CN104055871A - Traditional Chinese medicinal composition for improving sleeping quality and application of traditional Chinese medicinal composition - Google Patents
Traditional Chinese medicinal composition for improving sleeping quality and application of traditional Chinese medicinal composition Download PDFInfo
- Publication number
- CN104055871A CN104055871A CN201410327414.5A CN201410327414A CN104055871A CN 104055871 A CN104055871 A CN 104055871A CN 201410327414 A CN201410327414 A CN 201410327414A CN 104055871 A CN104055871 A CN 104055871A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- traditional chinese
- medicine composition
- chinese medicinal
- sleep
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention discloses a traditional Chinese medicinal composition for improving sleeping quality and application of the traditional Chinese medicinal composition, and belongs to the field of traditional Chinese medicines and healthy foods. The traditional Chinese medicinal composition consists of spina date seed, lucid ganoderma, semen boitae and manyprickle acanthopanax root, and can be prepared into capsules, pills, powder, granules, tablets, oral solutions and other common oral preparations. Functional experiments prove that the traditional Chinese medicinal composition has the effect of improving sleeping, and can be produced into medicines or healthy foods with effect of improving sleeping.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and application thereof that improves sleep quality, belong to the field of Chinese medicines, also belong to field of health care food.
Background technology
Sleep disorder doctor trained in Western medicine refers to region of anatomy generation pathological changes or the physiological function disorder of sleep, causes the symptoms such as parahypnosis and hypersomnia.Motherland's medical science thinks that insomnia is for imbalance of YIN and YANG, qi-blood disharmony, and the latent the moon of sun causes.Sleep disorder is commonly encountered diseases, and hazardness is large, treatment difficulty.Be often referred to a kind of subjective experience that the length of one's sleep or quality is not met and affected social function on daytime, main manifestations is the deficiency of the length of one's sleep, the degree of depth, and can not allaying tiredness, regains one's strength and energy, the lighter's difficulty falling asleep, or sleep and unfoolish, sometimes sleeping and sometimes waking, or can not sleep again after waking up, heavy be insomnia all night, with spiritlessness and weakness, dizziness headache, palpitation and amnesia etc.At present, the incidence rate of sleep disorder is very high, and especially in youngster, number of the infected significantly increases.Sleep, as the necessary process of life, is the important step of body recovery, integration and consolidating memory, is healthy indispensable ingredient.
Semen Ziziphi Spinosae is Rhamnaceae jujube Ziziphi Spinosae
ziziphus jujuba Mill.Var.spinosa (Bunge) Hu ex H.F.Choudry seed.Another name Semen Ziziphi Spinosae, jujube nucleus.< < Sheng Nong's herbal classic > > classifies as top grade.< < Compendium of Materia Medica > > lists woody part class in.Modern < < Chinese materia medica > > lists medicine for nourishing the heart and tranquilizing the mind class in.Semen Ziziphi Spinosae sweet in the mouth, property is flat, has mind tranquilizing and the heart calming, arresting sweating, nourishing the liver function.For restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, the diseases such as dizziness and blurred vision.Modern medicine study also shows, Semen Ziziphi Spinosae has sedative-hypnotic effect.Jujuboside is the main effective ingredient of Semen Ziziphi Spinosae, wherein mainly contains jujuboside A, B.Jujuboside is one of main component of Semen Ziziphi Spinosae sedative-hypnotic effect, and the improvement of sleep is had to good effect.
Ganoderma
[Ganoderma lucidum (Leyss.ex Fr.) Kerst.]belong to Basidiomycotina, Hymenomycetes, Aphyllophorales, Polyporaceae, Ganoderma fungus, is commonly called as Ganoderma lucidum seu Japonicum, is exactly the famous and precious medicinal fungi of China since ancient times, the effect with benefiting vital QI for tranquillizing, strengthening the body resistance, is regarded as precious Chinese crude drug, is the treasure in pools of traditional Chinese medicine.In China medical science works < < Sheng Nong's herbal classic > > (Eastern Han Dynasty the earliest, 25-220), be listed in top grade, the < < of Ming Dynasty Compendium of Materia Medica > > (Li Shizhen (1518-1593 A.D.), 1590) has also spoken highly of its medical value.Modern pharmacology proves: Ganoderma contains several physiological active substances, and ganoderan is main effective ingredient, has the effects such as radioprotective, antitumor, adjusting blood glucose, blood fat reducing, hepatoprotective.Chinese medicine thinks that Ganoderma can " replenishing QI and blood, tranquilizing mind ", cures mainly asthenia, cardiopalmus, the diseases such as insomnia.
