CN104127797A - Traditional Chinese medicine preparation for treating aphasia after craniocerebral trauma and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating aphasia after craniocerebral trauma and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating aphasia after craniocerebral trauma. The traditional Chinese medicine preparation is prepared from the following raw materials: angelica sinensis, ligusticum wallichii, salvia miltiorrhiza, Chinese starjasmine stem, lumbricus, flowers carthami, radix cyathulae, fried astragalus membranaceus, dried rehmannia root, radix glehniae, radix ophiopogonis, dendrobe, rhizoma acori graminei, fructus alpiniae oxyphyllae, fructus amomi, acanthopanax, bombyx batryticatus, caltrop and musk according to a certain weight ratio. The traditional Chinese medicine preparation has the efficacies of dispelling stasis and dredging collaterals, reinforcing qi and nourishing yin, and activating the brain and regaining consciousness, and aphasia after craniocerebral trauma can be effectively treated.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for the treatment of aphasia after craniocerebral trauma and preparation method thereof.
Background technology
Craniocerebral injury is a kind of brain tissue impairment of acute generation, be due to external force direct or indirect act on the damage that head causes, comprise head soft tissue injury, fracture of skull and brain injury.Craniocerebral trauma can cause many complication and syndrome.Common complication has dizziness headache, vomiting and nausea, dysphoria or apathetic expression, the symptom such as even occur hemiplegia, aphasia, remain unconscious.The traditional Chinese medical science is thought all YANG-meridians meeting into the head, the gas of the clear sun of vital organs of the human body elite all comes together in this, is again brain place, mainly relies on Liver and kidney essence and blood and moistens foster, and transporting and transforming function of the spleen and stomach essence of water and grain, in defeated cloth QI and blood, fill and brain, clear-headed and clear-sighted, spirit and QI cleaning, the retardance of craniocerebral injury congestion, venation block, brain is become homeless foster, and QI and blood is disorderly contrary, becomes raw all diseases.The traditional Chinese medical science is mainly deficiency of kidney-essence for the dialectical Analyses of after craniocerebral injury aphasia, YANG-orifices failing to be nourished, and obstruction of collateral caused by windphlegm, tongue key is obstructed.
The aphasia state of Patients With Head Trauma brings slight illness not only to patient oneself, has brought huge psychological burden and financial burden also to patient's household.Even at present after treatment craniocerebral trauma, the Western medicine of aphasia is few, and the treatment of doctor trained in Western medicine is still taking chemotherapy as main, and treatment cycle is long, and side effect is large, takes for a long time Western medicine, is expendable to the damage of hepatic and renal function.Treatment by Chinese herbs short treating period, and no pain, treating both the principal and secondary aspects of a disease, curative effect is reliable, and the patient after healing is difficult for recurrence, and in therapeutic process, can not produce damage to other organs.Chinese medicine truly has its distinctive feature, clinic research promotion aspect aphasia after treatment craniocerebral trauma.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of aphasia after craniocerebral trauma, this Chinese medicine preparation for craniocerebral trauma after aphasia there is good effect, cure rate is high, have no side effect, taking convenience, cheap, the feature that healing time is short.Alleviate patient's misery, for patient and patient's household has alleviated burden and economic pressures at heart.
Inventor is in clinical treatment practice for many years, but the clinical symptoms of the patient who observes Consciousness aphasia after craniocerebral trauma in treatment, and patient household expects that patient can recover normal mood, according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out a kind of new formula for the treatment of the Chinese medicine preparation of aphasia after craniocerebral trauma repeatedly, can make in the short period of time the patient can normal speech, exchange.The present invention has evident in efficacy, instant effect, and cure rate is high, has no side effect, taking convenience, cheap feature.
