CN104107253A - Traditional Chinese medicine for treating pityriasis rubra pilaris - Google Patents
Traditional Chinese medicine for treating pityriasis rubra pilaris Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine for treating pityriasis rubra pilaris. The traditional Chinese medicine is prepared from the following medicinal materials by weight: 10 parts of Lychnis senno Sieb., 15 parts of Boletinus cavipes, 14 parts of Kopsia officinalis Tsiang, 10 parts of Artemisia dracunculus L., 5 parts of Cirsium souliei, 14 parts of Biondia hnryi, 10 parts of Castanopsis chinensis Hance, 8 parts of leaf of zelkova schneideriana, 6 parts of Phlegmariurus austrosinicus, 8 parts of Hyssopus latilabiatus, 12 parts of Radix potentillae anserinae, 12 pars of lombardy poplar, 10 parts of Pilea peperomioides Diels, 8 parts of Vernonia squarrosa, 20 parts of Polygonum perfoliatum L., 10 parts of Impetiens uliginosa Franch and 6 parts of herb of tuberousroot jerusalemsage. According to results of clinical experiments, the traditional Chinese medicine can safely and effectively treat pityriasis rubra pilaris.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of pityriasis rubra pilaris.
Background technology
Pityriasis rubra pilaris is a kind of agnogenic rare chronic inflammatory disease dermatoses.Show as the hard pointed little pimple of hair follicle, there is black keratotic plug in central authorities, normal intensive in blocks, surface companion's bran shape squama.Though this disease symptoms is light, course of disease delay; Adult sends out patient period may be with dimension methanol in conjunction with relevant (acquisition sexual types) such as albumen defect, low blood plasma vitamin A or dysthyreosises, and morbidity is very fast, can develop into erythroderma.The most remarkable histopathologic characteristics be keratinization of epidermis excessively and hair follicle horn plug, in bolt, have a hair.Near follicular orifice, have point-like parakeratosis, granular layer slightly thickens, and the irregular plumpness of spinous layer can have liquefaction of basal cell to change.
For pityriasis rubra pilaris, still lack at present satisfied medicine.
The present Research of the related medical material of Chinese medicine of the present invention is as follows:
Herba lychnidis senno [source] medical material Ji Yuan: be the whole herb with root of pinkwort LychnisFlos-Cuculi.Latin plant animal mineral name: Lychnis senno Sieb.et Zucc gathers and stores: gather in the crops 1 annual August, extracts with root herb, shrugs off silt, dries.[nature and flavor] are sweet; Light; Cold in nature.[function cures mainly] clearing away heat and promoting diuresis; Eliminating stasis to stop pain.Main fever caused by exogenous pathogens; Pyretic stranguria; Have loose bowels; Herpes zoster; Rheumatic arthralgia; Traumatic injury.[usage and dosage] is for oral administration: decoct soup, root 9～15g herb 15～30g; Or bubble spills.External: appropriate, grind into powder and dress.The conventional Chinese herbal medicine > > in [each family is discussed] < < Sichuan: loose blood, antidiarrheal.Control traumatic injury, summer-heat diarrhoea.
False Hepar Bovis seu Bubali Boletinus cavipes (Opat.) Kalchbr. of false Hepar Bovis seu Bubali [source] the Mycophyta Basidiomycetes of the empty handle empty handle of Agaricales Boletaceae, is used as medicine with sporophore.[habitats distribution] is in being born in ground in woods in two seasons of autumn in summer.Be distributed in Jilin, Shanxi.[nature and flavor] are micro-salty, warm.[function cures mainly] chases after wind, cold expelling, and relaxing muscles and tendons, active.Can control lumbago and skelalgia, numb hand and foot, grain does not relax.[usage and dosage] enters ball powder.
Fructus Seu Folium Kopsiae Officinalis [source] medical material Ji Yuan: be fruit, the leaf of apocynaceae plant Yunnan stamen wood.Latin plant animal mineral name: Kopsia officinalis Tsiang et P.T.Li gathers and stores: receive fruit autumn, leaf can be adopted the whole year, dries.[nature and flavor] hardship; Pungent; Property is put down, poisonous.[function cures mainly] anti-inflammatory analgetic; Dispelling, collateral-activating.Main laryngopharynx swelling and pain; Rheumatic arthralgia; Numb limbs and tense tendons.[usage and dosage] is for oral administration: decoct soup, 3-6g; Or the drink of steeping in wine.External: appropriate, leaf is decocted washing.
