CN104083439A - Berberis sargentiana Schneid-Scutellaria baicalensis anti-inflammatory drug and preparation method thereof - Google Patents
Berberis sargentiana Schneid-Scutellaria baicalensis anti-inflammatory drug and preparation method thereof Download PDFInfo
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- CN104083439A CN104083439A CN201410274753.1A CN201410274753A CN104083439A CN 104083439 A CN104083439 A CN 104083439A CN 201410274753 A CN201410274753 A CN 201410274753A CN 104083439 A CN104083439 A CN 104083439A
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention discloses a Berberis sargentiana Schneid-Scutellaria baicalensis anti-inflammatory tablet and a preparation method thereof. The anti-inflammatory tablet is prepared from the two traditional Chinese medicines consisting of Berberis sargentiana Schneid and Scutellaria baicalensis, is orally taken and can effectively alleviate symptoms like sore throat, diarrhoea and dysentery. The tablet has no toxic and side effects and is applicable to all the people; in a treatment group consisting of 50 persons, 47 persons are completely cured, the symptoms of 2 persons are mitigated, the treatment effect on 1 person is not good, so the total efficiency rate of the tablet is more than 98%.
Description
Technical field
Two yellow antibiotic medicine of the present invention relates to and preparation method thereof.
Background technology
People in daily life and work because autoimmune system is low or had sore throat or gastrointestinal upset by the unavoidable occasional of natural environment influence, especially when arrive summer because diet is irregular or the unhygienic diseases such as diarrhoea, dysentery that often there will be.Especially be in recent years subject to that natural environment influence is had sore throat, the sickness rate of gastrointestinal upset is in rising trend.The method for the treatment of is varied, and medicine has Chinese medicine and western medicine etc.
Summary of the invention
In view of above-mentioned the deficiencies in the prior art, the object of the present invention is to provide two yellow Pianomides and preparation method thereof, to improve therapeutic effect, promote patient's rehabilitation.
Technical scheme of the present invention is as follows:
Two yellow Pianomides, wherein, it is the tablet of being made by the raw material of following weight proportioning:
Radix Berberidis 400-500 part, Radix Scutellariae 100-200 part.
Described two yellow Pianomide, wherein, it is the tablet of being made by the raw material of following weight:
Radix Berberidis 450g, Radix Scutellariae 150g.
Described two yellow Pianomide, wherein, it is the tablet of being made by the raw material of following weight proportioning:
450 parts of Radix Berberidis, 150 parts of Radix Scutellariaes.
The preparation method of described two yellow Pianomides, it comprises the following steps:
A, according to Radix Berberidis 400-500 part, Radix Scutellariae 100-200 part, obtain weight proportion and be ready to raw material, get Radix Scutellariae 80-100 part and be ground into fine powder; All the other Radix Scutellariaes decoct with water three times, and 3 hours for the first time, 1 hour for the second time, 0.5 hour for the third time, collecting decoction, filtered; .
For B, Radix Berberidis, 45% alcohol heating reflux extracts secondary, and merge extractive liquid, filters, and filtrate recycling ethanol merges with above-mentioned filtrate, and being concentrated into relative density is 1.35～1.40(50 ℃) clear paste; .
C, clear paste and above-mentioned Radix Scutellariae powder are mixed, dry, pulverize into fine powder, granulation, dry, be pressed into 350, obtain two yellow Pianomides.。
The pharmacological action of each Chinese medicine:
Radix Berberidis: cold in nature, micro-hardship, nontoxic.Function with cure mainly: heat clearing away, dampness removing, dissipating blood stasis.Control bloody dysentery, jaundice, pharyngalgia, conjunctival congestion, traumatic injury.
Radix Scutellariae: hardship, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Function with cure mainly: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive, blood pressure lowering.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Two yellow Pianomides provided by the invention and preparation method thereof, are made by Radix Berberidis and Radix Scutellariae two taste Chinese medicines, oral, one time 3,3 times on the one, for treatment, have sore throat and there is obvious effect with the inflammation of gastrointestinal upset.
Discrimination method:
(1) get this product, put micro-Microscopic observation: fiber is faint yellow, fusiformis, wall thickness, hole ditch is thin.