The effect of Chinese medicine of the present invention:
Wherein:
Radix Angelicae Sinensis: be the dry root of umbelliferae angelica.Nature and flavor are sweet, pungent, bitter, temperature.Return liver, the heart, spleen channel.Effect: enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.Radix Angelicae Sinensis has inhibitory action to central nervous system, and volatile oil has the effects such as calmness, hypnosis, analgesia, anesthesia.For blood deficiency and yellow complexion, dizzy cardiopalmus, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores.Carry according to " book on Chinese herbal medicine is just ": " its sweet in the mouth and weigh, therefore specially can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, can support nutrition blood, QI invigorating spermatogenesis, settling five organs, body by force, beneficial mind, all tangible deficient diseases, nothing unsuitable." Chinese angelica blood supplementing invigorates blood circulation, and makes blood abundance, makes congestion eliminating stagnation and tissue regeneration promoting blood, to moisten the body that takes care of health.The same use of the Radix Astragali and Radix Angelicae Sinensis, the gas of the large tonifying the lung spleen of the Radix Astragali, has admittedly outer energy; Radix Angelicae Sinensis benefit blood and battalion are blood man gas medicines, with pungent elevator behavior use, taking gentle Xin Run as merit.Two tastes close it, just can Yin grows while yang is generatings, therefore damage traumatology disease in medical treatment wound, no matter Qi and blood deficiency, has or not heating, multiplexly returns, stilbene matches.
Rhizoma Chuanxiong: be the dry rhizome of samphire Rhizoma Chuanxiong.Nature and flavor: pungent, temperature.Return liver, gallbladder, heart channel.Effect: blood-activating and qi-promoting, wind-expelling pain-stopping, the pungent loose temperature of this product is logical, can top, up mountain peak, assign the sea of blood, outer thorough fur, bypass extremity, can invigorate blood circulation and can circulation of qi promoting, and it is the gas medicine in blood that former times people calls Rhizoma Chuanxiong, nearly says the functions such as pungent loose, the resolving depression of its residence, sensible, pain relieving.Rhizoma Chuanxiong has obvious sedation.
Radix Salviae Miltiorrhizae: be the dry root and rhizome of dicotyledon Labiatae salvia Radix Salviae Miltiorrhizae.Nature and flavor: hardship, is slightly cold.Gui Jing: enter the heart, Liver Channel.Effect: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind.For costa sternales hypochondriac pain, rheumatic arthralgia, lump in the abdomen caking." Japan hanako materia medica ": the sedate of reposing, tonneau GUAN-pulse.Control cold and hot labor, arthralgia, extremity are unsuccessful; Evacuation of pus pain relieving, granulation promoting is put on flesh; Broken stagnated blood, mends new hemopoietic; Peaceful tire, stillborn fetus falls; Under hemostasis metrorrhagia and leukorrhagia, adjust married woman's passages through which vital energy circulates irregular, blood evil thought is tired; Malignant boil scabies, the wart toxic swelling of going to live in the household of one's in-laws on getting married, erysipelas; Headache, acute conjunctivitis, hot temperature is mad vexed.With Radix Angelicae Sinensis, the same use of Rhizoma Chuanxiong, make the sedate of reposing, effect of the circulation of qi promoting of enriching blood strengthens.
Caulis Trachelospermi: be the leaf bine stem of apocynaceae plant trachelospermum jasminoide.Nature and flavor: be slightly cold, hardship.Return liver, kidney channel.Effect: dispel the wind, dredging collateral, hemostasis, repercussive.Dispelling the wind and dampness pathogens arthralgia pain, the contracture of muscle arteries and veins, carbuncle, sore throat, spits blood, traumatic injury, disease that postpartum lochia can't go.Caulis Trachelospermi can be treated rheumatism pyretic arthralgia, redness and swelling of joints, and normal and Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Cortex Phellodendri are equal to use.
Pheretima: be the dry body of Ju Yin section animal Pheretima aspergillum, popular Pheretimatschiliensis, William Pheretimatschiliensis or the blind Pheretimatschiliensis of comb.Nature and flavor: salty, cold.Return liver, spleen, urinary bladder channel.Effect: heat clearing away arresting convulsion, dredge the meridian passage, clearing heat and relieving dyspnea, relieving stranguria by diuresis.This product is cold in nature, can endogenous wind stopping relieving convulsion, be good at again heat clearing away arresting convulsion, therefore be applicable to the unconsciousness and delirium due to extreme heat causing wind syndrome, the traditional Chinese medical science is recorded Pheretima property and is walked to alter, be good at current meridians, the inrigorating qi and promoting blood circulation medicine compatibilities such as normal and the Radix Astragali, Radix Angelicae Sinensis, Rhizoma Chuanxiong, treat blood stagnancy due to deficiency of QI after apoplexy, and meridians are unfavorable, hemiplegia, mouthful eye tiltedly waits disease.
