Background technology
Insomnia be with difficulty falling asleep, early awakening, the length of one's sleep deficiency, Depth of sleep not and can not eliminate fatigue,Regain one's strength and the energy disease that is principal character, the Qi Shu motherland medical science categories such as " must not sleep " of " being insomnia ".Along with the aging process of population, the elderly's insomnia problem also more and more comes into one's own. The elderly's selfFunction decline, often taking the deficiency of liver-yin and kidney-yin, liver-yang hyperactivity as the Etiological interpretation of the cause, onset and process of an illness.
Medicinal material present Research involved in the present invention is as follows:
Cortex albiziae [source] this product is the dry of legume silk tree AlbiziajulibrissinDurazz.Dry bark. Summer, Qiu Erji strip, and dry. [proterties] this product is curling tubular or half tubular, long by 40~80cm, thick 0.1~0.3cm. Outer surface taupe brown, to taupe, is slightly indulged wrinkle, some one-tenth checkings,Close life is oval laterally hole skin significantly, brown or brownish red, even bossed horizontal rib or larger circular branchTrace, often with lichens spot; Fallow or the yellow-white of inner surface, level and smooth, there is fine and closely woven longitudinal grin. Matter is hard and crisp,Frangibility, section is fibroid sheet, fallow or yellow-white. The micro-perfume (or spice) of gas, lightly seasoned, micro-puckery, slightly thornTongue, then larynx has sense of discomfort. [process of preparing Chinese medicine] removes impurity, cleans, run through, and chopping or piece, dry. [propertyTaste] sweet, flat. 1. " herbal classic ": " sweet, flat. " 2. " book on Chinese herbal medicine converges and says ": " is sweet, Wen Ping. " [returning through]Enter the heart, Liver Channel. 1. " Thunder God is concocted property of medicine solution ": " enter the heart channel of Hang-Shaoyin. " 2. " book on Chinese herbal medicine is new again ": " enters the heart, liver twoWarp. " [function cures mainly] Xie Yu, and blood, Ning Xin, subduing inflammation. Control confused and worried, melancholy insomnia, lungCarbuncle, carbuncle is swollen, scrofula, injured bone. 1. " herbal classic ": " main five viscera settling, and will make us happy carefree." 2. supplement to the Herbal: " desinsection. " 3. " Japan hanako materia medica ": " soft extracts, subduing inflammation continuous muscles and bones. " 4. " guiding principleOrder ": " and blood, detumescence, pain relieving. " 5. " classification herbal medicine ": " scrofula disappears. " 6. " animals and plants medicine among the people ":" control cough. " 7. Nanchuan " conventional Chinese herbal medicine handbook ": " controls that the motive is restless, insomnia and muscle contraction. [usage and dosage]6~12g. Suitable amount used externally, grinds into powder and dresses.
Evodia rutaecarpa [another name] Wu cornel, tea are peppery, spicy, smelly spicy, Wu green pepper, smelly lake [source] thisProduct are rutaceae evodia rutaecarpa Evodiarutaecarpa (Juss.) Benth., Shi Hu EvodiaRutaecarpa (Juss.) Benth.var.officinalis (Dode) Huang or a thin hair evodia rutaecarpaEvodiarutaecarpa (Juss.) Benth.var.bodinieri (Dode) Huang's is dryAlmost ripe fruit. When 8~November, fruit not yet ftractureed, cut fruit branch, dry or low temperature drying, except debranching,The impurity such as leaf, carpopodium. [nature and flavor] are arduous, and temperature is poisonous. 1. " herbal classic ": " taste is pungent, temperature. " 2. " otherRecord ": " hot greatly, slightly poisonous. " 3. " property of medicine opinion ": " bitter is pungent, hot greatly, poisonous. " [return through] enter liver,Stomach warp. 1. Materia Medica of Decoction: " enter lunar, few cloudy, the JUE YIN meridian of foot. " 2. " Thunder God is concocted property of medicine solution ": "Enter liver, spleen, stomach, large intestine, kidney channel. " in [function cures mainly] temperature, pain relieving, regulates the flow of vital energy, and eliminating dampness is controlled and vomittedContrary acid regurgitation, jueyin headache, the cold syndrome in infant is vomited and diarrhoea, abdominal distention, dysmenorrhea, Diarrhoea, vascular hypertension,Beriberi, hernia, aphthous ulcer, dentalgia, eczema, impetigo. 