Semen Platycladi has another name called Bai Ren, cedar seed, is the fruit of Cupressaceae plant Cacumen Platycladi, and head is loaded in < < Sheng Nong's herbal classic > >.Its sweet in the mouth is flat, enters the heart, liver, kidney, large intestine channel, function tranquilizing by nourishing the heart, loosening bowel to relieve constipation.< < Sheng Nong's herbal classic > > carries: " the main palpitation with fear of Semen Platycladi, settling five organs, QI invigorating, main arthralgia chiefly caused by damp pathogen.Clothes make us moist beauty for a long time, and normal hearing and eyesight is not hungry not old, makes light of one's life by commiting suicide and prolongs life." cure mainly cardiopalmus, insomnia, forgetful due to deficiency of heart-blood; Constipation due to night sweat due to deficiency of kidney yin and deficiency of YIN dryness of the intestine.
Radix Et Caulis Acanthopanacis Senticosi is Araliaceae Radix Et Caulis Acanthopanacis Senticosi
acanthopanax senticosus (Rupr.et Maxim.)dry root and rhizome.The micro-hardship of Radix Et Caulis Acanthopanacis Senticosi acrid in the mouth warm in nature, < < Compendium of Materia Medica > > records " Radix Et Caulis Acanthopanacis Senticosi energy benefit power benefit essence, the improving eyesight therapeutic method to keep the adverse QI flowing downwards ", " can mend five kinds of strain and seven kinds of impairment.Clothes are made light of one's life by commiting suicide resistance to old for a long time "; The merit with replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization.Containing multiple glycosides compound, its main component is eleutheroside A (trailing plants I, glycosides recklessly), Syringin (ligustrin), Radix Acanthopanacis Senticosi glycosides B2 (7-hydroxyl 6,8-dimethyl coumarin essence glucoside), Radix Et Caulis Acanthopanacis Senticosi glucoside C (galactite glycosides), eleutheroside D and E (glucoside of syringaresinol 2 kinds not isomorphism type), and Radix Et Caulis Acanthopanacis Senticosi glucoside F and G.In addition also have the compositions such as ferulic acid glucoside, caffeic acid, sinapyladehyde, isofraxidin and sesamin.Total glycosides content reaches 0.6%～0.8%, wherein containing main active such as isofraxidins (isofraxidin).Modern pharmacology proves, Radix Et Caulis Acanthopanacis Senticosi can strengthen human body resisting fatigue and adaptability, radioprotective, adjusting leukocyte, have the immunity of adjusting and antitumaous effect.
The present invention, with Semen Ziziphi Spinosae, Ganoderma, Semen Platycladi and Radix Et Caulis Acanthopanacis Senticosi prescription, has the function of improving sleep quality.There is no at present this Chinese prescription for improving sleep.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition that improves sleep quality.
The proportioning of Chinese medicine composition of the present invention is formulated by following compositions in weight percentage: Semen Ziziphi Spinosae 20%～50%, Ganoderma 10%～30%, Semen Platycladi 10%～30%, Radix Et Caulis Acanthopanacis Senticosi 10%～40%.
The good proportioning of Chinese medicine composition of the present invention is formulated by following compositions in weight percentage: Semen Ziziphi Spinosae 30%～40%, Ganoderma 15%～25%, Semen Platycladi 15%～20%, Radix Et Caulis Acanthopanacis Senticosi 20%～30%.
Chinese medicine composition optimum ratio of the present invention is, formulated by following compositions in weight percentage: Semen Ziziphi Spinosae 37%, Ganoderma 18%, Semen Platycladi 18%, Radix Et Caulis Acanthopanacis Senticosi 27%.
Semen Ziziphi Spinosae in Chinese medicine composition of the present invention, Ganoderma, Semen Platycladi and Radix Et Caulis Acanthopanacis Senticosi, can be both Chinese crude drug or the prepared slices of Chinese crude drugs, can be also the extract of corresponding Chinese medicine.