Flos Carthami: be the tubular corolla of feverfew Flos Carthami.Nature and flavor temperature, pungent.GUIXIN, Liver Channel.Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.The pungent loose temperature of Flos Carthami is logical, specially enters blood system, can blood circulation promoting and blood stasis dispelling, and the pulse-taking that stimulates the menstrual flow, the mutual reinforcements between such as normal and Radix Angelicae Sinensis, Rhizoma Chuanxiong are use.
Radix Cyathulae: be the root of Amaranthus mangostanus L. section herbaceos perennial Radix Achyranthis Bidentatae or RADIX CYATHULAE.Nature and flavor: bitter, acid, flat.Return liver, kidney channel.Effect: eliminating blood stasis and inducing menstruation, conducting blood to flow downwards, invigorating the liver and kidney, bone and muscle strengthening.Radix Achyranthis Bidentatae is kind descendingly not only makes that menstruation is unobstructed, normal urination, large easy rushing down, and is easy to downward eliminating, and can make head and blood is descending above the waist, thereby alleviates head syndrome of fire-heat.Radix Cyathulae is partial to blood circulation promoting and blood stasis dispelling.
Radix Astragali Preparata: be the dry root of the leguminous plant Radix Astragali or Inner Mongolia Astragalis.Nature and flavor: sweet, tepor.Return lung, spleen, liver, kidney channel.Effect: tonifying Qi and lifting yang, consolidating superficial resistance arresting sweating, inducing diuresis to remove edema, the evacuation of pus of holder skin ulcer, regulating fluid apssage, on the books in " book on Chinese herbal medicine converges and says ": " arresting sweating is defended in the Radix Astragali, tonifying the lung spleen invigorating in fact, and the medicine of wind dispelling fortune poison is also.Therefore the people of yang deficiency, spontaneous perspiration frequently comes, be exterior deficiency and interspaces of skin and muscles being loose also, the Radix Astragali can be defended and arresting sweating in fact; The card of typhoid fever, row is delivered and evil no sweating, is interior deficiency and also weary in healthy energy, and the Radix Astragali can help Tianjin to help antiperspirant; The disease of harmful wind, partially invasion of vessels and brothers are with person, and the Radix Astragali can flourish muscles and bones; The card of carbuncle and ulcer, pus and blood internal ulceration, deficiency of YANG QI and do not hold back person, the Radix Astragali can granulation promoting meat, and the erosion of vulva can not rise and send out again, deficiency of YANG QI and unhealed, the Radix Astragali can granulation promoting meat.”。
Radix Rehmanniae: be the tuber of Scrophulariaceae herbaceos perennial Radix Rehmanniae.Nature and flavor: sweet, cold.GUIXIN, liver, kidney channel.Effect: clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting.Can be used for Tianjin wound thirsty, interior-heat is quenched one's thirst.This product is sweet cold, can be among heat clearing away YIN nourishing and the production of body fluid promoting Radix Ophiopogonis, Radix Adenophorae (Radix Glehniae) be equal to use.
Radix Glehniae: be the root of Umbelliferae herbaceos perennial glehnia littoralis.Nature and flavor: sweet, micro-hardship, be slightly cold.Return lung, kidney channel.Effect: nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid.Thirsty for lung-heat type cough, chronic cough expectorant blood, calentura Tianjin wound.
Radix Ophiopogonis: be the Liliaceae herbaceos perennial tuber of Radix Ophiopogonis.Nature and flavor: sweet, micro-hardship, be slightly cold.GUIXIN, lung, stomach warp.Effect: reinforcing stomach reg fluid, nourishing lung-YIN, relieving restlessness clears away heart-fire.Can clear away heart-fire Radix Ophiopogonis in yin nourishing, and relieving restlessness is calmed the nerves.Normal and Herba Dendrobii matches.
Herba Dendrobii: be the stem of the orchid family herbaceos perennial Dendrobium nobile, U.S. flower Herba Dendrobii, Herba Dendrobii, Dendrobium chrysanthum, Herba Dendrobii oculati.Nature and flavor: be slightly cold; Sweet.Return stomach, kidney channel.Function: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Lose for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision.