Green pepper Artemisia [source] medical material Ji Yuan: be the herb root of feverfew Artemisia dracunculus.Latin plant animal mineral name: Artemisia dracunculus L.[A.glauca auct.Non Pall.ex Willd.] gather and store: when summer Mo blooms in end, extract aerial parts, dry in the shade.The 9-10 month uproots, and cleans, and dries.[nature and flavor] acrid in the mouth; Micro-hardship; Warm in nature.[function cures mainly] expelling wind and cold; Lung qi dispersing cough-relieving.Main anemofrigid cold; Cough and asthma.[usage and dosage] is for oral administration: decoct soup, 10-15g.
Cirsium souliei [source] medical material Ji Yuan: be the herb of feverfew Cirsium souliei.Latin plant animal mineral name: Cirsium souliei (Franch.) Mattf.[Cnicum soulier Franch.] to gather and store: summer, autumn gather, and cutting is dried.[nature and flavor] sweet in the mouth; Bitter; Cool in nature.[function cures mainly] cooling blood for hemostasis; Dissipating blood stasis for subsidence of swelling.Main haematemesis; Epistaxis; Hematuria; Metrorrhagia; Carbuncle sore tumefacting virus.[usage and dosage] is for oral administration: decoct soup, 3-9g.
Herba Biondiae henryi [source] medical material Ji Yuan: be the whole herb with root of Asclepiadaceae plant Green Dragon rattan.Latin plant animal mineral name: Biondia hnryi (Warb.Ex Schltr.Et Diels) Tsiang et P.T.Li[Cynanchum henryi Warb.Ex Schltr.EtDiels] to gather and store: all can adopt the whole year, using fresh herb or dry.[nature and flavor] are micro-pungent; Warm in nature.[return through] liver; Kidney channel.[function cures mainly] dispelling wind and removing obstruction in the collateral; Promoting blood circulation and stopping pain.Main anemofrigid-damp arthralgia; Numb limbs and tense tendons cold type of pain; Toothache; Traumatic injury.[usage and dosage] is for oral administration: decoct soup, 9～30g.
Evergreen chinquapin Folium Castaneae [source] medical material Ji Yuan: be the leaf of Fagaceae Guilin evergreen chinquapin.Latin plant animal mineral name: Castanopsis chinensis Hance gathers and stores: spring, summer, autumn all can pluck, using fresh herb or dry.[nature and flavor] hardship; Puckery; Property is put down.[function cures mainly] heat clearing and damp drying; Relieving diarrhea with astringents.Main diarrhea due to damp-heat.[usage and dosage] is for oral administration: decoct soup, 15-30g.
Folium zelkovae schneiderianae [source] medical material Ji Yuan: be the leaf of Ulmaceae beech tree.Latin plant animal mineral name: Zelkova schneideriana Hand.-Mazz. gathers and stores: summer, autumn gather, using fresh herb or dry.[nature and flavor] hardship; Cold in nature.[function cures mainly] heat-clearing and toxic substances removing; Removing heat from blood.Main skin infection swells and ache; Metrorrhagia leukorrhagia.[usage and dosage] is for oral administration: decoct soup, 6-10g.External: appropriate, smash deposited.
Muntjac grass [source] medical material Ji Yuan: be the herb of Huperziaceae plant Phlegmariurus fordii (Bak) Ching-Bak.Latin plant animal mineral name: Phlegmariurus fordii (Bak.) Ching[Lycopodium fordii Bak.] gather and store: the herb of gathering at the beginning of late summer, autumn, remove impurity, earth, dry.[nature and flavor] hardship; Cool.[function cures mainly] dispelling wind and removing obstruction in the collateral; Reducing swelling and alleviating pain; Heat-clearing and toxic substances removing.Main joint swells and ache; Numb limbs and tense tendons; Traumatic injury; Cough with asthma; Pyretic stranguria; Venom.[usage and dosage] is for oral administration: decoct soup, 3-9g; Or infusing drugs in wine.External: appropriate, smash deposited.
