CN1660374A - 'Shuanghuang' antiphlogistic drop pill in use relieving inflammation and preparation method - Google Patents
'Shuanghuang' antiphlogistic drop pill in use relieving inflammation and preparation method Download PDFInfo
- Publication number
- CN1660374A CN1660374A CN200510004956XA CN200510004956A CN1660374A CN 1660374 A CN1660374 A CN 1660374A CN 200510004956X A CN200510004956X A CN 200510004956XA CN 200510004956 A CN200510004956 A CN 200510004956A CN 1660374 A CN1660374 A CN 1660374A
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- CN
- China
- Prior art keywords
- polyethylene glycol
- drug extract
- substrate
- drop pill
- mixed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Medicinal Preparation (AREA)
Abstract
Description
The substrate title | Effective ingredient (%) | Rounding rate (%) | Dissolve scattered time limit (minute) | The ball method of double differences different (%) | Hardness |
Polyethylene Glycol 2000 | ????50.0 | ????60 | ????<30 | ????>10 | + |
Polyethylene Glycol 4000 | ????50.0 | ????76 | ????<30 | ????>10 | + |
Polyethylene Glycol 6000 | ????50.0 | ????76 | ????<30 | ????>10 | ++ |
Polyethylene Glycol 8000 | ????50.0 | ????75 | ????<30 | ????>10 | ++ |
Polyethylene Glycol 10000 | ????50.0 | ????78 | ????<30 | ????>10 | ++ |
Polyethylene Glycol 20000 | ????50.0 | ????80 | ????<30 | ????>10 | ++ |
Polyoxyethylene stearate 40 esters | ????50.0 | ????75 | ????<30 | ????>10 | ++ |
Betacyclodextrin | ????50.0 | ????68 | ????<30 | ????>10 | + |
Poloxamer | ????50.0 | ????75 | ????<30 | ????>10 | ++ |
Carboxymethyl starch sodium | ????50.0 | ????73 | ????<30 | ????>10 | + |
Sodium lauryl sulphate | ????50.0 | ????66 | ????>30 | ????>10 | ++ |
Stearic acid | ????50.0 | ????54 | ????>30 | ????>10 | ++ |
Sodium stearate | ????50.0 | ????54 | ????>30 | ????>10 | ++ |
Glycerin gelatine | ????50.0 | ????53 | ????>30 | ????>10 | + |
Lac | ????50.0 | ????52 | ????>30 | ????>10 | + |
The substrate title | Effective ingredient (%) | Rounding rate (%) | Dissolve scattered time limit (minute) | The ball method of double differences different (%) | Hardness |
Polyethylene Glycol 2000 | ????25.0 | ????79 | ????<30 | ????>10 | ++ |
Polyethylene Glycol 4000 | ????25.0 | ????86 | ????<30 | ????<10 | +++ |
Polyethylene Glycol 6000 | ????25.0 | ????91 | ????<30 | ????<10 | +++ |
Polyethylene Glycol 8000 | ????25.0 | ????91 | ????<30 | ????<10 | +++ |
Polyethylene Glycol 10000 | ????25.0 | ????92 | ????<30 | ????<10 | +++ |
Polyethylene Glycol 20000 | ????25.0 | ????92 | ????<30 | ????<10 | +++ |
Polyoxyethylene stearate 40 esters | ????25.0 | ????93 | ????<30 | ????<10 | ++ |
Betacyclodextrin | ????25.0 | ????83 | ????<30 | ????>10 | ++ |
Poloxamer | ????25.0 | ????91 | ????<30 | ????<10 | +++ |
Carboxymethyl starch sodium | ????25.0 | ????86 | ????<30 | ????<10 | +++ |
Sodium lauryl sulphate | ????25.0 | ????77 | ????<30 | ????>10 | ++ |
Stearic acid | ????25.0 | ????73 | ????>30 | ????>10 | +++ |
Sodium stearate | ????25.0 | ????71 | ????>30 | ????>10 | +++ |
Glycerin gelatine | ????25.0 | ????70 | ????>30 | ????>10 | +++ |
Lac | ????25.0 | ????70 | ????>30 | ????>10 | +++ |
The substrate title | Effective ingredient (%) | Rounding rate (%) | Dissolve scattered time limit (minute) | The ball method of double differences different (%) | Hardness |