1. " herbal classic ": " main warming the middle warmer and descending qi, onlyBitterly, cough contrary fever and chills, dehumidifying blood-arthralgia, by ailment said due to cold or exposure, loosing the interspaces of skin and muscles. " 2. " not Lu ": " main phlegm is cold, angina in abdomen,Zhu Lengshi does not disappear, middle evil, pain in the chest and abdomen, contrary gas, sharp the five internal organs. " 3. " property of medicine opinion ": " main trusted subordinate's disease, long-pending cold,Under the heart, tie gas, Zhu is pained; Control choleraic myospasm, cold in the stomach gas, the stomachache of vomiting and diarrhoea can not win the person of bearing; Treat all over stupidNumbness, cold food does not disappear, and sharp large intestine is gathered around gas. " 4. supplement to the Herbal: " kills and dislikes worm poison, and tooth worm is hidden. " 5. " dayChina's son book on Chinese herbal medicine ": " invigorating the spleen is got round by bribery. Control stomachache, kidney qi, beriberi, oedema, lower postpartum remaining blood. " 6. king is goodAncient: " control ruffian and completely fill in chest, pharynx diaphragm is obstructed, the dry spleen of profit liver. It is stagnant that " 7. " detailed outline ": " opens strongly fragrantization. Control acid regurgitation,The cloudy sputum that falls is had a headache, insidious stomachache, hernia, bloody flux, mouthpiece's aphtha. " [usage and dosage] is for oral administration: decoctSoup, 0.5~2 money; Or enter ball, loose. External application: steaming is pressed, grinds into powder and dresses or decoct washing. [attention] the moonThe prosperous person of the fire of deficiency type avoids clothes. 1. Collective Notes to the Canon of Materia medica: " knotweed is real to be made for it. Dislike the red sage root, niter, chalk, fear is purpleQuartz. " 2. " book on Chinese herbal medicine covers bamboo fish trap ": " the intestines void person of letting out avoid especially. " 3. " detailed outline ": " is flat, get angry, and confused order,Send out sore. " 4. " Bencao Jingshu ": " vomiting acid regurgitation belongs to stomach fire person and should not use; Cough with dyspnea, non-chill outer evil andDue to cold phlegm Su Shui, person should not use; Stomachache belongs to the deficiency of blood has fiery person to use; Red white diarrhea, because summer-heat evil enters intestinesStomach, but not food and drink raw food, stagnate incrustation person and should not use; Herria, non-rapid sense cold-evil and onset one, twoInferior person should not use; Choleraic myospasm, due to weakness of the spleen and the stomach heat-stroke, but not cold-dampness raw food is in violating stomach person notShould use; The card of all deficiency of Yin and the vital organs of the human body have heat without cold people, and method institute is salty to be avoided.
Jasmine [source] Oleaceae Jasmine platymiscium jasmine Jasminumsambac (L.) Aiton,Be used as medicine with root and flower. Uproot, section is dried after autumn; Xia Qiu picks flowers, and dries. [nature and flavor] acrid, sweet, cool.Root is poisonous. [function cures mainly] flower, leaf: relieving superficies by cooling, dampness removing. For fever caused by exogenous pathogens, diarrhoea; Outside spendingWith controlling red eye, swell pain. Root: analgesia. For insomnia, traumatic injury. [usage and dosage] spent, leaf 1~2 money,Flower suitable amount used externally, decocts washing eye. Root 1~2 money, suitable amount used externally, mashes deposited affected part. [extracts] " whole nationChinese herbal medicine compilation ".
Rose rhodobryum herb [another name] Rhodobryum giganteum, fennel firewood grass, iron pin yunna spiraea, gigantism rhodobryum herb [source] mossWarm ground of Bryaceae rhodobryum spp plant great Ye moss Rhodobryumgiganteum (Schwaegr.) Par.,With all herbal medicine. Can adopt the whole year, using fresh herb or dry in the shade. [nature and flavor] are pungent, bitter, flat. [function cures mainly] supportsHeart and tranquilizing mind, clears liver and improve vision. For palpitation and severe palpitation, neurasthenia; Red eye, swell pain is controlled in external application. [usage and dosage]1~3 money; Suitable amount used externally, decocts water smoking and washes.
Wild chervil [source] Umbelliferae Anthriscus plant wild chervil Anthriscussylvestris (L.) Hoffm.,Be used as medicine with root, leaf. When 8~September aerial part flavescence, uproot, clean and boil, go crust to dry or dry;Leaf using fresh herb or dry levigation. [nature and flavor] sweet, pungent, micro-hardship, tepor. [function cures mainly] tonifying middle-Jiao and Qi,Removing blood stasis for promoting tissue regeneration. Root: for traumatic injury, pain in the back, cough due to deficiency of the lung, cough spitting of blood, splenasthenic abdominal distention, four limbsUnable, old man's frequent micturition, oedema; Leaf: wound [usage and dosage] root 4~5 money are controlled in external application; Leaf external application is suitableAmount, fresh leaf is mashed or cured leaf levigation applies affected part [extracts] " national Chinese herbal medicine compilation ".
