Background technology
Insomnia be take that difficulty falling asleep, early awakening, the length of one's sleep are not enough, Depth of sleep not and can not allaying tiredness, regain one's strength and the energy disease that is principal character, the Qi Shu motherland medical science categories such as " insomnia " of " being insomnia ".Along with the aging process of population, old people's insomnia problem also more and more comes into one's own.Old people's self function decline, often take the hepatic and renal YIN deficiency, excessive rising of liver-YANG is Etiological pathogenesis.
Medical material present Research involved in the present invention is as follows:
Cortex Albiziae [source] this product is the dry bark of leguminous plant Herba Albiziae Albizia julibrissin Durazz..Summer, Qiu Erji strip, and dry.[character] this product is curling tubular or half tubular, long 40~80cm, thick 0.1~0.3cm.Outer surface taupe brown, to taupe, is slightly indulged wrinkle, some one-tenth checkings, and close life is oval laterally hole skin significantly, brown or brownish red, even bossed horizontal rib or larger circle branch trace, often with lichens speckle; Fallow or the yellow-white of inner surface, level and smooth, there is fine and closely woven longitudinal grin.Matter is hard and crisp, frangibility, and section is fibroid lamellar, fallow or yellow-white.Feeble QI is fragrant, lightly seasoned, micro-puckery, slightly sting tongue, then larynx has sense of discomfort.[process of preparing Chinese medicine] removes impurity, cleans, run through, and shredding or piece, dry.[nature and flavor] are sweet, flat.1. < < herbal classic > >: " sweet, flat." 2. < < book on Chinese herbal medicine converges and says > >: " is sweet, Wen Ping." [return through] enters the heart, Liver Channel.1. < < Thunder God is concocted property of medicine solution > >: " enter heart channel." 2. < < book on Chinese herbal medicine newer > >: " enters the heart, liver two warps." [function cures mainly] resolving depression, and blood, mind calming, subduing inflammation.Control irritability, melancholy insomnia, lung abscess, carbuncle, scrofula, injured bone.1. < < herbal classic > >: " main settling five organs, and will make us happy carefree." 2. < < Bencao Shiyi > >: " parasite killing." 3. < < Japan hanako materia medica > >: " soft extracts, subduing inflammation reuniting the fractured tendons and bones." 4. < < detailed outline > >: " and blood, detumescence, pain relieving." 5. < < classification medical herbs > >: " scrofula disappears." 6. < < animals and plants medicine > among the people >: " controls cough." 7. Nanchuan < < conventional Chinese herbal medicine handbook > >: " controls that the motive is restless, insomnia and clonic spasm of the muscle.[usage and dosage] 6~12g.Suitable amount used externally, grinds into powder and dresses.
Fructus Evodiae [another name] Fructus Evodiae, tea are peppery, spicy, smelly spicy, Wu green pepper, smelly lake [source] this product are rutaceae Fructus Evodiae Evodia rutaecarpa (Juss.) Benth., Shi Hu Evodia rutaecarpa (Juss.) Benth.var.officinalis (Dode) Huang or a dry almost ripe fruit of dredging hair Fructus Evodiae Evodia rutaecarpa (Juss.) Benth.var.bodinieri (Dode) Huang.When 8~November, fruit not yet ftractureed, cut Fruit branch, dry or cold drying, except impurity such as debranching, leaf, carpopodiums.[nature and flavor] are arduous, and temperature is poisonous.1. < < herbal classic > >: " acrid in the mouth, temperature." 2. < < does not record > >: " is hot greatly, slightly poisonous." 3. < < property of medicine opinion > >: " bitter in the mouth is pungent, hot greatly, poisonous." [return through] enters liver, stomach warp.1. < < Decoction and Material Medica > >: " enter lunar, few cloudy, the JUE YIN meridian of foot." 2. < < Thunder God is concocted property of medicine solution > >: " enters liver, spleen, stomach, large intestine, kidney channel." [function cures mainly] warming middle-JIAO, pain relieving, regulates the flow of vital energy, dampness, stopping vomiting is against acid regurgitation, headache due to JUE YIN disorder, the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, abdominal pain during menstruation, Diarrhoea, vascular hypertension, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.1. < < herbal classic > >: " main warming the middle warmer and descending qi, pain relieving, cough with dyspnea cold and heat, dehumidifying arthralgia due to stagnation of blood, by ailment said due to cold or exposure, loosing the interspaces of skin and muscles." 2. < < does not record > >: " main expectorant is cold, angor in abdomen, and Zhu Lengshi does not disappear, attacked by pestiferous factors, cardiac and abdominal pain, contrary gas, sharp the five internal organs." 