CN104489647A - Anti-fatigue health food containing radix astragali, eucommia, rhizoma polygonati, sea-buckthorn and ginseng and preparation method thereof - Google Patents
Anti-fatigue health food containing radix astragali, eucommia, rhizoma polygonati, sea-buckthorn and ginseng and preparation method thereof Download PDFInfo
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- CN104489647A CN104489647A CN201410700659.8A CN201410700659A CN104489647A CN 104489647 A CN104489647 A CN 104489647A CN 201410700659 A CN201410700659 A CN 201410700659A CN 104489647 A CN104489647 A CN 104489647A
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Abstract
The invention relates to the health product industry and especially relates to an anti-fatigue health food containing radix astragali, eucommia, rhizoma polygonati, sea-buckthorn and ginseng and a preparation method thereof. The anti-fatigue health food comprises radix astragali, eucommia, rhizoma polygonati, sea-buckthorn and ginseng according to a mass ratio of 5: 3.4: 3.2: 1.7: 1.6. The anti-fatigue health food utilizes traditional Chinese medicines such as radix astragali, eucommia, rhizoma polygonati, sea-buckthorn and ginseng as raw materials, has effects of supporting right and securing the root, and replenishing qi to invigorate the spleen, has mild drug properties, is safe after long-term use, and can relieve fatigue caused by a plurality of factors.
Description
Technical field
The present invention relates to health products trade, particularly relate to a kind of fatigue resistant health food containing the Radix Astragali, the bark of eucommia, sealwort, sea-buckthorn, ginseng and preparation method thereof.
Background technology
Fatigue is one of the principal element of 21 century harm humans health.At society, because rhythm of life is accelerated, a lot of people subjects larger psychological pressure for a long time, as unreasonable rest, adjustment, if things go on like this, the vitals of health, especially corticocerebral central nervous system function will be lacked of proper care, the generation of a series of fatigue symptoms such as giddy, headache, failure of memory.
Fatigue is the source of ten thousand diseases, and it can cause, and oxygen gathers from mountain base, immunologic hypofunction etc., if eliminated not in time, disease will be comed one after another in the course of time, has a strong impact on work and the life of people.
According to World Health Organization's investigation, the whole world about has the people of more than 35% to be in fatigue state, and especially middle-aged male crowd fatigue state person is up to 60%-75%.Medical expert points out, continues overtiredly can cause a series of ill symptoms, produces " burnout syndrome ".Due to the naturally-aged of operating pressure, family burden and human organ, increasing people feels that health is not equal to before, easily tired, which type of product energy relieving fatigue sense therefore more and more to receive the concern of people with.
Summary of the invention
The object of this invention is to provide a kind of fatigue resistant health food, described fatigue resistant health food is made up of the Radix Astragali, the bark of eucommia, sealwort, sea-buckthorn, ginseng, and wherein the mass ratio of each bulk drug is 5:3.4:3.2:1.7:1.6.
Preferably, in the present invention also preferably disclose the preparation method of fatigue resistant health food, its step is as follows:
The first step: ginseng crude drug is cleaned, and pulverizes after low temperature drying, sieve, after radiation sterilization, for subsequent use;
Wherein preferably low temperature drying temperature is 60 degrees Celsius, sieves as crossing 100 mesh sieves.
Aforementioned radiation sterilizing refers to 5kGy dosage
60co radiation sterilization.
Second step, gets the Radix Astragali, the bark of eucommia, sealwort, sea-buckthorn boiling, merges decoction liquor, and filter, filtered fluid is evaporated to cream clearly,
3rd step, adopts spray-dired method to obtain dried cream powder the clear cream that second step obtains,
4th step, will obtain the ginseng pulverate's Homogeneous phase mixing obtained in dried cream powder and the first step in the 3rd step, add wetting agent and granulate, form fatigue resistant health food.
Preferably, in second step, amount of water is 12 times amount of medicinal material volume, and decocting time is preferably 2 hours.Repeatedly decoction liquor will merge, filter.Be evaporated to clearly cream time preferred reduced pressure concentration temperature 65 degrees Celsius, pressure is-0.08MPa, and the clear cream relative density obtained after reduced pressure concentration is 1.12-1.15, relative density detected temperatures 60 degrees Celsius.
Preferably, in the 4th step, described wetting agent is 85% alcohol.Mixed-powder is added 85% alcohol and make softwood, 16 mesh sieves are granulated, and less than 60 degrees Celsius dry, and the whole grain of 14 mesh sieve forms semi-finished granules.
Preferably, also include the 4th step, the fatigue resistant health food prepared is made hard capsule.
The Radix Astragali, containing number of chemical compositions such as saponins, polysaccharide, flavonoids, amino acid, trace element, choline, folic acid, having by improving body fight stress reaction ability, hypoxia-bearing capability, rising hemoglobin etc., reaching the effect of dispelling fatigue.
