is dry, cooling, levigate, be both mixed with 8% chitosan oligosaccharide sulphate poly hexamethylene biguanide stearate wetting powder.
Embodiment 12 10% chitosan oligosaccharide phosphate poly hexamethylene biguanide acetate wetting powders
Chitosan oligosaccharide phosphate 2g, poly hexamethylene biguanide acetate 8g, sodium alkyl benzene sulfonate 2g, kaolin are supplied to 100g and mix, each component is dry, cooling, levigate, be both mixed with 10% chitosan oligosaccharide phosphate poly hexamethylene biguanide acetate wetting powder.
The effect of embodiment 13 compositions to watermelon blight
According to scheme, preparation built agent and single dose, aqua preparation, and carry out active preliminary experiment.According to trial test, preparation is mixed with to the concentration needing.Before selecting, stubble watermelon blight morbidity field, arranges field evenly.The preparation of the different medicaments of medication is evenly dressed seed (concentration is in effective milligram quantities of every kilogram of seed with medicament), is sowed Routine Management.In the time of disease onset, investigate watermelon plant diseases situation.Use Abbot formula, convert percentage to preventive effect.
In theoretical effect, x is the effect of the substance A of concentration while being a, and y is the effect of the substance B of concentration while being b, and relatively theoretical effect and actual effect evaluated the synergy of composition, while being greater than theoretical preventive effect taking actual preventive effect as synergistic effect.Composition the results are shown in Table 1 to watermelon disease.
The effect of table 1 composition to watermelon blight
The test of composition by containing oligosaccharides and poly hexamethylene biguanide to watermelon blight, as seen from Table 1, in the time that composition proportioning is 1:1, the composition of composition, chitosan oligosaccharide sulphate and the poly hexamethylene biguanide of the composition of chitosan oligosaccharide and poly hexamethylene biguanide, chitosan oligosaccharide hydrochloride and poly hexamethylene biguanide to the actual effect of watermelon blight all higher than composition theoretical preventive effect.Obviously, the composition of oligosaccharides and poly hexamethylene biguanide is synergy to watermelon blight.
Embodiment 14 compositions are to citrus bacterial canker disease field trial
According to scheme, preparation built agent and single dose, and carry out active preliminary experiment.According to determination of activity trial test, preparation is mixed with to the concentration needing.Before test, community is set, lists, and establish corresponding single dose and blank, adopt the conventional conventional spray of manual sprayer.After the 1st spraying, 7-10d sprays 1 time again, and after the 2nd dispenser, 10-14d investigates the citrus bacterial canker disease incidence of listing and processing.Use Abbot formula, convert percentage to preventive effect.
In theoretical effect, x is the effect of the substance A of concentration while being a, and y is the effect of the substance B of concentration while being b, and relatively theoretical effect and actual effect evaluated the synergy of composition, while being greater than theoretical preventive effect taking actual preventive effect as synergistic effect.Composition the results are shown in Table 2 to the control efficiency of citrus bacterial canker disease.
Table 2 composition is to citrus bacterial canker disease field effect
The test of composition by containing oligosaccharides and poly hexamethylene biguanide to citrus bacterial canker disease, as seen from Table 2, in the time that composition proportioning is 4:1-1:8, the composition of composition, chitosan oligosaccharide sulphate and the poly hexamethylene biguanide of the composition of chitosan oligosaccharide and poly hexamethylene biguanide, chitosan oligosaccharide hydrochloride and poly hexamethylene biguanide to the actual effect of citrus bacterial canker disease all higher than composition theoretical preventive effect.Obviously, the bactericidal composition of oligosaccharides and poly hexamethylene biguanide is synergy to citrus bacterial canker disease.
The effect of embodiment 15 compositions to rice disease
According to scheme, preparation built agent and single dose preparation, and carry out active preliminary experiment.According to determination of activity trial test, preparation is mixed with to the concentration needing.Select once to fall ill rice field, with medicament is dressed seed (concentration is in effective milligram quantities of every kilogram of seed with medicament) to rice paddy seed, sowing, seedling.In the time that blank bakanae disease of rice occurs, institute an inquiry, every processing is by 5 samplings, and every 50 strains, measure the percentage that infect on plant blade face.Use Abbot formula, convert percentage to preventive effect.
