Background technology
Chronic mediastinitis is also known as idiopathic fibrosis of mediastinum, and the cause of disease is more complicated.Chronic mediastinitis can cause obstruction of superior vena cava, and a series of obstruction of superior vena cava symptom and sign appears in patient.Usual earlier is asymptomatic, but can engender the symptom of mediastinum organ adhesion or pressurized, is mainly obstruction of superior vena cava syndrome, occurs that venous pressure increases, Head And Face, cervical region and edema of the upper extremity, jugular vein fill, Doppler flow mapping venectasia on thoracic wall.
The effective medicine of generally recognized as safe is still lacked at present for chronic mediastinitis.
Involved by Chinese medicine of the present invention, the present Research of medical material is as follows:
Radix Ervatamiae Hainanensis [source] Bignoniaceae Incarvillea AJuss plant Herba Melicae Scabrosae Incarvilleaarguta (Royle) Royle[function cures mainly] expelling wind and removing dampness, anti-inflammatory analgetic, promoting blood circulation to remove blood stasis.For rheumatic ostalgia, menoxenia; Furuncle is controlled in external, carbuncle, fracture.
Herba Clerodendri fortunati [source] remits paulownia platymiscium Herba Clerodendri fortunati for Herba Verbenae., be used as medicine with root or Herb.The whole year can adopt, and clean, section is dried.[function cures mainly] heat-clearing and toxic substances removing, cough-relieving analgesic therapy.For cold, fever, pharyngolaryngitis, bronchitis, pulmonary tuberculosis hectic fever, stomachache, colic; Traumatic injury, furuncle furuncle and phyma.
The large Herba Lobeliae Chinensis of large Herba Lobeliae Chinensis [source] Scrophulariaceae Herba Lobeliae Chinensis platymiscium is with all herbal medicine.Xia Qiu gathers, and chopping, dries.[function cures mainly] strengthening the spleen to promote digestion, clearing away heat-damp and promoting diuresis.For infantile malnutrition, inappetence, urinary tract infection, icterohepatitis.
Xinjiang Herba Achilleae [source] Compositae mugwort Herba Artemisiae Brachylobae, with all herbal medicine.Xia Qiucai herb, dries.[function cures mainly] heat-clearing and toxic substances removing.For stomachache, flatulence, dysmenorrhea; Bleeding hemorrhoids is controlled in external, innominate toxic swelling, traumatic injury, venom, urticaria, neurodermatitis.
Mucuna paohwashanica Tang et Wang [source] pulse family Mucuna plant Mucuna paohwashanica Tang et Wang, is used as medicine with root.Many using fresh herbs.[function cures mainly] promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain.For treating swelling and pain by traumatic injury, fracture, carbuncle furuncle.
Rhizoma sagittariae sagittifoliae [source] Alismataceae Rhizoma sagittariae sagittifoliae platymiscium is kind, with bulb and all herbal medicine.Autumn gathers, and cleans and dries.[function cures mainly] clearing away heat to stop bleeding, removing toxic substances and promoting subsidence of swelling, eliminating stagnation.For spitting of blood, spit blood, difficult labour, retention of placenta in puerperal, bleeding not during menses, lithangiuria, infantile erysipelas; Carbuncle sore tumefacting virus is controlled in external, venom.
Ginger precipice, precipice Rhizoma Zingiberis Recens [source] fern Polypodiaceae precipice Rhizoma Zingiberis Recens, is used as medicine with root stock.Spring and summer gathers, unhairing, cleans section, dries.[function cures mainly] expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral.For rheumatalgia, traumatic injury, fracture, otitis media.
Fructus Ailanthi [source] this product is the fruit of quassia ailanthus altissima (mill.) swingle.Autumn Mo fruit picking, dries.[function cures mainly] clearing away heat and promoting diuresis, pain relieving, hemostasis.For stomachache, have blood in stool, hematuria; Trichomonas vaginitis is controlled in external.
The seed of seed of Hygrophila saxatilis Ridl. [source] Acanthaceae Hygrophila phytolith Hygrophila salicifolia.The pain relieving of [function cures mainly] spasmolytic.For demented, twitch, asthma, stomachache.Carbuncle is controlled in external, malignant boil.