(2) get 1 of this product, porphyrize, adds methanol 5ml, puts in water-bath reflux 10 minutes, filters, and filtrate is as need testing solution.Separately get berberine hydrochloride trick product are made to every 1ml containing the solution of 0.5mg, in contrast product solution with methanol.According to thin layer chromatography test, draw each 1～2 μ l of above-mentioned two kinds of solution, put respectively in same and take on the silica GF254 lamellae that sodium carboxymethyl cellulose is binding agent, under uviol lamp (365nm), inspect.In test sample chromatograph with the corresponding position of reference substance chromatograph on, the fluorescence speckle of aobvious same color.
The specific embodiment
The invention provides two yellow Pianomides and preparation method thereof, for making object of the present invention, technical scheme and effect clearer, clear and definite, below the present invention is described in more detail.Should be appreciated that specific embodiment described herein, only in order to explain the present invention, is not intended to limit the present invention.
Two yellow Pianomide provided by the invention, it is the tablet of being made by the raw material of following weight proportioning:
Radix Berberidis 400-500 part, Radix Scutellariae 100-200 part.
Further, described two yellow Pianomide is the tablet of being made by the raw material of following weight proportioning:
450 parts of Radix Berberidis, 150 parts of Radix Scutellariaes.
In most preferred embodiment of the present invention, described two yellow Pianomides are tablets of being made by the raw material of following weight:
Radix Berberidis 450g, Radix Scutellariae 150g.
The present invention also provides the preparation method of two yellow Pianomides, and it comprises the following steps:
Step 101: obtain weight proportion and be ready to raw material according to Radix Berberidis 400-500 part, Radix Scutellariae 100-200 part, get Radix Scutellariae 80-100 part and be ground into fine powder; All the other Radix Scutellariaes decoct with water three times, and 3 hours for the first time, 1 hour for the second time, 0.5 hour for the third time, collecting decoction, filtered;
Step 102: 45% alcohol heating reflux extracts secondary for Radix Berberidis, merge extractive liquid,, filters, filtrate recycling ethanol merges with above-mentioned filtrate, being concentrated into relative density is 1.35～1.40(50 ℃) clear paste;
Step 103: clear paste and above-mentioned Radix Scutellariae powder are mixed, dry, pulverize into fine powder, granulation, dry, be pressed into 350, obtain two yellow Pianomides.
By above-mentioned technique, Radix Berberidis and Radix Scutellariae are made to the two yellow Pianomide obtaining, oral, one time 3,3 times on the one.After the course for the treatment of, substantially all patients all can rehabilitation.In above-mentioned technique, each component can be adjusted as required flexibly, such as adopting the combination of Radix Berberidis 450g, Radix Scutellariae 150g.
In order to show the therapeutic effect of medicine of the present invention, by treatment group and contrast groups, compare the Diseases such as treatment group and contrast groups are and have sore throat, diarrhoea, dysentery.Treatment group number is 50 people, male patient 30 people in age 20-50 year wherein, female patient 20 people in age 25-60 year.Contrast groups number is 50 people, and wherein age 20-40 year obtains male patient 25 people, female patient 25 people of age 35-50.Treatment group according to one time three, every day the usage of three times, symptom obviously alleviates after three days, cured person 48 people.Illustrating that two yellow Pianomide of the present invention can obviously be alleviated has sore throat and stomach malaise symptom.
That in 50 people of above-mentioned treatment group, cure completely is 47 people, and 2 people's symptoms alleviate, and 1 people's effect is poor, and overall efficiency is more than 98%.
Should be understood that; application of the present invention is not limited to above-mentioned giving an example; for those of ordinary skills; can be improved according to the above description or be converted; the protection domain that all these improvement and conversion all should belong to claims of the present invention should be understood that; application of the present invention is not limited to above-mentioned giving an example; for those of ordinary skills; can be improved according to the above description or convert, all these improvement and conversion all should belong to the protection domain of claims of the present invention.
Claims (4)
1. pair yellow Pianomide, is characterized in that, it is the tablet of being made by the raw material of following weight proportioning:
Radix Berberidis 400-500 part, Radix Scutellariae 100-200 part.
2. two yellow Pianomide according to claim 1, is characterized in that, it is the tablet of being made by the raw material of following weight:
Radix Berberidis 450g, Radix Scutellariae 150g.
3. two yellow Pianomide according to claim 1, is characterized in that, it is the tablet of being made by the raw material of following weight proportioning:
450 parts of Radix Berberidis, 150 parts of Radix Scutellariaes.