Another object of the present invention is that above Chinese medicine composition improves the medicine of sleep and the application in health food in preparation.
Above-mentioned Chinese medicine composition can be directly medicinal, also can be by adding the dosage forms such as pharmaceutic adjuvant granulation, capsule, tablet, pill and oral liquid to use.
specific embodiment:
Below by test example, further set forth the beneficial effect of Chinese medicine composition of the present invention.
Test example Chinese medicine composition of the present invention improves the experimentation of sleep function.
1 materials and methods
1.1 sample
Chinese medicine composition of the present invention, human body recommended intake is 1.2g/ people/day (being equivalent to 0.02g/kg.bw).Experiment before with distilled water diluting to desired concn.
1.2 laboratory animals and raising
The female ICR kind of SPF level mice, body weight 18～22g, by Chengdu, Da Shuo bio tech ltd provides, the animal quality certification number: SCXK(river) 2008-24.Raising condition: barrier level Animal House [credit number: the SYXK(of management of laboratory animal committee river, Sichuan Province) 2011-011].
1.3 dosage groupings and given the test agent give the time
Laboratory animal adaptability is divided into 4 groups after feeding immediately, i.e. blank group and Chinese medicine composition 0.20g/kg.bw of the present invention, 0.40g/kg.bw, tri-dosage groups of 0.60g/kg.bw (be equivalent to respectively human body recommended intake 1.2g/ people/day 10,20,30 times).Chinese medicine composition of the present invention is accurately taken respectively to 0.40g, 0.80g, 1.20g and is dissolved in 40ml distilled water, as basic, normal, high three dosage group gavage liquid.By 2% volume gavage every day once, continuous 30 days.Blank group is used equal-volume distilled water.
1.4 experimental technique
1.4.1 directly sleep each treated animal of experimental observation after giving given the test agent, the phenomenon that whether occurs sleeping (sleep be take righting reflex loss as index).
1.4.2 extend pentobarbital sodium test the length of one's sleep last gavage given the test agent or distilled water after 30 minutes to each treated animal lumbar injection pentobarbital sodium 45mg/kg.bw, observe and record and inject sleep (the losing righting reflex) persistent period of animal afterwards.Calculate respectively the average length of one's sleep of each treated animal.
1.4.3 pentobarbital sodium sub-threshold dose hypnosis test last gavage given the test agent or distilled water are after 30 minutes, press 27mg/kg.bw dosage to each treated animal lumbar injection pentobarbital sodium normal saline solution, observe the number of animals of falling asleep (righting reflex loss of take surpasses 1 minute standard of falling asleep as judgement) of injecting in latter 30 minutes.Calculate respectively the sleep incidence rate of each treated animal.
1.4.4 barbital sodium Sleep latency test last gavage given the test agent or distilled water are given each treated animal lumbar injection barbital sodium 240mg/kg.bw after 30 minutes, observe and record the Sleep latency of the rear animal of injection.Calculate respectively the average Sleep latency (being time for falling asleep-injection barbital sodium time) of each treated animal.
1.5 experimental data statistics
Experimental data is carried out variance analysis with PEMS for Windows 3.1 statistical packages.Sleep incidence rate is used X 2 test; The length of one's sleep, Sleep latency and body weight user difference analysis are checked.
2 results
2.1 Chinese medicine compositions of the present invention on the impact of Mouse Weight in Table 1～table 3.
Table 1～table 3 shows, Mouse Weight there was no significant difference between three dosage groups of Chinese medicine composition of the present invention and blank group when experiment beginning, mid-term and end.
Table 1 Chinese medicine composition of the present invention on the impact of Mouse Weight (the mensuration length of one's sleep) (
± S)
Table 2 Chinese medicine composition of the present invention on the impact of Mouse Weight (rate of falling asleep mensuration) (
± S)
Table 3 Chinese medicine composition of the present invention on the impact of Mouse Weight (sleep latency) (
± S)
2.2 directly sleep tests
All there is not sleep phenomenon in each treated animal, i.e. this inspection product are without directly sleep effect after giving given the test agent.
2.3 extend the pentobarbital sodium test length of one's sleep in Table 4.