Thorn coriander [source] Umbelliferae thorn coriander platymiscium thorn coriander, with all herbal medicine.Xia Qiucai, dries in the shade or using fresh herb.[function cures mainly] dispelling wind is antipyretic, stomach invigorating.For flu, measles is caved in, tracheitis, enteritis, diarrhoea, acute infectious hepatitis; Treating swelling and pain by traumatic injury is controlled in external.
Water-bed dragon [source] Araeceae thrum Calamus plant thrum rattan, is used as medicine with Herb.The whole year can adopt, and using fresh herb or section are dried.[function cures mainly] promoting blood circulation to remove blood stasis, heat-clearing and toxic substances removing, cough-relieving, pain relieving.For traumatic injury, stomachache, stomachache, bronchitis, pertussis; Fracture is controlled in external, and thorn of bee or insect is stung, venom, burn and scald.
Ginseng of riding [source] the orchid family Platanthera plant tongue lip is blue, is used as medicine with whole herb with root.Summer excavates, and cleans, dries.[function cures mainly] lung moistening, expelling phlegm for arresting cough.For cough due to lung-heat, breath with cough.
Poison root Herba Vernonia esculenta [source] ironweed plant poison root Herba Vernonia esculenta, is used as medicine with rattan or root.The four seasons can adopt, and clean section, dry.[function cures mainly] expelling pathogenic wind from the body surface, relaxing muscles and tendons and activating QI and blood in the collateral, preventing the attack (or recurrence) of malaria.For rheumatic arthritis, lumbago and skelalgia, traumatic injury, malaria; Eye conjunctivitis is controlled in external.
The seed of Semen Gossypii [source] Malvaceae cotton cotton, tree cotton (Chinese cotton) and Gossypium hirsutum L. (highland is cotton).Xia Qiu gathers, and dries.[function cures mainly] invigorating the liver and kidney, strong waist knee joint, warming the stomach pain relieving, hemostasis, lactogenic.For menorrhagia, dysfunctional uterine hemorrhage, agalactosis, stomachache, weakness of the waist and knees.
Radix ceratostigmatis willemottiani [source] lumbaginaceae Ceratostigma platymiscium Radix ceratostigmatis willemottiani and ceratostigma plumbaginoides Bunge C.plumbaginoidesBunge, be used as medicine with root.Xia Qiu gathers, and dries.[function cures mainly] spasmolytic, analgesia.For gastritis, gastric ulcer, ascariasis of biliary tract, the pain that cholecystitis and ascariasis cause.
The Radix Paeoniae Alba [source] is the root of dicotyledon medicine ranunculaceae plant Radix Paeoniae (cultigen).The Peony Root of having planted 3 ~ 4 years, removing rhizome and fibrous root, clean, scrape off rough bark, enter in boiling water and slightly boil, Chinese herbaceous peony root is felt like jelly, pulls out and dry.[function cures mainly] nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
Poria [source] colonizes in the fungi plant on pinaster root, and shape is as Rhizoma Dioscoreae esculentae, and its protozoa is the dry sclerotia of On Polyporaceae Poria, and multiparasitization is in the root of Pinus massoniana Lamb or Pinus densiflora.[function cures mainly] sweet in the mouth, light, property are put down, and are used as medicine and have the function of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.
The evergreen climing property shrub of Fructus Rosae Laevigatae [source], obtains through refining tannic extract without Rhizoma Imperatae skin; Fruit medicine.[function cures mainly] relieving cough and asthma, spasmolytic, has diuresis, kidney tonifying functions; Anti-inflammation, blood fat reducing.Leaf has removing toxic substances and promoting subsidence of swelling effect; Root is medicinal, can promoting blood circulation to remove blood stasis, convergence of drawing out pus by applying a plaster to the affected part, dispel the wind that it is wet to drive.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of chronic mediastinitis, by selecting suitable medical material and proportioning thereof, reaches the object of the chronic mediastinitis of safe and effective healing.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of chronic mediastinitis, it is characterized in that, be prepared from by the medical material of following weight proportion: Radix Ervatamiae Hainanensis 15 parts, Herba Clerodendri fortunati 12 parts, large Herba Lobeliae Chinensis 14 parts, Xinjiang Herba Achilleae 8 parts, Mucuna paohwashanica Tang et Wang 10 parts, Rhizoma sagittariae sagittifoliae 12 parts, precipice Rhizoma Zingiberis Recens 12 parts, Fructus Ailanthi 14 parts, seed of Hygrophila saxatilis Ridl. 10 parts, thorn coriander 12 parts, water-bed dragon 14 parts, ginseng of riding 12 parts, malicious root Herba Vernonia esculenta 10 parts, Semen Gossypii 12 parts, Radix ceratostigmatis willemottiani 14 parts, the Radix Paeoniae Alba 10 parts, 12 parts, Poria, Fructus Rosae Laevigatae 14 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects the out-patient of 80 routine chronic mediastinitiss altogether between in February ,-2012 in March, 2009, age 20-55 year, course of disease 0.5-5.Be divided at random: treatment group 60 example, blank group 20 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2, test method
The capsule that the oral the present invention of 2.1 treatment group obtains according to specific embodiment 1, sooner or later respectively once.15 days courses for the treatment of.