4. a preparation method for two yellow Pianomides as claimed in claim 1, it comprises the following steps:
A, according to Radix Berberidis 400-500 part, Radix Scutellariae 100-200 part, obtain weight proportion and be ready to raw material, get Radix Scutellariae 80-100 part and be ground into fine powder; All the other Radix Scutellariaes decoct with water three times, and 3 hours for the first time, 1 hour for the second time, 0.5 hour for the third time, collecting decoction, filtered;
For B, Radix Berberidis, 45% alcohol heating reflux extracts secondary, and merge extractive liquid, filters, and filtrate recycling ethanol merges with above-mentioned filtrate, and being concentrated into relative density is 1.35～1.40(50 ℃) clear paste;
C, clear paste and above-mentioned Radix Scutellariae powder are mixed, dry, pulverize into fine powder, granulation, dry, be pressed into 350, obtain two yellow Pianomides.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410274753.1A CN104083439A (en) | 2014-06-19 | 2014-06-19 | Berberis sargentiana Schneid-Scutellaria baicalensis anti-inflammatory drug and preparation method thereof |
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| CN201410274753.1A CN104083439A (en) | 2014-06-19 | 2014-06-19 | Berberis sargentiana Schneid-Scutellaria baicalensis anti-inflammatory drug and preparation method thereof |
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| CN104083439A true CN104083439A (en) | 2014-10-08 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104435111A (en) * | 2014-11-27 | 2015-03-25 | 江西百神药业股份有限公司 | Preparation method for antiphlogistic capsule composition prepared from berberis anhweiensis ahrendt and scutellaria baicalensis |
| CN105816523A (en) * | 2016-03-17 | 2016-08-03 | 韩志强 | Shuanghuang inflammation eliminating tablet and preparation method thereof |
| CN107595995A (en) * | 2017-10-23 | 2018-01-19 | 贵州拜特制药有限公司 | Pharmaceutical composition and application, kit and package for gynaecological imflammation |
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| CN1660374A (en) * | 2005-01-31 | 2005-08-31 | 北京正大绿洲医药科技有限公司 | 'Shuanghuang' antiphlogistic drop pill in use relieving inflammation and preparation method |
| CN1709334A (en) * | 2005-06-14 | 2005-12-21 | 胡锦国 | Shuanghuan anti-inflammation dispersion tablet of radix berberidis and radix scutellariae and its preparing method |
| CN101766687A (en) * | 2010-02-26 | 2010-07-07 | 江西百神药业集团有限公司 | Inflammation diminishing capsules prepared from baical skullcap root and golden thread and preparation method thereof |
| KR20140065061A (en) * | 2012-11-21 | 2014-05-29 | 김영일 | Herbal medicines using natural antibacterial , anti-inflammatory solution |
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2014
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| CN1660374A (en) * | 2005-01-31 | 2005-08-31 | 北京正大绿洲医药科技有限公司 | 'Shuanghuang' antiphlogistic drop pill in use relieving inflammation and preparation method |
| CN1709334A (en) * | 2005-06-14 | 2005-12-21 | 胡锦国 | Shuanghuan anti-inflammation dispersion tablet of radix berberidis and radix scutellariae and its preparing method |
| CN101766687A (en) * | 2010-02-26 | 2010-07-07 | 江西百神药业集团有限公司 | Inflammation diminishing capsules prepared from baical skullcap root and golden thread and preparation method thereof |
| KR20140065061A (en) * | 2012-11-21 | 2014-05-29 | 김영일 | Herbal medicines using natural antibacterial , anti-inflammatory solution |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104435111A (en) * | 2014-11-27 | 2015-03-25 | 江西百神药业股份有限公司 | Preparation method for antiphlogistic capsule composition prepared from berberis anhweiensis ahrendt and scutellaria baicalensis |
| CN104435111B (en) * | 2014-11-27 | 2018-09-28 | 江西百神药业股份有限公司 | A kind of preparation method of double yellow antiphlogistic capsule compositions |
| CN105816523A (en) * | 2016-03-17 | 2016-08-03 | 韩志强 | Shuanghuang inflammation eliminating tablet and preparation method thereof |
| CN107595995A (en) * | 2017-10-23 | 2018-01-19 | 贵州拜特制药有限公司 | Pharmaceutical composition and application, kit and package for gynaecological imflammation |
| CN107595995B (en) * | 2017-10-23 | 2020-07-28 | 贵州拜特制药有限公司 | Pharmaceutical composition for gynecological inflammation and application, kit and package |
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