Polyethylene Glycol 2000 | ????10.0 | ????80 | ????<30 | ????>10 | ++ |
Polyethylene Glycol 4000 | ????10.0 | ????86 | ????<30 | ????<10 | +++ |
Polyethylene Glycol 6000 | ????10.0 | ????90 | ????<30 | ????<10 | +++ |
Polyethylene Glycol 8000 | ????10.0 | ????90 | ????<30 | ????<10 | +++ |
Polyethylene Glycol 10000 | ????10.0 | ????92 | ????<30 | ????<10 | +++ |
Polyethylene Glycol 20000 | ????10.0 | ????93 | ????<30 | ????<10 | +++ |
Polyoxyethylene stearate 40 esters | ????10.0 | ????92 | ????<30 | ????<10 | ++ |
Betacyclodextrin | ????10.0 | ????81 | ????<30 | ????>10 | ++ |
Poloxamer | ????10.0 | ????90 | ????<30 | ????<10 | +++ |
Carboxymethyl starch sodium | ????10.0 | ????87 | ????<30 | ????<10 | +++ |
Sodium lauryl sulphate | ????10.0 | ????79 | ????<30 | ????>10 | +++ |
Stearic acid | ????10.0 | ????76 | ????>30 | ????>10 | +++ |
Sodium stearate | ????10.0 | ????75 | ????>30 | ????>10 | +++ |
Glycerin gelatine | ????10.0 | ????72 | ????>30 | ????>10 | +++ |
Lac | ????10.0 | ????72 | ????>30 | ????>10 | +++ |
The substrate title | Effective ingredient (%) | Rounding rate (%) | Dissolve scattered time limit (minute) | The ball method of double differences different (%) | Hardness |
Polyoxyethylene stearate 40 esters: Polyethylene Glycol=1: 1 | ????50 | ????84 | ????<30 | ????>10 | ++ |
Poloxamer: Polyethylene Glycol=1: 1 | ????50 | ????82 | ????<30 | ????>10 | ++ |
Carboxymethyl starch sodium: Polyethylene Glycol=1: 1 | ????50 | ????79 | ????<30 | ????>10 | ++ |
Betacyclodextrin: Polyethylene Glycol=1: 1 | ????50 | ????72 | ????<30 | ????>10 | + |
The substrate title | Effective ingredient (%) | Rounding rate (%) | Dissolve scattered time limit (minute) | The ball method of double differences different (%) | Hardness |
Polyoxyethylene stearate 40 esters: Polyethylene Glycol=1: 1 | ????25 | ????88 | ????<30 | ????<10 | +++ |
Poloxamer: Polyethylene Glycol=1: 1 | ????25 | ????89 | ????<30 | ????<10 | +++ |
Carboxymethyl starch sodium: Polyethylene Glycol=1: 1 | ????25 | ????86 | ????<30 | ????<10 | +++ |
Betacyclodextrin: Polyethylene Glycol=1: 1 | ????25 | ????82 | ????<30 | ????>10 | ++ |
The substrate title | Effective ingredient (%) | Rounding rate (%) | Dissolve scattered time limit (minute) | The ball method of double differences different (%) | Hardness |
Polyoxyethylene stearate 40 esters: Polyethylene Glycol=1: 1 | ????10 | ????88 | ????<30 | ????<10 | +++ |
Poloxamer: Polyethylene Glycol=1: 1 | ????10 | ????86 | ????<30 | ????<10 | +++ |
Carboxymethyl starch sodium: Polyethylene Glycol=1: 1 | ????10 | ????83 | ????<30 | ????>10 | +++ |
Betacyclodextrin: Polyethylene Glycol=1: 1 | ????10 | ????80 | ????<30 | ????>10 | +++ |
The substrate title | Effective ingredient (%) | Rounding rate (%) | Dissolve scattered time limit (minute) | The ball method of double differences different (%) | Hardness |
Polyoxyethylene stearate 40 esters: Polyethylene Glycol=1: 5 | ????50 | ????91 | ????<30 | ????<10 | +++ |
Poloxamer: Polyethylene Glycol=1: 5 | ????50 | ????90 | ????<30 | ????<10 | +++ |
Carboxymethyl starch sodium: Polyethylene Glycol=1: 5 | ????50 | ????90 | ????<30 | ????<10 | +++ |
Betacyclodextrin: Polyethylene Glycol=1: 5 | ????50 | ????86 | ????<30 | ????<10 | ++ |
The substrate title | Effective ingredient (%) | Rounding rate (%) | Dissolve scattered time limit (minute) | The ball method of double differences different (%) | Hardness |