As shown in table 4, Chinese medicine composition 0.60g/kg.bw dosage group mice of the present invention is significantly longer than blank group (P<0.05) the average length of one's sleep.
Table 4 Chinese medicine composition of the present invention on the pentobarbital sodium impact of the length of one's sleep (
± S)
* with matched group comparison, P<0.05
2.4 pentobarbital sodium sub-threshold dose hypnosis tests are in Table 5.
As shown in table 5, the sleep incidence rate of of the present invention group of each dosage group mice of Chinese medicine compound and blank group be there was no significant difference relatively.
The impact of table 5 Chinese medicine composition of the present invention on sub-threshold dose pentobarbital sodium induced hypnotic incidence rate
2.5 barbital sodium Sleep latency tests are in Table 6.
As shown in table 6, the Sleep latency of Chinese medicine composition 0.60g/kg.bw dosage group mice of the present invention is significantly shorter than blank group (P<0.05).
Table 6 Chinese medicine composition of the present invention is black take off element on the preclinical impact of mice sleep of barbital sodium induction (
± S)
* with matched group comparison, P<0.05
3 brief summaries
Adopt the female ICR kind of SPF level mice, Chinese medicine composition of the present invention is pressed 10,20,30 times of continuous gavages 30 days of human body recommended dose, and result shows, Chinese medicine composition of the present invention has no adverse effects to weight of mice, and without directly sleep effect.0.60g/kg.bw dosage group mice is significantly longer than blank group (P<0.05) the average length of one's sleep, and Sleep latency is significantly shorter than blank group (P<0.05).According to evaluation criterion, Chinese medicine composition of the present invention has the sleep function of improvement.
Below by specific embodiment, the present invention is further illustrated.
Embodiment 1
Get Semen Ziziphi Spinosae extract 134g, Ganoderma extract 66g, Semen Platycladi extract 66g, Radix Et Caulis Acanthopanacis Senticosi extract 100g, starch 32.5g, silica 1 .5g, above powder is crossed respectively 60 mesh sieves, and mix homogeneously is encapsulated.
Embodiment 2
Get Semen Ziziphi Spinosae 900g, Semen Platycladi 600g, Radix Et Caulis Acanthopanacis Senticosi 900g coarse pulverization, adds 10-30 times of water gaging and decocts 1～3 time, and each 0.5～3 hour, filter, medicinal liquid is concentrated into about 1:1, is spray dried to powder, standby; Ganoderma 600g is beaten to powder and sieve, mix homogeneously with above-mentioned powder, make powder.
Embodiment 3
Get Semen Ziziphi Spinosae 1000g, Semen Platycladi 400g, Radix Et Caulis Acanthopanacis Senticosi 200g coarse pulverization, adds 20 times of water gagings and decocts 2 times, and each 2 hours, filter, medicinal liquid is concentrated into about 1:1, is spray dried to powder, standby; Ganoderma 400g is beaten to powder and sieve, add above-mentioned powder and adjuvant, mix homogeneously, granulates, and dry, granulate, adds magnesium stearate, and tabletting is made tablet.
Embodiment 4
Get Semen Ziziphi Spinosae extract 120g, Ganoderma extract 45g, Semen Platycladi extract 45g, Radix Et Caulis Acanthopanacis Senticosi extract 90g, mix homogeneously, sterilizing, packs in bag bubble health tea filter paper bag, and sealing, obtains teabag.
Claims (6)
1. a Chinese medicine composition that improves sleep quality, is characterized in that, formulated by following compositions in weight percentage: Semen Ziziphi Spinosae 20%～50%, Ganoderma 10%～30%, Semen Platycladi 10%～30%, Radix Et Caulis Acanthopanacis Senticosi 10%～40%.
2. Chinese medicine composition according to claim 1, is characterized in that, formulated by following compositions in weight percentage: Semen Ziziphi Spinosae 30%～40%, Ganoderma 15%～25%, Semen Platycladi 15%～20%, Radix Et Caulis Acanthopanacis Senticosi 20%～30%.
3. Chinese medicine composition according to claim 1, is characterized in that, formulated by following compositions in weight percentage: Semen Ziziphi Spinosae 37%, Ganoderma 18%, Semen Platycladi 18%, Radix Et Caulis Acanthopanacis Senticosi 27%.