The Preparation process product that astragalus root [source] this product is the Radix Astragali. [proterties] this product is circular or ovalSheet, diameter 0.8~3.5cm, thick 0.1~0.4cm. The shallow pale brown or sepia of exocuticle, slightly glossy,Visible vertical wrinkle or longitudinal furrow. Tangent plane skin zone is light yellow, and xylem yellow has radial texture and crack, hasCenter even have a dry and decayed shape, pitchy or be cavity. Tool honey fragrance, taste is sweet, slightly stickiness, that chews micro-ly hasBeany flavor. [process of preparing Chinese medicine] gets astragalus mongholicus tablet, processs method (annex IID) fry to tack-free according to honey. [nature and flavor] are sweet,Temperature. [return through] returns lung, the spleen channel. [function cures mainly] beneficial gas bowl spares. Weak for the deficiency of vital energy, anorexia and loose stool.[usage and dosage] 9~30g.
Radix Glycyrrhizae [source] this product is glycyrrhizic legume GlycyrrhizauralensisFisch., swollenFruit Radix Glycyrrhizae GlycyrrhizainflataBat. or glycyrrhiza glabra GlycyrrhizaglabraL.'s is dryDry. Spring, Qiu Erji excavate, and remove fibrous root, dry. [process of preparing Chinese medicine] removes impurity, cleans, run through,Cut sheet, dry. [nature and flavor] are sweet, flat. [return through] thoughts of returning home, lung, spleen, stomach warp. [function cures mainly]Invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription. For weakness of the spleen and the stomach, burnoutWeak, palpitation, coughing with a lot of sputum, gastral cavity abdomen, the anxious pain of four limbs contraction, carbuncle sore tumefacting virus, cushion toxicity,Strong. [usage and dosage] 1.5~9g. [attention] should not be with Beijing spurge root, lilac daphne, the root of gansui with using. [storageHide] put aeration-drying place, mothproof. [extracts] " Chinese pharmacopoeia ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine that is used for the treatment of senile insomnia, by select suitable medicinal material andIts proportioning, reaches the object of safe and effective healing senile insomnia.
In order to achieve the above object, the present invention is by the following technical solutions:
A Chinese medicine that is used for the treatment of senile insomnia, is characterized in that, it is former by following weight proportionMaterial medicinal material is prepared from: 6 parts of cortex albiziaes, 3 parts of evodia rutaecarpas, 6 parts of Jasmines, 8 parts of rose rhodobryum herbs, wild chervil12 parts, 15 parts of astragalus roots, 3 parts, Radix Glycyrrhizae.
Below in conjunction with clinical trial data declaration beneficial effect of the present invention:
1, physical data
Outpatient service insomniac 106 examples are collected between year April altogether in inventor in September, 2010~2013. Man's 50 examples,Female's 56 examples, age 65-84 year. Be divided at random treatment group 56 example and control group 50 examples. Two groups of sexes, yearThe comparing difference not statistically significants such as age, the course of disease, the front symptom for the treatment of, have comparativity.
Diagnostic criteria: 1, to be insomnia as primary symptom, the lighter's difficulty of falling asleep or sleep but easy to wake, be insomnia after waking up, severe oneLie awake all night; 2, often with palpitaition, dizziness, forgetful, dreaminess, the disease such as vexed; (3) often have eating and drinking without temperance,Abnormal emotion, overstrain, worry beyond measure, after being ill, the medical history such as body void.
2, test method
2.1 methods for the treatment of
The decoction that the oral the present invention of test group makes according to specific embodiment 1, every day 3 times. 4 weeks courses for the treatment of.
1 of the oral estazolam of control group, per os hora somni. 4 weeks courses for the treatment of.
3, criterion of therapeutical effect and treatment results
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms, sign disappear completely;
Effective: clinical cardinal symptom, sign disappear substantially;
Effective: clinical cardinal symptom, sign alleviate;
Invalid: not reach above-mentioned effective standard or deterioration person.
3.2 treatment results are in table 1
Table 1 liang group clinical efficacy result comparison
Group |
n |
Recovery from illness |
Effective |
Effectively |
Invalid |
Total effective rate (%) |
Bad reaction example |
Treatment group |
56 |
18 |
28 |
8 |
2 |
96.4% |
0 |
Control group |
50 |
0 |
21 |
19 |
10 |
80% |
3 |
Result is visible, and Chinese medicine of the present invention can the safe and effective treatment for senile insomnia.