Polyoxyethylene stearate 40 esters: Polyethylene Glycol=1: 5 | ????25 | ????93 | ????<30 | ????<10 | +++ |
Poloxamer: Polyethylene Glycol=1: 5 | ????25 | ????93 | ????<30 | ????<10 | +++ |
Carboxymethyl starch sodium: Polyethylene Glycol=1: 5 | ????25 | ????91 | ????<30 | ????<10 | +++ |
Betacyclodextrin: Polyethylene Glycol=1: 5 | ????25 | ????88 | ????<30 | ????<10 | +++ |
The substrate title | Effective ingredient (%) | Rounding rate (%) | Dissolve scattered time limit (minute) | The ball method of double differences different (%) | Hardness |
Polyoxyethylene stearate 40 esters: Polyethylene Glycol=1: 5 | ????10 | ????93 | ????<30 | ????<10 | +++ |
Poloxamer: Polyethylene Glycol=1: 5 | ????10 | ????92 | ????<30 | ????<10 | +++ |
Carboxymethyl starch sodium: Polyethylene Glycol=1: 5 | ????10 | ????92 | ????<30 | ????<10 | +++ |
Betacyclodextrin: Polyethylene Glycol=1: 5 | ????10 | ????89 | ????<30 | ????<10 | +++ |
The substrate title | Effective ingredient (%) | Rounding rate (%) | Dissolve scattered time limit (minute) | The ball method of double differences different (%) | Hardness |
Polyoxyethylene stearate 40 esters: Polyethylene Glycol=1: 10 | ????50 | ????92 | ????<30 | ????<10 | +++ |
Poloxamer: Polyethylene Glycol=1: 10 | ????50 | ????91 | ????<30 | ????<10 | +++ |
Carboxymethyl starch sodium: Polyethylene Glycol=1: 10 | ????50 | ????87 | ????<30 | ????<10 | +++ |
Betacyclodextrin: Polyethylene Glycol=1: 10 | ????50 | ????84 | ????<30 | ????>10 | +++ |
The substrate title | Effective ingredient (%) | Rounding rate (%) | Dissolve scattered time limit (minute) | The ball method of double differences different (%) | Hardness |
Polyoxyethylene stearate 40 esters: Polyethylene Glycol=1: 10 | ????25 | ????92 | ????<30 | ????<10 | +++ |
Poloxamer: Polyethylene Glycol=1: 10 | ????25 | ????92 | ????<30 | ????<10 | +++ |
Carboxymethyl starch sodium: Polyethylene Glycol=1: 10 | ????25 | ????89 | ????<30 | ????<10 | +++ |
Betacyclodextrin: Polyethylene Glycol=1: 10 | ????25 | ????87 | ????<30 | ????<10 | +++ |
The substrate title | Effective ingredient (%) | Rounding rate (%) | Dissolve scattered time limit (minute) | The ball method of double differences different (%) | Hardness |
Polyoxyethylene stearate 40 esters: Polyethylene Glycol=1: 10 | ????10 | ????91 | ????<30 | ????<10 | +++ |
Poloxamer: Polyethylene Glycol=1: 10 | ????10 | ????92 | ????<30 | ????<10 | +++ |
Carboxymethyl starch sodium: Polyethylene Glycol=1: 10 | ????10 | ????91 | ????<30 | ????<10 | +++ |
Betacyclodextrin: Polyethylene Glycol=1: 10 | ????10 | ????91 | ????<30 | ????<10 | +++ |
Claims (5)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB200510004956XA CN100341487C (en) | 2005-01-31 | 2005-01-31 | 'Shuanghuang' antiphlogistic drop pill in use relieving inflammation and preparation method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB200510004956XA CN100341487C (en) | 2005-01-31 | 2005-01-31 | 'Shuanghuang' antiphlogistic drop pill in use relieving inflammation and preparation method |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1660374A true CN1660374A (en) | 2005-08-31 |