4. according to the Chinese medicine composition described in claim 1,2 or 3, wherein Semen Ziziphi Spinosae, Ganoderma, Semen Platycladi and Radix Et Caulis Acanthopanacis Senticosi can be Chinese crude drug or the prepared slices of Chinese crude drugs, can be also the extracts of corresponding Chinese medicine.
5. according to the Chinese medicine composition described in claim 1,2 or 3, in preparation, improve the application in sleep medicine and health food.
6. can be directly medicinal according to the Chinese medicine composition described in claim 1,2 or 3, also can be by adding the dosage forms such as pharmaceutic adjuvant granulation, capsule, tablet, pill and oral liquid to use.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410327414.5A CN104055871A (en) | 2014-07-10 | 2014-07-10 | Traditional Chinese medicinal composition for improving sleeping quality and application of traditional Chinese medicinal composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410327414.5A CN104055871A (en) | 2014-07-10 | 2014-07-10 | Traditional Chinese medicinal composition for improving sleeping quality and application of traditional Chinese medicinal composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104055871A true CN104055871A (en) | 2014-09-24 |
Family
ID=51543990
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410327414.5A Pending CN104055871A (en) | 2014-07-10 | 2014-07-10 | Traditional Chinese medicinal composition for improving sleeping quality and application of traditional Chinese medicinal composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104055871A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104383404A (en) * | 2014-10-28 | 2015-03-04 | 海南制药厂有限公司 | Extract and preparation with functions of improving sleep and regulating immunity and preparation method of extract |
| CN105124600A (en) * | 2015-08-24 | 2015-12-09 | 杭州娃哈哈科技有限公司 | Composition with a sleep-improving function and application thereof |
| CN107375460A (en) * | 2017-07-21 | 2017-11-24 | 成都柏图生物科技有限公司 | It is a kind of that there is improvement sleep, antifatigue, anti-aging pharmaceutical composition and preparation method |
| CN108041603A (en) * | 2018-01-30 | 2018-05-18 | 哈尔滨快好药业有限公司 | It is a kind of that there is health food for improving sleep effect and its preparation method and application |
| CN109700011A (en) * | 2019-01-23 | 2019-05-03 | 王鸿雁 | A kind of health food and preparation method thereof improving sleep |
| CN111919931A (en) * | 2020-08-14 | 2020-11-13 | 云南东方甘霖茶叶股份有限公司 | Health tea for clearing liver, improving eyesight and helping sleep |
| CN114009773A (en) * | 2021-10-14 | 2022-02-08 | 宁夏医科大学 | Composition with sleep improving effect and preparation method and application thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1528173A (en) * | 2003-10-20 | 2004-09-15 | 中国农业科学院蜜蜂研究所 | Royal jelly composition with improved sleep function |
| CN101513493A (en) * | 2008-02-22 | 2009-08-26 | 北京天科仁祥医药科技有限公司 | Medicinal composition for treating insomnia, and preparation method thereof |
| CN102188610A (en) * | 2011-02-01 | 2011-09-21 | 完美（中国）有限公司 | Chinese medicinal composition with effect of improving sleeping and preparation method thereof |
| CN103589610A (en) * | 2013-11-20 | 2014-02-19 | 蔡焱 | Production method of nerve calming wine |
-
2014
- 2014-07-10 CN CN201410327414.5A patent/CN104055871A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1528173A (en) * | 2003-10-20 | 2004-09-15 | 中国农业科学院蜜蜂研究所 | Royal jelly composition with improved sleep function |
| CN101513493A (en) * | 2008-02-22 | 2009-08-26 | 北京天科仁祥医药科技有限公司 | Medicinal composition for treating insomnia, and preparation method thereof |
| CN102188610A (en) * | 2011-02-01 | 2011-09-21 | 完美（中国）有限公司 | Chinese medicinal composition with effect of improving sleeping and preparation method thereof |
| CN103589610A (en) * | 2013-11-20 | 2014-02-19 | 蔡焱 | Production method of nerve calming wine |
Non-Patent Citations (1)
| Title |
|---|
| 肖科金,周德生: "中药提取物促进睡眠作用研究进展", 《中国中医药信息杂志》 * |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104383404A (en) * | 2014-10-28 | 2015-03-04 | 海南制药厂有限公司 | Extract and preparation with functions of improving sleep and regulating immunity and preparation method of extract |