Rhizoma Acori Graminei: be the rhizome of ranunculaceae plant anemone altaica.Nature and flavor: warm, pungent.GUIXIN, liver, spleen channel.Effect: waking up the patient from unconsciousness by dissipating phlegm; Calm the nerves; A surname is wet to be amusing; Removing toxic substances.Cure mainly: main calentura coma; Epilepsy; Deafness with qi stagnation; Dreaminess is forgetful; Abdominal distention uncomfortable in chest; Inappetence; Rheumatic arthralgia; Carbuncle; Scabies.
Fructus Alpiniae Oxyphyllae: be the mature fruit of Zingiberaceae herbaceous plant Fructus Alpiniae Oxyphyllae.Nature and flavor: pungent, warm, return kidney, spleen channel.Function: temperature compensation astringency inducing, warm spleen antidiarrheal ， Gu Dan takes the photograph saliva, the kidney warming controlling nocturnal emission with astringent drugs reducing urination.Cure mainly spleen-kidney vacuity cold, abdominal pain diarrhea; Or kidney qi deficiency and coldness frequent micturition, the enuresis, seminal emission, nebulousurine; Or chronic diarrhea due to Deficiency and coldness of spleen and stomach and mouthful in saliva outflow and can not effector.
Fructus Amomi: be the mature fruit of Zingiberaceae herbaceos perennial Fructus Amomi, green shell sand or SEMEN AMOMI LONGILIGULA.Nature and flavor: pungent, warm.Return spleen, stomach, kidney channel.Effect: removing dampness appetizing, warming spleen and stopping diarrha, regulate the flow of vital energy antiabortive.
Radix Et Caulis Acanthopanacis Senticosi: be rhizome or the stem of Araliaceae Radix Et Caulis Acanthopanacis Senticosi.Nature and flavor: sweet, micro-hardship, temperature.Return spleen, lung, the heart, kidney channel.Effect: replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization.The gas of this product energy reinforcing the heart spleen, and QI invigorating to be to nourish blood, the beneficial will of calming the nerves.Control deficiency of both the heart and spleen, the insomnia of lack of preservation of spirit, forgetful, the product compatibility that can nourish heart, calm the nerves with Rhizoma Acori Graminei etc.
Bombyx Batryticatus: be the Bombycidae insecticide silkworm lethal dry body of larva infection (or artificial vaccination) muscardine in 4～5 ages.Nature and flavor: salty, pungent, flat.Return liver, lung, stomach warp.Effect: expelling wind to relieve convulsion, dissipating phlegm and resolving masses.Cure mainly: apoplectic aphasia, middle tuyere nose eye are oblique.
Fructus Tribuli: be the fruit of zygophyllaceae plant Fructus Tribuli.Nature and flavor: pungent, bitter, tepor; Slightly poisonous.Return Liver Channel.Effect: suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, antipruritic.Be used for having a headache dizzy, distending pain in the chest and hypochondrium, breast closes acute mastitis, conjunctival congestion cataracta, rubella pruritus.
Moschus: be the secretions in the ripe male body note capsule of animal in deer family woods Moschus moschiferous, horse Moschus moschiferous or former Moschus moschiferous.Nature and flavor: pungent, warm.GUIXIN, spleen channel.Effect: the refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain.The pungent temperature of Moschus, its QI exhaustion perfume (or spice), the property of walking to alter is very strong, has the very strong logical effect of closing refreshment of having one's ideas straightened out, and is the key medicine of the refreshment of having one's ideas straightened out.