Bark of eucommia filling liver kidney, strengthening the bones and muscles.The bark of eucommia mainly closes the compositions such as lignanoids, iridoid glycosides, volatile oil, polysaccharide, amino acid, organic acid, sterol, phosphatide, vitamin, trace element and stearic acid.Pharmacological research shows, folium cortex eucommiae and skin decocting liquid, eucommia wine, pure eucommia bark powder and bark of eucommia compound preparation can effectively extend mouse swimming time, have the effect of alleviating physical fatigue.
Sealwort boosting qi and nourishing yin, tonifying speen and tonifying kidney.The chemical composition of sealwort mainly contains polysaccharide, saponin(e, flavonoids, amino acid, Anthraquinones, alkaloid and trace element.All have anti-through test compound Polygonatum, polygonatum oral liquid
[fatigue effect.
Sea-buckthorn strengthening spleen and nourishing stomach is promoting blood circulation and removing blood stasis.Sea-buckthorn chemical composition mainly contains flavonoids, terpene, steroid, dimension element class, protein and amino acids, oil & fat acids, volatile oil, organic acid, sugar and micro-etc.Pharmacological research shows, the full composition of sea-buckthorn can increase mouse fatigue resistance, and when mouse is swum, continent is prolonged peaceful.The sea-buckthorn essence that effective component extracting is made from fructus hippophae is to dispelling fatigue quickly, and strengthening locomitivity has desirable influence.
Ginseng reinforces vital energy, and multiple arteries and veins takes off admittedly, reinforces the spleen to benefit the lung, promoting production of body fluid and inducing sedation of the mind.Ginseng main component has ginsenoside, panaxan, panaxynol, volatile oil, low molecular peptide, amino acid, vitamin, organic acid and various trace elements.Pharmacological research effect shows, ginseng effective component's total saposins has positive role to the generation of delayed motion fatigue and the elimination that accelerates fatigue.
Cause tired reason a lot, often can not reach expected effect for certain factor merely.This product for raw material with traditional Chinese medicines such as the Radix Astragali, the bark of eucommia, sealwort, sea-buckthorn, ginsengs, is strengthened the body resistance to consolidate the constitution, is replenished qi to invigorate the spleen, and its property of medicine is gentle, and long-term taking safety, can play certain mitigation to the fatigue that many factors causes.
Detailed description of the invention
In order to understand the present invention better, below in conjunction with detailed description of the invention, illustrate the present invention further.
Embodiment 1
Take the Radix Astragali, the bark of eucommia, sealwort, sea-buckthorn, ginseng respectively according to weight ratio 5:3.4:3.2:1.7:1.6, and only make respectively, for subsequent use.
Get ginseng crude drug, crushed after being dried under the cryogenic conditions of 60 degrees Celsius, cross 100 mesh sieves, 5kGy dosage
60after Co irradiation sterilization, for subsequent use;
Then the Radix Astragali, the bark of eucommia, sealwort, sea-buckthorn boiling 2 times is got, each amount of water is the water of 12 times of volumes of medicinal material volume, each decoction 2 hours, merge decoction liquor, filter, filtered fluid, under the condition of 65 degrees Celsius and negative 0.08MPa, is evaporated to the clear cream (detected temperatures is 60 degrees Celsius) that relative density is 1.12 ~ 1.15
3rd step, the clear cream that second step obtains is adopted spray-dired method, and EAT controls at 170 ~ 190 degrees Celsius, and temperature of outgoing air controls at 75 ~ 85 degrees Celsius, obtains dried cream powder,
4th step, will obtain the ginseng pulverate's Homogeneous phase mixing obtained in dried cream powder and the first step in the 3rd step, add wetting agent 85% ethanol and support softwood, after 16 mesh sieves are granulated, dry below 60 degrees Celsius, and after the whole grain of 14 mesh sieve, mixing, filling, forms health product capsule.
Embodiment 2
In order to determine medicinal material amount of water (A) in decoction process, decoct number of times (B) and decocting time (C): take the Radix Astragali, the bark of eucommia, sealwort, sea-buckthorn according to weight ratio, select 8,10,12 times of amount of water, 1, number of times is decocted 2,3 times, decoct 1,1.5,2 hour, factor level table is in table 1, with dry extract yield, Thick many candies content for index, carry out orthogonal test.Result: during with dry extract yield for inspection target, B factor has the greatest impact, and C factor is taken second place, and A factor is minimum, and namely optimised process is A
3b
3c
3(see table 2); When taking Thick many candies as inspection target, B factor has the greatest impact, and A factor is taken second place, and C factor is minimum, and namely optimised process is A
3b
2c
3(see table 2); During with dry extract yield, Thick many candies content for inspection target, B factor has the greatest impact and has significant difference (see table 3,4); The checking of decocting test: take Radix Astragali 50g, bark of eucommia 34g, sealwort 32g, sea-buckthorn 17g, amounts to 133g, parallel three parts, tests according to the process conditions of screening, and result shows three batches all can Pass Test result (see table 5).Consider production cost and efficiency, the preferred A of technique
3b
2c
3.