| CN104383404B (en) * | 2014-10-28 | 2018-07-06 | 海南制药厂有限公司 | With the extract and preparation that improve sleep and adjusting immunization and preparation method |
| CN105124600A (en) * | 2015-08-24 | 2015-12-09 | 杭州娃哈哈科技有限公司 | Composition with a sleep-improving function and application thereof |
| CN107375460A (en) * | 2017-07-21 | 2017-11-24 | 成都柏图生物科技有限公司 | It is a kind of that there is improvement sleep, antifatigue, anti-aging pharmaceutical composition and preparation method |
| CN108041603A (en) * | 2018-01-30 | 2018-05-18 | 哈尔滨快好药业有限公司 | It is a kind of that there is health food for improving sleep effect and its preparation method and application |
| CN109700011A (en) * | 2019-01-23 | 2019-05-03 | 王鸿雁 | A kind of health food and preparation method thereof improving sleep |
| CN111919931A (en) * | 2020-08-14 | 2020-11-13 | 云南东方甘霖茶叶股份有限公司 | Health tea for clearing liver, improving eyesight and helping sleep |
| CN114009773A (en) * | 2021-10-14 | 2022-02-08 | 宁夏医科大学 | Composition with sleep improving effect and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104055871A (en) | Traditional Chinese medicinal composition for improving sleeping quality and application of traditional Chinese medicinal composition | |
| CN101632769B (en) | Chinese medicinal composition for regulating blood sugar and preparation method thereof | |
| CN104435748A (en) | Dendrobium officinale compound preparation as well as preparation method and application of dendrobium officinale compound preparation | |
| CN105852127A (en) | Hypoglycemic hypolipidemic health-care product and production method | |
| CN102293927B (en) | Compound Chinese medicinal preparation with antifatigue and antioxidation effects, and preparation method thereof | |
| CN102579836B (en) | Traditional Chinese medical dendrobium huoshanense composition and preparation method thereof | |
| CN101837087B (en) | Chinese medicinal composition for improving immunity, resisting fatigue and improving sexual function | |
| CN112791151B (en) | Composition with function of improving sleep and application | |
| CN105412817A (en) | Rhodiola rosea compound oral liquid and preparation method thereof | |
| CN1471845A (en) | Healthy food with glossy and rhizoma as main material and preparing method thereof | |
| CN102302609A (en) | Compound traditional Chinese drug preparation for improving subhealth | |
| CN104489647A (en) | Anti-fatigue health food containing radix astragali, eucommia, rhizoma polygonati, sea-buckthorn and ginseng and preparation method thereof | |
| CN104337920B (en) | Traditional Chinese medicine composition for improving sleep quality | |
| CN104189349B (en) | Traditional Chinese medicine composition for treating oligomenorrhea | |
| CN110876772A (en) | Preparation method and application of traditional Chinese medicine preparation with liver protection function | |
| CN103446445B (en) | Traditional Chinese medicine preparation for treating qi-yin deficiency-type chronic bronchitis and preparation method thereof | |
| CN102895387B (en) | Kidney-yang-warming medicine composition, and preparation thereof and preparation method thereof | |
| CN107801990A (en) | A kind of health food of auxiliary hyperglycemic and preparation method thereof | |
| CN104225425A (en) | Chinese herbal preparation for enhancing immunity, improving sleep and preventing cardio-cerebrovascular disease, and preparation method thereof | |
| CN101032524B (en) | Application of martianus dermestoides in producing oxygen-deficient resisting medicine or healthy food | |
| CN106474330A (en) | A kind of tranquillizing and allaying excitement alternative tea made as composition using food plant | |
| CN100398115C (en) | Medicine for treating alcohol liver damage and its preparing method | |
| CN103816234B (en) | A kind of pharmaceutical composition improving cognitive competence and its production and use | |
| CN104189833A (en) | Process for preparing xiaoyao pills | |
| CN104096073A (en) | Traditional Chinese medicine composition for treating male infertility and preparation method for same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20140924 |