Wide lip Hyssopus officinalis [source] medical material Ji Yuan: be the herb of the wide lip Hyssopus officinalis of labiate.Latin plant animal mineral name: Hyssopus latilabiatus C.Y.Wu et H.W.Li gathers and stores: the 8-9 month gathers, and dries.[nature and flavor] acrid in the mouth; Cool in nature.[function cures mainly] clearing away heat and expelling pathogen in the exterior; Cough-relieving.Main flu; Cough.[usage and dosage] is for oral administration: decoct soup, 3-9g.
Radix potentillae anserinae grass [source] medical material Ji Yuan: be the herb of rosaceous plant Radix potentillae anserinae.Latin plant animal mineral name: Potentilla anserina L. gathers and stores: summer, autumn are excavated herb, remove impurity, are beaten up and dry.[nature and flavor] sweet in the mouth; Bitter; Cool in nature.Blood on [function cures mainly] removing heat from blood; Detoxification and promoting urination.Main various hemorrhage dysentery; The skin infection furuncle and phyma of having loose bowels.[usage and dosage] is for oral administration: decoct soup, 15-30g.
Lombardy poplar [source] medical material Ji Yuan: be bark or the leaf of Salicaceous Plants lombardy poplar.Latin plant animal mineral name: Populus nigra L var.thevestina (Dode) Bean[P.thevestina Dode] to gather and store: autumn, winter are adopted bark, dry; Picking leaves in summer, using fresh herb.[nature and flavor] hardship; Cold in nature.[function cures mainly] expelling wind and removing dampness; Removing pathogenic heat from blood and toxic substance from the body.Main air pain of dampness syndrome; Beriberi is swollen; Hepatitis; Dysentery; Burn and scald; Scabies tinea alba.[usage and dosage] is for oral administration: decoct soup, 10-15g.
Drymoglossum subcordatum [source] medical material Ji Yuan: be the herb of contrayerva Drymoglossum subcordatum.Latin plant animal mineral name: Pilea peperomioides Diels[Podophyllum cavaleriei Levl.] to gather and store: all can gather the whole year, cleans using fresh herb or dry.[nature and flavor] micro-hardship; Pungent; Cold in nature.[function cures mainly] heat-clearing and toxic substances removing; Removing blood stasis to reduce swelling.Main erysipelas; Fracture.[usage and dosage] is for oral administration: decoct soup, 6-9g.External: appropriate, smash deposited.
Arrow cutter grass [source] medical material Ji Yuan: for feverfew is stung the root of luxuriant Herba Vernonia esculenta.Latin plant animal mineral name: Vernonia squarrosa (D.Don) Less.[Acilepis squarrosa D.Don; Vernonia teres Mall.Ex DC.] to gather and store: all can excavate the whole year, cleans section, dries or using fresh herb.[nature and flavor] bitter in the mouth; Pungent; Cold nature.[function cures mainly] strengthening the spleen to promote digestion; Dehumidifying; Pain relieving.Main dyspepsia wind; Rheumatic arthritis; Migraine; Furuncle.[usage and dosage] is for oral administration: decoct soup, 9-30g; Levigation, each 3-6g, every day 2-3 time.External: appropriate, fresh goods is smash deposited.
Radix Polygoni Perfoliati [source] medical material Ji Yuan: be the root of polygonaceae plant Herba Polygoni Perfoliati.Latin plant animal mineral name: Polygonum perfoliatum L. gathers and stores: excavate root summer, Ex-all earth, using fresh herb or dry.[nature and flavor] acid; Bitter; Property is put down.[function cures mainly] removing toxic substances and promoting subsidence of swelling.Main boil on the nape opposite the mouth; Hemorrhoid; Anal fistula.[usage and dosage] is for oral administration: decoct soup, 9-15g; Fresh goods 15-30g.External: appropriate, smash deposited.
Kunming Flos seu Radix Impatientis nolitangeris [source] medical material Ji Yuan: be the herb of Balsaminaceae plant I.uliginosa.Latin plant animal mineral name: Impetiens uliginosa Franch. gathers and stores: summer, autumn gather, cleans, using fresh herb or dry.[nature and flavor] acrid in the mouth; Micro-hardship; Cold in nature; Mild toxicity.[return through] Liver Channel.[function cures mainly] removing damp-heat; Promoting blood circulation and detoxication.Main air damp-heat arthralgia; Traumatic injury; Amenorrhea; Dysmenorrhea; Dysphagic; Eczema scrotum; Mange skin ulcer tinea.[usage and dosage] is for oral administration: decoct soup, 9-15g.External: appropriate, decoct soup and wash; Or fresh goods is smash deposited.