The present invention selects Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Caulis Trachelospermi, Pheretima, Flos Carthami, Radix Cyathulae, Radix Astragali Preparata, Radix Rehmanniae, Radix Glehniae, Radix Ophiopogonis, Herba Dendrobii, Rhizoma Acori Graminei, Fructus Alpiniae Oxyphyllae, Fructus Amomi, Radix Et Caulis Acanthopanacis Senticosi, Bombyx Batryticatus, Fructus Tribuli, Moschus to combine, in side, Radix Angelicae Sinensis, the Radix Astragali are supported nutrition blood, tonifying QI to produce body fluid; Radix Salviae Miltiorrhizae, Caulis Trachelospermi blood circulation promoting and blood stasis dispelling; Moschus 12 warps that pass through, the kind logical all keys of whole body, are longer than the refreshment of having one's ideas straightened out, five eliminating blood stasis and smoothing collaterals, inrigorating qi and promoting blood circulation is altogether for monarch will.Pheretima is joined the Radix Astragali, Radix Angelicae Sinensis, Rhizoma Chuanxiong inrigorating qi and promoting blood circulation medicine, dredge the meridian passage, Flos Carthami, Radix Cyathulae blood circulation promoting and blood stasis dispelling, Radix Rehmanniae, Radix Glehniae, Radix Ophiopogonis, Herba Dendrobii clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, is more than ministerial drug, all the other various medicines are that adjuvant is formulated, in side, all medicine compatibilities, the monarch and his subjects pull together, help and make auxiliaryly altogether, make it to have eliminating blood stasis and smoothing collaterals, supplementing QI and nourishing YIN, effect of consciousness-restoring and orifice-opening, can effectively treat aphasia after craniocerebral trauma.
Medicine material consumption of the present invention is groped in a large number to sum up through inventor and is drawn, each raw material consumption is for all to have good curative effect in following weight parts scope: Radix Angelicae Sinensis 13-23g, Rhizoma Chuanxiong 7-17g, Radix Salviae Miltiorrhizae 19-29g, Caulis Trachelospermi 15-25g, Pheretima 4-14g, Flos Carthami 4-14g, Radix Cyathulae 10-20g, Radix Astragali Preparata 40-60g, Radix Rehmanniae 15-25g, Radix Glehniae 10-20g, Radix Ophiopogonis 10-20g, Herba Dendrobii 10-20g, Rhizoma Acori Graminei 13-23g, Fructus Alpiniae Oxyphyllae 13-23g, Fructus Amomi 3-9g, Radix Et Caulis Acanthopanacis Senticosi 10-20g, Bombyx Batryticatus 4-14g, Fructus Tribuli 15-25g, Moschus 0.05-0.3g.Wherein be preferably: Radix Angelicae Sinensis 18g, Rhizoma Chuanxiong 12g, Radix Salviae Miltiorrhizae 24g, Caulis Trachelospermi 20g, Pheretima 9g, Flos Carthami 9g, Radix Cyathulae 15g, Radix Astragali Preparata 50g, Radix Rehmanniae 20g, Radix Glehniae 15g, Radix Ophiopogonis 15g, Herba Dendrobii 15g, Rhizoma Acori Graminei 18g, Fructus Alpiniae Oxyphyllae 18g, Fructus Amomi 6g, Radix Et Caulis Acanthopanacis Senticosi 15g, Bombyx Batryticatus 9g, Fructus Tribuli 20g, Moschus 0.1g.
Medicine of the present invention can adopt the conventional preparation technology of Chinese medicine preparation, can be made into said dosage form on any pharmaceutics, as pill, powder, tablet, capsule, granule, syrup, oral liquid etc.For example can be by these crude drug grinds into fine powder, granularity is 80-120 order, gained fine powder is dropped into hybrid medicine blender and fully mix, and makes powder warm water and takes after mixing it with water.Can use decocting, obtain after filtration filtrate, add antiseptic to make oral liquid; Also can directly take if desired decoction.
The preferred method of the present invention is the concentrated method of Chinese medicine extraction:
Step 1: Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Pheretima, Radix Astragali Preparata, Radix Rehmanniae, Radix Glehniae, Radix Ophiopogonis, Fructus Alpiniae Oxyphyllae, Fructus Amomi, Radix Et Caulis Acanthopanacis Senticosi, Bombyx Batryticatus are ground into powder after pulverizing, crossed 200 order dusting covers.