In theoretical effect, x is the effect of the substance A of concentration while being a, and y is the effect of the substance B of concentration while being b, and relatively theoretical effect and actual effect evaluated the synergy of composition, while being greater than theoretical preventive effect taking actual preventive effect as synergistic effect.Composition to the preventive effect of bakanae disease of rice in table 3.
Table 3 composition is to bakanae disease of rice field effect
The test of composition by containing oligosaccharides and poly hexamethylene biguanide or its salt to bakanae disease of rice, as seen from Table 3, in the time that composition proportioning is 2:1-1:8, the phosphatic composition of the composition of the composition of chitosan oligosaccharide phosphate and poly hexamethylene biguanide, chitosan oligosaccharide and hexamethylene, chitosan oligosaccharide sulphate and poly hexamethylene biguanide to the actual effect of bakanae disease of rice all higher than composition theoretical preventive effect.Obviously, the composition of oligosaccharides and poly hexamethylene biguanide or its salt is synergy to bakanae disease of rice.
The effect of embodiment 16 compositions to pepper virus disease
According to scheme, preparation built agent and single dose preparation, and carry out active preliminary experiment.According to determination of activity trial test, preparation is mixed with to the concentration needing.Before test, establish corresponding single dose and blank in capsicum field, adopt the conventional conventional spray of manual sprayer, every medicament sprays 50 strains.7-10d dispenser 1 time again after the 1st dispenser.10-20d after the 2nd dispenser, investigates the pepper plant virus disease situation of listing.Use Abbot formula, convert percentage to preventive effect.
In theoretical effect, x is the effect of the substance A of concentration while being a, and y is the effect of the substance B of concentration while being b, and relatively theoretical effect and actual effect evaluated the synergy of composition, while being greater than theoretical preventive effect taking actual preventive effect as synergistic effect.Composition to the effect of pepper plant virus disease in table 4.
Table 4 composition is to pepper virus disease field effect
The test of composition by containing oligosaccharides and poly hexamethylene biguanide to pepper virus disease, as seen from Table 4, in the time that composition proportioning is 1:2-2:1, the composition of composition, chitosan oligosaccharide sulphate and the poly hexamethylene biguanide of the composition of chitosan oligosaccharide and poly hexamethylene biguanide, chitosan oligosaccharide hydrochloride and poly hexamethylene biguanide to the actual effect of pepper virus disease all higher than composition theoretical preventive effect.Obviously, the composition of oligosaccharides and poly hexamethylene biguanide is synergy to pepper virus disease.
Claims (10)
1. the composition containing oligosaccharides and poly hexamethylene biguanide or its salt, it is characterized in that in said composition, oligosaccharides is one or more in chitosan oligosaccharide, chitosan oligosaccharide hydrochloride, chitosan oligosaccharide sulphate, chitosan oligosaccharide phosphate, and the ratio of quality and the number of copies of oligosaccharides and poly hexamethylene biguanide or its salt is 1:20-20:1.
2. according to the composition of claim 1, it is characterized in that ratio of quality and the number of copies is 1:10-10:1.
3. according to the composition of claim 1 or 2, it is characterized in that cosmocil stearate is the one in cosmocil stearate acid, poly hexamethylene biguanide phosphate, poly hexamethylene biguanide nitrate, poly hexamethylene biguanide carbonate, poly hexamethylene biguanide sulphate, poly hexamethylene biguanide stearate, poly hexamethylene biguanide acetate.
4. according to the composition of claim 3, it is characterized in that the quality sum of oligosaccharides and dithianon accounts for the 1%-80% of composition gross mass.
5. according to the composition of claim 4, it is characterized in that composition makes aqua, microemulsion, aqueous emulsion, suspending agent, water dispersible granules, wetting powder.
6. the application method of the composition of claim 5, is characterized in that composition is for the plant spraying to control, filling root, seed dressing etc.
7. according to the method for claim 6, it is characterized in that plant is watermelon, oranges and tangerines, paddy rice, capsicum, apple, pears, grape, lichee, cucumber, turfgrass, rape, wheat, flowers.
8. according to the method for claim 7, it is characterized in that plant is watermelon, oranges and tangerines, paddy rice, capsicum.
9. composition claimed in claim 5 is for preventing and treating the purposes of fungi, bacterium and the viral multiple diseases causing.
10. purposes according to claim 9, is characterized in that disease is watermelon blight, citrus bacterial canker disease, bakanae disease of rice, pepper virus disease etc.
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