3. < < property of medicine opinion > >: " main trusted subordinate's disease, accumulation of pathogenic cold, stagnation of QI under the heart, chronic infectious disease is pained; Control cramp caused by acute vomiting and diarrhea, cold in the stomach gas, the stomachache of vomiting and diarrhoea can not win the person of bearing; Treat insensitive impediment all over, cold drinks and snachs does not disappear, and sharp large intestine is gathered around gas." 4. < < Bencao Shiyi > >: " kills evil insect poison, and tooth worm is hidden." 5. < < Japan hanako materia medica > >: " spleen invigorating is got round by bribery.Control stomachache, kidney qi, beriberi, edema, lower puerperal remaining blood." 6. Wang Haogu: " controls feeling of fullness plug breast, and pharynx diaphragm is obstructed, the dry spleen of profit liver." 7. < < detailed outline > >: " dissipating depression of QIization is stagnant.Control acid regurgitation, the cloudy sputum headache of falling, insidious stomachache, hernia, dysentery, mouthpiece's aphtha." [usage and dosage] is for oral administration: decoct soup, 0.5~2 money; Or enter ball, loose.External: steaming is pressed, grinds into powder and dresses or decoct washing.[attention] hyperactivity of fire caused by deficiency of YIN person avoids clothes.1. < < Collective Notes to Canon of Materia Medica > >: " Fructus polygoni hydropiperis makes for it.Dislike Radix Salviae Miltiorrhizae, Sal Nitri, Chalk, fear Fluoritum." 2. < < book on Chinese herbal medicine covers bamboo fish trap > >: " intestinal diarrhea due to deficiency person avoid especially." 3. < < detailed outline > >: " is flat, gets angry, and confused order, sends out skin ulcer." 4. < < Bencao Jingshu > >: " vomiting acid regurgitation belongs to stomach-fire person and should not use; Cough with dyspnea, person should not use due to non-wind and cold exopathogen and cold phlegm retained water; Stomachache belongs to blood deficiency has fiery person to use; Red white dysentery, because pathogenic summer-heat enters the intestines and stomach, should not use but not food and drink is raw and cold, stagnate dirty person; Inguinal hernia, non-rapid sense cold-evil and onset should not be used; Cramp caused by acute vomiting and diarrhea, due to weakness of the spleen and stomach affection caused by summer-heat, but not cold-damp raw food should not be used in violating the intestines and stomach person; The card of all deficiency of YIN and the vital organs of the human body have heat without cold people, and method institute is salty to be avoided.
Flos Jasmini Sambac [source] Oleaceae Flos Jasmini Sambac platymiscium jasmine Jasminum sambac (L.) Aiton, is used as medicine with root and flower.Uproot, section is dried after autumn; Xia Qiu picks flowers, and dries.[nature and flavor] acrid, sweet, cool.Root is poisonous.[function cures mainly] flower, leaf: clearing away heat and expelling pathogen in the exterior, dampness removing.For fever caused by exogenous pathogens, diarrhoea; Conjunctival congestion and swelling pain is controlled in flower external.Root: analgesia.For insomnia, traumatic injury.[usage and dosage] spent, leaf 1~2 money, and flower suitable amount used externally is decocted washing eye.Root 1~2 money, suitable amount used externally, mashes deposited affected part.[extracts] < < whole nation Chinese herbal medicine compilation > >.
Rhodobryum roseum Limpr. [another name] Rhodobryum giganteum, fennel firewood grass, ferrum foot Rhizoma Arisaematis, warm ground of Rhodobryum giganteum(Hook.) Par. [source] moss Bryaceae rhodobryum spp plant great Ye moss Rhodobryum giganteum (Schwaegr.) Par., with all herbal medicine.Can adopt the whole year, using fresh herb or dry in the shade.[nature and flavor] are pungent, bitter, flat.[function cures mainly] tranquilizing by nourishing the heart, liver heat removing and eyesight improving.For severe palpitation, neurasthenia; Conjunctival congestion and swelling pain is controlled in external.[usage and dosage] 1~3 money; Suitable amount used externally, decocts water smoking and washes.
Radix anthrisci [source] Umbelliferae Anthriscus plant Radix anthrisci Anthriscus sylvestris (L.) Hoffm., is used as medicine with root, leaf.During the flavescence of 8~JIUYUE aerial parts, uproot, clean and boil, go crust to dry or dry; Leaf using fresh herb or dry levigation.[nature and flavor] sweet, pungent, micro-hardship, tepor.[function cures mainly] invigorating the spleen and replenishing QI, promoting tissue regeneration by removing blood stasis.Root: for traumatic injury, lumbago, cough due to deficiency of the lung, cough spitting of blood, splenasthenic abdominal distention, myasthenia of limbs, senile frequent micturition, edema; Leaf: wound [usage and dosage] root 4~5 money are controlled in external; Leaf suitable amount used externally, fresh leaf is mashed or cured leaf levigation applies affected part [extracts] < < whole nation Chinese herbal medicine compilation > >.