Step 2: Caulis Trachelospermi, Radix Cyathulae, Rhizoma Acori Graminei, Fructus Tribuli, Flos Carthami, Herba Dendrobii are put into container, distillation, get volatile oil, medicinal residues and mother solution add Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Pheretima, Radix Astragali Preparata, Radix Rehmanniae, Radix Glehniae, Radix Ophiopogonis, Fructus Alpiniae Oxyphyllae, Fructus Amomi, Radix Et Caulis Acanthopanacis Senticosi, Bombyx Batryticatus to decoct again, filter.Medicinal residues add water again, decoct, and filter waste.Merge filtrate twice, then the concentrated ethanol that adds, places precipitation, filters, and abandons precipitation, filtrate recycling ethanol.
Step 3: the volatile oil that adds Caulis Trachelospermi, Radix Cyathulae, Rhizoma Acori Graminei, Fructus Tribuli, Flos Carthami, Herba Dendrobii to distill out, the thick paste of relative density 1.15～1.20 under 75 DEG C of environment of simmer down to.
Step 4: the fine powder that Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Pheretima, Radix Astragali Preparata, Radix Rehmanniae, Radix Glehniae, Radix Ophiopogonis, Fructus Alpiniae Oxyphyllae, Fructus Amomi, Radix Et Caulis Acanthopanacis Senticosi, Bombyx Batryticatus are worn into adds in thick paste, is uniformly mixed, and adds Mel, the honeyed pill of preparation 8g/ grain.
Medicine of the present invention has eliminating blood stasis and smoothing collaterals, supplementing QI and nourishing YIN, and effect of consciousness-restoring and orifice-opening, and good effect, cure rate is high, has no side effect, taking convenience, cheap, make after craniocerebral trauma the clear-headed but patient of aphasia normally exchange.The mode that this Chinese medicine preparation adopts is treated and can be reduced the infringement of Western medicine to hepatic and renal function, reduces the generation of complication.According to clinical 190 routine patients are observed to statistics, use 90%, two of one of the medicine of the present invention total effective rate course for the treatment of total effective rate course for the treatment of 98%.
Detailed description of the invention
Embodiment mono-, Radix Angelicae Sinensis 13g, Rhizoma Chuanxiong 7g, Radix Salviae Miltiorrhizae 19g, Caulis Trachelospermi 15g, Pheretima 4g, Flos Carthami 4g, Radix Cyathulae 10g, Radix Astragali Preparata 40g, Radix Rehmanniae 15g, Radix Glehniae 10g, Radix Ophiopogonis 10g, Herba Dendrobii 10g, Rhizoma Acori Graminei 13g, Fructus Alpiniae Oxyphyllae 13g, Fructus Amomi 3g, Radix Et Caulis Acanthopanacis Senticosi 10g, Bombyx Batryticatus 4g, Fructus Tribuli 15g, Moschus 0.05g.Embodiment bis-, Radix Angelicae Sinensis 18g, Rhizoma Chuanxiong 12g, Radix Salviae Miltiorrhizae 24g, Caulis Trachelospermi 20g, Pheretima 9g, Flos Carthami 9g, Radix Cyathulae 15g, Radix Astragali Preparata 50g, Radix Rehmanniae 20g, Radix Glehniae 15g, Radix Ophiopogonis 15g, Herba Dendrobii 15g, Rhizoma Acori Graminei 18g, Fructus Alpiniae Oxyphyllae 18g, Fructus Amomi 6g, Radix Et Caulis Acanthopanacis Senticosi 15g, Bombyx Batryticatus 9g, Fructus Tribuli 20g, Moschus 0.1g.Embodiment tri-, Radix Angelicae Sinensis 23g, Rhizoma Chuanxiong 17g, Radix Salviae Miltiorrhizae 29g, Caulis Trachelospermi 25g, Pheretima 14g, Flos Carthami 14g, Radix Cyathulae 20g, Radix Astragali Preparata 60g, Radix Rehmanniae 25g, Radix Glehniae 20g, Radix Ophiopogonis 20g, Herba Dendrobii 20g, Rhizoma Acori Graminei 23g, Fructus Alpiniae Oxyphyllae 23g, Fructus Amomi 9g, Radix Et Caulis Acanthopanacis Senticosi 20g, Bombyx Batryticatus 14g, Fructus Tribuli 25g, Moschus 0.3g.