CN100341487C CN100341487C (en) | 2007-10-10 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB200510004956XA Expired - Fee Related CN100341487C (en) | 2005-01-31 | 2005-01-31 | 'Shuanghuang' antiphlogistic drop pill in use relieving inflammation and preparation method |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN100341487C (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110111070A1 (en) * | 2007-10-25 | 2011-05-12 | Yung-Chi Cheng | Use of phy906 as treatment for inflammatory bowel disease and/or irritable bowel syndrome |
CN104083439A (en) * | 2014-06-19 | 2014-10-08 | 通化万通药业股份有限公司 | Berberis sargentiana Schneid-Scutellaria baicalensis anti-inflammatory drug and preparation method thereof |
CN109999117A (en) * | 2019-05-24 | 2019-07-12 | 湖南泰谷生物兽药有限公司 | Prevent and treat enteritis, bacillary dysentery, dysentery, intractable diarrhea Chinese medicine composition |
-
2005
- 2005-01-31 CN CNB200510004956XA patent/CN100341487C/en not_active Expired - Fee Related
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110111070A1 (en) * | 2007-10-25 | 2011-05-12 | Yung-Chi Cheng | Use of phy906 as treatment for inflammatory bowel disease and/or irritable bowel syndrome |
CN104083439A (en) * | 2014-06-19 | 2014-10-08 | 通化万通药业股份有限公司 | Berberis sargentiana Schneid-Scutellaria baicalensis anti-inflammatory drug and preparation method thereof |
CN109999117A (en) * | 2019-05-24 | 2019-07-12 | 湖南泰谷生物兽药有限公司 | Prevent and treat enteritis, bacillary dysentery, dysentery, intractable diarrhea Chinese medicine composition |
Also Published As
Publication number | Publication date |
---|---|
CN100341487C (en) | 2007-10-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: QINGDAO ZHENGDA HAIER PHARMACEUTICAL CO., LTD. AD Free format text: FORMER OWNER: ZHENGDA-LUZHOU MEDICINE SCIENCE-TECHNOLOGY CO., LTD., BEIJING ADDRESS Effective date: 20081121 |
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C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20081121 Address after: No. 1, Haier Road, Qingdao Patentee after: Qingdao Zhengda Haier Pharmaceutical Co., Ltd. Address before: Beijing economic and Technological Development Zone Hongda North Road, 12 innovation building, block B, two, 201 Patentee before: Beijing Zhengda Oasis Medicine Technology Co., Ltd. |
|
EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Qingdao Zhengda Haier Pharmaceutical Co., Ltd. Assignor: Beijing Zhengda Oasis Medicine Technology Co., Ltd. Contract fulfillment period: 2008.10.28 to 2013.10.28 contract change Contract record no.: 2008990000981 Denomination of invention: 'Shuanghuang' antiphlogistic drop pill in use relieving inflammation and preparation method Granted publication date: 20071010 License type: Exclusive license Record date: 20081029 |
|
ASS | Succession or assignment of patent right |
Owner name: QINGDAO ZHENGDA HAIER PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: ZHENGDA-LUZHOU MEDICINE SCIENCE-TECHNOLOGY CO., LTD., BEIJING Effective date: 20081121 |
|
LIC | Patent licence contract for exploitation submitted for record |
Free format text: EXCLUSIVE LICENSE; TIME LIMIT OF IMPLEMENTING CONTACT: 2008.10.28 TO 2013.10.28; CHANGE OF CONTRACT Name of requester: QINGDAO ZHENGDA HAIER PHARMACEUTICAL CO., LTD. Effective date: 20081029 |
|
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20071010 Termination date: 20170131 |
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CF01 | Termination of patent right due to non-payment of annual fee |