CN104066720A - 作为类香草素受体配体的具有被含so2-基团取代的苯基基团的被取代的基于吡唑基的羧酰胺和脲衍生物 - Google Patents

作为类香草素受体配体的具有被含so2-基团取代的苯基基团的被取代的基于吡唑基的羧酰胺和脲衍生物 Download PDF

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Publication number
CN104066720A
CN104066720A CN201280055221.8A CN201280055221A CN104066720A CN 104066720 A CN104066720 A CN 104066720A CN 201280055221 A CN201280055221 A CN 201280055221A CN 104066720 A CN104066720 A CN 104066720A
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phenyl
methyl
fluoro
methylsulfonyl
pyrazole
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Pending
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CN201280055221.8A
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Chinese (zh)
Inventor
R.弗兰克-福尔蒂恩
T.克里斯托弗
N.达曼
B.莱施
G.巴伦贝格
D.J.绍恩德斯
H.施托克豪森
金勇洙
金明燮
李智雨
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Gruenenthal GmbH
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Gruenenthal GmbH
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    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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CN201280055221.8A 2011-11-09 2012-11-08 作为类香草素受体配体的具有被含so2-基团取代的苯基基团的被取代的基于吡唑基的羧酰胺和脲衍生物 Pending CN104066720A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11008927.3 2011-11-09
EP11008927 2011-11-09
PCT/EP2012/072143 WO2013068464A1 (en) 2011-11-09 2012-11-08 Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an so2-containing group as vanilloid receptor ligands

Publications (1)

Publication Number Publication Date
CN104066720A true CN104066720A (zh) 2014-09-24

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CN201280055221.8A Pending CN104066720A (zh) 2011-11-09 2012-11-08 作为类香草素受体配体的具有被含so2-基团取代的苯基基团的被取代的基于吡唑基的羧酰胺和脲衍生物

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EP (1) EP2776401A1 (es)
JP (1) JP2014532744A (es)
KR (1) KR20140091041A (es)
CN (1) CN104066720A (es)
AR (1) AR088799A1 (es)
AU (1) AU2012334068A1 (es)
BR (1) BR112014011108A2 (es)
CA (1) CA2854424A1 (es)
HK (1) HK1202117A1 (es)
IN (1) IN2014KN00865A (es)
MX (1) MX2014005233A (es)
TW (1) TW201326135A (es)
WO (1) WO2013068464A1 (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107108593A (zh) * 2014-11-24 2017-08-29 美迪福伦Dbt有限公司 作为类香草素受体配体ii的基于取代的恶唑和噻唑的羧酰胺和脲衍生物
CN114920697A (zh) * 2022-05-16 2022-08-19 河南应用技术职业学院 杂环基取代的茚满丙酰胺类化合物及其应用

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2016011468A (es) 2014-03-07 2017-01-23 Biocryst Pharm Inc Inhibidores de calicreína plasmática humana.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010127856A1 (en) * 2009-05-07 2010-11-11 Grünenthal GmbH Substituted phenyllureas and phenylamides as vanilloid receptor ligands

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI1011192A2 (pt) 2009-05-07 2016-03-15 Gruenenthal Gmbh derivados de carboxamida e ureia aromáticas substituídas como ligantes de receptor de vaniloide, composição farmacêutica, uso e processo para preparação dos referidos derivados

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010127856A1 (en) * 2009-05-07 2010-11-11 Grünenthal GmbH Substituted phenyllureas and phenylamides as vanilloid receptor ligands

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107108593A (zh) * 2014-11-24 2017-08-29 美迪福伦Dbt有限公司 作为类香草素受体配体ii的基于取代的恶唑和噻唑的羧酰胺和脲衍生物
CN107108593B (zh) * 2014-11-24 2020-03-24 美迪福伦Dbt有限公司 作为类香草素受体配体ii的基于取代的恶唑和噻唑的羧酰胺和脲衍生物
CN114920697A (zh) * 2022-05-16 2022-08-19 河南应用技术职业学院 杂环基取代的茚满丙酰胺类化合物及其应用

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KR20140091041A (ko) 2014-07-18
BR112014011108A2 (pt) 2017-05-16
AU2012334068A1 (en) 2014-05-22
WO2013068464A1 (en) 2013-05-16
EP2776401A1 (en) 2014-09-17
MX2014005233A (es) 2014-08-22
HK1202117A1 (en) 2015-09-18
TW201326135A (zh) 2013-07-01
IN2014KN00865A (es) 2015-10-02
CA2854424A1 (en) 2013-05-16
AR088799A1 (es) 2014-07-10
JP2014532744A (ja) 2014-12-08

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Application publication date: 20140924