Herba Phlomidis Tuberosae [source] medical material Ji Yuan: be root or the herb of labiate Phlomis kawaguchii Murata.Latin plant animal mineral name: Phlomis tuberosaL.[Phlomoides tuberosa Moench] to gather and store: gather summer, cleans, and dries [nature and flavor] mildly bitter flavor; Property is put down.[function cures mainly] removing toxic substances and promoting subsidence of swelling; The main finance and economics of invigorating blood circulation.Main prunus mume (sieb.) sieb.et zucc. poison; Skin ulcer is swollen; Menoxenia.[usage and dosage] is for oral administration: decoct soup, 3-6g.External: appropriate, smash and apply or grind into powder and spread.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of pityriasis rubra pilaris, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing pityriasis rubra pilaris.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of pityriasis rubra pilaris, it is characterized in that, by the medical material of following weight proportion, be prepared from: 10 parts of Herba lychnidis senno, 15 parts of the false Hepar Bovis seu Bubali of empty handle, 14 parts of Fructus Seu Folium Kopsiae Officinalis, 10 parts of green pepper Artemisias, 5 parts of Cirsium soulieis, 14 parts of Herba Biondiae henryi, 10 parts of evergreen chinquapin Folium Castaneae, 8 parts of Folium zelkovae schneiderianae, 6 parts of muntjac grass, 8 parts of wide lip Hyssopus officinalis, 12 parts of Radix potentillae anserinae grass, 12 parts of lombardy poplars, 10 parts of Drymoglossum subcordatums, 8 parts of arrow cutter grass, 20 parts of Radix Polygoni Perfoliatis, 10 parts of Kunming Flos seu Radix Impatientis nolitangeriss, 6 parts of Herba Phlomidis Tuberosaes.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
Inventor collects the out-patient of 60 routine pityriasis rubra pilaris for 2009 altogether between year December of July-2011, male 37 examples wherein, female's 23 examples, age 26-55 year, the course of disease 2 months-3 years.By random table, be divided at random: treatment group 30 examples, blank group 30 examples.The data there was no significant differences such as two groups of ages, the state of an illness, have comparability.
2, test method
The capsule that the oral the present invention of 2.1 treatment group makes according to specific embodiment 1, sooner or later respectively once.The January course for the treatment of.
2.2 blank group oral placebo capsules, sooner or later respectively once.The January course for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: deflorescence is more than 90%, and subjective symptoms disappears.Effective: deflorescence >=60%, subjective symptoms disappears substantially.Taking a turn for the better: clinical symptoms disappears >=and 30%, subjective symptoms disappears.Invalid: the pustule < 30% or unchanged that disappears, clinical symptoms is not improved even and increases the weight of.
3.2 treatment statistical results are in Table 1.
Table 1 liang group curative effect comparison
| Group | n | Recovery from illness | Effective | Take a turn for the better | Invalid | Untoward reaction example | Total effective rate (%) |
| Treatment group | 30 | 3(10％) | 9(30％) | 14(46.7％) | 4(13.3％) | 0 | 86.7％ |
| Blank group | 30 | 0 | 0 | 3(10％) | 27(90％) | 0 | 10％ |
Visible, the medicine that the present invention makes can safe and effective treatment pityriasis rubra pilaris.
The specific embodiment
In order to understand better and to implement the present invention, below in conjunction with specific embodiment, further illustrate the present invention.
Specific embodiment 1
Take: 10 grams of Herba lychnidis senno, 15 grams of the false Hepar Bovis seu Bubali of empty handle, 14 grams of Fructus Seu Folium Kopsiae Officinalis, 10 grams of green pepper Artemisias, 5 grams of Cirsium soulieis, 14 grams of Herba Biondiae henryi, 10 grams of evergreen chinquapin Folium Castaneae, 8 grams of Folium zelkovae schneiderianae, 6 grams of muntjac grass, 8 grams of wide lip Hyssopus officinalis, 12 grams of Radix potentillae anserinae grass, 12 grams of lombardy poplars, 10 grams of Drymoglossum subcordatums, 8 grams of arrow cutter grass, 20 grams of Radix Polygoni Perfoliatis, 10 grams of Kunming Flos seu Radix Impatientis nolitangeriss, 6 grams of Herba Phlomidis Tuberosaes, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, must meet the capsule of 1 day consumption of normal adult.