The clinical statistics data that patient uses medicine of the present invention below:
One, physical data
After accepting outpatient service craniocerebral trauma year October in November, 2011 to 2013 for medical treatment, regain consciousness but patient's totally 380 examples of aphasia, patient is divided into observation group and matched group at random, wherein male's 200 examples, women's 180 examples, M-F 1.1:1, maximum 64 years old age, minimal ages 23 years old, 41 years old mean age, every basic document such as two groups of patient ages, sex, course of disease is basic identical, difference not statistically significant (P > 0.05).
Two, Therapeutic Method:
1, observation group is according to medicine embodiment bis-of the present invention, and the honeyed pill prepared of preferred preparation method, sooner or later service once, and each 2, decoction being taken warmly.It within 10th, is a course for the treatment of.
2, matched group is according to the capsule for the treatment of in CN 103933290A after the optimum weight proportioning preparation of medicine of craniocerebral injury and preparation method thereof, each 3-4 grain, and three times on the one 15 days is a course for the treatment of.
Three, efficacy assessment standard:
1, cure: can correctly talk with, language is fluent;
2, take a turn for the better: energy simple dialog, language undercurrent profit, pronounces indistinctly sometimes;
3, do not heal: aphasia is without any improvement.
Four, observation group's result statistics
Matched group result statistics
Wherein: total effective rate=cure rate+improvement rate
Take two groups of patients', two courses for the treatment of Comparison of therapeutic situation
Can find that by contrasting two groups of patients' treatment total effective rate observation group is apparently higher than matched group, explanation thus, Chinese medicine of the present invention aphasia after treatment craniocerebral trauma has good clinical effectiveness, can effectively improve the cure rate for the treatment of, is worth promoting in clinical practice.
Model case and curative effect:
Case one, Wu, man, 27 years old, because fighting, damage head, on inspection: subarachnoid hemorrhage; The left side pillow soft and soggy tissue contusion of top head; Due to head severe injury, after regaining consciousness, cause aphasia, saw a doctor in here afterwards, patient adopted after 2 courses for the treatment of of embodiment bis-treatment by Chinese herbs, although patient pronounces indistinctly, can simply exchange, continue to take 4 courses for the treatment of of this medicine, patient's normal dialog, and articulate.
Case two, Zheng, female, 29 years old, because of traffic accident, head was clashed into, and after regaining consciousness, can not talk, and was diagnosed as: left side epidural hematoma; Left side pillow top head skin soft tissue injury, patient comes here and seeks medical advice, and employing embodiment bis-treatment by Chinese herbs can be talked with after 3 courses for the treatment of normally, and language is fluent.
Case three, Zhao, man 49 years old, does not descend the heart to fall on room, traumatic injury head, causes pronouncing indistinctly after regaining consciousness, and ability to speak is unfluent, can not normally exchange, sought medical advice in here afterwards, and patient can speak after adopting 5 courses for the treatment of of embodiment bis-treatment by Chinese herbs, and it is clear to stutter, without complication.
Claims (3)
1. treat the Chinese medicine preparation of aphasia after craniocerebral trauma for one kind, it is characterized in that, this Chinese medicine preparation is to be made up of the medicine of following weight portion: Radix Angelicae Sinensis 13-23g, Rhizoma Chuanxiong 7-17g, Radix Salviae Miltiorrhizae 19-29g, Caulis Trachelospermi 15-25g, Pheretima 4-14g, Flos Carthami 4-14g, Radix Cyathulae 10-20g, Radix Astragali Preparata 40-60g, Radix Rehmanniae 15-25g, Radix Glehniae 10-20g, Radix Ophiopogonis 10-20g, Herba Dendrobii 10-20g, Rhizoma Acori Graminei 13-23g, Fructus Alpiniae Oxyphyllae 13-23g, Fructus Amomi 3-9g, Radix Et Caulis Acanthopanacis Senticosi 10-20g, Bombyx Batryticatus 4-14g, Fructus Tribuli 15-25g, Moschus 0.05-0.3g.