2.2 blank group oral placebo capsules, sooner or later respectively once.15 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and test chamber inspection is normal.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, lab testing improvement or normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
Group |
n |
Recovery from illness |
Take a turn for the better |
Invalid |
Untoward reaction example |
Total effective rate (%) |
Treatment group |
60 |
15(25%) |
34(56.7%) |
11(18.3%) |
0 |
81.7% |
Blank group |
20 |
0 |
5(25%) |
15(75%) |
0 |
25% |
Visible, the medicine that the present invention obtains safe and effectively can control chronic mediastinitis.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Radix Ervatamiae Hainanensis 15 grams, Herba Clerodendri fortunati 12 grams, large Herba Lobeliae Chinensis 14 grams, Xinjiang Herba Achilleae 8 grams, Mucuna paohwashanica Tang et Wang 10 grams, Rhizoma sagittariae sagittifoliae 12 grams, precipice Rhizoma Zingiberis Recens 12 grams, Fructus Ailanthi 14 grams, seed of Hygrophila saxatilis Ridl. 10 grams, thorn coriander 12 grams, water-bed dragon 14 grams, ginseng of riding 12 grams, malicious root Herba Vernonia esculenta 10 grams, Semen Gossypii 12 grams, Radix ceratostigmatis willemottiani 14 grams, the Radix Paeoniae Alba 10 grams, 12 grams, Poria, Fructus Rosae Laevigatae 14 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.
Be used for the treatment of chronic mediastinitis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take: Radix Ervatamiae Hainanensis 15 grams, Herba Clerodendri fortunati 12 grams, large Herba Lobeliae Chinensis 14 grams, Xinjiang Herba Achilleae 8 grams, Mucuna paohwashanica Tang et Wang 10 grams, Rhizoma sagittariae sagittifoliae 12 grams, precipice Rhizoma Zingiberis Recens 12 grams, Fructus Ailanthi 14 grams, seed of Hygrophila saxatilis Ridl. 10 grams, thorn coriander 12 grams, water-bed dragon 14 grams, ginseng of riding 12 grams, malicious root Herba Vernonia esculenta 10 grams, Semen Gossypii 12 grams, Radix ceratostigmatis willemottiani 14 grams, the Radix Paeoniae Alba 10 grams, 12 grams, Poria, Fructus Rosae Laevigatae 14 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, the powder of adult normal's 1 day consumption must be met.
Be used for the treatment of chronic mediastinitis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take: Radix Ervatamiae Hainanensis 15 grams, Herba Clerodendri fortunati 12 grams, large Herba Lobeliae Chinensis 14 grams, Xinjiang Herba Achilleae 8 grams, Mucuna paohwashanica Tang et Wang 10 grams, Rhizoma sagittariae sagittifoliae 12 grams, precipice Rhizoma Zingiberis Recens 12 grams, Fructus Ailanthi 14 grams, seed of Hygrophila saxatilis Ridl. 10 grams, thorn coriander 12 grams, water-bed dragon 14 grams, ginseng of riding 12 grams, malicious root Herba Vernonia esculenta 10 grams, Semen Gossypii 12 grams, Radix ceratostigmatis willemottiani 14 grams, the Radix Paeoniae Alba 10 grams, 12 grams, Poria, Fructus Rosae Laevigatae 14 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, granulate according to this area common process, packaging, can obtain the granule meeting adult normal's 1 day consumption.
Be used for the treatment of chronic mediastinitis.Oral, every bu is taken for twice sooner or later.