Table 1. factor level table
Table 2. orthogonal test designs table and result of the test
Table 3. dry extract yield orthogonal test variance analysis tables of data
Table 4. Thick many candies content orthogonal test variance analysis tables of data
table 5. decocting process certification test data table
Embodiment 3
In order to determine wetting agent (ethanol) concentration: get the dried cream powder and ginseng fine powder that mix, granulate by different ethanol concentration, with the hardness of the difficulty or ease of grain forming and dry particle for inspection target, result proves (see table 6), use 85% alcohol granulation, grain forming is good, and hardness is moderate, even particle size, granulate quality is good.
Table 6. different ethanol concentration is granulated and is investigated tables of data
| Tested number | Wetting agent | Investigate result |
| 1 | 75% ethanol | Granulate more difficult, wet granular easily bonds; Dry pellet hardness is large |
| 2 | 85% ethanol | Granulate easily, grain forming is good; Dry pellet hardness is moderate |
| 3 | 95% ethanol | Granulation is easier to; Dry pellet hardness is moderate, and fine powder ratio is larger |
Claims (6)
1. one kind
containing the fatigue resistant health food of the Radix Astragali, the bark of eucommia, sealwort, sea-buckthorn, ginseng, it is characterized in that, wherein the mass ratio of each bulk drug is 5:3.4:3.2:1.7:1.6.
2. the preparation method of fatigue resistant health food according to claim 1, is characterized in that, its step is as follows:
The first step: ginseng crude drug is cleaned, and pulverizes after low temperature drying, sieve, after radiation sterilization, for subsequent use;
Second step, gets the Radix Astragali, the bark of eucommia, sealwort, sea-buckthorn boiling, merges decoction liquor, and filter, filtered fluid is evaporated to cream clearly,
3rd step, adopts spray-dired method to obtain dried cream powder the clear cream that second step obtains,
4th step, will obtain the ginseng pulverate's Homogeneous phase mixing obtained in dried cream powder and the first step in the 3rd step, add wetting agent and granulate, form fatigue resistant health food.
3. the preparation method of fatigue resistant health food according to claim 2, is characterized in that, in second step, amount of water is 12 times amount of medicinal material volume, and decocting time is preferably 2 hours.
4. the preparation method of fatigue resistant health food according to claim 2, it is characterized in that, in second step, be evaporated to clearly cream time preferred reduced pressure concentration temperature 65 degrees Celsius, pressure is-0.08MPa, the clear cream relative density obtained after reduced pressure concentration is 1.12-1.15, relative density detected temperatures 60 degrees Celsius.
5. the preparation method of fatigue resistant health food according to claim 2, is characterized in that, in the 4th step, described wetting agent is 85% alcohol.
6. the preparation method of fatigue resistant health food according to claim 2, is characterized in that, also includes the 4th step, the fatigue resistant health food prepared is made hard capsule.
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| CN201410700659.8A CN104489647A (en) | 2014-11-28 | 2014-11-28 | Anti-fatigue health food containing radix astragali, eucommia, rhizoma polygonati, sea-buckthorn and ginseng and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107048129A (en) * | 2017-05-11 | 2017-08-18 | 广州善康生物科技有限公司 | A kind of antifatigue crocodile polypeptide beverage |
| CN108576538A (en) * | 2018-06-12 | 2018-09-28 | 汪华东 | A kind of antifatigue crocodile composite and preparation method thereof that can refresh oneself |
| CN112617196A (en) * | 2020-11-27 | 2021-04-09 | 成都藏源高能生物科技有限公司 | Food, health-care product or pharmaceutical composition for resisting anoxia and fatigue and preparation method and application thereof |
| CN113729225A (en) * | 2021-08-30 | 2021-12-03 | 山西五台山沙棘制品有限公司 | Seabuckthorn and astragalus cream and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107048129A (en) * | 2017-05-11 | 2017-08-18 | 广州善康生物科技有限公司 | A kind of antifatigue crocodile polypeptide beverage |
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| CN112617196A (en) * | 2020-11-27 | 2021-04-09 | 成都藏源高能生物科技有限公司 | Food, health-care product or pharmaceutical composition for resisting anoxia and fatigue and preparation method and application thereof |
| CN113729225A (en) * | 2021-08-30 | 2021-12-03 | 山西五台山沙棘制品有限公司 | Seabuckthorn and astragalus cream and preparation method thereof |
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Application publication date: 20150408 |
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