Be used for the treatment of pityriasis rubra pilaris.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take: 10 grams of Herba lychnidis senno, 15 grams of the false Hepar Bovis seu Bubali of empty handle, 14 grams of Fructus Seu Folium Kopsiae Officinalis, 10 grams of green pepper Artemisias, 5 grams of Cirsium soulieis, 14 grams of Herba Biondiae henryi, 10 grams of evergreen chinquapin Folium Castaneae, 8 grams of Folium zelkovae schneiderianae, 6 grams of muntjac grass, 8 grams of wide lip Hyssopus officinalis, 12 grams of Radix potentillae anserinae grass, 12 grams of lombardy poplars, 10 grams of Drymoglossum subcordatums, 8 grams of arrow cutter grass, 20 grams of Radix Polygoni Perfoliatis, 10 grams of Kunming Flos seu Radix Impatientis nolitangeriss, 6 grams of Herba Phlomidis Tuberosaes, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, must meet the powder of 1 day consumption of normal adult.
Be used for the treatment of pityriasis rubra pilaris.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take: 10 grams of Herba lychnidis senno, 15 grams of the false Hepar Bovis seu Bubali of empty handle, 14 grams of Fructus Seu Folium Kopsiae Officinalis, 10 grams of green pepper Artemisias, 5 grams of Cirsium soulieis, 14 grams of Herba Biondiae henryi, 10 grams of evergreen chinquapin Folium Castaneae, 8 grams of Folium zelkovae schneiderianae, 6 grams of muntjac grass, 8 grams of wide lip Hyssopus officinalis, 12 grams of Radix potentillae anserinae grass, 12 grams of lombardy poplars, 10 grams of Drymoglossum subcordatums, 8 grams of arrow cutter grass, 20 grams of Radix Polygoni Perfoliatis, 10 grams of Kunming Flos seu Radix Impatientis nolitangeriss, 6 grams of Herba Phlomidis Tuberosaes, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, and according to this area common process, to granulate, packing, can make the granule that meets 1 day consumption of normal adult.
Be used for the treatment of pityriasis rubra pilaris.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. a Chinese medicine for the treatment of pityriasis rubra pilaris, it is characterized in that, by the medical material of following weight proportion, be prepared from: 10 parts of Herba lychnidis senno, 15 parts of the false Hepar Bovis seu Bubali of empty handle, 14 parts of Fructus Seu Folium Kopsiae Officinalis, 10 parts of green pepper Artemisias, 5 parts of Cirsium soulieis, 14 parts of Herba Biondiae henryi, 10 parts of evergreen chinquapin Folium Castaneae, 8 parts of Folium zelkovae schneiderianae, 6 parts of muntjac grass, 8 parts of wide lip Hyssopus officinalis, 12 parts of Radix potentillae anserinae grass, 12 parts of lombardy poplars, 10 parts of Drymoglossum subcordatums, 8 parts of arrow cutter grass, 20 parts of Radix Polygoni Perfoliatis, 10 parts of Kunming Flos seu Radix Impatientis nolitangeriss, 6 parts of Herba Phlomidis Tuberosaes.
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| CN103520397A (en) * | 2013-10-31 | 2014-01-22 | 刘青云 | Traditional Chinese medicine for treating pityriasis rubra pilaris |
| CN103536788A (en) * | 2013-10-11 | 2014-01-29 | 陈永泉 | Traditional Chinese medicine for treating pityriasis rubra pilaris |
| CN103655715A (en) * | 2013-12-12 | 2014-03-26 | 黄根强 | Traditional Chinese medicine for treating pityriasis rubra pilaris |
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| CN103536788A (en) * | 2013-10-11 | 2014-01-29 | 陈永泉 | Traditional Chinese medicine for treating pityriasis rubra pilaris |
| CN103520397A (en) * | 2013-10-31 | 2014-01-22 | 刘青云 | Traditional Chinese medicine for treating pityriasis rubra pilaris |
| CN103655715A (en) * | 2013-12-12 | 2014-03-26 | 黄根强 | Traditional Chinese medicine for treating pityriasis rubra pilaris |
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