2. the Chinese medicine preparation of aphasia after treatment craniocerebral trauma according to claim 1, it is characterized in that, made by the medicine of following weight portion: Radix Angelicae Sinensis 18g, Rhizoma Chuanxiong 12g, Radix Salviae Miltiorrhizae 24g, Caulis Trachelospermi 20g, Pheretima 9g, Flos Carthami 9g, Radix Cyathulae 15g, Radix Astragali Preparata 50g, Radix Rehmanniae 20g, Radix Glehniae 15g, Radix Ophiopogonis 15g, Herba Dendrobii 15g, Rhizoma Acori Graminei 18g, Fructus Alpiniae Oxyphyllae 18g, Fructus Amomi 6g, Radix Et Caulis Acanthopanacis Senticosi 15g, Bombyx Batryticatus 9g, Fructus Tribuli 20g, Moschus 0.1g.
3. treat the preparation method of the Chinese medicine preparation of aphasia after craniocerebral trauma for one kind, it is characterized in that, its preparation method is as follows: step 1: Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Pheretima, Radix Astragali Preparata, Radix Rehmanniae, Radix Glehniae, Radix Ophiopogonis, Fructus Alpiniae Oxyphyllae, Fructus Amomi, Radix Et Caulis Acanthopanacis Senticosi, Bombyx Batryticatus are ground into powder after pulverizing, crossed 200 order dusting covers; Step 2: Caulis Trachelospermi, Radix Cyathulae, Rhizoma Acori Graminei, Fructus Tribuli, Flos Carthami, Herba Dendrobii are put into container, and distillation, gets volatile oil, medicinal residues and mother solution add Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Pheretima, Radix Astragali Preparata, Radix Rehmanniae, Radix Glehniae, Radix Ophiopogonis, Fructus Alpiniae Oxyphyllae, Fructus Amomi, Radix Et Caulis Acanthopanacis Senticosi, Bombyx Batryticatus to decoct again, filter, and medicinal residues add water again, decoct, filter waste, merge filtrate twice, then the concentrated ethanol that adds, places precipitation, filters, abandon precipitation, filtrate recycling ethanol; Step 3: the volatile oil that adds Caulis Trachelospermi, Radix Cyathulae, Rhizoma Acori Graminei, Fructus Tribuli, Flos Carthami, Herba Dendrobii to distill out, the thick paste of relative density 1.15～1.20 under 75 DEG C of environment of simmer down to; Step 4: the fine powder that Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Pheretima, Radix Astragali Preparata, Radix Rehmanniae, Radix Glehniae, Radix Ophiopogonis, Fructus Alpiniae Oxyphyllae, Fructus Amomi, Radix Et Caulis Acanthopanacis Senticosi, Bombyx Batryticatus are worn into adds in thick paste, is uniformly mixed, and adds Mel, the honeyed pill of preparation 8g/ grain.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107753879A (en) * | 2017-12-08 | 2018-03-06 | 唐佳艳 | The Chinese medicine composition and its preparation method of a kind of reducing blood lipid |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110250183A1 (en) * | 2008-11-10 | 2011-10-13 | Moleac Pte. Ltd. | Combination Therapy for Treatment of Patients with Neurological Disorders and Cerebral Infarction |
| CN102935153A (en) * | 2012-08-14 | 2013-02-20 | 孙殿良 | Qi reinforcing qianzheng pills for cerebral thrombosis disease treatment |
| CN103007064A (en) * | 2012-12-31 | 2013-04-03 | 尚欣 | Traditional Chinese medicine (TCM) composition for treating cerebral posterior circulation ischemia |
-
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110250183A1 (en) * | 2008-11-10 | 2011-10-13 | Moleac Pte. Ltd. | Combination Therapy for Treatment of Patients with Neurological Disorders and Cerebral Infarction |
| CN102935153A (en) * | 2012-08-14 | 2013-02-20 | 孙殿良 | Qi reinforcing qianzheng pills for cerebral thrombosis disease treatment |
| CN103007064A (en) * | 2012-12-31 | 2013-04-03 | 尚欣 | Traditional Chinese medicine (TCM) composition for treating cerebral posterior circulation ischemia |
Non-Patent Citations (2)
| Title |
|---|
| 王策等: "王经通副主任医师治疗脑外伤后遗症经验总结", 《中国中医骨伤科杂志》 * |
| 许庆友等: "颅脑损伤后遗症的中医治疗及研究进展", 《辽宁中医杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107753879A (en) * | 2017-12-08 | 2018-03-06 | 唐佳艳 | The Chinese medicine composition and its preparation method of a kind of reducing blood lipid |
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