The Preparation process product that Radix Astragali Preparata [source] this product is the Radix Astragali.[character] this product is circular or oval-shaped, diameter 0.8~3.5cm, thick 0.1~0.4cm.The shallow pale brown or sepia of exocuticle, slightly glossy, indulge as seen wrinkle or longitudinal furrow.Tangent plane skin zone is light yellow, and xylem is yellow, has radial texture and crack, and You center is even a dry and decayed shape, pitchy or be cavity.Tool honey fragrance, taste is sweet, stickiness slightly, that chews micro-ly has a beany flavor.[process of preparing Chinese medicine] gets astragalus mongholicus tablet, according to processed with honey method (appendix II D), fries to tack-free.[nature and flavor] are sweet, temperature.[return through] returns lung, spleen channel.The invigorating middle warmer of [function cures mainly] QI invigorating.Weak for the deficiency of vital energy, anorexia and loose stool.[usage and dosage] 9~30g.
Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L..Spring, Qiu Erji excavate, and remove fibrous root, dry.[process of preparing Chinese medicine] removes impurity, cleans, and runs through, and cuts sheet, dry.[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.[usage and dosage] 1.5~9g.[attention] should not be with Radix Euphorbiae Pekinensis, Flos Genkwa, Radix Kansui with using.[storage] puts aeration-drying place, mothproof.[extracts] < < Chinese Pharmacopoeia > >.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine that is used for the treatment of senile insomnia, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing senile insomnia.
In order to achieve the above object, the present invention is by the following technical solutions:
A Chinese medicine that is used for the treatment of senile insomnia, is characterized in that, it is that raw medicinal material by following weight proportion is prepared from: 6 parts of Cortex Albiziaes, 3 parts of Fructus Evodiaes, 6 parts of Flos Jasmini Sambacs, 8 parts of Rhodobryum roseum Limpr.s, 12 parts of Radix anthriscis, 15 parts of Radix Astragali Preparatas, 3 parts, Radix Glycyrrhizae.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
Inventor collects outpatient service insomniac 106 examples in JIUYUE, 2010~2013 altogether between year April.Man's 50 examples, female's 56 examples, age 65-84 year.Be divided at random treatment group 56 example and matched group 50 examples.Before two groups of sexes, age, the course of disease, treatment, the comparing difference not statistically significant such as symptom, has comparability.
Diagnostic criteria: 1, take and be insomnia as primary symptom, the lighter's difficulty of falling asleep or sleep but easy to wake, be insomnia after waking up, and severe one is lain awake all night; 2, often with cardiopalmus, dizziness, forgetful, dreaminess, the disease such as vexed; (3) often have eating and drinking without temperance, abnormal emotion, overstrain, excessive thinking, after being ill, the medical history such as body void.
2, test method
2.1 Therapeutic Method
The decoct that the oral the present invention of test group makes according to specific embodiment 1, every day 3 times.4 weeks courses for the treatment of.
1 of the oral estazolam of matched group, per os hora somni.4 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms, sign disappear completely;
Effective: clinical cardinal symptom, sign disappear substantially;
Effective: clinical cardinal symptom, sign alleviate;
Invalid: not reach above-mentioned effective standard or deterioration person.
3.2 therapeutic outcomes are in Table 1
Table 1 liang group clinical efficacy result comparison
Group |
n |
Recovery from illness |
Effective |
Effectively |
Invalid |
Total effective rate (%) |
Untoward reaction example |
Treatment group |
56 |
18 |
28 |
8 |
2 |
96.4% |
0 |
Matched group |
50 |
0 |
21 |
19 |
10 |
80% |
3 |
Result is visible, and Chinese medicine of the present invention can the safe and effective treatment for senile insomnia.
The specific embodiment
In order to understand better and to implement the present invention, below in conjunction with specific embodiment, further illustrate the present invention.
Specific embodiment 1
Take: 6 grams of Cortex Albiziaes, 3 grams of Fructus Evodiaes, 6 grams of Flos Jasmini Sambacs, 8 grams of Rhodobryum roseum Limpr.s, 12 grams of Radix anthriscis, 15 grams of Radix Astragali Preparatas, 3 grams, Radix Glycyrrhizae; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of one day consumption of normal adult.
Be used for the treatment of senile insomnia.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: 6 grams of Cortex Albiziaes, 3 grams of Fructus Evodiaes, 6 grams of Flos Jasmini Sambacs, 8 grams of Rhodobryum roseum Limpr.s, 12 grams of Radix anthriscis, 15 grams of Radix Astragali Preparatas, 3 grams, Radix Glycyrrhizae; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, pack, must meet the powder of one day consumption of normal adult.
Be used for the treatment of senile insomnia.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take: 6 grams of Cortex Albiziaes, 3 grams of Fructus Evodiaes, 6 grams of Flos Jasmini Sambacs, 8 grams of Rhodobryum roseum Limpr.s, 12 grams of Radix anthriscis, 15 grams of Radix Astragali Preparatas, 3 grams, Radix Glycyrrhizae; Add 6 times of water gagings, decoct 3 times, decoct 1 hour at every turn, merge decoction liquor, concentrated, then add appropriate dextrin and correctives, and according to this area common process, to granulate, packing, can make the granule that meets one day consumption of normal adult.
Be used for the treatment of senile insomnia.Oral, take once every day.